HCDD
MCID: HVY003
MIFTS: 21

Heavy Chain Deposition Disease (HCDD) malady

Nephrological diseases, Blood diseases, Cancer diseases, Rare diseases categories
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Summaries for Heavy Chain Deposition Disease

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33MalaCards
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MalaCards: Heavy Chain Deposition Disease, also known as HCDD, is related to light and heavy chain deposition disease and cutis laxa. Affiliated tissues include skeletal muscle, kidney and lung.

Aliases & Classifications for Heavy Chain Deposition Disease

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49Orphanet, 62UMLS, 59SNOMED-CT via Orphanet, 26ICD10 via Orphanet
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Related Diseases for Heavy Chain Deposition Disease

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17GeneCards, 18GeneDecks
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Diseases related to Heavy Chain Deposition Disease via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 14)
idRelated DiseaseScoreTop Affiliating Genes
1light and heavy chain deposition disease10.8
2cutis laxa10.4
3amyloidosis10.4
4light chain deposition disease10.4
5diabetic nephropathy10.2
6gamma heavy chain disease10.2
7proliferative glomerulonephritis10.2
8glomerulonephritis10.2
9glomerulosclerosis10.2
10lung cancer10.2
11multiple myeloma10.2
12myeloma10.2
13neuropathy10.2
14acquired cutis laxa10.2

Graphical network of diseases related to Heavy Chain Deposition Disease:



Diseases related to heavy chain deposition disease

Symptoms for Heavy Chain Deposition Disease

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Drugs & Therapeutics for Heavy Chain Deposition Disease

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Sources:
42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

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Search NIH Clinical Center for Heavy Chain Deposition Disease

Genetic Tests for Heavy Chain Deposition Disease

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Anatomical Context for Heavy Chain Deposition Disease

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33MalaCards
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MalaCards organs/tissues related to Heavy Chain Deposition Disease:

33
Skeletal muscle, Kidney, Lung, Skin

Animal Models for Heavy Chain Deposition Disease or affiliated genes

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Publications for Heavy Chain Deposition Disease

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52PubMed
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Articles related to Heavy Chain Deposition Disease:

(show all 34)
idTitleAuthorsYear
1
A case of renal I^2 heavy-chain deposition disease accompanied by rapid progressive renal failure. (23963539)
2013
2
Heavy chain deposition disease: an overview. (23652830)
2013
3
Long-term follow-up after autologous stem cell transplantation for light- and heavy-chain deposition disease. (22231462)
2012
4
High-dose melphalan followed by auto-SCT has favorable safety and efficacy in selected patients with light chain deposition disease and light and heavy chain deposition disease. (21499318)
2012
5
Renal crescentic alpha heavy chain deposition disease: a report of 3 cases and review of the literature. (21944962)
2011
6
Pulmonary light and heavy chain deposition disease: a pitfall for lung cancer evaluation with F-18 FDG PET/CT. (20631525)
2010
7
Intracellular extraocular muscle light- and heavy-chain deposition disease contributing to compressive optic neuropathy in a patient with preexisting Graves' orbitopathy. (19707026)
2010
8
Clinicopathological features and prognosis in immunoglobulin light and heavy chain deposition disease. (19203545)
2009
9
Acquired cutis laxa associated with heavy chain deposition disease. (19119136)
2008
10
Clinical remission and histopathological resolution of nodular lesions in a patient with gamma3 heavy-chain deposition disease. (18538103)
2008
11
A concurrence of light and heavy chain deposition disease and diabetic nephropathy. (18041443)
2007
12
Immunoglobulin light (heavy)-chain deposition disease: from molecular medicine to pathophysiology-driven therapy. (17699367)
2006
13
Recurrent light and heavy chain deposition disease after renal transplantation. (15840680)
2005
14
High dose chemotherapy and stem cell support in a patient of light- and heavy-chain deposition disease with abnormal marrow cell surface antigens and no monoclonal protein. (16258214)
2005
15
Light- and heavy-chain deposition disease (LHCDD): difficulty in diagnosis and treatment. (16258202)
2005
16
Development of systemic lambda-light chain amyloidosis in a patient with gamma-heavy chain deposition disease during long-term follow-up. (15673693)
2005
17
A case of monoclonal immunoglobulin light- and heavy-chain deposition disease exhibiting atypical deposition with fibrillary structures, successfully treated with chemotherapy. (16175947)
2005
18
Nodal marginal-zone lymphoma associated with monoclonal light-chain and heavy-chain deposition disease. (15172359)
2004
19
High dose chemotherapy in light chain or light and heavy chain deposition disease. (14717936)
2004
20
Intracapillary proliferative glomerulonephritis due to heavy chain deposition disease. (15102968)
2004
21
Articular, monoclonal gamma3 heavy-chain deposition disease: characterization of a partially deleted heavy-chain gene and its protein product synthesized in vivo and in vitro. (14613292)
2003
22
Generalized cutis laxa associated with heavy chain deposition disease. (14973644)
2003
23
Abnormal immunoglobulin synthesis in monoclonal immunoglobulin light chain and light and heavy chain deposition disease. (11409038)
2001
24
Heavy chain deposition disease: recurrence in a renal transplant and report of IgG(2) subtype. (10793054)
2000
25
The amino acid sequence of a monoclonal gamma 3-heavy chain from a patient with articular gamma-heavy chain deposition disease. (10849371)
2000
26
Heavy chain deposition disease: the disease spectrum. (10213655)
1999
27
Non-amyloid fibrils in heavy chain deposition disease. (10504516)
1999
28
IgG heavy-chain deposition disease affecting kidney, skin, and skeletal muscle. (9681738)
1998
29
Gamma-heavy chain deposition disease showing nodular glomerulosclerosis. (8719552)
1995
30
Light-heavy chain deposition disease progressing to multiple myeloma. (7485106)
1995
31
Structure of abnormal heavy chains in human heavy-chain-deposition disease. (7744049)
1995
32
IgG heavy-chain deposition disease. (7838842)
1994
33
Brief report: heavy-chain deposition disease. (8413435)
1993
34
Mechanisms of disease: monoclonal immunoglobulin deposition. Amyloidosis, light chain deposition disease, and light and heavy chain deposition disease. (1582976)
1992

Variations for Heavy Chain Deposition Disease

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Expression for genes affiliated with Heavy Chain Deposition Disease

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15Gene Expression Omnibus DataSets
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Search GEO for disease gene expression data for Heavy Chain Deposition Disease.

Pathways for genes affiliated with Heavy Chain Deposition Disease

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Compounds for genes affiliated with Heavy Chain Deposition Disease

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GO Terms for genes affiliated with Heavy Chain Deposition Disease

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Products for genes affiliated with Heavy Chain Deposition Disease

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Heavy Chain Deposition Disease

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet