MCID: HMN010
MIFTS: 59

Hemangioma

Categories: Cancer diseases, Genetic diseases

Aliases & Classifications for Hemangioma

Summaries for Hemangioma

Disease Ontology : 12 A cell type benign neoplasm that has physical basis in endothelial cells that line blood vessels and is characterised by increased number of normal or abnormal vessels filled with blood.

MalaCards based summary : Hemangioma is related to hemangioma, capillary infantile and hypoplastic left heart syndrome. An important gene associated with Hemangioma is KDR (Kinase Insert Domain Receptor), and among its related pathways/superpathways are PAK Pathway and Pathways in cancer. The drugs Sufentanil and Parecoxib have been mentioned in the context of this disorder. Affiliated tissues include Heart, liver and endothelial, and related phenotypes are cardiovascular system and cellular

Wikipedia : 72 A hemangioma, also known as infantile hemangioma (IH), is one of the most common benign tumors of... more...

Related Diseases for Hemangioma

Diseases in the Hemangioma family:

Malignant Hemangioma Acquired Hemangioma
Hemangioma, Hereditary Familial Hemangioma

Diseases related to Hemangioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 477)
id Related Disease Score Top Affiliating Genes
1 hemangioma, capillary infantile 34.3 ANTXR1 FLT4 KDR
2 hypoplastic left heart syndrome 29.8 KRIT1 TEK
3 hemopneumothorax 28.7 CD34 KRIT1
4 lung cancer 27.6 CYCS FGF2 FLT4 KDR KRAS NKX2-1
5 hematopoietic stem cell transplantation 20.7 ACTC1 ANGPT2 ANTXR1 CD34 CYCS DIO3
6 capillary hemangioma 12.2
7 cavernous hemangioma 12.2
8 hemangioma-thrombocytopenia syndrome 12.1
9 non-involuting congenital hemangioma 12.1
10 rapidly involuting congenital hemangioma 12.0
11 sclerosing hemangioma 12.0
12 glomeruloid hemangioma 12.0
13 intramuscular hemangioma 11.8
14 pulmonary sclerosing hemangioma 11.8
15 spindle cell hemangioma 11.8
16 histiocytoid hemangioma 11.8
17 skin hemangioma 11.8
18 giant hemangioma 11.8
19 hemangioma of liver 11.8
20 hemangioma of lung 11.8
21 supraumbilical midabdominal raphe and facial cavernous hemangiomas 11.8
22 hemangioma of spleen 11.8
23 venous hemangioma 11.8
24 hobnail hemangioma 11.8
25 breast hemangioma 11.8
26 gastric hemangioma 11.8
27 acquired hemangioma 11.8
28 bone epithelioid hemangioma 11.7
29 verrucous hemangioma 11.7
30 diffuse cavernous hemangioma of the rectum 11.7
31 malignant hemangioma 11.7
32 hemangioma, hereditary 11.7
33 hemangioma of orbit 11.7
34 cavernous hemangioma of orbit 11.7
35 intracranial structure hemangioma 11.7
36 hemangioma of intra-abdominal structure 11.7
37 central nervous system hemangioma 11.7
38 hemangioma of subcutaneous tissue 11.6
39 cavernous hemangioma of colon 11.6
40 hemangioma, capillary infantile susceptibility 11.6
41 breast epithelioid hemangioma 11.6
42 hemangiomas, cavernous, of face and supraumbilical midline raphe 11.6
43 skin epithelioid hemangioma 11.6
44 pyogenic granuloma 11.6
45 sacral hemangiomas multiple congenital abnormalities 11.6
46 verrucous keratotic hemangioma 11.6
47 cavernous hemangioma of face 11.6
48 familial hemangioma 11.6
49 partially involuting congenital hemangioma 11.6
50 transverse limb deficiency hemangioma 11.6

Graphical network of the top 20 diseases related to Hemangioma:



Diseases related to Hemangioma

Symptoms & Phenotypes for Hemangioma

MGI Mouse Phenotypes related to Hemangioma:

44 (show all 17)
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.47 ACTC1 ANGPT2 ANTXR1 CYCS FGF2 FLT4
2 cellular MP:0005384 10.43 PECAM1 PROX1 SLC2A1 VEGFA ACTC1 ANGPT2
3 homeostasis/metabolism MP:0005376 10.4 SLC2A1 TEK VEGFA ACTC1 ANGPT2 CD34
4 growth/size/body region MP:0005378 10.37 ACTC1 ANTXR1 CYCS DIO3 FLT4 KDR
5 mortality/aging MP:0010768 10.33 ACTC1 ANGPT2 ANTXR1 CYCS DIO3 FGF2
6 immune system MP:0005387 10.26 CD34 CYCS FLT4 KDR KRAS LYVE1
7 hematopoietic system MP:0005397 10.25 KRAS LYVE1 PDPN PECAM1 PROX1 TEK
8 digestive/alimentary MP:0005381 10.15 ANGPT2 FLT4 KRAS NKX2-1 PDPN PECAM1
9 embryo MP:0005380 10.14 CYCS FLT4 KDR KRAS KRIT1 SLC2A1
10 muscle MP:0005369 10.07 TEK VEGFA ACTC1 FGF2 FLT4 KDR
11 integument MP:0010771 10.06 ANGPT2 CD34 FLT4 KDR KRAS KRIT1
12 liver/biliary system MP:0005370 9.98 PECAM1 PROX1 VEGFA DIO3 FLT4 KDR
13 neoplasm MP:0002006 9.87 ANTXR1 CD34 FGF2 KRAS KRIT1 NKX2-1
14 respiratory system MP:0005388 9.81 ANGPT2 KDR KRAS NKX2-1 PDPN PECAM1
15 no phenotypic analysis MP:0003012 9.8 ANTXR1 FLT4 KDR KRAS NKX2-1 SLC2A1
16 skeleton MP:0005390 9.61 ANTXR1 CYCS FGF2 KDR KRAS NKX2-1
17 vision/eye MP:0005391 9.23 ANGPT2 FGF2 KDR KRAS KRIT1 PROX1

Drugs & Therapeutics for Hemangioma

Drugs for Hemangioma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 199)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Sufentanil Approved, Investigational Phase 4 56030-54-7 41693
2 Parecoxib Approved Phase 4 198470-84-7
3
Propranolol Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 525-66-6 4946
4
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-24-8 5755
5
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 83-43-2 6741
6
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 68602 5311068 56032
7
Ethiodized oil Approved Phase 4 8008-53-5
8 Analgesics Phase 4
9 Central Nervous System Depressants Phase 4
10 Adjuvants, Anesthesia Phase 4
11 Adrenergic Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
12 Adrenergic Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
13 Adrenergic beta-Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
14 Narcotics Phase 4
15 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
16 Cyclooxygenase 2 Inhibitors Phase 4
17 Cyclooxygenase Inhibitors Phase 4
18 Analgesics, Non-Narcotic Phase 4
19 Analgesics, Opioid Phase 4
20 Anesthetics Phase 4
21 Anesthetics, General Phase 4
22 Anesthetics, Intravenous Phase 4
23 Anti-Arrhythmia Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
24 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
25 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2
26 Anti-Inflammatory Agents, Non-Steroidal Phase 4
27 Antihypertensive Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
28 Autonomic Agents Phase 4,Phase 3,Phase 2
29 Antirheumatic Agents Phase 4
30 Prednisolone acetate Phase 4,Phase 3,Phase 2
31 glucocorticoids Phase 4,Phase 3,Phase 2
32 Methylprednisolone acetate Phase 4,Phase 3,Phase 2
33 Methylprednisolone Hemisuccinate Phase 4,Phase 3,Phase 2
34 Adrenergic Agonists Phase 4
35 Adrenergic alpha-Agonists Phase 4
36 Gastrointestinal Agents Phase 4,Phase 3,Phase 2
37 Neuroprotective Agents Phase 4,Phase 3,Phase 2
38 Hormone Antagonists Phase 4,Phase 3,Phase 2
39 Hormones Phase 4,Phase 3,Phase 2
40 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2
41 Vasodilator Agents Phase 4,Phase 2,Phase 3,Phase 1
42 Prednisolone hemisuccinate Phase 4,Phase 3,Phase 2
43 Prednisolone phosphate Phase 4,Phase 3,Phase 2
44 Antiemetics Phase 4,Phase 3,Phase 2
45 Protective Agents Phase 4,Phase 3,Phase 2
46 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2
47 Adrenergic alpha-2 Receptor Agonists Phase 4
48 Hypnotics and Sedatives Phase 4
49
Timolol Approved Phase 3,Phase 2,Phase 1,Early Phase 1 26839-75-8 33624 5478
50
Ephedrine Approved Phase 3 299-42-3 9294

Interventional clinical trials:

(show top 50) (show all 191)

id Name Status NCT ID Phase Drugs
1 Role of Parecoxib Sodium for Postoperative Pain Management in Open Hepatectomy Unknown status NCT02204878 Phase 4 Parecoxib Sodium
2 The Safety and Efficiency of Propranolol as an Initial Treatment for Pediatric Hemangioma Completed NCT01908972 Phase 4 Prednisolone;Propranolol
3 Postmarketing Safety Study of Hemoporfin in Patients With Port Wine Stain Recruiting NCT03181984 Phase 4 Hemoporfin
4 A Pilot Study of Hemoporfin PDT in Children With Port-wine Stain Recruiting NCT03125057 Phase 4 Hemoporfin PDT
5 Effect of Dexmedetomidine Combined With Sufentanil for Postoperative Intravenous Analgesia in Neurosurgery Recruiting NCT02552459 Phase 4 Sufentanil;dexmedetomidine 1;dexmedetomidine 2;dexmedetomidine 3
6 Apollo™ Onyx™ Delivery Micro Catheter Post Market Safety Study Active, not recruiting NCT02378883 Phase 4
7 Evaluation of Lipiodol® Ultra Fluid in Association With Surgical Glues During Vascular Embolization. Not yet recruiting NCT02625389 Phase 4 Lipiodol® Ultra Fluid with surgical glues
8 Visceral Artery Aneurysm Embolization by the Penumbra Ruby™ Coil System Not yet recruiting NCT02079818 Phase 4
9 Topical Timolol for Superficial Infantile Hemangioma Unknown status NCT01685398 Phase 3 0.5% timolol maleate eye drop;Normal saline
10 Treatment of Port Wine Stains in Children With Pulsed Dye Laser and Timolol Gel Unknown status NCT01272609 Phase 3 Timolol + LCP
11 Functional Magnetic Resonance Imagine(fMRI)Navigation in Intracranial Arteriovenous Malformation Surgery Unknown status NCT01758211 Phase 3
12 Study to Demonstrate the Efficacy and Safety of Propranolol Oral Solution in Infants With Proliferating Infantile Hemangiomas Requiring Systemic Therapy Completed NCT01056341 Phase 2, Phase 3 Propranolol;Placebo
13 Pulse Steroids Versus Oral Steroids in Problematic Hemangiomas of Infancy Completed NCT00312520 Phase 3 prednisolone;methylprednisolone
14 Evaluation of Vertebroplasty Associated With Radiotherapy for Spine Metastases (EVAR) Completed NCT00267033 Phase 3
15 A Multicenter, Open-label Study for E7040 in Japanese Subjects With Hypervascular Tumor and Subjects With Arteriovenous Malformation Completed NCT01677624 Phase 3
16 A Randomized Trial of Unruptured Brain AVMs Completed NCT00389181 Phase 3
17 Nadolol Versus Propranolol in Children With Infantile Hemangiomas Recruiting NCT02505971 Phase 3 Nadolol;Propranolol
18 CyberKnife Based Hypofractionated Radiotherapy for Vertebral Hemangiomas Recruiting NCT02332408 Phase 3
19 Comparative Study to Evaluate the Effectiveness of Atenolol and Propranolol in the Treatment of Infantile Hemangiomas Recruiting NCT03237637 Phase 3 oral propranolol;oral atenolol
20 Efficacy and Safety of Propranolol Versus Atenolol on the Proliferative Phase of Infantile Hemangioma Recruiting NCT02342275 Phase 3 Propranolol;Atenolol
21 Trial of Sirolimus for Cognitive Impairment in Sturge-Weber Syndrome Recruiting NCT03047980 Phase 2, Phase 3 Sirolimus
22 MELABLOCK: A Clinical Trial on the Efficacy and Safety of Propranolol 80 mg in Melanoma Patients Not yet recruiting NCT02962947 Phase 2, Phase 3 Propranolol;Placebo
23 Propranolol in Capillary Hemangiomas Terminated NCT00744185 Phase 2, Phase 3 propranolol treatment;placebo treatment
24 Efficacy and Safety of Propranolol Versus Acebutolol on the Proliferative Phase of Infantile Hemangioma Terminated NCT01743885 Phase 3 Acebutolol;Propanolol
25 Treatment of Resistant Port-wine Stains With Bosentan and Pulsed Dye Laser: a Pilot Study Unknown status NCT02317679 Phase 2 Bosentan
26 Nadolol for Proliferating Infantile Hemangiomas Completed NCT01010308 Phase 2 Nadolol
27 A Phase II Study of Imiquimod 5 % Cream for the Treatment of Hemangioma in Infancy Completed NCT00601016 Phase 2 Imiquimod 5% cream
28 Topical Timolol Gel for the Treatment of Infantile Hemangiomas Completed NCT02145884 Phase 2 timolol maleate 0.5% gel
29 Study in Infants With Infantile Hemangioma to Compare Propranolol Gel to Placebo Completed NCT01512173 Phase 2 propranolol gel;Placebo
30 Comparative Study of the Use of Beta Blocker and Oral Corticosteroid in the Treatment of Infantile Hemangioma Completed NCT01072045 Phase 2 Propranolol;Prednisone
31 Measurement Skin Temperature During Pulsed Laser Exposure Completed NCT00540917 Phase 2
32 The Effects of Aldara as an Adjunct to Laser Treatment Completed NCT00979550 Phase 2 Imiquimod (Aldara);non-medicated petroleum cream
33 Study Comparing Onyx and TRUFILL in Brain Arteriovenous Malformations (AVMs) Completed NCT00857662 Phase 2
34 Treatment of Von Hippel-Lindau (VHL)-Related Hemangioblastoma With PTK787/ZK 222584 Completed NCT00052013 Phase 2 PTK787/ZK 222584
35 Phase II Trial of Sunitinib (SU011248) in Patients With Recurrent or Inoperable Meningioma Completed NCT00589784 Phase 2 Sunitinib
36 Thalidomide Reduces Arteriovenous Malformation Related Gastrointestinal Bleeding Completed NCT00389935 Phase 2 Thalidomide
37 Efficacy and Safety Study of Topical Rapamycin Associated With Pulsed Dye Laser in Patients With Sturge-Weber Syndrome Completed NCT02080624 Phase 2 Drug: Topical Rapamycin
38 Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma Completed NCT01154452 Phase 1, Phase 2 Gamma-Secretase Inhibitor RO4929097;Vismodegib
39 Efficacy, Safety and Pharmacokinetics of Topical Timolol in Infants With Infantile Hemangioma (IH) Recruiting NCT02913612 Phase 2 0.25% Timolol Maleate Gel Forming Solution;0.5% Timolol Maleate Gel Forming Solution
40 Topical Timolol for Infantile Hemangioma in Early Proliferative Phase Recruiting NCT02731287 Phase 2 Timolol;Placebo
41 A Study to Compare Vincristine to Sirolimus for Treatment of High Risk Vascular Tumors Recruiting NCT02110069 Phase 2 Vincristine;Sirolimus
42 A Phase I/II Trial for Intravitreous Treatment of Severe Ocular Von Hippel-Lindau Disease Using a Combination of the PDGF Antagonist E10030 and the VEGF Antagonist Ranibizumab Recruiting NCT02859441 Phase 1, Phase 2 Ranibizumab;E10030
43 A Safety and Efficacy Trial of Circumferential Anal Canal Radiofrequency Ablation for High-Grade Anal Intraepithelial Neoplasia Using the BARRX™ Anorectal Wand Recruiting NCT03302858 Phase 2
44 Prospective Evaluation of the Efficacy of Sirolimus (Rapamune®) in the Treatment of Severe Arteriovenous Malformations Recruiting NCT02042326 Phase 2 Sirolimus
45 Trametinib in Treating Patients With Epithelioid Hemangioendothelioma That Is Metastatic, Locally Advanced, or Cannot Be Removed by Surgery Recruiting NCT03148275 Phase 2 Trametinib
46 Proton Radiotherapy for Primary Central Nervous System Tumours in Adults Recruiting NCT02797366 Phase 2
47 Sirolimus Versus Sirolimus Plus Prednisolone for Kaposiform Hemangioendothelioma With Kasabach-Merritt Syndrome Recruiting NCT03188068 Phase 2 Sirolimus;Prednisolone
48 Gemcitabine Hydrochloride With or Without Pazopanib Hydrochloride in Treating Patients With Refractory Soft Tissue Sarcoma Recruiting NCT01532687 Phase 2 Gemcitabine Hydrochloride;Pazopanib Hydrochloride
49 Efficacy of a Timolol Nasal Spray as a Treatment for Epistaxis in Hereditary Hemorrhagic Telangiectasia (HHT) - (TEMPO) Active, not recruiting NCT02484716 Phase 2 Timolol nasal spray;Placebo nasal spray
50 Trial to Evaluate the Safety of TTAC-0001(Tanibirumab) in Recurrent Glioblastoma Active, not recruiting NCT03033524 Phase 2 TTAC-0001

Search NIH Clinical Center for Hemangioma

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: hemangioma

Genetic Tests for Hemangioma

Genetic tests related to Hemangioma:

id Genetic test Affiliating Genes
1 Hemangioma 29

Anatomical Context for Hemangioma

MalaCards organs/tissues related to Hemangioma:

39
Liver, Endothelial, Lung, Brain, Skin, Bone, Breast
LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Hemangioma:
id Tissue Anatomical CompartmentCell Relevance
1 Heart Cardinal Veins Venous Endothelial Cells Affected by disease

Publications for Hemangioma

Articles related to Hemangioma:

(show top 50) (show all 2463)
id Title Authors Year
1
Efficacy and rebound rates in propranolol-treated subglottic hemangioma: A literature review. ( 28833230 )
2017
2
Hemangioma of the urinary bladder: an atypical location. ( 28894340 )
2017
3
Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Diagnosis of Cavernous Hemangioma of Cavernous Sinus. ( 28479824 )
2017
4
A case of diffuse cavernous hemangioma of the appendix: laparoscopic surgery can facilitate diagnosis and treatment. ( 28054281 )
2017
5
Transanal total mesorectal excision as a surgical procedure for diffuse cavernous hemangioma of the rectum: A case report. ( 28846947 )
2017
6
Optimal Timing of Surgery for Intramedullary Cavernous Hemangioma of the Spinal Cord in Relation to Preoperative Motor Paresis, Disease Duration, and Tumor Volume and Location. ( 28660107 )
2017
7
Sudden death in a child caused by a giant cavernous hemangioma of the anterior mediastinum. ( 28886433 )
2017
8
The application of technetium-99m-red blood cell scintigraphy in the diagnosis of orbital cavernous hemangioma. ( 28692493 )
2017
9
Cardiac tamponade due to apixaban therapy in patient with unknown pericardial hemangioma. ( 28803417 )
2017
10
The expression and function of miR-424 in infantile skin hemangioma and its mechanism. ( 28928430 )
2017
11
Mixed Lymphangioma and Cavernous Hemangioma Within the Ulnar Nerve: A Case Report. ( 28391718 )
2017
12
When Faced With Anesthetizing an Infant With PHACE Syndrome: Watch Out for an Airway-Occluding Subglottic Hemangioma! ( 28767481 )
2017
13
Linear verrucous hemangioma of the upper limb: a rare case. ( 28633737 )
2017
14
Transoral ultrasonic surgery of pharyngolaryngeal giant hemangioma after ethylene-vinyl alcohol copolymer (Onyx) embolization. ( 28263419 )
2017
15
The pigment epithelium-derived factor (PEDF): an important potential therapeutic agent for infantile hemangioma. ( 28197761 )
2017
16
Dural-based giant cavernous hemangioma mimicking a meningioma: Lessons learnt. ( 28879931 )
2017
17
Capillary Hemangioma of the Tympanic Membrane and External Auditory Canal. ( 28106702 )
2017
18
Intradural-extramedullary capillary hemangioma with acute bleeding, case report and literature review. ( 28823662 )
2017
19
An Unusual Differential Diagnosis of Orbital Cavernous Hemangioma: Ancient Schwannoma. ( 28626414 )
2017
20
Spinal epidural capillary hemangioma: A rare case report with a review of literature. ( 28713627 )
2017
21
A Case of Retinal Cavernous Hemangioma Diagnosed with Spectral Domain Optical Coherence Tomography. ( 28534341 )
2017
22
The Art of Mimicry: Anterior Clinoid Dural-Based Cavernous Hemangioma Mistaken for a Meningioma. ( 28214640 )
2017
23
The role of CT myelography in sparing the spinal cord during definitive radiotherapy in vertebral hemangioma. ( 28834112 )
2017
24
Intradural Extramedullary Capillary Hemangioma In the Upper Thoracic Spine with Simultaneous Extensive Arachnoiditis. ( 28704911 )
2017
25
Capillary Hemangioma of Thoracic Spinal Cord: PET/CT and MR Findings. ( 28195909 )
2017
26
A Giant Cavernous Hemangioma of the Left Atrioventricular Groove. ( 28409047 )
2017
27
Intramuscular hemangioma causing periosteal reaction and cortical hypertrophy misdiagnosed as osteoid osteoma. ( 28388514 )
2017
28
Optical Coherence Tomography Angiography Features of Iris Racemose Hemangioma in 4 Cases. ( 28910426 )
2017
29
Rapidly enlarging acquired capillary hemangioma of the eyelid. ( 28400395 )
2017
30
Sturge-Weber Syndrome with Choroidal Hemangioma. ( 28584769 )
2017
31
Subcutaneous Lobular Capillary Hemangioma on 68Ga-PSMA PET/CT. ( 28114225 )
2017
32
Pneumocytoma (sclerosing hemangioma), a potential pitfall. ( 28398699 )
2017
33
Cavernous hemangioma of the orbit: an unusual acute presentation. ( 28769595 )
2017
34
Tricuspid Valve Hemangioma Associated with Hypoplastic Left Heart Syndrome Presenting as Sudden Infant Death Syndrome. ( 28272668 )
2017
35
Clinical-radiological-pathological correlation of cavernous sinus hemangioma: Incremental value of diffusion-weighted imaging. ( 28932362 )
2017
36
Gastric Hemangioma Treated with Argon Plasma Coagulation in a Newborn Infant. ( 28730139 )
2017
37
Optical Coherence Tomography Angiography of Retinal Cavernous Hemangioma. ( 28423387 )
2017
38
Intratumoral coagulation by radiofrequency ablation facilitated the laparoscopic resection of giant hepatic hemangioma: a surgical technique report of two cases. ( 28881707 )
2017
39
Rare cause for hemoptysis in an adolescent: Bronchial capillary hemangioma. ( 28165678 )
2017
40
Nasal Lobular Capillary Hemangioma as a Complication after an Endoscopic Transsphenoidal Gonadotrophin-Producing Pituitary Adenoma Resection. ( 28326242 )
2017
41
Challenging Pitfalls and Mimickers in Diagnosing Anastomosing Capillary Hemangioma of the Kidney: Case Report and Literature Review. ( 28286335 )
2017
42
A Case of Giant Intradural Extramedullary Capillary Hemangioma. ( 28091424 )
2017
43
Spitz Nevus Intermingling With Hemangioma, Angiomatoid Spitz Nevus, Angiotropism, and Vascular Co-option Viewed With Differing Availability Heuristics. ( 28398920 )
2017
44
Quiescent Volcano-Chest Wall Hemangioma. ( 28827912 )
2017
45
Anastomosing Hemangioma of the Ovary: A Clinicopathological Study of Six Cases with Stromal Luteinization. ( 28050796 )
2017
46
Debulking surgery for venous hemangioma arising from the epicardium: report of a case. ( 28403869 )
2017
47
Spinal epidural cavernous hemangioma: case report. ( 28637111 )
2017
48
Utility of the Hemangioma Severity Scale as a Triage Tool and Predictor of Need for Treatment. ( 27981617 )
2017
49
Optical Coherence Tomography Angiography of Retinal Cavernous Hemangioma. ( 28810047 )
2017
50
An update of 77 cases diagnosed as oral hemangiomas based on GLUT-1 positivity. ( 28545938 )
2017

Variations for Hemangioma

Expression for Hemangioma

Search GEO for disease gene expression data for Hemangioma.

Pathways for Hemangioma

Pathways related to Hemangioma according to GeneCards Suite gene sharing:

(show all 23)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.18 ANGPT2 FGF2 FLT4 KDR KRAS SLC2A1
2 12.54 CYCS FGF2 KRAS SLC2A1 VEGFA
3
Show member pathways
12.44 CYCS FGF2 FLT4 KDR KRAS VEGFA
4 12.4 ANGPT2 FGF2 FLT4 KDR KRAS TEK
5
Show member pathways
12.28 FGF2 FLT4 KDR VEGFA
6
Show member pathways
12.23 FLT4 KDR KRAS VEGFA
7
Show member pathways
12.2 ANGPT2 FGF2 FLT4 KDR KRAS KRIT1
8 12.18 FGF2 KDR KRAS VEGFA
9
Show member pathways
12.09 ANGPT2 KRAS PECAM1 TEK
10
Show member pathways
12.08 FGF2 KDR KRAS VEGFA
11 11.88 FGF2 KDR PROX1 VEGFA
12 11.81 ANGPT2 FGF2 FLT4 KDR TEK
13
Show member pathways
11.74 FLT4 KDR VEGFA
14
Show member pathways
11.69 FLT4 KDR KRAS
15 11.66 FGF2 SLC2A1 VEGFA
16 11.66 ANGPT2 SLC2A1 TEK VEGFA
17 11.41 ACTC1 FGF2 KDR
18 11.36 FGF2 KDR VEGFA
19 11.32 FGF2 KDR VEGFA
20 11.18 ANGPT2 SLC2A1 VEGFA
21 11.11 KDR SLC2A1 VEGFA
22 11.11 ANGPT2 FGF2 FLT4 KDR PECAM1 PROX1
23 10.84 FGF2 KDR TEK VEGFA

GO Terms for Hemangioma

Cellular components related to Hemangioma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.97 ANGPT2 ANTXR1 CD34 DIO3 FLT4 KDR
2 external side of plasma membrane GO:0009897 9.56 ANTXR1 CD34 PDPN PECAM1
3 cell periphery GO:0071944 9.13 CD34 LYVE1 PECAM1
4 membrane raft GO:0045121 9.02 KDR KRAS PECAM1 SLC2A1 TEK

Biological processes related to Hemangioma according to GeneCards Suite gene sharing:

(show all 36)
id Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 9.95 ACTC1 FLT4 KDR TEK VEGFA
2 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.93 FGF2 FLT4 KDR TEK
3 peptidyl-tyrosine phosphorylation GO:0018108 9.88 FGF2 FLT4 KDR TEK
4 negative regulation of angiogenesis GO:0016525 9.83 ANGPT2 KRIT1 TEK
5 leukocyte migration GO:0050900 9.83 ANGPT2 CD34 KRAS PECAM1 TEK
6 vascular endothelial growth factor receptor signaling pathway GO:0048010 9.82 FLT4 KDR VEGFA
7 lung development GO:0030324 9.8 NKX2-1 PDPN PROX1 VEGFA
8 positive regulation of MAP kinase activity GO:0043406 9.79 FGF2 KRAS VEGFA
9 positive regulation of protein phosphorylation GO:0001934 9.77 FLT4 KDR KRAS TEK VEGFA
10 positive regulation of angiogenesis GO:0045766 9.73 ANGPT2 CD34 FGF2 KDR TEK VEGFA
11 angiogenesis GO:0001525 9.7 ANGPT2 FGF2 FLT4 KDR KRIT1 TEK
12 negative regulation of endothelial cell apoptotic process GO:2000352 9.69 KDR KRIT1 TEK
13 epithelial tube branching involved in lung morphogenesis GO:0060441 9.67 KRAS NKX2-1
14 hyaluronan catabolic process GO:0030214 9.67 FGF2 LYVE1
15 positive regulation of positive chemotaxis GO:0050927 9.66 KDR VEGFA
16 lymph vessel development GO:0001945 9.66 FLT4 PROX1
17 positive regulation of cellular component movement GO:0051272 9.65 PDPN VEGFA
18 positive regulation of vasculogenesis GO:2001214 9.65 CD34 KDR
19 positive regulation of focal adhesion assembly GO:0051894 9.65 KDR TEK VEGFA
20 stem cell proliferation GO:0072089 9.64 CD34 FGF2
21 positive regulation of protein kinase C signaling GO:0090037 9.63 FLT4 VEGFA
22 cellular response to vascular endothelial growth factor stimulus GO:0035924 9.63 FLT4 KDR VEGFA
23 vascular endothelial growth factor signaling pathway GO:0038084 9.61 FLT4 KDR
24 skeletal muscle thin filament assembly GO:0030240 9.6 ACTC1 PROX1
25 endothelium development GO:0003158 9.59 CD34 KDR
26 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway GO:0038033 9.58 KDR VEGFA
27 cell migration involved in sprouting angiogenesis GO:0002042 9.58 FGF2 KDR VEGFA
28 glomerulus vasculature development GO:0072012 9.57 ANGPT2 TEK
29 Tie signaling pathway GO:0048014 9.54 ANGPT2 TEK
30 glomerular endothelium development GO:0072011 9.52 CD34 PECAM1
31 lymphangiogenesis GO:0001946 9.5 FLT4 PDPN PROX1
32 positive regulation of endothelial cell migration GO:0010595 9.35 FLT4 KDR PROX1 TEK VEGFA
33 positive regulation of endothelial cell proliferation GO:0001938 9.1 FGF2 FLT4 KDR PROX1 TEK VEGFA
34 signal transduction GO:0007165 10.28 ANGPT2 ANTXR1 CD34 FGF2 KRAS LYVE1
35 positive regulation of cell proliferation GO:0008284 10.03 FGF2 FLT4 KDR KRAS PROX1 VEGFA
36 positive regulation of gene expression GO:0010628 10 ACTC1 CD34 KRAS NKX2-1 VEGFA

Molecular functions related to Hemangioma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 transmembrane receptor protein tyrosine kinase activity GO:0004714 9.33 FLT4 KDR TEK
2 vascular endothelial growth factor-activated receptor activity GO:0005021 9.26 FLT4 KDR
3 protein tyrosine kinase activity GO:0004713 9.26 FGF2 FLT4 KDR TEK
4 growth factor binding GO:0019838 8.8 FLT4 KDR TEK

Sources for Hemangioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
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44 MGI
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48 NDF-RT
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52 Novoseek
54 OMIM
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59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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