Summaries for Hemarthrosis

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Wikipedia:63 Hemarthrosis (or haemarthrosis, plural h(a)emarthroses) is a bleeding into joint spaces. more...

MalaCards based summary: Hemarthrosis, also known as hemarthrosis of shoulder region, is related to glanzmann thrombasthenia and factor x deficiency. An important gene associated with Hemarthrosis is F9 (coagulation factor IX), and among its related pathways are PTM- gamma carboxylation, hypusine formation and arylsulfatase activation and Response to elevated platelet cytosolic Ca2+. The compounds recombinate and kogenate have been mentioned in the context of this disorder. Affiliated tissues include bone, skeletal muscle and myeloid, and related mouse phenotype homeostasis/metabolism.

Aliases & Classifications for Hemarthrosis

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Hemarthrosis, Aliases & Descriptions:

Name: Hemarthrosis 9 11 43 60
Hemarthrosis of Shoulder Region 9 60
Hemarthrosis of Upper Arm 9 60
Hemarthrosis of Lower Leg 9 60
Hemarthrosis of Forearm 9 60
Hemarthrosis of Hand 9 60
Hemarthrosis Involving Pelvic Region and Thigh 9
Haemarthrosis of the Pelvic Region and Thigh 9
Hemarthrosis of the Pelvic Region and Thigh 9
Hemarthrosis Involving Shoulder Region 9
Hemarthrosis of the Ankle and/or Foot 9
Hemarthrosis Involving Ankle and Foot 9
Haemarthrosis of the Ankle and Foot 9
Hemarthrosis of the Shoulder Region 9
 
Hemarthrosis of Glenohumeral Joint 60
Hemarthrosis of the Ankle and Foot 9
Hemarthrosis of Ankle and/or Foot 9
Hemarthrosis Involving Lower Leg 9
Hemarthrosis Involving Upper Arm 9
Haemarthrosis of Shoulder Joint 9
Hemarthrosis Involving Forearm 9
Hemarthrosis of the Lower Leg 9
Hemarthrosis of the Upper Arm 9
Hemarthrosis of the Forearm 9
Hemarthrosis Involving Hand 9
Hemarthrosis of Shoulder 9
Hemarthrosis of the Hand 9


External Ids:

Disease Ontology9 DOID:801
MeSH33 D006395
ICD9CM27 719.1, 719.10

Related Diseases for Hemarthrosis

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Diseases related to Hemarthrosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 98)
idRelated DiseaseScoreTop Affiliating Genes
1glanzmann thrombasthenia30.7VWF
2factor x deficiency30.4F3, F10, F9
3arthropathy30.4F9, F8
4acute myocardial infarction30.3F3, F10, VWF
5factor v deficiency30.2F8, F3
6amyloidosis30.1F10, F9
7myocardial infarction29.7F8, F3, F10, F9, VWF
8hemophilia b29.7F8, F3, F10, F9
9hemophilia a29.6VWF, F9, F10, F3, F8
10systemic lupus erythematosus29.6VWF, F10, F3, F8
11hemorrhagic disease29.4VWF, F9, F10, F3, F8
12hemophilia10.5
13cardiac tamponade10.4F8
14thrombophlebitis10.4F8
15angiodysplasia10.4VWF
16carotid artery thrombosis10.4F3
17synovitis10.4
18arthritis10.3
19scurvy10.2
20protein s deficiency10.2F8, F3
21thrombasthenia10.2
22aneurysm10.2
23peripheral vascular disease10.2F3, VWF
24viral hepatitis10.2F8, F10
25atrial fibrillation10.2F10, VWF
26sickle cell disease10.2F9, VWF
27coronary thrombosis10.1F3, VWF
28stroke, ischemic10.1F3, VWF
29bladder cancer, somatic10.1F10, F9
30lipoma10.1
31osteoarthritis10.1
32pigmented villonodular synovitis10.1
33villonodular synovitis10.1
34purpura10.1
35acquired hemophilia10.1
36blindness10.1
37hypercholesterolemia, familial10.1F8, F10, F9
38factor xi deficiency, autosomal recessive10.1F8, F3, F9
39pulmonary embolism10.1F3, F10, F9
40factor viii deficiency10.1F9, F3, F8
41hemolytic anemia10.1VWF, F3
42hepatitis10.1F8, F10, F9
43bernard-soulier syndrome, type c10.1VWF, F9, F8
44hyperhomocysteinemia10.0VWF, F9, F8
45factor xii deficiency10.0VWF, F9, F3
46factor xiii deficiency10.0F3, F13B
47hypothyroidism10.0VWF, F9, F8
48blood platelet disease10.0VWF, F10, F8
49liver cirrhosis10.0F9, F10, F3
50thrombocytosis10.0F3, F10, VWF

Graphical network of the top 20 diseases related to Hemarthrosis:



Diseases related to hemarthrosis

Symptoms for Hemarthrosis

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Drugs & Therapeutics for Hemarthrosis

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Drug clinical trials:

Search ClinicalTrials for Hemarthrosis

Search NIH Clinical Center for Hemarthrosis

Genetic Tests for Hemarthrosis

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Anatomical Context for Hemarthrosis

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MalaCards organs/tissues related to Hemarthrosis:

31
Bone, Skeletal muscle, Myeloid, Monocytes, B cells

Animal Models for Hemarthrosis or affiliated genes

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MGI Mouse Phenotypes related to Hemarthrosis:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053767.9F8, F3, F10, F9, VWF

Publications for Hemarthrosis

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Articles related to Hemarthrosis:

(show top 50)    (show all 207)
idTitleAuthorsYear
1
Spontaneous hemarthrosis following fibrinolytic therapy for acute myocardial infarction: a case report and literature review. (25417208)
2014
2
Occult Intra-articular Knee Injuries in Children With Hemarthrosis. (24753236)
2014
3
Hemarthrosis in hemophilic mice results in alterations in M1-M2 monocyte/macrophage polarization. (24252538)
2013
4
Antiplasmin, but not amiloride, prevents synovitis and cartilage damage following hemarthrosis in hemophilic mice. (24283895)
2013
5
Knee hemarthrosis after arthroscopic surgery in an athlete with low factor XIII activity. (23031577)
2012
6
Spontaneous recurrent hemarthrosis of the knee joint in the elderly: a report of two cases. (21607723)
2012
7
MRI findings in adolescent patients with acute traumatic knee hemarthrosis. (23147616)
2012
8
Intra-articular nodular fasciitis of the knee: a rare cause of recurrent hemarthrosis. (21431289)
2012
9
A rare case of meniscal hematoma with hemarthrosis of the knee: a case report. (21938355)
2011
10
Glanzmann thrombasthenia detected because of knee hemarthrosis: a case report. (20736850)
2010
11
Hemarthrosis due to a rare cause of hemorrhagic diathesis: Ehlers-Danlos syndrome. (18432503)
2008
12
A case of delayed recurrent hemarthrosis after posterolateral reconstruction of the knee with a staple fixation at the lateral femoral epicondyle. (18365223)
2008
13
Embolization of spontaneous hemarthrosis post total knee replacement. (18185956)
2008
14
In vitro multipotentiality and characterization of human unfractured traumatic hemarthrosis-derived progenitor cells: A potential cell source for tissue repair. (17171634)
2007
15
Recurrent hemarthrosis after knee joint arthroplasty: etiology and treatment. (14973857)
2004
16
Hemarthrosis and scurvy. (12180758)
2002
17
Yersinia enterocolitica O:3 infection of a prosthetic knee joint related to recurrent hemarthrosis. (11928845)
2002
18
Spontaneous hemarthrosis 6 years after total knee arthroplasty. (11172285)
2001
19
Hemarthrosis as initial presentation of scurvy. (11508601)
2001
20
Cytogenetic studies in patients with hemophilic hemarthrosis treated by 198Au, 186Rh, and 90Y radioactive synoviorthesis. (10647112)
2000
21
Recurrent spontaneous hemarthrosis associated with reflex sympathetic dystrophy. (9523789)
1998
22
Hemarthrosis and hip joint pressure in femoral neck fractures. (9728169)
1998
23
Recurrent acute hemarthrosis after anterior cruciate ligament reconstruction. Report of an unusual complication and a review of the literature. (8739716)
1996
24
Cuff tear arthropathy with hemarthrosis. A report on 3 elderly patients. (9065069)
1996
25
Surgical orthopedic correction of hemophilic hemarthrosis at Ramathibodi Hospital. (7886589)
1993
26
Recurrent spontaneous hemarthrosis nine years after a total knee arthroplasty. A presentation with pigmented villonodular synovitis. (8501094)
1993
27
Acute traumatic knee hemarthrosis. (8461076)
1993
28
Recurrent hemarthrosis associated with gout. (1555350)
1992
29
Reduction and osteosynthesis of subcapital fractures of the femoral neck: possible repercussions on post-fracture hemarthrosis of the hip. (1345649)
1992
30
Hemarthrosis in patients with acquired factor VIII inhibitor. (1902518)
1991
31
Hemarthrosis of the ankle secondary to false aneurysm caused by impingement from an osteophyte. A case report. (2745490)
1989
32
Late hemarthrosis from a threaded acetabular component. (3361321)
1988
33
Hemarthrosis after femoral neck fracture fixation. (3188856)
1988
34
The significance of hemarthrosis of the knee in children. (3358674)
1988
35
Spontaneous hemarthrosis associated with an exostosis of the talus. (3572920)
1987
36
Differentiating pyogenic arthritis from spontaneous hemarthrosis in patients with hemophilia. (3953068)
1986
37
Intracapsular pressure and hemarthrosis following femoral neck fracture. (6692612)
1984
38
The presence of siderosomes in synovioblasts (B cells) of chronic spontaneous hemarthrosis. Histologic, electron microscopic, and roentgenographic electron microanalysis studies of three cases. (6548901)
1984
39
Hemarthrosis in an heparinized patient. (856220)
1977
40
Letter: Hemarthrosis secondary to heparin therapy. (962976)
1976
41
On the pathogenesis of hemophilic hemarthrosis]. (808446)
1975
42
Hemarthrosis. (1053879)
1975
43
Management of hemarthrosis. (5440065)
1970
44
Double-blind studies on the use of steroids in the treatment of acute hemarthrosis in patients with hemophilia. (4907066)
1970
45
Chronic myeloid leukemia with hemarthrosis. A case report. (5231484)
1967
46
Experimental hemarthrosis. The response of canine knees to injections of autologous blood. (6018731)
1967
47
Hemarthrosis complicating anticoagulant therapy. Report of three cases. (5952425)
1966
48
Experimental hemarthrosis: the removal of chromium-51- and iron-59-labeled erythrocytes injected into the knee joint of rabbit and man. (14438187)
1960
49
Some observations on experimental hemarthrosis and the pathogenesis of hemophilic arthritis. (14438188)
1959
50
The use of hyaluronidase in the treatment of acute hemophilic hemarthrosis. (13035639)
1953

Variations for Hemarthrosis

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Expression for genes affiliated with Hemarthrosis

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Search GEO for disease gene expression data for Hemarthrosis.

Pathways for genes affiliated with Hemarthrosis

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Pathways related to Hemarthrosis according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.7F10, F9
2
Show member pathways
9.5F8, VWF
3
Show member pathways
7.8F9, F13B, F10, F3, F8
4
Show member pathways
7.3VWF, F9, F13B, F10, F3, F8
5
Show member pathways
Complement Activation, Classical Pathway36
Complement and Coagulation Cascades36
7.3VWF, F9, F13B, F10, F3, F8
6
Show member pathways
7.3F8, F3, F10, F13B, F9, VWF

Compounds for genes affiliated with Hemarthrosis

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Compounds related to Hemarthrosis according to GeneCards Suite gene sharing:

(show top 50)    (show all 103)
idCompoundScoreTop Affiliating Genes
1recombinate439.8F8, VWF
2kogenate439.8F8, VWF
3echicetin439.7VWF, F9
4tributylphosphate439.6F8, F9, VWF
5roxifiban439.5F3, F10
6ivig439.4VWF, F9, F8
7dabigatran49 4310.3F10, F3
8organon439.3F9, F10, F3
9fondaparinux439.3F9, F10, F3
10rituximab43 49 1211.3VWF, F9, F8
11coumarins439.3F9, F10, F3
12efegatran439.2F10, F3
13ecarin439.2F3, F10
14gamma-carboxyglutamic acid439.2F3, F10, F9
15coumarin43 2 49 2412.2F9, F10, F3
16rfviii439.2F8, F10, F9, VWF
17dextran sulfate439.2F3, F10, F9
18desirudin439.1F10, F3
19tinzaparin43 1210.1VWF, F10, F3
20acetaminophen43 2 49 24 1213.1F8, F10, F9, VWF
21ppack439.1F3, F10, VWF
22cardiolipin43 1210.1F10, F3, F8
23tirofiban43 1210.1F3, F10, VWF
24abciximab43 1210.1F3, F10, VWF
25hydroxyethyl starch439.1VWF, F3, F8
26clopidogrel43 49 24 1212.1F3, F10, VWF
27kininogen439.0VWF, F9, F3
28guanidine hydrochloride438.9F3, F10, VWF
29kaolin438.9F9, F10, F3, F8
30cacl2438.9F9, F10, F3, F8
31dermatan sulfate438.8F3, F10, F9, VWF
32aprotinin43 129.7VWF, F9, F10, F3
33tranexamic acid43 129.7F8, F3, F9, VWF
34ristocetin438.7F8, F3, F9, VWF
35desmopressin43 59 28 1211.7VWF, F9, F3, F8
36homocysteine43 249.7VWF, F9, F3, F8
37cyclophosphamide43 49 1210.7VWF, F9, F3, F8
38aspirin43 49 28 2411.6VWF, F10, F3, F8
39glutamine438.4VWF, F9, F10, F8
40hirudin438.3VWF, F9, F10, F3, F8
41warfarin43 49 24 1211.3VWF, F9, F10, F3, F8
42citrate438.3VWF, F9, F10, F3, F8
43phosphatidylserine43 28 1210.3VWF, F9, F10, F3, F8
44fibrinogen438.3VWF, F9, F10, F3, F8
45phospholipid438.3F8, F3, F10, F9, VWF
46aspartate438.3VWF, F9, F10, F3, F8
47heparin43 28 24 1211.3VWF, F9, F10, F3, F8
48alanine438.2VWF, F9, F10, F3, F8
49adp43 28 2410.2VWF, F9, F10, F3, F8
50cysteine438.1VWF, F9, F10, F3, F8

GO Terms for genes affiliated with Hemarthrosis

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Cellular components related to Hemarthrosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1Golgi lumenGO:00057969.7F10, F9
2intrinsic component of external side of plasma membraneGO:00312339.2F3, F10
3platelet alpha granule lumenGO:00310939.2F8, VWF
4extracellular regionGO:00055768.0VWF, F9, F13B, F10, F8

Biological processes related to Hemarthrosis according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1peptidyl-glutamic acid carboxylationGO:00171879.7F10, F9
2platelet degranulationGO:00025769.5F8, VWF
3positive regulation of protein kinase B signalingGO:00518978.9F3, F10
4blood coagulation, extrinsic pathwayGO:00075988.9F9, F10, F3
5cell adhesionGO:00071558.9VWF, MSLNL, F8
6blood coagulation, intrinsic pathwayGO:00075978.9F8, F10, F9, VWF
7blood coagulationGO:00075967.4VWF, F9, F13B, F10, F3, F8

Molecular functions related to Hemarthrosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1phospholipid bindingGO:00055439.2F3, F10
2serine-type endopeptidase activityGO:00042529.1F8, F10, F9
3protease bindingGO:00020208.8F3, VWF

Products for genes affiliated with Hemarthrosis

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Sources for Hemarthrosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet