MCID: HMN013
MIFTS: 58

Hemangiopericytoma malady

Summaries for Hemangiopericytoma

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8Disease Ontology, 42NIH Rare Diseases, 63Wikipedia, 32MalaCards
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NIH Rare Diseases:42 Hemangiopericytoma is a term used to described a group of tumors that are derived from pericytes, the cells normally arranged along specific types of blood vessels called capillaries and venules. these types of tumors are typically slow-growing, may be either benign (non-cancerous) or malignant (cancerous), and may occur anywhere in the body. last updated: 11/19/2013

MalaCards: Hemangiopericytoma, also known as hemangiopericytoma, malignant, is related to meningioma and sarcoma. An important gene associated with Hemangiopericytoma is DES (desmin), and among its related pathways are Striated Muscle Contraction and EGFR Signaling Pathway. The compounds estrogen and glycogen have been mentioned in the context of this disorder. Affiliated tissues include bone, lung and breast, and related mouse phenotypes are reproductive system and embryogenesis.

Disease Ontology:8 A soft tissue cancer that is a soft tissue sarcoma and originates in the pericytes in the walls of capillaries.

Wikipedia:63 A hemangeopericytoma (HPC) is a type of soft tissue sarcoma that originates in the pericytes in the... more...

Aliases & Classifications for Hemangiopericytoma

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8Disease Ontology, 42NIH Rare Diseases, 10DISEASES, 44Novoseek, 60UMLS, 56SNOMED-CT, 34MeSH, 39NCIt
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Aliases & Descriptions:

hemangiopericytoma 8 42 10 44 60
hemangiopericytoma, malignant 8 60
haemangiopericytic meningioma 8
malignant hemangiopericytoma 8


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Disease Ontology8 DOID:264
MeSH34 D006393
SNOMED-CT56 134335004, 36060005
NCIt39 C3087

Related Diseases for Hemangiopericytoma

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17GeneCards, 18GeneDecks
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Diseases in the Hemangiopericytoma family:

Adult Malignant Hemangiopericytoma

Diseases related to Hemangiopericytoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 229)
idRelated DiseaseScoreTop Affiliating Genes
1meningioma30.5PTGDS, EPB41L3, CD34, MUC1, IGF2, NF2
2sarcoma30.4ACTC1, CD34, MUC1, IGF2, NF2, SSX2
3glomus tumor30.3ACTC1, DES, S100A1, VIM
4synovial sarcoma30.2CDH1, MUC1, IGF2, SSX2, DES, MDM2
5pituitary adenoma30.1RB1, MGMT, E2F1
6liposarcoma30.1CD34, DES, RB1, MDM2, VIM
7adenoma30.1ACTC1, CDH1, MUC1, IGF2, RB1, MGMT
8hemangioblastoma30.0MUC1, S100B
9fibrous meningioma30.0MUC1, NF2, S100B
10endometrial stromal sarcoma30.0ACTC1, DES, VIM
11angiosarcoma30.0ACTC1, CD34, MUC1, VIM
12benign meningioma30.0EPB41L3, NF2, MDM2
13fibrous histiocytoma30.0ACTC1, CD34, DES, F13A1, S100B, VIM
14seminoma29.7IGF2, SSX2
15mesenchymal chondrosarcoma29.7MUC1, DES, VIM
16lipoma29.7CD34, DES, MDM2, S100A1
17neurofibromatosis29.7NGFR, NF2, S100B
18retinoblastoma29.7NGFR, RB1, MDM2, E2F1
19smooth muscle tumor29.7ACTC1, IGF2, DES, S100A1, S100B, VIM
20giant cell tumor29.7ACTC1, MUC1, DES, F13A1, S100B, VIM
21papillary carcinoma29.7ACTC1, CDH1, MUC1, E2F1, S100A1
22leiomyoma29.7ACTC1, CD34, IGF2, DES, S100A1, S100B
23chondrosarcoma29.7MUC1, DES, MDM2, E2F1, S100A1, S100B
24gastrointestinal stromal tumor29.7ACTC1, CD34, NF2, DES, E2F1, S100A1
25neurofibroma29.7ACTC1, CD34, MUC1, NGFR, NF2, F13A1
26transitional cell carcinoma29.7CDH1, RB1, MDM2
27meninges hemangiopericytoma10.7
28meningitis10.7
29hypoglycemia10.5
30retroperitoneal hemangiopericytoma10.4
31breast hemangiopericytoma10.4
32kidney hemangiopericytoma10.4
33osteomalacia10.3
34mediastinitis10.3
35hepatitis10.3
36heart malignant hemangiopericytoma10.2
37malignant mediastinum hemangiopericytoma10.2
38conventional malignant hemangiopericytoma10.2
39childhood malignant hemangiopericytoma10.1
40adult intracranial malignant hemangiopericytoma10.1
41hepatitis a10.1
42adult malignant hemangiopericytoma10.1
43cervicitis10.1
44histiocytoma10.1
45pancreatitis10.1
46peritonitis10.1
47intracranial embolism10.0
48trigonitis10.0
49arteriovenous malformation10.0
50cerebritis10.0

Graphical network of the top 20 diseases related to Hemangiopericytoma:



Diseases related to hemangiopericytoma

Clinical Features for Hemangiopericytoma

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Drugs & Therapeutics for Hemangiopericytoma

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Hemangiopericytoma

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Anatomical Context for Hemangiopericytoma

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32MalaCards
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MalaCards organs/tissues related to Hemangiopericytoma:

32
Bone, Lung, Breast, Liver, Tongue, Pituitary, Kidney, Ovary, Pineal, Heart, Uterus, Spleen, Spinal cord, Adipocyte, Skin, Trachea, Testis, Prostate, Small intestine, Brain, Adrenal gland, Salivary gland, Smooth muscle, Colon, Eye

Animal Models for Hemangiopericytoma or affiliated genes

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36MGI
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Publications for Hemangiopericytoma

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50PubMed
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Articles related to Hemangiopericytoma:

(show top 50)    (show all 532)
idTitleAuthorsYear
1
Misinterpretation of statistical results and recurrent intracranial hemangiopericytoma. (24185443)
2014
2
Hemangiopericytoma: Radical resection remains the cornerstone of therapy. (24231562)
2013
3
Malignant fat-forming solitary fibrous tumor (lipomatous hemangiopericytoma) in the neck: Imaging and histopathological findings of a case. (23705040)
2013
4
Solitary fibrous tumors and so-called hemangiopericytoma. (22566753)
2012
5
Meningeal Hemangiopericytoma with Intracranial Metastases in an HIV-Positive Male: Case Report and Review of the Literature. (22666206)
2012
6
Thirty-nine cases of intracranial hemangiopericytoma and anaplastic hemangiopericytoma: a retrospective review of MRI features and pathological findings. (22658867)
2012
7
An infantile splenic hemangiopericytoma case treated with partial splenectomy. (22417056)
2012
8
Hemangiopericytoma in the trigone of the lateral ventricle. (21613766)
2011
9
Hemangiopericytoma/Solitary fibrous tumor of the oral cavity. (21378362)
2011
10
Retroperitoneal hemangiopericytoma: case report and literature review. (21362325)
2011
11
Hemangiopericytoma of the adult male breast. (22057611)
2011
12
Preoperative radiation therapy in the management of recurrent orbital hemangiopericytoma. (21242853)
2011
13
Skull base hemangiopericytoma: treatment options. (20169789)
2010
14
Acute abdomen due to rupture of hemangiopericytoma of the greater omentum: case report. (20037881)
2009
15
Mediastinal hemangiopericytoma. (19365827)
2009
16
Hemangiopericytoma: an unusual cause of peritoneal carcinomatosis. (19602469)
2009
17
Malignant hemangiopericytoma of the breast: a case report with a review of the literature. (18253740)
2008
18
Contrast-enhanced ultrasonography of hepatic metastasis of hemangiopericytoma. (18359915)
2008
19
Hemangiopericytoma of the parotid gland: a case report. (17527065)
2007
20
A case of congenital maxillary hemangiopericytoma: a case report. (17307606)
2007
21
Clinical and pathological characteristics of primary intraspinal hemangiopericytoma and choice of treatment. (17335652)
2007
22
Metastatic hemangiopericytoma of the skin treated with wide local excision and MGN-3. (16393616)
2006
23
Recurrent superior mediastinal primary hemangiopericytoma 23 years after the complete initial excision: a case report. (16838049)
2006
24
Hepatic metastases of hemangiopericytoma: contrast-enhanced MRI, contrast-enhanced ultrasonography and angiography findings. (16766270)
2006
25
Stent-graft repair of an aortic rupture caused by invasive hemangiopericytoma. (16731179)
2006
26
Bilateral metastatic renal hemangiopericytoma ten years after primary intracranial lesion. (16813674)
2006
27
Case of cutaneous metastasis from intracranial hemangiopericytoma. (16207194)
2005
28
F-18 FDG positron emission tomography imaging of rare soft tissue sarcomas: low-grade fibromyxoid sarcoma and malignant hemangiopericytoma. (15311133)
2004
29
Sinonasal-type hemangiopericytoma: a clinicopathologic and immunophenotypic analysis of 104 cases showing perivascular myoid differentiation. (12766577)
2003
30
Hemangiopericytoma of mesentery: a case report. (15027729)
2003
31
Cutaneous malignant hemangiopericytoma with unusual clinical behavior. (12081167)
2002
32
Hemangiopericytoma of the parotid gland: CT and MR features. (11419156)
2001
33
Tc-99m MDP and Tl-201 scintigraphy in a case of metastatic meningeal hemangiopericytoma. (11711721)
2001
34
Pelvic hemangiopericytoma in a patient with mixed germ cell tumor of the testis. (11586234)
2001
35
Malignant hemangiopericytoma of the head and neck: a report of 3 cases. (11243622)
2001
36
Hemangiopericytoma of the buccal region: a case report. (11289179)
2001
37
Malignant hemangiopericytoma of the bone. (10857492)
2000
38
Hemangiopericytoma ischiorectal. Report of a case. (9833715)
1998
39
Immunohistochemical detection of vascular growth factors in angiomatous and atypical meningiomas, as well as hemangiopericytomas. (9342757)
1997
40
Endoscopic resection of a recurrent sinonasal hemangiopericytoma. (9282253)
1997
41
Hemangiopericytoma of the chest wall. (9033336)
1997
42
Primary hemangiopericytoma of bone located in the tibia. (9040143)
1997
43
Primary pulmonary malignant hemangiopericytoma associated with coagulopathy. (9307488)
1997
44
Hemangiopericytoma: a rare pineal mass. (8957805)
1996
45
Sinonasal hemangiopericytomas: a clinicopathologic and immunohistochemical study of seven cases. (8774921)
1996
46
Insulin-like growth factor II expression in primary meningeal hemangiopericytoma and its metastasis to the liver accompanied by hypoglycemia. (8760024)
1996
47
Hemangiopericytoma: a report of two cases arising on the lip. (8909742)
1996
48
Malignant "triton" tumor with metastatic hemangiopericytoma in a patient associated with von Recklinghausen's disease. (3087135)
1986
49
Retroperitoneal hemangiopericytoma. (1113722)
1975
50
Retroperitoneal hemangiopericytoma associated with hypoglycemia and masculinization. (13630072)
1959

Genetic Variations for Hemangiopericytoma

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Expression for genes affiliated with Hemangiopericytoma

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hemangiopericytoma

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Pathways for genes affiliated with Hemangiopericytoma

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37NCBI BioSystems Database, 53Reactome, 55SinoBiological, 12EMD Millipore, 29KEGG, 51QIAGEN, 4Cell Signaling Technology
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Compounds for genes affiliated with Hemangiopericytoma

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44Novoseek, 24HMDB, 49PharmGKB, 59Tocris Bioscience, 11DrugBank, 28IUPHAR, 2BitterDB
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Compounds related to Hemangiopericytoma according to GeneCards/GeneDecks:

(show top 50)    (show all 114)
idCompoundScoreTop Affiliating Genes
1estrogen4410.8F13A1
2glycogen44 2411.6IGF2, ACTC1, MDM2
3reticulin4410.6VIM, DES, MUC1, ACTC1
4orcein4410.5VIM, ACTC1, S100B, DES
5creatinine4410.4ACTC1, CDH1, IGF2, PTGDS
62-methoxyethanol4410.4S100A1, VIM, IGF2, ACTC1
7s 1004410.3VIM, F13A1, DES, MUC1, ACTC1, S100B
8mucicarmine4410.3S100B, VIM, DES, MUC1, S100A1, ACTC1
9etoposide44 49 59 1113.2S100B, VIM, RB1, IGF2, CDH1, MDM2
10biotin44 11 2412.2ACTC1, MUC1, DES, RB1, VIM, S100A1
11progestin4410.2VIM, DES, CDH1, MUC1, IGF2
12dexamethasone44 49 28 1113.2MGMT, S100B, CDH1, IGF2, RB1, MDM2
13serine4410.2S100B, NF2, CDH1, DES, E2F1
14p0024410.2CDH1, MGMT, MDM2, RB1, IGF2, DES
15silver4410.2S100A1, PTGDS, F13A1, CDH1, DES, CD34
16paclitaxel44 49 1112.2MDM2, S100B, CDH1, IGF2, E2F1, RB1
17adriamycin4410.1VIM, E2F1, MDM2, RB1, DES, MUC1
18thymidylate4410.1MDM2, MGMT, E2F1, RB1, VIM, CDH1
19b 7234410.1MUC1, CDH1, ACTC1, DES, VIM, S100B
20formaldehyde44 2411.1MUC1, ACTC1, VIM, S100B, MGMT, RB1
215-aza-2deoxycytidine4410.0SSX2, MGMT, CDH1, MDM2, EPB41L3, IGF2
22azathioprine44 49 2 1113.0VIM, DES, IGF2, MGMT, CDH1
23methotrexate44 49 1112.0MUC1, RB1, MDM2, MGMT, VIM, CDH1
245fluorouracil4410.0RB1, CDH1, MGMT, MDM2, E2F1, IGF2
25chloramphenicol44 2 1112.0MUC1, MGMT, VIM, S100B, E2F1, IGF2
26vincristine44 49 1112.0RB1, MGMT, E2F1, VIM
27actinomycin d4410.0RB1, DES, IGF2, MUC1, E2F1, VIM
28estradiol44 11 2412.0MDM2, RB1, DES, IGF2, MUC1, E2F1
29rapamycin4410.0MDM2, E2F1, NF2, IGF2, CDH1, VIM
30steroid4410.0ACTC1, DES, NGFR, MDM2, RB1, E2F1
31doxorubicin44 49 1112.0MGMT, VIM, CDH1, E2F1, DES, RB1
3212-o-tetradecanoylphorbol 13-acetate449.9CD34, CDH1, MUC1, NGFR, DES, RB1
33calcium44 49 11 2412.9ACTC1, S100B, MUC1, NGFR, DES, F13A1
34cyclic amp44 2410.9RB1, VIM, CDH1, MUC1, NGFR, DES
35matrigel449.9ACTC1, CDH1, MUC1, NGFR, RB1, VIM
36hematoxylin449.9VIM, S100B, S100A1, F13A1, DES, NGFR
37iron44 2410.9F13A1, S100A1, DES, ACTC1, MDM2, S100B
38oligonucleotide449.8VIM, MGMT, E2F1, MDM2, RB1, F13A1
39agar449.8VIM, MDM2, RB1, NF2, IGF2, NGFR
40nitric oxide44 11 2411.8MGMT, NGFR, E2F1, MDM2, MUC1, DES
41testosterone44 59 11 2412.7MUC1, ACTC1, VIM, PTGDS, S100B, RB1
42crcs449.7MUC1, RB1, MGMT, CDH1
43thymidine44 2410.7MGMT, EPB41L3, DES, NGFR, RB1, MDM2
44cysteine449.6MDM2, NF2, IGF2, VIM, NGFR, MUC1
45cisplatin44 49 59 1112.6RB1, MDM2, MGMT, E2F1, MUC1, IGF2
46tyrosine449.4DES, RB1, E2F1, S100A1, MDM2, NF2
47vegf449.4IGF2, DES, F13A1, RB1, MDM2, MGMT
48retinoic acid44 2410.4VIM, MUC1, CDH1, S100B, S100A1, E2F1
49paraffin449.3MGMT, MDM2, RB1, F13A1, DES, NF2
50progesterone44 59 28 11 2413.0MDM2, MGMT, E2F1, S100A1, S100B, VIM

GO Terms for genes affiliated with Hemangiopericytoma

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16Gene Ontology
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Cellular components related to Hemangiopericytoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1Rb-E2F complexGO:0351899.9RB1, E2F1
2perinuclear region of cytoplasmGO:0484719.9PTGDS, CD34, CDH1, NF2, S100B

Biological processes related to Hemangiopericytoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of transcription involved in G1/S transition of mitotic cell cycleGO:07193010.3RB1, E2F1
2regulation of cysteine-type endopeptidase activity involved in apoptotic processGO:04328110.3CDH1, NGFR, MGMT
3negative regulation of cell-cell adhesionGO:02240810.2CDH1, NF2
4muscle filament slidingGO:03004910.2ACTC1, DES, VIM
5cellular response to hypoxiaGO:07145610.0S100B, E2F1, MDM2
6response to drugGO:0424939.7ACTC1, CDH1, MDM2, MGMT

Molecular functions related to Hemangiopericytoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of cytoskeletonGO:00520010.2EPB41L3, DES, VIM
2S100 protein bindingGO:0445489.9S100A1, S100B
3identical protein bindingGO:0428029.8DES, RB1, MDM2, S100A1, S100B, VIM
4protein bindingGO:0055158.9MDM2, E2F1, S100A1, S100B, VIM, RB1

Products for genes affiliated with Hemangiopericytoma

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Sources for Hemangiopericytoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet