HCDD
MCID: HVY003
MIFTS: 20

Heavy Chain Deposition Disease (HCDD) malady

Nephrological diseases, Blood diseases, Cancer diseases, Rare diseases categories
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Summaries for Heavy Chain Deposition Disease

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MalaCards based summary: Heavy Chain Deposition Disease, also known as HCDD, is related to light and heavy chain deposition disease and cutis laxa. Affiliated tissues include skeletal muscle, kidney and lung.

Aliases & Classifications for Heavy Chain Deposition Disease

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Sources:
48Orphanet, 62UMLS, 26ICD10 via Orphanet
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Related Diseases for Heavy Chain Deposition Disease

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Diseases related to Heavy Chain Deposition Disease via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 14)
idRelated DiseaseScoreTop Affiliating Genes
1light and heavy chain deposition disease10.8
2cutis laxa10.4
3amyloidosis10.4
4light chain deposition disease10.4
5diabetic nephropathy10.2
6glomerulonephritis10.2
7multiple myeloma10.2
8proliferative glomerulonephritis10.2
9gamma heavy chain disease10.2
10glomerulosclerosis10.2
11lung cancer10.2
12myeloma10.2
13neuropathy10.2
14acquired cutis laxa10.2

Graphical network of diseases related to Heavy Chain Deposition Disease:



Diseases related to heavy chain deposition disease

Symptoms for Heavy Chain Deposition Disease

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Drugs & Therapeutics for Heavy Chain Deposition Disease

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Drug clinical trials:

Search ClinicalTrials for Heavy Chain Deposition Disease

Search NIH Clinical Center for Heavy Chain Deposition Disease

Genetic Tests for Heavy Chain Deposition Disease

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Anatomical Context for Heavy Chain Deposition Disease

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MalaCards organs/tissues related to Heavy Chain Deposition Disease:

32
Skeletal muscle, Kidney, Lung, Skin

Animal Models for Heavy Chain Deposition Disease or affiliated genes

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Publications for Heavy Chain Deposition Disease

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Articles related to Heavy Chain Deposition Disease:

(show all 37)
idTitleAuthorsYear
1
Use of bortezomib in heavy-chain deposition disease: a report of 3 cases. (24613055)
2014
2
Acquired cutis laxa associated with heavy chain deposition disease involving dermal elastic fibers. (25133950)
2014
3
IgD Heavy-Chain Deposition Disease: Detection by Laser Microdissection and Mass Spectrometry. (25194005)
2014
4
A Unique Case of I^-heavy Chain Deposition Disease Characterized by Concomitant Deposition of I^2 and I^4 Subclasses. (25400185)
2014
5
A case of renal I^2 heavy-chain deposition disease accompanied by rapid progressive renal failure. (23963539)
2013
6
Heavy chain deposition disease: an overview. (23652830)
2013
7
Long-term follow-up after autologous stem cell transplantation for light- and heavy-chain deposition disease. (22231462)
2012
8
High-dose melphalan followed by auto-SCT has favorable safety and efficacy in selected patients with light chain deposition disease and light and heavy chain deposition disease. (21499318)
2012
9
Renal crescentic alpha heavy chain deposition disease: a report of 3 cases and review of the literature. (21944962)
2011
10
Pulmonary light and heavy chain deposition disease: a pitfall for lung cancer evaluation with F-18 FDG PET/CT. (20631525)
2010
11
Intracellular extraocular muscle light- and heavy-chain deposition disease contributing to compressive optic neuropathy in a patient with preexisting Graves' orbitopathy. (19707026)
2010
12
Clinicopathological features and prognosis in immunoglobulin light and heavy chain deposition disease. (19203545)
2009
13
Clinical remission and histopathological resolution of nodular lesions in a patient with gamma3 heavy-chain deposition disease. (18538103)
2008
14
A concurrence of light and heavy chain deposition disease and diabetic nephropathy. (18041443)
2007
15
Immunoglobulin light (heavy)-chain deposition disease: from molecular medicine to pathophysiology-driven therapy. (17699367)
2006
16
Recurrent light and heavy chain deposition disease after renal transplantation. (15840680)
2005
17
High dose chemotherapy and stem cell support in a patient of light- and heavy-chain deposition disease with abnormal marrow cell surface antigens and no monoclonal protein. (16258214)
2005
18
Light- and heavy-chain deposition disease (LHCDD): difficulty in diagnosis and treatment. (16258202)
2005
19
Development of systemic lambda-light chain amyloidosis in a patient with gamma-heavy chain deposition disease during long-term follow-up. (15673693)
2005
20
A case of monoclonal immunoglobulin light- and heavy-chain deposition disease exhibiting atypical deposition with fibrillary structures, successfully treated with chemotherapy. (16175947)
2005
21
Nodal marginal-zone lymphoma associated with monoclonal light-chain and heavy-chain deposition disease. (15172359)
2004
22
High dose chemotherapy in light chain or light and heavy chain deposition disease. (14717936)
2004
23
Intracapillary proliferative glomerulonephritis due to heavy chain deposition disease. (15102968)
2004
24
Articular, monoclonal gamma3 heavy-chain deposition disease: characterization of a partially deleted heavy-chain gene and its protein product synthesized in vivo and in vitro. (14613292)
2003
25
Generalized cutis laxa associated with heavy chain deposition disease. (14973644)
2003
26
Abnormal immunoglobulin synthesis in monoclonal immunoglobulin light chain and light and heavy chain deposition disease. (11409038)
2001
27
Heavy chain deposition disease: recurrence in a renal transplant and report of IgG(2) subtype. (10793054)
2000
28
The amino acid sequence of a monoclonal gamma 3-heavy chain from a patient with articular gamma-heavy chain deposition disease. (10849371)
2000
29
Heavy chain deposition disease: the disease spectrum. (10213655)
1999
30
Non-amyloid fibrils in heavy chain deposition disease. (10504516)
1999
31
IgG heavy-chain deposition disease affecting kidney, skin, and skeletal muscle. (9681738)
1998
32
Gamma-heavy chain deposition disease showing nodular glomerulosclerosis. (8719552)
1995
33
Light-heavy chain deposition disease progressing to multiple myeloma. (7485106)
1995
34
Structure of abnormal heavy chains in human heavy-chain-deposition disease. (7744049)
1995
35
IgG heavy-chain deposition disease. (7838842)
1994
36
Brief report: heavy-chain deposition disease. (8413435)
1993
37
Mechanisms of disease: monoclonal immunoglobulin deposition. Amyloidosis, light chain deposition disease, and light and heavy chain deposition disease. (1582976)
1992

Variations for Heavy Chain Deposition Disease

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Expression for genes affiliated with Heavy Chain Deposition Disease

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Search GEO for disease gene expression data for Heavy Chain Deposition Disease.

Pathways for genes affiliated with Heavy Chain Deposition Disease

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Compounds for genes affiliated with Heavy Chain Deposition Disease

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GO Terms for genes affiliated with Heavy Chain Deposition Disease

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Products for genes affiliated with Heavy Chain Deposition Disease

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  • Antibodies
  • Proteins
  • Lysates

Sources for Heavy Chain Deposition Disease

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet