MCID: HRT011
MIFTS: 41

Heart Septal Defect malady

Category: Cardiovascular diseases

Aliases & Classifications for Heart Septal Defect

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Aliases & Descriptions for Heart Septal Defect:

Name: Heart Septal Defect 11 13
Heart Septal Defects 38 67
Septal Defect 11 49
 
Congenital Septal Defect of Heart 11
Cardiac Septal Defects 11
Septal Defect Nos 11

Classifications:



External Ids:

Disease Ontology11 DOID:1681
ICD1029 Q21, Q21.9
MeSH38 D006343
NCIt44 C84482

Summaries for Heart Septal Defect

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Wikipedia:70 Heart septal defect refers to a congenital heart defect of one of the septa of the heart. more...

MalaCards based summary: Heart Septal Defect, also known as heart septal defects, is related to atrial heart septal defect and lymphedema, cardiac septal defects, and characteristic facies, and has symptoms including cardiac dyskinesia An important gene associated with Heart Septal Defect is NKX2-5 (NK2 Homeobox 5), and among its related pathways are HOP Signaling and SRF and miRs in Smooth Muscle Differentiation and Proliferation. Affiliated tissues include heart and brain, and related mouse phenotypes are limbs/digits/tail and craniofacial.

Related Diseases for Heart Septal Defect

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Diseases related to Heart Septal Defect via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 52)
idRelated DiseaseScoreTop Affiliating Genes
1atrial heart septal defect12.3
2lymphedema, cardiac septal defects, and characteristic facies12.1
3severe hypotonia-psychomotor developmental delay-strabismus-cardiac septal defect syndrome12.0
4ventricular septal defect11.6
5atrial septal defect 611.5
6atrial septal defect 111.5
7atrial septal defect 7, with or without av conduction defects11.5
8atrial septal defect 811.5
9atrial septal defect 411.5
10atrial septal defect 211.5
11atrial septal defect 311.5
12atrial septal defect 511.5
13atrial septal defect 911.5
14hyperphosphatasia with mental retardation syndrome 211.0
15mitral regurgitation, conductive deafness, and fusion of cervical vertebrae and of carpal and tarsal bones10.9
16atrioventricular septal defect10.8
17univentricular heart with single atrio-ventricular valve10.6CRELD1, GATA4
18azygos continuation of the inferior vena cava10.6CRELD1, GATA4
19undifferentiated carcinoma of the corpus uteri10.5CFC1, GDF1
20second-degree atrioventricular block10.4GATA4, NKX2-5, TBX5
21drug-induced vasculitis10.4GATA4, ZFPM2
22d-glycericacidemia10.4CITED2, NODAL
23suppurative cholangitis10.4GDF1, NKX2-6
24straddling and/or overriding mitral valve10.4CRELD1, GATA4, GATA6
25partial duplication of the short arm of chromosome x10.4CRELD1, GATA4, GATA6
266-phosphogluconate dehydrogenase deficiency10.3CITED2, GATA4, NKX2-5, NKX2-6
27joubert syndrome 1310.3NKX2-5, TBX1, TBX5
28cervical adenoid basal carcinoma10.3CRELD1, GATA4, NKX2-6, TBX5
29stork bite10.3CRELD1, NODAL
30pituitary adenoma10.2GATA4, GATA6, ZFPM2
31macroglossia10.1CRELD1, GATA4, GDF1, NKX2-5, NKX2-6
32trophoblastic neoplasm10.1ACVRL1, CRELD1
33adams-oliver syndrome 510.1CRELD1, NKX2-6, TNNI3
34pancreatic serous cystadenocarcinoma10.1CRELD1, GATA4, GATA6, NKX2-6, TBX5
35holt-oram syndrome10.0TBX1, TBX5
36ceroid lipofuscinosis, neuronal, 610.0CRELD1, NKX2-6, TBX5, TNNI3
37cataract 17, multiple types10.0GDF1, NKX2-6, TBX1
38childhood parosteal osteogenic sarcoma9.9CRELD1, NKX2-6, NODAL, TNNI3
39pericardium disease9.8ACVRL1, CRELD1, GATA6, GDF1, NKX2-6
40pyelonephritis9.8CFC1, GATA4, NKX2-5, NKX2-6, TNNI3
41fetal alcohol syndrome9.7CRELD1, GATA4, GATA6, GDF1, NKX2-5, NKX2-6
42heart disease9.7
43floating-harbor syndrome9.6
44microcephaly9.6
45photokeratitis9.4CITED2, CLNK, GATA4, GATA6, NKX2-5, NKX2-6
46melanotic neuroectodermal tumor9.3CITED2, GATA4, GATA6, GDF1, NKX2-5, NKX2-6
47dhdds-cdg9.2CFC1, CRELD1, GATA4, GATA6, GDF1, NKX2-5
48viral hepatitis9.1ACVRL1, CLNK, CRELD1, GATA4, GDF1, NKX2-5
49slowed nerve conduction velocity, ad9.0CITED2, CRELD1, GATA4, GATA6, GDF1, NKX2-5
50neuroendocrine tumor8.4CFC1, CITED2, CRELD1, GATA4, GDF1, NKX2-5

Graphical network of the top 20 diseases related to Heart Septal Defect:



Diseases related to heart septal defect

Symptoms for Heart Septal Defect

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UMLS symptoms related to Heart Septal Defect:


cardiac dyskinesia

Drugs & Therapeutics for Heart Septal Defect

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Drugs for Heart Septal Defect (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 122)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
WarfarinapprovedPhase 4, Phase 2, Phase 345481-81-26691, 54678486
Synonyms:
(-)-Warfarin
(S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone
(S)-Warfarin
(phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarin
(phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarine
1-(4'-Hydroxy-3'-coumarinyl)-1-phenyl-3-butanone
200 Coumarin
200 coumarin
3-(1'-Phenyl-2'-acetylethyl)-4-hydroxycoumarin
3-(Acetonylbenzyl)-4-hydroxycoumarin
3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin
3-(alpha-Phenyl-beta-acetylaethyl)-4-hydroxycumarin
3-(alpha-Phenyl-beta-acetylethyl)-4-hydroxycoumarin
4-Hydroxy-3- (3-oxo-1-fenyl-butyl) cumarine
4-Hydroxy-3- (3-oxo-1-phenyl-butyl)-cumarin
4-Hydroxy-3-(3-oxo-1-fenyl-butyl) cumarine
4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-cumarin
4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one
4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one
4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin
4-Idrossi-3- (3-oxo-)-fenil-butil)-cumarine
4-Idrossi-3-(3-oxo-)-fenil-butil)-cumarine
4-Idrossi-3-(3-oxo-1-fenil-butil)-cumarine
45706_FLUKA
45706_RIEDEL
4oh-coumarin deriv.
5543-56-6
5543-57-7
81-81-2
A2250_FLUKA
A2250_SIGMA
AC-15978
AC1L1N37
AC1Q6AN3
AR-1E2310
Arab Rat Death
Arab rat death
Arab rat deth
Athrombin
Athrombin-K
Athrombin-k
Athrombine-K
Athrombine-k
BRD-A24514565-001-02-2
BRD-A24514565-236-01-6
BRN 1293536
BSPBio_002026
Bio-0586
Brumolin
C01541
C19H16O4
CBDivE_002127
CBDivE_013236
CBKinase1_000192
CBKinase1_012592
CHEBI:10033
CHEMBL1464
CID6691
CO-Rax
Caswell No. 903
Choice
Choice (TN)
Co-Rax
Co-rax
Compound 42
Coumadin
Coumadin Tabs
Coumafen
Coumafene
Coumafene [French]
Coumaphen
Coumaphene
Coumarins
Coumefene
Cov-R-Tox
Cov-R-tox
D-Con
D08682
DB00682
DL-3-(alpha-acetonylbenzyl)-4-hydroxycoumarin
Dethmor
Dethnel
Dicusat E
Dicusat e
DivK1c_000444
EINECS 201-377-6
EINECS 226-907-3
EPA Pesticide Chemical Code 086002
Eastern states duocide
Fasco fascrat powder
Frass-Ratron
Frass-ratron
HMS1921K07
HMS2092C20
HMS501G06
HSDB 1786
I14-0958
IDI1_000444
Jantoven
KBio1_000444
KBio2_000674
KBio2_003242
KBio2_005810
KBio3_001526
KBioGR_000901
KBioSS_000674
Killgerm sewarin p
Kumader
Kumadu
Kumatox
Kypfarin
LS-55083
Latka 42
Latka 42 [Czech]
Liqua-tox
MLS001304042
Maag Rattentod Cum
Maag rattentod cum
Mar-Frin
Mar-frin
Marevan
Martin'S mar-frin
Martin's mar-frin
 
Maveran
MolPort-001-787-822
Mouse pak
NCGC00094810-01
NCGC00094810-02
NCGC00159398-03
NCGC00178855-01
NINDS_000444
NSC 59813
NSC59813
PS104_SUPELCO
Panwarfin
Place-Pax
Place-pax
Prothromadin
RAX
RCR grey squirrel killer concentrate
RCRA waste no. P001
Rat & mice bait
Rat and mice bait
Rat-B-gon
Rat-Gard
Rat-Kill
Rat-Mix
Rat-O-cide #2
Rat-O-cide no. 2
Rat-Ola
Rat-Trol
Rat-a-way
Rat-alpha-way
Rat-b-gon
Rat-beta-gon
Rat-gard
Rat-kill
Rat-mix
Rat-o-cide #2
Rat-ola
Rat-trol
Ratorex
Ratox
Ratoxin
Ratron
Ratron G
Ratron g
Rats-no-more
Ratten-Koederrohr
Ratten-koederrohr
Rattenstreupulver Neu Schacht
Rattenstreupulver neu schacht
Rattenstreupulver new schacht
Rattentraenke
Rattunal
Rcra waste number P001
Ro-Deth
Ro-deth
Rodafarin
Rodafarin C
Rodafarin c
Rodex
Rodex blox
Rosex
Rough & ready mouse mix
Rough and ready mouse mix
SMP1_000316
SMR000718754
SPBio_000870
SPECTRUM1500613
STK364490
Sakarat
Sewarin
Sofarin
Solfarin
Sorexa Plus
Sorexa plus
Spectrum2_000935
Spectrum3_000583
Spectrum4_000381
Spectrum5_001751
Spectrum_000194
Spray-trol brand roden-trol
Temus W
Temus w
Tintorane
Tox-Hid
Tox-hid
Twin light rat away
UNII-5Q7ZVV76EI
Vampirinip II
Vampirinip III
Vampirinip iii
W.A.R.F. 42
WARF compound 42
WLN: T66 BOVJ DYR&1V1 EQ
Waran
Warf 10
Warf 42
Warfarat
Warfarin (INN)
Warfarin (and salts of)
Warfarin Plus
Warfarin Q
Warfarin [BSI:ISO]
Warfarin [INN:BAN]
Warfarin plus
Warfarin plus [discontinued]
Warfarin sodium
Warfarin titrated to an INR of 2.5-3.0
Warfarin(R)
Warfarina
Warfarina [INN-Spanish]
Warfarine
Warfarine [INN-French]
Warfarine [ISO-French]
Warfarinum
Warfarinum [INN-Latin]
Warficide
Warfilone
Zoocoumarin
Zoocoumarin [Netherlands and USSR]
Zoocoumarin [Russian]
delta-Con
nchembio.307-comp19
rac-Warfarin
warfarin
2
Aspirinapproved, vet_approvedPhase 4, Phase 2, Phase 3111250-78-22244
Synonyms:
11126-35-5
11126-37-7
1oxr
2-(ACETYLOXY)benzoic acid
2-(Acetyloxy)benzoate
2-(Acetyloxy)benzoic acid
2-Acetoxybenzenecarboxylic acid
2-Acetoxybenzoate
2-Acetoxybenzoic acid
2-Carboxyphenyl acetate
2349-94-2
26914-13-6
50-78-2
8-hour Bayer
98201-60-6
A 5376
A.S.A
A.S.A.
A.S.A. Empirin
A.S.A. empirin
A2093_SIGMA
A3160_SIGMA
A5376_SIGMA
A6810_SIGMA
AB1003266
AC 5230
AC1L1D8U
AC1Q1LA0
ACETYLSALICYLIC ACID
AI3-02956
AIN
AKOS000118884
ASA
Acenterine
Acesal
Acetal
Acetard
Aceticyl
Acetilsalicilico
Acetilum acidulatum
Acetisal
Acetol
Acetonyl
Acetophen
Acetosal
Acetosalic acid
Acetosalin
Acetoxybenzoic acid
Acetylin
Acetylsal
Acetylsalicylate
Acetylsalicylic acid
Acetylsalicylsaeure
Acetylsalicylsaure
Acetylsalycilic acid
Acetyonyl
Acetysal
Acetysalicylic acid
Acide 2-(acetyloxy)benzoique
Acide acetylsalicylique
Acide acétylsalicylique
Acido O-acetil-benzoico
Acido acetilsalicilico
Acidum acetylsalicylicum
Acimetten
Acisal
Acylpyrin
Adiro
Aloxiprimum
Asacard
Asagran
Asatard
Ascoden-30
Aspalon
Aspec
Aspergum
Aspir-Mox
Aspirdrops
Aspirin
Aspirin (JP15/USP)
Aspirin [BAN:JAN]
Aspirina 03
Aspirine
Asprin
Aspro
Aspro Clear
Asteric
Azetylsalizylsaeure
Azetylsalizylsäure
BIDD:GT0118
BRN 0779271
Bay-e-4465
Bayer
Bayer Aspirin 8 Hour
Bayer Buffered
Bayer Extra Strength Aspirin For Migraine Pain
Bayer Plus
Benaspir
Bi-prin
Bialpirina
Bialpirinia
Bufferin
C01405
CCRIS 3243
CHEBI:15365
CHEMBL25
CID2244
Caprin
Cardioaspirin
Cardioaspirina
Cemirit
Claradin
Clariprin
Colfarit
Contrheuma retard
Coricidin
Crystar
D00109
D001241
DB00945
Decaten
Delgesic
Dispril
DivK1c_000555
Dolean pH 8
Duramax
ECM
EINECS 200-064-1
EU-0100038
Easprin
Easprin (TN)
Ecolen
Ecotrin
Empirin
Empirin with Codeine
Endosprin
Endydol
 
Entericin
Enterophen
Enterosarein
Enterosarine
Entrophen
Extren
Globentyl
Globoid
HMS1920E13
HMS2090G03
HMS2091K13
HMS501L17
HSDB 652
Helicon
I14-7505
IDI1_000555
Idragin
Istopirin
KBio1_000555
KBio2_001725
KBio2_002271
KBio2_004293
KBio2_004839
KBio2_006861
KBio2_007407
KBio3_002149
KBio3_002751
KBioGR_000398
KBioGR_002271
KBioSS_001725
KBioSS_002272
Kapsazal
Kyselina 2-acetoxybenzoova
Kyselina acetylsalicylova
LS-143
Levius
Lopac-A-5376
Lopac0_000038
MLS001055329
MLS001066332
MLS001336045
MLS001336046
Magnecyl
Measurin
Medisyl
Micristin
MolPort-000-871-622
NCGC00015067-01
NCGC00015067-04
NCGC00015067-09
NCGC00090977-01
NCGC00090977-02
NCGC00090977-03
NCGC00090977-04
NCGC00090977-05
NCGC00090977-06
NCGC00090977-07
NCI60_002222
NINDS_000555
NSC 27223
NSC27223
NSC406186
Neuronika
Novid
Nu-seals
Nu-seals aspirin
O-(Acetyloxy)benzoate
O-(Acetyloxy)benzoic acid
O-Acetoxybenzoate
O-Acetoxybenzoic acid
O-Acetylsalicylic acid
O-Carboxyphenyl acetate
O-accetylsalicylic acid
O-acetylsalicylic acid
PL-2200
Persistin
Pharmacin
Pirseal
Polopirin
Polopiryna
Premaspin
R16CO5Y76E [UNII]
Rheumin tabletten
Rheumintabletten
Rhodine
Rhonal
Ronal
S-211
SMR000059138
SP 189
SPBio_001838
SPECTRUM1500130
ST075414
Salacetin
Salcetogen
Saletin
Salicylic acid acetate
Salicylic acid, acetate
Salospir
Solfrin
Solprin
Solprin acid
Solpyron
Solupsan
Spectrum2_001899
Spectrum3_001295
Spectrum4_000099
Spectrum5_000740
Spectrum_001245
Spira-Dine
St. Joseph
St. Joseph Aspirin for Adults
Supac
Tasprin
Temperal
Toldex
Triaminicin
Triple-sal
UNII R16CO5Y76E
UNII-R16CO5Y76E
UNII=R16CO5Y76E
UNM-0000306102
Vanquish
WLN: QVR BOV1
XAXA
Xaxa
Yasta
ZORprin
aspirin
cMAP_000006
component of Midol
component of Synirin
nchem.859-comp6
o-Acetoxybenzoic acid
o-Carboxyphenyl acetate
o-acetoxybenzoic acid
o-carboxyphenyl acetate
ácido acetilsalicílico
3
Dexmedetomidineapproved, vet_approvedPhase 4, Phase 3, Phase 154076631-46-4, 113775-47-668602, 5311068, 56032
Synonyms:
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
(+)-medetomidine
(S)-medetomidine
113775-47-6
4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
AC1NSJXT
C07450
CHEBI:4466
CHEMBL778
CID5311068
D00514
DEXMEDETOMIDINE
 
Dexdor (T)
Dexmedetomidin
Dexmedetomidina
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexmedetomidinum
Dexmédétomidine
MPV 1440
MPV-1440
Medetomidina [Spanish]
Medetomidine
Medetomidinum [Latin]
NCGC00025347-01
PRECEDEX
Precedex (TN)
Tocris-2023
ZINC04632106
4
Ketamineapproved, vet_approvedPhase 4, Phase 25286740-88-13821
Synonyms:
(+-)-Ketamine
(+/-)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone
(+/-)-2-(o-Chlorophenyl)-2-(methylamino)cyclohexanone
(+/-)-Ketamine
(-)-Ketamine
(S)-(-)-Ketamine
(S)-Ketamine
(±)-ketamine
100477-72-3
2-(2-Chloro-phenyl)-2-methylamino-cyclohexanone
2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone
2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one
2-(Methylamino)-2-(2-chlorophenyl)cyclohexanone
2-(methylamino)-2-(2-chlorophenyl)cyclohexanone
2-(o-Chlorophenyl)-2-(methylamino)-cyclohexanone
2-(o-Chlorophenyl)-2-(methylamino)cyclohexanone
2-(o-chlorophenyl)-2-(methylamino)-cyclohexanone
33643-45-7
6740-88-1
79499-51-7
AC1L1GSH
AC1Q40UR
AKOS001053247
BRN 2216965
C07525
C13H16ClNO
CHEBI:138833
CHEBI:6121
CHEMBL742
CI 581 base
CI-581
CID3821
CLSTA 20
Calypsol
Cetamina
Cetamina [INN-Spanish]
Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)- (9CI)
Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, (+-)- (9CI)
Cyclohexanone, 2-(o-chlorophenyl)-2-(methylamino)-, (+/-)- (8CI)
D08098
DB01221
DEA No. 7285
 
DL-ketamine
DivK1c_000217
EINECS 229-804-1
Esketamine
Green
IDI1_000217
KBio1_000217
KETAMINE
KETAMINE HCL
Ketaject
Ketalar
Ketalar base
Ketamina
Ketamine (INN)
Ketamine Base
Ketamine HCL
Ketamine [INN:BAN]
Ketaminum
Ketaminum [INN-Latin]
Ketanest
Ketoject
Ketolar
L-Ketamine
LS-57301
MLS001331674
MolPort-001-838-070
NCGC00159480-02
NCGC00159480-03
NINDS_000217
NMDA
NSC 70151
NSC70151
SMR000238141
Special K
Special K [street name]
Special k
T385
Tekam
Tekam (TN)
UNII-690G0D6V8H
dl-Ketamine
ketamine
l-Ketamine
5
Epinephrineapproved, vet_approvedPhase 493351-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr.
Epipen Jr. Auto-Injector
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
Esphygmogenina
Exadrin
 
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
6
Oxycodoneapproved, illicit, investigationalPhase 436476-42-65284603
Synonyms:
(-)-14-Hydroxydihydrocodeinone
(-)-Oxycodone
(5alpha)-14-hydroxy-17-methyl-3-(methyloxy)-4,5-epoxymorphinan-6-one
124-90-3 (hydrochloride)
14-Hydroxydihydrocodeinone
14-hydroxy-3-methoxy-17-methyl-4,5alpha-epoxymorphinan-6-one
25333-72-6 (Terephthalate)
4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
4,5.alpha.-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
4,5alpha-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
4,5α-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
76-42-6
AC-16043
AC1Q4DTG
BRN 0043446
C08018
CHEBI:7852
CHEMBL656
CID5284603
Combunox
D05312
DB00497
DEA No. 9143
Dihydro-14-hydroxycodeinone
Dihydrohydroxycodeinone
Dihydrohydroxycondeinone
Dihydrone
Dihydroxycodeinone
Dinarkon
Diphydrone
EINECS 200-960-2
Endine (Australia)
Endocet
Endodan
Endone
Eubine
Eubine [France]
Eucodal
Eucodalum
Eukodal
Eutagen
HSDB 3142
Hydroxycodeinon
LS-92148
MolPort-004-285-989
Morphinan-6-one, 4,5alpha-epoxy-14-hydroxy-3-methoxy-17-methyl- (8CI)
NSC 19043
NSC19043
 
Ossicodone
Ossicodone [DCIT]
Oxanest
Oxicodona
Oxicodona [INN-Spanish]
Oxicon
Oxicone
Oxiconum
Oxikon
OxyFAST
OxyIR
OxyNorm
Oxycodeinon
Oxycodeinone
Oxycodon
Oxycodone
Oxycodone (USAN/INN)
Oxycodone Concentrate
Oxycodone Hcl
Oxycodone Hydrochloride
Oxycodone [USAN:INN:BAN]
Oxycodone hydrochloride
Oxycodonum
Oxycodonum [INN-Latin]
Oxycon
Oxycone
Oxycontin
Oxyfast
Oxynorm
PTI-821
Pancodine
Pancodone retard (United Kingdom)
Percobarb
Percodan
Percolone
Remoxy
Roxicet
Roxicodone
Supendol
Supendol [Canada]
Supeudol
Tecodin
Tekodin
Tekodin (free base)
Thecodine
Thekodin
Theocodin
UNII-CD35PMG570
WLN: T B6566 B6/CO 4ABBC R BX FV HO PN GHT&&TTJ CQ JO1 P1
oxycodone
7
Bupivacaineapproved, investigationalPhase 411312180-92-9, 38396-39-32474
Synonyms:
( inverted exclamation markA)-bupivacaine
(+-)-Bupivacaine
(1)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
(RS)-bupivacaine
(±)-bupivacaine
1-Butyl-2',6'-pipecoloxylidide
1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
15233-43-9
2180-92-9
38396-39-3
AB00053674
AC-2096
AC1L1DRE
AC1Q5LX4
AH 250
AKOS001637202
AR-1A0242
Anekain
BPBio1_000298
BRD-A01636364-003-05-2
BSPBio_000270
BSPBio_002607
Bio-0886
Bloqueina
Bucaine
Bucaine (TN)
Bupivacaina
Bupivacaina [INN-Spanish]
Bupivacaine (INN)
Bupivacaine Carbonate
Bupivacaine HCL
Bupivacaine HCL KIT
Bupivacaine Monohydrochloride, Monohydrate
Bupivacaine [INN:BAN]
Bupivacainum
Bupivacainum [INN-Latin]
Bupivan
C07529
C18H28N2O
CBupivacaine
CHEBI:3215
CHEMBL1098
CID2474
Carbostesin
D07552
DB00297
DL-Bupivacaine
DUR-843
 
DepoBupivacaine
DivK1c_000758
EINECS 218-553-3
EINECS 253-911-2
HMS2090F12
IDI1_000758
KBio1_000758
KBio2_002004
KBio2_004572
KBio2_007140
KBio3_001827
KBioGR_001516
KBioSS_002004
KST-1A4609
L000695
LAC-43
LS-109841
LS-2222
MLS001361336
Marcaina
Marcaine
Marcaine HCL
Marcaine Spinal
MolPort-004-955-820
NCGC00178579-01
NCGC00178579-02
NINDS_000758
NSC119660
Prestwick0_000305
Prestwick1_000305
Prestwick2_000305
Prestwick3_000305
SMR000058218
SPBio_001558
SPBio_002489
Sensorcaine
Sensorcaine-MPF
Sensorcaine-MPF Spinal
Spectrum2_001589
Spectrum3_000974
Spectrum4_001098
Spectrum5_001483
Spectrum_001524
Transdur-Bupivacaine
UNII-Y8335394RO
Win 11318
Win 11318 HCl
bupivacaine
cBupivacaine
dl-1-Butyl-2',6'-pipecoloxylidide
racemic bupivacaine
8
Propofolapproved, investigational, vet_approvedPhase 410282078-54-84943
Synonyms:
2, 6-Diisopropylphenol
2,6 Diisopropylphenol
2,6-Bis(1-methylethyl)phenol
2,6-Bis(Isopropyl)-phenol
2,6-DIISOPROPYLPHENOL
2,6-Diisopropyl phenol
2,6-Diisopropylphenol
2,6-bis(1-methylethyl)-phenol
2,6-di(propan-2-yl)phenol
2078-54-8
28449-97-0
4-06-00-03435 (Beilstein Handbook Reference)
50356-15-5
AB00513968
AC-2038
AC1L1J9Y
AC1Q1OUI
AI3-26295
AM-149
Abbott Brand of Propofol
Alpha Brand of Propofol
Ampofol
Aquafol
Astra Brand of Propofol
AstraZeneca Brand of Propofol
BIDD:GT0436
BPBio1_000950
BPBio1_000969
BRD-K82255054-001-03-5
BRN 1866484
BSPBio_000862
Biomol-NT_000248
Braun Brand of Propofol
C07523
C12H18O
CAS-2078-54-8
CCRIS 9000
CHEBI:44915
CHEMBL526
CID4943
CPD-11437
CPD000059151
Curamed Brand of Propofol
D00549
D015742
D0617
D126608
D126608_ALDRICH
DB00818
DDS-04F
Diisopropylphenol
Dipravan
Diprivan
Diprivan (TN)
Diprivan Injectable emulsion
Disoprivan
Disoprofol
EINECS 218-206-6
EU-0100437
Fresenius Brand of Propofol
Fresenius Kabi Brand of Propofol
Fresofol
HMS1570L04
HMS2089O21
HMS2094E17
 
HSDB 7123
ICI 35,868
ICI 35868
ICI-35,868
ICI-35868
ICI35,868
ICI35868
InChI=1/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H
Ivofol
Jsp004266
Juste Brand of Propofol
LS-996
Lopac-D126608
Lopac0_000437
MLS001066348
MLS001335999
MLS002454360
MolPort-001-794-517
NCGC00015389-01
NCGC00015389-02
NCGC00015389-04
NCGC00015389-09
NCGC00091538-01
NCGC00091538-02
NCGC00091538-03
NCGC00091538-04
NCGC00091538-05
NCGC00091538-06
NSC 5105
NSC5105
PFL
Parnell Brand of Propofol
Pisa Brand of Propofol
Prestwick0_000931
Prestwick1_000931
Prestwick2_000931
Prestwick3_000931
Propofol
Propofol (JAN/USAN/INN)
Propofol Abbott
Propofol Fresenius
Propofol IDD-D
Propofol MCT
Propofol Rovi
Propofol [USAN:INN:BAN]
Propofol(2,6-Diisopropylphenol)
Propofol-Lipuro
Propofolum
Propofolum [Latin]
Rapinovet
Recofol
Rovi Brand of Propofol
S01-0189
SAM002264610
SMR000059151
SPBio_003031
SPECTRUM1505022
ST50405911
Schering Brand of Propofol
UNII-YI7VU623SF
W505102_ALDRICH
ZD-0859
ZINC00968303
Zeneca Brand of Propofol
ghl.PD_Mitscher_leg0.558
nchembio.552-comp7
propofol
9
TiclopidineapprovedPhase 445755142-85-35472
Synonyms:
5-((2-Chlorophenyl)methyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridine
5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine
55142-85-3
AC-15204
AC1L1KFB
BIDD:PXR0169
BPBio1_000191
BRD-K00603606-003-03-4
BRN 1216802
BSPBio_000173
C07140
C14H14ClNS
CAS-53885-35-1
CHEBI:9588
CHEMBL833
CID5472
D08594
DB00208
EINECS 259-498-5
HMS2089I18
L001108
LS-152434
MLS001201825
MolPort-002-507-849
 
NCGC00016872-01
NCGC00016872-02
NCGC00024361-04
PCR 5332
Prestwick0_000047
Prestwick1_000047
Prestwick2_000047
Prestwick3_000047
SMR000641861
SPBio_002094
STK589340
STOCK5S-54105
Ticlid
Ticlopidin-Puren
Ticlopidin-Puren (TN)
Ticlopidina
Ticlopidina [INN-Spanish]
Ticlopidine (INN)
Ticlopidine HCL
Ticlopidine Hydrochloride
Ticlopidine [INN:BAN]
Ticlopidinum
Ticlopidinum [INN-Latin]
UNII-OM90ZUW7M1
UNM-0000345023
ZINC19594599
ticlopidine
10
Clopidogrelapproved, nutraceuticalPhase 4, Phase 3, Phase 2756120202-66-6, 113665-84-260606
Synonyms:
( )-(S)-Clopidogrel
(+)-(S)-Clopidogrel
(+)-Clopidogrel
(S)-Clopidogrel
(S)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate
113665-84-2
AC-19024
AC1L1TKZ
AC1Q41I9
BIDD:GT0284
BRD-K27721098-065-02-9
BSPBio_003211
C16H16ClNO2S
CGE
CHEBI:37941
CHEMBL1771
CID60606
CLOPIDOGREL SULFATE
CPD000550475
Clopidogrel
Clopidogrel (INN)
Clopidogrel (TN)
Clopidogrel [BAN:INN]
Clopidogrel [Ban:Inn]
Clopidogrel [INN:BAN]
Clopidogrel bisulfate
Clopidogrel bisulphate
Clopidogrel sulfate
Clopidogrelum
D07729
DB00758
DivK1c_000787
HMS2090O21
HMS502H09
HSDB 7430
IDI1_000787
 
Isocover
KBio1_000787
KBio2_000545
KBio2_003113
KBio2_005681
KBio3_002431
KBioGR_000689
KBioSS_000545
LS-172232
MLS001165708
MLS001195633
MLS001304711
Methyl (+)-(S)-alpha-(o-chlorophenyl)-6,7-dihydrothieno(3,2-c)pyridine-5(4H)-acetate
MolPort-002-885-817
MolPort-003-845-991
NCGC00163329-02
NINDS_000787
Plavix
Plavix (TN)
SAM002589956
SMR000550475
SPBio_000463
SR 25990
STK580572
STOCK5S-27782
Spectrum2_000512
Spectrum3_001606
Spectrum4_000175
Spectrum_000105
TL8000400
UNII-A74586SNO7
Zyllt
clopidogrel
clopidogrel, (+)(S)-isomer
methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoate
methyl (2S)-2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate
nchem.651-comp8
11AnalgesicsPhase 4, Phase 2, Phase 3, Phase 111287
12Analgesics, Non-NarcoticPhase 4, Phase 2, Phase 3, Phase 16260
13AnticoagulantsPhase 4, Phase 3, Phase 22516
14AntipyreticsPhase 4, Phase 2, Phase 31534
15Fibrinolytic AgentsPhase 4, Phase 3, Phase 22317
16Peripheral Nervous System AgentsPhase 4, Phase 2, Phase 3, Phase 122776
17Neurotransmitter AgentsPhase 4, Phase 3, Phase 2, Phase 117734
18Cyclooxygenase InhibitorsPhase 4, Phase 3, Phase 22778
19Antirheumatic AgentsPhase 4, Phase 3, Phase 210627
20Cytochrome P-450 Enzyme InhibitorsPhase 43822
21Pharmaceutical SolutionsPhase 4, Phase 3, Phase 27793
22Anti-Inflammatory AgentsPhase 4, Phase 3, Phase 210355
23Adrenergic AgentsPhase 4, Phase 3, Phase 15140
24Anti-Inflammatory Agents, Non-SteroidalPhase 4, Phase 3, Phase 24295
25Hypnotics and SedativesPhase 4, Phase 3, Phase 12485
26Excitatory Amino AcidsPhase 4, Phase 21297
27AnestheticsPhase 4, Phase 29001
28Adrenergic alpha-AgonistsPhase 4, Phase 3, Phase 11625
29Adrenergic alpha-2 Receptor AgonistsPhase 4, Phase 3, Phase 1911
30Adrenergic AgonistsPhase 4, Phase 3, Phase 12877
31Anesthetics, DissociativePhase 4, Phase 2507
32Anesthetics, GeneralPhase 4, Phase 22787
33Excitatory Amino Acid AntagonistsPhase 4, Phase 21282
34Platelet Aggregation InhibitorsPhase 4, Phase 3, Phase 1, Phase 22419
35Central Nervous System DepressantsPhase 4, Phase 3, Phase 2, Phase 112806
36Anesthetics, IntravenousPhase 4, Phase 22406
37RacepinephrinePhase 4933
38Epinephryl boratePhase 4933
39CarticainePhase 424
40Anesthetics, LocalPhase 43272
41Purinergic P2 Receptor AntagonistsPhase 4, Phase 2769
42Chelating AgentsPhase 41365
43Purinergic P2Y Receptor AntagonistsPhase 4, Phase 2767
44Bronchodilator AgentsPhase 42856
45Tocolytic AgentsPhase 4708
46Autonomic AgentsPhase 49774
47Respiratory System AgentsPhase 44818
48Anti-Asthmatic AgentsPhase 43369
49Adrenergic beta-2 Receptor AgonistsPhase 4925
50Adrenergic beta-AgonistsPhase 41640

Interventional clinical trials:

(show top 50)    (show all 130)
idNameStatusNCT IDPhase
1Bronchoscopic Closure of Bronchopleural Fistulas With Occlutech Figulla ASD N Occluder DeviceUnknown statusNCT01153074Phase 4
2PC-Trial: Patent Foramen Ovale and Cryptogenic EmbolismUnknown statusNCT00166257Phase 4
3Long-term Safety Study of the GORE® HELEX® Septal OccluderCompletedNCT00581308Phase 4
4Patent Foramen Ovale in Cryptogenic Stroke StudyCompletedNCT00697151Phase 4
5Comparative Effects of Dexmedetomidine and Ketofol for Sedation in Patients Undergoing Trans-esophageal EchocardiographyRecruitingNCT02867930Phase 4
6Comparison of the Local Anaesthetics Articaine and Bupivacaine in Treatment of Acute Sternum Pain After Heart SurgeryRecruitingNCT01536717Phase 4
7Device Closure Versus Medical Therapy for Cryptogenic Stroke Patients With High-Risk Patent Foramen Ovale (DEFENSE-PFO)RecruitingNCT01550588Phase 4
8Clopidogrel For the Prevention of New Onset Migraine Headache Following Transcatheter Closure of Atrial Septal DefectsActive, not recruitingNCT00799045Phase 4
9The Cardiopulmonary Effect of Inhaled Beta-2-agonists on Adult Patients Born With Ventricular Septum Defects.Not yet recruitingNCT02914652Phase 4
10Endoscopic Closure of Tracheoesophageal Fistulas With Occluder DeviceTerminatedNCT01153061Phase 4
11Mesh Ablator Versus Cryoballoon Pulmonary Vein Ablation of Symptomatic Paroxysmal Atrial FibrillationTerminatedNCT01061931Phase 4
12MIST II PFO-Migraine Trial With BioSTAR® Bioabsorbable Septal Repair ImplantUnknown statusNCT00283738Phase 2, Phase 3
13Evaluation of the STARFlex® Septal Closure System in Patients With a Stroke or TIA Due to the Possible Passage of a Clot of Unknown Origin Through a Patent Foramen Ovale (PFO)Unknown statusNCT00201461Phase 2, Phase 3
14Bosentan for Mild Pulmonary Vascular Disease in Asd Patients.CompletedNCT01218607Phase 3
15The Pharmacology and Hemodynamics of Dexmedetomidine in Children With Congenital Heart DiseaseCompletedNCT00480740Phase 3
16Concomitant Utilization of Radio Frequency Energy for Atrial Fibrillation (CURE-AF) StudyCompletedNCT00431834Phase 3
17Medtronic Concomitant Utilization of Radio Frequency for Atrial Fibrillation CURE-AF/PersistentCompletedNCT00506493Phase 3
18Infant Heart Surgery: Central Nervous System Sequelae of Circulatory ArrestCompletedNCT00000470Phase 3
19Minimally Invasive Transthoracic Device Closure in Perimembranous Ventricular Septal DefectRecruitingNCT02644330Phase 2, Phase 3
20GORE® HELEX® Septal Occluder / GORE® Septal Occluder for Patent Foramen Ovale (PFO) Closure in Stroke Patients - The Gore REDUCE Clinical StudyActive, not recruitingNCT00738894Phase 3
21Patent Foramen Ovale Closure or Anticoagulants Versus Antiplatelet Therapy to Prevent Stroke RecurrenceActive, not recruitingNCT00562289Phase 3
22Safety and Effectiveness of the Nit-Occlud® Lê VSD Spiral Coil SystemSuspendedNCT00390702Phase 2, Phase 3
23ESCAPE Migraine TrialTerminatedNCT00267371Phase 3
24Right to Left Cardiac Shunt DetectionTerminatedNCT01773252Phase 3
25Angiotensin Converting Enzyme Inhibition in Children With Mitral RegurgitationTerminatedNCT00113698Phase 3
26Cardiox Shunt Detection Technology StudyTerminatedNCT01333761Phase 3
27Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery : Revised ProtocolCompletedNCT01120964Phase 1, Phase 2
28Use of Ketamine Prior to Cardiopulmonary Bypass in ChildrenCompletedNCT00556361Phase 2
29Oral Sildenafil and Intravenous Milrinone on Postoperative Pulmonary HypertensionCompletedNCT02595541Phase 1, Phase 2
30Hypertonic Saline Dextran in Pediatric Cardiac SurgeryCompletedNCT00199771Phase 2
31Premium Migraine TrialCompletedNCT00355056Phase 2
32Feasibility Trial of the DC Devices Interatrial Septal Device (IASD) SystemCompletedNCT01570517Phase 1, Phase 2
33Intra-Cardiac Echocardiography Guided Cardioversion(ICE-CHIP) StudyCompletedNCT00281073Phase 1, Phase 2
34Left Ventricular Septum Pacing in Patients by Transvenous Approach Through the Inter-ventricular SeptumCompletedNCT01609738Phase 1, Phase 2
35Precutaneous High Risk Patent Foramen Ovale to Treat Migraine HeadachesNot yet recruitingNCT02777359Phase 2
36Catheter Thrombectomy in Patients With Massive Pulmonary EmbolismTerminatedNCT00314002Phase 1, Phase 2
37PRIMA PFO Migraine TrialTerminatedNCT00505570Phase 2
38Patients With Patent Foramen Ovale and Endocardial Device Leads on Apixaban for Prevention of Paradoxical EmboliWithdrawnNCT02378623Phase 2
39Aberrations in Carnitine Homeostasis in Congenital Heart Disease With Increased Pulmonary Blood FlowUnknown statusNCT01825369Phase 1
40Closure of Muscular Ventricular Septal Defects With The AMPLATZER® Muscular VSD OccluderUnknown statusNCT00583791Phase 1
41Closure of Perimembranous Ventricular Septal Defects With The AMPLATZER® Membranous VSD OCCLUDERCompletedNCT00578708Phase 1
42A Phase I Study of Dexmedetomidine Bolus and Infusion in Corrective Infant Cardiac Surgery: Safety and PharmacokineticsRecruitingNCT01915277Phase 1
43Radiation-Free Heart Catheterization Using MRIRecruitingNCT02739087Phase 1
44Transcaval Access for Transcatheter Aortic Valve Replacement in People With No Good Options for Aortic AccessEnrolling by invitationNCT02280824Phase 1
45Study of Energy Expenditure in Infants With Ventricular Septal DefectsUnknown statusNCT00006272
46Aortic Regurgitation After Surgical Repair of Outlet-Type Ventricular Septal DefectUnknown statusNCT00173186
47Study of Blood Clotting After Transcatheter Atrial Septal Defect ClosureUnknown statusNCT01086046
48Closure of Atrial Septal Defects With the AMPLATZER Septal Occluder - Post Approval StudyUnknown statusNCT00650936
49InterSEPT: In‐Tunnel SeptRx European PFO TrialUnknown statusNCT01385670
50Acetaminophen for Oxidative Stress After Cardiopulmonary BypassUnknown statusNCT01228305

Search NIH Clinical Center for Heart Septal Defect


Cochrane evidence based reviews: heart septal defects

Genetic Tests for Heart Septal Defect

About this section

Anatomical Context for Heart Septal Defect

About this section

MalaCards organs/tissues related to Heart Septal Defect:

35
Heart, Brain

Animal Models for Heart Septal Defect or affiliated genes

About this section

MGI Mouse Phenotypes related to Heart Septal Defect:

40 (show all 12)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053719.6CITED2, GATA4, GATA6, MEF2C, TBX1, TBX5
2MP:00053829.2ACVRL1, CITED2, GDF1, MEF2C, NKX2-5, NODAL
3MP:00053978.4ACVRL1, CITED2, CLNK, GATA4, GATA6, GDF1
4MP:00053807.7ACVRL1, BMP10, CITED2, GATA4, GATA6, GDF1
5MP:00053697.5ACVRL1, BMP10, GATA4, GATA6, MEF2C, NKX2-5
6MP:00028737.3ACVRL1, BMP10, CITED2, GATA4, GATA6, GDF1
7MP:00053847.3BMP10, CA5B, CITED2, GATA4, GATA6, GDF1
8MP:00053767.2ACVRL1, BMP10, CA5B, CITED2, GATA4, GATA6
9MP:00053857.0ACVRL1, BMP10, CITED2, GATA4, GATA6, GDF1
10MP:00053786.9ACVRL1, BMP10, CA5B, CITED2, GATA4, GATA6
11MP:00053886.9ACVRL1, CITED2, GATA4, GATA6, GDF1, MEF2C
12MP:00107686.0ACVRL1, BMP10, CA5B, CITED2, GATA4, GATA6

Publications for Heart Septal Defect

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Articles related to Heart Septal Defect:

idTitleAuthorsYear
1
Pulmonary arterial hypertension in adults born with a heart septal defect: the Euro Heart Survey on adult congenital heart disease. (17164490)
2007

Variations for Heart Septal Defect

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Copy number variations for Heart Septal Defect from CNVD:

6 (show all 28)
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1161575221940537520797502DeletionAIFM3cardiac septal defect
2161576221940537520797502DeletionCCDC116cardiac septal defect
3161577221940537520797502DeletionCRKLcardiac septal defect
4161578221940537520797502DeletionFLJ42953cardiac septal defect
5161579221940537520797502DeletionGGT-2cardiac septal defect
6161580221940537520797502DeletionHIC2cardiac septal defect
7161581221940537520797502DeletionLOC150223cardiac septal defect
8161582221940537520797502DeletionLOC220686cardiac septal defect
9161583221940537520797502DeletionLOC400891cardiac septal defect
10161584221940537520797502DeletionLZTR1cardiac septal defect
11161585221940537520797502DeletionMAPK1cardiac septal defect
12161586221940537520797502DeletionMGC16703cardiac septal defect
13161587221940537520797502DeletionP2RXL1cardiac septal defect
14161588221940537520797502DeletionPIKA4CAcardiac septal defect
15161589221940537520797502DeletionPPIL2cardiac septal defect
16161590221940537520797502DeletionPPM1Fcardiac septal defect
17161591221940537520797502DeletionRBP3.2cardiac septal defect
18161592221940537520797502DeletionRBP3.3cardiac septal defect
19161593221940537520797502DeletionSDF2L1cardiac septal defect
20161594221940537520797502DeletionSERPIND1cardiac septal defect
21161595221940537520797502DeletionSLC7A4cardiac septal defect
22161596221940537520797502DeletionSNAP29cardiac septal defect
23161597221940537520797502DeletionTHAP7cardiac septal defect
24161598221940537520797502DeletionTOP3Bcardiac septal defect
25161599221940537520797502DeletionUBE2L3cardiac septal defect
26161600221940537520797502DeletionYPEL1cardiac septal defect
27161601221940537520797502Deletionmir-130bcardiac septal defect
28161602221940537520797502Deletionmir-301bcardiac septal defect

Expression for genes affiliated with Heart Septal Defect

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Search GEO for disease gene expression data for Heart Septal Defect.

Pathways for genes affiliated with Heart Septal Defect

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GO Terms for genes affiliated with Heart Septal Defect

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Biological processes related to Heart Septal Defect according to GeneCards Suite gene sharing:

(show all 50)
idNameGO IDScoreTop Affiliating Genes
1atrial cardiac muscle cell developmentGO:005501410.8NKX2-5, NKX2-6
2bundle of His developmentGO:000316610.8NKX2-5, TBX5
3cardiac muscle tissue morphogenesisGO:005500810.7NKX2-5, TBX20
4right ventricular cardiac muscle tissue morphogenesisGO:000322110.7NKX2-5, ZFPM2
5cardiac right ventricle morphogenesisGO:000321510.7GATA4, TBX20
6pericardium developmentGO:006003910.7NKX2-6, TBX5
7embryonic heart tube left/right pattern formationGO:006097110.6CITED2, NKX2-5
8cardiac ventricle formationGO:000321110.6MEF2C, NKX2-5
9cardiac septum developmentGO:000327910.6CRELD1, TBX20
10intestinal epithelial cell differentiationGO:006057510.6GATA4, GATA6
11cardiac muscle cell proliferationGO:006003810.6BMP10, NKX2-5
12nodal signaling pathwayGO:003809210.5CFC1, NODAL
13embryonic process involved in female pregnancyGO:006013610.5CITED2, NODAL
14nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetryGO:190016410.5CITED2, NODAL
15positive regulation of cell-cell adhesionGO:002240910.5CITED2, NODAL
16adult heart developmentGO:000751210.5BMP10, NKX2-5
17cardiac ventricle morphogenesisGO:000320810.5GATA4, NKX2-5
18pharyngeal system developmentGO:006003710.4NKX2-5, NKX2-6, TBX1
19ventricular septum morphogenesisGO:006041210.4CITED2, NKX2-5, ZFPM2
20positive regulation of male gonad developmentGO:200002010.4CITED2, ZFPM2
21embryonic viscerocranium morphogenesisGO:004870310.3MEF2C, TBX1
22ventricular cardiac muscle cell developmentGO:005501510.3BMP10, NKX2-5, NKX2-6
23positive regulation of cardioblast differentiationGO:005189110.3GATA4, GATA6, NKX2-5, TBX5
24transdifferentiationGO:006029010.3GATA4, MEF2C, TBX5
25cardiac muscle tissue developmentGO:004873810.3GATA6, NKX2-5, ZFPM2
26cell developmentGO:004846810.3GATA4, GATA6, GDF1
27ventricular septum developmentGO:000328110.2CITED2, GATA4, TBX5
28endocardial cushion developmentGO:000319710.2CITED2, CRELD1, GATA4, TBX5
29atrial septum morphogenesisGO:006041310.2GATA4, NKX2-5, TBX20, TBX5
30SMAD protein signal transductionGO:006039510.2BMP10, GDF1, NODAL
31embryonic heart tube developmentGO:003505010.1NKX2-5, NKX2-6, NODAL, TBX20
32positive regulation of BMP signaling pathwayGO:003051310.1ACVRL1, GATA4, GATA6
33blood vessel developmentGO:000156810.0CITED2, MEF2C, TBX1
34cell fate commitmentGO:00451659.9GATA4, GATA6, MEF2C, NODAL
35cardiac muscle cell differentiationGO:00550079.8GATA4, GATA6, MEF2C, NKX2-5, TBX5
36outflow tract septum morphogenesisGO:00031489.8GATA6, NKX2-5, TBX1, TBX20, ZFPM2
37vasculogenesisGO:00015709.8CITED2, NKX2-5, TNNI3, ZFPM2
38positive regulation of angiogenesisGO:00457669.7ACVRL1, GATA4, GATA6, NODAL
39positive regulation of pathway-restricted SMAD protein phosphorylationGO:00108629.7ACVRL1, BMP10, GDF1, NODAL
40determination of left/right symmetryGO:00073689.6CFC1, CITED2, NODAL, TBX1
41outflow tract morphogenesisGO:00031519.5CITED2, MEF2C, NKX2-5, TBX1, TBX20
42in utero embryonic developmentGO:00017019.4ACVRL1, CITED2, GATA6, NODAL, ZFPM2
43BMP signaling pathwayGO:00305099.4ACVRL1, BMP10, GDF1, NKX2-5, NODAL
44heart loopingGO:00019479.3CITED2, GATA4, MEF2C, NKX2-5, NODAL, TBX20
45positive regulation of cardiac muscle cell proliferationGO:00600459.3BMP10, GATA6, MEF2C, TBX20, TBX5, ZFPM2
46negative regulation of cell migrationGO:00303369.2ACVRL1, BMP10, CITED2, TBX5
47negative regulation of transcription from RNA polymerase II promoterGO:00001228.3CITED2, GATA6, MEF2C, NKX2-5, NODAL, TBX20
48positive regulation of transcription, DNA-templatedGO:00458937.7ACVRL1, BMP10, CITED2, GATA4, GATA6, MEF2C
49heart developmentGO:00075077.7BMP10, CITED2, MEF2C, NKX2-5, NKX2-6, NODAL
50positive regulation of transcription from RNA polymerase II promoterGO:00459447.4ACVRL1, CITED2, GATA4, GATA6, MEF2C, NKX2-5

Molecular functions related to Heart Septal Defect according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1RNA polymerase II transcription coactivator activityGO:000110510.3CITED2, TBX20, ZFPM2
2transforming growth factor beta receptor bindingGO:000516010.2BMP10, GDF1, NODAL
3transcription factor activity, RNA polymerase II distal enhancer sequence-specific bindingGO:000370510.1GATA6, MEF2C, NKX2-5
4transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific bindingGO:000122810.0GATA4, GATA6, NKX2-5, TBX5
5RNA polymerase II transcription factor bindingGO:00010859.9GATA4, GATA6, TBX20, ZFPM2
6transcription regulatory region DNA bindingGO:00442129.6GATA4, GATA6, MEF2C, NKX2-5
7RNA polymerase II regulatory region sequence-specific DNA bindingGO:00009779.5GATA4, GATA6, MEF2C, TBX20, TBX5
8transcription factor bindingGO:00081349.3GATA4, GATA6, NKX2-5, TBX5, ZFPM2
9chromatin bindingGO:00036829.2CITED2, GATA4, GATA6, MEF2C, NKX2-5
10sequence-specific DNA bindingGO:00435658.4GATA4, GATA6, MEF2C, NKX2-5, NKX2-6, TBX1
11transcription factor activity, sequence-specific DNA bindingGO:00037008.3CITED2, GATA4, GATA6, MEF2C, NKX2-5, NKX2-6

Sources for Heart Septal Defect

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet