MCID: HMN013
MIFTS: 55

Hemangiopericytoma malady

Rare diseases, Cancer diseases categories
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Summaries for Hemangiopericytoma

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NIH Rare Diseases:42 Hemangiopericytoma is a term used to described a group of tumors that are derived from pericytes, the cells normally arranged along specific types of blood vessels called capillaries and venules. these types of tumors are typically slow-growing, may be either benign (non-cancerous) or malignant (cancerous), and may occur anywhere in the body. last updated: 11/19/2013

MalaCards based summary: Hemangiopericytoma, also known as hemangiopericytoma, malignant, is related to infantile myofibromatosis and fibrous meningioma. An important gene associated with Hemangiopericytoma is DES (desmin), and among its related pathways are Aurora B signaling and Response to elevated platelet cytosolic Ca2+. The compounds eosin and toluidine have been mentioned in the context of this disorder. Affiliated tissues include bone, lung and breast, and related mouse phenotypes are muscle and cardiovascular system.

Disease Ontology:8 A soft tissue cancer that is a soft tissue sarcoma and originates in the pericytes in the walls of capillaries.

Wikipedia:65 A hemangiopericytoma (HPC) is a type of soft tissue sarcoma that originates in the pericytes in the... more...

Aliases & Classifications for Hemangiopericytoma

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Hemangiopericytoma, Aliases & Descriptions:

Name: Hemangiopericytoma 8 42 10 44 62
Hemangiopericytoma, Malignant 8 62
 
Haemangiopericytic Meningioma 8
Malignant Hemangiopericytoma 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases


External Ids:

Disease Ontology8 DOID:264
MeSH34 D006393
SNOMED-CT57 134335004, 36060005
NCIt39 C3087

Related Diseases for Hemangiopericytoma

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Diseases in the Hemangiopericytoma family:

Adult Malignant Hemangiopericytoma

Diseases related to Hemangiopericytoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 150)
idRelated DiseaseScoreTop Affiliating Genes
1infantile myofibromatosis31.0DES
2fibrous meningioma30.8MUC1
3liposarcoma30.5DES, VIM
4meningioma30.3IGF2, PTGDS, VIM, MUC1
5synovial sarcoma30.2DES, IGF2, VIM, MUC1
6mesenchymal chondrosarcoma30.0MUC1, VIM, DES
7chondrosarcoma30.0DES, VIM, MUC1
8endometrial stromal sarcoma30.0ACTC1, VIM, DES
9angiosarcoma29.9VIM, MUC1, ACTC1
10adenoma29.9ACTC1, MUC1, IGF2
11papillary carcinoma29.8MUC1, ACTC1
12gastrointestinal stromal tumor29.7DES, VIM, ACTC1
13fibrous histiocytoma29.6DES, F13A1, VIM, ACTC1
14sarcoma29.5DES, IGF2, F13A1, VIM, MUC1, ACTC1
15leiomyoma29.4ACTC1, VIM, IGF2, DES
16neurofibroma29.4F13A1, VIM, MUC1, ACTC1
17meninges hemangiopericytoma10.7
18meningitis10.7
19solitary fibrous tumor10.7
20hypoglycemia10.5
21syringoma10.5MUC1
22retroperitoneal hemangiopericytoma10.5
23hidradenoma10.5MUC1
24adenomatoid tumor10.4VIM
25cystadenocarcinoma10.4MUC1
26osteomalacia10.4
27mediastinitis10.4
28macular holes10.3PTGDS
29hepatitis10.3
30desmoplastic small round cell tumor10.3MUC1, DES
31kidney hemangiopericytoma10.3
32malignant mediastinum hemangiopericytoma10.3
33fasciitis10.3ACTC1
34choroid plexus papilloma10.3IGF2, MUC1
35perineurioma10.3VIM, MUC1
36oncogenic osteomalacia10.3
37alveolar soft part sarcoma10.2DES, VIM
38clear cell ependymoma10.2VIM, MUC1
39granular cell tumor10.2DES, VIM
40epithelioid sarcoma10.2VIM, MUC1
41phyllode tumor10.2VIM, IGF2
42secretory meningioma10.2VIM, MUC1
43childhood malignant hemangiopericytoma10.2
44heart malignant hemangiopericytoma10.2
45adult intracranial malignant hemangiopericytoma10.2
46breast hemangiopericytoma10.2
47cervicitis10.2
48uterine fibroid10.2DES, IGF2
49ependymoma10.2MUC1, VIM
50oxyphilic adenoma10.2MUC1, VIM

Graphical network of the top 20 diseases related to Hemangiopericytoma:



Diseases related to hemangiopericytoma

Symptoms for Hemangiopericytoma

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Drugs & Therapeutics for Hemangiopericytoma

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Drug clinical trials:

Search ClinicalTrials for Hemangiopericytoma

Search NIH Clinical Center for Hemangiopericytoma

Genetic Tests for Hemangiopericytoma

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Anatomical Context for Hemangiopericytoma

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MalaCards organs/tissues related to Hemangiopericytoma:

32
Bone, Lung, Breast, Liver, Tongue, Kidney, Pineal, Pituitary, Heart, Ovary, Spleen, Spinal cord, Adipocyte, Skin, Uterus, Eye, Brain, Smooth muscle, Small intestine, Colon, Salivary gland, Adrenal gland, Prostate, Testis, Trachea

Animal Models for Hemangiopericytoma or affiliated genes

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MGI Mouse Phenotypes related to Hemangiopericytoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053698.3ACTC1, VIM, IGF2, DES
2MP:00053857.5DES, IGF2, F13A1, VIM, ACTC1
3MP:00107687.1DES, IGF2, F13A1, PTGDS, VIM, ACTC1
4MP:00053766.7ACTC1, DES, IGF2, F13A1, PTGDS, VIM

Publications for Hemangiopericytoma

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Articles related to Hemangiopericytoma:

(show top 50)    (show all 550)
idTitleAuthorsYear
1
Intracranial infantile hemangiopericytoma. (24905842)
2014
2
Intradural extra medullary hemangiopericytoma of dorsal spine. (25059986)
2014
3
Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein. (23575898)
2013
4
Endoscopic Resection of Sinonasal Hemangiopericytoma following Preoperative Embolisation: A Case Report and Literature Review. (23738175)
2013
5
Somatostatin receptor molecular imaging for metastatic intracranial hemangiopericytoma. (24212443)
2013
6
Clinical analysis of intracranial hemangiopericytoma. (24294454)
2013
7
Large hemangiopericytoma associated with arteriovenous malformations and dural arteriovenous fistulae. (22251512)
2011
8
Lipomatous hemangiopericytoma of the stomach: a case report and a review of literature. (22147987)
2011
9
Phase II study of subcutaneous octreotide in adults with recurrent or progressive meningioma and meningeal hemangiopericytoma. (21558077)
2011
10
Hemangiopericytoma in the trigone of the lateral ventricle. (21613766)
2011
11
Intradural hemangiopericytoma of the thoracic spine: a case report. (21641873)
2011
12
Hemangiopericytoma/Solitary fibrous tumor of the oral cavity. (21378362)
2011
13
Hemangiopericytoma: collision with meningioma and recurrence. (20198500)
2010
14
Concurrent Cochlear Implantation with Resection of Skull Base Hemangiopericytoma following Sudden Deafness in an Only Hearing Ear. (21311622)
2010
15
Hemangiopericytoma-solitary fibrous tumour of soft tissue: description of a case showing atypical histological features. (20731251)
2010
16
Inhibiting the VEGF-VEGFR pathway in angiosarcoma, epithelioid hemangioendothelioma, and hemangiopericytoma/solitary fibrous tumor. (20485168)
2010
17
Intradural hemangiopericytoma of the lumbar spine: a rare entity. (18768724)
2009
18
A case of metastatic hemangiopericytoma occurring 16 years after initial presentation: with special reference to the clinical behavior and treatment of metastatic hemangiopericytoma. (19755799)
2009
19
Sudden death due to undiagnosed intracranial hemangiopericytoma. (18520488)
2008
20
Hemangiopericytoma of the Breast: A Case Report. (21048916)
2008
21
Pulmonary lipomatous hemangiopericytoma: report of a rare tumor and comparison with solitary fibrous tumor. (17455098)
2007
22
Metastatic hemangiopericytoma of the skin treated with wide local excision and MGN-3. (16393616)
2006
23
D2-40 staining in sinonasal-type hemangiopericytoma--further evidence of distinction from conventional hemangiopericytoma and solitary fibrous tumor. (16362413)
2006
24
Bone metastasis of intracranial meningeal hemangiopericytoma. (15990973)
2005
25
Preoperative embolization in surgical treatment of a primary hemangiopericytoma of the rib: a case report. (15832008)
2005
26
Case 3. Oncogenic osteomalacia associated with hemangiopericytoma localized by octreotide scan. (15908675)
2005
27
Multiple extracranial metastases from a meningeal hemangiopericytoma and severe hypoglycemia: a case report]. (15227844)
2004
28
Sinonasal-type hemangiopericytoma: a clinicopathologic and immunophenotypic analysis of 104 cases showing perivascular myoid differentiation. (12766577)
2003
29
Oncogenic hypophosphatemic osteomalacia associated with a nasal hemangiopericytoma. (17043447)
2003
30
Solitary fibrous tumor of the oral mucosa--morphological and immunohistochemical profile in the differential diagnosis with hemangiopericytoma. (12676265)
2003
31
Cutaneous malignant hemangiopericytoma with unusual clinical behavior. (12081167)
2002
32
Case of primary malignant hemangiopericytoma of the heart expressing basement membrane-degradable enzymes. (12366815)
2002
33
Hemangiopericytoma of the parotid gland: CT and MR features. (11419156)
2001
34
Intraocular hemangiopericytoma. A case report. (11528266)
2001
35
Preoperative embolization in surgical treatment of mediastinal hemangiopericytoma. (10750792)
2000
36
Liver angiosarcoma and hemangiopericytoma after occupational exposure to vinyl chloride monomer. (10964802)
2000
37
Fine-needle aspiration cytology of hemangiopericytoma: report of two cases. (10945907)
2000
38
Hemangiopericytoma in children and infants. (10618624)
2000
39
Positron emission tomography in a case of intracranial hemangiopericytoma. (10348440)
1999
40
Cytogenetic, ras, and p53: studies in cases of canine neoplasms (hemangiopericytoma, mastocytoma, histiocytoma, chloroma). (9987918)
1999
41
Oncogenic osteomalacia secondary to a hemangiopericytoma of the hip: case report. (10047746)
1999
42
Hepatic and pulmonary metastases from a meningeal hemangiopericytoma and severe hypoglycemia due to abnormal secretion of insulin-like growth factor: a case report. (10326704)
1999
43
Hemangiopericytoma of the third ventricle. Case report. (9950509)
1999
44
Long-term survival after repetitive surgery for malignant hemangiopericytoma of the lung with subsequent systemic metastases: case report and review of the literature. (9477464)
1997
45
Primary orbital hemangiopericytoma: a case report. (9294920)
1997
46
Meningeal hemangiopericytoma metastatic to the heart. (8776772)
1996
47
Hemangiopericytoma of the masticator space. (8659939)
1996
48
Hemangiopericytoma of the uterus: an unusual cause of the postmenopausal metrorrhagia. (7572113)
1995
49
Giant retroperitoneal hemangiopericytoma. (7494778)
1995
50
Hemangiopericytoma of the uterus vs. hemangiopericytoma-like endometrial stromal sarcoma: a histopathological approach to differential diagnosis. (4054418)
1985

Variations for Hemangiopericytoma

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Expression for genes affiliated with Hemangiopericytoma

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Expression patterns in normal tissues for genes affiliated with Hemangiopericytoma

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Pathways for genes affiliated with Hemangiopericytoma

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Pathways related to Hemangiopericytoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Signaling by Aurora kinases37
Aurora C signaling37
9.6VIM, DES
2
Show member pathways
9.5F13A1, IGF2
39.2ACTC1, IGF2
4
Show member pathways
8.8ACTC1, VIM, DES
58.8ACTC1, VIM, DES
6
Show member pathways
8.7DES, IGF2, VIM, MUC1

Compounds for genes affiliated with Hemangiopericytoma

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Compounds related to Hemangiopericytoma according to GeneCards/GeneDecks:

(show top 50)    (show all 73)
idCompoundScoreTop Affiliating Genes
1eosin449.9VIM, MUC1
2toluidine449.9VIM, DES
3acetone449.8IGF2, MUC1
4phalloidin449.6DES, VIM
5adriamycin449.5DES, VIM, MUC1
6hyaluronic acid44 2410.5MUC1, VIM, DES
7azathioprine44 2 50 1112.5DES, IGF2, VIM
8gemfibrozil28 44 1111.5DES, VIM
9hydrocortisone44 2 61 1112.4MUC1, VIM, IGF2
1012-o-tetradecanoylphorbol 13-acetate449.4DES, VIM, MUC1
11folate449.4MUC1, VIM, IGF2
12agar449.4IGF2, VIM, MUC1
13chloramphenicol44 2 50 1112.4MUC1, VIM, IGF2
14silver449.3DES, F13A1, PTGDS
15butyrate449.3MUC1, VIM, IGF2
16tamoxifen44 50 28 1112.3IGF2, VIM, MUC1
17orcein449.2ACTC1, VIM, DES
18imatinib44 50 1111.2DES, IGF2, ACTC1
19progestin449.1MUC1, VIM, IGF2, DES
20dihydrotestosterone44 28 24 1112.1DES, IGF2, VIM, MUC1
21actinomycin d449.1DES, IGF2, VIM, MUC1
22estradiol44 24 1111.1MUC1, VIM, IGF2, DES
23forskolin44 50 1111.1MUC1, VIM, IGF2
242-methoxyethanol449.1IGF2, VIM, ACTC1
25ribonucleic acid449.1ACTC1, MUC1, IGF2
26matrigel449.0VIM, MUC1, ACTC1
27heparin44 28 24 1112.0VIM, F13A1, IGF2, DES
28histamine44 28 2410.9VIM, PTGDS, IGF2
29cysteine448.9DES, IGF2, VIM, MUC1
30actomyosin448.8ACTC1, VIM
31mucicarmine448.8DES, VIM, MUC1, ACTC1
32biotin44 24 1110.8ACTC1, MUC1, VIM, DES
33formaldehyde44 249.7DES, VIM, MUC1, ACTC1
34procollagen448.7ACTC1, VIM, F13A1, DES
35iron44 249.6ACTC1, VIM, F13A1, DES
36dexamethasone44 50 28 1111.6IGF2, VIM, MUC1, ACTC1
37glucose448.5ACTC1, MUC1, IGF2, DES
38glycogen44 249.3DES, IGF2, VIM, MUC1, ACTC1
39s 100448.3ACTC1, MUC1, VIM, F13A1, DES
40reticulin448.3DES, F13A1, VIM, MUC1, ACTC1
41b 723448.3DES, F13A1, VIM, MUC1, ACTC1
42hematoxylin448.3ACTC1, MUC1, VIM, F13A1, DES
43calcium44 50 24 1110.9DES, F13A1, PTGDS, MUC1, ACTC1
44paraffin447.8DES, IGF2, F13A1, VIM, MUC1, ACTC1
45progesterone44 28 61 24 1111.8DES, IGF2, F13A1, VIM, MUC1, ACTC1
46vegf447.8DES, IGF2, F13A1, VIM, MUC1, ACTC1
47creatinine447.7DES, IGF2, PTGDS, VIM, MUC1, ACTC1
48testosterone44 61 24 1110.7DES, IGF2, PTGDS, VIM, MUC1, ACTC1
49retinoic acid44 248.7DES, IGF2, PTGDS, VIM, MUC1, ACTC1
50estrogen447.2DES, IGF2, F13A1, PTGDS, VIM, MUC1

GO Terms for genes affiliated with Hemangiopericytoma

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Cellular components related to Hemangiopericytoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:0058829.6VIM, DES
2platelet alpha granule lumenGO:0310939.2F13A1, IGF2

Biological processes related to Hemangiopericytoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to ethanolGO:0454719.2ACTC1, IGF2
2platelet degranulationGO:0025769.2F13A1, IGF2
3muscle filament slidingGO:0300498.7ACTC1, VIM, DES

Molecular functions related to Hemangiopericytoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of cytoskeletonGO:0052009.6VIM, DES

Products for genes affiliated with Hemangiopericytoma

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Sources for Hemangiopericytoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet