MCID: HMT018
MIFTS: 41

Hematopoietic Stem Cell Transplantation malady

Blood category

Summaries for Hematopoietic Stem Cell Transplantation

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64Wikipedia, 33MalaCards
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Wikipedia:64 Hematopoietic stem cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem... more...

MalaCards: Hematopoietic Stem Cell Transplantation is related to acute graft versus host disease and hepatitis c. An important gene associated with Hematopoietic Stem Cell Transplantation is KIR2DS3 (killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3), and among its related pathways are Allograft rejection and Immune response Fc epsilon RI pathway. Affiliated tissues include skin, liver and tongue.

Aliases & Classifications for Hematopoietic Stem Cell Transplantation

Sources:
49Orphanet, 26ICD10 via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Blood


Characteristics (Orphanet epidemiological data):

49

Aliases & Descriptions:

hematopoietic stem cell transplantation 49


External Ids:

ICD10 via Orphanet26 Z94.8

Related Diseases for Hematopoietic Stem Cell Transplantation

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Hematopoietic Stem Cell Transplantation via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 273)
idRelated DiseaseScoreTop Affiliating Genes
1acute graft versus host disease31.7HMHA1, KIR3DL1
2hepatitis c31.1KIR2DL3, KIR3DL1
3t-cell leukemia11.3
4graft versus host disease11.3
5acute t cell leukemia11.2
6acute leukemia11.2
7chronic graft versus host disease11.0
8bronchiolitis obliterans11.0
9bronchiolitis11.0
10aplastic anemia11.0
11adult t-cell leukemia10.9
12t cell deficiency10.9
13aspergillosis10.9
14invasive aspergillosis10.9
15leukemia, t-cell, chronic10.9
16acute myeloid leukemia10.9
17engraftment syndrome10.8
18leukemia/lymphoma, t-cell10.8
19adult lymphoma10.8
20thalassemia10.8
21juvenile myelomonocytic leukemia10.8
22chronic myeloid leukemia10.8
23cytomegalovirus infection10.7
24hemophagocytic lymphohistiocytosis10.7
25chronic granulomatous disease10.7
26myelodysplastic syndromes10.7
27osteopetrosis10.7
28wiskott-aldrich syndrome10.7
29bacteremia10.7
30n syndrome10.6
31hepatitis a10.6
32leukemia, b-cell, chronic10.6
33hepatitis c virus10.6
34diffuse alveolar hemorrhage10.6
35dyskeratosis congenita10.6
36leukocyte adhesion deficiency10.6
37follicular lymphoma10.6
38peripheral t-cell lymphoma10.6
39t cell immunodeficiency primary10.6
40adrenoleukodystrophy10.6
41acute lymphocytic leukemia10.6
42thrombocytopenia10.6
43post-transplant lymphoproliferative disease10.6
44lymphocytic leukemia, acute t-cell10.6
45fusariosis10.5
46severe congenital neutropenia10.5
47autoimmune hemolytic anemia10.5
48amyloidosis10.5
49sickle cell disease10.5
50acute promyelocytic leukemia10.5

Graphical network of the top 20 diseases related to Hematopoietic Stem Cell Transplantation:



Diseases related to hematopoietic stem cell transplantation

Clinical Features for Hematopoietic Stem Cell Transplantation

Drugs & Therapeutics for Hematopoietic Stem Cell Transplantation

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Hematopoietic Stem Cell Transplantation

Drug clinical trials:

Search ClinicalTrials for Hematopoietic Stem Cell Transplantation

Search NIH Clinical Center for Hematopoietic Stem Cell Transplantation

Search CenterWatch for Hematopoietic Stem Cell Transplantation

Genetic Tests for Hematopoietic Stem Cell Transplantation

Anatomical Context for Hematopoietic Stem Cell Transplantation

Sources:
33MalaCards
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MalaCards organs/tissues related to Hematopoietic Stem Cell Transplantation:

33
Skin, Liver, Tongue, Brain, Kidney, Lung, Bone marrow, Whole blood, Thymus, Heart, Skeletal muscle, Small intestine, Colon, Thyroid, Salivary gland, Breast, Myeloid, Monocytes, Nk cells, T cells, B lymphoblasts, B cells, Endothelial

Animal Models for Hematopoietic Stem Cell Transplantation or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Hematopoietic Stem Cell Transplantation

Sources:
51PubMed
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Articles related to Hematopoietic Stem Cell Transplantation:

(show top 50)    (show all 1240)
idTitleAuthorsYear
1
Proceedings from the National Cancer Institute's Second International Workshop on the Biology, Prevention, and Treatment of Relapse after Hematopoietic Stem Cell Transplantation: Part III. Prevention and Treatment of Relapse after Allogeneic Transplantation. (24018392)
2014
2
EBV Load in Whole Blood Correlates With LMP2 Gene Expression After Pediatric Heart Transplantation or Allogeneic Hematopoietic Stem Cell Transplantation. (24389909)
2014
3
Role of hematopoietic stem cell transplantation for relapsed acute promyelocytic leukemia: a retrospective analysis of JALSG-APL97. (23837667)
2013
4
Lung function and airway inflammation monitoring after hematopoietic stem cell transplantation. (24169073)
2013
5
Long-Term Results of Autologous Hematopoietic Stem-Cell Transplantation After High-Dose 90Y-Ibritumomab Tiuxetan for Patients With Poor-Risk Non-Hodgkin Lymphoma Not Eligible for High-Dose BEAM. (23857974)
2013
6
Safety of hematopoietic stem cell transplantation from hepatitis B core antibodies-positive donors with low/undetectable viremia in HBV-naA^ve children. (24078025)
2013
7
Multiple mismatches at the low expression HLA loci DP, DQ, and DRB3/4/5 associate with adverse outcomes in hematopoietic stem cell transplantation. (23596045)
2013
8
Murine NK-cell licensing is reflective of donor MHC-I following allogeneic hematopoietic stem cell transplantation in murine cytomegalovirus responses. (23818546)
2013
9
Expression of SOCS1 and SOCS3 genes in human graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. (23589790)
2013
10
Renal arteriolar C4d deposition: a novel characteristic of hematopoietic stem cell transplantation-associated thrombotic microangiopathy. (23698598)
2013
11
Psychosocial factors and hematopoietic stem cell transplantation: potential biobehavioral pathways. (23845514)
2013
12
Measurement of circulating endothelial cells to support the diagnosis of veno-occlusive disease after hematopoietic stem cell transplantation. (23981391)
2013
13
Successful treatment of a patient with adult T cell leukemia/lymphoma using anti-CC chemokine receptor 4 monoclonal antibody mogamulizumab followed by allogeneic hematopoietic stem cell transplantation. (23801427)
2013
14
Growth after hematopoietic stem cell transplantation in children with acute myeloid leukemia. (23341720)
2013
15
Incidence and risk factors for early-onset hypertension after allogeneic hematopoietic stem cell transplantation in children. (24385991)
2013
16
Bone Marrow Graft-versus-Host Disease: Evaluation of Its Clinical Impact on Disrupted Hematopoiesis after Allogeneic Hematopoietic Stem Cell Transplantation. (24374213)
2013
17
Ferritin concentrations correlate to outcome of hematopoietic stem cell transplantation but do not serve as biomarker of graft-versus-host disease. (23604429)
2013
18
Diagnosis and treatment of viral diseases in recipients of allogeneic hematopoietic stem cell transplantation. (24341630)
2013
19
The effectiveness of tacrolimus and minidose methotrexate in the prevention of acute graft-versus-host disease following allogeneic hematopoietic stem cell transplantation in children: a single-center study in Korea. (22783357)
2012
20
Both optimal matching and procedure duration influence survival of patients after unrelated donor hematopoietic stem cell transplantation. (23243511)
2012
21
Pretransplant serum ferritin level may be a predictive marker for outcomes in patients having undergone allogeneic hematopoietic stem cell transplantation. (22248276)
2012
22
Immune-mediated peripheral neuropathy occurring simultaneously with recurrent graft-versus-host disease after allogenic hematopoietic stem cell transplantation. (22177946)
2012
23
Syngeneic donor hematopoietic stem cell transplantation is associated with high rates of engraftment syndrome. (20870027)
2011
24
Allogeneic hematopoietic stem cell transplantation for acute leukemia with Gilbert's syndrome. (21388537)
2011
25
Higher proportions of peripheral CD19+CD5+ B cells predict the effect of corticosteroid in patients with late-onset hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation. (21740809)
2011
26
Hematopoietic stem cell transplantation for chronic granulomatous disease. (20493396)
2010
27
Influence of CYP3A5 and ABCB1 gene polymorphisms on calcineurin inhibitor-related neurotoxicity after hematopoietic stem cell transplantation. (20030680)
2010
28
Increased serum levels of high-mobility group box 1 protein in patients who developed acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. (20659154)
2010
29
Technology Insight: hematopoietic stem cell transplantation for systemic rheumatic disease. (18285764)
2008
30
Erythroid-lineage-specific engraftment in patients with severe hemoglobinopathy following allogeneic hematopoietic stem cell transplantation. (18550258)
2008
31
Bone marrow-derived mesenchymal stem cells decrease acute graft-versus-host disease after allogeneic hematopoietic stem cells transplantation. (18214798)
2008
32
Decreased risk of acute graft-versus-host disease following allogeneic hematopoietic stem cell transplantation in patients with the 5,10-methylenetetrahydrofolate reductase 677TT genotype. (18365141)
2008
33
Growth and differentiation advantages of CD4+ OX40+ T cells from allogeneic hematopoietic stem cell transplantation recipients. (18275893)
2008
34
Hematopoietic stem cell transplantation for Hodgkin's disease in a patient with dysfibrinogenemia and thrombosis. (17131175)
2007
35
Risk factors for acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation: retrospective analysis of 73 patients who received cyclosporin A. (17724440)
2007
36
Impact of cumulative anthracycline dose, preparative regimen and chronic graft-versus-host disease on pulmonary and cardiac function in children 5 years after allogeneic hematopoietic stem cell transplantation: a prospective evaluation on behalf of the EBMT Pediatric Diseases and Late Effects Working Parties. (17401396)
2007
37
An antecedent diagnosis of refractory anemia with excess blasts has no influence on mobilization of peripheral blood stem cells and hematopoietic recovery after autologous stem cell transplantation in acute myeloid leukemia. (17042770)
2007
38
Successful mobilization and transplantation of filgrastim mobilized hematopoietic stem cells in sickle cell-hemoglobin C disease. (16708064)
2006
39
Engraftment syndrome after nonmyeloablative allogeneic hematopoietic stem cell transplantation: incidence and effects on survival. (15983554)
2005
40
Role of fibrinolytic and clotting parameters in the diagnosis of liver veno-occlusive disease after hematopoietic stem cell transplantation in a pediatric population. (15841312)
2005
41
Hematopoietic stem cell transplantation for de novo acute megakaryocytic leukemia in first complete remission: a retrospective study of the European Group for Blood and Marrow Transplantation (EBMT). (15191953)
2005
42
Inflammatory myofibroblastic tumor following hematopoietic stem cell transplantation: report of two pediatric cases. (14647262)
2004
43
Graft-versus-Tax response in adult T-cell leukemia patients after hematopoietic stem cell transplantation. (14729650)
2004
44
Anti-thrombin III in the management of hematopoietic stem-cell transplantation-associated toxicity. (15113990)
2004
45
Hematopoietic recovery after unrelated umbilical cord-blood allogeneic transplantation in adults treated with in vivo stem cell factor (R-MetHuSCF) and filgrastim administration. (12537973)
2003
46
Genetic protection of repopulating hematopoietic cells with an improved MDR1-retrovirus allows administration of intensified chemotherapy following stem cell transplantation in mice. (11920652)
2002
47
Autologous hematopoietic stem cell transplantation suppresses Gd-enhanced MRI activity in MS. (11445629)
2001
48
Idiopathic giant cell myocarditis after autologous hematopoietic stem cell transplantation and interleukin-2 immunotherapy: a case report. (9740090)
1998
49
Towards a standardization of the culture of hematopoietic progenitor cells CFU-GM applied to the transplantation of hematopoietic stem cells in France]. (7767478)
1995
50
Long-term expression of human argininosuccinate synthetase in mice following bone marrow transplantation with retrovirus-transduced hematopoietic stem cells. (1562637)
1992

Genetic Variations for Hematopoietic Stem Cell Transplantation

Expression for genes affiliated with Hematopoietic Stem Cell Transplantation

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hematopoietic Stem Cell Transplantation

Search GEO for disease gene expression data for Hematopoietic Stem Cell Transplantation.

Pathways for genes affiliated with Hematopoietic Stem Cell Transplantation

Sources:
30KEGG, 12EMD Millipore, 54Reactome
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Compounds for genes affiliated with Hematopoietic Stem Cell Transplantation

GO Terms for genes affiliated with Hematopoietic Stem Cell Transplantation

Sources:
16Gene Ontology
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Cellular components related to Hematopoietic Stem Cell Transplantation according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1plasma membraneGO:00588611.3KIR2DS2, KIR2DL2, KIR2DL5A, KIR2DL1, KIR3DL2, KIR3DS1
2integral to plasma membraneGO:00588710.7KIR2DS5, KIR2DL3, KIR3DL2, KIR2DL1, KIR2DS3, KIR3DS1

Biological processes related to Hematopoietic Stem Cell Transplantation according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1regulation of immune responseGO:05077611.0KIR3DL1, KIR2DL3, KIR3DL2, KIR2DL1, KIR2DL2, KIR2DS2
2immune responseGO:00695510.8KIR2DL3, KIR2DL1, KIR2DS2, KIR3DS1, KIR2DS1, KIR3DL1
3innate immune responseGO:04508710.8KIR2DS5, KIR2DS4, KIR2DS1, KIR3DS1, KIR2DS2
4cellular defense responseGO:00696810.4KIR3DL2, KIR2DS3, KIR2DL4

Molecular functions related to Hematopoietic Stem Cell Transplantation according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1transmembrane signaling receptor activityGO:00488810.7KIR2DS1, KIR2DL4, KIR2DS2

Products for genes affiliated with Hematopoietic Stem Cell Transplantation

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Sources for Hematopoietic Stem Cell Transplantation

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet