MCID: HMN013
MIFTS: 51

Hemangiopericytoma malady

Summaries for Hemangiopericytoma

Sources:
8Disease Ontology, 43NIH Rare Diseases, 64Wikipedia, 33MalaCards
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NIH Rare Diseases:43 Hemangiopericytoma is a term used to described a group of tumors that are derived from pericytes, the cells normally arranged along specific types of blood vessels called capillaries and venules. these types of tumors are typically slow-growing, may be either benign (non-cancerous) or malignant (cancerous), and may occur anywhere in the body. last updated: 11/19/2013

MalaCards: Hemangiopericytoma, also known as hemangiopericytoma, malignant, is related to synovial sarcoma and adenoma. An important gene associated with Hemangiopericytoma is DES (desmin), and among its related pathways are Striated Muscle Contraction and EGFR Signaling Pathway. The compounds estrogen and glycogen have been mentioned in the context of this disorder. Related mouse phenotypes are reproductive system and embryogenesis.

Disease Ontology:8 A soft tissue cancer that is a soft tissue sarcoma and originates in the pericytes in the walls of capillaries.

Wikipedia:64 A hemangeopericytoma (HPC) is a type of soft tissue sarcoma that originates in the pericytes in the... more...

Aliases & Classifications for Hemangiopericytoma

Sources:
8Disease Ontology, 43NIH Rare Diseases, 10DISEASES, 45Novoseek, 61UMLS, 57SNOMED-CT, 35MeSH, 40NCIt
See all sources

Aliases & Descriptions:

hemangiopericytoma 8 43 10 45 61
hemangiopericytoma, malignant 8 61
haemangiopericytic meningioma 8
malignant hemangiopericytoma 8


External Ids:

Disease Ontology8 DOID:264
MeSH35 D006393
SNOMED-CT57 134335004, 36060005
NCIt40 C3087

Related Diseases for Hemangiopericytoma

Sources:
17GeneCards, 18GeneDecks
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Diseases in the Hemangiopericytoma family:

adult malignant hemangiopericytoma

Diseases related to Hemangiopericytoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 222)
idRelated DiseaseScoreTop Affiliating Genes
1synovial sarcoma30.2CDH1, MUC1, IGF2, SSX2, DES, MDM2
2adenoma30.2ACTC1, CDH1, MUC1, IGF2, RB1, MGMT
3infantile myofibromatosis30.2DES
4hemangioendothelioma30.0CD34
5fibrous meningioma30.0MUC1, NF2, S100B
6endometrial stromal sarcoma30.0ACTC1, DES, VIM
7angiosarcoma30.0ACTC1, CD34, MUC1, VIM
8benign meningioma30.0EPB41L3, NF2, MDM2
9fibrous histiocytoma30.0ACTC1, CD34, DES, F13A1, S100B, VIM
10neurofibromatosis29.8NGFR, NF2, S100B
11smooth muscle tumor29.8ACTC1, IGF2, DES, S100A1, S100B, VIM
12papillary carcinoma29.8ACTC1, CDH1, MUC1, E2F1, S100A1
13gastrointestinal stromal tumor29.8ACTC1, CD34, NF2, DES, E2F1, S100A1
14transitional cell carcinoma29.8CDH1, RB1, MDM2
15solitary fibrous tumor10.7
16hypoglycemia10.5
17retroperitoneal hemangiopericytoma10.5
18breast hemangiopericytoma10.4
19kidney hemangiopericytoma10.4
20osteomalacia10.3
21meninges hemangiopericytoma10.3
22heart malignant hemangiopericytoma10.3
23oncogenic osteomalacia10.3
24malignant mediastinum hemangiopericytoma10.2
25conventional malignant hemangiopericytoma10.2
26childhood malignant hemangiopericytoma10.2
27adult intracranial malignant hemangiopericytoma10.2
28myofibroma10.1
29adult malignant hemangiopericytoma10.1
30arteriovenous malformation10.0
31angiomatous meningioma10.0
32soft tissue sarcoma10.0
33epithelioid hemangioendothelioma10.0
34lymphangioleiomyomatosis10.0DES
35neuroblastoma10.0NGFR
36cutaneous fibrous histiocytoma10.0CD34
37dermatofibrosarcoma10.0MDM2
38fasciitis10.0ACTC1
39dermatitis10.0F13A1
40hepatitis b10.0E2F1
41ductal carcinoma in situ10.0CDH1
42hepatoblastoma10.0IGF2
43adenomatoid tumor10.0VIM
44malignant fibroxanthoma10.0CD34
45histiocytosis10.0S100B
46pheochromocytoma10.0NGFR
47esophageal cancer10.0CDH1
48laryngeal carcinoma10.0RB1
49sertoli-leydig cell tumor10.0MUC1
50giant cell glioblastoma10.0MDM2

Graphical network of the top 20 diseases related to Hemangiopericytoma:



Diseases related to hemangiopericytoma

Clinical Features for Hemangiopericytoma

Drugs & Therapeutics for Hemangiopericytoma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

Search CenterWatch for Hemangiopericytoma

Drug clinical trials:

Search ClinicalTrials for Hemangiopericytoma

Search NIH Clinical Center for Hemangiopericytoma

Search CenterWatch for Hemangiopericytoma

Genetic Tests for Hemangiopericytoma

Anatomical Context for Hemangiopericytoma

Animal Models for Hemangiopericytoma or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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Publications for Hemangiopericytoma

Sources:
51PubMed
See all sources

Articles related to Hemangiopericytoma:

(show top 50)    (show all 535)
idTitleAuthorsYear
1
Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein. (23575898)
2013
2
Cerebello-pontine angle hemangiopericytoma: an orphan differential diagnosis. (23182178)
2013
3
Metastasis of intracranial meningeal hemangiopericytoma to thoracic spine 17A years after surgical excision: a case report. (23943153)
2013
4
Intracranial Hemangiopericytoma, our experience in 30 years: a series of 43 cases. A case series and review of the literature. (24239740)
2013
5
Anaplastic hemangiopericytoma manifesting as a rapidly enlarging extracranial mass lesion. (22639689)
2012
6
Malignant hemangiopericytoma of the condyle. (22337457)
2012
7
Intracranial meningeal hemangiopericytoma metastatic to the scapula. (22229602)
2012
8
Central nervous system hemangiopericytoma, retrospective four year pathology case series. (23038887)
2012
9
Sinonasal-type hemangiopericytoma of the nasal cavity and paranasal sinus. (21656202)
2012
10
F-18 FDG PET/CT findings of primary sinonasal hemangiopericytoma: rare location in a young adult patient. (21552030)
2011
11
Preoperative radiation therapy in the management of recurrent orbital hemangiopericytoma. (21242853)
2011
12
Primary intracranial hemangiopericytoma presenting as hemiparkinsonism. (21473175)
2011
13
Response to trabectedin treatment in a highly pretreated patient with an advanced meningeal hemangiopericytoma. (20622667)
2010
14
Hemangiopericytoma: an unusual cause of peritoneal carcinomatosis. (19602469)
2009
15
Renal hemangiopericytoma: case report and review of the literature. (18387402)
2008
16
Cytomorphologic findings of hemangiopericytoma of the meninges: a case report. (17883098)
2007
17
D2-40 staining in sinonasal-type hemangiopericytoma--further evidence of distinction from conventional hemangiopericytoma and solitary fibrous tumor. (16362413)
2006
18
Recurrent superior mediastinal primary hemangiopericytoma 23 years after the complete initial excision: a case report. (16838049)
2006
19
Hemangiopericytoma in the eyelid of a horse. (16847005)
2006
20
Bone metastasis of intracranial meningeal hemangiopericytoma. (15990973)
2005
21
Hemangiopericytoma in pregnancy: a case report. (15980981)
2005
22
Distinction of endometrial stromal sarcomas from 'hemangiopericytomatous' tumors using a panel of immunohistochemical stains. (15309019)
2005
23
Fat-containing variant of solitary fibrous tumor (lipomatous hemangiopericytoma) arising on surface of kidney. (15667897)
2005
24
Lipomatous hemangiopericytoma of the head and neck: immunohistochemical and DNA ploidy analyses. (15162357)
2004
25
A novel case of synovial sarcoma of the kidney: impact of SS18/SSX analysis of renal hemangiopericytoma-like tumors. (15163009)
2004
26
Oncogenic hypophosphatemic osteomalacia associated with a nasal hemangiopericytoma. (17043447)
2003
27
Solitary fibrous tumor of the oral mucosa--morphological and immunohistochemical profile in the differential diagnosis with hemangiopericytoma. (12676265)
2003
28
Primary hemangiopericytoma of the trachea. (12963242)
2003
29
Malignant hemangiopericytoma: a clinical overview and case study. (12629936)
2003
30
Intracranial hemangiopericytoma with extracranial metastasis occurring after 22 years. (12160309)
2002
31
Sinonasal hemangiopericytoma. (11913055)
2002
32
Isolated pelvic perfusion for pelvic hemangiopericytoma. (11816000)
2002
33
Intraocular hemangiopericytoma. A case report. (11528266)
2001
34
Hemangiopericytoma of the seminal vesicle presenting with hypoglycemia. (11490268)
2001
35
Hemangiopericytoma of the buccal region: a case report. (11289179)
2001
36
True hemangiopericytoma of the nasal cavity. (11300947)
2001
37
Intracranial infantile hemangiopericytoma. (10789910)
2000
38
Myofibroblastoma of the breast with hemangiopericytoma-like pattern and pleomorphic lipoma-like areas. Report of a case with diagnostic and histogenetic considerations. (10337665)
1999
39
Primary hemangiopericytoma of the superior mediastinum: a case report. (9828288)
1998
40
Hemangiopericytoma of the lacrimal sac. (9869805)
1998
41
Childhood hemangiopericytoma. (9544226)
1998
42
Endoscopic resection of a recurrent sinonasal hemangiopericytoma. (9282253)
1997
43
Orbital hemangiopericytoma: clinical and morphologic features. (9372720)
1997
44
External carotid artery ligation for life-threatening hemorrhage in exsanguinating orbital facial congenital hemangiopericytoma. (9269983)
1997
45
Primary pulmonary malignant hemangiopericytoma associated with coagulopathy. (9307488)
1997
46
Hemangiopericytoma of renal sinus expanding to the renal hilum: an unusual presentation causes misinterpretation as transitional cell carcinoma. (8878806)
1996
47
Hemangiopericytoma: a rare pineal mass. (8957805)
1996
48
Case report: MR appearance of hemangiopericytoma of the thigh. (8988508)
1996
49
Endodermal sinus tumor (yolk sac tumor), seminoma and hemangiopericytoma. Rare primary mediastinal tumors. A report on the course of the disease in nine patients. (6158129)
1980
50
Ultrastructure of a hemangiopericytoma and a glomus tumor. (4303166)
1968

Genetic Variations for Hemangiopericytoma

Expression for genes affiliated with Hemangiopericytoma

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hemangiopericytoma

Search GEO for disease gene expression data for Hemangiopericytoma.

Pathways for genes affiliated with Hemangiopericytoma

Sources:
38NCBI BioSystems Database, 54Reactome, 56SinoBiological, 12EMD Millipore, 30KEGG, 52QIAGEN, 4Cell Signaling Technology
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Compounds for genes affiliated with Hemangiopericytoma

Sources:
45Novoseek, 24HMDB, 50PharmGKB, 60Tocris Bioscience, 11DrugBank, 29IUPHAR, 2BitterDB
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Compounds related to Hemangiopericytoma according to GeneCards/GeneDecks:

(show top 50)    (show all 114)
idCompoundScoreTop Affiliating Genes
1estrogen4510.8F13A1
2glycogen45 2411.6IGF2, ACTC1, MDM2
3reticulin4510.6VIM, DES, MUC1, ACTC1
4orcein4510.5VIM, ACTC1, S100B, DES
5creatinine4510.4ACTC1, CDH1, IGF2, PTGDS
62-methoxyethanol4510.4S100A1, VIM, IGF2, ACTC1
7s 1004510.3VIM, F13A1, DES, MUC1, ACTC1, S100B
8mucicarmine4510.3S100B, VIM, DES, MUC1, S100A1, ACTC1
9etoposide45 50 60 1113.2S100B, VIM, RB1, IGF2, CDH1, MDM2
10biotin45 11 2412.2ACTC1, MUC1, DES, RB1, VIM, S100A1
11progestin4510.2VIM, DES, CDH1, MUC1, IGF2
12dexamethasone45 50 29 1113.2MGMT, S100B, CDH1, IGF2, RB1, MDM2
13serine4510.2S100B, NF2, CDH1, DES, E2F1
14p0024510.2CDH1, MGMT, MDM2, RB1, IGF2, DES
15silver4510.2S100A1, PTGDS, F13A1, CDH1, DES, CD34
16paclitaxel45 50 1112.2MDM2, S100B, CDH1, IGF2, E2F1, RB1
17adriamycin4510.1VIM, E2F1, MDM2, RB1, DES, MUC1
18thymidylate4510.1MDM2, MGMT, E2F1, RB1, VIM, CDH1
19b 7234510.1MUC1, CDH1, ACTC1, DES, VIM, S100B
20formaldehyde45 2411.1MUC1, ACTC1, VIM, S100B, MGMT, RB1
215-aza-2deoxycytidine4510.0SSX2, MGMT, CDH1, MDM2, EPB41L3, IGF2
22azathioprine45 50 2 1113.0VIM, DES, IGF2, MGMT, CDH1
23methotrexate45 50 1112.0MUC1, RB1, MDM2, MGMT, VIM, CDH1
245fluorouracil4510.0RB1, CDH1, MGMT, MDM2, E2F1, IGF2
25chloramphenicol45 2 1112.0MUC1, MGMT, VIM, S100B, E2F1, IGF2
26vincristine45 50 1112.0RB1, MGMT, E2F1, VIM
27actinomycin d4510.0RB1, DES, IGF2, MUC1, E2F1, VIM
28estradiol45 11 2412.0MDM2, RB1, DES, IGF2, MUC1, E2F1
29rapamycin4510.0MDM2, E2F1, NF2, IGF2, CDH1, VIM
30steroid4510.0ACTC1, DES, NGFR, MDM2, RB1, E2F1
31doxorubicin45 50 1112.0MGMT, VIM, CDH1, E2F1, DES, RB1
3212-o-tetradecanoylphorbol 13-acetate459.9CD34, CDH1, MUC1, NGFR, DES, RB1
33calcium45 50 11 2412.9ACTC1, S100B, MUC1, NGFR, DES, F13A1
34cyclic amp45 2410.9RB1, VIM, CDH1, MUC1, NGFR, DES
35matrigel459.9ACTC1, CDH1, MUC1, NGFR, RB1, VIM
36hematoxylin459.9VIM, S100B, S100A1, F13A1, DES, NGFR
37iron45 2410.9F13A1, S100A1, DES, ACTC1, MDM2, S100B
38oligonucleotide459.8VIM, MGMT, E2F1, MDM2, RB1, F13A1
39agar459.8VIM, MDM2, RB1, NF2, IGF2, NGFR
40nitric oxide45 11 2411.8MGMT, NGFR, E2F1, MDM2, MUC1, DES
41testosterone45 60 11 2412.7MUC1, ACTC1, VIM, PTGDS, S100B, RB1
42crcs459.7MUC1, RB1, MGMT, CDH1
43thymidine45 2410.7MGMT, EPB41L3, DES, NGFR, RB1, MDM2
44cysteine459.6MDM2, NF2, IGF2, VIM, NGFR, MUC1
45cisplatin45 50 60 1112.6RB1, MDM2, MGMT, E2F1, MUC1, IGF2
46tyrosine459.4DES, RB1, E2F1, S100A1, MDM2, NF2
47vegf459.4IGF2, DES, F13A1, RB1, MDM2, MGMT
48retinoic acid45 2410.4VIM, MUC1, CDH1, S100B, S100A1, E2F1
49paraffin459.3MGMT, MDM2, RB1, F13A1, DES, NF2
50progesterone45 60 29 11 2413.0MDM2, MGMT, E2F1, S100A1, S100B, VIM

GO Terms for genes affiliated with Hemangiopericytoma

Sources:
16Gene Ontology
See all sources

Cellular components related to Hemangiopericytoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1Rb-E2F complexGO:0351899.9RB1, E2F1
2perinuclear region of cytoplasmGO:0484719.9PTGDS, CD34, CDH1, NF2, S100B

Biological processes related to Hemangiopericytoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of transcription involved in G1/S transition of mitotic cell cycleGO:07193010.3RB1, E2F1
2regulation of cysteine-type endopeptidase activity involved in apoptotic processGO:04328110.3CDH1, NGFR, MGMT
3negative regulation of cell-cell adhesionGO:02240810.2CDH1, NF2
4muscle filament slidingGO:03004910.2ACTC1, DES, VIM
5cellular response to hypoxiaGO:07145610.0S100B, E2F1, MDM2
6response to drugGO:0424939.7ACTC1, CDH1, MDM2, MGMT

Molecular functions related to Hemangiopericytoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of cytoskeletonGO:00520010.2EPB41L3, DES, VIM
2S100 protein bindingGO:0445489.9S100A1, S100B
3identical protein bindingGO:0428029.8DES, RB1, MDM2, S100A1, S100B, VIM
4protein bindingGO:0055158.9MDM2, E2F1, S100A1, S100B, VIM, RB1

Products for genes affiliated with Hemangiopericytoma

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  • Proteins
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Sources for Hemangiopericytoma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet