MCID: HLM001
MIFTS: 30

Helminthiasis malady

Infectious diseases, Gastrointestinal diseases categories

Summaries for Helminthiasis

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63Wikipedia, 32MalaCards
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Wikipedia:63 Helminthiasis /ˌhɛlminˈθaɪəsis/ (alternatively spelled helminthosis; plural helminthiases) is any... more...

MalaCards: Helminthiasis, also known as intestinal helminthiasis, is related to schistosomiasis and filariasis. An important gene associated with Helminthiasis is RNASE3 (ribonuclease, RNase A family, 3), and among its related pathways are IL4-mediated signaling events and Toll-like Receptor Pathway. The drugs niclosamide and antihelminthic [epc] and the compounds trimellitic anhydride and methyltetrahydrophthalic anhydride have been mentioned in the context of this disorder.

Aliases & Classifications for Helminthiasis

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42NIH Rare Diseases, 44Novoseek, 60UMLS, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases
Anatomical: Gastrointestinal diseases


Aliases & Descriptions:

helminthiasis 42 44 60
intestinal helminthiasis 42 60
worm infections 42


External Ids:

ICD1025 B83.9

Related Diseases for Helminthiasis

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17GeneCards, 18GeneDecks
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Diseases related to Helminthiasis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 120)
idRelated DiseaseScoreTop Affiliating Genes
1schistosomiasis30.9IGHE, RNASE3, IL13, IL5
2filariasis30.4IL5, IL13, IGHE
3eosinophilia30.1IGHE, RNASE3, IL13, IL5
4toxocariasis30.0IGHE, RNASE3
5strongyloidiasis30.0IGHE, IL5
6asthma29.9IL5, IL13, RNASE3, IGHE
7anisakiasis29.8RNASE3, IGHE
8atopic dermatitis29.7RNASE3, IL13
9onchocerciasis29.7IL5, RNASE3
10paragonimiasis29.7IGHE, IL5
11dermatitis29.7IGHE, IL13, IL5
12intestinal schistosomiasis10.2
13malaria10.2
14giardiasis10.2
15ostertagiasis10.2
16ascariasis10.1
17urinary schistosomiasis10.0
18intestinal impaction10.0
19fasciolopsiasis10.0
20dracunculiasis10.0
21intestinal disease10.0
22parasitic helminthiasis infectious disease10.0
23taeniasis10.0
24dysentery10.0
25cystic fibrosis10.0RNASE3
26common cold10.0RNASE3
27eosinophilic esophagitis10.0IL5
28sarcoidosis10.0IL13
29graves' disease10.0IL13
30mycosis fungoides10.0IL5
31pulmonary fibrosis10.0IL13
32otitis media10.0IGHE, RNASE3
33arthritis10.0IL13
34diphtheria10.0IL13
35conjunctivitis10.0RNASE3, IGHE
36urticaria10.0IGHE, RNASE3
37hyper ige syndrome10.0IGHE, RNASE3
38churg-strauss syndrome10.0IL5, RNASE3
39eosinophilic gastroenteritis10.0IL5, IGHE
40chronic eosinophilic pneumonia10.0RNASE3, IL5
41egg allergy10.0IGHE, IL5
42giant papillary conjunctivitis10.0RNASE3, IL5
43allergic bronchopulmonary aspergillosis10.0IL5, IGHE
44contact dermatitis10.0IL5, IGHE
45rheumatoid arthritis10.0IL13, RNASE3
46tetanus10.0IL13, IL5
47omenn syndrome10.0IL5, IGHE
48cutaneous leishmaniasis10.0IL13, IL5
49bronchiectasis10.0IGHE, RNASE3
50leishmaniasis10.0IL5, IL13

Graphical network of the top 20 diseases related to Helminthiasis:



Diseases related to helminthiasis

Clinical Features for Helminthiasis

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Drugs & Therapeutics for Helminthiasis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Helminthiasis

Drug clinical trials:

Search ClinicalTrials for Helminthiasis

Search NIH Clinical Center for Helminthiasis

Search CenterWatch for Helminthiasis

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Helminthiasis

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Anatomical Context for Helminthiasis

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Animal Models for Helminthiasis or affiliated genes

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Publications for Helminthiasis

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Genetic Variations for Helminthiasis

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Expression for genes affiliated with Helminthiasis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Helminthiasis

Search GEO for disease gene expression data for Helminthiasis.

Pathways for genes affiliated with Helminthiasis

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Sources:
37NCBI BioSystems Database, 59Tocris Bioscience, 51QIAGEN, 52R&D Systems, 29KEGG, 12EMD Millipore
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Compounds for genes affiliated with Helminthiasis

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Sources:
44Novoseek, 28IUPHAR, 11DrugBank, 24HMDB, 59Tocris Bioscience, 49PharmGKB, 2BitterDB
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Compounds related to Helminthiasis according to GeneCards/GeneDecks:

(show top 50)    (show all 89)
idCompoundScoreTop Affiliating Genes
1trimellitic anhydride449.7IGHE, IL13
2methyltetrahydrophthalic anhydride449.7IGHE, IL13
3heparin44 28 11 2412.7IL13, RNASE3
4tele-methylhistamine449.6IGHE, RNASE3
5anti-histamine449.6IGHE, RNASE3
6mometasone furoate44 5910.4RNASE3, IL5
7loratadine44 11 2411.4IGHE, RNASE3
8levocabastine44 28 1111.4IL5, RNASE3
9oxatomide449.4IL5, IGHE
10formoterol44 28 1111.3IL13, RNASE3
11desloratadine44 1110.2IGHE, IL13
12lte4449.2IL5, RNASE3
13unicap449.0IL5, RNASE3, IGHE
14beclomethasone dipropionate449.0IGHE, RNASE3, IL5
15toluene diisocyanate449.0IL5, RNASE3, IGHE
16sodium cromoglycate449.0IL5, RNASE3, IGHE
17cetirizine44 28 11 2412.0RNASE3, IGHE, IL5
18nedocromil sodium449.0IL5, RNASE3, IGHE
19ketotifen44 1110.0IL5, RNASE3, IGHE
20azelastine44 1110.0IL5, IGHE, RNASE3
21capsaicin44 2810.0IL5, RNASE3, IGHE
22omalizumab44 119.9IGHE, IL13, IL5
23ovomucoid448.9IGHE, IL13, IL5
24salmeterol44 49 28 1111.9RNASE3, IL13, IL5
25penicillin448.9IL5, IL13, IGHE
26ltd4448.9IL13, IL5, RNASE3
27ltc4448.9RNASE3, IL13, IL5
28tarc448.9IGHE, IL13, IL5
29theophylline44 28 11 2411.9IL5, IL13, RNASE3
30leukotriene b444 59 2410.8RNASE3, IL13, IL5
31hydrocortisone44 2 59 1111.8IL13, IL5, IGHE
32thyroxine44 249.7IL5, IL13, IGHE
33isoproterenol44 119.7IL5, IL13, IGHE
34fmlp448.6IL13, RNASE3, IL5
35praziquantel44 119.4IL5, IL13, RNASE3, IGHE
36montelukast44 49 28 1111.4RNASE3, IGHE, IL13, IL5
37budesonide44 49 1110.4IGHE, IL5, IL13, RNASE3
38salbutamol44 49 28 11 2412.4IL5, IGHE, RNASE3, IL13
39fluticasone propionate44 49 59 1111.4IL13, IL5, IGHE, RNASE3
40pgd2448.4IL5, RNASE3, IL13, IGHE
41methacholine44 119.4IL13, IL5, RNASE3, IGHE
42allergens448.4IL5, IGHE, RNASE3, IL13
43prednisolone44 28 1110.4IGHE, IL5, RNASE3, IL13
44histamine44 28 2410.4IL13, RNASE3, IGHE, IL5
45cyclosporin a44 28 5910.3IL5, IL13, IGHE, RNASE3
46adenylate448.3IL5, RNASE3, IGHE, IL13
47dexamethasone44 49 28 1111.3RNASE3, IL13, IL5, IGHE
48vegf448.2IL5, IGHE, RNASE3, IL13
49arginine448.2RNASE3, IL13, IGHE, IL5
50retinoic acid44 248.7IGHE, IL13, IL5, RNASE3

GO Terms for genes affiliated with Helminthiasis

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16Gene Ontology
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Cellular components related to Helminthiasis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055768.0IL5, IL13, RNASE3, IGHE

Biological processes related to Helminthiasis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of B cell proliferationGO:0308909.0IL5, IL13
2immune responseGO:0069558.2IL5, IL13, IGHE

Products for genes affiliated with Helminthiasis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Helminthiasis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet