MCID: HLM001
MIFTS: 42

Helminthiasis malady

Rare diseases, Infectious diseases, Gastrointestinal diseases categories
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Summaries for Helminthiasis

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65Wikipedia, 33MalaCards
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Wikipedia:65 Helminthiasis /?h?lmin??a??sis/ (alternatively spelled helminthosis; plural helminthiases) is any... more...

MalaCards: Helminthiasis, also known as intestinal helminthiasis, is related to schistosomiasis and filariasis. An important gene associated with Helminthiasis is RNASE3 (ribonuclease, RNase A family, 3), and among its related pathways are IL4-mediated signaling events and Glucocorticoid receptor regulatory network. The drugs niclosamide and antihelminthic [epc] and the compounds trimellitic anhydride and methyltetrahydrophthalic anhydride have been mentioned in the context of this disorder. Affiliated tissues include breast.

Aliases & Classifications for Helminthiasis

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43NIH Rare Diseases, 45Novoseek, 62UMLS, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Infectious diseases
Anatomical: Gastrointestinal diseases


Aliases & Descriptions:

helminthiasis 43 45 62
intestinal helminthiasis 43 62
worm infections 43


External Ids:

ICD1025 B83.9

Related Diseases for Helminthiasis

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17GeneCards, 18GeneDecks
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Diseases related to Helminthiasis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 112)
idRelated DiseaseScoreTop Affiliating Genes
1schistosomiasis30.9IL13, IL5, RNASE3, IGHE
2filariasis30.4IGHE, IL5, IL13
3toxocariasis30.1RNASE3, IGHE
4strongyloidiasis30.1IGHE, IL5
5eosinophilia30.1IL13, IL5, RNASE3, IGHE
6anisakiasis29.9IGHE, RNASE3
7asthma29.9IGHE, RNASE3, IL5, IL13
8atopic dermatitis29.9RNASE3, IL13
9paragonimiasis29.9IGHE, IL5
10onchocerciasis29.9RNASE3, IL5
11hypereosinophilic syndrome29.8IL5, RNASE3, IGHE
12dermatitis29.8IL13, IL5, IGHE
13atopy29.7IGHE, RNASE3, IL5, IL13
14malaria10.3
15giardiasis10.2
16intestinal schistosomiasis10.2
17ostertagiasis10.2
18ascariasis10.1
19bronchitis10.1RNASE3
20fasciolopsiasis10.1
21dracunculiasis10.1
22parasitic helminthiasis infectious disease10.1
23taeniasis10.1
24eosinophilic esophagitis10.1IL5
25conjunctivitis10.0IGHE, RNASE3
26dysentery10.0
27autosomal dominant hyper ige syndrome10.0IGHE, RNASE3
28bronchiectasis10.0IGHE, RNASE3
29otitis media10.0RNASE3, IGHE
30egg allergy10.0IGHE, IL5
31chronic eosinophilic pneumonia10.0RNASE3, IL5
32giant papillary conjunctivitis10.0RNASE3, IL5
33allergic bronchopulmonary aspergillosis10.0IGHE, IL5
34eosinophilic gastroenteritis10.0IGHE, IL5
35churg-strauss syndrome10.0RNASE3, IL5
36urticaria10.0RNASE3, IGHE
37contact dermatitis10.0IGHE, IL5
38pneumonia10.0IL13, IL5
39omenn syndrome10.0IL5, IGHE
40ulcerative colitis10.0IL13, RNASE3
41cutaneous leishmaniasis10.0IL5, IL13
42respiratory failure10.0IL13, RNASE3, IGHE
43esophagitis10.0IL5, IL13
44leishmaniasis10.0IL13, IL5
45intrinsic asthma10.0IGHE, RNASE3, IL5
46kimura disease10.0IGHE, RNASE3, IL5
47pulmonary disease, chronic obstructive10.0IL13, RNASE3
48angioedema10.0IL5, RNASE3, IGHE
49sinusitis10.0IGHE, RNASE3, IL5
50keratoconjunctivitis9.9IL13, IL5, RNASE3

Graphical network of the top 20 diseases related to Helminthiasis:



Diseases related to helminthiasis

Symptoms for Helminthiasis

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Drugs & Therapeutics for Helminthiasis

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Sources:
42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Drug clinical trials:

Search ClinicalTrials for Helminthiasis

Search NIH Clinical Center for Helminthiasis

Inferred drug relations via UMLS62/NDF-RT41:

Genetic Tests for Helminthiasis

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Anatomical Context for Helminthiasis

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33MalaCards
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MalaCards organs/tissues related to Helminthiasis:

33
Breast

Animal Models for Helminthiasis or affiliated genes

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Publications for Helminthiasis

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52PubMed
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Articles related to Helminthiasis:

(show top 50)    (show all 355)
idTitleAuthorsYear
1
Prevalence and risk factors associated with goat gastrointestinal helminthiasis in the SertALo region of ParaA-ba State, Brazil. (24214525)
2013
2
Repeated Schistosoma japonicum infection following treatment in two cohorts: evidence for host susceptibility to helminthiasis? (23505589)
2013
3
Control of soil-transmitted helminthiasis in Myanmar: results of 7A years of deworming. (23701018)
2013
4
Prevalence and intensity of intestinal helminthiasis in children living in orphanages in Benin City, Nigeria. (23362620)
2012
5
Mapping of schistosomiasis and soil-transmitted helminthiasis in the regions of centre, East and West Cameroon. (22413029)
2012
6
Improved mapping strategy to better inform policy on the control of schistosomiasis and soil-transmitted helminthiasis in Sierra Leone. (21645386)
2011
7
Cure rate is not a valid indicator for assessing drug efficacy and impact of preventive chemotherapy interventions against schistosomiasis and soil-transmitted helminthiasis. (21612808)
2011
8
Patterns and risk factors of helminthiasis and anemia in a rural and a peri-urban community in Zanzibar, in the context of helminth control programs. (20485491)
2010
9
Intestinal schistosomiasis and soil-transmitted helminthiasis in Ugandan schoolchildren: a rapid mapping assessment. (19908189)
2009
10
Can coverage of schistosomiasis and soil transmitted helminthiasis control programmes targeting school-aged children be improved? New approaches. (19178756)
2009
11
The plants, rituals and spells that 'cured' helminthiasis in Sicily. (18823529)
2008
12
Point prevalence of gastrointestinal helminthiasis in ruminants in southern Punjab, Pakistan. (17711599)
2007
13
Helminthiasis in selected children seen at the University of Benin Teaching Hospital (UBTH), Benin City, Nigeria. (15827592)
2005
14
Effectiveness of two annual, single-dose mass drug administrations of diethylcarbamazine alone or in combination with albendazole on soil-transmitted helminthiasis in filariasis elimination programme. (15361118)
2004
15
Use of benzimidazoles in children younger than 24 months for the treatment of soil-transmitted helminthiasis. (12745139)
2003
16
Concerns about recommending over-the-counter drugs to treat helminthiasis. (10367152)
1999
17
A school-based schistosomiasis and intestinal helminthiasis control programme in Nigeria: acceptability to community members. (9809919)
1998
18
Epidemiological study of intestinal helminthiasis in a Marrakech raw sewage spreading zone. (9531727)
1998
19
Intestinal helminthiasis, nutritional status, and their relationship; a cross-sectional study in urban slum school children in Indonesia. (9139384)
1995
20
Heligmosomoides polygyrus: a model for chronic gastrointestinal helminthiasis. (15463566)
1992
21
Urban helminthiasis in two socioeconomically distinct Costa Rican communities. (9709793)
1989
22
The treatment of intestinal helminthiasis with albendazole. (3569213)
1987
23
'Albendazole' in intestinal helminthiasis. (3093720)
1986
24
Helminthiasis and toxoplasmosis among exotic mammals at the Santiago National Zoo. (3505930)
1986
25
Albendazole in the treatment of intestinal helminthiasis in children. (3986860)
1985
26
Alternate grazing of horses and sheep as control for gastro-intestinal helminthiasis in horses. (6686382)
1983
27
A preliminary survey of malnutrition and helminthiasis among schoolchildren in one mountain and one lowland ujamaa village in Northern Tanzania. (7330928)
1981
28
Biliary lithiasis and helminthiasis. (7020457)
1981
29
Measuring malnutrition and intestinal helminthiasis on tobacco plantation workers' children. (503548)
1979
30
Chemotherapy of helminthiasis among wild mammals. IV. Efficacy of flubendazole 5% (R17889) against Trichuris trichiura infection of baboons, Papio hamadryas L. (754549)
1978
31
Haematological observations on the helminthiasis caused by Haemonchus contortus in Nigerian dwarf sheep. (906083)
1977
32
Mebendazole in the treatment of helminthiasis. (974969)
1976
33
IX. Helminthiasis. Trematode infections and cestode infections. (4614512)
1974
34
Helminthiasis in domestic and wild ruminants in Botswana-preliminary investigations. (4276422)
1972
35
Summary of recent abstracts. IX. Helminthiasis. Trematode infections. (4562258)
1972
36
Summary of recent abstracts. IX. Helminthiasis. Trematode infections. (4945419)
1971
37
Summary of recent abstracts. IX. Helminthiasis. Trematode infections and cestode infections. (4944786)
1971
38
Some aspects of naturally acquired helminthiasis of horses. (4120356)
1971
39
Helminthiasis. Nematode infections. (4925107)
1970
40
Helminthiasis. (4243492)
1969
41
Northern sylvatic helminthiasis. (5693140)
1968
42
Studies on the spring rise phenomenon in ovine helminthiasis. I. Spring rise in stabled sheep. (15846886)
1968
43
Intestinal helminthiasis in the rural area of Khuzestan, south-west Iran. (5582739)
1967
44
Human helminthiasis in America. (5864689)
1965
45
Helminthiasis of sheep in Southern Georgia. (13688538)
1961
46
Intestinal helminthiasis in six selected areas of Puerto Rico. (14420250)
1960
47
The use of dithiazanine in the treatment of helminthiasis in Mexican farm laborers. (13595202)
1958
48
Helminthiasis. (13455733)
1957
49
Incidence of intestinal helminthiasis in the Wu-Chia-Ling area and vicinity, Changsha, Hunan; with special reference to fasciolopsiasis buski. (14778142)
1950
50
Surgical aspects of helminthiasis. (15407897)
1949

Variations for Helminthiasis

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Expression for genes affiliated with Helminthiasis

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Helminthiasis

Search GEO for disease gene expression data for Helminthiasis.

Pathways for genes affiliated with Helminthiasis

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50PathCards, 38NCBI BioSystems Database, 61Tocris Bioscience, 30KEGG, 53QIAGEN, 54R&D Systems, 60Thomson Reuters
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Compounds for genes affiliated with Helminthiasis

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Sources:
45Novoseek, 61Tocris Bioscience, 29IUPHAR, 11DrugBank, 24HMDB, 51PharmGKB, 3BitterDB
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Compounds related to Helminthiasis according to GeneCards/GeneDecks:

(show top 50)    (show all 105)
idCompoundScoreTop Affiliating Genes
1trimellitic anhydride459.7IGHE, IL13
2methyltetrahydrophthalic anhydride459.7IL13, IGHE
3tele-methylhistamine459.5RNASE3, IGHE
4anti-histamine459.5RNASE3, IGHE
5mometasone furoate45 6110.4IL5, RNASE3
6oxatomide459.4IGHE, IL5
7levocabastine45 29 1111.4RNASE3, IL5
8desloratadine45 1110.2IL13, IGHE
9lte4459.1RNASE3, IL5
10unicap459.0IGHE, RNASE3, IL5
11beclomethasone dipropionate459.0IGHE, RNASE3, IL5
12formoterol45 29 1111.0IL13, RNASE3
13toluene diisocyanate459.0IGHE, RNASE3, IL5
14sodium cromoglycate459.0IGHE, RNASE3, IL5
15nedocromil sodium459.0IGHE, RNASE3, IL5
16cetirizine45 29 24 1112.0IGHE, RNASE3, IL5
17ketotifen45 1110.0IGHE, RNASE3, IL5
18azelastine45 1110.0IGHE, RNASE3, IL5
19capsaicin45 2910.0IL5, RNASE3, IGHE
20omalizumab45 119.9IGHE, IL5, IL13
21ovomucoid458.9IL13, IL5, IGHE
22salmeterol45 51 29 1111.9RNASE3, IL5, IL13
23penicillin458.9IL13, IL5, IGHE
24ltd4458.9IL13, IL5, RNASE3
25ltc4458.9IL13, IL5, RNASE3
26tarc458.9IL13, IL5, IGHE
27theophylline45 29 24 1111.8IL13, IL5, RNASE3
28leukotriene b445 61 2410.8RNASE3, IL5, IL13
29hydrocortisone45 3 61 1111.8IGHE, IL5, IL13
30thyroxine45 249.7IL13, IL5, IGHE
31isoproterenol45 119.7IGHE, IL5, IL13
32fmlp458.7RNASE3, IL5, IL13
33rantes458.5IL13, IL5, RNASE3
34praziquantel45 119.4IL13, IL5, RNASE3, IGHE
35montelukast45 51 29 1111.4IGHE, RNASE3, IL5, IL13
36budesonide45 51 1110.4IGHE, RNASE3, IL5, IL13
37salbutamol45 51 29 24 1112.4IGHE, RNASE3, IL5, IL13
38fluticasone propionate45 51 61 1111.4IGHE, RNASE3, IL5, IL13
39pgd2458.4IGHE, RNASE3, IL5, IL13
40methacholine45 51 1110.4IGHE, RNASE3, IL5, IL13
41allergens458.4IL13, IL5, RNASE3, IGHE
42prednisolone45 29 1110.4IGHE, RNASE3, IL5, IL13
43histamine45 29 2410.4IGHE, RNASE3, IL5, IL13
44cyclosporin a45 29 6110.4IGHE, RNASE3, IL5, IL13
45heparin45 29 24 1111.3IGHE, RNASE3, IL5, IL13
46adenylate458.3IGHE, RNASE3, IL5, IL13
47dexamethasone45 51 29 1111.3IL13, IL5, RNASE3, IGHE
48vegf458.3IGHE, RNASE3, IL5, IL13
49arginine458.3IL13, IL5, RNASE3, IGHE
50retinoic acid45 249.2IGHE, RNASE3, IL5, IL13

GO Terms for genes affiliated with Helminthiasis

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16Gene Ontology
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Cellular components related to Helminthiasis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055768.0IL13, IL5, RNASE3, IGHE

Biological processes related to Helminthiasis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of B cell proliferationGO:0308909.0IL13, IL5
2immune responseGO:0069558.2IL13, IL5, IGHE

Molecular functions related to Helminthiasis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cytokine activityGO:0051259.0IL13, IL5

Products for genes affiliated with Helminthiasis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Helminthiasis

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet