MCID: HMN016
MIFTS: 40

Hemangioendothelioma malady

Category: Rare diseases

Aliases & Classifications for Hemangioendothelioma

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Aliases & Descriptions for Hemangioendothelioma:

Name: Hemangioendothelioma 46 48 66

Classifications:



Summaries for Hemangioendothelioma

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NIH Rare Diseases:46 The term hemangioendothelioma describes several types of vascular neosplasms and includes both non-cancerous (benign) and cancerous (malignant) growths. the term has also been applied to those that show "borderline" behavior, intermediate between entirely benign hemangiomas and highly malignant angiosarcomas. hemangioendotheliomas are caused by abnormal growth of blood vessel cells, although the exact underlying cause for the abnormal growth is unknown. they can also develop in an organ, such as the liver or lung. they usually grow slowly and can sometimes spread to other tissues in the body (metastasize). examples of types of hemangioendotheliomas include spindle cell hemangioma; papillary intralymphatic (dabska tumor); retiform; kaposiform; epithelioid; pseudomyogenic (epithelioid sarcoma-like hemangioendothelioma); and composite. treatment depends on the type of hemangioendothelioma present but typically includes surgical excision (removal). last updated: 7/10/2013

MalaCards based summary: Hemangioendothelioma is related to epithelioid hemangioendothelioma and kaposiform hemangioendothelioma. An important gene associated with Hemangioendothelioma is CAMTA1 (Calmodulin Binding Transcription Activator 1), and among its related pathways are Cell adhesion_Plasmin signaling and Id Signaling Pathway. Affiliated tissues include liver, lung and bone, and related mouse phenotypes are liver/biliary system and respiratory system.

Wikipedia:69 Hemangioendothelioma is used to describe a group of vascular neoplasms that may be considered benign as... more...

Related Diseases for Hemangioendothelioma

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Diseases related to Hemangioendothelioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 166)
idRelated DiseaseScoreTop Affiliating Genes
1epithelioid hemangioendothelioma12.3
2kaposiform hemangioendothelioma12.2
3retiform hemangioendothelioma12.1
4composite hemangioendothelioma12.1
5spindle cell hemangioma11.6
6hepatitis10.7
7sarcoma10.3
8spinal muscular atrophy-dandy-walker malformation-cataracts syndrome10.2PGF, VEGFA
9hemangioma10.2
10congenital ichthyosiform erythroderma10.2PGF, VEGFA
11histoplasmosis10.2PGF, VEGFA
12hereditary renal cell carcinoma10.2PGF, VEGFA
13epithelioid sarcoma10.2
14mediastinitis10.1
15angiosarcoma10.1
16lymphocytes absent10.1FLT4, PROX1
17hydromyelia10.1FLT4, VEGFA
183-methylglutaconic aciduria10.1PGF, VEGFA
19hyperlucent lung10.1FLT4, PROX1
20endotheliitis10.1
21orofaciodigital syndrome vii10.1FLT4, PROX1
22thyroiditis10.0
23preeclampsia/eclampsia 19.9PGF, VEGFA
24hypothyroidism9.9
25cervicitis9.9
26angioma, tufted9.9
27hemangioma-thrombocytopenia syndrome9.9
28bladder urachal carcinoma9.9KDR, VEGFA
29lymphangiomatosis9.9
30arthrogryposis, ectodermal dysplasia, cleft lip/palate, and developmental delay9.9KDR, VEGFA
31pleural tuberculosis9.9PGF, VEGFA
32acute bilateral depigmentation of the iris9.9KDR, VEGFA
33acute dacryocystitis9.8KDR, VEGFA
34gastric small cell carcinoma9.8KDR, VEGFA
35pericardial effusion9.8
36lymphangioma9.8
37cavernous hemangioma9.8
38aneurysm9.8
39perivascular epithelioid cell tumor9.8KDR, VEGFA
40lens disease9.8KDR, VEGFA
41epidural abscess9.8KDR, VEGFA
42hemangioma, capillary infantile9.8FLT4, KDR
43diabetes mellitus, insulin-dependent, 39.8KDR, VEGFA
44hyperinsulinism9.8KDR, VEGFA
45budd-chiari syndrome9.7
46crohn's disease9.7
47lymphedema9.7
48primary biliary cirrhosis9.7
49fibroma9.7
50hemangiopericytoma9.7

Graphical network of the top 20 diseases related to Hemangioendothelioma:



Diseases related to hemangioendothelioma

Symptoms for Hemangioendothelioma

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Drugs & Therapeutics for Hemangioendothelioma

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Drugs for Hemangioendothelioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
VincristinePhase 28882068-78-2, 57-22-75978
Synonyms:
22-Oxovincaleukoblastin
22-Oxovincaleukoblastine
28379-27-3
57-22-7
AC1L1LJC
C07204
C46H56N4O10
CCRIS 5763
CHEBI:28445
CID5978
D08679
DB00541
EINECS 200-318-1
HMS2090E19
HSDB 3199
Indole alkaloid
LCR
LS-228
Leurocristine
Lilly 37231 (1:1 sulfate salt)
Liposomal Vincristine
Marqibo
NCGC00163700-01
NCI-C04864
NCI60_026703
NSC-67574
Onco TCS
 
Oncovin
Oncovin (1:1 sulfate salt)
Oncovine
Tecnocris
Tecnocris (TN)
UNII-5J49Q6B70F
VCR
VIN
Vincaleukoblastine, 22-oxo- 22-Oxovincaleukoblastine
Vincasar
Vincasar (1:1 sulfate salt)
Vincasar PFS
Vincrex
Vincrex (1:1 sulfate salt)
Vincristin
Vincristina
Vincristina [DCIT]
Vincristine (INN)
Vincristine Sulfate
Vincristine Sulfate PFS
Vincristine [INN:BAN]
Vincristinum
Vincristinum [INN-Latin]
Vincrstine
Vincrystine
Vinkristin
Z-D-Val-Lys(Z)-OH
vincristine
2
GemcitabinePhase 2192895058-81-460750
Synonyms:
103882-84-4
122111-03-9
2',2'-DiF-dC
2',2'-Difluoro-2'-deoxycytidine
2',2'-Difluorodeoxycytidine
2'-Deoxy-.beta.-D-2',2'-difluorocytidine
2'-Deoxy-2',2'-difluorocytidine
4-Amino-1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
4-Amino-1-[3,3-difluoro-4-hydroxy-5-(hydroxymethyl) tetrahydrofuran-2-yl]-1H-pyrimidin-2-one
4-amino-1-((2R,4R,5R)-3,3-Difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)pyrimidin-2(1H)-one
95058-81-4
AB1004842
AC1L1TUQ
C07650
CCRIS 8984
CHEBI:175901
CHEMBL888
CID60750
Cytidine, 2'-deoxy-2',2'-difluoro-2'-Deoxy-.beta.-D-2',2'-difluorocytidine
D02368
DB00441
DDFC
DFDC
DFdC
DFdCyd
Folfugem
GEO
Gamcitabine
GemLip
Gemcel
 
Gemcin
Gemcitabin
Gemcitabina
Gemcitabina [INN-Spanish]
Gemcitabine
Gemcitabine (USAN/INN)
Gemcitabine HCl
Gemcitabine hydrochloride
Gemcitabine stereoisomer
Gemcitabinum
Gemcitabinum [INN-Latin]
Gemtro
Gemzar
Gemzar (hydrochloride)
HMS2089P10
HSDB 7567
Inno-D07001
LS-59139
LY 188011
LY-188011
LY188011
NCGC00168784-01
NChemBio.2007.10-comp25
NSC 613327
NSC613327
TL8005979
UNII-B76N6SBZ8R
ZINC18279854
Zefei
gemcitabine
nchembio.573-comp7
nchembio.90-comp2
3
tremelimumabPhase 283
Synonyms:
206
CP675
 
CP675206
Ticilimumab
tremelimumab
4
BenzocainePhase 217941994-09-7, 94-09-72337
Synonyms:
(p-(Ethoxycarbonyl)phenylamine
06952_FLUKA
112909_ALDRICH
112909_SIAL
1333-08-0
23239-88-5
23239-88-5 (hydrochloride)
4 Aminobenzoic Acid Ethyl Ester
4-(Ethoxycarbonyl)aniline
4-(Ethoxycarbonyl)phenylamine
4-14-00-01129 (Beilstein Handbook Reference)
4-Aminobenzoate
4-Aminobenzoic acid
4-Aminobenzoic acid ethyl ester
4-Aminobenzoic acid, ethyl ester
4-Carbethoxyaniline
4-amino-benzoic acid ethyl ester
4-aminobenzoic acid ethyl ester
71123-91-6
94-09-7
94-09-7 (Parent)
A0271
AB00051923
AC1L1DGC
AC1Q341A
AC1Q64JE
AE-562/40377256
AI3-02081
AKOS000119763
AR-1H9065
Acetate, Benzocaine
Aethoform
Aethylium paraminobenzoicum
Amben ethyl ester
Americaine
Anaesthan-syngala
Anaesthesin
Anaesthesinum
Anaesthin
Anestezin
Anestezin [Russian]
Anesthesin
Anesthesine
Anesthone
BB_SC-0019
BPBio1_001017
BRD-K75466013-001-05-2
BRN 0638434
BSPBio_000923
BSPBio_001908
Baby Anbesol
Bensokain
Benzoak
Benzocaina
Benzocaina [INN-Spanish]
Benzocaine
Benzocaine (USP/INN)
Benzocaine Acetate
Benzocaine Formate
Benzocaine Hydrobromide
Benzocaine Hydrochloride
Benzocaine Methanesulfonate
Benzocaine [INN:BAN]
Benzocainum
Benzocainum [INN-Latin]
Benzoic acid, 4-amino-, ethyl ester
Benzoic acid, 4-amino-, ethyl ester, hydrochloride
Benzoic acid, amino-, ethyl ester
Benzoic acid, p-amino-, ethyl ester
C07527
CAS-94-09-7
CHEBI:116735
CHEMBL278172
CID2337
Caswell No. 430A
Chloraseptic
D001566
D00552
DB01086
Dermoplast
Diet Ayds
DivK1c_000932
E1501_SIGMA
EINECS 202-303-5
EPA Pesticide Chemical Code 097001
ETHYL-P-AMINOBENZOATE
Ethoform
Ethoforme
Ethyl 4-aminobenzoate
Ethyl 4-aminobenzoate hydrochloride
Ethyl 4-aminobenzoic acid
Ethyl Aminobenzoate
Ethyl PABA
 
Ethyl aminobenzoate
Ethyl aminobenzoate (JP15)
Ethyl aminobenzoate (VAN)
Ethyl aminobenzoic acid
Ethyl p-Aminobenzoate
Ethyl p-Aminophenylcarboxylate
Ethyl p-aminobenzenecarboxylate
Ethyl p-aminobenzoate
Ethyl p-aminobenzoic acid
Ethyl p-aminophenylcarboxylate
Ethylester kyseliny p-aminobenzoove
Ethylester kyseliny p-aminobenzoove [Czech]
Ethylis aminobenzoas
Formate, Benzocaine
HMS1570O05
HMS1920G09
HMS2091M11
HMS502O14
HSDB 7225
Hurricaine
Hydrobromide, Benzocaine
Hydrochloride, Benzocaine
I05-0204
IDI1_000932
Identhesin
KBio1_000932
KBio2_000474
KBio2_003042
KBio2_005610
KBio3_001408
KBioGR_000658
KBioSS_000474
Keloform
LS-35847
MLS001331704
MLS002153970
Methanesulfonate, Benzocaine
MolPort-000-871-526
NCGC00016352-01
NCGC00094598-01
NCGC00094598-02
NINDS_000932
NSC 122792
NSC 41531
NSC41531
NSC4688
Norcain
Norcaine
Norcainum
Oprea1_750694
Oprea1_827402
Ora-jel
Orabase-B
Orthesin
Otocain
Outgro
Parathesin
Parathesin (TN)
Parathesine
Prestwick0_000712
Prestwick1_000712
Prestwick2_000712
Prestwick3_000712
Prestwick_991
SMR000059025
SPBio_000134
SPBio_002844
SPECTRUM1500139
STK043620
Slim Mint Gum
Solarcaine
Solu H
Spectrum2_000117
Spectrum3_000314
Spectrum4_000249
Spectrum5_000860
Spectrum_000074
Topcaine
UNII-U3RSY48JW5
WLN: ZR DVO2
ZINC12358719
benzocaine
ethylaminobenzoate-4
h-4-abz-oet
nchembio.182-comp4
p-(Ethoxycarbonyl)aniline
p-Aminobenzoate
p-Aminobenzoic acid
p-Aminobenzoic acid ethyl ester
p-Aminobenzoic acid, ethyl ester
p-Aminobenzoic ethyl ester
p-Carbethoxyaniline
p-Ethoxycarboxylic Aniline
p-Ethoxycarboxylic aniline
5
sirolimusPhase 2186353123-88-95284616, 6436030, 46835353
Synonyms:
(-)-Rapamycin
(-)-rapamycin
1fkb
1pbk
23,27-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine
23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine
23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29
3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
53123-88-9
A422989, NSC226080
AC-722
AC1L1JH9
AC1L7MJ9
AC1L9ZMV
AY 22989
AY-22989
AY22989
Ambotz53123-88-9
Antibiotic AY 22989
BIDD:PXR0165
Bio1_000293
Bio1_000782
Bio1_001271
Bio2_000375
Bio2_000855
BiomolKI2_000084
C07909
C51H79NO13
CBiol_002007
CCRIS 9024
CHEBI:100923
CHEBI:9168
CHEMBL413
CID10213190
CID10795871
CID11949238
CID11959112
CID313006
CID478951
CID5040
CID5284616
CID5358081
CID5374464
CID5460439
CID5497196
CID5924240
CID6436030
CID6610270
CID6610346
CID6711160
CID6713081
CID9833581
CID9854379
CID9854380
CID9962926
CID9962928
D00753
DB00877
DE-109
DivK1c_006936
 
FT-0082351
HMS2089A21
HSDB 7284
KBio1_001880
KBio2_000410
KBio2_002978
KBio2_005546
KBio3_000779
KBio3_000780
KBioGR_000410
KBioSS_000410
LCP-Siro
LMPK06000003
LS-143290
MLS000028373
MS-R001
MolMap_000043
MolPort-003-959-433
NCGC00021305-05
NCI60_001851
NCIMech_000355
NSC 226080
NSC226080
Perceiva
QTL1_000069
R0395_SIAL
R0395_SIGMA
RAP
RAPA
RPM
Rapammune
Rapamune
Rapamune (TN)
Rapamycin
Rapamycin (TN)
Rapamycin C-7, analog 4
Rapamycin Immunosuppressant Drug
Rapamycin from Streptomyces hygroscopicus
S1039_Selleck
SIIA 9268A
SILA 9268A
SILA9268A
SMP1_000255
SMR000058564
Sirolimus
Sirolimus (RAPAMUNE)
Sirolimus (USAN/INN)
Sirolimus [USAN:BAN:INN]
Sirolimus, Rapamune,Rapamycin
SpecPlus_000840
UNII-W36ZG6FT64
UNM-0000358684
WY-090217
Wy 090217
heptadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy
nchembio.100-comp4
nchembio.2007.42-comp2
nchembio.79-comp1
nchembio762-comp1
nchembio883-comp3
rapamycin
sirolimus
6
EverolimusPhase 21863159351-69-66442177
Synonyms:
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.04,9)hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,23S,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriacont
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34as)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethy
07741_FLUKA
159351-69-6
40-O-(2-hydroxyethyl)-rapamycin
42-O-(2-Hydroxyethyl)rapamycin
Afinitor
CERTICAN(R)
CHEMBL1201755
Certican
D02714
DB01590
 
Everolimus
Everolimus (JAN/USAN/INN)
Everolimus [USAN]
LS-143292
MolPort-003-847-342
MolPort-003-925-588
NCGC00167512-01
NVP-RAD-001
RAD 001
RAD-001
RAD-001C
RAD001
RAD001, SDZ-RAD, Certican, Zortress, Afinitor, Everolimus
S1120_Selleck
SDZ-RAD
UNII-9HW64Q8G6G
Zortress
everolimus
7
MiconazolePhase 2357322916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
8
BevacizumabPhase 21938216974-75-3
Synonyms:
216974-75-3
Avastin
Avastin (TN)
Bevacizumab
Bevacizumab (genetical recombination)
 
Bevacizumab (genetical recombination) (JAN)
D06409
R-435
anti-VEGF monoclonal antibody
antiVEGF
bevacizumab
9tannic acidNutraceuticalPhase 21794
10
Ethiodized oil878008-53-5
Synonyms:
 
EOE 13

Interventional clinical trials:

idNameStatusNCT IDPhase
1Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic SarcomaCompletedNCT01154452Phase 1, Phase 2
2A Study to Compare Vincristine to Sirolimus for Treatment of High Risk Vascular TumorsRecruitingNCT02110069Phase 2
3Gemcitabine Hydrochloride With or Without Pazopanib Hydrochloride in Treating Patients With Refractory Soft Tissue SarcomaRecruitingNCT01532687Phase 2
4Multi-Arm Study to Test the Efficacy of Immunotherapeutic Agents in Multiple Sarcoma SubtypesRecruitingNCT02815995Phase 2
5Safety and Efficacy Study of Sirolimus in Complicated Vascular AnomaliesActive, not recruitingNCT00975819Phase 2
6Bevacizumab in Treating Patients With AngiosarcomaActive, not recruitingNCT00288015Phase 2
7Lymphatic Anomalies RegistryRecruitingNCT02399527
8Safety and Efficacy of Lipiodol® Ultra Fluid in Association With Surgical Glues During Vascular EmbolizationNot yet recruitingNCT02625389

Search NIH Clinical Center for Hemangioendothelioma

Genetic Tests for Hemangioendothelioma

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Anatomical Context for Hemangioendothelioma

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MalaCards organs/tissues related to Hemangioendothelioma:

34
Liver, Lung, Bone, Endothelial, Skin, Lymph node, Heart

Animal Models for Hemangioendothelioma or affiliated genes

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MGI Mouse Phenotypes related to Hemangioendothelioma:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.4FLT4, KDR, PROX1, VEGFA
2MP:00053888.4KDR, PGF, PROX1, VEGFA
3MP:00053917.9KDR, PGF, PROX1, VEGFA
4MP:00053877.8FLT4, KDR, PGF, PROX1, VEGFA
5MP:00028737.6CAMTA1, FLT4, KDR, PROX1, VEGFA
6MP:00053857.4FLT4, KDR, PGF, PROX1, VEGFA
7MP:00053787.1CAMTA1, FLT4, KDR, PGF, PROX1, VEGFA

Publications for Hemangioendothelioma

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Articles related to Hemangioendothelioma:

(show top 50)    (show all 872)
idTitleAuthorsYear
1
Epithelioid Hemangioendothelioma: a Rare Primary Thyroid Tumor with Confirmation of WWTR1 and CAMTA1 Rearrangements. (27026033)
2016
2
Recurrence of Epithelioid Hemangioendothelioma during Pregnancy: Case Report and Systematic Review. (27479949)
2016
3
Diagnostic utility of FOSB immunohistochemistry in pseudomyogenic hemangioendothelioma and its histological mimics. (27515856)
2016
4
Primary epithelioid hemangioendothelioma of the bladder: case report and review of the literature. (25502937)
2015
5
Spindle Cell Hemangioendothelioma: Rare Clinical Entity. (26538705)
2015
6
Resection of a right atrial epithelioid hemangioendothelioma. (26300384)
2015
7
Composite Hemangioendothelioma of the Submandibular Region. (25666464)
2015
8
Case of high-risk epithelioid hemangioendothelioma of the neck. (23019156)
2013
9
Recurrent hepatic epithelioid hemangioendothelioma after orthotopic liver transplantation. (24122824)
2013
10
A rare case of primary nodal hemangioendothelioma. (24260072)
2013
11
Hepatic epithelioid hemangioendothelioma treated with irreversible electroporation and antibiotics. (23897957)
2013
12
Management of synchronous vascular and ductal anomalies in living donor liver transplantation for hepatic epithelioid hemangioendothelioma. (24166881)
2013
13
Mediastinal epithelioid hemangioendothelioma with abundant spindle cells and osteoclast-like giant cells mimicking malignant fibrous histiocytoma. (23800015)
2013
14
Spindle-cell hemangioma (spindle-cell hemangioendothelioma): a diagnosis on fine-needle aspiration cytology. (22927295)
2012
15
Mediastinal epithelioid hemangioendothelioma mimicking a teratoma. (21492982)
2011
16
Spindle cell hemangioendothelioma of the temporal muscle resected with zygomatic osteotomy: a case report of an unusual intramuscular lesion mimicking sarcoma. (22606579)
2011
17
Translocation t(7;19)(q22;q13)a89a recurrent chromosome aberration in pseudomyogenic hemangioendothelioma? (21536240)
2011
18
Elevated serum I+-fetoprotein in a neonate with cutaneous infantile hemangioendothelioma. (21501314)
2011
19
Capillary-lymphatic malformation, kaposiform hemangioendothelioma and delayed Kasabach-Merritt phenomenon. (20403115)
2011
20
Epithelioid hemangioendothelioma of nasal cavity. (21346909)
2010
21
Lenalidomide stops progression of multifocal epithelioid hemangioendothelioma including intracranial disease. (19898746)
2010
22
Expression of prox1, lymphatic endothelial nuclear transcription factor, in Kaposiform hemangioendothelioma and tufted angioma. (20975337)
2010
23
Treatment of childhood kaposiform hemangioendothelioma with sirolimus. (20730884)
2010
24
A case of pulmonary epithelioid hemangioendothelioma. (20587617)
2010
25
Vincristine and corticosteroids as first-line treatment of Kasabach-Merritt syndrome in kaposiform hemangioendothelioma. (19426625)
2009
26
Hepatic epithelioid hemangioendothelioma (HEH) at MRI using reticuloendothelial system (RES)-specific contrast agent: the "bright-bright sign" rather than the "bright-dark sign". (19306449)
2009
27
Composite hemangioendothelioma of the oral cavity: case report and review of the literature. (18286494)
2008
28
Recurrent pedal hobnail (Dabska-retiform) hemangioendothelioma with forefoot reconstructive surgery using a digital fillet flap. (18725133)
2008
29
Epithelioid hemangioendothelioma of the oral cavity: a case report. (18587215)
2008
30
Pulmonary epithelioid hemangioendothelioma: report of three cases. (18751952)
2008
31
Pulmonary metastasis from hepatic epithelioid hemangioendothelioma; report of a case]. (17564071)
2007
32
Spindle cell hemangioma and epithelioid hemangioendothelioma arising in an area of lymphedema. (16778491)
2006
33
Epithelioid hemangioendothelioma of the submandibular triangle. (16929998)
2006
34
Case 96: Hepatic epithelioid hemangioendothelioma. (16793987)
2006
35
Right upper quadrant pain and fever in a 41-year-old man. Epithelioid hemangioendothelioma of the liver with metastasis to porta hepatis lymph nodes and lung. (15859662)
2005
36
Successful treatment of osteolytic epithelioid hemangioendothelioma with pamidronate. (15971432)
2005
37
A key angiogenic role of monocyte chemoattractant protein-1 in hemangioendothelioma proliferation. (15163622)
2004
38
Pathology quiz case 2. Diagnosis: Kaposiform hemangioendothelioma (KHE). (15313873)
2004
39
Infantile hemangioendothelioma. (14615570)
2003
40
Epithelioid hemangioendothelioma of the liver--characteristics on magnetic resonance imaging: case report. (10659062)
1999
41
Epithelioid hemangioendothelioma of the larynx. (10774577)
1999
42
Kaposiform hemangioendothelioma: a locally aggressive vascular tumor. (9591789)
1998
43
Successful multimodal therapy for kaposiform hemangioendothelioma complicated by Kasabach-Merritt phenomenon: case report and review of the literature. (9658430)
1998
44
Epithelioid hemangioendothelioma of soft tissue: report of a case with ultrastructural observations. (9491218)
1998
45
Cytologic evaluation of primary malignant vascular tumors of the liver. One case each of angiosarcoma and epithelioid hemangioendothelioma. (9305386)
1997
46
Epithelioid hemangioendothelioma of the lung. (8837341)
1996
47
CT of pulmonary epithelioid hemangioendothelioma. (8040439)
1994
48
Mediastinal epithelioid hemangioendothelioma. (2181956)
1990
49
Malignant epithelioid hemangioendothelioma at the site of a hip prosthesis. (3381668)
1988
50
Intravascular bronchioloalveolar tumor as a secondary manifestation of an epithelioid hemangioendothelioma. (3818539)
1986

Variations for Hemangioendothelioma

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Expression for genes affiliated with Hemangioendothelioma

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Search GEO for disease gene expression data for Hemangioendothelioma.

Pathways for genes affiliated with Hemangioendothelioma

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Pathways related to Hemangioendothelioma according to GeneCards Suite gene sharing:

(show all 22)
idSuper pathwaysScoreTop Affiliating Genes
19.1KDR, VEGFA
29.1KDR, VEGFA
39.1KDR, VEGFA
4
Show member pathways
9.1KDR, VEGFA
59.1KDR, VEGFA
6
Show member pathways
9.0FLT4, KDR
78.6KDR, PROX1, VEGFA
8
Show member pathways
8.6FLT4, KDR, PGF
9
Show member pathways
8.6FLT4, KDR, PGF
10
Show member pathways
8.5FLT4, KDR, PROX1
118.5FLT4, KDR, VEGFA
128.5FLT4, KDR, VEGFA
13
Show member pathways
8.1FLT4, KDR, PGF, VEGFA
14
Show member pathways
8.1FLT4, KDR, PGF, VEGFA
15
Show member pathways
8.1FLT4, KDR, PGF, VEGFA
16
Show member pathways
8.1FLT4, KDR, PGF, VEGFA
17
Show member pathways
8.1FLT4, KDR, PGF, VEGFA
18
Show member pathways
8.1FLT4, KDR, PGF, VEGFA
198.1FLT4, KDR, PGF, VEGFA
20
Show member pathways
8.1FLT4, KDR, PGF, VEGFA
21
Show member pathways
8.1FLT4, KDR, PGF, VEGFA
22
Show member pathways
8.1FLT4, KDR, PGF, VEGFA

GO Terms for genes affiliated with Hemangioendothelioma

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Biological processes related to Hemangioendothelioma according to GeneCards Suite gene sharing:

(show all 20)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of cell divisionGO:005178110.0PGF, VEGFA
2lymph vessel developmentGO:000194510.0FLT4, PROX1
3sprouting angiogenesisGO:000204010.0FLT4, PGF
4lymphangiogenesisGO:00019469.9FLT4, PROX1
5positive regulation of protein kinase C signalingGO:00900379.9FLT4, VEGFA
6positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathwayGO:00380339.8KDR, VEGFA
7cell migration involved in sprouting angiogenesisGO:00020429.8KDR, VEGFA
8positive regulation of positive chemotaxisGO:00509279.7KDR, VEGFA
9positive regulation of focal adhesion assemblyGO:00518949.7KDR, VEGFA
10vasculogenesisGO:00015709.6KDR, VEGFA
11positive regulation of MAPK cascadeGO:00434109.2FLT4, KDR
12positive regulation of angiogenesisGO:00457669.0KDR, PGF, VEGFA
13transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071698.9FLT4, KDR
14positive regulation of protein phosphorylationGO:00019348.9FLT4, KDR, VEGFA
15cellular response to vascular endothelial growth factor stimulusGO:00359248.8FLT4, KDR, VEGFA
16positive regulation of endothelial cell migrationGO:00105958.6FLT4, KDR, PROX1, VEGFA
17negative regulation of apoptotic processGO:00430668.6FLT4, KDR, VEGFA
18positive regulation of endothelial cell proliferationGO:00019388.0FLT4, KDR, PGF, PROX1, VEGFA
19vascular endothelial growth factor receptor signaling pathwayGO:00480107.8FLT4, KDR, PGF, VEGFA
20positive regulation of cell proliferationGO:00082847.5FLT4, KDR, PGF, PROX1, VEGFA

Molecular functions related to Hemangioendothelioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1vascular endothelial growth factor-activated receptor activityGO:00050219.3FLT4, KDR
2transmembrane receptor protein tyrosine kinase activityGO:00047149.0FLT4, KDR
3growth factor bindingGO:00198388.9FLT4, KDR

Sources for Hemangioendothelioma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet