MCID: HRT011
MIFTS: 28

Heart Septal Defect malady

Cardiovascular diseases category

Summaries for Heart Septal Defect

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66Wikipedia, 34MalaCards
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Wikipedia:66 Heart septal defect refers to a congenital heart defect of one of the septa of the heart. more...

MalaCards: Heart Septal Defect, also known as septal defect, is related to tetralogy of fallot and atrial heart septal defect. An important gene associated with Heart Septal Defect is KCNJ13 (potassium inwardly-rectifying channel, subfamily J, member 13). Affiliated tissues include heart.

Aliases & Classifications for Heart Septal Defect

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9Disease Ontology, 46Novoseek, 63UMLS, 59SNOMED-CT, 41NCIt, 36MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Cardiovascular diseases


Aliases & Descriptions:

heart septal defect 9
septal defect 9 46
congenital septal defect of heart 9
cardiac septal defects 9
heart septal defects 63
septal defect nos 9


External Ids:

Disease Ontology9 DOID:1681
NCIt41 C84482
MeSH36 D006343

Related Diseases for Heart Septal Defect

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18GeneCards, 19GeneDecks
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Diseases related to Heart Septal Defect via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 500)
idRelated DiseaseScoreTop Affiliating Genes
1tetralogy of fallot31.1IPPK, NKX2-5, MEGF9
2atrial heart septal defect30.3IPPK, NKX2-5, MEGF9, KCNJ13, TLL1
3atrioventricular septal defect11.2
4pulmonary atresia with ventricular septal defect11.0
5double outlet right ventricle10.8
6transposition of the great arteries10.8
7multiple ventricular septal defects10.7
8aneurysm10.7
9left ventricular outflow tract obstruction10.7
10patent foramen ovale10.7
11patent ductus arteriosus10.7
12pulmonic stenosis10.6
13endocarditis10.6
14myocardial infarction10.6
15tricuspid atresia10.6
16cor triatriatum10.6
17dextrocardia10.6
18eisenmenger syndrome10.6
19aortic valve prolapse10.5
20aortic coarctation10.5
21aortopulmonary window10.5
22situs inversus10.5
23down syndrome10.5
24atrial septal defect sinus venosus10.5
25dandy-walker like malformation with atrioventricular septal defect10.5
26infective endocarditis10.5
27pulmonary valve stenosis10.5
28cleft mitral valve10.4
29atrial septal aneurysm10.4
30right bundle branch block10.4
31congenitally corrected transposition of the great arteries10.4
32atrial septal defect coronary sinus10.4
33atrial septal defect ostium primum10.4
34constrictive pericarditis10.4
35migraine10.4
36pericarditis10.4
37ventricular septal defect 110.4
38double-orifice mitral valve10.4
39right aortic arch10.4
40acute myocardial infarction10.3
41migraine with aura10.3
42holt-oram syndrome10.3
43aortic arch interruption10.3
44atrial septal defect 310.3
45atrioventricular septal defect 410.3
46cor triatriatum sinister10.3
47double outlet right ventricle with subaortic ventricular septal defect10.3
48atrioventricular block10.3
49lutembacher's syndrome10.3
50polydactyly10.3

Graphical network of the top 20 diseases related to Heart Septal Defect:



Diseases related to heart septal defect

Symptoms for Heart Septal Defect

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Drugs & Therapeutics for Heart Septal Defect

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Heart Septal Defect

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Anatomical Context for Heart Septal Defect

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34MalaCards
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MalaCards organs/tissues related to Heart Septal Defect:

34
Heart

Animal Models for Heart Septal Defect or affiliated genes

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Publications for Heart Septal Defect

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53PubMed
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Articles related to Heart Septal Defect:

idTitleAuthorsYear
1
Pulmonary arterial hypertension in adults born with a heart septal defect: the Euro Heart Survey on adult congenital heart disease. (17164490)
2007

Variations for Heart Septal Defect

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Expression for genes affiliated with Heart Septal Defect

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Heart Septal Defect

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Pathways for genes affiliated with Heart Septal Defect

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Compounds for genes affiliated with Heart Septal Defect

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GO Terms for genes affiliated with Heart Septal Defect

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17Gene Ontology
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Biological processes related to Heart Septal Defect according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cell differentiationGO:0301549.3NKX2-5, TLL1

Products for genes affiliated with Heart Septal Defect

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Heart Septal Defect

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet