Aliases & Classifications for Head Injury

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Summaries for Head Injury

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MedlinePlus:32 Chances are you've bumped your head before. usually, the injury is minor because your skull is hard and it protects your brain. but other head injuries can be more severe, such as a skull fracture, concussion, or traumatic brain injury. head injuries can be open or closed. a closed injury does not break through the skull. with an open, or penetrating, injury, an object pierces the skull and enters brain tissue. closed injuries are not always less severe than open injuries. some common causes of head injuries are falls, motor vehicle accidents, violence, and sports injuries. it is important to know the warning signs of a moderate or severe head injury. get help immediately if the injured person has a headache that gets worse or does not go away repeated vomiting or nausea convulsions or seizures an inability to wake up dilation of one or both pupils of the eyes slurred speech weakness or numbness in the arms or legs loss of coordination increased confusion, restlessness, or agitation nih: national institute of neurological disorders and stroke

MalaCards based summary: Head Injury, also known as head injuries, is related to choroid plexus papilloma and medulloblastoma. An important gene associated with Head Injury is NTF4 (neurotrophin 4), and among its related pathways are Nuclear signaling by ERBB4 and Neuroscience. The compounds eosin and s 100 have been mentioned in the context of this disorder. Affiliated tissues include brain, eye and testes, and related mouse phenotypes are homeostasis/metabolism and nervous system.

NINDS:43 Traumatic brain injury (TBI), a form of

Wikipedia:64 Any injury that results in trauma to the skull, or brain can be classified as a head injury. The terms... more...

Related Diseases for Head Injury

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Diseases related to Head Injury via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 174)
idRelated DiseaseScoreTop Affiliating Genes
1choroid plexus papilloma30.5GFAP
2medulloblastoma30.2S100B, GFAP, NUDT6
3tuberous sclerosis30.1S100B, GFAP
4dementia29.8CHAT, CHRM1, APOE, GFAP
5ischemia29.6NUDT6, GFAP, CHAT, NTF4
6cerebritis10.7
7traumatic brain injury10.6
8brain injury10.5
9neuronitis10.4
10subependymal giant cell astrocytoma10.4GFAP
11internuclear ophthalmoplegia10.4
12ophthalmoplegia10.4
13cervicitis10.4
14giant cell glioblastoma10.4GFAP
15sagittal sinus thrombosis10.4
16shaken baby syndrome10.4
17mutism10.3
18headache10.3
19blindness10.3
20hydrocephalus10.3
21retrograde amnesia10.3
22bacterial meningitis10.3
23hypopituitarism10.3
24meningitis10.3
25arachnoid cysts10.3
26aneurysm10.3
27seizure disorder10.3
28dementia, lewy body10.3APOE
29myxopapillary ependymoma10.2S100B, GFAP
30papillary ependymoma10.2GFAP, S100B
31choroid plexus carcinoma10.2S100B, GFAP
32anaplastic ependymoma10.2GFAP, S100B
33gemistocytic astrocytoma10.2GFAP, S100B
34syringoma10.2GFAP, S100B
35pineocytoma10.2GFAP, S100B
36myoepithelioma10.2S100B, GFAP
37hemangioblastoma10.2GFAP, S100B
38cortical blindness10.2
39hypokalemia10.2
40hypophosphatemia10.2
41carotid artery thrombosis10.2
42arachnoiditis10.2
43brain edema10.2
44disseminated intravascular coagulation10.2
45intracranial hypertension10.2
46retinitis10.2
47hyperlipidemia type 310.2
48post-traumatic epilepsy10.2
49cerebral atrophy10.2
50persistent vegetative state10.2

Graphical network of the top 20 diseases related to Head Injury:



Diseases related to head injury

Symptoms for Head Injury

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Drugs & Therapeutics for Head Injury

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Drug clinical trials:

Search ClinicalTrials for Head Injury

Search NIH Clinical Center for Head Injury

Genetic Tests for Head Injury

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Anatomical Context for Head Injury

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MalaCards organs/tissues related to Head Injury:

31
Brain, Eye, Testes, Pituitary, Endothelial, Bone, Neutrophil, T cells, Cortex, Spinal cord, Heart, Prostate

Animal Models for Head Injury or affiliated genes

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MGI Mouse Phenotypes related to Head Injury:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053767.7FABP7, CHAT, CHRM1, APOE, GFAP
2MP:00036317.0GFAP, APOE, CHRM1, CHAT, FABP7, NTF4
3MP:00053866.8S100B, GFAP, APOE, CHRM1, CHAT, FABP7

Publications for Head Injury

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Articles related to Head Injury:

(show top 50)    (show all 741)
idTitleAuthorsYear
1
Brief account on the head injury of a noble youngster in the sixteenth century (Prince Don Carlos, heir to Philip II of Spain, 1545-1568). (25837577)
2015
2
Head injury and risk for Parkinson disease: Results from a Danish case-control study. (25681453)
2015
3
Closed head injury in an age-related Alzheimer mouse model leads to an altered neuroinflammatory response and persistent cognitive impairment. (25904805)
2015
4
Head Injury in Children: Has a Change in Circumstances Caused an Increase in Treatment Numbers? (25370862)
2014
5
Visualisation of the intact dura mater and brain surface in infant autopsies: a minimally destructive technique for the post-mortem assessment of head injury. (25384986)
2014
6
Imaging of pediatric head injury in the emergency department. (25272077)
2014
7
Head injury. (23431655)
2013
8
Batting head injury in professional cricket: a systematic video analysis of helmet safety characteristics. (23418269)
2013
9
Pneumonia in patients with severe head injury: incidence, risk factors, and outcomes. (23157183)
2013
10
Predicting mortality from head injury: experience of Sancti SpA-ritus province, Cuba. (23934424)
2013
11
Late-onset sensorineural hearing loss due to congenital cytomegalovirus infection: could head injury be a trigger? (23025246)
2013
12
An analysis of predictive markers for intracranial haemorrhage in warfarinised head injury patients. (22362648)
2013
13
Epidemiology of paediatric minor head injury: Comparison of injury characteristics with Indices of Multiple Deprivation. (23958554)
2013
14
Urgent intracranial carotid artery decompression after penetrating head injury. (23634269)
2013
15
Early postinjury exercise reverses memory deficits and retards the progression of closed-head injury in mice. (23184513)
2013
16
Computed tomography after decompressive craniectomy for head injury. (23564139)
2013
17
Delayed neurological deterioration after mild head injury: cause, temporal course, and outcomes. (23867298)
2013
18
Annals of Emergency Medicine Journal Club. Biomarkers revisited: study design, validity, and STARD: Will S100-B affect computed tomography use in head injury patients?: Answers to the March 2012 Journal Club questions. (22818373)
2012
19
Role of hyperbaric oxygen therapy in severe head injury in children. (22837768)
2012
20
Carotid artery dissection presenting with isolated headache and Horner syndrome after minor head injury. (22633727)
2012
21
In vivo bioluminescent imaging of a new model of infectious complications in head-injury rats. (21806472)
2012
22
Head injury or head motion? Assessment and quantification of motion artifacts in diffusion tensor imaging studies. (21391258)
2012
23
Serum levels of protein S100B predict intracranial lesions in mild head injury. (22285378)
2012
24
Predicting the need for CT imaging in children with minor head injury using an ensemble of Naive Bayes classifiers. (22196718)
2012
25
Chest injuries associated with head injury. (24027384)
2012
26
A microdialysis study of oral vigabatrin administration in head injury patients: preliminary evaluation of multimodality monitoring. (22327707)
2012
27
Outcome analysis and outcome predictors of traumatic head injury in childhood: Analysis of 454 observations. (21769206)
2011
28
Clinical decision rules for children with minor head injury: a systematic review. (21310894)
2011
29
Tectorial membrane injury: frequently overlooked in pediatric traumatic head injury. (21852371)
2011
30
Comparative yield of positive brain computed tomography after implementing the NICE or SIGN head injury guidelines in two equivalent urban populations. (21296343)
2011
31
Controversial treatment of a victim of severe head injury complicated by septic shock and acute respiratory distress syndrome. (23754904)
2011
32
Head injury causation scenarios for belted, rear-seated children in frontal impacts. (21259175)
2011
33
Prognostic value of magnetic resonance imaging in moderate and severe head injury: a prospective study of early MRI findings and one-year outcome. (21401308)
2011
34
White-eyed medial wall blowout fracture mimicking head injury due to persistent oculocardiac reflex. (21959489)
2011
35
Coagulopathy in moderate head injury. The role of early administration of low molecular weight heparin. (20642324)
2010
36
Six nails in the head: multiple pneumatic nail gun head injury. (20726759)
2010
37
CATCH: a clinical decision rule for the use of computed tomography in children with minor head injury. (20142371)
2010
38
Automated assessment of midline shift in head injury patients. (20663606)
2010
39
Severe head injury: control of physiological variables, organ failure and complications in the intensive care unit. (17711565)
2007
40
Oxidative damage after severe head injury and its relationship to neurological outcome. (12234402)
2002
41
Anterior hypopituitarism with unusual delayed onset of diabetes insipidus after penetrating head injury. (12362120)
2002
42
Soluble adhesion molecules in CSF are increased in children with severe head injury. (9814634)
1998
43
Transient global amnesia triggered by mild head injury. (9653523)
1998
44
Motor and cognitive deficits in apolipoprotein E-deficient mice after closed head injury. (9284075)
1997
45
HM-PAO-SPECT in persistent vegetative state after head injury: prognostic indicator of the likelihood of recovery? (2071761)
1991
46
Severe head injury: effect upon cellular immune function. (1675441)
1991
47
Accommodative esotropia after ocular and head injury. (2301531)
1990
48
Paroxysmal choreoathetosis after head injury. (3746316)
1986
49
Internal carotid artery thrombosis secondary to closed head injury. (5434376)
1970
50
Intracranial thrombosis of the internal carotid artery after closed head injury. (5360046)
1969

Variations for Head Injury

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Expression for genes affiliated with Head Injury

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Search GEO for disease gene expression data for Head Injury.

Pathways for genes affiliated with Head Injury

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Pathways related to Head Injury according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.5S100B, GFAP
28.3S100B, FABP7, APOE, GFAP

Compounds for genes affiliated with Head Injury

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Compounds related to Head Injury according to GeneCards Suite gene sharing:

(show top 50)    (show all 77)
idCompoundScoreTop Affiliating Genes
1eosin449.9S100B, GFAP
2s 100449.9GFAP, S100B
32,3-cyclic nucleotide449.8S100B, GFAP
4reticulin449.8S100B, GFAP
5propentofylline449.7GFAP, CHAT
6edss449.6APOE, S100B
7scopolamine44 28 24 1112.6CHAT, CHRM1
8pirenzepine44 28 1111.5CHRM1, CHAT
9homovanillic acid44 2410.5GFAP, CHAT
10quinolinic acid44 2410.4GFAP, CHAT, NTF4
11bromodeoxyuridine449.3NUDT6, GFAP, S100B
12benzodiazepine449.3CHAT, GFAP
13formaldehyde44 2410.2CHAT, GFAP, S100B
145-hydroxytryptamine449.2CHAT, CHRM1, GFAP
15l-amino acid449.1S100B, CHAT
16adenylate449.1GFAP, S100B, NTF4, CHRM1
17streptozotocin449.0NUDT6, GFAP, APOE
18donepezil44 50 24 1112.0APOE, CHRM1, CHAT
19olanzapine44 50 28 24 1113.0APOE, CHAT, CHRM1
20methionine448.9S100B, NUDT6, GFAP
21cocaine44 119.9S100B, CHAT, CHRM1, GFAP
22potassium44 24 1110.8CHRM1, S100B, CHAT, GFAP
23nicotine44 28 50 1111.8CHRM1, APOE, CHAT
24dbc-amp448.8NUDT6, GFAP, S100B, CHAT
25cyclic amp44 249.8CHAT, GFAP, S100B, CHRM1
26lactate448.8CHAT, GFAP, NUDT6, S100B
27phosphatidylinositol448.7NUDT6, CHRM1, CHAT, NTF4
28ethanol44 50 24 1111.6NTF4, CHRM1, S100B, CHAT, GFAP
29gaba448.5CHRM1, GFAP, S100B, CHAT, FABP7
30nitric oxide44 24 1110.5CHRM1, CHAT, S100B, NUDT6
31paraffin448.5CHAT, APOE, GFAP, S100B
32forskolin44 50 1110.5GFAP, NUDT6, CHAT, NTF4, S100B
33aspartate448.4CHAT, APOE, GFAP, S100B
34vegf448.4NUDT6, S100B, GFAP, APOE
35kainate44 289.4GFAP, NUDT6, CHAT, APOE
36atp44 289.3NUDT6, GFAP, CHRM1, CHAT, S100B
37serine448.1APOE, GFAP, NUDT6, NTF4, S100B
38estrogen448.1S100B, APOE, GFAP, CHAT
39retinoic acid44 249.1S100B, CHAT, NTF4, GFAP, NUDT6, FABP7
40nmda44 289.1NUDT6, CHAT, NTF4, APOE, GFAP
41choline44 24 1110.0NTF4, GFAP, CHRM1, S100B, CHAT, NUDT6
42tyrosine448.0CHRM1, NUDT6, S100B, NTF4, CHAT, GFAP
43testosterone44 60 24 1111.0GFAP, APOE, CHAT, S100B, NUDT6
44calcium44 50 24 1111.0S100B, NTF4, CHAT, CHRM1, NUDT6, GFAP
45arginine447.8S100B, NTF4, NUDT6, GFAP, APOE, CHRM1
46alanine447.7S100B, CHRM1, NTF4, GFAP, APOE, CHAT
47lipid447.7S100B, FABP7, CHAT, CHRM1, APOE, GFAP
48dopamine44 28 24 1110.6GFAP, APOE, CHRM1, CHAT, S100B, NUDT6
49acetylcholine44 50 28 24 1111.2CHAT, CHRM1, GFAP, NUDT6, NTF4, S100B
50glutamate446.9APOE, GFAP, CHRM1, CHAT, FABP7, NTF4

GO Terms for genes affiliated with Head Injury

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Cellular components related to Head Injury according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1neuronal cell bodyGO:00430258.2S100B, FABP7, CHAT, APOE

Biological processes related to Head Injury according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1long-term synaptic potentiationGO:00602919.5S100B, GFAP
2regulation of neuronal synaptic plasticityGO:00481689.1S100B, APOE
3neuromuscular synaptic transmissionGO:00072749.1CHAT, CHRM1

Molecular functions related to Head Injury according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1tau protein bindingGO:00481569.2S100B, APOE

Sources for Head Injury

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet