Aliases & Classifications for Head Injury

MalaCards integrated aliases for Head Injury:

Name: Head Injury 50
Head Injuries 40

Classifications:



External Ids:

ICD10 32 S09.8 S09.9

Summaries for Head Injury

MedlinePlus : 40 Chances are you've bumped your head before. Often, the injury is minor because your skull is hard and it protects your brain. But other head injuries can be more severe, such as a skull fracture, concussion, or traumatic brain injury. Head injuries can be open or closed. A closed injury does not break through the skull. With an open, or penetrating, injury, an object pierces the skull and enters the brain. Closed injuries are not always less severe than open injuries. Some common causes of head injuries are falls, motor vehicle accidents, violence, and sports injuries. It is important to know the warning signs of a moderate or severe head injury. Get help immediately if the injured person has A headache that gets worse or does not go away Repeated vomiting or nausea Convulsions or seizures An inability to wake up Dilated (enlarged) pupil in one or both eyes Slurred speech Weakness or numbness in the arms or legs Loss of coordination Increased confusion, restlessness, or agitation Doctors use a neurologic exam and imaging tests to make a diagnosis. Treatment depends on the type of injury and how severe it is. NIH: National Institute of Neurological Disorders and Stroke

MalaCards based summary : Head Injury, also known as head injuries, is related to traumatic brain injury and intracranial cysts. An important gene associated with Head Injury is APOE (Apolipoprotein E), and among its related pathways/superpathways is Neuroscience. The drugs Ethanol and Heparin have been mentioned in the context of this disorder. Affiliated tissues include brain, eye and testes, and related phenotypes are behavior/neurological and homeostasis/metabolism

NINDS : 50 Traumatic brain injury (TBI), a form of acquired brain injury, occurs when a sudden trauma causes damage to the brain. TBI can result when the head suddenly and violently hits an object, or when an object pierces the skull and enters brain tissue.  Symptoms of a TBI can be mild, moderate, or severe, depending on the extent of the damage to the brain. A person with a mild TBI may remain conscious or may experience a loss of consciousness for a few seconds or minutes. Other symptoms of mild TBI include headache, confusion, lightheadedness, dizziness, blurred vision or tired eyes, ringing in the ears, bad taste in the mouth, fatigue or lethargy, a change in sleep patterns, behavioral or mood changes, and trouble with memory, concentration, attention, or thinking.  A person with a moderate or severe TBI may show these same symptoms, but may also have a headache that gets worse or does not go away, repeated vomiting or nausea, convulsions or seizures, an inability to awaken from sleep, dilation of one or both pupils of the eyes, slurred speech, weakness or numbness in the extremities, loss of coordination, and increased confusion, restlessness, or agitation.

Wikipedia : 72 A head injury is any injury that results in trauma to the skull or brain. The terms traumatic brain... more...

Related Diseases for Head Injury

Diseases related to Head Injury via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 216)
# Related Disease Score Top Affiliating Genes
1 traumatic brain injury 32.3 APOE ENO2 S100B
2 intracranial cysts 31.7 ENO2 S100B
3 hydrocephalus 31.3 APOE ENO2 PRL
4 brain injury 30.4 APOE ENO2 S100B
5 persistent vegetative state 30.2 APOE ENO2
6 spondylosis 29.7 ENO2 S100B
7 alexia 29.7 APOE LBR
8 stroke, ischemic 29.6 APOE ENO2 THBD
9 parkinson disease, late-onset 28.8 APOE CHAT SOD1
10 alzheimer disease 28.4 APOE CHAT S100B SOD1
11 arachnoid cysts 11.2
12 seizure disorder 11.2
13 dementia pugilistica 11.2
14 epilepsy 11.1
15 headache 11.1
16 hyperacusis 11.0
17 lennox-gastaut syndrome 10.9
18 diarrhea 5, with tufting enteropathy, congenital 10.7
19 leukoencephalopathy, hereditary diffuse, with spheroids 10.7
20 aphasia 10.7
21 diabetes insipidus, neurohypophyseal 10.7
22 cerebral palsy 10.7
23 bednar tumor 10.4 ENO2 S100B
24 epithelioid malignant peripheral nerve sheath tumor 10.4 ENO2 S100B
25 middle cerebral artery infarction 10.4 ENO2 S100B
26 ossifying fibromyxoid tumor 10.4 ENO2 S100B
27 pineocytoma 10.4 ENO2 S100B
28 papillary ependymoma 10.4 ENO2 S100B
29 subependymal giant cell astrocytoma 10.4 ENO2 S100B
30 senile plaque formation 10.4 APOE CHAT
31 granular cell tumor 10.4 ENO2 S100B
32 meningeal melanocytoma 10.3 ENO2 S100B
33 olfactory neuroblastoma 10.3 ENO2 S100B
34 rete testis adenocarcinoma 10.3 ENO2 THBD
35 cerebral primitive neuroectodermal tumor 10.3 ENO2 S100B
36 rete testis neoplasm 10.3 ENO2 THBD
37 pilomatrixoma 10.3 ENO2 S100B
38 optic nerve glioma 10.3 ENO2 S100B
39 pericardium cancer 10.3 ENO2 THBD
40 acute mountain sickness 10.3 ENO2 S100B
41 extraosseous ewing's sarcoma 10.3 ENO2 S100B
42 pericardial mesothelioma 10.3 ENO2 THBD
43 ganglioglioma 10.3 ENO2 S100B
44 secondary progressive multiple sclerosis 10.3 ENO2 S100B
45 bone ewing's sarcoma 10.2 CHAT ENO2
46 malignant teratoma 10.2 BCL2 ENO2
47 neurilemmoma 10.2 ENO2 S100B
48 cerebritis 10.2
49 clear cell sarcoma 10.2 ENO2 S100B
50 hidradenocarcinoma 10.2 BCL2 S100B

Graphical network of the top 20 diseases related to Head Injury:



Diseases related to Head Injury

Symptoms & Phenotypes for Head Injury

MGI Mouse Phenotypes related to Head Injury:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.06 APOE BCL2 CHAT ENO2 LBR PRL
2 homeostasis/metabolism MP:0005376 9.97 APOE BCL2 CHAT LBR PRL S100B
3 growth/size/body region MP:0005378 9.95 APOE BCL2 CHAT ENO2 LBR SOD1
4 integument MP:0010771 9.87 APOE BCL2 LBR PRL S100B SOD1
5 nervous system MP:0003631 9.86 PRL SOD1 THBD APOE BCL2 CHAT
6 digestive/alimentary MP:0005381 9.83 APOE BCL2 CHAT LBR THBD
7 reproductive system MP:0005389 9.7 APOE BCL2 CHAT LBR PRL SOD1
8 respiratory system MP:0005388 9.35 APOE CHAT ENO2 LBR THBD
9 vision/eye MP:0005391 9.02 APOE BCL2 CHAT LBR SOD1

Drugs & Therapeutics for Head Injury

Drugs for Head Injury (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 548)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ethanol Approved Phase 4,Phase 3,Phase 2 64-17-5 702
2
Heparin Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 9005-49-6 46507594 772
3
Norepinephrine Approved Phase 4,Phase 2 51-41-2 439260
4
Dopamine Approved Phase 4,Phase 2,Phase 3,Phase 1 51-61-6, 62-31-7 681
5
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 50-02-2 5743
6
Mannitol Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 69-65-8 6251 453
7
Zinc Approved, Investigational Phase 4 7440-66-6 32051 23994
8
Aspirin Approved, Vet_approved Phase 4,Phase 2 50-78-2 2244
9
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 2,Phase 1 59467-70-8 4192
10
Diclofenac Approved, Vet_approved Phase 4 15307-86-5 3033
11
Morphine Approved, Investigational Phase 4,Phase 1,Phase 2 57-27-2 5288826
12
Acetaminophen Approved Phase 4,Phase 2,Phase 1 103-90-2 1983
13
Ibuprofen Approved Phase 4,Phase 2 15687-27-1 3672
14
Galantamine Approved Phase 4,Phase 2 357-70-0 9651
15
Methylphenidate Approved, Investigational Phase 4,Phase 2,Phase 1 20748-11-2, 113-45-1 4158
16
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 2,Phase 1 76631-46-4, 113775-47-6 5311068 56032 68602
17
Sevoflurane Approved, Vet_approved Phase 4,Phase 2 28523-86-6 5206
18 Cisatracurium Approved, Experimental Phase 4 96946-41-7
19
Remifentanil Approved Phase 4 132875-61-7 60815
20
Citalopram Approved Phase 4 59729-33-8 2771
21
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 2078-54-8 4943
22
Amantadine Approved Phase 4,Phase 2,Phase 3,Phase 1 768-94-5 2130
23
Benzocaine Approved, Investigational Phase 4,Phase 2,Phase 1 1994-09-7, 94-09-7 2337
24
Sufentanil Approved, Investigational Phase 4,Phase 2 56030-54-7 41693
25
Phenytoin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 57-41-0 1775
26
Cocaine Approved, Illicit Phase 4,Phase 1 50-36-2 446220 5760
27
Testosterone Approved, Investigational Phase 4 58-22-0 6013
28
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757
29
Quinidine Approved, Investigational Phase 4,Phase 2 56-54-2 441074
30
Rivastigmine Approved, Investigational Phase 4,Phase 3 123441-03-2 77991
31
Acetylcholine Approved Phase 4,Phase 3,Phase 2 51-84-3 187
32
Memantine Approved, Investigational Phase 4 19982-08-2 4054
33 Piracetam Approved, Investigational Phase 4,Phase 3,Phase 2 7491-74-9
34
Propranolol Approved, Investigational Phase 4,Phase 2,Phase 1 525-66-6 4946
35
Topiramate Approved Phase 4,Early Phase 1 97240-79-4 5284627
36
Fosphenytoin Approved, Investigational Phase 4,Phase 3 93390-81-9 56339
37
Norgestimate Approved, Investigational Phase 4 35189-28-7 6540478
38
Tranexamic Acid Approved Phase 4,Phase 3,Phase 2,Phase 1 1197-18-8 5526
39
Exenatide Approved, Investigational Phase 4 141758-74-9 15991534
40
Moxifloxacin Approved, Investigational Phase 4 151096-09-2, 354812-41-2 152946
41
Dextromethorphan Approved Phase 4,Phase 3 125-71-3 5362449 5360696
42
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
43
Guaifenesin Approved, Investigational, Vet_approved Phase 4,Phase 2 93-14-1 3516
44
Methyltestosterone Approved Phase 4 58-18-4 6010
45
Dalteparin Approved Phase 4 9005-49-6
46
Thrombin Approved, Investigational Phase 4,Phase 3,Phase 1
47
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
48
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
49
Pravastatin Approved Phase 4 81093-37-0 54687
50
Simvastatin Approved Phase 4 79902-63-9 54454

Interventional clinical trials:

(show top 50) (show all 1484)

# Name Status NCT ID Phase Drugs
1 Does Discontinuation of Aspirin Treatment Following Head Trauma Decrease the Incidence of Chronic Subdural Hematoma? Unknown status NCT01470040 Phase 4 discontinuation of aspirin therapy;continuation of aspirin therapy
2 Oxepa in Multiple Trauma Unknown status NCT01099501 Phase 4
3 Galantamine in the Treatment of Post-Traumatic Headache Unknown status NCT00219869 Phase 4 Galantamine
4 Lactate and Hypoglycemia Unknown status NCT01387477 Phase 4 Lactate;Glucose
5 Antispastic Effect of Transcranial Magnetic Stimulation in Patients With Cerebral and Spinal Spasticity Unknown status NCT01786005 Phase 4
6 NIMIP: Non Invasive Measurement of the Intracranial Pressure Unknown status NCT01685450 Phase 4
7 Comparison Study of 3-4-screws-internal Fixation With Multi-screw-system Targon FN for Femoral Neck Fracture Unknown status NCT00829725 Phase 4
8 Intensive Versus Nonintensive Insulin Therapy for Hyperglycemia After Traumatic Brain Injury Unknown status NCT02161055 Phase 4 Insulin
9 A Clinical Trial of the Effect of Midazolam on the Cerebral Metabolism and Inflammatory Response in Patients With Moderate and Severe Traumatic Brain Injury Unknown status NCT02071407 Phase 4 Midazolam;Placebo
10 A Comparison of Propofol Versus Midazolam to Sedate Critically Brain Injury; Measurement of Cytokine Response and Assessment of Function Unknown status NCT01712477 Phase 4 Intravenous sedation using propofol;Intravenous sedation with midazolam
11 Growth Hormone and Brain Functioning After Traumatic Brain Injury Unknown status NCT01699308 Phase 4 Genotropin (somatropin)
12 The CAPTAIN Trial: Cerebrolysin Asian Pacific Trial in Acute Brain Injury and Neurorecovery Unknown status NCT01606111 Phase 4 Cerebrolysin;0.9% NaCl, saline
13 Effect of Rozerem on Sleep Among People With Traumatic Brain Injury Unknown status NCT01207050 Phase 4 Ramelteon
14 The Effect of Dexmedetomidine to Cognition of Geriatrics in Prolonged Surgery Unknown status NCT02123355 Phase 4 Induction of anesthesia;Sevoflurane, remifentanil ,vecuronium;Dexmedetomidine;Placebo
15 Treatment of Intracranial Hypertension of Severe Tramatic Brain Injured Patients. Physiopathologic Effects of Neuromuscular Blocking Agents Unknown status NCT02404779 Phase 4 cisatracurium besilate
16 Amantadine for Treatment of Symptoms of the Post-Traumatic Confusional State Unknown status NCT00693121 Phase 4 Amantadine hydrochloride;Placebo capsule
17 Intensive Insulin Therapy for Strict Glycemic Control in Neurosurgical Patients: Safety and Efficacy Unknown status NCT00505505 Phase 4 Insulin (Actrapid)
18 Normothermia in Patients With Acute Cerebral Damage Unknown status NCT00491192 Phase 4 Diclofenac
19 Is Sensory Stimulation Effective in Reducing Time Spent in a Coma or Vegetative State Unknown status NCT00163878 Phase 4
20 Antidepressant Maintenance in Traumatic Brain Injury Unknown status NCT00162916 Phase 4 citalopram;Placebo
21 Enteral Glutamine in Neurologically-injured Patients Completed NCT00204971 Phase 4
22 Glutamine Popsicles in Bone Marrow Transplant (BMT)/Hematopoietic Stem Cell Transplant (HSCT) Patients Completed NCT00204958 Phase 4 nutritional supplement;glutamine popsicle
23 Depression and Traumatic Brain Injury Completed NCT00254007 Phase 4 citalopram (celexa)
24 An Extension Study Evaluating the Efficacy and Safety of Rivastigmine in Patients With Traumatic Brain Injury (TBI) With Persistent Cognitive Deficits Completed NCT00219245 Phase 4 Rivastigmine
25 NIMI-NICU: Non Invasive Monitoring of the Intracranial Pressure - NeuroIntensive Care Unit Completed NCT01685476 Phase 4
26 Using Propranolol in Traumatic Brain Injury to Reduce Sympathetic Storm Phenomenon Completed NCT03401515 Phase 4 Propranolol Hydrochloride 1 MG/ML
27 The Study of Cognitive Rehabilitation Effectiveness for Mild Traumatic Brain Injury Completed NCT01339806 Phase 4
28 Intravenous Exenatide in Patients With Acute Brain Injury Completed NCT02058940 Phase 4 Exenatide
29 The Relationship Between Traumatic Brain Injury and Dopamine (a Chemical in the Brain) Completed NCT02015949 Phase 4 Methylphenidate;Placebo
30 Neuroendocrine Dysfunction in Traumatic Brain Injury: Effects of Testosterone Therapy Completed NCT01201863 Phase 4 Androgel (Testosterone Gel);Androgel Placebo
31 Pediatric Traumatic Brain Injury: Methylphenidate Effects on Early Recovery Completed NCT00035139 Phase 4 methylphenidate
32 Optimized Therapy in Severe Traumatic Brain Injured Patients Completed NCT02130674 Phase 4 Dipeptiven
33 Spinal Clearance Study: Expediting the Spinal Clearance Process in the Major Trauma Patient Completed NCT00163826 Phase 4
34 Pharmacological Intervention in Depression After Traumatic Brain Injury Completed NCT00205491 Phase 4 Venlafaxine
35 Myobloc Atrophy Study Completed NCT02052024 Phase 4 Botox;MYOBLOC
36 Effect of IV Acetaminophen on Patients in the Neurocritical Care Unit Completed NCT01948505 Phase 4 Intravenous acetaminophen;Placebo for IV acetaminophen
37 Safety, Tolerability and Effectiveness of Nuedexta in the Treatment of Pseudobulbar Affect (PBA) Completed NCT01799941 Phase 4 Nuedexta (DM 20 mg/Q 10 mg)
38 Topiramate Treatment of Hazardous and Harmful Alcohol Use in Veterans With TBI Completed NCT01750268 Phase 4 Topiramate;Placebo
39 Comparison of Three Botulinum Neuromodulators for Management of Facial Synkinesis Completed NCT03048383 Phase 4 OnabotulinumtoxinA Injectable Product;AbobotulinumtoxinA Injectable Product;Incobotulinumtoxin A Injectable Product
40 Anterior Pituitary Hormone Replacement in Traumatic Brain Injury Completed NCT00957671 Phase 4 Human Growth Hormone;Placebo
41 MRI and Neurodevelopment in Preterm Infants Following Administration of High-Dose Caffeine Completed NCT00809055 Phase 4 Caffeine citrate
42 Assess Safety and Efficacy of Levetiracetam(LEV;Keppra)for Seizure Prevention Completed NCT00618436 Phase 4 Levetiracetam;Phenytoin
43 Study of Ocular Penetration of Topically Administered Fluoroquinolones Completed NCT00924729 Phase 4 Moxifloxacin 0.5% ophthalmic solution;Besifloxacin 0.6% ophthalmic suspension
44 Comparative Efficacy of Three Preparations of Botox-A in Treating Spasticity Completed NCT00178646 Phase 4 Botox
45 The Use of Low Molecular Weight Heparin in Traumatic Brain Injury Completed NCT00170378 Phase 4 Enoxaparin
46 Beta Blockade in in Traumatic Brain Injury Recruiting NCT02957331 Phase 4 Propranolol
47 Effect of Amantadine Administration on Spatial Functioning Following Traumatic Brain Injury Recruiting NCT02321761 Phase 4 Amantadine hydrochloride
48 The Paediatric EVICEL® Neuro Study Recruiting NCT02309645 Phase 4
49 Timing of VTE Prophylaxis in TBI Recruiting NCT03081169 Phase 4 Enoxaparin Sodium 150 MG/ML Prefilled Syringe;Heparin
50 Does Short-Term Anti-Seizure Prophylaxis After Traumatic Brain Injury Decrease Seizure Rates? Recruiting NCT03054285 Phase 4 Levetiracetam

Search NIH Clinical Center for Head Injury

Genetic Tests for Head Injury

Anatomical Context for Head Injury

MalaCards organs/tissues related to Head Injury:

38
Brain, Eye, Testes, Bone, Heart, Spinal Cord, Bone Marrow

Publications for Head Injury

Articles related to Head Injury:

(show top 50) (show all 850)
# Title Authors Year
1
Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model. ( 29360998 )
2018
2
Bilateral medial rectus palsy due to midbrain infarction following concussion head injury. ( 29283153 )
2018
3
Pediatric dural venous sinus thrombosis following closed head injury: an easily overlooked diagnosis with devastating consequences. ( 29350373 )
2018
4
A Novel Approach to Assessing Head Injury Severity in Pediatric Patient Falls. ( 29277473 )
2018
5
Survival analysis-based human head injury risk curves: focus on skull fracture. ( 29409390 )
2018
6
Italian guidelines on the assessment and management of pediatric head injury in the emergency department. ( 29334996 )
2018
7
The Epidemiology of Pediatric Head Injury Treated Outside of Hospital Emergency Departments. ( 29240568 )
2018
8
Does Red Cell Distribution Width Predict Outcome in Traumatic Brain Injury: Comparison to Corticosteroid Randomization After Significant Head Injury. ( 29238428 )
2018
9
Pediatric Nonmissile Penetrating Head Injury: Case Series and Literature Review. ( 29155117 )
2018
10
Delayed hemiparkinsonism after closed head injury. ( 29364398 )
2018
11
Induced neural stem cell-derived astrocytes modulate complement activation and mediate neuroprotection following closed head injury. ( 29367701 )
2018
12
Headache following head injury: a population-based longitudinal cohort study (HUNT). ( 29356960 )
2018
13
Implementation of the Canadian CT Head Rule and Its Association With Use of Computed Tomography Among Patients With Head Injury. ( 28739290 )
2017
14
Pediatric head injury-an opportunity to make a difference in the global burden of disease. ( 28879383 )
2017
15
Critical Evaluation of the Lund Concept for Treatment of Severe Traumatic Head Injury, 25a88Years after Its Introduction. ( 28725211 )
2017
16
Head injury decision rules in children. ( 28952448 )
2017
17
Head injury decision rules in children - Authors' reply. ( 28952450 )
2017
18
TiO2-Nanowired Delivery of DL-3-n-butylphthalide (DL-NBP) Attenuates Blood-Brain Barrier Disruption, Brain Edema Formation, and Neuronal Damages Following Concussive Head Injury. ( 28856586 )
2017
19
Not every trauma patient with a radiographic head injury requires transfer for neurosurgical evaluation: Application of the brain injury guidelines to patients transferred to a level 1 trauma center. ( 28939250 )
2017
20
Letter to the Editor concerning "One and a half syndrome following penetrating head injury: Case report" by Mathew R. Voisin, Sanskriti Sasikumar, Jeremy H. Russell, Gelareh Zadeh, Journal of Clinical Neuroscience 41 (2017) 88-90. ( 28888479 )
2017
21
Epidemiology and Risk Factors for Bicycle-Related Severe Head Injury: A Single Center Experience. ( 29201840 )
2017
22
Risk of post-traumatic epilepsy after severe head injury in patients with at least one seizure. ( 28919762 )
2017
23
Paediatric mild head injury: is routine admission to a tertiary trauma hospital necessary? ( 28922710 )
2017
24
A Comprehensive Approach to Motorcycle-Related Head Injury Prevention: Experiences from the Field in Vietnam, Cambodia, and Uganda. ( 29189764 )
2017
25
Independent impact of plasma homocysteine levels on neurological outcome following head injury. ( 28741220 )
2017
26
Head injury patterns in helmeted and non-helmeted cyclists admitted to a London Major Trauma Centre with serious head injury. ( 28945822 )
2017
27
Clinical characteristics and prognosis of traumatic head injury following road traffic accidents admitted in ICU "analysis of 694 cases". ( 29234838 )
2017
28
Concurrent Surgery of Craniectomy and Splenectomy as Initial Treatment in Severe Traumatic Head Injury: A Case Report. ( 29201849 )
2017
29
Internal Carotid Artery Fibromuscular Dysplasia in a Child: Incidental Postmortem Finding after Head Injury. ( 28042220 )
2017
30
Computed tomography findings in young children with minor head injury presenting to the emergency department greater than 24h post injury. ( 28923560 )
2017
31
Clinical Factors Predictive for Intracranial Hemorrhage in Mild Head Injury. ( 29359046 )
2017
32
Head CT for Minor Head Injury Presenting to the Emergency Department in the Era of Choosing Wisely. ( 28874933 )
2017
33
Head injury decision rules in children. ( 28952449 )
2017
34
Unintentional Head Injury in Children Less than 3 Years of Age: An Insight into Safety Practices in a Developing Country. ( 28848117 )
2017
35
Recognizing malleus fracture in a woman with a head injury after a fall. ( 28846798 )
2017
36
A Case of Lenticulostriate Stroke Due to Minor Closed Head Injury in a 2-Year-Old Child: Role of Mineralizing Angiopathy. ( 28816772 )
2017
37
Head injury while on anticoagulation: Small numbers, big risks. ( 29185531 )
2017
38
Clinical Epidemiology of Head Injury from Road-Traffic Trauma in a Developing Country in the Current Era. ( 29326652 )
2017
39
Neurotrophy and immunomodulation of induced neural stem cell grafts in a mouse model of closed head injury. ( 28743043 )
2017
40
The effect of helmet materials and simulated bone and tissue layers on bullet behaviour in a gelatine model of overmatch penetrating head injury. ( 28815306 )
2017
41
Predictors of long-term neurological outcomes in non-accidental head injury. ( 29219962 )
2017
42
Globus pallidus internus deep brain stimulation for traumatic hemidystonia following penetrating head injury. ( 27184900 )
2016
43
Field Marshal Erwin Rommel: the head injury that may have prolonged the Second World War. ( 27364261 )
2016
44
Concussive head injury in children and adolescents. ( 27610428 )
2016
45
An Experimental Animal Model of Photodynamic Optic Nerve Head Injury (PONHI). ( 27158920 )
2016
46
Head injury and anisocoria on a cruise ship. ( 27681215 )
2016
47
Selecting children for head CT following head injury. ( 27449674 )
2016
48
Neurological findings in pediatric penetrating head injury at a university teaching hospital in Durban, South Africa: a 23-year retrospective study. ( 27472666 )
2016
49
Influence of two anesthetic techniques on blood sugar level in head injury patients: A comparative study. ( 27212748 )
2016
50
Head injury assessment of non-lethal projectile impacts: A combined experimental/computational method. ( 27614673 )
2016

Variations for Head Injury

Expression for Head Injury

Search GEO for disease gene expression data for Head Injury.

Pathways for Head Injury

Pathways related to Head Injury according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.46 APOE ENO2 S100B SOD1

GO Terms for Head Injury

Cellular components related to Head Injury according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.55 APOE ENO2 S100B SOD1 THBD
2 myelin sheath GO:0043209 9.13 BCL2 ENO2 SOD1
3 neuronal cell body GO:0043025 8.92 APOE ENO2 S100B SOD1

Biological processes related to Head Injury according to GeneCards Suite gene sharing:

(show all 17)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of neuron apoptotic process GO:0043524 9.61 APOE BCL2 SOD1
2 response to hydrogen peroxide GO:0042542 9.57 BCL2 SOD1
3 thymus development GO:0048538 9.56 BCL2 SOD1
4 ovarian follicle development GO:0001541 9.55 BCL2 SOD1
5 reactive oxygen species metabolic process GO:0072593 9.54 BCL2 SOD1
6 response to oxidative stress GO:0006979 9.54 APOE BCL2 SOD1
7 negative regulation of endothelial cell proliferation GO:0001937 9.52 APOE PRL
8 regulation of mitochondrial membrane potential GO:0051881 9.51 BCL2 SOD1
9 cell aging GO:0007569 9.49 BCL2 SOD1
10 regulation of multicellular organism growth GO:0040014 9.48 PRL SOD1
11 regulation of neuronal synaptic plasticity GO:0048168 9.46 APOE S100B
12 negative regulation of blood coagulation GO:0030195 9.4 APOE THBD
13 female pregnancy GO:0007565 9.33 BCL2 PRL THBD
14 response to reactive oxygen species GO:0000302 9.32 APOE SOD1
15 negative regulation of platelet activation GO:0010544 9.26 APOE THBD
16 positive regulation of catalytic activity GO:0043085 9.13 APOE BCL2 SOD1
17 negative regulation of cholesterol biosynthetic process GO:0045541 8.62 APOE SOD1

Molecular functions related to Head Injury according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein homodimerization activity GO:0042803 9.46 APOE BCL2 S100B SOD1
2 antioxidant activity GO:0016209 8.96 APOE SOD1
3 tau protein binding GO:0048156 8.62 APOE S100B

Sources for Head Injury

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
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29 HGMD
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31 HPO
32 ICD10
33 ICD10 via Orphanet
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35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
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54 OMIM via Orphanet
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60 QIAGEN
65 SNOMED-CT via HPO
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70 UMLS via Orphanet
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