MCID: HMN013
MIFTS: 54

Hemangiopericytoma malady

Rare diseases, Cancer diseases categories

Summaries for Hemangiopericytoma

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9Disease Ontology, 44NIH Rare Diseases, 66Wikipedia, 34MalaCards
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NIH Rare Diseases:44 Hemangiopericytoma is a term used to described a group of tumors that are derived from pericytes, the cells normally arranged along specific types of blood vessels called capillaries and venules. these types of tumors are typically slow-growing, may be either benign (non-cancerous) or malignant (cancerous), and may occur anywhere in the body. last updated: 11/19/2013

MalaCards: Hemangiopericytoma, also known as hemangiopericytoma, malignant, is related to meningioma and glomus tumor. An important gene associated with Hemangiopericytoma is DES (desmin), and among its related pathways are Aurora B signaling and Response to elevated platelet cytosolic Ca2+. The compounds eosin and toluidine have been mentioned in the context of this disorder. Affiliated tissues include bone, lung and breast, and related mouse phenotypes are muscle and cardiovascular system.

Disease Ontology:9 A soft tissue cancer that is a soft tissue sarcoma and originates in the pericytes in the walls of capillaries.

Wikipedia:66 A hemangiopericytoma (HPC) is a type of soft tissue sarcoma that originates in the pericytes in the... more...

Aliases & Classifications for Hemangiopericytoma

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9Disease Ontology, 44NIH Rare Diseases, 11DISEASES, 46Novoseek, 63UMLS, 41NCIt, 36MeSH, 59SNOMED-CT
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases


Aliases & Descriptions:

hemangiopericytoma 9 44 11 46 63
hemangiopericytoma, malignant 9 63
haemangiopericytic meningioma 9
malignant hemangiopericytoma 9


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Disease Ontology9 DOID:264
NCIt41 C3087
SNOMED-CT59 134335004, 36060005
MeSH36 D006393

Related Diseases for Hemangiopericytoma

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18GeneCards, 19GeneDecks
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Diseases in the Hemangiopericytoma family:

Adult Malignant Hemangiopericytoma

Diseases related to Hemangiopericytoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 149)
idRelated DiseaseScoreTop Affiliating Genes
1meningioma30.6IGF2, PTGDS, VIM, MUC1
2glomus tumor30.4DES, VIM, ACTC1
3infantile myofibromatosis30.4DES
4sarcoma30.3DES, IGF2, F13A1, VIM, MUC1, ACTC1
5liposarcoma30.3DES, VIM
6synovial sarcoma30.3DES, IGF2, VIM, MUC1
7fibrous meningioma30.2MUC1
8adenoma30.1ACTC1, MUC1, IGF2
9endometrial stromal sarcoma30.0ACTC1, VIM, DES
10angiosarcoma30.0VIM, MUC1, ACTC1
11fibrous histiocytoma30.0DES, F13A1, VIM, ACTC1
12mesenchymal chondrosarcoma29.9MUC1, VIM, DES
13chondrosarcoma29.9DES, VIM, MUC1
14papillary carcinoma29.8MUC1, ACTC1
15gastrointestinal stromal tumor29.8DES, VIM, ACTC1
16leiomyoma29.7ACTC1, VIM, IGF2, DES
17neurofibroma29.7F13A1, VIM, MUC1, ACTC1
18meninges hemangiopericytoma10.7
19meningitis10.7
20solitary fibrous tumor10.7
21hypoglycemia10.5
22retroperitoneal hemangiopericytoma10.5
23osteomalacia10.3
24mediastinitis10.3
25hepatitis10.3
26kidney hemangiopericytoma10.3
27malignant mediastinum hemangiopericytoma10.2
28oncogenic osteomalacia10.2
29childhood malignant hemangiopericytoma10.2
30breast hemangiopericytoma10.2
31adult intracranial malignant hemangiopericytoma10.2
32heart malignant hemangiopericytoma10.1
33conventional malignant hemangiopericytoma10.1
34adult malignant hemangiopericytoma10.1
35cervicitis10.1
36histiocytoma10.1
37peritonitis10.1
38pituitary adenoma10.1
39syringoma10.1MUC1
40hidradenoma10.1MUC1
41adenomatoid tumor10.1VIM
42cystadenocarcinoma10.1MUC1
43macular holes10.1PTGDS
44desmoplastic small round cell tumor10.1MUC1, DES
45fasciitis10.1ACTC1
46choroid plexus papilloma10.1IGF2, MUC1
47perineurioma10.1VIM, MUC1
48alveolar soft part sarcoma10.1DES, VIM
49clear cell ependymoma10.1VIM, MUC1
50granular cell tumor10.1DES, VIM

Graphical network of the top 20 diseases related to Hemangiopericytoma:



Diseases related to hemangiopericytoma

Symptoms for Hemangiopericytoma

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Drugs & Therapeutics for Hemangiopericytoma

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

Search CenterWatch for Hemangiopericytoma

Drug clinical trials:

Search ClinicalTrials for Hemangiopericytoma

Search NIH Clinical Center for Hemangiopericytoma

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Genetic Tests for Hemangiopericytoma

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Anatomical Context for Hemangiopericytoma

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34MalaCards
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MalaCards organs/tissues related to Hemangiopericytoma:

34
Bone, Lung, Breast, Liver, Tongue, Pituitary, Kidney, Ovary, Pineal, Heart, Uterus, Spleen, Spinal cord, Adipocyte, Skin, Trachea, Testis, Prostate, Small intestine, Brain, Adrenal gland, Salivary gland, Smooth muscle, Colon, Eye

Animal Models for Hemangiopericytoma or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Hemangiopericytoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053698.3ACTC1, VIM, IGF2, DES
2MP:00053857.5DES, IGF2, F13A1, VIM, ACTC1
3MP:00107687.1DES, IGF2, F13A1, PTGDS, VIM, ACTC1
4MP:00053766.7ACTC1, DES, IGF2, F13A1, PTGDS, VIM

Publications for Hemangiopericytoma

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53PubMed
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Articles related to Hemangiopericytoma:

(show top 50)    (show all 530)
idTitleAuthorsYear
1
Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein. (23575898)
2013
2
Endoscopic Resection of Sinonasal Hemangiopericytoma following Preoperative Embolisation: A Case Report and Literature Review. (23738175)
2013
3
Somatostatin receptor molecular imaging for metastatic intracranial hemangiopericytoma. (24212443)
2013
4
Clinical analysis of intracranial hemangiopericytoma. (24294454)
2013
5
Lipomatous hemangiopericytoma of the stomach: a case report and a review of literature. (22147987)
2011
6
Phase II study of subcutaneous octreotide in adults with recurrent or progressive meningioma and meningeal hemangiopericytoma. (21558077)
2011
7
Hemangiopericytoma in the trigone of the lateral ventricle. (21613766)
2011
8
Intradural hemangiopericytoma of the thoracic spine: a case report. (21641873)
2011
9
Hemangiopericytoma/Solitary fibrous tumor of the oral cavity. (21378362)
2011
10
Retroperitoneal hemangiopericytoma: case report and literature review. (21362325)
2011
11
Hemangiopericytoma: collision with meningioma and recurrence. (20198500)
2010
12
Concurrent Cochlear Implantation with Resection of Skull Base Hemangiopericytoma following Sudden Deafness in an Only Hearing Ear. (21311622)
2010
13
Hemangiopericytoma-solitary fibrous tumour of soft tissue: description of a case showing atypical histological features. (20731251)
2010
14
Inhibiting the VEGF-VEGFR pathway in angiosarcoma, epithelioid hemangioendothelioma, and hemangiopericytoma/solitary fibrous tumor. (20485168)
2010
15
Intradural hemangiopericytoma of the lumbar spine: a rare entity. (18768724)
2009
16
A case of metastatic hemangiopericytoma occurring 16 years after initial presentation: with special reference to the clinical behavior and treatment of metastatic hemangiopericytoma. (19755799)
2009
17
Sudden death due to undiagnosed intracranial hemangiopericytoma. (18520488)
2008
18
Hemangiopericytoma of the Breast: A Case Report. (21048916)
2008
19
Pulmonary lipomatous hemangiopericytoma: report of a rare tumor and comparison with solitary fibrous tumor. (17455098)
2007
20
Metastatic hemangiopericytoma of the skin treated with wide local excision and MGN-3. (16393616)
2006
21
D2-40 staining in sinonasal-type hemangiopericytoma--further evidence of distinction from conventional hemangiopericytoma and solitary fibrous tumor. (16362413)
2006
22
Meningeal hemangiopericytoma manifesting as massive intracranial hemorrhage--two case reports. (16498220)
2006
23
Bone metastasis of intracranial meningeal hemangiopericytoma. (15990973)
2005
24
Preoperative embolization in surgical treatment of a primary hemangiopericytoma of the rib: a case report. (15832008)
2005
25
Case 3. Oncogenic osteomalacia associated with hemangiopericytoma localized by octreotide scan. (15908675)
2005
26
Multiple extracranial metastases from a meningeal hemangiopericytoma and severe hypoglycemia: a case report]. (15227844)
2004
27
Sinonasal-type hemangiopericytoma: a clinicopathologic and immunophenotypic analysis of 104 cases showing perivascular myoid differentiation. (12766577)
2003
28
Oncogenic hypophosphatemic osteomalacia associated with a nasal hemangiopericytoma. (17043447)
2003
29
Solitary fibrous tumor of the oral mucosa--morphological and immunohistochemical profile in the differential diagnosis with hemangiopericytoma. (12676265)
2003
30
Cutaneous malignant hemangiopericytoma with unusual clinical behavior. (12081167)
2002
31
Case of primary malignant hemangiopericytoma of the heart expressing basement membrane-degradable enzymes. (12366815)
2002
32
Intracranial hemangiopericytoma with extracranial metastasis occurring after 22 years. (12160309)
2002
33
Hemangiopericytoma of the parotid gland: CT and MR features. (11419156)
2001
34
Intraocular hemangiopericytoma. A case report. (11528266)
2001
35
Preoperative embolization in surgical treatment of mediastinal hemangiopericytoma. (10750792)
2000
36
Liver angiosarcoma and hemangiopericytoma after occupational exposure to vinyl chloride monomer. (10964802)
2000
37
Fine-needle aspiration cytology of hemangiopericytoma: report of two cases. (10945907)
2000
38
Hemangiopericytoma in children and infants. (10618624)
2000
39
Positron emission tomography in a case of intracranial hemangiopericytoma. (10348440)
1999
40
Cytogenetic, ras, and p53: studies in cases of canine neoplasms (hemangiopericytoma, mastocytoma, histiocytoma, chloroma). (9987918)
1999
41
Oncogenic osteomalacia secondary to a hemangiopericytoma of the hip: case report. (10047746)
1999
42
Hepatic and pulmonary metastases from a meningeal hemangiopericytoma and severe hypoglycemia due to abnormal secretion of insulin-like growth factor: a case report. (10326704)
1999
43
Hemangiopericytoma of the third ventricle. Case report. (9950509)
1999
44
Long-term survival after repetitive surgery for malignant hemangiopericytoma of the lung with subsequent systemic metastases: case report and review of the literature. (9477464)
1997
45
Primary orbital hemangiopericytoma: a case report. (9294920)
1997
46
Meningeal hemangiopericytoma metastatic to the heart. (8776772)
1996
47
Hemangiopericytoma of the masticator space. (8659939)
1996
48
Hemangiopericytoma of the uterus: an unusual cause of the postmenopausal metrorrhagia. (7572113)
1995
49
Giant retroperitoneal hemangiopericytoma. (7494778)
1995
50
Hemangiopericytoma of the uterus vs. hemangiopericytoma-like endometrial stromal sarcoma: a histopathological approach to differential diagnosis. (4054418)
1985

Variations for Hemangiopericytoma

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Expression for genes affiliated with Hemangiopericytoma

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hemangiopericytoma

Search GEO for disease gene expression data for Hemangiopericytoma.

Pathways for genes affiliated with Hemangiopericytoma

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51PathCards, 39NCBI BioSystems Database, 56Reactome, 5Cell Signaling Technology, 54QIAGEN
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Pathways related to Hemangiopericytoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Signaling by Aurora kinases39
Aurora C signaling39
9.6VIM, DES
2
Show member pathways
9.5F13A1, IGF2
39.2ACTC1, IGF2
4
Show member pathways
8.8ACTC1, VIM, DES
58.8ACTC1, VIM, DES
6
Show member pathways
8.7DES, IGF2, VIM, MUC1

Compounds for genes affiliated with Hemangiopericytoma

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46Novoseek, 25HMDB, 3BitterDB, 52PharmGKB, 12DrugBank, 30IUPHAR, 62Tocris Bioscience
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Compounds related to Hemangiopericytoma according to GeneCards/GeneDecks:

(show top 50)    (show all 73)
idCompoundScoreTop Affiliating Genes
1eosin469.9VIM, MUC1
2toluidine469.9VIM, DES
3acetone469.8IGF2, MUC1
4phalloidin469.6DES, VIM
5adriamycin469.5DES, VIM, MUC1
6hyaluronic acid46 2510.5MUC1, VIM, DES
7azathioprine46 3 52 1212.5DES, IGF2, VIM
8gemfibrozil30 46 1211.5DES, VIM
9hydrocortisone46 3 62 1212.4MUC1, VIM, IGF2
1012-o-tetradecanoylphorbol 13-acetate469.4DES, VIM, MUC1
11folate469.4MUC1, VIM, IGF2
12agar469.4IGF2, VIM, MUC1
13chloramphenicol46 3 52 1212.4MUC1, VIM, IGF2
14silver469.3DES, F13A1, PTGDS
15butyrate469.3MUC1, VIM, IGF2
16tamoxifen46 52 30 1212.3IGF2, VIM, MUC1
17orcein469.2ACTC1, VIM, DES
18imatinib46 52 1211.2DES, IGF2, ACTC1
19progestin469.1MUC1, VIM, IGF2, DES
20dihydrotestosterone46 30 25 1212.1DES, IGF2, VIM, MUC1
21actinomycin d469.1DES, IGF2, VIM, MUC1
22estradiol46 25 1211.1MUC1, VIM, IGF2, DES
23forskolin46 52 1211.1MUC1, VIM, IGF2
242-methoxyethanol469.1IGF2, VIM, ACTC1
25ribonucleic acid469.1ACTC1, MUC1, IGF2
26matrigel469.0VIM, MUC1, ACTC1
27heparin46 30 25 1212.0VIM, F13A1, IGF2, DES
28histamine46 30 2510.9VIM, PTGDS, IGF2
29cysteine468.9DES, IGF2, VIM, MUC1
30actomyosin468.8ACTC1, VIM
31mucicarmine468.8DES, VIM, MUC1, ACTC1
32biotin46 25 1210.8ACTC1, MUC1, VIM, DES
33formaldehyde46 259.7DES, VIM, MUC1, ACTC1
34procollagen468.7ACTC1, VIM, F13A1, DES
35iron46 259.6ACTC1, VIM, F13A1, DES
36dexamethasone46 52 30 1211.6IGF2, VIM, MUC1, ACTC1
37glucose468.5ACTC1, MUC1, IGF2, DES
38glycogen46 259.3DES, IGF2, VIM, MUC1, ACTC1
39s 100468.3ACTC1, MUC1, VIM, F13A1, DES
40reticulin468.3DES, F13A1, VIM, MUC1, ACTC1
41b 723468.3DES, F13A1, VIM, MUC1, ACTC1
42hematoxylin468.3ACTC1, MUC1, VIM, F13A1, DES
43calcium46 52 25 1210.9DES, F13A1, PTGDS, MUC1, ACTC1
44paraffin467.8DES, IGF2, F13A1, VIM, MUC1, ACTC1
45progesterone46 30 62 25 1211.8DES, IGF2, F13A1, VIM, MUC1, ACTC1
46vegf467.8DES, IGF2, F13A1, VIM, MUC1, ACTC1
47creatinine467.7DES, IGF2, PTGDS, VIM, MUC1, ACTC1
48testosterone46 62 25 1210.7DES, IGF2, PTGDS, VIM, MUC1, ACTC1
49retinoic acid46 258.7DES, IGF2, PTGDS, VIM, MUC1, ACTC1
50estrogen467.2DES, IGF2, F13A1, PTGDS, VIM, MUC1

GO Terms for genes affiliated with Hemangiopericytoma

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17Gene Ontology
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Cellular components related to Hemangiopericytoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1intermediate filamentGO:0058829.6VIM, DES
2platelet alpha granule lumenGO:0310939.2F13A1, IGF2

Biological processes related to Hemangiopericytoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to ethanolGO:0454719.2ACTC1, IGF2
2platelet degranulationGO:0025769.2F13A1, IGF2
3muscle filament slidingGO:0300498.7ACTC1, VIM, DES

Molecular functions related to Hemangiopericytoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of cytoskeletonGO:0052009.6VIM, DES

Products for genes affiliated with Hemangiopericytoma

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Sources for Hemangiopericytoma

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet