Aliases & Classifications for Heart Tumor

MalaCards integrated aliases for Heart Tumor:

Name: Heart Tumor 50 52
Primary Cardiac Tumors, Childhood 50
Intracavitary Tumors of the Heart 69
Neoplasm of Myocardium 69
Intracavitary Tumors 50
Myocardial Tumors 50
Heart Neoplasm 69

Classifications:



Summaries for Heart Tumor

MalaCards based summary : Heart Tumor, also known as primary cardiac tumors, childhood, is related to primary pediatric heart tumor and primary adult heart tumor. An important gene associated with Heart Tumor is CCL26 (C-C Motif Chemokine Ligand 26), and among its related pathways/superpathways are Jak-STAT signaling pathway (KEGG) and IL-2 Signaling Pathway. The drugs Cyclophosphamide and Doxorubicin have been mentioned in the context of this disorder. Affiliated tissues include lung, heart and prostate, and related phenotype is Increased shRNA abundance (Z-score > 2).

Related Diseases for Heart Tumor

Diseases in the Heart Tumor family:

Primary Adult Heart Tumor

Diseases related to Heart Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
id Related Disease Score Top Affiliating Genes
1 primary pediatric heart tumor 11.8
2 primary adult heart tumor 11.8
3 myocardium cancer 10.8
4 blake pouch cyst 9.8 BCL2 IL2RB
5 oral antidiabetic drugs toxicity or dose selection 9.8 BCL2 PTCH1
6 smoking as a quantitative trait locus 1 9.8 BCL2 IL2RB
7 seminoma 9.6
8 testicular seminoma 9.6
9 dilated cardiomyopathy 9.6
10 cardiomyopathy 9.6
11 small cell sarcoma 9.6 BCL2 PTCH1
12 pierre robin syndrome 9.4
13 cardiac arrest 9.4
14 fibrosarcoma 9.4
15 syncope 9.4
16 hemeralopia, congenital essential 8.0 ANG BCL2 CCL26 IL2RB PTCH1

Graphical network of the top 20 diseases related to Heart Tumor:



Diseases related to Heart Tumor

Symptoms & Phenotypes for Heart Tumor

GenomeRNAi Phenotypes related to Heart Tumor according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.62 PTCH1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-11 9.62 CCL26
3 Increased shRNA abundance (Z-score > 2) GR00366-A-113 9.62 CCL26
4 Increased shRNA abundance (Z-score > 2) GR00366-A-114 9.62 IL2RB
5 Increased shRNA abundance (Z-score > 2) GR00366-A-156 9.62 CCL26
6 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.62 CCL26
7 Increased shRNA abundance (Z-score > 2) GR00366-A-166 9.62 CCL26
8 Increased shRNA abundance (Z-score > 2) GR00366-A-186 9.62 CCL26
9 Increased shRNA abundance (Z-score > 2) GR00366-A-19 9.62 PTCH1
10 Increased shRNA abundance (Z-score > 2) GR00366-A-202 9.62 PTCH1
11 Increased shRNA abundance (Z-score > 2) GR00366-A-214 9.62 IL2RB
12 Increased shRNA abundance (Z-score > 2) GR00366-A-46 9.62 IL2RB
13 Increased shRNA abundance (Z-score > 2) GR00366-A-5 9.62 IL2RB
14 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.62 CCL26 IL2RB PTCH1
15 Increased shRNA abundance (Z-score > 2) GR00366-A-7 9.62 CCL26
16 Increased shRNA abundance (Z-score > 2) GR00366-A-79 9.62 CCL26 PTCH1
17 Increased shRNA abundance (Z-score > 2) GR00366-A-93 9.62 CCL26

Drugs & Therapeutics for Heart Tumor

Drugs for Heart Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 887)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cyclophosphamide Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 50-18-0, 6055-19-2 2907
2
Doxorubicin Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 23214-92-8 31703
3
Epirubicin Approved Phase 4,Phase 3,Phase 2,Phase 1 56420-45-2 41867
4
Fluorouracil Approved Phase 4,Phase 3,Phase 2,Phase 1 51-21-8 3385
5
Amiodarone Approved, Investigational Phase 4,Phase 3 1951-25-3 2157
6
Menthol Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 2216-51-5 16666
7
Cetuximab Approved Phase 4,Phase 3,Phase 2 205923-56-4 56842117 2333
8
Amiloride Approved Phase 4 2016-88-8, 2609-46-3 16231
9
Amlodipine Approved Phase 4 88150-42-9 2162
10
Simvastatin Approved Phase 4,Phase 3,Phase 2 79902-63-9 54454
11
Telmisartan Approved, Investigational Phase 4 144701-48-4 65999
12
Ropivacaine Approved Phase 4,Phase 3 84057-95-4 71273 175805
13
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-28-2 5757
14
Medroxyprogesterone acetate Approved, Investigational Phase 4,Phase 3 71-58-9
15
Progesterone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 57-83-0 5994
16
Acarbose Approved, Investigational Phase 4 56180-94-0 441184
17
Pioglitazone Approved, Investigational Phase 4,Phase 2 111025-46-8 4829
18
Benzocaine Approved Phase 4,Phase 3,Phase 2,Phase 1 1994-09-7, 94-09-7 2337
19
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
20
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2 51-43-4 5816
21 Racepinephrine Approved Phase 4,Phase 3,Phase 2
22
Tamoxifen Approved Phase 4,Phase 3,Phase 2,Phase 1 10540-29-1 2733526
23
Dobutamine Approved Phase 4,Phase 3 34368-04-2 36811
24
Norepinephrine Approved Phase 4,Phase 3 51-41-2 439260
25
Enalapril Approved, Vet_approved Phase 4,Phase 3,Phase 2 75847-73-3 5362032 40466924
26
Enalaprilat Approved Phase 4,Phase 3,Phase 2 76420-72-9 6917719
27
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 2,Phase 3 76631-46-4, 113775-47-6 68602 5311068 56032
28
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 1,Phase 2 2078-54-8 4943
29
Cisplatin Approved Phase 4,Phase 3,Phase 2,Phase 1 15663-27-1 84093 441203 2767
30
Dopamine Approved Phase 4,Phase 3,Phase 1,Phase 2,Early Phase 1 51-61-6, 62-31-7 681
31
Everolimus Approved Phase 4,Phase 3,Phase 1,Phase 2 159351-69-6 6442177
32
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
33
Mycophenolate mofetil Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 128794-94-5 5281078
34
Mycophenolic acid Approved Phase 4,Phase 3,Phase 2,Phase 1 24280-93-1 446541
35
Sirolimus Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 53123-88-9 5284616 6436030 46835353
36
Etanercept Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 185243-69-0
37
Iron Approved Phase 4,Phase 3,Phase 2 7439-89-6 23925
38
Aprepitant Approved, Investigational Phase 4,Phase 3,Phase 2 170729-80-3 151165 6918365
39
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-02-2 5743
40
Fosaprepitant Approved Phase 4,Phase 3,Phase 2 172673-20-0 219090
41 Ramosetron Approved Phase 4,Phase 2 132036-88-5
42
Carboplatin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 41575-94-4 10339178 498142 38904
43
Paclitaxel Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 33069-62-4 36314
44
Trastuzumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 180288-69-1 9903
45
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1 1959-05-2, 59-05-2 126941
46
Bleomycin Approved Phase 4,Phase 3,Phase 2 11056-06-7 5360373
47
Dacarbazine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 4342-03-4 5351166
48
Etoposide Approved Phase 4,Phase 3,Phase 2,Phase 1 33419-42-0 36462
49
rituximab Approved Phase 4,Phase 3,Phase 2,Phase 1 174722-31-7 10201696
50
Vincristine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 2068-78-2, 57-22-7 5978

Interventional clinical trials:

(show top 50) (show all 2259)

id Name Status NCT ID Phase Drugs
1 A Study of Liposomal Doxorubicin in Women With Breast Cancer Exploiting Tissue Doppler Imaging Unknown status NCT00531973 Phase 4 liposomal doxorubicin;epirubicin
2 Amiodarone Prophylaxis for Atrial Fibrillation in Patients Undergoing Surgery for Lung Cancer Unknown status NCT00724581 Phase 4 Amiodarone
3 Endoesophageal Cryotherapy For Ablating Barrett's Esophagus and Early Stage Esophageal Cancer Unknown status NCT00628784 Phase 4
4 HOPE-2 Study (Heart Outcomes Prevention Evaluation-2 Study) Unknown status NCT00106886 Phase 4 Folic acid, vitamin B6 and B12 or placebo
5 Study Effects of Ginkgo Biloba Extract on Endothelial Cell Function and Genetic Effects on the Response to Ginkgo Biloba Extract in Diabetic Patients With Stable Coronary Artery Disease Unknown status NCT01038050 Phase 4 Ginkgo Biloba Extract (GBE)
6 Cetuximab Compared to Mitomycin-C and 5-Fluorouracil for Locally Advanced Squamous Cell Carcinomas of the Head and Neck Unknown status NCT02015650 Phase 4 Cetuximab;Mitomycin-C/ 5-Fluorouracil
7 Effects of Angiotensin II Receptor Blocker Compared With Diuretics in High-risk Hypertensive Patients Unknown status NCT01011660 Phase 4 Amlodipine, Telmisartan, Amiloride Compound , Simvastatin
8 The ACT-OUT Trial: ACTivity OUTcomes Based on High Carbohydrate or High Fat Diet in Metabolic Syndrome Unknown status NCT01357382 Phase 4
9 Comparison the Level of CTGF Protein and Related Cytokine in Pleural Effusion Unknown status NCT00313066 Phase 4
10 Prevention of Myocardial Dysfunction and Injury Resulting From Salter Innominate Osteotomy by Caudal Block Unknown status NCT02144766 Phase 4 ropivacaine;saline
11 Multi-centre Clinical Trial on Hormone Replacement Treatment in China Unknown status NCT01698164 Phase 4 estradiol plus MPA;Ximingting Tablet;estradiol plus progesterone
12 Thiazolidinedione (TZD) on the Diabetic Retinopathy and Nephropathy Unknown status NCT01175486 Phase 4 Actos (Pioglitazone);Acarbose
13 Influence of Profound Muscle Relaxation on Muscle Trauma and Postoperative Pulmonary Function Unknown status NCT01804933 Phase 4 profound neuromuscular blockade
14 Cardiac Arrhythmias in Patients Undergoing Kidney Cancer Surgery Depending on the Anaesthesia Method Completed NCT02988219 Phase 4 Bupivacaine-fentanyl
15 Study to Monitor the Effects of Androgen Suppression Treatment on the Heart Completed NCT01230905 Phase 4
16 Liver Safety Under Upfront Arimidex vs Tamoxifen Completed NCT00537771 Phase 4 Anastrozole;Tamoxifen
17 A Study in Cancer Patients to Evaluate the Effect of Lapatinib on the QTc Interval Completed NCT01328054 Phase 4 lapatinib;placebo matching lapatinib
18 Eszopiclone and Inflammatory Mediators in Patients With Acute Coronary Syndrome Completed NCT00822679 Phase 4 Eszopiclone
19 Anti-Inflammatory Actions of Valsartan in Patients With Type 2 Diabetes Mellitus Completed NCT00982358 Phase 4 Valsartan
20 Ulinastatin's Anti-inflammatory Reaction in Cardiac Surgery Completed NCT01518569 Phase 4 ulinastatin;placebo
21 Decreasing Postoperative Complications by Goal-Directed Fluid Therapy During Esophageal Resection Completed NCT01416077 Phase 4
22 Evaluation of Arterial Pressure Based Cardiac Output for Goal-Directed Perioperative Therapy Completed NCT00526331 Phase 4
23 Prevention of Chemotherapy-induced Cardiotoxicity in High-risk Patients Completed NCT00292526 Phase 4 Enalapril
24 Comparison of Hemodynamics Between Dexmedetomidine and Propofol for Sedation in Patients With Abdominal Surgery Completed NCT02393066 Phase 4 Propofol;Dexmedetomidine
25 Breast VCEUS to Evaluate Early Response to Neoadjuvant Chemotherapy Completed NCT01817374 Phase 4 Definity (Perflutren Lipid Microspheres)
26 Hemodynamic Stability of Bupivacaine With and Without Adrenaline for Paracervical Block for Cervical Conization Completed NCT02368054 Phase 4 Bupivacaine;Adrenaline
27 Scalp Nerve Block and Opioid Consumption in Brain Surgery Completed NCT02057367 Phase 4 Scalp block with 0.5% plain Marcaine;Scalp block with 0.9% normal saline
28 Radical Prostatectomy and Perioperative Fluid Therapy Completed NCT00771966 Phase 4
29 An Alternative to A Fixed Schedule In Management Of Prostate Cancer Completed NCT01056562 Phase 4
30 A Study of Patients With HER2-Positive Metastatic Breast Cancer Completed NCT00105456 Phase 4
31 Effects of Dexmedetomidine During Radiofrequency Ablation of Abdominal Tumours Completed NCT02016391 Phase 4 Dexmedetomidine
32 Accelerated Radiotherapy Outcomes in Women Completed NCT00156130 Phase 4
33 Rivaroxaban for the Prevention of Venous Thromboembolism in Asian Patients With Cancer Completed NCT01989845 Phase 4 Rivaroxaban
34 Taste, Smell and Chemotherapy (TASTY) Completed NCT01641172 Phase 4
35 Cardiac Valve Complications in Prolactinomas Treated With Cabergoline Completed NCT00460616 Phase 4 Cabergoline
36 The Effect of Perioperative Intravenous Magnesium on Pain After Endoscopic Submucosal Dissection for Gastric Neoplasm: Prospective Randomized Double-blind Placebo Controlled Study Completed NCT02235246 Phase 4 Magnesium Sulfate;Normal saline
37 A Study of Daclizumab (Zenapax) in Combination With Mycophenolate Mofetil (CellCept) and Sirolimus in Prevention of Acute Rejection in Heart Transplant Participants Completed NCT02554955 Phase 4 Daclizumab;Mycophenolate mofetil;Silrolimus
38 Radiation Exposure Reduction in Supraventricular Tachycardia Ablation Completed NCT01132274 Phase 4
39 Effects of Dexmedetomidine During IRE Procedures for Solid Tumours Completed NCT02044224 Phase 4 Dexmedetomidine
40 The Pharmacokinetics of 4% Lidocaine Gel When Applied Topically to the Breasts Completed NCT00925353 Phase 4 4% lidocaine gel
41 Protective Effect of EPA on Cardiovascular Events Completed NCT00231738 Phase 4 Eicosapentaenoic acid ethyl ester(EPADEL Capsule 300 TM)
42 Remifentanil Infusion Alone During the Closure Period for Early Emergence Following Craniotomy Completed NCT02593942 Phase 4 Remifentanil;Propofol
43 Effect of 5 Years of GH Replacement on Atherosclerosis Completed NCT00462475 Phase 4 Recombinant Growth Hormone, Genotropin (Pfizer)
44 Anti-fatigue Effect of Korean Red Ginseng in Patients With Non-alcoholic Hepatitis Completed NCT02331589 Phase 4 KRG (Korea Red ginseng);Placebo (for KRG)
45 Improvement of Fluid Balance in Patients Undergoing Surgery of the Colon and Rectum Completed NCT01175317 Phase 4
46 Safety and Efficacy of Intravenous Tranexamic Acid in Endoscopic Transurethral Resections in Urology Completed NCT02653261 Phase 4 Tranexamic Acid;Placebo
47 Deep Neuromuscular Relaxation in Patients for Thoraco-laparoscopic Esophagectomy Completed NCT02320734 Phase 4 Rocuronium
48 Fractionated Versus Target-controlled Propofol Administration in Bronchoscopy Completed NCT02246023 Phase 4
49 A Study to Evaluate the Efficacy and Safety of Zenapax in Combination With CellCept, Cyclosporine, and Corticosteroids in Patients Undergoing Cardiac Transplantation Completed NCT00048165 Phase 4 Daclizumab;Methylprednisolone;Mycophenolate mofetil;Placebo;cyclosporine
50 Non-small Cell Lung Cancer Registry Completed NCT00099541 Phase 4 zoledronic acid

Search NIH Clinical Center for Heart Tumor

Genetic Tests for Heart Tumor

Anatomical Context for Heart Tumor

MalaCards organs/tissues related to Heart Tumor:

39
Lung, Heart, Prostate, Bone, Kidney, Myeloid, T Cells

Publications for Heart Tumor

Articles related to Heart Tumor:

id Title Authors Year
1
A Giant Heart Tumor in Neonate with Clinical Signs of Pierre - Robin Syndrome. ( 28790548 )
2017
2
Heart palpitations as anA early presentation of aA heart tumor. ( 28009999 )
2016
3
ECG of the Month. Cardiac arrhythmia associated with atrial fibrosis and a heart tumor. ( 23902440 )
2013
4
Case report of death from falling: Did heart tumor cause syncope? ( 22081041 )
2012
5
Implantable cardioverter defibrillator in a 4-month-old infant with cardiac arrest associated with a vascular heart tumor. ( 11816644 )
2001
6
An uncommon heart tumor: the fibrosarcoma. ( 9251742 )
1997
7
Resection of a heart tumor using autotransplantation. ( 3287682 )
1988
8
Prenatal diagnosis of a heart tumor. ( 3400578 )
1988
9
Electrocardiographic diagnosis of a metastatic heart tumor. ( 1277832 )
1976
10
Primary malignant heart tumor diagnosed in vivo with the aid of artificial pneumopericardium. ( 18107158 )
1949

Variations for Heart Tumor

Expression for Heart Tumor

Search GEO for disease gene expression data for Heart Tumor.

Pathways for Heart Tumor

GO Terms for Heart Tumor

Biological processes related to Heart Tumor according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 animal organ morphogenesis GO:0009887 9.32 BCL2 PTCH1
2 positive regulation of endothelial cell proliferation GO:0001938 9.26 ANG CCL26
3 regulation of protein localization GO:0032880 9.16 BCL2 PTCH1
4 branching involved in ureteric bud morphogenesis GO:0001658 8.96 BCL2 PTCH1
5 ovarian follicle development GO:0001541 8.62 ANG BCL2

Molecular functions related to Heart Tumor according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 heparin binding GO:0008201 8.62 ANG PTCH1

Sources for Heart Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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