MCID: HRT011
MIFTS: 40

Heart Septal Defect malady

Category: Cardiovascular diseases

Aliases & Classifications for Heart Septal Defect

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Aliases & Descriptions for Heart Septal Defect:

Name: Heart Septal Defect 11 13
Heart Septal Defects 39 68
Septal Defect 11 50
 
Congenital Septal Defect of Heart 11
Cardiac Septal Defects 11
Septal Defect Nos 11

Classifications:



External Ids:

Disease Ontology11 DOID:1681
ICD1030 Q21, Q21.9
MeSH39 D006343
NCIt45 C84482

Summaries for Heart Septal Defect

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Wikipedia:71 Heart septal defect refers to a congenital heart defect of one of the septa of the heart. more...

MalaCards based summary: Heart Septal Defect, also known as heart septal defects, is related to atrial heart septal defect and lymphedema, cardiac septal defects, and characteristic facies. An important gene associated with Heart Septal Defect is NKX2-5 (NK2 Homeobox 5), and among its related pathways are HOP Signaling and SRF and miRs in Smooth Muscle Differentiation and Proliferation. Affiliated tissues include heart, and related mouse phenotypes are digestive/alimentary and craniofacial.

Related Diseases for Heart Septal Defect

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Diseases related to Heart Septal Defect via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 48)
idRelated DiseaseScoreTop Affiliating Genes
1atrial heart septal defect12.3
2lymphedema, cardiac septal defects, and characteristic facies12.1
3severe hypotonia-psychomotor developmental delay-strabismus-cardiac septal defect syndrome12.0
4atrial septal defect 111.6
5atrial septal defect 411.6
6atrial septal defect 211.6
7atrial septal defect 311.6
8ventricular septal defect11.6
9atrial septal defect 611.5
10atrial septal defect 7, with or without av conduction defects11.5
11atrial septal defect 811.5
12atrial septal defect 511.5
13atrial septal defect 911.5
14hyperphosphatasia with mental retardation syndrome 211.0
15mitral regurgitation, conductive deafness, and fusion of cervical vertebrae and of carpal and tarsal bones10.9
16koolen-de vries syndrome10.8
17atrioventricular septal defect10.8
18right inferior vena cava connecting to left-sided atrium10.3CRELD1, GATA4
19left superior vena cava persisting to left-sided atrium10.3CRELD1, GATA4
20persistent eustachian valve10.2CRELD1, GATA4, GATA6
21congenital benign spinal muscular atrophy dominant10.2CRELD1, GATA4, GATA6
22pauciarticular chronic arthritis10.2CRELD1, GATA4, GATA6
23neuropathy, hereditary sensory and autonomic, type vi10.2CITED2, NKX2-5, TBX5
24congenital diarrhea 7 with exudative enteropathy10.2CFC1, GDF1, NKX2-6
25third-degree atrioventricular block10.2GATA4, NKX2-5, TBX5
26vulvar apocrine adenocarcinoma10.2CRELD1, GATA4, NKX2-6, TBX5
27mevalonic aciduria10.2CFC1, GDF1
28brachyolmia type 310.1NKX2-5, TBX1, TBX5
29fetal alcohol syndrome10.1GATA4, GATA6, NKX2-5, NKX2-6
30macroglossia10.1CRELD1, GATA4, GDF1, NKX2-5, NKX2-6
31vulvar sebaceous carcinoma10.1CRELD1, GATA4, GATA6, NKX2-6, TBX5
32prolidase deficiency10.1BMP10, GDF1
33skull base neoplasm10.1GATA4, GATA6, ZFPM2
34paget disease, extramammary10.0CRELD1, GDF1, NKX2-5, NKX2-6, ZFPM2
35pericardium disease10.0ACVRL1, CRELD1, GATA6, GDF1, NKX2-5, NKX2-6
36partial fetal alcohol syndrome9.9CRELD1, GATA4, GATA6, GDF1, NKX2-5, NKX2-6
37jmp syndrome9.9CFC1, GDF1, NODAL
38dentine erosion9.8CITED2, CLNK, GATA4, GATA6, NKX2-5, NKX2-6
39heart disease9.7
40optic nerve disease9.7ACVRL1, CLNK, CRELD1, GATA4, GATA6, GDF1
41malignant pineal area germ cell neoplasm9.7CITED2, GATA4, GATA6, GDF1, NKX2-5, NKX2-6
42floating-harbor syndrome9.6
43microcephaly9.6
44trichodental syndrome9.6CFC1, CRELD1, GATA4, GATA6, GDF1, NKX2-5
45xanthogranulomatous pyelonephritis9.6CFC1, GATA4, NKX2-5, NKX2-6, TBX1, TBX20
46ceroid lipofuscinosis, neuronal, 89.6CITED2, CRELD1, GATA4, GATA6, GDF1, NKX2-5
47hypogonadotropic hypogonadism 12 with or without anosmia9.0CFC1, CITED2, CRELD1, GATA4, GATA6, GDF1
48ichthyosis7.9ACVRL1, BMP10, CA5B, CFC1, CITED2, CLNK

Graphical network of the top 20 diseases related to Heart Septal Defect:



Diseases related to heart septal defect

Symptoms & Phenotypes for Heart Septal Defect

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MGI Mouse Phenotypes related to Heart Septal Defect according to GeneCards Suite gene sharing:

41 (show all 13)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053819.5ACVRL1, CITED2, GATA4, GDF1, NKX2-5, NODAL
2MP:00053829.2ACVRL1, CITED2, GDF1, MEF2C, NKX2-5, NODAL
3MP:00053719.1BMP10, CITED2, GATA4, GATA6, MEF2C, TBX1
4MP:00053978.0ACVRL1, BMP10, CITED2, CLNK, GATA4, GATA6
5MP:00053807.7ACVRL1, BMP10, CITED2, GATA4, GATA6, GDF1
6MP:00053697.3ACVRL1, BMP10, GATA4, GATA6, MEF2C, NKX2-5
7MP:00028737.2ACVRL1, BMP10, CITED2, GATA4, GATA6, GDF1
8MP:00053767.2ACVRL1, BMP10, CA5B, CITED2, GATA4, GATA6
9MP:00053847.1BMP10, CA5B, CITED2, GATA4, GATA6, GDF1
10MP:00053786.8ACVRL1, BMP10, CA5B, CITED2, GATA4, GATA6
11MP:00053856.8ACVRL1, BMP10, CITED2, GATA4, GATA6, GDF1
12MP:00053886.7ACVRL1, CITED2, GATA4, GATA6, GDF1, MEF2C
13MP:00107685.9ACVRL1, BMP10, CA5B, CITED2, GATA4, GATA6

Drugs & Therapeutics for Heart Septal Defect

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Drugs for Heart Septal Defect (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 124)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Oxycodoneapproved, illicit, investigationalPhase 437976-42-65284603
Synonyms:
(-)-14-Hydroxydihydrocodeinone
(-)-Oxycodone
(5alpha)-14-hydroxy-17-methyl-3-(methyloxy)-4,5-epoxymorphinan-6-one
124-90-3 (hydrochloride)
14-Hydroxydihydrocodeinone
14-hydroxy-3-methoxy-17-methyl-4,5alpha-epoxymorphinan-6-one
25333-72-6 (Terephthalate)
4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
4,5.alpha.-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
4,5alpha-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
4,5α-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
76-42-6
AC-16043
AC1Q4DTG
BRN 0043446
C08018
CHEBI:7852
CHEMBL656
CID5284603
Combunox
D05312
DB00497
DEA No. 9143
Dihydro-14-hydroxycodeinone
Dihydrohydroxycodeinone
Dihydrohydroxycondeinone
Dihydrone
Dihydroxycodeinone
Dinarkon
Diphydrone
EINECS 200-960-2
Endine (Australia)
Endocet
Endodan
Endone
Eubine
Eubine [France]
Eucodal
Eucodalum
Eukodal
Eutagen
HSDB 3142
Hydroxycodeinon
LS-92148
MolPort-004-285-989
Morphinan-6-one, 4,5alpha-epoxy-14-hydroxy-3-methoxy-17-methyl- (8CI)
NSC 19043
NSC19043
 
Ossicodone
Ossicodone [DCIT]
Oxanest
Oxicodona
Oxicodona [INN-Spanish]
Oxicon
Oxicone
Oxiconum
Oxikon
OxyFAST
OxyIR
OxyNorm
Oxycodeinon
Oxycodeinone
Oxycodon
Oxycodone
Oxycodone (USAN/INN)
Oxycodone Concentrate
Oxycodone Hcl
Oxycodone Hydrochloride
Oxycodone [USAN:INN:BAN]
Oxycodone hydrochloride
Oxycodonum
Oxycodonum [INN-Latin]
Oxycon
Oxycone
Oxycontin
Oxyfast
Oxynorm
PTI-821
Pancodine
Pancodone retard (United Kingdom)
Percobarb
Percodan
Percolone
Remoxy
Roxicet
Roxicodone
Supendol
Supendol [Canada]
Supeudol
Tecodin
Tekodin
Tekodin (free base)
Thecodine
Thekodin
Theocodin
UNII-CD35PMG570
WLN: T B6566 B6/CO 4ABBC R BX FV HO PN GHT&&TTJ CQ JO1 P1
oxycodone
2
WarfarinapprovedPhase 4, Phase 2, Phase 347081-81-26691, 54678486
Synonyms:
(-)-Warfarin
(S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone
(S)-Warfarin
(phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarin
(phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarine
1-(4'-Hydroxy-3'-coumarinyl)-1-phenyl-3-butanone
200 Coumarin
200 coumarin
3-(1'-Phenyl-2'-acetylethyl)-4-hydroxycoumarin
3-(Acetonylbenzyl)-4-hydroxycoumarin
3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin
3-(alpha-Phenyl-beta-acetylaethyl)-4-hydroxycumarin
3-(alpha-Phenyl-beta-acetylethyl)-4-hydroxycoumarin
4-Hydroxy-3- (3-oxo-1-fenyl-butyl) cumarine
4-Hydroxy-3- (3-oxo-1-phenyl-butyl)-cumarin
4-Hydroxy-3-(3-oxo-1-fenyl-butyl) cumarine
4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-cumarin
4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one
4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one
4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin
4-Idrossi-3- (3-oxo-)-fenil-butil)-cumarine
4-Idrossi-3-(3-oxo-)-fenil-butil)-cumarine
4-Idrossi-3-(3-oxo-1-fenil-butil)-cumarine
45706_FLUKA
45706_RIEDEL
4oh-coumarin deriv.
5543-56-6
5543-57-7
81-81-2
A2250_FLUKA
A2250_SIGMA
AC-15978
AC1L1N37
AC1Q6AN3
AR-1E2310
Arab Rat Death
Arab rat death
Arab rat deth
Athrombin
Athrombin-K
Athrombin-k
Athrombine-K
Athrombine-k
BRD-A24514565-001-02-2
BRD-A24514565-236-01-6
BRN 1293536
BSPBio_002026
Bio-0586
Brumolin
C01541
C19H16O4
CBDivE_002127
CBDivE_013236
CBKinase1_000192
CBKinase1_012592
CHEBI:10033
CHEMBL1464
CID6691
CO-Rax
Caswell No. 903
Choice
Choice (TN)
Co-Rax
Co-rax
Compound 42
Coumadin
Coumadin Tabs
Coumafen
Coumafene
Coumafene [French]
Coumaphen
Coumaphene
Coumarins
Coumefene
Cov-R-Tox
Cov-R-tox
D-Con
D08682
DB00682
DL-3-(alpha-acetonylbenzyl)-4-hydroxycoumarin
Dethmor
Dethnel
Dicusat E
Dicusat e
DivK1c_000444
EINECS 201-377-6
EINECS 226-907-3
EPA Pesticide Chemical Code 086002
Eastern states duocide
Fasco fascrat powder
Frass-Ratron
Frass-ratron
HMS1921K07
HMS2092C20
HMS501G06
HSDB 1786
I14-0958
IDI1_000444
Jantoven
KBio1_000444
KBio2_000674
KBio2_003242
KBio2_005810
KBio3_001526
KBioGR_000901
KBioSS_000674
Killgerm sewarin p
Kumader
Kumadu
Kumatox
Kypfarin
LS-55083
Latka 42
Latka 42 [Czech]
Liqua-tox
MLS001304042
Maag Rattentod Cum
Maag rattentod cum
Mar-Frin
Mar-frin
Marevan
Martin'S mar-frin
Martin's mar-frin
 
Maveran
MolPort-001-787-822
Mouse pak
NCGC00094810-01
NCGC00094810-02
NCGC00159398-03
NCGC00178855-01
NINDS_000444
NSC 59813
NSC59813
PS104_SUPELCO
Panwarfin
Place-Pax
Place-pax
Prothromadin
RAX
RCR grey squirrel killer concentrate
RCRA waste no. P001
Rat & mice bait
Rat and mice bait
Rat-B-gon
Rat-Gard
Rat-Kill
Rat-Mix
Rat-O-cide #2
Rat-O-cide no. 2
Rat-Ola
Rat-Trol
Rat-a-way
Rat-alpha-way
Rat-b-gon
Rat-beta-gon
Rat-gard
Rat-kill
Rat-mix
Rat-o-cide #2
Rat-ola
Rat-trol
Ratorex
Ratox
Ratoxin
Ratron
Ratron G
Ratron g
Rats-no-more
Ratten-Koederrohr
Ratten-koederrohr
Rattenstreupulver Neu Schacht
Rattenstreupulver neu schacht
Rattenstreupulver new schacht
Rattentraenke
Rattunal
Rcra waste number P001
Ro-Deth
Ro-deth
Rodafarin
Rodafarin C
Rodafarin c
Rodex
Rodex blox
Rosex
Rough & ready mouse mix
Rough and ready mouse mix
SMP1_000316
SMR000718754
SPBio_000870
SPECTRUM1500613
STK364490
Sakarat
Sewarin
Sofarin
Solfarin
Sorexa Plus
Sorexa plus
Spectrum2_000935
Spectrum3_000583
Spectrum4_000381
Spectrum5_001751
Spectrum_000194
Spray-trol brand roden-trol
Temus W
Temus w
Tintorane
Tox-Hid
Tox-hid
Twin light rat away
UNII-5Q7ZVV76EI
Vampirinip II
Vampirinip III
Vampirinip iii
W.A.R.F. 42
WARF compound 42
WLN: T66 BOVJ DYR&1V1 EQ
Waran
Warf 10
Warf 42
Warfarat
Warfarin (INN)
Warfarin (and salts of)
Warfarin Plus
Warfarin Q
Warfarin [BSI:ISO]
Warfarin [INN:BAN]
Warfarin plus
Warfarin plus [discontinued]
Warfarin sodium
Warfarin titrated to an INR of 2.5-3.0
Warfarin(R)
Warfarina
Warfarina [INN-Spanish]
Warfarine
Warfarine [INN-French]
Warfarine [ISO-French]
Warfarinum
Warfarinum [INN-Latin]
Warficide
Warfilone
Zoocoumarin
Zoocoumarin [Netherlands and USSR]
Zoocoumarin [Russian]
delta-Con
nchembio.307-comp19
rac-Warfarin
warfarin
3
Bupivacaineapproved, investigationalPhase 412332180-92-9, 38396-39-32474
Synonyms:
( inverted exclamation markA)-bupivacaine
(+-)-Bupivacaine
(1)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
(RS)-bupivacaine
(±)-bupivacaine
1-Butyl-2',6'-pipecoloxylidide
1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
15233-43-9
2180-92-9
38396-39-3
AB00053674
AC-2096
AC1L1DRE
AC1Q5LX4
AH 250
AKOS001637202
AR-1A0242
Anekain
BPBio1_000298
BRD-A01636364-003-05-2
BSPBio_000270
BSPBio_002607
Bio-0886
Bloqueina
Bucaine
Bucaine (TN)
Bupivacaina
Bupivacaina [INN-Spanish]
Bupivacaine (INN)
Bupivacaine Carbonate
Bupivacaine HCL
Bupivacaine HCL KIT
Bupivacaine Monohydrochloride, Monohydrate
Bupivacaine [INN:BAN]
Bupivacainum
Bupivacainum [INN-Latin]
Bupivan
C07529
C18H28N2O
CBupivacaine
CHEBI:3215
CHEMBL1098
CID2474
Carbostesin
D07552
DB00297
DL-Bupivacaine
DUR-843
 
DepoBupivacaine
DivK1c_000758
EINECS 218-553-3
EINECS 253-911-2
HMS2090F12
IDI1_000758
KBio1_000758
KBio2_002004
KBio2_004572
KBio2_007140
KBio3_001827
KBioGR_001516
KBioSS_002004
KST-1A4609
L000695
LAC-43
LS-109841
LS-2222
MLS001361336
Marcaina
Marcaine
Marcaine HCL
Marcaine Spinal
MolPort-004-955-820
NCGC00178579-01
NCGC00178579-02
NINDS_000758
NSC119660
Prestwick0_000305
Prestwick1_000305
Prestwick2_000305
Prestwick3_000305
SMR000058218
SPBio_001558
SPBio_002489
Sensorcaine
Sensorcaine-MPF
Sensorcaine-MPF Spinal
Spectrum2_001589
Spectrum3_000974
Spectrum4_001098
Spectrum5_001483
Spectrum_001524
Transdur-Bupivacaine
UNII-Y8335394RO
Win 11318
Win 11318 HCl
bupivacaine
cBupivacaine
dl-1-Butyl-2',6'-pipecoloxylidide
racemic bupivacaine
4
Epinephrineapproved, vet_approvedPhase 498551-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr.
Epipen Jr. Auto-Injector
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
Esphygmogenina
Exadrin
 
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
5
TiclopidineapprovedPhase 447155142-85-35472
Synonyms:
5-((2-Chlorophenyl)methyl)-4,5,6,7-tetrahydrothieno(3,2-c)pyridine
5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
5-[(2-chlorophenyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
5-[(2-chlorophenyl)methyl]-6,7-dihydro-4H-thieno[3,2-c]pyridine
55142-85-3
AC-15204
AC1L1KFB
BIDD:PXR0169
BPBio1_000191
BRD-K00603606-003-03-4
BRN 1216802
BSPBio_000173
C07140
C14H14ClNS
CAS-53885-35-1
CHEBI:9588
CHEMBL833
CID5472
D08594
DB00208
EINECS 259-498-5
HMS2089I18
L001108
LS-152434
MLS001201825
MolPort-002-507-849
 
NCGC00016872-01
NCGC00016872-02
NCGC00024361-04
PCR 5332
Prestwick0_000047
Prestwick1_000047
Prestwick2_000047
Prestwick3_000047
SMR000641861
SPBio_002094
STK589340
STOCK5S-54105
Ticlid
Ticlopidin-Puren
Ticlopidin-Puren (TN)
Ticlopidina
Ticlopidina [INN-Spanish]
Ticlopidine (INN)
Ticlopidine HCL
Ticlopidine Hydrochloride
Ticlopidine [INN:BAN]
Ticlopidinum
Ticlopidinum [INN-Latin]
UNII-OM90ZUW7M1
UNM-0000345023
ZINC19594599
ticlopidine
6
Aspirinapproved, vet_approvedPhase 4, Phase 2, Phase 3115250-78-22244
Synonyms:
11126-35-5
11126-37-7
1oxr
2-(Acetyloxy)benzoate
2-(Acetyloxy)benzoic acid
2-Acetoxybenzenecarboxylic acid
2-Acetoxybenzoate
2-Acetoxybenzoic acid
2-Carboxyphenyl acetate
2349-94-2
26914-13-6
50-78-2
8-hour Bayer
98201-60-6
A 5376
A.S.A
A.S.A.
A.S.A. Empirin
A.S.A. empirin
A2093_SIGMA
A3160_SIGMA
A5376_SIGMA
A6810_SIGMA
AB1003266
AC 5230
AC1L1D8U
AC1Q1LA0
ACETYLSALICYLIC ACID
AI3-02956
AIN
AKOS000118884
ASA
Acenterine
Acesal
Acetal
Acetard
Aceticyl
Acetilsalicilico
Acetilum acidulatum
Acetisal
Acetol
Acetonyl
Acetophen
Acetosal
Acetosalic acid
Acetosalin
Acetoxybenzoic acid
Acetylin
Acetylsal
Acetylsalicylate
Acetylsalicylic acid
Acetylsalicylsaeure
Acetylsalicylsaure
Acetylsalicylsäure
Acetylsalycilic acid
Acetyonyl
Acetysal
Acetysalicylic acid
Acide acetylsalicylique
Acido O-acetil-benzoico
Acido acetilsalicilico
Acidum acetylsalicylicum
Acimetten
Acisal
Acylpyrin
Adiro
Aloxiprimum
Asacard
Asagran
Asatard
Ascoden-30
Aspalon
Aspec
Aspergum
Aspir-Mox
Aspirdrops
Aspirin
Aspirin (JP15/USP)
Aspirin [BAN:JAN]
Aspirina 03
Aspirine
Asprin
Aspro
Aspro Clear
Asteric
Azetylsalizylsaeure
Azetylsalizylsäure
BIDD:GT0118
BRN 0779271
Bay-e-4465
Bayer
Bayer Aspirin 8 Hour
Bayer Buffered
Bayer Extra Strength Aspirin For Migraine Pain
Bayer Plus
Benaspir
Bi-prin
Bialpirina
Bialpirinia
Bufferin
C01405
CCRIS 3243
CHEBI:15365
CHEMBL25
CID2244
Caprin
Cardioaspirin
Cardioaspirina
Cemirit
Claradin
Clariprin
Colfarit
Contrheuma retard
Coricidin
Crystar
D00109
D001241
DB00945
Decaten
Delgesic
Dispril
DivK1c_000555
Dolean pH 8
Duramax
ECM
EINECS 200-064-1
EU-0100038
Easprin
Easprin (TN)
Ecolen
Ecotrin
Empirin
Empirin with Codeine
Endosprin
Endydol
Entericin
Enterophen
 
Enterosarein
Enterosarine
Entrophen
Extren
Globentyl
Globoid
HMS1920E13
HMS2090G03
HMS2091K13
HMS501L17
HSDB 652
Helicon
I14-7505
IDI1_000555
Idragin
Istopirin
KBio1_000555
KBio2_001725
KBio2_002271
KBio2_004293
KBio2_004839
KBio2_006861
KBio2_007407
KBio3_002149
KBio3_002751
KBioGR_000398
KBioGR_002271
KBioSS_001725
KBioSS_002272
Kapsazal
Kyselina 2-acetoxybenzoova
Kyselina acetylsalicylova
LS-143
Levius
Lopac-A-5376
Lopac0_000038
MLS001055329
MLS001066332
MLS001336045
MLS001336046
Magnecyl
Measurin
Medisyl
Micristin
MolPort-000-871-622
NCGC00015067-01
NCGC00015067-04
NCGC00015067-09
NCGC00090977-01
NCGC00090977-02
NCGC00090977-03
NCGC00090977-04
NCGC00090977-05
NCGC00090977-06
NCGC00090977-07
NCI60_002222
NINDS_000555
NSC 27223
NSC27223
NSC406186
Neuronika
Novid
Nu-seals
Nu-seals aspirin
O-(Acetyloxy)benzoate
O-(Acetyloxy)benzoic acid
O-Acetoxybenzoate
O-Acetoxybenzoic acid
O-Acetylsalicylic acid
O-Carboxyphenyl acetate
O-accetylsalicylic acid
O-acetylsalicylic acid
PL-2200
Persistin
Pharmacin
Pirseal
Polopirin
Polopiryna
Premaspin
R16CO5Y76E [UNII]
Rheumin tabletten
Rheumintabletten
Rhodine
Rhonal
Ronal
S-211
SMR000059138
SP 189
SPBio_001838
SPECTRUM1500130
ST075414
Salacetin
Salcetogen
Saletin
Salicylic acid acetate
Salicylic acid, acetate
Salospir
Solfrin
Solprin
Solprin acid
Solpyron
Solupsan
Spectrum2_001899
Spectrum3_001295
Spectrum4_000099
Spectrum5_000740
Spectrum_001245
Spira-Dine
St. Joseph
St. Joseph Aspirin for Adults
Supac
Tasprin
Temperal
Toldex
Triaminicin
Triple-sal
UNII R16CO5Y76E
UNII-R16CO5Y76E
UNII=R16CO5Y76E
UNM-0000306102
Vanquish
WLN: QVR BOV1
XAXA
Xaxa
Yasta
ZORprin
acide 2-(acétyloxy)benzoïque
acide acétylsalicylique
aspirin
cMAP_000006
component of Midol
component of Synirin
nchem.859-comp6
o-Acetoxybenzoic acid
o-Carboxyphenyl acetate
o-acetoxybenzoic acid
o-carboxyphenyl acetate
salicylic acid acetate
ácido acetilsalicílico
7
Dexmedetomidineapproved, vet_approvedPhase 4, Phase 3, Phase 159276631-46-4, 113775-47-668602, 5311068, 56032
Synonyms:
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
(+)-medetomidine
(S)-medetomidine
113775-47-6
4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
AC1NSJXT
C07450
CHEBI:4466
CHEMBL778
CID5311068
D00514
DEXMEDETOMIDINE
 
Dexdor (T)
Dexmedetomidin
Dexmedetomidina
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexmedetomidinum
Dexmédétomidine
MPV 1440
MPV-1440
Medetomidina [Spanish]
Medetomidine
Medetomidinum [Latin]
NCGC00025347-01
PRECEDEX
Precedex (TN)
Tocris-2023
ZINC04632106
8
Ketamineapproved, vet_approvedPhase 4, Phase 25696740-88-13821
Synonyms:
(+-)-Ketamine
(+/-)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone
(+/-)-2-(o-Chlorophenyl)-2-(methylamino)cyclohexanone
(+/-)-Ketamine
(-)-Ketamine
(S)-(-)-Ketamine
(S)-Ketamine
(±)-ketamine
100477-72-3
2-(2-Chloro-phenyl)-2-methylamino-cyclohexanone
2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone
2-(2-chlorophenyl)-2-(methylamino)cyclohexan-1-one
2-(Methylamino)-2-(2-chlorophenyl)cyclohexanone
2-(methylamino)-2-(2-chlorophenyl)cyclohexanone
2-(o-Chlorophenyl)-2-(methylamino)-cyclohexanone
2-(o-Chlorophenyl)-2-(methylamino)cyclohexanone
2-(o-chlorophenyl)-2-(methylamino)-cyclohexanone
33643-45-7
6740-88-1
79499-51-7
AC1L1GSH
AC1Q40UR
AKOS001053247
BRN 2216965
C07525
C13H16ClNO
CHEBI:138833
CHEBI:6121
CHEMBL742
CI 581 base
CI-581
CID3821
CLSTA 20
Calypsol
Cetamina
Cetamina [INN-Spanish]
Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)- (9CI)
Cyclohexanone, 2-(2-chlorophenyl)-2-(methylamino)-, (+-)- (9CI)
Cyclohexanone, 2-(o-chlorophenyl)-2-(methylamino)-, (+/-)- (8CI)
D08098
DB01221
 
DEA No. 7285
DL-ketamine
DivK1c_000217
EINECS 229-804-1
Esketamine
Green
IDI1_000217
KBio1_000217
KETAMINE HCL
Ketaject
Ketalar
Ketalar base
Ketamina
Ketamine (INN)
Ketamine Base
Ketamine HCL
Ketamine [INN:BAN]
Ketaminum
Ketaminum [INN-Latin]
Ketanest
Ketoject
Ketolar
Kétamine
L-Ketamine
LS-57301
MLS001331674
MolPort-001-838-070
NCGC00159480-02
NCGC00159480-03
NINDS_000217
NMDA
NSC 70151
NSC70151
SMR000238141
Special K
Special K [street name]
T385
Tekam
Tekam (TN)
UNII-690G0D6V8H
dl-Ketamine
ketamine
l-Ketamine
9
Propofolapproved, investigational, vet_approvedPhase 410822078-54-84943
Synonyms:
2, 6-Diisopropylphenol
2,6 Diisopropylphenol
2,6-Bis(1-methylethyl)phenol
2,6-Bis(Isopropyl)-phenol
2,6-DIISOPROPYLPHENOL
2,6-Diisopropyl phenol
2,6-Diisopropylphenol
2,6-bis(1-methylethyl)-phenol
2,6-di(propan-2-yl)phenol
2078-54-8
28449-97-0
4-06-00-03435 (Beilstein Handbook Reference)
50356-15-5
AB00513968
AC-2038
AC1L1J9Y
AC1Q1OUI
AI3-26295
AM-149
Abbott Brand of Propofol
Alpha Brand of Propofol
Ampofol
Aquafol
Astra Brand of Propofol
AstraZeneca Brand of Propofol
BIDD:GT0436
BPBio1_000950
BPBio1_000969
BRD-K82255054-001-03-5
BRN 1866484
BSPBio_000862
Biomol-NT_000248
Braun Brand of Propofol
C07523
C12H18O
CAS-2078-54-8
CCRIS 9000
CHEBI:44915
CHEMBL526
CID4943
CPD-11437
CPD000059151
Curamed Brand of Propofol
D00549
D015742
D0617
D126608
D126608_ALDRICH
DB00818
DDS-04F
Diisopropylphenol
Dipravan
Diprivan
Diprivan (TN)
Diprivan Injectable emulsion
Disoprivan
Disoprofol
EINECS 218-206-6
EU-0100437
Fresenius Brand of Propofol
Fresenius Kabi Brand of Propofol
Fresofol
HMS1570L04
HMS2089O21
HMS2094E17
 
HSDB 7123
ICI 35,868
ICI 35868
ICI-35,868
ICI-35868
ICI35,868
ICI35868
InChI=1/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H
Ivofol
Jsp004266
Juste Brand of Propofol
LS-996
Lopac-D126608
Lopac0_000437
MLS001066348
MLS001335999
MLS002454360
MolPort-001-794-517
NCGC00015389-01
NCGC00015389-02
NCGC00015389-04
NCGC00015389-09
NCGC00091538-01
NCGC00091538-02
NCGC00091538-03
NCGC00091538-04
NCGC00091538-05
NCGC00091538-06
NSC 5105
NSC5105
PFL
Parnell Brand of Propofol
Pisa Brand of Propofol
Prestwick0_000931
Prestwick1_000931
Prestwick2_000931
Prestwick3_000931
Propofol
Propofol (JAN/USAN/INN)
Propofol Abbott
Propofol Fresenius
Propofol IDD-D
Propofol MCT
Propofol Rovi
Propofol [USAN:INN:BAN]
Propofol(2,6-Diisopropylphenol)
Propofol-Lipuro
Propofolum
Propofolum [Latin]
Rapinovet
Recofol
Rovi Brand of Propofol
S01-0189
SAM002264610
SMR000059151
SPBio_003031
SPECTRUM1505022
ST50405911
Schering Brand of Propofol
UNII-YI7VU623SF
W505102_ALDRICH
ZD-0859
ZINC00968303
Zeneca Brand of Propofol
ghl.PD_Mitscher_leg0.558
nchembio.552-comp7
propofol
10
Clopidogrelapproved, nutraceuticalPhase 4, Phase 3, Phase 2778120202-66-6, 113665-84-260606
Synonyms:
( )-(S)-Clopidogrel
(+)-(S)-Clopidogrel
(+)-Clopidogrel
(S)-Clopidogrel
(S)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate
113665-84-2
AC-19024
AC1L1TKZ
AC1Q41I9
BIDD:GT0284
BRD-K27721098-065-02-9
BSPBio_003211
C16H16ClNO2S
CGE
CHEBI:37941
CHEMBL1771
CID60606
CLOPIDOGREL SULFATE
CPD000550475
Clopidogrel
Clopidogrel (INN)
Clopidogrel (TN)
Clopidogrel [BAN:INN]
Clopidogrel [Ban:Inn]
Clopidogrel [INN:BAN]
Clopidogrel bisulfate
Clopidogrel bisulphate
Clopidogrel sulfate
Clopidogrelum
D07729
DB00758
DivK1c_000787
HMS2090O21
HMS502H09
HSDB 7430
IDI1_000787
 
Isocover
KBio1_000787
KBio2_000545
KBio2_003113
KBio2_005681
KBio3_002431
KBioGR_000689
KBioSS_000545
LS-172232
MLS001165708
MLS001195633
MLS001304711
Methyl (+)-(S)-alpha-(o-chlorophenyl)-6,7-dihydrothieno(3,2-c)pyridine-5(4H)-acetate
MolPort-002-885-817
MolPort-003-845-991
NCGC00163329-02
NINDS_000787
Plavix
Plavix (TN)
SAM002589956
SMR000550475
SPBio_000463
SR 25990
STK580572
STOCK5S-27782
Spectrum2_000512
Spectrum3_001606
Spectrum4_000175
Spectrum_000105
TL8000400
UNII-A74586SNO7
Zyllt
clopidogrel
clopidogrel, (+)(S)-isomer
methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoate
methyl (2S)-2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate
nchem.651-comp8
11AnticoagulantsPhase 4, Phase 3, Phase 22623
12Anesthetics, LocalPhase 43492
13AnalgesicsPhase 4, Phase 2, Phase 3, Phase 111733
14CarticainePhase 427
15Central Nervous System DepressantsPhase 4, Phase 3, Phase 2, Phase 113403
16Epinephryl boratePhase 4985
17AnestheticsPhase 4, Phase 29596
18RacepinephrinePhase 4985
19Pharmaceutical SolutionsPhase 4, Phase 3, Phase 28192
20Chelating AgentsPhase 41423
21Purinergic P2Y Receptor AntagonistsPhase 4, Phase 2793
22Antirheumatic AgentsPhase 4, Phase 3, Phase 210956
23Anti-Inflammatory AgentsPhase 4, Phase 3, Phase 210729
24AntipyreticsPhase 4, Phase 2, Phase 31605
25Anti-Inflammatory Agents, Non-SteroidalPhase 4, Phase 3, Phase 24443
26Analgesics, Non-NarcoticPhase 4, Phase 2, Phase 3, Phase 16501
27Cyclooxygenase InhibitorsPhase 4, Phase 3, Phase 22870
28Cytochrome P-450 Enzyme InhibitorsPhase 43917
29Purinergic P2 Receptor AntagonistsPhase 4, Phase 2795
30Peripheral Nervous System AgentsPhase 4, Phase 2, Phase 3, Phase 123689
31Platelet Aggregation InhibitorsPhase 4, Phase 3, Phase 1, Phase 22516
32Neurotransmitter AgentsPhase 4, Phase 3, Phase 2, Phase 118340
33Fibrinolytic AgentsPhase 4, Phase 3, Phase 22388
34Excitatory Amino Acid AntagonistsPhase 4, Phase 21347
35Excitatory Amino AcidsPhase 4, Phase 21362
36Hypnotics and SedativesPhase 4, Phase 3, Phase 12616
37Anesthetics, IntravenousPhase 4, Phase 22538
38Adrenergic AgentsPhase 4, Phase 3, Phase 15352
39Anesthetics, GeneralPhase 4, Phase 22934
40Adrenergic alpha-2 Receptor AgonistsPhase 4, Phase 3, Phase 1980
41Adrenergic AgonistsPhase 4, Phase 3, Phase 13027
42Anesthetics, DissociativePhase 4, Phase 2544
43Adrenergic alpha-AgonistsPhase 4, Phase 3, Phase 11734
44Bronchodilator AgentsPhase 42965
45Tocolytic AgentsPhase 4739
46Autonomic AgentsPhase 410150
47Respiratory System AgentsPhase 44997
48AlbuterolPhase 4429
49Anti-Asthmatic AgentsPhase 43488
50Adrenergic beta-2 Receptor AgonistsPhase 4957

Interventional clinical trials:

(show top 50)    (show all 140)
idNameStatusNCT IDPhase
1Clopidogrel For the Prevention of New Onset Migraine Headache Following Transcatheter Closure of Atrial Septal DefectsUnknown statusNCT00799045Phase 4
2PC-Trial: Patent Foramen Ovale and Cryptogenic EmbolismUnknown statusNCT00166257Phase 4
3Comparison of the Local Anaesthetics Articaine and Bupivacaine in Treatment of Acute Sternum Pain After Heart SurgeryUnknown statusNCT01536717Phase 4
4Device Closure Versus Medical Therapy for Cryptogenic Stroke Patients With High-Risk Patent Foramen Ovale (DEFENSE-PFO)Unknown statusNCT01550588Phase 4
5Long-term Safety Study of the GORE® HELEX® Septal OccluderCompletedNCT00581308Phase 4
6Patent Foramen Ovale in Cryptogenic Stroke StudyCompletedNCT00697151Phase 4
7Comparative Effects of Dexmedetomidine and Ketofol for Sedation in Patients Undergoing Trans-esophageal EchocardiographyRecruitingNCT02867930Phase 4
8The Cardiopulmonary Effect of Inhaled Beta-2-agonists on Adult Patients Born With Ventricular Septum Defects.Not yet recruitingNCT02914652Phase 4
9Endoscopic Closure of Tracheoesophageal Fistulas With Occluder DeviceTerminatedNCT01153061Phase 4
10Mesh Ablator Versus Cryoballoon Pulmonary Vein Ablation of Symptomatic Paroxysmal Atrial FibrillationTerminatedNCT01061931Phase 4
11MIST II PFO-Migraine Trial With BioSTAR® Bioabsorbable Septal Repair ImplantUnknown statusNCT00283738Phase 2, Phase 3
12Evaluation of the STARFlex® Septal Closure System in Patients With a Stroke or TIA Due to the Possible Passage of a Clot of Unknown Origin Through a Patent Foramen Ovale (PFO)Unknown statusNCT00201461Phase 2, Phase 3
13Bosentan for Mild Pulmonary Vascular Disease in Asd Patients.CompletedNCT01218607Phase 3
14The Pharmacology and Hemodynamics of Dexmedetomidine in Children With Congenital Heart DiseaseCompletedNCT00480740Phase 3
15Concomitant Utilization of Radio Frequency Energy for Atrial Fibrillation (CURE-AF) StudyCompletedNCT00431834Phase 3
16Medtronic Concomitant Utilization of Radio Frequency for Atrial Fibrillation CURE-AF/PersistentCompletedNCT00506493Phase 3
17Infant Heart Surgery: Central Nervous System Sequelae of Circulatory ArrestCompletedNCT00000470Phase 3
18Patent Foramen Ovale Closure or Anticoagulants Versus Antiplatelet Therapy to Prevent Stroke RecurrenceCompletedNCT00562289Phase 3
19Minimally Invasive Transthoracic Device Closure in Perimembranous Ventricular Septal DefectRecruitingNCT02644330Phase 2, Phase 3
20GORE® HELEX® Septal Occluder / GORE® Septal Occluder for Patent Foramen Ovale (PFO) Closure in Stroke Patients - The Gore REDUCE Clinical StudyActive, not recruitingNCT00738894Phase 3
21Safety and Effectiveness of the Nit-Occlud® Lê VSD Spiral Coil SystemSuspendedNCT00390702Phase 2, Phase 3
22ESCAPE Migraine TrialTerminatedNCT00267371Phase 3
23Right to Left Cardiac Shunt DetectionTerminatedNCT01773252Phase 3
24Angiotensin Converting Enzyme Inhibition in Children With Mitral RegurgitationTerminatedNCT00113698Phase 3
25Cardiox Shunt Detection Technology StudyTerminatedNCT01333761Phase 3
26Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery : Revised ProtocolCompletedNCT01120964Phase 1, Phase 2
27Use of Ketamine Prior to Cardiopulmonary Bypass in ChildrenCompletedNCT00556361Phase 2
28Oral Sildenafil and Intravenous Milrinone on Postoperative Pulmonary HypertensionCompletedNCT02595541Phase 1, Phase 2
29Hypertonic Saline Dextran in Pediatric Cardiac SurgeryCompletedNCT00199771Phase 2
30Premium Migraine TrialCompletedNCT00355056Phase 2
31Feasibility Trial of the DC Devices Interatrial Septal Device (IASD) SystemCompletedNCT01570517Phase 1, Phase 2
32Intra-Cardiac Echocardiography Guided Cardioversion(ICE-CHIP) StudyCompletedNCT00281073Phase 1, Phase 2
33Left Ventricular Septum Pacing in Patients by Transvenous Approach Through the Inter-ventricular SeptumCompletedNCT01609738Phase 1, Phase 2
34Precutaneous High Risk Patent Foramen Ovale to Treat Migraine HeadachesNot yet recruitingNCT02777359Phase 2
35Mesoblast Stem Cell Therapy for Patients With Single Ventricle and Borderline Left VentricleNot yet recruitingNCT03079401Phase 1, Phase 2
36Catheter Thrombectomy in Patients With Massive Pulmonary EmbolismTerminatedNCT00314002Phase 1, Phase 2
37PRIMA PFO Migraine TrialTerminatedNCT00505570Phase 2
38Patients With Patent Foramen Ovale and Endocardial Device Leads on Apixaban for Prevention of Paradoxical EmboliWithdrawnNCT02378623Phase 2
39Aberrations in Carnitine Homeostasis in Congenital Heart Disease With Increased Pulmonary Blood FlowUnknown statusNCT01825369Phase 1
40Closure of Muscular Ventricular Septal Defects With The AMPLATZER® Muscular VSD OccluderUnknown statusNCT00583791Phase 1
41Closure of Perimembranous Ventricular Septal Defects With The AMPLATZER® Membranous VSD OCCLUDERCompletedNCT00578708Phase 1
42A Phase I Study of Dexmedetomidine Bolus and Infusion in Corrective Infant Cardiac Surgery: Safety and PharmacokineticsRecruitingNCT01915277Phase 1
43Radiation-Free Heart Catheterization Using MRIRecruitingNCT02739087Phase 1
44Transcaval Access for Transcatheter Aortic Valve Replacement in People With No Good Options for Aortic AccessEnrolling by invitationNCT02280824Phase 1
45Study of Energy Expenditure in Infants With Ventricular Septal DefectsUnknown statusNCT00006272
46Aortic Regurgitation After Surgical Repair of Outlet-Type Ventricular Septal DefectUnknown statusNCT00173186
47Study of Blood Clotting After Transcatheter Atrial Septal Defect ClosureUnknown statusNCT01086046
48Closure of Atrial Septal Defects With the AMPLATZER Septal Occluder - Post Approval StudyUnknown statusNCT00650936
49InterSEPT: In‐Tunnel SeptRx European PFO TrialUnknown statusNCT01385670
50Influence of Position on Detection of Patent Foramen Ovale by Simultaneous Transesophageal Echo and Transcranial DopplerUnknown statusNCT02383836

Search NIH Clinical Center for Heart Septal Defect


Cochrane evidence based reviews: heart septal defects

Genetic Tests for Heart Septal Defect

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Anatomical Context for Heart Septal Defect

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MalaCards organs/tissues related to Heart Septal Defect:

36
Heart

Publications for Heart Septal Defect

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Articles related to Heart Septal Defect:

idTitleAuthorsYear
1
Pulmonary arterial hypertension in adults born with a heart septal defect: the Euro Heart Survey on adult congenital heart disease. (17164490)
2007

Variations for Heart Septal Defect

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Copy number variations for Heart Septal Defect from CNVD:

6 (show all 28)
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1161575221940537520797502DeletionAIFM3cardiac septal defect
2161576221940537520797502DeletionCCDC116cardiac septal defect
3161577221940537520797502DeletionCRKLcardiac septal defect
4161578221940537520797502DeletionFLJ42953cardiac septal defect
5161579221940537520797502DeletionGGT-2cardiac septal defect
6161580221940537520797502DeletionHIC2cardiac septal defect
7161581221940537520797502DeletionLOC150223cardiac septal defect
8161582221940537520797502DeletionLOC220686cardiac septal defect
9161583221940537520797502DeletionLOC400891cardiac septal defect
10161584221940537520797502DeletionLZTR1cardiac septal defect
11161585221940537520797502DeletionMAPK1cardiac septal defect
12161586221940537520797502DeletionMGC16703cardiac septal defect
13161587221940537520797502DeletionP2RXL1cardiac septal defect
14161588221940537520797502DeletionPIKA4CAcardiac septal defect
15161589221940537520797502DeletionPPIL2cardiac septal defect
16161590221940537520797502DeletionPPM1Fcardiac septal defect
17161591221940537520797502DeletionRBP3.2cardiac septal defect
18161592221940537520797502DeletionRBP3.3cardiac septal defect
19161593221940537520797502DeletionSDF2L1cardiac septal defect
20161594221940537520797502DeletionSERPIND1cardiac septal defect
21161595221940537520797502DeletionSLC7A4cardiac septal defect
22161596221940537520797502DeletionSNAP29cardiac septal defect
23161597221940537520797502DeletionTHAP7cardiac septal defect
24161598221940537520797502DeletionTOP3Bcardiac septal defect
25161599221940537520797502DeletionUBE2L3cardiac septal defect
26161600221940537520797502DeletionYPEL1cardiac septal defect
27161601221940537520797502Deletionmir-130bcardiac septal defect
28161602221940537520797502Deletionmir-301bcardiac septal defect

Expression for genes affiliated with Heart Septal Defect

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Search GEO for disease gene expression data for Heart Septal Defect.

Pathways for genes affiliated with Heart Septal Defect

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Pathways related to Heart Septal Defect according to GeneCards Suite gene sharing:

(show all 12)
idSuper pathwaysScoreTop Affiliating Genes
110.1GATA4, NKX2-5
29.8MEF2C, NKX2-5
3
Show member pathways
9.6CFC1, GDF1, NODAL
4
Show member pathways
9.5ACVRL1, GATA4, GATA6, NKX2-5
5
Show member pathways
9.5GATA4, MEF2C, NKX2-5, TBX5
6
Show member pathways
9.3GATA4, GATA6, NODAL, TBX1
79.2BMP10, GATA4, MEF2C, NKX2-5
88.8GATA4, MEF2C, NKX2-5, TBX5, TNNI3
9
Show member pathways
8.8BMP10, CFC1, GATA4, MEF2C, NKX2-5, TBX5
108.5GATA4, MEF2C, NKX2-5, NODAL, TBX5, TNNI3
118.3GATA4, MEF2C, NKX2-5, NODAL, TBX20, TBX5
128.1BMP10, GATA4, GATA6, MEF2C, NKX2-5, TBX1

GO Terms for genes affiliated with Heart Septal Defect

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Biological processes related to Heart Septal Defect according to GeneCards Suite gene sharing:

(show top 50)    (show all 60)
idNameGO IDScoreTop Affiliating Genes
1cardiac ventricle morphogenesisGO:000320810.9GATA4, NKX2-5
2bundle of His developmentGO:000316610.9NKX2-5, TBX5
3atrial cardiac muscle cell developmentGO:005501410.9NKX2-5, NKX2-6
4cardiac muscle tissue morphogenesisGO:005500810.9NKX2-5, TBX20
5pericardium developmentGO:006003910.9NKX2-6, TBX5
6cardiac right ventricle morphogenesisGO:000321510.9GATA4, TBX20
7embryonic heart tube left/right pattern formationGO:006097110.9CITED2, NKX2-5
8cardiac septum developmentGO:000327910.9CRELD1, TBX20
9intestinal epithelial cell differentiationGO:006057510.8GATA4, GATA6
10right ventricular cardiac muscle tissue morphogenesisGO:000322110.8NKX2-5, ZFPM2
11positive regulation of male gonad developmentGO:200002010.8CITED2, ZFPM2
12endocardial cushion morphogenesisGO:000320310.8ACVRL1, TBX20
13adult heart developmentGO:000751210.7BMP10, NKX2-5
14cardiac muscle cell proliferationGO:006003810.7BMP10, NKX2-5
15heart trabecula formationGO:006034710.7BMP10, NKX2-5
16endocardial cushion developmentGO:000319710.7CRELD1, GATA4, TBX5
17nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetryGO:190016410.7CITED2, NODAL
18positive regulation of cell-cell adhesionGO:002240910.7CITED2, NODAL
19regulation of cardiac muscle contractionGO:005511710.7BMP10, NKX2-5
20nodal signaling pathwayGO:003809210.7CFC1, NODAL
21cardiac ventricle formationGO:000321110.7MEF2C, NKX2-5
22activin receptor signaling pathwayGO:003292410.6ACVRL1, BMP10
23negative regulation of endothelial cell migrationGO:001059610.6ACVRL1, BMP10
24cardiac muscle hypertrophy in response to stressGO:001489810.5GATA6, MEF2C
25cardiac muscle tissue developmentGO:004873810.5GATA6, NKX2-5, ZFPM2
26pharyngeal system developmentGO:006003710.5NKX2-5, NKX2-6, TBX1
27atrial septum morphogenesisGO:006041310.5GATA4, NKX2-5, TBX20, TBX5
28heart contractionGO:006004710.5NKX2-5, TNNI3
29smooth muscle cell differentiationGO:005114510.5GATA6, MEF2C
30lung developmentGO:003032410.5NODAL, TBX5, ZFPM2
31positive regulation of BMP signaling pathwayGO:003051310.5ACVRL1, GATA4, GATA6
32embryonic viscerocranium morphogenesisGO:004870310.5MEF2C, TBX1
33positive regulation of cardioblast differentiationGO:005189110.4GATA4, GATA6, NKX2-5, TBX5
34liver developmentGO:000188910.4CITED2, GATA6, NODAL
35transdifferentiationGO:006029010.4GATA4, MEF2C
36embryonic heart tube developmentGO:003505010.3NKX2-5, NKX2-6, NODAL, TBX20
37SMAD protein signal transductionGO:006039510.3BMP10, GDF1, NODAL
38positive regulation of angiogenesisGO:004576610.1ACVRL1, GATA4, GATA6, NODAL
39negative regulation of cell migrationGO:003033610.1ACVRL1, BMP10, CITED2, TBX5
40ventricular cardiac muscle cell developmentGO:005501510.1BMP10, NKX2-5, NKX2-6
41determination of left/right symmetryGO:000736810.1CFC1, CITED2, NODAL, TBX1
42negative regulation of transcription, DNA-templatedGO:004589210.1CITED2, GATA6, NKX2-5, TBX20, ZFPM2
43in utero embryonic developmentGO:000170110.1ACVRL1, GATA6, NODAL, ZFPM2
44positive regulation of pathway-restricted SMAD protein phosphorylationGO:001086210.0ACVRL1, BMP10, GDF1, NODAL
45cardiac muscle cell differentiationGO:005500710.0GATA4, GATA6, MEF2C, NKX2-5, TBX5
46outflow tract septum morphogenesisGO:00031489.9GATA6, NKX2-5, TBX1, TBX20, ZFPM2
47heart loopingGO:00019479.9GATA4, MEF2C, NKX2-5, NODAL, TBX20
48BMP signaling pathwayGO:00305099.8ACVRL1, BMP10, GDF1, NKX2-5, NODAL
49vasculogenesisGO:00015709.8NKX2-5, TNNI3, ZFPM2
50outflow tract morphogenesisGO:00031519.8CITED2, MEF2C, NKX2-5, TBX1, TBX20

Molecular functions related to Heart Septal Defect according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1RNA polymerase II transcription coactivator activityGO:000110510.5CITED2, TBX20, ZFPM2
2transcription factor activity, RNA polymerase II distal enhancer sequence-specific bindingGO:000370510.3GATA6, MEF2C, NKX2-5
3RNA polymerase II transcription factor bindingGO:000108510.2GATA4, GATA6, TBX20, ZFPM2
4transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific bindingGO:000122810.1GATA4, GATA6, NKX2-5, TBX5
5transcription factor bindingGO:000813410.0GATA4, GATA6, NKX2-5, TBX5, ZFPM2
6transcription regulatory region DNA bindingGO:00442129.9GATA4, GATA6, MEF2C, NKX2-5
7chromatin bindingGO:00036829.9CITED2, GATA4, GATA6, MEF2C, NKX2-5
8RNA polymerase II regulatory region sequence-specific DNA bindingGO:00009779.9GATA4, GATA6, MEF2C, TBX20, TBX5
9transforming growth factor beta receptor bindingGO:00051609.5BMP10, GDF1, NODAL
10sequence-specific DNA bindingGO:00435659.3GATA4, GATA6, MEF2C, NKX2-5, NKX2-6, TBX1
11transcription factor activity, sequence-specific DNA bindingGO:00037008.8CITED2, GATA4, GATA6, MEF2C, NKX2-5, NKX2-6

Sources for Heart Septal Defect

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet