MCID: HMT018
MIFTS: 40

Hematopoietic Stem Cell Transplantation malady

Rare diseases, Blood diseases categories

Summaries for Hematopoietic Stem Cell Transplantation

About this section
Sources:
66Wikipedia, 34MalaCards
See all sources

Fully expand this MalaCard

Download this MalaCard
Wikipedia:66 Hematopoietic stem cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem... more...

MalaCards: Hematopoietic Stem Cell Transplantation is related to graft versus host disease and acute graft versus host disease. An important gene associated with Hematopoietic Stem Cell Transplantation is KIR2DS3 (killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3), and among its related pathways are Signaling by FGFR and Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell. Affiliated tissues include t cells, bone and myeloid.

Aliases & Classifications for Hematopoietic Stem Cell Transplantation

About this section
Sources:
50Orphanet, 27ICD10 via Orphanet
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Blood diseases


Characteristics (Orphanet epidemiological data):

50

Aliases & Descriptions:

hematopoietic stem cell transplantation 50


External Ids:

ICD10 via Orphanet27 Z94.8

Related Diseases for Hematopoietic Stem Cell Transplantation

About this section
Sources:
18GeneCards, 19GeneDecks
See all sources

Graphical network of the top 20 diseases related to Hematopoietic Stem Cell Transplantation:



Diseases related to hematopoietic stem cell transplantation

Symptoms for Hematopoietic Stem Cell Transplantation

About this section

Drugs & Therapeutics for Hematopoietic Stem Cell Transplantation

About this section
Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Hematopoietic Stem Cell Transplantation

Drug clinical trials:

Search ClinicalTrials for Hematopoietic Stem Cell Transplantation

Search NIH Clinical Center for Hematopoietic Stem Cell Transplantation

Search CenterWatch for Hematopoietic Stem Cell Transplantation

Genetic Tests for Hematopoietic Stem Cell Transplantation

About this section

Anatomical Context for Hematopoietic Stem Cell Transplantation

About this section
Sources:
34MalaCards
See all sources

MalaCards organs/tissues related to Hematopoietic Stem Cell Transplantation:

34
T cells, Bone, Myeloid, Bone marrow, B cells, Lung, Endothelial, Liver, Nk cells, Skin, Kidney, Breast, Heart, Thyroid, Colon, Thymus, Testes, Monocytes, Brain, Whole blood, Eye, Tongue, Skeletal muscle

Animal Models for Hematopoietic Stem Cell Transplantation or affiliated genes

About this section

Publications for Hematopoietic Stem Cell Transplantation

About this section
Sources:
53PubMed
See all sources

Articles related to Hematopoietic Stem Cell Transplantation:

(show top 50)    (show all 1284)
idTitleAuthorsYear
1
Association between busulfan exposure and outcome in children receiving intravenous busulfan before hematopoietic stem cell transplantation. (24061446)
2014
2
Cognitive and psychosocial function post hematopoietic stem cell transplantation in children with hemophagocytic lymphohistiocytosis. (23987797)
2013
3
Role of hematopoietic stem cell transplantation for relapsed acute promyelocytic leukemia: a retrospective analysis of JALSG-APL97. (23837667)
2013
4
Allogeneic hematopoietic stem cell transplantation for children with severe aplastic anemia. (23724451)
2013
5
Genetically Modified Hematopoietic Stem Cell Transplantation for HIV-1-infected Patients: Can We Achieve a Cure? (24220323)
2013
6
Combination of fludarabine, amsacrine, and cytarabine followed by reduced-intensity conditioning and allogeneic hematopoietic stem cell transplantation in patients with high-risk acute myeloid leukemia. (23728608)
2013
7
Treatment of disease recurrence after allogeneic hematopoietic stem cell transplantation in children with juvenile myelomonocytic leukemia: a great challenge still to be won. (22976832)
2013
8
Skeletal abnormalities and successful hematopoietic stem cell transplantation in patients with reticular dysgenesis. (23763981)
2013
9
Immunosuppressive CD14+HLA-DRlow/neg IDO+ myeloid cells in patients following allogeneic hematopoietic stem cell transplantation. (22828446)
2013
10
Bone marrow-derived endothelial progenitor cells promote hematopoietic reconstitution after hematopoietic stem cell transplantation. (23375333)
2013
11
Luminex(Ar) and its applications for solid organ transplantation, hematopoietic stem cell transplantation, and transfusion. (23922543)
2013
12
Gauchers disease--a reappraisal of hematopoietic stem cell transplantation. (23363328)
2013
13
Nutritional assessment with different tools in leukemia patients after hematopoietic stem cell transplantation. (24385706)
2013
14
Roseomonas bacteremia in a recipient of an allogeneic hematopoietic stem cell transplantation. (23725464)
2013
15
Strategies for induction, autologous hematopoietic stem cell transplantation, consolidation, and maintenance for transplantation-eligible multiple myeloma patients. (24319224)
2013
16
Risk factors for bronchiolitis obliterans syndrome in allogeneic hematopoietic stem cell transplantation. (23823823)
2013
17
Peripheral T-cell lymphoma: The role of hematopoietic stem cell transplantation. (24075060)
2013
18
Lung function and airway inflammation monitoring after hematopoietic stem cell transplantation. (24169073)
2013
19
Clinical relevance of natural killer cells following hematopoietic stem cell transplantation. (23386902)
2013
20
Evaluation of risk for graft-versus-host disease in children who receive less than the full doses of mini-dose methotrexate for graft-versus-host disease prophylaxis in allogeneic hematopoietic stem cell transplantation. (24348662)
2013
21
Long-term follow-up of reduced-intensity allogeneic hematopoietic stem cell transplantation for refractory or relapsed follicular lymphoma. (22674621)
2012
22
Graft invariant natural killer T-cell dose predicts risk of acute graft-versus-host disease in allogeneic hematopoietic stem cell transplantation. (22371885)
2012
23
Comparison between matched related and alternative donors of allogeneic hematopoietic stem cells transplanted into adult patients with acquired aplastic anemia: multivariate and propensity score-matched analysis. (21220035)
2011
24
Hematopoietic stem cell transplantation rates and long-term survival in acute myeloid and lymphoblastic leukemia: real-world population-based data from the Swedish Acute Leukemia Registry 1997-2006. (21387283)
2011
25
Clinical characteristics of Stenotrophomonas maltophilia infection in hematopoietic stem cell transplantation recipients: a single center experience. (20425134)
2010
26
Influence of glutathione S-transferase A1, P1, M1, T1 polymorphisms on oral busulfan pharmacokinetics in children with congenital hemoglobinopathies undergoing hematopoietic stem cell transplantation. (20672371)
2010
27
Early stop polymorphism in human DECTIN-1 is associated with increased candida colonization in hematopoietic stem cell transplant recipients. (19614557)
2009
28
KIR genes and KIR ligands affect occurrence of acute GVHD after unrelated, 12/12 HLA matched, hematopoietic stem cell transplantation. (19169284)
2009
29
Achievement of complete remission of refractory hairy cell leukemia by rituximab progressing after allogeneic hematopoietic stem cell transplantation. (19330554)
2009
30
Low serum levels of total rabbit-IgG is associated with acute graft-versus-host disease after unrelated donor hematopoietic stem cell transplantation: results from a prospective study. (19589490)
2009
31
Clinical significance of serum hepcidin levels on early infectious complications in allogeneic hematopoietic stem cell transplantation. (19589485)
2009
32
An unusual CD56(bright) CD16(low) NK cell subset dominates the early posttransplant period following HLA-matched hematopoietic stem cell transplantation. (18641363)
2008
33
Technology Insight: hematopoietic stem cell transplantation for systemic rheumatic disease. (18285764)
2008
34
Airway evaluation and management in 7 children with malignant infantile osteopetrosis before hematopoietic stem cell transplantation. (18376286)
2008
35
Increased incidence of cytomegalovirus retinitis after allogeneic hematopoietic stem cell transplantation. (17220797)
2007
36
C reactive protein and procalcitonin levels for the diagnosis of invasive bacterial infections in allogenic hematopoietic stem cell transplantation recipients]. (17989854)
2007
37
No influence of V617F mutation in JAK2 on outcome after allogeneic hematopoietic stem cell transplantation (HSCT) for myelofibrosis. (17162218)
2006
38
Neonatal hematopoietic stem cell transplantation cures oc/oc mice from osteopetrosis. (16459192)
2006
39
A pilot study of nonmyeloablative allogeneic hematopoietic stem cell transplant for advanced systemic mastocytosis. (16400343)
2006
40
Is combination antifungal therapy for invasive aspergillosis a necessity in hematopoietic stem-cell transplant recipients? (16804386)
2006
41
Surgery and treatment with high-dose liposomal amphotericin B for eradication of craniofacial zygomycosis in a patient with Hodgkin's disease who had undergone allogeneic hematopoietic stem cell transplantation. (15815047)
2005
42
Does hematopoietic stem cell transplantation improve patient outcome in juvenile myelomonocytic leukemia? (16264985)
2005
43
Simultaneous reconstitution of multiple cytomegalovirus-specific CD8+ cell populations with divergent functionality in hematopoietic stem-cell transplant recipients. (15717275)
2005
44
Identification of two new HLA-A*1101-restricted tax epitopes recognized by cytotoxic T lymphocytes in an adult T-cell leukemia patient after hematopoietic stem cell transplantation. (16014972)
2005
45
Hematopoietic stem cell transplantation (HSCT) in children with juvenile myelomonocytic leukemia (JMML): results of the EWOG-MDS/EBMT trial. (15353481)
2005
46
Intestinal cryptosporidiosis mimicking acute graft-versus-host disease following matched unrelated hematopoietic stem cell transplantation. (15167618)
2004
47
Polymorphisms within the genes encoding TNF-alpha and TNF-beta associate with the incidence of post-transplant complications in recipients of allogeneic hematopoietic stem cell transplants. (15467488)
2004
48
Engraftment syndrome after autologous hematopoietic stem cell transplant supported by granulocyte-colony-stimulating factor (G-CSF) versus granulocyte-macrophage colony-stimulating factor (GM-CSF). (12621492)
2003
49
Hematopoietic stem cell transplantation with conditioning regimens containing melphalan in pediatric patients with acute lymphoblastic leukemia]. (12229121)
2002
50
Role of tumor necrosis factor-alpha inhibition with inflixiMAB in cancer therapy and hematopoietic stem cell transplantation. (11085458)
2000

Variations for Hematopoietic Stem Cell Transplantation

About this section

Expression for genes affiliated with Hematopoietic Stem Cell Transplantation

About this section
Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Hematopoietic Stem Cell Transplantation

Search GEO for disease gene expression data for Hematopoietic Stem Cell Transplantation.

Pathways for genes affiliated with Hematopoietic Stem Cell Transplantation

About this section
Sources:
51PathCards, 56Reactome, 31KEGG, 39NCBI BioSystems Database, 54QIAGEN, 61Thomson Reuters
See all sources

Pathways related to Hematopoietic Stem Cell Transplantation according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
7.9KIR2DS3, KIR2DS5, KIR2DL3, KIR2DL2, KIR2DL1, KIR3DS1
27.5KIR2DS1, KIR2DS5, KIR2DL1, KIR3DL1, KIR2DL2, KIR2DL3
3
Show member pathways
7.5KIR2DS5, KIR2DS1, KIR2DL3, KIR2DL2, KIR2DS3, KIR2DL1
4
Show member pathways
7.2KIR2DS5, KIR2DL1, KIR3DL1, KIR2DL5A, KIR2DL4, KIR2DL2
5
Show member pathways
Immune response CD16 signaling in NK cells61
7.2KIR3DL1, KIR2DL5A, KIR2DL4, KIR2DL2, KIR2DL3, KIR2DS3

Compounds for genes affiliated with Hematopoietic Stem Cell Transplantation

About this section

GO Terms for genes affiliated with Hematopoietic Stem Cell Transplantation

About this section
Sources:
17Gene Ontology
See all sources

Cellular components related to Hematopoietic Stem Cell Transplantation according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1integral component of plasma membraneGO:0058877.3KIR3DS1, TNFRSF4, KIR2DS5, KIR2DS3, KIR2DL3, KIR2DL4
2plasma membraneGO:0058867.2KIR2DS1, KIR2DL3, KIR2DL2, KIR2DL4, KIR2DL5A, KIR3DL1

Biological processes related to Hematopoietic Stem Cell Transplantation according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cellular defense responseGO:0069689.1TNFRSF4, KIR2DS3, KIR2DL4
2signal transductionGO:0071658.3KIR3DS1, KIR3DL1, KIR2DL4, KIR2DS1, KIR2DS5
3regulation of immune responseGO:0507768.3KIR2DL1, KIR3DL1, KIR2DL4, KIR2DL2, KIR2DL3, KIR2DS1
4immune responseGO:0069557.5TNFRSF4, KIR2DS5, KIR2DS1, KIR2DL3, KIR3DL1, KIR2DL1

Molecular functions related to Hematopoietic Stem Cell Transplantation according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1transmembrane signaling receptor activityGO:0048889.6KIR2DL4, KIR2DS1

Products for genes affiliated with Hematopoietic Stem Cell Transplantation

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Hematopoietic Stem Cell Transplantation

About this section
4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet