MCID: HRT032
MIFTS: 75

Heart Disease

Categories: Cardiovascular diseases, Genetic diseases

Aliases & Classifications for Heart Disease

MalaCards integrated aliases for Heart Disease:

Name: Heart Disease 12 29 3 14
Congenital Heart Disease 12 29 52 14 69
Congenital Heart Defects 12 29 41 3
Heart Diseases 52 41 42 69
Heart Failure 52 41 69
Congenital Anomaly of Heart 12
Heart Defects, Congenital 42
Congestive Heart Failure 69
Heart Defects Congenital 52
Congenital Heart Defect 12
Heart-Congenital Defect 12
Heart Malformation 12
Heart Defect 12

Classifications:



Summaries for Heart Disease

MedlinePlus : 41 if you're like most people, you think that heart disease is a problem for others. but heart disease is the number one killer in the u.s. it is also a major cause of disability. there are many different forms of heart disease. the most common cause of heart disease is narrowing or blockage of the coronary arteries, the blood vessels that supply blood to the heart itself. this is called coronary artery disease and happens slowly over time. it's the major reason people have heart attacks. other kinds of heart problems may happen to the valves in the heart, or the heart may not pump well and cause heart failure. some people are born with heart disease. you can help reduce your risk of heart disease by taking steps to control factors that put you at greater risk: control your blood pressure lower your cholesterol don't smoke get enough exercise nih: national heart, lung, and blood institute

MalaCards based summary : Heart Disease, also known as congenital heart disease, is related to jervell and lange-nielsen syndrome and sick sinus syndrome 1, and has symptoms including hypoplastic left heart, angina pectoris and chest pain. An important gene associated with Heart Disease is GATA4 (GATA Binding Protein 4), and among its related pathways/superpathways are Vascular smooth muscle contraction and Human Embryonic Stem Cell Pluripotency. The drugs Ranolazine and Iloprost have been mentioned in the context of this disorder. Affiliated tissues include heart, endothelial and testes, and related phenotypes are cardiovascular system and growth/size/body region

Disease Ontology : 12 A cardiovascular system disease that involves the heart.

CDC : 3 CDC VITAL SIGNS: PROGRESS HAS SLOWED IN PREVENTING STROKE DEATHSAccess new data and proven strategies to prevent and treat stroke.

Related Diseases for Heart Disease

Diseases in the Heart Disease family:

Congenital Heart Defects, Nonsyndromic, 2 Congenital Heart Defects, Multiple Types, 3
Congenital Heart Defects, Multiple Types, 4

Diseases related to Heart Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 858)
id Related Disease Score Top Affiliating Genes
1 jervell and lange-nielsen syndrome 33.1 KCNH2 RYR2 SCN5A
2 sick sinus syndrome 1 32.8 KCNH2 RYR2 SCN5A TNNT2
3 hypertension, essential 32.4 ACE ADRB1 EDN1 NPPA NPPB
4 myocardial infarction 32.4 ACE ADRB1 EDN1 GATA4 NPPA NPPB
5 short qt syndrome 1 32.3 KCNH2 RYR2 SCN5A
6 artery disease 31.7 MYH7 NKX2-5 NPPB ZIC3
7 endocardium disease 31.3 NPPB SCN5A
8 peripheral artery disease 31.3 ACE EDN1 NPPB TNNI3
9 second-degree atrioventricular block 31.1 GATA4 KCNH2 NKX2-5 NPPB SCN5A TBX5
10 atrial standstill, digenic 31.1 SCN5A TNNT2
11 cardiac conduction disease with or without dilated cardiomyopathy 31.0 KCNH2 SCN5A
12 ventricular tachycardia, catecholaminergic polymorphic, 1 31.0 ADRB1 KCNH2 MYH7 NPPB RYR2 SCN5A
13 myopia 30.8 ACE EDN1 NPPA
14 pyelonephritis 30.8 ACE EDN1 NPPB
15 aortopulmonary window 30.8 ACE ADRB1 EDN1
16 long qt syndrome 9 30.5 ACE MYH6 MYH7 NPPB PTPN11 TNNI3
17 conotruncal heart malformations 12.2
18 hypertensive heart disease 12.2
19 rheumatic heart disease 12.0
20 ischemic heart disease 12.0
21 critical congenital heart disease 12.0
22 testicular anomalies with or without congenital heart disease 11.9
23 coronary heart disease 5 11.9
24 coronary heart disease 6 11.9
25 coronary heart disease 7 11.9
26 kyphoscoliotic heart disease 11.9
27 chronic pulmonary heart disease 11.8
28 cleft-limb-heart malformation syndrome 11.8
29 cfc1-related conotruncal heart malformations 11.8
30 acute pulmonary heart disease 11.7
31 craniostenosis, sagittal, with congenital heart disease, mental deficiency, and mandibular ankylosis 11.7
32 coronary artery disease 11.7
33 coronary heart disease 3 11.7
34 hirschsprung disease polydactyly heart disease 11.7
35 coronary heart disease 9 11.7
36 isolated nonsyndromic congenital heart disease/defects 11.7
37 shoulder and thorax deformity congenital heart disease 11.7
38 coronary heart disease 8 11.7
39 microcephaly, congenital heart disease, unilateral renal agenesis, and hyposegmented lungs 11.7
40 coronary heart disease 2 11.7
41 coronary heart disease 4 11.7
42 craniofacial abnormalities, cataracts, congenital heart disease, sacral neural tube defects, and growth and developmental retardation 11.7
43 craniostenosis with congenital heart disease mental retardation 11.6
44 congenital heart disease, atrial septal defect 11.6
45 down syndrome-related congenital heart disease 11.6
46 short limbs abnormal face congenital heart disease 11.6
47 cleft palate heart disease polydactyly absent tibia 11.6
48 short stature valvular heart disease 11.6
49 kallmann syndrome-heart disease syndrome 11.6
50 microcephaly-seizures-intellectual disability-heart disease syndrome 11.6

Comorbidity relations with Heart Disease via Phenotypic Disease Network (PDN): (show top 50) (show all 319)


3-Hydroxyacyl-Coa Dehydrogenase Deficiency Accessory Nerve Disease
Acquired Polycythemia Acquired Thrombocytopenia
Active Peptic Ulcer Disease Acute Anterolateral Myocardial Infarction
Acute Apical Periodontitis Acute Conjunctivitis
Acute Cor Pulmonale Acute Cystitis
Acute Inferolateral Myocardial Infarction Acute Kidney Failure
Acute Maxillary Sinusitis Acute Myocardial Infarction
Acute Myocarditis Acute Pancreatitis
Adjustment Disorder Alcoholic Cardiomyopathy
Alcoholic Liver Cirrhosis Allergic Urticaria
Alzheimer Disease Amyloidosis
Anthracosis Anxiety Disorder
Aortic Aneurysm Aortic Atherosclerosis
Aortic Valve Disease 2 Aortic Valve Insufficiency
Aplastic Anemia Asbestosis
Aspergillosis Asthma
Asthma Susceptibility, Phf11-Related Atrioventricular Block
Atrophic Gastritis Autoimmune Hemolytic Anemia
Bacteremia Balanoposthitis
Basilar Artery Insufficiency Benign Essential Hypertension
Benign Hypertensive Renal Disease Benign Renovascular Hypertension
Bleeding Disorder, Platelet-Type, 11 Blepharitis
Blepharoconjunctivitis Blood Platelet Disease
Bronchiectasis Bronchitis
Bronchopneumonia Budd-Chiari Syndrome

Graphical network of the top 20 diseases related to Heart Disease:



Diseases related to Heart Disease

Symptoms & Phenotypes for Heart Disease

Human phenotypes related to Heart Disease:

32
id Description HPO Frequency HPO Source Accession
1 hypoplastic left heart 32 HP:0004383

UMLS symptoms related to Heart Disease:


angina pectoris, chest pain, edema, tremor, equilibration disorder, syncope

MGI Mouse Phenotypes related to Heart Disease:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.41 ACE ADRB1 ANKRD1 EDN1 GATA4 KCNH2
2 growth/size/body region MP:0005378 10.25 ABL1 ACE ADRB1 ANKRD1 EDN1 GATA4
3 homeostasis/metabolism MP:0005376 10.21 ABL1 ACE ADRB1 ANKRD1 EDN1 GATA4
4 mortality/aging MP:0010768 10.2 EDN1 GATA4 KCNH2 MYH6 NKX2-5 PTPN11
5 embryo MP:0005380 10.17 ABL1 EDN1 GATA4 KCNH2 NKX2-5 PTPN11
6 muscle MP:0005369 10.16 ABL1 ADRB1 ANKRD1 EDN1 GATA4 KCNH2
7 no phenotypic analysis MP:0003012 9.7 MYH7 NKX2-5 PTPN11 RYR2 ADRB1 ANKRD1
8 normal MP:0002873 9.7 ABL1 ANKRD1 EDN1 GATA4 NKX2-5 PTPN11
9 respiratory system MP:0005388 9.1 ABL1 GATA4 NKX2-5 PTPN11 TNNI3 ZIC3

Drugs & Therapeutics for Heart Disease

Drugs for Heart Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 1157)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ranolazine Approved, Investigational Phase 4,Phase 3,Phase 2 142387-99-3, 95635-55-5 56959
2
Iloprost Approved, Investigational Phase 4,Phase 3,Phase 2 78919-13-8 6443959
3
Aspirin Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 50-78-2 2244
4
Cilostazol Approved Phase 4,Phase 3 73963-72-1 2754
5
Everolimus Approved Phase 4,Phase 3,Phase 2,Phase 1 159351-69-6 6442177
6
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
7
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 53123-88-9 5284616 6436030 46835353
8
Ticlopidine Approved Phase 4,Phase 2,Phase 3,Phase 1 55142-85-3 5472
9
Fluvastatin Approved Phase 4,Phase 3,Phase 2 93957-54-1 1548972
10
Carvedilol Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 72956-09-3 2585
11
Clonidine Approved Phase 4,Phase 2 4205-90-7 2803
12
Dobutamine Approved Phase 4,Phase 3,Phase 2,Phase 1 34368-04-2 36811
13
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 33069-62-4 36314
14
Ticagrelor Approved Phase 4,Phase 3,Phase 2,Phase 1 274693-27-5 9871419
15
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 9005-49-6 772 46507594
16
Nicorandil Approved Phase 4 65141-46-0 47528
17
Acarbose Approved, Investigational Phase 4,Phase 3 56180-94-0 441184
18
Valsartan Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 137862-53-4 60846
19
Verapamil Approved Phase 4,Phase 3,Phase 2 52-53-9 2520
20
Metformin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 657-24-9 14219 4091
21
Pioglitazone Approved, Investigational Phase 4,Phase 3,Phase 2 111025-46-8 4829
22
Zinc Approved Phase 4,Phase 3,Phase 2,Phase 1 7440-66-6 32051 23994
23
Amiodarone Approved, Investigational Phase 4,Phase 3,Phase 2 1951-25-3 2157
24
Benzocaine Approved Phase 4,Phase 3,Phase 2,Phase 1 1994-09-7, 94-09-7 2337
25
Menthol Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 2216-51-5 16666
26
Chromium Approved Phase 4,Phase 3,Phase 2,Phase 1 7440-47-3 27668
27
Esomeprazole Approved, Investigational Phase 4,Phase 2 161796-78-7, 119141-88-7 4594 9579578
28
Pantoprazole Approved Phase 4,Phase 3,Phase 1 102625-70-7 4679
29
Rabeprazole Approved, Investigational Phase 4 117976-89-3 5029
30
Citalopram Approved Phase 4 59729-33-8 2771
31
Ezetimibe Approved Phase 4,Phase 3,Phase 2,Phase 1 163222-33-1 150311
32
Irbesartan Approved, Investigational Phase 4,Phase 2,Phase 3 138402-11-6 3749
33
Ramipril Approved Phase 4,Phase 3,Phase 2 87333-19-5 5362129
34
Amlodipine Approved Phase 4,Phase 3,Phase 2,Phase 1 88150-42-9 2162
35
Hydrochlorothiazide Approved, Vet_approved Phase 4,Phase 3,Phase 2 58-93-5 3639
36
Cyproterone Acetate Approved, Investigational Phase 4 427-51-0
37
Ethinyl Estradiol Approved Phase 4,Phase 1 57-63-6 5991
38
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 51-61-6, 62-31-7 681
39
Spironolactone Approved Phase 4,Phase 3,Phase 2,Phase 1 1952-01-7, 52-01-7 5833
40
Methyltestosterone Approved Phase 4,Phase 3,Phase 2 58-18-4 6010
41
Testosterone Approved, Investigational Phase 4,Phase 3,Phase 2 58-22-0 6013
42
Udenafil Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 268203-93-6 6918523
43
Zolpidem Approved Phase 4 82626-48-0 5732
44
Pravastatin Approved Phase 4,Phase 3,Phase 2,Phase 1 81093-37-0 54687
45
Enalapril Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 75847-73-3 5362032 40466924
46
Enalaprilat Approved Phase 4,Phase 3,Phase 2,Phase 1 76420-72-9 6917719
47
Metoprolol Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 37350-58-6, 51384-51-1 4171
48
Digoxin Approved Phase 4,Phase 3,Phase 2,Phase 1 20830-75-5 30322 2724385
49
Furosemide Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 54-31-9 3440
50
Metolazone Approved Phase 4,Phase 2,Phase 1 17560-51-9 4170

Interventional clinical trials:

(show top 50) (show all 10000)

id Name Status NCT ID Phase Drugs
1 Improved Diagnosis of Congenital Heart Disease by Magnetic Resonance Imaging Using Vasovist Unknown status NCT00668824 Phase 4 Vasovist
2 Danshen Dropping Pill for Coronary Heart Disease Heart and Artery Structure and Function Unknown status NCT01825759 Phase 4 danshen dripping pill
3 Ranolazine for Improving Symptoms of Palpitations Unknown status NCT01495520 Phase 4 Ranolazine;Placebo
4 Effects of Iloprost Treatment in Adult Patients With Pulmonary Arterial Hypertension Related to Congenital Heart Disease Unknown status NCT01383083 Phase 4
5 Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis - SAfety & EffectiveneSS of Drug-ElUting Stents & Anti-platelet REgimen Unknown status NCT01267734 Phase 4 Triple anti-platelet therapy (TAT);Double-dose clopidogrel anti-platelet therapy (DDAT)
6 Endothelial Dysfunction in Subjects With History of Premature Coronary Artery Disease Unknown status NCT00917527 Phase 4 Atorvastatin
7 Study to Investigate the Effect of Heart Rate Reduction With Ivabradine on Vascular Elastic Properties and Endothelial Function in Patients With Stable Coronary Heart Disease Unknown status NCT01768585 Phase 4 Ivabradine;Placebo
8 Fluvastatin AmelIorates aTHerosclerosis Study Unknown status NCT01681199 Phase 4 Fluvastatin extended release tablet
9 Trial to Assess the Everolimus-Eluting Coronary Stent System (PROMUS Element) for Coronary Revascularization Unknown status NCT01342822 Phase 4
10 Rosuvastatin Effect on Reducing Coronary Atherosclerosis Plaques Volume Unknown status NCT01382277 Phase 4 Rosuvastatin
11 Hemoderivative Imputable Complications in Initial Uncomplicated Heart Surgery Unknown status NCT01457586 Phase 4
12 Diagnostic Benefits of HyperQTM vs. Conventional ECG Stress Test. Comparison of HyperQ vs. Stress ECG in Women Before Angiography Unknown status NCT00850486 Phase 4
13 Ischemia In Hemodialysed Patients: Ivabradine Versus Carvedilol Unknown status NCT01425164 Phase 4 Ivabradine;Carvedilol
14 EPIC (Evaluating Perioperative Ischemia Reduction by Clonidine) Unknown status NCT00335582 Phase 4 clonidine hydrochloride
15 Study of Effects of Sildenafil on Patients With Fontan Heart Circulation Unknown status NCT01815502 Phase 4 Dobutamine
16 Comparison of Diabetes Mellitus and Non-diabetes Mellitus Patients for DES Surface COVERage by OCT Unknown status NCT01021930 Phase 4
17 Intracoronary Stenting and Antithrombotic Regimen: ADjusting Antiplatelet Treatment in PatienTs Based on Platelet Function Testing Unknown status NCT01456364 Phase 4 Ticagrelor;Prasugrel
18 Test Efficacy of Biodegradable and Permanent Limus-Eluting Stents Unknown status NCT01068106 Phase 4
19 Relation Among Shear Stress Distribution, Stent Design, and Subsequent Vessel Healing After Drug-eluting Stent Implantation (SHEAR DES) Unknown status NCT01942044 Phase 4
20 Test of Long-Term Safety and Efficacy of Sirolimus-Permanent-Polymer Eluting Stent (Cypher)- and Sirolimus-Polymer-free Eluting Stents (PPS/PFS) Assessed by Optical Coherence Tomography Unknown status NCT01260558 Phase 4
21 Test Safety and Efficacy of Zotarolimus- and Everolimus-Eluting Stents (ZES/EES) Assessed by Optical Coherence Tomography Unknown status NCT01230723 Phase 4
22 Effect of Nicorandil for the Patients of Acute ST Segment Elevation Myocardial Infarction Unknown status NCT02435797 Phase 4 Nicorandil;normal saline
23 Study of Endothelial Dysfunction in Systemic Lupus and Its Role in Heart Disease Unknown status NCT00188188 Phase 4 quinipril
24 Impact of Acarbose on Abnormal Glucose Regulation in Patients With Coronary Artery Disease (AAA Trial) Unknown status NCT00858676 Phase 4 acarbose
25 Enteral Nutrition After Cardiovascular Surgery Unknown status NCT01432769 Phase 4
26 The ABC Trial Does All-Blood Cardioplegia Prevent Blood Transfusion in Cardiac Surgery? A Single Centre Pilot Study Unknown status NCT01623193 Phase 4
27 Effect of Rosuvastatin Therapy on HDL2 Level Unknown status NCT02593487 Phase 4 Rosuvastatin 10mg/d group;Rosuvastatin 20mg/d group
28 Comparison of Biolimus A9 and Everolimus Drug-Eluting Stents in Patients With ST Segment Elevation Myocardial Infarction Unknown status NCT00888758 Phase 4
29 Revascularization in Heart Failure Trial – REHEAT 2 Unknown status NCT00388245 Phase 4
30 A Morbidity-Mortality and Remodeling Study With Valsartan Unknown status NCT00133328 Phase 4 valsartan
31 Effect of Ranolazine on Valvular Disease in Patients With Pacemakers Unknown status NCT01979965 Phase 4 Ranolazine (Active drug);Placebo
32 Carvedilol Versus Verapamil in Chronic Heart Failure Secondary to Non-Ischemic Cardiomyopathy Unknown status NCT00348530 Phase 4 Verapamil
33 Metformin in Postmenopausal Women With Metabolic Syndrome Unknown status NCT01342744 Phase 4 Metformin;Placebo
34 Effects of Atorvastatin Treatment on Left Ventricular Diastolic Function in Peritoneal Dialysis Patients Unknown status NCT01503671 Phase 4 Atorvastatin
35 Treatment of Coronary Atherosclerosis by Insulin Sensitizers in Insulin-Resistant Patients Unknown status NCT00155350 Phase 4 pioglitazone
36 Prevention of Contrast Nephropathy During Diagnostic Coronary Angiogram or PCI With Hydratation Based on LEVDP Unknown status NCT00584350 Phase 4
37 The Low HDL On Six Weeks Statin Therapy (LOW) Study Unknown status NCT00238004 Phase 4 Nicotinic acid
38 Therapy With Verapamil or Carvedilol in Chronic Heart Failure Unknown status NCT00374465 Phase 4 Verapamil;Carvedilol
39 Does Sildenafil Protect Against Pulmonary Related Complications Following Cardiopulmonary Bypass? Unknown status NCT00350441 Phase 4 Sildenafil Citrate
40 Rosuvastatin Effect on Telomere-telomerase System in ACS Unknown status NCT02299245 Phase 4 rosuvastatin
41 Scripps Evaluation of Antiplatelet Therapies for Intermediate Duration With the Endeavor Stent (Seaside) Unknown status NCT00963781 Phase 4 Reduced duration (6 months) DAPT
42 Cardiac Resynchronization in Atrial Fibrillation Trial - a Pilot Study Unknown status NCT01850277 Phase 4 Amiodarone;Pharmacotherapy to slow and control ventricular rate
43 Comparative Phase IV Study: Efficacy And Safety of TiTAN2 Versus COBALT-CHROME Stents- EVIDENCEII Unknown status NCT01918150 Phase 4
44 Evaluation of Antiplatelet Drug Resistance in Taiwanese With VASP & Platelet Mapping ™ Assay Unknown status NCT01023360 Phase 4 Clopidogrel and proton pump inhibitors
45 Major Depressive Disorder - Understanding The Link Between The Brain And The Heart Unknown status NCT01568307 Phase 4 Participants will be prescribed an approved selective serotonin re-uptake inhibitor (SSRI) antidepressant.
46 DECARD: Study of Escitalopram in the Prevention of Depression in Patients With Acute Coronary Syndrome Unknown status NCT00140257 Phase 4 Escitalopram
47 Cardiovascular Effects of Agomelatine and Escitalopram in Patients With Major Depressive Disorder (MDD) Unknown status NCT01483053 Phase 4 Agomelatine;Escitalopram
48 The Canadian Prevention of Renal and Cardiovascular Endpoints Trial Unknown status NCT00231803 Phase 4
49 Platelet Function With New Pediatric Oxygenator and Heparin and Non Heparin Coating in Pediatric Cardiac Surgery Unknown status NCT01648712 Phase 4
50 A Study Evaluating the Effects of Lipid Lowering Treatment on Steroid Synthesis Unknown status NCT00433823 Phase 4 Atorvastatin, Ezetimibe

Search NIH Clinical Center for Heart Disease

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: heart diseases

Genetic Tests for Heart Disease

Genetic tests related to Heart Disease:

id Genetic test Affiliating Genes
1 Congenital Heart Disease 29
2 Congenital Heart Defects 29
3 Heart Disease 29

Anatomical Context for Heart Disease

MalaCards organs/tissues related to Heart Disease:

39
Heart, Endothelial, Testes, Kidney, Lung, Bone, Brain

Publications for Heart Disease

Articles related to Heart Disease:

(show top 50) (show all 5323)
id Title Authors Year
1
Response to the letter to the editor regarding "Smoking and coronary heart disease in patients with type 2 diabetes mellitus". ( 28951340 )
2017
2
Exploratory study into awareness of heart disease and health care seeking behavior among Emirati women (UAE) - Cross sectional descriptive study. ( 28950842 )
2017
3
Comparison of Pulmonary Venous and Left Atrial Remodeling in Patients With Atrial Fibrillation With Hypertrophic Cardiomyopathy Versus With Hypertensive Heart Disease. ( 28214001 )
2017
4
The landscape of congenital heart disease. ( 28529923 )
2017
5
Autoimmune myocarditis in systemic sclerosis: an unusual form of scleroderma heart disease presentation. ( 28772040 )
2017
6
Association of dietary cholesterol and egg intakes with the risk of incident dementia or Alzheimer disease: the Kuopio Ischaemic Heart Disease Risk Factor Study. ( 28052883 )
2017
7
Global, Regional, and National Burden of Rheumatic Heart Disease, 1990-2015. ( 28834488 )
2017
8
Associations of GATA4 genetic mutations with the risk of congenital heart disease: A meta-analysis. ( 28471988 )
2017
9
Quality of life: an underutilized patient-reported outcome for adults with congenital heart disease. ( 28523142 )
2017
10
Traditional Cardiovascular Risk Factors and Their Relation to Future Surgery for Valvular Heart Disease or Ascending Aortic Disease: AA Case-Referent Study. ( 28476875 )
2017
11
Small airway dysfunction in smokers with stable ischemic heart disease. ( 28846677 )
2017
12
Increased Hazard of Myocardial Infarction With Insulin-Provision Therapy in Actively Smoking Patients With Diabetes Mellitus and Stable Ischemic Heart Disease: The BARI 2D (Bypass Angioplasty Revascularization Investigation 2 Diabetes) Trial. ( 28903941 )
2017
13
Thyroid function and ischemic heart disease: a Mendelian randomization study. ( 28819171 )
2017
14
Relaxation and the Role of Calcium in Isolated Contracting Myocardium From Patients With Hypertensive Heart Disease and Heart Failure With Preserved Ejection Fraction. ( 28784688 )
2017
15
Regression of Established Cardiac Fibrosis in Hypertensive Heart Disease. ( 28379281 )
2017
16
Rheumatic heart disease in a developing country: Incidence and trend (Monastir; Tunisia: 2000-2013). ( 27883972 )
2017
17
Analysis of Screening Electrocardiogram for the Subcutaneous Defibrillator in Adults with Congenital Heart Disease. ( 28534239 )
2017
18
Genotype Positive Long QT Syndrome in Patients With Coexisting Congenital Heart Disease. ( 28532774 )
2017
19
Should New Zealand introduce nationwide pulse oximetry screening for the detection of critical congenital heart disease in newborn infants? ( 28081558 )
2017
20
Pulmonary vascular disease due to left heart disease: how to achieve a more accurate approach beyond the haemodynamic phenotype. ( 28949088 )
2017
21
Residents' understanding of adult congenital heart disease. ( 28092429 )
2017
22
NYHA classification in adults with congenital heart disease: Relation to objective measures of exercise and outcome. ( 28950356 )
2017
23
Retinovascular findings in newborns with critical congenital heart disease: A case series. ( 28504505 )
2017
24
Smoking and coronary heart disease in patients with type 2 diabetes mellitus. ( 28951339 )
2017
25
Preschool Neurodevelopmental Outcomes in Children with Congenital Heart Disease. ( 28081891 )
2017
26
Screening for rheumatic heart disease: is a paradigm shift required? ( 28864463 )
2017
27
LipoproteinA (a) and coronary heart disease - is there an efficient secondary prevention? ( 28233270 )
2017
28
Hypermethylation of brain natriuretic peptide gene is associated with the risk of rheumatic heart disease. ( 27920275 )
2017
29
Modified mRNA as a therapeutic tool to induce cardiac regeneration in ischemic heart disease. ( 27911047 )
2017
30
A Genetic Variant in FIGN Gene Reduces the Risk of Congenital Heart Disease in Han Chinese Populations. ( 28534241 )
2017
31
Estimation of Antioxidant Levels in Saliva and Serum of Chronic Periodontitis Patients with and without Ischemic Heart Disease. ( 28781595 )
2017
32
Transfer of Neonates with Critical Congenital Heart Disease Within a Regionalized Network. ( 28711963 )
2017
33
Prenatal Diagnosis of Dextrocardia with Complex Congenital Heart Disease Using Fetal Intelligent Navigation Echocardiography (FINE) and a Literature Review. ( 28641300 )
2017
34
Six-Year Outcome of Subjects Without Overt Heart Disease With an Early Repolarization/J Wave Electrocardiographic Pattern. ( 28947311 )
2017
35
Acquired coronary artery disease in adult patients with congenital heart disease: a true or a false problem? ( 28072626 )
2017
36
Tumor necrosis factor-alpha gene polymorphisms and susceptibility to ischemic heart disease: A systematic review and meta-analysis. ( 28383437 )
2017
37
Decreased frequencies and impaired functions of the CD31(+) subpopulation in Treg cells associated with decreased FoxP3 expression and enhanced Treg cell defects in patients with coronary heart disease. ( 27997991 )
2017
38
A National Call to Action-Improving the Detection of Critical Congenital Heart Disease. ( 28129863 )
2017
39
Myofilament remodeling and function is more impaired in peripartum cardiomyopathy compared to dilated cardiomyopathy and ischemic heart disease. ( 28935576 )
2017
40
Critical congenital heart disease screening with a pulse oximetry in neonates. ( 28672762 )
2017
41
Management of pulmonary hypertension from left heart disease in candidates for orthotopic heart transplantation. ( 28932571 )
2017
42
Rheumatic heart disease in paediatric critical care retrieval. ( 28070958 )
2017
43
Influence of SCARB1 gene SNPs on serum lipid levels and susceptibility to coronary heart disease and cerebral infarction in a Chinese population. ( 28552715 )
2017
44
Self-Rated Health Status and Risk of Ischemic Heart Disease in the China Kadoorie Biobank Study: A Population-Based Cohort Study. ( 28939702 )
2017
45
Fragmented QRS: A marker of hypertensive heart disease? ( 28721702 )
2017
46
Congenital heart disease and cardiac procedural outcomes in patients with trisomy 21 and Turner syndrome. ( 28736822 )
2017
47
Genetic polymorphism of methylenetetrahydrofolate reductase as a potential risk factor for congenital heart disease: A meta-analysis in Chinese pediatric population. ( 28591039 )
2017
48
Long term gluten consumption in adults without celiac disease and risk of coronary heart disease: prospective cohort study. ( 28465308 )
2017
49
Selective Pressure-Regulated Retroinfusion for Gene Therapy Application in Ischemic Heart Disease. ( 27910055 )
2017
50
The Effects of Age, Period, and Cohort on Mortality from Ischemic Heart Disease in China. ( 28067846 )
2017