Hemangiopericytoma malady

NIH Rare Diseases: Hemangiopericytoma is a term used to described a group of tumors that are derived from pericytes, the cells normally arranged along specific types of blood vessels called capillaries and venules.  These types of tumors are typically slow-growing, may be either benign (non-cancerous) or malignant (cancerous), and may occur anywhere in the body. ³⁰

MalaCards: Hemangiopericytoma, also known as hemangiopericytoma, malignant (morphologic abnormality), is related to meninges hemangiopericytoma and fibrous meningioma. An important gene associated with Hemangiopericytoma is DES (desmin), and among its related pathways are Glioblastoma Multiforme and eNOS Signaling. The compounds glucose and mucicarmine have been mentioned in the context of this disorder. Affiliated tissues include heart and liver, and related mouse phenotypes are endocrine/exocrine gland and respiratory system.

Disease Ontology: A soft tissue cancer that is a soft tissue sarcoma and originates in the pericytes in the walls of capillaries.⁶

Wikipedia: A hemangeopericytoma (HPC) is a type of soft tissue sarcoma that originates in the pericytes in the...⁴⁴ more...

Aliases & Descriptions:

hemangiopericytoma 6 30 8 32 43 hemangiopericytoma, malignant (morphologic abnormality) 6 haemangiopericytic meningioma 6

hemangiopericytoma (disorder) 6 hemangiopericytoma, malignant 43 malignant hemangiopericytoma 6

Diseases related to hemangiopericytoma by text searches and GeneDecks gene sharing:

(show top 50)    (show all 603)

id	Related Disease	Score	Top Affiliating Genes
1	meninges hemangiopericytoma	32.1	NCAM1, RB1, VIM, MUC1, CDH1, IGF2
2	fibrous meningioma	29.7	MUC1, S100B, NF2, DES
3	meningitis	28.8	NCAM1, RB1, VIM, VEGFA, MUC1, S100B
4	glomus tumor	27.6	VIM, MUC1, S100A1, S100B, CD34, F8
5	hypoglycemia	27.5	VIM, VEGFA, FGF2, IGF1R, IGF2, IGFBP3
6	liposarcoma	26.0	RB1, VIM, VEGFA, KDR, MUC1, CD34
7	anaplastic meningioma	26.0	RB1, VIM, VEGFA, KDR, MUC1, S100A1
8	hemangioblastoma	25.5	NCAM1, VIM, VEGFA, KDR, MUC1, S100A1
9	hemangioendothelioma	25.4	VEGFA, KDR, S100B, CD34, FLT4, FGF2
10	angiosarcoma	24.4	VIM, VEGFA, KDR, MUC1, S100B, CD34
11	meningioma	23.7	NCAM1, RB1, VIM, VEGFA, KDR, MUC1
12	retinoblastoma	22.3	NCAM1, RB1, VIM, VEGFA, MUC1, S100B
13	cerebritis	18.5	NCAM1, VIM, VEGFA, KDR, S100B, CEACAM3
14	lymph node palisaded myofibroblastoma	13.8	VIM, DES
15	myxosarcoma	13.8	VIM, DES
16	infantile digital fibromatosis	13.8	VIM, DES
17	prostate leiomyoma	13.8	VIM, DES
18	clear cell ependymoma	13.8	VIM, MUC1
19	spindle cell thymoma	13.8	MUC1, DES
20	prostate stromal sarcoma	13.8	VIM, MUC1
21	mesenchymal chondrosarcoma	13.8	VIM, MUC1, DES
22	glomangiomyoma	13.8	VIM, ACTC1, DES
23	infantile myofibromatosis	13.8	VIM, ACTC1, DES
24	adenoid squamous cell carcinoma	13.8	VIM, MUC1, CD34
25	metanephric adenoma	13.8	VIM, MUC1, DES
26	pseudosarcomatous fibromatosis	13.8	VIM, ACTC1, DES
27	epithelioid leiomyosarcoma	13.8	VIM, ACTC1, DES
28	glomangioma	13.8	S100A1, ACTC1, DES
29	benign metastasizing leiomyoma	13.7	VIM, ACTC1, DES
30	breast metaplastic carcinoma	13.7	VIM, S100A1, DES
31	epithelioid sarcoma	13.7	VIM, MUC1, CD34
32	malignant fibroxanthoma	13.7	VIM, CD34, DES
33	endometrial stromal sarcoma	13.7	VIM, ACTC1, DES
34	orbit rhabdomyosarcoma	13.7	VIM, MDM2, DES
35	congenital epulis	13.7	VIM, S100B, DES
36	multicystic renal dysplasia, bilateral	13.7	VIM, IGF2, ACTC1
37	hepatic angiomyolipoma	13.7	RB1, VIM, DES
38	secretory meningioma	13.7	VIM, MUC1, NF2
39	malignant giant cell tumor of soft parts	13.7	S100B, ACTC1, DES
40	meninges sarcoma	13.7	VIM, DES
41	rectum sarcomatoid carcinoma	13.7	VIM, MUC1, ACTC1, DES
42	endometrial mucinous adenocarcinoma	13.7	VIM, MUC1
43	congenital mesoblastic nephroma	13.7	VIM, MDM2, IGF2
44	clear cell meningioma	13.7	VIM, MUC1
45	cystic nephroma	13.7	VIM, MUC1, ACTC1, DES
46	myoma	13.7	MDM2, ACTC1, DES
47	pleomorphic carcinoma	13.7	VIM, MUC1, DES
48	transitional meningioma	13.7	NCAM1, MUC1, NF2
49	cutaneous fibrous histiocytoma	13.7	VIM, CD34, F13A1, DES
50	langerhans-cell histiocytosis	13.7	S100A1, S100B, F13A1

Approved drugs:

Drug clinical trials:

MalaCards organs/tissues related to hemangiopericytoma:

²²

MGI Mouse Phenotypes related to hemangiopericytoma:

²⁵ (show all 24)

id	Description	MGI Source Accession	Score	Top Affiliating Genes
1	endocrine/exocrine gland phenotype	MP:0005379	10.2	NF2, EPB41L3
2	respiratory system phenotype	MP:0005388	10.1	PGF, TIE1, NF2, F13A1
3	liver/biliary system phenotype	MP:0005370	9.9	VEGFA, NGFR, NF2
4	embryogenesis phenotype	MP:0005380	9.8	TIE1, NF2, MDM2, FLT4, VIM
5	hematopoietic system phenotype	MP:0005397	9.5	E2F1, F13A1, IGF2, MDM2, FGF2, CD34
6	nervous system phenotype	MP:0003631	9.1	E2F1, THBD, TIE1, NF2, IGF2, MDM2
7	no phenotypic analysis	MP:0003012	8.5	SST, IGF2, FLT4, CDH1, MUC1, VEGFA
8	integument phenotype	MP:0010771	8.4	NGFR, HBA2, TIE1, TGFA, E2F1, PTGDS
9	reproductive system phenotype	MP:0005389	8.3	EPB41L3, E2F1, HBA1, NF2, F8, FGF2
10	hearing/vestibular/ear phenotype	MP:0005377	8.0	E2F1, ACTG1, NF2, NGFR, IGF1, IGF1R
11	adipose tissue phenotype	MP:0005375	8.0	E2F1, PGF, TGFA, IGF1, IGFBP3, IGF1R
12	immune system phenotype	MP:0005387	7.8	NF2, GFAP, TIE1, PGF, E2F1, PTGDS
13	tumorigenesis	MP:0002006	7.6	EPB41L3, E2F1, PGF, NF2, PTGDS, IGF1
14	behavior/neurological phenotype	MP:0005386	7.5	SST, NGFR, ACTG1, GFAP, DES, E2F1
15	vision/eye phenotype	MP:0005391	7.4	NGFR, NF2, GFAP, TGFA, PGF, E2F1
16	digestive/alimentary phenotype	MP:0005381	7.0	NGFR, ACTG1, GFAP, TIE1, THBD, TGFA
17	growth/size phenotype	MP:0005378	7.0	ACTG1, HBA2, GFAP, TIE1, THBD, TGFA
18	normal phenotype	MP:0002873	7.0	EPB41L3, E2F1, THBD, GFAP, SST, IGF1
19	skeleton phenotype	MP:0005390	6.5	E2F1, TGFA, NF2, IGF1, IGF2, IGF1R
20	mortality/aging	MP:0010768	6.4	ACTG1, HBA1, HBA2, GFAP, TIE1, THBD
21	cellular phenotype	MP:0005384	5.6	IGF1, NGFR, ACTC1, HBA2, GFAP, TIE1
22	muscle phenotype	MP:0005369	5.4	RB1, NGFR, ACTC1, ACTG1, HBA2, GFAP
23	cardiovascular system phenotype	MP:0005385	5.2	F13A1, NGFR, ACTC1, GFAP, TIE1, THBD
24	homeostasis/metabolism phenotype	MP:0005376	3.8	ACTC1, NF2, NGFR, SST, F13A1, HBA2

Articles related to hemangiopericytoma:

(show all 33)

id	Title	Authors	Year	Affiliating Genes
1	Inhibiting the VEGF-VEGFR pathway in angiosarcoma, ep ithelioid hemangioendothelioma, and hemangiopericytoma/solitary fibrous tumor. (20485168)	Park M.S.... Araujo D.M.	2010	KDR, VEGFA
2	Hemangiopericytoma-associated hypoglycemia improved b y glucocorticoid therapy: a case report. (19387873)	AnaforoA9lu I.... AlgA1n E.	2009	IGF1, IGF2
3	Retinoblastoma (Rb) tumor-suppressor pathway alterations in meningeal hemangiopericytomas: High E2F transcription factor 1 expression and loss of Rb expression: study by double immunofluorescence staining and laser-scanning confocal microscopy. (18459177)	Martinez J.C.... Ricoy J.R.	2008	RB1, E2F1
4	Rare case of hemangiopericytoma responds to sunitinib . (18279811)	Mulamalla K.... Dudek A.Z.	2008	KDR
5	Prenatal diagnosis of a giant congenital primary cerebral hemangiopericytoma. (16554916)	Sobel G.... BA!nhidy F.	2006	CD34
6	Sinonasal hemangiopericytoma-like tumor with true pericytic myoid differentiation: a clinicopathologic and immunohistochemical study of five cases. (15529319)	Kuo F.Y.... Huang C.C.	2005	ACTC1
7	Multiple extracranial metastases from a meningeal hemangiopericytoma and severe hypoglycemia: a case report (15227844)	Miyamoto S.... Itabashi M.	2004	IGF2
8	Anaplastic meningioma versus meningeal hemangiopericytoma: immunohistochemical and genetic markers. (15668900)	Rajaram V.... Perry A.	2004	NF2, EPB41L3
9	Hypoglycemia associated with the production of insul in-like growth factor (IGF)-II by a hemangiopericytoma (12571793)	Plikat K.... SchAPlmerich J.	2003	IGF2
10	Case of primary malignant hemangiopericytoma of the heart expressing basement membrane-degradable enzymes. (12366815)	Okada Y.... Sasaki S.	2002	MMP3, F13A1, S100A1
11	Primary epidural hemangiopericytoma in the lumbar spine: a case report. (11923676)	Ijiri K.... Komiya S.	2002	THBD
12	Orbital hemangiopericytoma and solitary fibrous tumor: a morphologic continuum. (12574845)	Goldsmith J.D.... Syed N.	2001	CD34, F13A1
13	Prostaglandin D synthase (beta-trace) in meningeal hemangiopericytoma. (11266526)	Kawashima M.... Iwaki T.	2001	PTGDS
14	Insulin-like growth factor II-producing intra-abdomin al hemangiopericytoma associated with hypoglycemia. (11777215)	Matsuda S.... Shiraishi T.	2001	IGF2
15	Clinicopathological features of solitary fibrous tumor of the meninges: An immunohistochemical reappraisal of cases previously diagnosed to be fibrous meningioma or hemangiopericytoma. (11107053)	Suzuki S.O.... Iwaki T.	2000	MUC1
16	Contribution of immunohistochemistry and electron microscopy for the diagnosis of meningeal hemangiopericytomas. 15 case reports (11084416)	Bouvier-Labit C.... Figarella-Branger D.	2000	CDH1, VIM, NCAM1
17	The expression and role of insulin-like growth factor II in malignant hemangiopericytomas. (10682323)	Pavelic K.... Pavelic J.	1999	IGF1R, IGF2
18	Lipomatous hemangiopericytoma: a rare variant of hema ngiopericytoma that may be confused with liposarcoma. (10524520)	Folpe A.L.... Weiss S.W.	1999	F13A1
19	Molecular pathology of hemangiopericytomas accompanied by severe hypoglycemia: oncogenes, tumor-suppressor genes and the insulin-like growth factor family. (9692837)	PaveliA8 K.... PaveliA8 J.	1998	IGF1R, IGF2
20	Intracranial hemangiopericytomas. Histological and immunohistochemical study. (9377077)	Kroh H.... Sobieraj A.	1997	MUC1
21	The immunophenotypic spectrum of meningeal hemangiopericytoma: a comparison with fibrous meningioma and solitary fibrous tumor of meninges. (9351573)	Perry A.... Nascimento A.G.	1997	DES
22	Immunohistochemical detection of vascular growth factors in angiomatous and atypical meningiomas, as well as hemangiopericytomas. (9342757)	Dietzmann K.... Firsching R.	1997	TGFA
23	Hemangiopericytoma of the liver: immunohistochemical observations, expression of angiogenic factors, and review of the literature. (9329468)	Flores-Stadler E.M.... Gonzalez-Crussi F.	1997	FGF2, VEGFA, F13A1
24	Tumor size-related DNA copy number changes occur in solitary fibrous tumors but not in hemangiopericytomas. (9436963)	Miettinen M.M.... Knuutila S.	1997	CD34
25	Vascular growth factors and receptors in capillary hemangioblastomas and hemangiopericytomas. (8774132)	Hatva E.... Alitalo K.	1996	FLT4, VEGFA, PGF
26	Mechanisms of tumor-induced hypoglycemia with intraabdominal hemangiopericytoma. (8772551)	Chung J.... Henry R.R.	1996	IGF2, SST
27	Sinonasal hemangiopericytomas: a clinicopathologic and immunohistochemical study of seven cases. (8774921)	Catalano P.J.... Biller H.F.	1996	VIM, F13A1
28	Insulin-like growth factor II expression in primary meningeal hemangiopericytoma and its metastasis to the liver accompanied by hypoglycemia. (8760024)	Sohda T.... Yun K.	1996	IGF2, IGFBP3
29	A comparative study of 'angioblastic meningioma', hemangiopericytoma and cerebellar hemangioblastoma (8340101)	Zhou Q.... Yang X.	1993	VIM, GFAP
30	The immunophenotype of hemangiopericytomas and glomus tumors, with special reference to muscle protein expression: an immunohistochemical study and review of the literature. (1708501)	Porter P.L.... Gown A.M.	1991	VIM, DES, NGFR
31	Imaging of a parapharyngeal hemangiopericytoma. Radioimmunoscintigraphy (SPECT) with indium-111-labeled anti-CEA antibody, and comparison to digital subtraction angiography, computed tomography, and immunohistochemistry. (1985724)	Kairemo K.J.... HeikkilAo P.S.	1991	CEACAM3
32	Intermediate filament proteins and actin isoforms as markers for soft-tissue tumor differentiation and origin. III. Hemangiopericytomas and glomus tumors. (2158236)	SchA1rch W.... Gabbiani G.	1990	VIM, DES, ACTG1
33	Soft-tissue and meningeal hemangiopericytomas: an immunohistochemical and ultrastructural study. (2318483)	d'Amore E.S.... Sung J.H.	1990	VIM, DES, MUC1

Genes related to hemangiopericytoma according to GeneCards:

(show all 42)

id	Symbol	Description	Score	GeneCards Section Context
1	DES	desmin	11.0	Publications
2	IGF2	insulin-like growth factor 2 (somatomedin A)	11.0	Publications
3	VIM	vimentin	11.0	Publications
4	MUC1	mucin 1, cell surface associated	11.0	Publications
5	MIR4273	microRNA 4273	11.0
6	PTGDS	prostaglandin D2 synthase 21kDa (brain)	11.0	Publications
7	CD34	CD34 molecule	11.0	Publications
8	S100A1	S100 calcium binding protein A1	11.0	Publications
9	NF2	neurofibromin 2 (merlin)	11.0	Publications
10	NGFR	nerve growth factor receptor	11.0	Publications
11	F13A1	coagulation factor XIII, A1 polypeptide	11.0	Publications
12	EPB41L3	erythrocyte membrane protein band 4.1-like 3	11.0	Publications
13	ACTC1	actin, alpha, cardiac muscle 1	11.0	Publications
14	E2F1	E2F transcription factor 1	11.0	Publications
15	NCAM1	neural cell adhesion molecule 1	11.0	Publications
16	IGFBP3	insulin-like growth factor binding protein 3	11.0	Publications
17	RB1	retinoblastoma 1	11.0	Publications
18	MDM2	Mdm2, p53 E3 ubiquitin protein ligase homolog (mouse)	11.0
19	S100B	S100 calcium binding protein B	11.0
20	CDH1	cadherin 1, type 1, E-cadherin (epithelial)	11.0	Publications
21	SSX2	synovial sarcoma, X breakpoint 2	11.0
22	TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	11.0	Publications
23	PGF	placental growth factor	11.0	Publications
24	UBE2D1	ubiquitin-conjugating enzyme E2D 1	11.0
25	ACTG1	actin, gamma 1	11.0	Publications
26	HBA2	hemoglobin, alpha 2	11.0
27	CEACAM3	carcinoembryonic antigen-related cell adhesion molecule 3	11.0	Publications
28	FLT4	fms-related tyrosine kinase 4	11.0	Publications
29	HBA1	hemoglobin, alpha 1	11.0
30	CALD1	caldesmon 1	11.0
31	THBD	thrombomodulin	11.0	Publications
32	CNTN3	contactin 3 (plasmacytoma associated)	11.0
33	GFAP	glial fibrillary acidic protein	11.0	Publications
34	MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	11.0	Publications
35	TGFA	transforming growth factor, alpha	11.0	Publications
36	SST	somatostatin	11.0	Publications
37	IGF1R	insulin-like growth factor 1 receptor	11.0	Publications
38	KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	11.0	Publications
39	FGF2	fibroblast growth factor 2 (basic)	11.0	Publications
40	F8	coagulation factor VIII, procoagulant component	11.0
41	IGF1	insulin-like growth factor 1 (somatomedin C)	11.0	Publications
42	VEGFA	vascular endothelial growth factor A	11.0	Publications

Pathways related to hemangiopericytoma according to GeneDecks:

(show top 50)    (show all 82)

id	Pathway	Score	Top Affiliating Genes
1	Glioblastoma Multiforme36	9.8	MDM2, IGF1R, IGF2, RB1, NF2, E2F1
2	eNOS Signaling36	9.8	IGF2, TGFA, PGF, FLT4, ACTG1
3	Focal adhesion20	9.7	KDR, ACTG1
4	Transcription P53 signaling pathway10	9.7	VEGFA
5	Akt Signaling36	9.6	IGF1R, MDM2, NGFR, PGF, FLT4
6	Actin-Based Motility by Rho Family GTPases36	9.6	ACTG1, NGFR, IGF1, PGF
7	Bladder cancer20	9.6	E2F1, RB1, VEGFA, CDH1, MDM2, PGF
8	ERK5 Signaling36	9.5	FLT4, IGF2, PGF, TGFA, NGFR, KDR
9	Breast Cancer Regulation by Stathmin136	9.3	E2F1, TGFA, IGF1R, FGF2, NGFR
10	JNK Pathway36	9.2	FLT4, FGF2, NGFR, PGF, KDR
11	Transcription_P53 signaling pathway41	9.1	MDM2, E2F1, RB1, KDR, VEGFA
12	Glioma20	8.8	TGFA, RB1, IGF1R, IGF1, MDM2, E2F1
13	14-3-3 Induced Intracellular Signaling36	8.7	IGF1, PGF, FGF2, IGF1R, FLT4
14	Prostate cancer20	8.6	TGFA, MDM2, IGF1R, IGF1, E2F1, RB1
15	PTEN Pathway36	8.6	KDR, PGF, FLT4, ACTG1, NGFR, IGF1R
16	Melanoma20	8.5	RB1, CDH1, MDM2, IGF1R, FGF2, IGF1
17	PPAR Pathway36	8.5	IGF2, FGF2, IGF1R, IGF1, NGFR, PGF
18	CREB Pathway36	8.5	PGF, KDR, NGFR, IGF1, IGF2, IGF1R
19	Pathways in cancer20	8.5	E2F1, IGF1R, TGFA, MDM2, FGF2, VEGFA
20	Molecular Mechanisms of Cancer36	8.4	TGFA, FGF2, IGF2, RB1, IGF1R, MDM2
21	Ras Pathway36	8.4	FLT4, TGFA, ACTG1, IGF2, KDR, PGF
22	eIF2 Pathway36	8.3	FGF2, TGFA, IGF1, IGF2, IGF1R, FLT4
23	Rac1 Pathway36	8.1	PGF, NGFR, IGF1, IGF1R, FGF2, FLT4
24	Paxillin Interactions36	8.1	PGF, TGFA, ACTG1, FGF2, KDR, FLT4
25	NF-KappaB (p50-p65) Pathway36	8.0	PGF, NGFR, IGF2, FGF2, FLT4, KDR
26	NF-KappaB Family Pathway36	8.0	IGF2, KDR, FLT4, IGF1, TGFA, PGF
27	IP3 Pathway36	7.9	IGF1, FGF2, FLT4, PGF, TGFA, NGFR
28	TGF-Beta Pathway36	7.9	NGFR, IGF2, PGF, TGFA, IGF1, FLT4
29	Apoptotic Pathways in Synovial Fibroblasts36	7.7	PGF, TGFA, NGFR, IGF1, IGF2, KDR
30	DHA Signaling36	7.7	TGFA, FGF2, FLT4, KDR, IGF2, IGF1
31	Nanog in Mammalian ESC Pluripotency36	7.7	IGF2, PGF, TGFA, FLT4, KDR, FGF2
32	Nuclear Receptor Activation by Vitamin-A36	7.7	FGF2, FLT4, IGF1R, IGF2, IGF1, KDR
33	p70S6K Signaling36	7.7	IGF1, FLT4, KDR, PGF, IGF2, NGFR
34	Activation of PKC through GPCR36	7.7	TGFA, PGF, NGFR, IGF1, IGF2, IGF1R
35	Renin-Angiotensin Pathway36	7.7	IGF1R, FLT4, KDR, IGF2, IGF1, NGFR
36	Telomerase Components in Cell Signaling36	7.6	IGF1, RB1, KDR, FLT4, NGFR, PGF
37	p53 Mediated Apoptosis36	7.6	KDR, MDM2, IGF2, NGFR, FGF2, FLT4
38	Mitochondrial Apoptosis36	7.6	PGF, TGFA, NGFR, IGF1, IGF2, KDR
39	Cellular Apoptosis Pathway36	7.6	FGF2, MDM2, IGF1R, IGF2, IGF1, KDR
40	GSK3 Signaling36	7.5	PGF, TGFA, IGF1, IGF2, IGF1R, FGF2
41	NFAT in Immune Response36	7.5	IGF1, IGF1R, IGF2, TGFA, PGF, FLT4
42	PAK Pathway36	7.5	IGF1R, TGFA, ACTG1, FLT4, NGFR, KDR
43	JAK-STAT Pathway36	7.5	IGF2, PGF, IGF1, TGFA, IGF1R, KDR
44	Phospholipase-C Pathway36	7.4	TGFA, FGF2, KDR, IGF2, IGF1, FLT4
45	Estrogen Pathway36	7.4	KDR, FLT4, IGF1R, PGF, TGFA, IGF1
46	GPCR Pathway36	7.4	TGFA, PGF, IGF1, IGF2, FGF2, FLT4
47	ILK Signaling36	7.4	IGF2, VIM, ACTG1, IGF1, IGF1R, FGF2
48	Antioxidant Action of Vitamin-C36	7.4	KDR, FLT4, FGF2, IGF2, IGF1R, IGF1
49	Rho Family GTPases36	7.2	DES, PGF, FGF2, TGFA, GFAP, VIM
50	Pancreatic Adenocarcinoma36	7.1	RB1, IGF1R, KDR, FLT4, MMP3, FGF2

Compounds related to hemangiopericytoma according to GeneDecks:

(show top 50)    (show all 208)

id	Compound	Score	Top Affiliating Genes
1	glucose32	10.0	S100B, IGF2, ACTC1, TIE1, PGF, DES
2	mucicarmine32	9.9	S100A1, VIM, MUC1, S100B, CEACAM3, ACTC1
3	s 10032	9.9	DES, VIM, MUC1, S100B, F13A1, ACTC1
4	reticulin32	9.8	VIM, MUC1, S100B, DES, GFAP, ACTC1
5	b 72332	9.4	VIM, MUC1, S100A1, S100B, CEACAM3, CDH1
6	ly29400232	9.3	FGF2, CDH1, VEGFA
7	estradiol32 9 18 9	12.2	MUC1, DES, MDM2, F8, GFAP, VIM
8	etoposide32 42 9 9	12.0	CDH1, E2F1, IGF1R, MDM2, S100B, RB1
9	heparin32 9 18 9	11.9	VIM, NCAM1, DES, TGFA, F13A1, F8
10	hyaluronic acid32 18	9.7	VIM, MUC1, DES, MMP3, THBD, IGF1R
11	12-o-tetradecanoylphorbol 13-acetate32	8.7	RB1, E2F1, TGFA, CDH1, CD34, MMP3
12	hematoxylin32	8.7	GFAP, DES, ACTC1, NGFR, MMP3, CEACAM3
13	agar32	8.5	E2F1, TGFA, RB1, VIM, MUC1, CD34
14	adriamycin32	8.4	RB1, E2F1, DES, IGF1, IGF1R, MDM2
15	arginine32	8.4	DES, THBD, GFAP, SST, F8, MDM2
16	bromodeoxyuridine32	8.4	E2F1, TGFA, GFAP, FGF2, S100B, VIM
17	progesterone32 42 9 18 9	12.4	F8, NGFR, NF2, ACTC1, GFAP, DES
18	butyrate32	8.3	RB1, VIM, MUC1, CDH1, MMP3, IGF1R
19	glycogen32 18	9.3	CDH1, ACTC1, VIM, GFAP, THBD, DES
20	rapamycin32 42	9.1	MDM2, KDR, VEGFA, VIM, RB1, FLT4
21	progestin32	8.1	DES, TGFA, F8, IGF2, IGF1R, CDH1
22	gefitinib32 34 9 9	11.0	FGF2, VIM, CDH1, KDR, MDM2, IGF1R
23	dihydrotestosterone32 9 18 9	10.9	FGF2, IGF1R, IGFBP3, IGF1, TGFA, IGF2
24	cysteine32	7.9	GFAP, THBD, TGFA, MDM2, IGF1R, IGF2
25	tgf beta132	7.8	F8, VIM, KDR, CDH1, MMP3, IGF2
26	iron32 18	8.7	VIM, UBE2D1, MDM2, DES, GFAP, HBA2
27	5fluorouracil32	7.6	E2F1, RB1, VEGFA, KDR, MUC1, CEACAM3
28	doxorubicin32 34 9 9	10.4	VIM, VEGFA, KDR, CDH1, MDM2, NCAM1
29	glutamate32	7.4	CDH1, KDR, MMP3, TGFA, E2F1, IGFBP3
30	tamoxifen32 34 9 9	10.3	KDR, VEGFA, MUC1, CEACAM3, VIM, CDH1
31	nitric oxide32 9 18 9	10.2	IGF1R, F8, NGFR, TIE1, THBD, PGF
32	actinomycin d32	7.1	VIM, VEGFA, RB1, DES, E2F1, TGFA
33	paclitaxel32 34 9 9	10.0	IGF1R, MDM2, FGF2, FLT4, CDH1, S100B
34	testosterone32 9 18 9	10.0	NCAM1, RB1, VIM, MUC1, S100B, CDH1
35	glutamine32	6.9	IGF1, TGFA, GFAP, F13A1, F8, IGFBP3
36	steroid32	6.7	RB1, S100B, CEACAM3, MDM2, IGF1R, IGF2
37	lactate32	6.7	TGFA, GFAP, SST, F8, IGFBP3, IGF2
38	retinoic acid32 42 18	8.5	NCAM1, SST, NGFR, GFAP, THBD, E2F1
39	alanine32	6.5	CEACAM3, CDH1, MMP3, FGF2, MDM2, IGF1R
40	matrigel32	6.4	FLT4, FGF2, IGF1R, NGFR, ACTC1, GFAP
41	thymidine32 18	7.2	EPB41L3, E2F1, DES, TGFA, MDM2, FGF2
42	cycloheximide32	6.2	IGFBP3, IGF2, VIM, E2F1, IGF1, TGFA
43	creatinine32	6.2	PTGDS, THBD, GFAP, ACTC1, F8, IGF1
44	genistein32 9 18 9	9.1	VIM, VEGFA, KDR, CDH1, TGFA, GFAP
45	estrogen32	5.5	CDH1, CD34, MMP3, FLT4, IGF1R, IGFBP3
46	paraffin32	5.3	GFAP, THBD, TGFA, DES, PGF, ACTC1
47	serine32	5.1	F8, NGFR, NF2, CDH1, GFAP, THBD
48	dexamethasone32 42 34 9 9	8.4	FGF2, FLT4, MMP3, CDH1, S100B, MUC1
49	vegf32	4.3	MMP3, FLT4, FGF2, MDM2, IGF1R, IGF2
50	tyrosine32	3.5	NCAM1, RB1, VEGFA, KDR, MUC1, S100A1

Cellular components related to hemangiopericytoma according to GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	insulin-like growth factor binding protein complex	GO:016942	9.5	IGFBP3, IGF1
2	cell surface	GO:009986	8.6	TGFA, THBD, NGFR, CDH1, VEGFA, NCAM1
3	platelet alpha granule lumen	GO:031093	8.3	F13A1, F8, IGF1, VEGFA
4	extracellular space	GO:005615	6.1	PGF, TGFA, THBD, SST, PTGDS, F8
5	extracellular region	GO:005576	5.5	NCAM1, PGF, NGFR, SST, PTGDS, F13A1

Biological processes related to hemangiopericytoma according to GeneDecks:

(show all 19)

id	Name	GO ID	Score	Top Affiliating Genes
1	negative regulation of transcription involved in G1/S phase of mitotic cell cycle	GO:071930	10.4	RB1, E2F1
2	Bergmann glial cell differentiation	GO:060020	10.2	VIM, GFAP
3	endothelium development	GO:003158	10.1	KDR, CD34
4	cellular response to hypoxia	GO:071456	9.7	E2F1, MDM2, UBE2D1, VEGFA
5	cellular response to vascular endothelial growth factor stimulus	GO:035924	9.5	VEGFA, KDR, FLT4
6	vascular endothelial growth factor receptor signaling pathway	GO:048010	9.4	PGF, FLT4, KDR, VEGFA
7	positive regulation of endothelial cell migration	GO:010595	9.3	FLT4, KDR, VEGFA
8	positive regulation of cerebellar granule cell precursor proliferation	GO:021940	9.3	FGF2, IGF1
9	cell migration involved in sprouting angiogenesis	GO:002042	9.2	FGF2, KDR, VEGFA
10	positive regulation of cell division	GO:051781	9.1	PGF, TGFA, IGF2, FGF2, VEGFA
11	positive regulation of mitosis	GO:045840	9.1	IGF2, IGF1, TGFA
12	positive regulation of angiogenesis	GO:045766	9.1	FGF2, CD34, KDR, VEGFA
13	positive regulation of MAPK cascade	GO:043410	9.0	KDR, FLT4, IGF2, IGFBP3, IGF1
14	positive regulation of endothelial cell proliferation	GO:001938	8.9	PGF, FGF2, FLT4, KDR, VEGFA
15	cellular component movement	GO:006928	8.8	ACTG1, CALD1, IGF1, VIM
16	angiogenesis	GO:001525	8.8	PGF, TGFA, TIE1, KDR, VEGFA
17	anti-apoptosis	GO:006916	8.7	MUC1, IGF1R, IGF1, NGFR, TGFA
18	platelet degranulation	GO:002576	8.6	F13A1, F8, IGF1, VEGFA
19	positive regulation of cell proliferation	GO:008284	7.4	VEGFA, PGF, IGF1, IGF2, IGF1R, MDM2

Molecular functions related to hemangiopericytoma according to GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	structural constituent of cytoskeleton	GO:005200	9.7	DES, GFAP, ACTG1, VIM
2	insulin receptor binding	GO:005158	9.2	IGF1R, IGF2, IGF1
3	identical protein binding	GO:042802	9.0	ACTG1, IGF1R, MDM2, S100B, S100A1, VIM
4	growth factor activity	GO:008083	8.0	PGF, TGFA, IGF1, IGF2, FGF2, VEGFA
5	protein binding	GO:005515	3.8	EPB41L3, IGF1, F8, NGFR, NF2, ACTG1