MCID: HRT011
MIFTS: 34

Heart Septal Defect malady

Category: Cardiovascular diseases

Aliases & Classifications for Heart Septal Defect

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Aliases & Descriptions for Heart Septal Defect:

Name: Heart Septal Defect 10 12
Heart Septal Defects 36 65
Septal Defect 10 47
 
Congenital Septal Defect of Heart 10
Cardiac Septal Defects 10
Septal Defect Nos 10

Classifications:



External Ids:

Disease Ontology10 DOID:1681
ICD1027 Q21, Q21.9
MeSH36 D006343
NCIt42 C84482
UMLS65 C0018816

Summaries for Heart Septal Defect

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Wikipedia:68 Heart septal defect refers to a congenital heart defect of one of the septa of the heart. more...

MalaCards based summary: Heart Septal Defect, also known as heart septal defects, is related to atrioventricular septal defect and atrial heart septal defect. An important gene associated with Heart Septal Defect is NKX2-5 (NK2 Homeobox 5), and among its related pathways are HOP Signaling and Cardiomyocyte Differentiation through BMP Receptors. Affiliated tissues include heart and brain, and related mouse phenotypes are craniofacial and respiratory system.

Related Diseases for Heart Septal Defect

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Diseases related to Heart Septal Defect via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 49)
idRelated DiseaseScoreTop Affiliating Genes
1atrioventricular septal defect30.7GATA4, GATA6, NKX2-5, NKX2-6
2atrial heart septal defect12.6
3ventricular septal defect11.9
4lymphedema-atrial septal defects-facial changes syndrome11.5
5hyperphosphatasia with mental retardation syndrome 210.5
6aorto-right ventricular tunnel10.5CRELD1, GATA4
7inferior vena cava interruption10.5CRELD1, GATA4
8dysmorphism-short stature-deafness-disorder of sex development syndrome10.4GATA4, ZFPM2
9dextrocardia with unusual facies and microphthalmia10.3CITED2, NODAL
10univentricular heart with single atrio-ventricular valve10.3CRELD1, GATA4, GATA6
11partial deletion of y10.3CRELD1, GATA4, GATA6
12subvalvular aortic stenosis10.3CRELD1, NODAL
13diaphragm disease10.3NKX2-6, ZFPM2
14gerbode defect10.3CITED2, GATA4, NKX2-5, NKX2-6
15leopard syndrome10.2CRELD1, GATA4, NKX2-5, NKX2-6
16childhood central nervous system mature teratoma10.2CRELD1, GATA4, NKX2-6, TBX5
17ichthyosis lamellar 110.2NKX2-5, NKX2-6, TNNI3
18joubert syndrome 1310.2NKX2-5, TBX1, TBX5
19uterine corpus serous adenocarcinoma10.2CRELD1, GATA4, GATA6, NKX2-6
20hemangioma10.2CRELD1, NKX2-6, TNNI3
21chromophobe adenoma10.2GATA4, GATA6, ZFPM2
22holt-oram syndrome10.1TBX1, TBX5
23sclerosing cholangitis10.1BLVRA, NKX2-6
24dentinogenesis imperfecta, shields type ii10.1CRELD1, NKX2-6
25stork bite10.0CRELD1, NKX2-6, NODAL, TNNI3
26systemic lupus erythematosus10.0
27otitis media10.0
28cataract10.0
29anisometropia10.0
30graves' disease10.0
31bardet-biedl syndrome10.0
32kidney disease10.0
33lupus erythematosus10.0
34linear scleroderma10.0
35endotheliitis10.0
36mitral valve insufficiency10.0ACVRL1, NKX2-6
37neovascular glaucoma9.9CFC1, GATA4, NKX2-5, TBX5, TNNI3
38vitelliform macular dystrophy9.9CRELD1, GATA4, GATA6, NKX2-5, NKX2-6, TBX5
39hemolytic disease of the newborn with kell alloimmunization9.9GATA6, NKX2-5, NKX2-6, TBX1, ZFPM2
40testicular trophoblastic tumor9.9ACVRL1, BLVRA, CRELD1
41spinal canal and spinal cord meningioma9.8CFC1, CRELD1, GATA4, NKX2-5, NKX2-6, TNNI3
42rheumatic heart disease9.8ACVRL1, CRELD1, GATA6, NKX2-5, NKX2-6
43campylobacteriosis9.7CITED2, CLNK, GATA4, GATA6, NKX2-5, NKX2-6
44transverse limb deficiency hemangioma9.6CFC1, CRELD1, GATA6, NKX2-5, NKX2-6, TBX1
45supratentorial cancer9.6CITED2, GATA4, GATA6, NKX2-5, NKX2-6, NODAL
46hepatitis c9.4ACVRL1, CLNK, CRELD1, GATA4, NKX2-5, NKX2-6
47slowed nerve conduction velocity, ad9.3CITED2, CRELD1, GATA4, GATA6, NKX2-5, NKX2-6
48surfactant metabolism dysfunction, pulmonary, 28.7CFC1, CITED2, CRELD1, GATA4, GATA6, NKX2-5
49congenital heart disease6.4ACVRL1, BLVRA, BMP10, CA5B, CFC1, CITED2

Graphical network of the top 20 diseases related to Heart Septal Defect:



Diseases related to heart septal defect

Symptoms for Heart Septal Defect

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Drugs & Therapeutics for Heart Septal Defect

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Drugs for Heart Septal Defect (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 107)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
WarfarinapprovedPhase 4, Phase 2, Phase 342281-81-26691, 54678486
Synonyms:
(-)-Warfarin
(S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone
(S)-Warfarin
(phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarin
(phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarine
1-(4'-Hydroxy-3'-coumarinyl)-1-phenyl-3-butanone
200 Coumarin
200 coumarin
3-(1'-Phenyl-2'-acetylethyl)-4-hydroxycoumarin
3-(Acetonylbenzyl)-4-hydroxycoumarin
3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin
3-(alpha-Phenyl-beta-acetylaethyl)-4-hydroxycumarin
3-(alpha-Phenyl-beta-acetylethyl)-4-hydroxycoumarin
4-Hydroxy-3- (3-oxo-1-fenyl-butyl) cumarine
4-Hydroxy-3- (3-oxo-1-phenyl-butyl)-cumarin
4-Hydroxy-3-(3-oxo-1-fenyl-butyl) cumarine
4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-cumarin
4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one
4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one
4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin
4-Idrossi-3- (3-oxo-)-fenil-butil)-cumarine
4-Idrossi-3-(3-oxo-)-fenil-butil)-cumarine
4-Idrossi-3-(3-oxo-1-fenil-butil)-cumarine
45706_FLUKA
45706_RIEDEL
4oh-coumarin deriv.
5543-56-6
5543-57-7
81-81-2
A2250_FLUKA
A2250_SIGMA
AC-15978
AC1L1N37
AC1Q6AN3
AR-1E2310
Arab Rat Death
Arab rat death
Arab rat deth
Athrombin
Athrombin-K
Athrombin-k
Athrombine-K
Athrombine-k
BRD-A24514565-001-02-2
BRD-A24514565-236-01-6
BRN 1293536
BSPBio_002026
Bio-0586
Brumolin
C01541
C19H16O4
CBDivE_002127
CBDivE_013236
CBKinase1_000192
CBKinase1_012592
CHEBI:10033
CHEMBL1464
CID6691
CO-Rax
Caswell No. 903
Choice
Choice (TN)
Co-Rax
Co-rax
Compound 42
Coumadin
Coumadin Tabs
Coumafen
Coumafene
Coumafene [French]
Coumaphen
Coumaphene
Coumarins
Coumefene
Cov-R-Tox
Cov-R-tox
D-Con
D08682
DB00682
DL-3-(alpha-acetonylbenzyl)-4-hydroxycoumarin
Dethmor
Dethnel
Dicusat E
Dicusat e
DivK1c_000444
EINECS 201-377-6
EINECS 226-907-3
EPA Pesticide Chemical Code 086002
Eastern states duocide
Fasco fascrat powder
Frass-Ratron
Frass-ratron
HMS1921K07
HMS2092C20
HMS501G06
HSDB 1786
I14-0958
IDI1_000444
Jantoven
KBio1_000444
KBio2_000674
KBio2_003242
KBio2_005810
KBio3_001526
KBioGR_000901
KBioSS_000674
Killgerm sewarin p
Kumader
Kumadu
Kumatox
Kypfarin
LS-55083
Latka 42
Latka 42 [Czech]
Liqua-tox
MLS001304042
Maag Rattentod Cum
Maag rattentod cum
Mar-Frin
Mar-frin
Marevan
Martin'S mar-frin
Martin's mar-frin
 
Maveran
MolPort-001-787-822
Mouse pak
NCGC00094810-01
NCGC00094810-02
NCGC00159398-03
NCGC00178855-01
NINDS_000444
NSC 59813
NSC59813
PS104_SUPELCO
Panwarfin
Place-Pax
Place-pax
Prothromadin
RAX
RCR grey squirrel killer concentrate
RCRA waste no. P001
Rat & mice bait
Rat and mice bait
Rat-B-gon
Rat-Gard
Rat-Kill
Rat-Mix
Rat-O-cide #2
Rat-O-cide no. 2
Rat-Ola
Rat-Trol
Rat-a-way
Rat-alpha-way
Rat-b-gon
Rat-beta-gon
Rat-gard
Rat-kill
Rat-mix
Rat-o-cide #2
Rat-ola
Rat-trol
Ratorex
Ratox
Ratoxin
Ratron
Ratron G
Ratron g
Rats-no-more
Ratten-Koederrohr
Ratten-koederrohr
Rattenstreupulver Neu Schacht
Rattenstreupulver neu schacht
Rattenstreupulver new schacht
Rattentraenke
Rattunal
Rcra waste number P001
Ro-Deth
Ro-deth
Rodafarin
Rodafarin C
Rodafarin c
Rodex
Rodex blox
Rosex
Rough & ready mouse mix
Rough and ready mouse mix
SMP1_000316
SMR000718754
SPBio_000870
SPECTRUM1500613
STK364490
Sakarat
Sewarin
Sofarin
Solfarin
Sorexa Plus
Sorexa plus
Spectrum2_000935
Spectrum3_000583
Spectrum4_000381
Spectrum5_001751
Spectrum_000194
Spray-trol brand roden-trol
Temus W
Temus w
Tintorane
Tox-Hid
Tox-hid
Twin light rat away
UNII-5Q7ZVV76EI
Vampirinip II
Vampirinip III
Vampirinip iii
W.A.R.F. 42
WARF compound 42
WLN: T66 BOVJ DYR&1V1 EQ
Waran
Warf 10
Warf 42
Warfarat
Warfarin (INN)
Warfarin (and salts of)
Warfarin Plus
Warfarin Q
Warfarin Sodium
Warfarin [BSI:ISO]
Warfarin [INN:BAN]
Warfarin plus
Warfarin plus [discontinued]
Warfarin sodium
Warfarin titrated to an INR of 2.5-3.0
Warfarin(R)
Warfarina
Warfarina [INN-Spanish]
Warfarine
Warfarine [INN-French]
Warfarine [ISO-French]
Warfarinum
Warfarinum [INN-Latin]
Warficide
Warfilone
Zoocoumarin
Zoocoumarin [Netherlands and USSR]
Zoocoumarin [Russian]
delta-Con
nchembio.307-comp19
rac-Warfarin
warfarin
2
AspirinapprovedPhase 4, Phase 2, Phase 3102950-78-22244
Synonyms:
11126-35-5
11126-37-7
1oxr
2-(ACETYLOXY)benzoic acid
2-(Acetyloxy)benzoate
2-(Acetyloxy)benzoic acid
2-Acetoxybenzenecarboxylic acid
2-Acetoxybenzoate
2-Acetoxybenzoic acid
2-Carboxyphenyl acetate
2349-94-2
26914-13-6
50-78-2
7 Select Adult Chewable Aspirin
7 Select Aspirin
8-hour Bayer
98201-60-6
A 5376
A.S.A
A.S.A.
A.S.A. Empirin
A.S.A. empirin
A2093_SIGMA
A3160_SIGMA
A5376_SIGMA
A6810_SIGMA
AB1003266
AC 5230
AC1L1D8U
AC1Q1LA0
ACETYLSALICYLIC ACID
AI3-02956
AIN
AKOS000118884
ASA
Acenterine
Acesal
Acetal
Acetard
Aceticyl
Acetilsalicilico
Acetilum acidulatum
Acetisal
Acetol
Acetonyl
Acetophen
Acetosal
Acetosalic acid
Acetosalin
Acetoxybenzoic acid
Acetylin
Acetylsal
Acetylsalicylate
Acetylsalicylic acid
Acetylsalicylsaeure
Acetylsalicylsaure
Acetylsalycilic acid
Acetyonyl
Acetysal
Acetysalicylic acid
Acide 2-(acetyloxy)benzoique
Acide acetylsalicylique
Acide acétylsalicylique
Acido O-acetil-benzoico
Acido acetilsalicilico
Acidum acetylsalicylicum
Acimetten
Acisal
Acylpyrin
Adiro
Adult Chewable Low Dose Aspirin
Adult Low Dose Aspirin
Adult Low Dose Aspirin Enteric Safety Coated
Adult Low Dose Enteric Coated Aspirin
Adult Low Strength Aspirin
Aloxiprimum
Asacard
Asagran
Asaphen
Asatard
Ascoden-30
Ascriptin Maximum Strength Buffered Aspirin
Ascriptin Regular Strength Buffered Aspirin
Aspalon
Aspec
Aspergum
Aspi-cor
Aspir Low
Aspir-Mox
Aspirdrops
Aspirin
Aspirin (JP15/USP)
Aspirin 81 Mg
Aspirin 81 Mg Low Dose
Aspirin Adult Low Dose
Aspirin Adult Low Strength
Aspirin Adult Low Strength Aspirin
Aspirin Adult low strength
Aspirin Chewable Low Dose
Aspirin Delayed Release
Aspirin EC
Aspirin EXTRA STRENGTH
Aspirin Ec
Aspirin Enteric
Aspirin Enteric Coated
Aspirin Enteric Coated Low Dose
Aspirin Enteric Safety Coated
Aspirin Enteric Safety-Coated
Aspirin Low Dose
Aspirin Low Dose Chewable
Aspirin Low Dose Enteric Coated
Aspirin Low Dose Safety Coated
Aspirin Low Strength
Aspirin Nsaid
Aspirin Regular Strength
Aspirin Regular Strength regular strength
Aspirin Regular strength
Aspirin Safety Coated
Aspirin Safety Coated Adult Low Dose
Aspirin Safety coated
Aspirin Thin coated
Aspirin [BAN:JAN]
Aspirin adult low dose
Aspirin adult low strength
Aspirin enteric safety coated
Aspirin low dose
Aspirin low dose chewable
Aspirin low dose enteric coated
Aspirin regular strength
Aspirina 03
Aspirine
Aspiring
Asprin
Aspro
Aspro Clear
Asteric
Azetylsalizylsaeure
Azetylsalizylsäure
BIDD:GT0118
BRN 0779271
Bay-e-4465
Bayer
Bayer Advanced Aspirin Extra Strength
Bayer Advanced Aspirin Regular Strength
Bayer Aspirin 8 Hour
Bayer Aspirin Regimen Chewable Low Dose Aspirin Orange
Bayer Aspirin Regimen Regular Strength
Bayer Buffered
Bayer Chewable - Aspirin Regimen Low Dose Aspirin Cherry Flavored
Bayer Extra Strength Aspirin For Migraine Pain
Bayer Fast Release
Bayer Genuine Aspirin
Bayer Low Dose
Bayer Plus
Bayer Plus Extra Strength
Bayer Womens
Benaspir
Bi-prin
Bialpirina
Bialpirinia
Buffered Aspirin
Bufferin
Bufferin LOW DOSE BUFFERED ASPIRIN
C01405
CCRIS 3243
CHEBI:15365
CHEMBL25
CID2244
Caprin
Cardioaspirin
Cardioaspirina
Care One Aspirin
Cemirit
Chewable Adult Low Dose Aspirin
Chewable Aspirin
Chewable Low Dose Aspirin
Claradin
Clariprin
Colfarit
Contrheuma retard
Coricidin
Critical Care Aspirin To Go
Crystar
D00109
D001241
DB00945
Decaten
Delgesic
Dg Health Aspirin
Direct Safety Aspirin
Dispril
DivK1c_000555
Dolean pH 8
Duramax
ECM
EINECS 200-064-1
EU-0100038
Easprin
Easprin (TN)
Ec-81aspirin Enteric Coated
Ecolen
Ecotrin
Ecotrin Regular Strength
Empirin
Empirin with Codeine
Endosprin
Endydol
Enteric Aspirin
Enteric Coated Aspirin
Enteric Coated Aspirin Regular Strength
Enteric Coated Aspirin Regular strength
Enteric Coated Aspirin regular strength
Enteric Coated Asprin 81 Mg
Enteric Coated Low Dose Aspirin
 
Enteric Safety Coated Aspirin
Entericin
Enterophen
Enterosarein
Enterosarine
Entrophen
Equaline Aspirin
Equaline Aspirin adult low dose
Equate Aspirin
Equate Aspirin chewable
Extren
Fasprin
Flanax Aspirin Pain Reliever
Formucare Aspirin
Genuine Aspirin
Globentyl
Globoid
Good Neighbor Pharmacy Aspirin
Good Neighbor Pharmacy Aspirin Enteric Safety Coated
Good Neighbor Pharmacy Aspirin orange flavor chewable
Good Sense Aspirin
Good Sense Aspirin Enteric Safety Coated
HMS1920E13
HMS2090G03
HMS2091K13
HMS501L17
HSDB 652
Handy Solutions Genuine Aspirin Bayer
Health Mart Aspirin
Health Mart Regular Strength Enteric Coated Aspirin
Health Sense Adult Chewable Low Strength Aspirin
Health Sense Aspirin 81
Health Sense Ecpirin
Healthy Accents Aspirin
Helicon
Henry Schein Aspirin
I14-7505
IDI1_000555
Idragin
Istopirin
KBio1_000555
KBio2_001725
KBio2_002271
KBio2_004293
KBio2_004839
KBio2_006861
KBio2_007407
KBio3_002149
KBio3_002751
KBioGR_000398
KBioGR_002271
KBioSS_001725
KBioSS_002272
Kapsazal
Kroger Value Aspirin
Kyselina 2-acetoxybenzoova
Kyselina acetylsalicylova
LS-143
Leader Aspirin
Leader Cardinal Health Aspirin
Leader Low Dose Aspirin
Levius
Lopac-A-5376
Lopac0_000038
Low Dose Adult Aspirin
Low Dose Aspirin
Low Dose Aspirin 81 Mg Safety Coated
Low Dose Aspirin Enteric Safety Coated
Low Dose Asprin
Low Dose Chewable Aspirin
Low Dose Miniprin Enteric Safety Coated
Low Dose Pain Relief Aspirin
Low Strength Chewable Aspirin
Low-dose Aspirin
MLS001055329
MLS001066332
MLS001336045
MLS001336046
Magnecyl
Measurin
Medi First Plus Aspirin
Medi-first Aspirin
Medique Aspirin
Medisyl
Micristin
Micro-coated Aspirin
Miniprin
MolPort-000-871-622
NCGC00015067-01
NCGC00015067-04
NCGC00015067-09
NCGC00090977-01
NCGC00090977-02
NCGC00090977-03
NCGC00090977-04
NCGC00090977-05
NCGC00090977-06
NCGC00090977-07
NCI60_002222
NINDS_000555
NSC 27223
NSC27223
NSC406186
Neuronika
North Aspirin
Novasen
Novid
Nu-seals
Nu-seals aspirin
O-(Acetyloxy)benzoate
O-(Acetyloxy)benzoic acid
O-Acetoxybenzoate
O-Acetoxybenzoic acid
O-Acetylsalicylic acid
O-Carboxyphenyl acetate
O-accetylsalicylic acid
O-acetylsalicylic acid
PL-2200
Pain Relief Aspirin
Pain Relief Aspirin Low Dose
Persistin
Pharbest Aspirin 325mg
Pharbest Regular Strength Aspirin
Pharmacin
Pirseal
Plus Pharma NSAID 325 mg
Plus Pharma Nsaid Aspirin
Polopirin
Polopiryna
Premaspin
R16CO5Y76E [UNII]
Rapid Comfort Aspirin
Regular Strength Aspirin
Regular Strength Aspirin Ec
Regular Strength Buffered Aspirin
Regular Strength Enteric Aspirin
Regular Strength Enteric Coated Aspirin
Regular Strength Pain Relief
Regular Strength Tri-buffered Aspirin
Rexall Aspirin
Rheumin tabletten
Rheumintabletten
Rhodine
Rhonal
Ronal
Rugby Aspirin
Rx Act Aspirin
S-211
SMR000059138
SP 189
SPBio_001838
SPECTRUM1500130
ST075414
Safety Coated Aspirin
Safety Coated Enteric Aspirin
Salacetin
Salcetogen
Saletin
Salicylic acid acetate
Salicylic acid, acetate
Salospir
Smart Health Aspirin regular strength
Smart Sense Aspirin
Solfrin
Solprin
Solprin acid
Solpyron
Solupsan
Solves - Aspirin Cherry
Spectrum2_001899
Spectrum3_001295
Spectrum4_000099
Spectrum5_000740
Spectrum_001245
Spira-Dine
St. Joseph
St. Joseph Aspirin for Adults
St. Joseph Chewable Aspirin
St. Joseph Safety Coated Aspirin
Sunmark Aspirin
Sunmark Aspirin Regular Strength
Sunmark Aspirin adult low strength
Sunmark Aspirin low dose
Supac
Tasprin
Temperal
Toldex
Topcare Aspirin
Tri-buffered Aspirin
Triaminicin
Triple-sal
UNII R16CO5Y76E
UNII-R16CO5Y76E
UNII=R16CO5Y76E
UNM-0000306102
Uncoated Aspirin
Value Pharma Aspirin Pain Reliever
Value Pharmapain Reliever Extra Strength
Vanquish
WLN: QVR BOV1
XAXA
Xaxa
Yasta
ZORprin
Zee Aspirin
aspirin
cMAP_000006
component of Midol
component of Synirin
nchem.859-comp6
o-Acetoxybenzoic acid
o-Carboxyphenyl acetate
o-acetoxybenzoic acid
o-carboxyphenyl acetate
ácido acetilsalicílico
3
Bupivacaineapproved, investigationalPhase 49642180-92-92474
Synonyms:
( inverted exclamation markA)-bupivacaine
(+-)-Bupivacaine
(1)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
(RS)-bupivacaine
1-Butyl-2',6'-pipecoloxylidide
1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
15233-43-9
2180-92-9
38396-39-3
AB00053674
AC-2096
AC1L1DRE
AC1Q5LX4
AH 250
AKOS001637202
AR-1A0242
Anekain
BPBio1_000298
BRD-A01636364-003-05-2
BSPBio_000270
BSPBio_002607
Bio-0886
Bloqueina
Bucaine
Bucaine (TN)
Bupivacaina
Bupivacaina [INN-Spanish]
Bupivacaine
Bupivacaine (INN)
Bupivacaine Carbonate
Bupivacaine HCL
Bupivacaine HCL KIT
Bupivacaine Hydrochloride
Bupivacaine Monohydrochloride, Monohydrate
Bupivacaine [INN:BAN]
Bupivacainum
Bupivacainum [INN-Latin]
Bupivan
C07529
C18H28N2O
CBupivacaine
CHEBI:3215
CHEMBL1098
CID2474
Carbostesin
D07552
DB00297
DL-Bupivacaine
DUR-843
DepoBupivacaine
 
DivK1c_000758
EINECS 218-553-3
EINECS 253-911-2
Exparel
HMS2090F12
IDI1_000758
KBio1_000758
KBio2_002004
KBio2_004572
KBio2_007140
KBio3_001827
KBioGR_001516
KBioSS_002004
KST-1A4609
L000695
LAC-43
LS-109841
LS-2222
MLS001361336
Marcaina
Marcaine
Marcaine HCL
Marcaine Spinal
MolPort-004-955-820
NCGC00178579-01
NCGC00178579-02
NINDS_000758
NSC119660
Prestwick0_000305
Prestwick1_000305
Prestwick2_000305
Prestwick3_000305
Racemic bupivacaine
SMR000058218
SPBio_001558
SPBio_002489
Sensorcaine
Sensorcaine-MPF
Sensorcaine-MPF Spinal
Spectrum2_001589
Spectrum3_000974
Spectrum4_001098
Spectrum5_001483
Spectrum_001524
Transdur-Bupivacaine
UNII-Y8335394RO
Vivacaine
Win 11318
Win 11318 HCl
bupivacaine
cBupivacaine
dl-1-Butyl-2',6'-pipecoloxylidide
4
Oxycodoneapproved, illicit, investigationalPhase 433376-42-65284603
Synonyms:
(-)-14-Hydroxydihydrocodeinone
(-)-Oxycodone
(5alpha)-14-hydroxy-17-methyl-3-(methyloxy)-4,5-epoxymorphinan-6-one
124-90-3 (hydrochloride)
14-Hydroxydihydrocodeinone
14-hydroxy-3-methoxy-17-methyl-4,5alpha-epoxymorphinan-6-one
25333-72-6 (Terephthalate)
4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
4,5.alpha.-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
4,5alpha-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
76-42-6
AC-16043
AC1Q4DTG
BRN 0043446
C08018
CHEBI:7852
CHEMBL656
CID5284603
Combunox
D05312
DB00497
DEA No. 9143
Dihydro-14-hydroxycodeinone
Dihydrohydroxycodeinone
Dihydrohydroxycondeinone
Dihydrone
Dihydroxycodeinone
Dinarkon
Diphydrone
EINECS 200-960-2
Endine (Australia)
Endocet
Endodan
Endone
Eubine
Eubine [France]
Eucodal
Eucodalum
Eukodal
Eutagen
HSDB 3142
Hydroxycodeinon
LS-92148
MolPort-004-285-989
Morphinan-6-one, 4,5alpha-epoxy-14-hydroxy-3-methoxy-17-methyl- (8CI)
NSC 19043
NSC19043
Ossicodone
 
Ossicodone [DCIT]
Oxanest
Oxecta
Oxicodona
Oxicodona [INN-Spanish]
Oxicon
Oxicone
Oxiconum
Oxikon
OxyFAST
OxyIR
OxyNorm
Oxycodeinon
Oxycodeinone
Oxycodon
Oxycodone
Oxycodone (USAN/INN)
Oxycodone Concentrate
Oxycodone Hcl
Oxycodone Hydrochloride
Oxycodone [USAN:INN:BAN]
Oxycodone hydrochloride
Oxycodonum
Oxycodonum [INN-Latin]
Oxycon
Oxycone
Oxycontin
Oxyfast
Oxynorm
PTI-821
Pancodine
Pancodone retard (United Kingdom)
Percobarb
Percodan
Percolone
Remoxy
Roxicet
Roxicodone
Supendol
Supendol [Canada]
Supeudol
Tecodin
Tekodin
Tekodin (free base)
Thecodine
Thekodin
Theocodin
UNII-CD35PMG570
WLN: T B6566 B6/CO 4ABBC R BX FV HO PN GHT&&TTJ CQ JO1 P1
oxycodone
5
EpinephrineapprovedPhase 483451-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenaclick
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
Auvi-q
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine bitartrate
Epinephrine chloride
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr
Epipen Jr.
Epipen Jr. Auto-Injector
Epipen jr
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
 
Esphygmogenina
Exadrin
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
Primatene Mist Refill
Prime Asthma Relief
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
6
TiclopidineapprovedPhase 419355142-85-35472
Synonyms:
5-((2-Chlorophenyl)methyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridine
5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine
55142-85-3
AC-15204
AC1L1KFB
BIDD:PXR0169
BPBio1_000191
BRD-K00603606-003-03-4
BRN 1216802
BSPBio_000173
C07140
C14H14ClNS
CAS-53885-35-1
CHEBI:9588
CHEMBL833
CID5472
D08594
DB00208
EINECS 259-498-5
HMS2089I18
L001108
LS-152434
MLS001201825
MolPort-002-507-849
 
NCGC00016872-01
NCGC00016872-02
NCGC00024361-04
PCR 5332
Prestwick0_000047
Prestwick1_000047
Prestwick2_000047
Prestwick3_000047
SMR000641861
SPBio_002094
STK589340
STOCK5S-54105
Ticlid
Ticlopidin-Puren
Ticlopidin-Puren (TN)
Ticlopidina
Ticlopidina [INN-Spanish]
Ticlopidine (INN)
Ticlopidine HCL
Ticlopidine Hydrochloride
Ticlopidine [INN:BAN]
Ticlopidinum
Ticlopidinum [INN-Latin]
UNII-OM90ZUW7M1
UNM-0000345023
ZINC19594599
ticlopidine
7
Clopidogrelapproved, nutraceuticalPhase 4, Phase 3, Phase 2717120202-66-6, 113665-84-260606
Synonyms:
( )-(S)-Clopidogrel
(+)-(S)-Clopidogrel
(+)-Clopidogrel
(S)-Clopidogrel
(S)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate
113665-84-2
AC-19024
AC1L1TKZ
AC1Q41I9
BIDD:GT0284
BRD-K27721098-065-02-9
BSPBio_003211
C16H16ClNO2S
CGE
CHEBI:37941
CHEMBL1771
CID60606
CLOPIDOGREL SULFATE
CPD000550475
Clopidogrel
Clopidogrel (INN)
Clopidogrel (TN)
Clopidogrel Bisulfate
Clopidogrel [BAN:INN]
Clopidogrel [Ban:Inn]
Clopidogrel [INN:BAN]
Clopidogrel bisulfate
Clopidogrel bisulphate
Clopidogrel sulfate
Clopidogrelum
D07729
DB00758
DivK1c_000787
HMS2090O21
HMS502H09
HSDB 7430
 
IDI1_000787
Isocover
KBio1_000787
KBio2_000545
KBio2_003113
KBio2_005681
KBio3_002431
KBioGR_000689
KBioSS_000545
LS-172232
MLS001165708
MLS001195633
MLS001304711
Methyl (+)-(S)-alpha-(o-chlorophenyl)-6,7-dihydrothieno(3,2-c)pyridine-5(4H)-acetate
MolPort-002-885-817
MolPort-003-845-991
NCGC00163329-02
NINDS_000787
Plavix
Plavix (TN)
SAM002589956
SMR000550475
SPBio_000463
SR 25990
STK580572
STOCK5S-27782
Spectrum2_000512
Spectrum3_001606
Spectrum4_000175
Spectrum_000105
TL8000400
UNII-A74586SNO7
Zyllt
clopidogrel
clopidogrel, (+)(S)-isomer
methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoate
methyl (2S)-2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate
nchem.651-comp8
8AnestheticsPhase 4, Phase 27385
9Central Nervous System DepressantsPhase 4, Phase 3, Phase 2, Phase 110016
10Pharmaceutical SolutionsPhase 4, Phase 3, Phase 27004
11AnalgesicsPhase 4, Phase 3, Phase 2, Phase 19358
12Cytochrome P-450 Enzyme InhibitorsPhase 43036
13Neurotransmitter AgentsPhase 4, Phase 3, Phase 2, Phase 114795
14Anti-Inflammatory Agents, Non-SteroidalPhase 4, Phase 33549
15AntipyreticsPhase 4, Phase 31140
16AnticoagulantsPhase 4, Phase 3, Phase 21760
17Analgesics, Non-NarcoticPhase 4, Phase 3, Phase 15184
18Platelet Aggregation InhibitorsPhase 4, Phase 3, Phase 1, Phase 21935
19Antirheumatic AgentsPhase 4, Phase 38496
20Anti-Inflammatory AgentsPhase 4, Phase 3, Phase 28478
21Peripheral Nervous System AgentsPhase 4, Phase 3, Phase 2, Phase 118510
22Fibrinolytic AgentsPhase 4, Phase 3, Phase 21567
23Cyclooxygenase InhibitorsPhase 4, Phase 32225
24CarticainePhase 422
25Anesthetics, LocalPhase 42347
26Epinephryl boratePhase 4834
27RacepinephrinePhase 4834
28Purinergic P2Y Receptor AntagonistsPhase 4654
29Purinergic P2 Receptor AntagonistsPhase 4656
30
Bosentanapproved, investigationalPhase 3100147536-97-8104865
Synonyms:
-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]benzenesulfonamide
147536-97-8
174227-18-0
4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide
4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl)benzenesulfornamide
4-t-butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide
4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide
4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide
AC-148
AC1L2XN2
Actelion
Bosentan
Bosentan (INN)
Bosentan [USAN:INN:BAN]
Bosentan hydrate
Bosentanum
C27H29N5O6S
CHEBI:51450
CHEMBL957
CID104865
D07538
 
DB00559
EN002863
HMS2090N14
I06-1873
KS-5062
L001086
LS-31532
MolPort-003-845-300
NCGC00167440-01
P-Tert-butyl-N-(6-(2-hydroxyethoxy)-5-(O-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide
PDSP1_001731
PDSP2_001714
Ro 47-0203
Ro 47-0203/039
Ro-47-0203
Ro-47-0203/029
Ro-47-0203/039
TL8001039
Tracleer
UNII-XUL93R30K2
bosentanum
p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide
p-tert-Butyl-N-[6-(2-hydroxyethoxy)
31
DexmedetomidineapprovedPhase 3, Phase 1470113775-47-668602, 5311068, 56032
Synonyms:
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
(+)-medetomidine
(S)-medetomidine
113775-47-6
4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
AC1NSJXT
C07450
CHEBI:4466
CHEMBL778
CID5311068
D00514
DEXMEDETOMIDINE
Dexdor (T)
 
Dexmedetomidin
Dexmedetomidina
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexmedetomidine Hydrochloride
Dexmedetomidinum
Dexmédétomidine
MPV 1440
MPV-1440
Medetomidina [Spanish]
Medetomidine
Medetomidinum [Latin]
NCGC00025347-01
PRECEDEX
Precedex
Precedex (TN)
Tocris-2023
ZINC04632106
32
ApixabanapprovedPhase 3, Phase 2111503612-47-310182969
Synonyms:
1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahyd
2p16
503612-47-3
AKOS005146204
Apixaban
Apixaban (JAN/USAN/INN)
Apixabanum
BMS 562247-01
BMS-562247
BMS-562247-01
 
BMS-562247-01, Apixaban
CHEBI:49620
CHEMBL231779
CID10182969
D03213
DB07828
Eliquis
GG2
S1593_Selleck
UNII-3Z9Y7UWC1J
ro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid amide
33
RivaroxabanapprovedPhase 3215366789-02-8
Synonyms:
BAY 59-7939
 
BAY59-7939
Xarelto
34
DipyridamoleapprovedPhase 37658-32-23108
Synonyms:
2,6-Bis(diethanolamine)-4,8-dipiperidinopyrimido[5,4-d]pyrimidine
2,6-Bis(diethanolamino)-4,8-dipiperidinopyrimido(5,4-d)pyrimidine
2,6-Bis(diethanolamino)-4,8-dipiperidinopyrimido[5,4-d]pyrimidine
4-26-00-03840 (Beilstein Handbook Reference)
58-32-2
AB00051974
AC-18100
AC1L1F6T
AC1Q7CXU
AC1Q7CXW
AC1Q7CXX
AKOS000509426
Agilease
Anginal
Antistenocardin
Apo-Dipyridamole
Apo-Dipyridamole Fc
Apo-Dipyridamole Sc
Apotex Brand of Dipyridamole
Apricor
Ashbourne Brand of Dipyridamole
BAS 00818792
BIM-0050449.0001
BPBio1_000270
BRD-K86301799-001-04-1
BRN 0068373
BSPBio_000244
BSPBio_001554
BSPBio_001924
Belmac Brand of Dipyridamole
Berlin Chemie Brand of Dipyridamole
Berlin-Chemie Brand of Dipyridamole
Bio-0173
Boehringer Ingelheim Brand of Dipyridamole
C24H40N8O4
CAS-58-32-2
CHEBI:4653
CHEMBL932
CID3108
CPD000058382
Cardioflux
Cardoxil
Cardoxin
Cerebrovase
Chilcolan
Cleridium
Cleridium 150
Coribon
Coridil
Coronarine
Corosan
Coroxin
Curantil
Curantyl
D 9766
D00302
D004176
D2274
D9766_SIGMA
DB00975
Dipiridamol
Dipiridamol [INN-Spanish]
Dipyramidole
Dipyridamine
Dipyridamol
Dipyridamole
Dipyridamole (JP15/USP/INN)
Dipyridamole [USAN:INN:BAN:JAN]
Dipyridamolum
Dipyridamolum [INN-Latin]
Dipyridan
Dipyudamine
DivK1c_000696
Dypyridamol
EINECS 200-374-7
EU-0100464
Gulliostin
HMS1568M06
HMS1791N16
HMS1920I10
HMS1989N16
HMS2089N15
HMS2091O18
 
HMS502C18
IDI1_000696
IPRAD Brand of Dipyridamole
Iv Persantine
Justpertin
KBio1_000696
KBio2_001484
KBio2_004052
KBio2_006620
KBio3_001144
KBioGR_001123
KBioSS_001484
Kurantil
LS-66732
Lopac-D-9766
Lopac0_000464
MLS000028420
MLS001076306
MLS001333724
Miosen
MolPort-001-792-504
NCGC00015385-01
NCGC00015385-02
NCGC00015385-03
NCGC00015385-07
NCGC00015385-15
NCGC00023914-02
NCGC00023914-04
NCGC00023914-05
NCGC00023914-06
NCGC00023914-07
NCGC00023914-08
NCGC00023914-09
NCGC00023914-10
NCGC00023914-11
NCI60_005689
NINDS_000696
NSC 515776
NSC-515776
NSC515776
Natyl
Novo-Dipiradol
Novopharm Brand of Dipyridamole
Peridamol
Permiltin
Permole, Persantine, Dipyridan, Dipyridamole
Persantin
Persantine
Persantine (TN)
Piroan
Prandiol
Prandiol 75
Prestwick0_000142
Prestwick1_000142
Prestwick2_000142
Prestwick3_000142
Prestwick_145
Protangix
RA 8
RA-8
S1867_Selleck
S1895_Selleck
SAM002264609
SMP2_000208
SMR000058382
SPBio_001003
SPBio_002183
SPECTRUM1500259
Spectrum2_000972
Spectrum3_000402
Spectrum4_000522
Spectrum5_000839
Spectrum_001004
Stenocardil
Stenocardiol
Stimolcardio
Tocris-0691
UNII-64ALC7F90C
UPCMLD-DP072
UPCMLD-DP072:001
Usaf Ge-12
WLN: T66 BN DN GN INJ CCN HCN E- AT6NTJ B2Q F2Q& J- AT6NTJ B2Q F2Q
ZINC00643046
dipyridamole
35
EnalaprilapprovedPhase 311275847-73-35362032, 40466924
Synonyms:
(2S)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid
(S)-1-(N-(1-(Ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline
(S)-1-{(S)-2-[1-((S)-ethoxycarbonyl)-3-phenyl-propylamino]-propionyl}-pyrrolidine-2-carboxylic acid
1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl ester
75847-73-3
AC1NTUS5
Analapril
BIDD:GT0751
BPBio1_000340
BSPBio_000308
BSPBio_003035
Bonuten
C06977
CAS-76095-16-4
CHEBI:116847
CHEBI:4784
CHEMBL578
CID5388962
D07892
DivK1c_000408
Enalapril
Enalapril (INN)
Enalapril (TN)
Enalapril Bp
Enalapril Maleate
Enalapril Richet
Enalaprila
Enalaprila [INN-Spanish]
Enalaprilat
Enalaprilum
 
Enalaprilum [INN-Latin]
Gadopril
HMS2090E08
IDI1_000408
KBio1_000408
KBio2_001787
KBio2_004355
KBio2_006923
KBio3_002535
KBioGR_000355
KBioSS_001787
Kinfil
LS-190651
MolPort-002-885-877
N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl-L-proline
N-{(1S)-1-[(ethyloxy)carbonyl]-3-phenylpropyl}-L-alanyl-L-proline
NCGC00016932-01
NCGC00021569-04
NCGC00021569-05
NCGC00021569-06
NINDS_000408
Prestwick3_000314
SPBio_001349
Spectrum2_001455
Spectrum3_001478
Spectrum4_000008
Spectrum5_001107
Spectrum_001307
Vaseretic
Vasotec
Vasotec IV
enalapril
36Hypnotics and SedativesPhase 3, Phase 12032
37Endothelin Receptor AntagonistsPhase 3189
38Adrenergic AgentsPhase 3, Phase 14204
39Antihypertensive AgentsPhase 33618
40Adrenergic alpha-AgonistsPhase 3, Phase 11300
41Adrenergic AgonistsPhase 3, Phase 12331
42Adrenergic alpha-2 Receptor AgonistsPhase 3, Phase 1790
43Protease InhibitorsPhase 3, Phase 24558
44Serine Proteinase InhibitorsPhase 3, Phase 2705
45HIV Protease InhibitorsPhase 3, Phase 24558
46Factor Xa InhibitorsPhase 3, Phase 2315
47AntithrombinsPhase 3, Phase 2574
48Antithrombin IIIPhase 3, Phase 2563
49Antivitamins KPhase 310
50Aspirin, Dipyridamole Drug CombinationPhase 326

Interventional clinical trials:

(show top 50)    (show all 123)
idNameStatusNCT IDPhase
1Long-term Safety Study of the GORE® HELEX® Septal OccluderCompletedNCT00581308Phase 4
2Patent Foramen Ovale in Cryptogenic Stroke StudyCompletedNCT00697151Phase 4
3EDWARDS INTUITY Valve System CADENCE-MIS StudyCompletedNCT02672553Phase 4
4Comparison of the Local Anaesthetics Articaine and Bupivacaine in Treatment of Acute Sternum Pain After Heart SurgeryRecruitingNCT01536717Phase 4
5Bronchoscopic Closure of Bronchopleural Fistulas With Occlutech Figulla ASD N Occluder DeviceRecruitingNCT01153074Phase 4
6Device Closure Versus Medical Therapy for Cryptogenic Stroke Patients With High-Risk Patent Foramen Ovale (DEFENSE-PFO)RecruitingNCT01550588Phase 4
7Clopidogrel For the Prevention of New Onset Migraine Headache Following Transcatheter Closure of Atrial Septal DefectsActive, not recruitingNCT00799045Phase 4
8PC-Trial: Patent Foramen Ovale and Cryptogenic EmbolismActive, not recruitingNCT00166257Phase 4
9EDWARDS INTUITY Valve System CADENCE StudyActive, not recruitingNCT02688153Phase 4
10Endoscopic Closure of Tracheoesophageal Fistulas With Occluder DeviceTerminatedNCT01153061Phase 4
11Mesh Ablator Versus Cryoballoon Pulmonary Vein Ablation of Symptomatic Paroxysmal Atrial FibrillationTerminatedNCT01061931Phase 4
12Bosentan for Mild Pulmonary Vascular Disease in Asd Patients.CompletedNCT01218607Phase 3
13The Pharmacology and Hemodynamics of Dexmedetomidine in Children With Congenital Heart DiseaseCompletedNCT00480740Phase 3
14Infant Heart Surgery: Central Nervous System Sequelae of Circulatory ArrestCompletedNCT00000470Phase 3
15Concomitant Utilization of Radio Frequency Energy for Atrial Fibrillation (CURE-AF) StudyCompletedNCT00431834Phase 3
16Medtronic Concomitant Utilization of Radio Frequency for Atrial Fibrillation CURE-AF/PersistentCompletedNCT00506493Phase 3
17Minimally Invasive Transthoracic Device Closure in Perimembranous Ventricular Septal DefectRecruitingNCT02644330Phase 2, Phase 3
18MIST II PFO-Migraine Trial With BioSTAR® Bioabsorbable Septal Repair ImplantActive, not recruitingNCT00283738Phase 2, Phase 3
19Evaluation of the STARFlex® Septal Closure System in Patients With a Stroke or TIA Due to the Possible Passage of a Clot of Unknown Origin Through a Patent Foramen Ovale (PFO)Active, not recruitingNCT00201461Phase 2, Phase 3
20GORE® HELEX® Septal Occluder / GORE® Septal Occluder for Patent Foramen Ovale (PFO) Closure in Stroke Patients - The Gore REDUCE Clinical StudyActive, not recruitingNCT00738894Phase 3
21Patent Foramen Ovale Closure or Anticoagulants Versus Antiplatelet Therapy to Prevent Stroke RecurrenceActive, not recruitingNCT00562289Phase 3
22Safety and Effectiveness of the Nit-Occlud® Lê VSD Spiral Coil SystemSuspendedNCT00390702Phase 2, Phase 3
23Angiotensin Converting Enzyme Inhibition in Children With Mitral RegurgitationTerminatedNCT00113698Phase 3
24Right to Left Cardiac Shunt DetectionTerminatedNCT01773252Phase 3
25ESCAPE Migraine TrialTerminatedNCT00267371Phase 3
26Cardiox Shunt Detection Technology StudyTerminatedNCT01333761Phase 3
27Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery : Revised ProtocolCompletedNCT01120964Phase 1, Phase 2
28Hypertonic Saline Dextran in Pediatric Cardiac SurgeryCompletedNCT00199771Phase 2
29Use of Ketamine Prior to Cardiopulmonary Bypass in ChildrenCompletedNCT00556361Phase 2
30Premium Migraine TrialCompletedNCT00355056Phase 2
31Oral Sildenafil and Intravenous Milrinone on Postoperative Pulmonary HypertensionCompletedNCT02595541Phase 1, Phase 2
32Feasibility Trial of the DC Devices Interatrial Septal Device (IASD) SystemCompletedNCT01570517Phase 1, Phase 2
33Intra-Cardiac Echocardiography Guided Cardioversion(ICE-CHIP) StudyCompletedNCT00281073Phase 1, Phase 2
34Left Ventricular Septum Pacing in Patients by Transvenous Approach Through the Inter-ventricular SeptumCompletedNCT01609738Phase 1, Phase 2
35Patients With Patent Foramen Ovale and Endocardial Device Leads on Apixaban for Prevention of Paradoxical EmboliRecruitingNCT02378623Phase 2
36Precutaneous High Risk Patent Foramen Ovale to Treat Migraine HeadachesNot yet recruitingNCT02777359Phase 2
37Catheter Thrombectomy in Patients With Massive Pulmonary EmbolismTerminatedNCT00314002Phase 1, Phase 2
38PRIMA PFO Migraine TrialTerminatedNCT00505570Phase 2
39Closure of Perimembranous Ventricular Septal Defects With The AMPLATZER® Membranous VSD OCCLUDERCompletedNCT00578708Phase 1
40Aberrations in Carnitine Homeostasis in Congenital Heart Disease With Increased Pulmonary Blood FlowRecruitingNCT01825369Phase 1
41Radiation-Free Heart Catheterization Using MRIRecruitingNCT02739087Phase 1
42A Phase I Study of Dexmedetomidine Bolus and Infusion in Corrective Infant Cardiac Surgery: Safety and PharmacokineticsRecruitingNCT01915277Phase 1
43Transcaval Access for Transcatheter Aortic Valve Replacement in People With No Good Options for Aortic AccessRecruitingNCT02280824Phase 1
44Closure of Muscular Ventricular Septal Defects With The AMPLATZER® Muscular VSD OccluderActive, not recruitingNCT00583791Phase 1
45Right Bundle Branch Block After Surgical Closure of Ventricular Septal DefectCompletedNCT01480908
46A Randomized Controlled Trial:Treatments on Infundibular Ventricular Septal DefectCompletedNCT02361008
47Transcatheter Closure Versus Surgery of Perimembranous Ventricular Septal DefectsCompletedNCT00890799
48Magnetic Resonance Imaging of Atrial Septal DefectsCompletedNCT00498446
49The Effect of Remote Ischemic Preconditioning on the Ischemic Reperfusion Injury in Infants With Ventricular Septal Defect and Pulmonary HypertensionCompletedNCT01313832
50Genes Causing Ebstein's AnomalyCompletedNCT00497705

Search NIH Clinical Center for Heart Septal Defect


Cochrane evidence based reviews: heart septal defects

Genetic Tests for Heart Septal Defect

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Anatomical Context for Heart Septal Defect

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MalaCards organs/tissues related to Heart Septal Defect:

33
Heart, Brain

Animal Models for Heart Septal Defect or affiliated genes

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MGI Mouse Phenotypes related to Heart Septal Defect:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053828.3ACVRL1, CITED2, MESP1, NKX2-5, NODAL, TBX1
2MP:00053887.2ACVRL1, CITED2, GATA4, GATA6, MESP1, NKX2-5
3MP:00053807.2ACVRL1, BMP10, CITED2, GATA4, GATA6, MESP1
4MP:00053847.1BMP10, CA5B, CITED2, GATA4, GATA6, MESP1
5MP:00028736.9ACVRL1, BMP10, CITED2, GATA4, GATA6, MESP1
6MP:00053696.7ACVRL1, BMP10, GATA4, GATA6, MESP1, NKX2-5
7MP:00053856.1ACVRL1, BMP10, CITED2, GATA4, GATA6, MESP1
8MP:00053766.1ACVRL1, BMP10, CA5B, CITED2, GATA4, GATA6
9MP:00053786.0ACVRL1, BMP10, CA5B, CITED2, GATA4, GATA6
10MP:00107685.5ACVRL1, BMP10, CA5B, CITED2, GATA4, GATA6

Publications for Heart Septal Defect

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Articles related to Heart Septal Defect:

idTitleAuthorsYear
1
Safety and Efficacy of Adding Fixed-Combination Brinzolamide/Timolol Maleate to Prostaglandin Therapy for Treatment of Ocular Hypertension or Glaucoma. (26495134)
2015

Variations for Heart Septal Defect

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Expression for genes affiliated with Heart Septal Defect

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Search GEO for disease gene expression data for Heart Septal Defect.

Pathways for genes affiliated with Heart Septal Defect

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GO Terms for genes affiliated with Heart Septal Defect

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Biological processes related to Heart Septal Defect according to GeneCards Suite gene sharing:

(show top 50)    (show all 52)
idNameGO IDScoreTop Affiliating Genes
1atrial cardiac muscle cell developmentGO:005501410.8NKX2-5, NKX2-6
2bundle of His developmentGO:000316610.8NKX2-5, TBX5
3cardiac ventricle morphogenesisGO:000320810.7GATA4, NKX2-5
4positive regulation of male gonad developmentGO:200002010.7CITED2, ZFPM2
5cardiac muscle tissue morphogenesisGO:005500810.6NKX2-5, TBX20
6endocardial cushion developmentGO:000319710.6CITED2, TBX5
7embryonic process involved in female pregnancyGO:006013610.6CITED2, NODAL
8nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetryGO:190016410.6CITED2, NODAL
9ventricular cardiac muscle cell developmentGO:005501510.6BMP10, NKX2-6
10positive regulation of vascular endothelial growth factor productionGO:001057510.6GATA4, NODAL
11trophectodermal cell differentiationGO:000182910.6CITED2, NODAL
12cardiac muscle cell proliferationGO:006003810.6BMP10, NKX2-5
13ventricular septum morphogenesisGO:006041210.5CITED2, ZFPM2
14positive regulation of cell-cell adhesionGO:002240910.5CITED2, NODAL
15pericardium developmentGO:006003910.5NKX2-6, TBX5
16embryonic placenta developmentGO:000189210.4CITED2, NODAL
17embryonic heart tube morphogenesisGO:000314310.4MESP1, TBX20
18ventricular septum developmentGO:000328110.4CITED2, GATA4, TBX5
19thyroid gland developmentGO:003087810.4NKX2-5, TBX1
20regulation of cardiac muscle contractionGO:005511710.3BMP10, NKX2-5
21outflow tract morphogenesisGO:000315110.3CITED2, NKX2-5, TBX20
22vasculature developmentGO:000194410.3CITED2, NODAL
23cardiac muscle tissue developmentGO:004873810.3GATA6, NKX2-5, ZFPM2
24atrial septum morphogenesisGO:006041310.2GATA4, NKX2-5, TBX20, TBX5
25activin receptor signaling pathwayGO:003292410.2ACVRL1, BMP10
26cell fate commitmentGO:004516510.2GATA4, GATA6, NODAL
27pharyngeal system developmentGO:006003710.2NKX2-5, NKX2-6, TBX1
28embryonic heart tube developmentGO:003505010.1NKX2-5, NKX2-6, NODAL, TBX20
29cell differentiationGO:003015410.1CITED2, NKX2-5, NKX2-6, ZFPM2
30positive regulation of BMP signaling pathwayGO:00305139.9ACVRL1, GATA4, GATA6
31positive regulation of cardiac muscle cell proliferationGO:00600459.9BMP10, GATA6, TBX20, TBX5
32transcription from RNA polymerase II promoterGO:00063669.9GATA4, GATA6, NKX2-5, TBX5
33regulation of transcription from RNA polymerase II promoterGO:00063579.9CITED2, NKX2-5, TBX1
34anatomical structure formation involved in morphogenesisGO:00486469.9GATA6, NODAL
35outflow tract septum morphogenesisGO:00031489.8GATA6, NKX2-5, TBX1, TBX20
36lung developmentGO:00303249.8NODAL, TBX5, ZFPM2
37cardiac muscle cell differentiationGO:00550079.8GATA4, GATA6, MESP1, NKX2-5, TBX5
38positive regulation of pathway-restricted SMAD protein phosphorylationGO:00108629.6ACVRL1, BMP10, NODAL
39liver developmentGO:00018899.6CITED2, GATA6, NODAL
40negative regulation of transcription, DNA-templatedGO:00458929.6CITED2, GATA6, MESP1, NKX2-5
41heart loopingGO:00019479.5CITED2, GATA4, MESP1, NKX2-5, NODAL, TBX20
42BMP signaling pathwayGO:00305099.5ACVRL1, BMP10, NKX2-5, NODAL
43in utero embryonic developmentGO:00017019.5ACVRL1, CITED2, GATA6, NODAL
44positive regulation of angiogenesisGO:00457669.3ACVRL1, GATA4, GATA6, NODAL
45negative regulation of cell migrationGO:00303369.2ACVRL1, BMP10, CITED2, TBX5
46negative regulation of transcription from RNA polymerase II promoterGO:00001229.1CITED2, GATA6, NKX2-5, NODAL, TBX20, ZFPM2
47regulation of transcription, DNA-templatedGO:00063558.8ACVRL1, CITED2, GATA6, TBX1, TBX20
48heart developmentGO:00075078.5BMP10, CITED2, NKX2-5, NKX2-6, NODAL, TBX1
49positive regulation of transcription, DNA-templatedGO:00458937.5ACVRL1, BMP10, CITED2, GATA4, GATA6, MESP1
50positive regulation of transcription from RNA polymerase II promoterGO:00459447.3ACVRL1, CITED2, GATA4, MESP1, NKX2-5, NODAL

Molecular functions related to Heart Septal Defect according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein kinase bindingGO:00199019.3ACVRL1, GATA4, TNNI3

Sources for Heart Septal Defect

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet