Aliases & Classifications for Hemiplegia

MalaCards integrated aliases for Hemiplegia:

Name: Hemiplegia 12 72 49 28 41 14
Postnatal Infantile Hemiplegia 12
Hemiplegia, Infantile 69
Infantile Hemiplegia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10969
ICD9CM 34 343.4
MeSH 41 D006429
ICD10 32 G81 G81.9
UMLS 69 C0392550

Summaries for Hemiplegia

MalaCards based summary : Hemiplegia, also known as postnatal infantile hemiplegia, is related to familial porencephaly and porencephaly. An important gene associated with Hemiplegia is ATP1A3 (ATPase Na+/K+ Transporting Subunit Alpha 3), and among its related pathways/superpathways are Integrin Pathway and Aldosterone synthesis and secretion. The drugs Acetylcholine and abobotulinumtoxinA have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and bone, and related phenotype is behavior/neurological.

Wikipedia : 72 Hemiparesis, or unilateral paresis, is weakness of one entire side of the body (hemi- means \"half\").... more...

Related Diseases for Hemiplegia

Diseases related to Hemiplegia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 184)
# Related Disease Score Top Affiliating Genes
1 familial porencephaly 32.4 COL4A1 COL4A2
2 porencephaly 32.4 COL4A1 COL4A2
3 episodic ataxia 32.2 ATP1A2 CACNA1A SLC1A3
4 episodic ataxia, type 6 31.7 CACNA1A SLC1A3
5 alternating hemiplegia of childhood 31.2 ADCY5 ATP1A2 ATP1A3 CACNA1A CALCA SLC1A3
6 familial hemiplegic migraine 30.8 ATP1A2 ATP1A3 CACNA1A CALCA SCN1A
7 hemiplegic migraine 30.4 ATP1A2 ATP1A3 CACNA1A CALCA SCN1A SLC2A1
8 headache 28.3 ATP1A2 CACNA1A CALCA SCN1A TAC1
9 migraine with or without aura 1 28.2 ATP1A2 ATP1A3 CACNA1A CALCA SCN1A SLC1A3
10 spastic hemiplegia 12.5
11 alternating hemiplegia of childhood 2 12.2
12 alternating hemiplegia of childhood 1 12.2
13 idiopathic hemiconvulsion-hemiplegia syndrome 12.1
14 hemiplegia alterans 12.1
15 benign nocturnal alternating hemiplegia of childhood 12.0
16 epileptic hemiplegia 12.0
17 porencephaly 1 11.6
18 moyamoya disease 1 11.1
19 medial medullary syndrome 11.1
20 porencephaly 2 11.0
21 brown-sequard syndrome 11.0
22 moyamoya disease 2 10.8
23 moyamoya disease 5 10.8
24 moyamoya disease 6 with achalasia 10.8
25 spasticity 10.6
26 anosognosia 10.4
27 epilepsy 10.4
28 cerebritis 10.3
29 corneal dystrophy, posterior polymorphous, 3 10.2 COL4A1 COL4A2
30 laryngitis 10.2
31 myoclonic astatic epilepsy 10.1 SCN1A SLC2A1
32 episodic pain syndrome, familial, 1 10.1
33 herpes zoster 10.1
34 herpes zoster ophthalmicus 10.1
35 aceruloplasminemia 10.1 ATP1A3 CACNA1A SLC2A1
36 cluster headache 10.0 CACNA1A CALCA
37 cerebral arterial disease 10.0 ACTA2 RNF213
38 familial or sporadic hemiplegic migraine 10.0 ATP1A2 CACNA1A SCN1A
39 cerebral palsy 10.0
40 sporadic hemiplegic migraine 10.0 ATP1A2 CACNA1A SCN1A
41 migraine without aura 10.0 ATP1A2 CACNA1A SCN1A
42 osteitis fibrosa 10.0 BGLAP CALCA
43 migraine with aura 10.0 ATP1A2 CACNA1A SCN1A
44 visual epilepsy 10.0 ATP1A3 SCN1A SLC2A1
45 seizure disorder 10.0 ATP1A3 SCN1A SLC2A1
46 burn scar 10.0 CALCA TAC1
47 osteoporosis, juvenile 9.9 BGLAP CALCA
48 dystonia 9.9
49 vasomotor rhinitis 9.9 CALCA TAC1
50 stroke, ischemic 9.9

Graphical network of the top 20 diseases related to Hemiplegia:



Diseases related to Hemiplegia

Symptoms & Phenotypes for Hemiplegia

UMLS symptoms related to Hemiplegia:


hemiplegia

MGI Mouse Phenotypes related to Hemiplegia:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.32 ADCY5 ATP1A2 ATP1A3 CACNA1A COL4A1 RNF213

Drugs & Therapeutics for Hemiplegia

Drugs for Hemiplegia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 65)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcholine Approved Phase 4,Phase 3 51-84-3 187
2 abobotulinumtoxinA Phase 4,Phase 3
3 Botulinum Toxins Phase 4,Phase 3
4 Botulinum Toxins, Type A Phase 4,Phase 3
5 Cholinergic Agents Phase 4,Phase 3
6 Neuromuscular Agents Phase 4,Phase 3
7 Neurotransmitter Agents Phase 4,Phase 3,Phase 1
8 onabotulinumtoxinA Phase 4,Phase 3
9 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
10 Gastrodia Nutraceutical Phase 4
11
Benzocaine Approved, Investigational Phase 3 1994-09-7, 94-09-7 2337
12 tannic acid Approved, Nutraceutical Phase 3
13
Menthol Approved Phase 2,Phase 1 2216-51-5 16666
14
Sodium oxybate Approved Phase 1, Phase 2 502-85-2 5360545
15
Lidocaine Approved, Vet_approved Phase 2 137-58-6 3676
16
Triamcinolone Approved, Vet_approved Phase 2 124-94-7 31307
17
Glycerol Approved, Investigational Phase 2 56-81-5 753
18 Carbon fiber Phase 1, Phase 2
19 Adjuvants, Anesthesia Phase 1, Phase 2
20 Anesthetics Phase 1, Phase 2
21 Anesthetics, General Phase 1, Phase 2
22 Anesthetics, Intravenous Phase 1, Phase 2
23 Central Nervous System Depressants Phase 1, Phase 2
24 Anesthetics, Local Phase 2
25 Anti-Arrhythmia Agents Phase 2
26 Diuretics, Potassium Sparing Phase 2
27 Sodium Channel Blockers Phase 2
28 Anti-Inflammatory Agents Phase 2
29 glucocorticoids Phase 2
30 Hormone Antagonists Phase 2
31 Hormones Phase 2
32 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2
33 Immunosuppressive Agents Phase 2
34 triamcinolone acetonide Phase 2
35 Triamcinolone diacetate Phase 2
36 Triamcinolone hexacetonide Phase 2
37 Protective Agents Phase 2
38
Dopamine Approved Phase 1 51-61-6, 62-31-7 681
39
Methamphetamine Approved, Illicit Phase 1 537-46-2 10836
40 Adrenergic Agents Phase 1
41 Autonomic Agents Phase 1
42 Central Nervous System Stimulants Phase 1
43 Dopamine Agents Phase 1
44 Dopamine Uptake Inhibitors Phase 1
45 Neurotransmitter Uptake Inhibitors Phase 1
46
Fluoxetine Approved, Vet_approved 54910-89-3 3386
47
Flumazenil Approved 78755-81-4 3373
48
gamma-Aminobutyric acid Approved, Investigational 56-12-2 119
49 Antibodies
50 calcitonin

Interventional clinical trials:

(show top 50) (show all 205)

# Name Status NCT ID Phase Drugs
1 Functional Electrical Stimulation (FES) Assisted Walking: Enhancement of Walking Function After Stroke Unknown status NCT00552916 Phase 4
2 Gastrodin Prevents Cognitive Decline Related to Cardiopulmonary Bypass Unknown status NCT00297245 Phase 4 cognitive function
3 A Randomized Double Blind Placebo Control Study of Huang-Chi-Wu-Wu- Tang in Patients With Intracranial Arterial Stenosis Unknown status NCT01553643 Phase 4 Chinese Herb Huang-Chi-Wu-Wu-Tang;placebo
4 The Efficacy and Safety of MEDITOXIN® in Children With Cerebral Palsy Unknown status NCT01256021 Phase 4 Botulinum Toxin Type A
5 Τhe Effectiveness of Hydrotherapy Exercises on the Rehabilitation of Hemiplegic Patients Completed NCT01460277 Phase 4
6 The Effect of a Self-rehabilitation Program in Addition to Usual Treatment for Spasticity on Impairment and Activity Limitation in Patients With Spastic Hemiparesis Following Stroke Recruiting NCT02944929 Phase 4
7 Study to Evaluate Effects of DYSPORT® Injected in Lower and Upper Limb Combined With Guided Self-Rehabilitation Contract (GSC) Active, not recruiting NCT02969356 Phase 4 AbobotulinumtoxinA (Dysport®)
8 Randomised, Evaluation-blinded, Crossover, Controlled Study Assessing Dynamic Hand Splinting in Adults With Post-stroke Hemiplegia (Orthox) Not yet recruiting NCT02888548 Phase 4
9 HEMITOX : Effect of Botulinum Toxin Injections on Motor and Functional Ability of Upper Limb in Adults at Earlier Phases of Spastic Hemiplegia After Stroke Unknown status NCT00276185 Phase 3 Time delay treatment of botulinum toxin
10 Mental Practice Efficacy in Stroke-Induced Hemiparesis Unknown status NCT01026896 Phase 2, Phase 3
11 Modulation of Brain Plasticity After Perinatal Stroke Unknown status NCT01189058 Phase 2, Phase 3
12 MEOPA to Improve Physical Therapy Results After Multilevel Surgery Completed NCT00632528 Phase 3 MEOPA;Medicinal air
13 Assisted Movement Neuro-rehabilitation: VA Multi-site Clinical Trial Completed NCT00223808 Phase 3
14 Static and Dynamic Postural Stability in Cerebral Palsy Children Completed NCT01799304 Phase 3
15 Phase III Clinical Trial of "Botulax®" to Treat Children With Cerebral Palsy Completed NCT01787344 Phase 3 Botulinum Toxin Type A(Botox®);Botulinum toxin type A(Botulax®)
16 Home Based Adaptive Arm Training for Children Recruiting NCT02751502 Phase 3
17 Ventilatory Muscle Training in Stroke Recruiting NCT02828943 Phase 3
18 Stimulation for Perinatal Stroke Optimizing Recovery Trajectories Recruiting NCT03216837 Phase 2, Phase 3
19 Effects of the Quantity of Repetitive Transcranial Magnetic Stimulation(rTMS) on the Recovery After Stroke Terminated NCT01311271 Phase 2, Phase 3
20 Bimanual Training in Children With Hemiplegia Unknown status NCT01413594 Phase 1, Phase 2
21 Bimanual Training in Children With Hemiplegia With Lower Limb and Postural Stimulation (HABIT & Leg) Unknown status NCT01700777 Phase 1, Phase 2
22 Rehabilitation of Early Stroke Patients Using an AFO: an RCT Unknown status NCT01006772 Phase 1, Phase 2
23 Use of Tendon Vibration and Mirror for the Improvement of Upper Limb Function and Pain Reduction Unknown status NCT01010607 Phase 1, Phase 2
24 The Middle East "Stepping Forward" Project (MESF) Unknown status NCT01466296 Phase 2
25 mCIMT and Eye Patching for Neglect Rehabilitation Post Stroke: A Longitudinal Study of Separate and Combined Effects Unknown status NCT00253825 Phase 1, Phase 2
26 Sodium Oxybate in Patients With Alternating Hemiplegia of Childhood (AHC-SO) Completed NCT00931164 Phase 1, Phase 2 Sodium Oxybate
27 Study of HC-58 in Upper Limb Hemiplegic Patients After Stroke Completed NCT01623622 Phase 2 HC-58;Placebo
28 Low Intensity Physical Activity Leads to Improvement in Brachial-ankle Pulse Wave Velocity of Hemiplegics Completed NCT01569386 Phase 2
29 Training the Arm and Hand After Stroke Using Auditory Rhythm Cues Completed NCT00523523 Phase 1, Phase 2
30 Functional Electrical Stimulation for Footdrop in Hemiparesis Completed NCT00148343 Phase 2
31 Post Stroke Hand Functions: Bilateral Movements and Electrical Stimulation Treatments Completed NCT00369668 Phase 2
32 Contrastim Stroke Trial Completed NCT01049802 Phase 1, Phase 2
33 Treatments for Recovery of Hand Function in Acute Stroke Survivors Completed NCT00565045 Phase 1, Phase 2
34 FNS and Weight Support Treadmill Training for Gait Component Restoration Completed NCT00011596 Phase 2
35 The Influence of MCIMT (Modified Constrained Induced Movement Therapy), Bilateral Intensive Treatment, and NDT Approach on the UL Function in Children With Hemiplegic Cerebral Palsy Completed NCT00619853 Phase 2
36 SSNB in Hemiplegic Shoulder Pain Completed NCT00732589 Phase 2 1% xylocaine
37 Robot Assisted Upper Limb Neuro-Rehabilitation Completed NCT00011583 Phase 2
38 Subacromial Corticosteroid Injection for Hemiplegic Shoulder Pain Completed NCT00597766 Phase 2 Lidocaine;Triamcinolone + Lidocaine;Triamcinolone + Lidocaine;Triamcinolone + Lidocaine
39 Video-Based Functional Performance and Assessment Following Stroke Completed NCT00013494 Phase 2
40 Percutaneous Recanalization in Ischemic Stroke Management (PRIISM): A Feasibility Clinical Study Completed NCT00810095 Phase 2
41 E-Rehabilitation: Aerobic Resistance Training for Stroke Survivors Recruiting NCT02938000 Phase 1, Phase 2
42 Effects of Upper Extremity Rehabilitation Using Smart Glove in Stroke Patients Recruiting NCT02592759 Phase 2
43 Pilot Study, Comparative, Single-center, Randomized, Crossover, Double-blind, Against Placebo, Testing the Effectiveness of Triheptanoin Oil in Alternating Hemiplegia of Childhood Active, not recruiting NCT02408354 Phase 2 Triheptanoin;Placebo
44 Passive Mobilisation of Region of Shoulder Joints for Hemiplegic Patient Not yet recruiting NCT02904148 Phase 2
45 Constraint-induced Movement Therapy (CIMT) and Bimanual Training (HABIT) in Children With Hemiplegic Cerebral Palsy Unknown status NCT00305006 Phase 1
46 Pediatric Hemiplegia: Synergistic Treatment Using rTMS and CIT Completed NCT01104064 Phase 1
47 Foot Posture in People With Paralysis on One Side After Stroke Completed NCT00308035 Phase 1
48 Optimizing Hand Rehabilitation Post-Stroke Using Interactive Virtual Environments Completed NCT01072461 Phase 1
49 An Exploratory Clinical Study on a Variable Speed and Sensing Treadmill System (VASST) for Hemiparetic Gait Rehabilitation Completed NCT01811680 Phase 1
50 Home Exercise With Wearable Sensors Not yet recruiting NCT03416842 Phase 1

Search NIH Clinical Center for Hemiplegia

Cochrane evidence based reviews: hemiplegia

Genetic Tests for Hemiplegia

Genetic tests related to Hemiplegia:

# Genetic test Affiliating Genes
1 Hemiplegia 28

Anatomical Context for Hemiplegia

MalaCards organs/tissues related to Hemiplegia:

38
Brain, Testes, Bone, Eye, Cortex, Skin, Spinal Cord

Publications for Hemiplegia

Articles related to Hemiplegia:

(show top 50) (show all 816)
# Title Authors Year
1
Long-term follow up of an adult with alternating hemiplegia of childhood and a p.Gly755Ser mutation in the ATP1A3 gene. ( 29269014 )
2018
2
Different impact of prism adaptation rehabilitation in spatial neglect and anosognosia for hemiplegia. ( 29357315 )
2018
3
Development of an item list to assess bilateral upper extremity function of stroke patients with hemiplegia. ( 29400669 )
2018
4
Rewiring to Regain Function in Patients with Spastic Hemiplegia. ( 29261362 )
2018
5
Clinical aspects, neuroimaging, and electroencephalography of 35 cases of hemiconvulsion-hemiplegia syndrome. ( 29414550 )
2018
6
Rehabilitation for hemiplegia using an upper limb training system based on a force direction. ( 28813875 )
2017
7
Kinect-based gait analyses of patients with Parkinson's disease, patients with stroke with hemiplegia, and healthy adults. ( 28266138 )
2017
8
Alternating Hemiplegia and Epilepsia Partialis Continua: A new phenotype for a novel compound TBC1D24 mutation. ( 28292732 )
2017
9
Alternating hemiplegia of childhood and a pathogenic variant of ATP1A3: a case report and pathophysiological considerations. ( 28637637 )
2017
10
Hemiplegia as a presentation of HIV infection in children: A report of 3 cases. ( 29302563 )
2017
11
Dengue fever triggering hemiconvulsion hemiplegia epilepsy in a child. ( 28488637 )
2017
12
A randomized, controlled, double-blind, crossover trial of triheptanoin in alternating hemiplegia of childhood. ( 28969699 )
2017
13
Motor function domains in alternating hemiplegia of childhood. ( 28543714 )
2017
14
More Than a Decade of Misdiagnosis of Alternating Hemiplegia of Childhood with Catastrophic Outcome. ( 28900444 )
2017
15
Ocular Motor Function in Children with Spastic Hemiplegia Evaluated by the Ocular Motor Score. ( 28771056 )
2017
16
Challenges describing motor profiles in alternating hemiplegia of childhood. ( 28556907 )
2017
17
Alternating Hemiplegia of Childhood: Pharmacological treatment of 30 Italian patients. ( 28249736 )
2017
18
Effect of sensory and motor connectivity on hand function in pediatric hemiplegia. ( 29034483 )
2017
19
An Infant With Epilepsy and Recurrent Hemiplegia due to Compound Heterozygous Variants in ATP1A2. ( 28811059 )
2017
20
Exercise using a robotic knee orthosis in stroke patients with hemiplegia. ( 29200624 )
2017
21
Altered effective connectivity of resting state networks by acupuncture stimulation in stroke patients with left hemiplegia: A multivariate granger analysis. ( 29382021 )
2017
22
A Randomized Controlled Study: Effectiveness of Functional Electrical Stimulation on Wrist and Finger Flexor Spasticity in Hemiplegia. ( 28462794 )
2017
23
Combined therapy using botulinum toxin A and single-joint hybrid assistive limb for upper-limb disability due to spastic hemiplegia. ( 28131185 )
2017
24
Diagnosis and Treatment of Alternating Hemiplegia of Childhood. ( 28337648 )
2017
25
ATP1A3 mutant patient with alternating hemiplegia of childhood and brain spectroscopic abnormalities. ( 28716275 )
2017
26
Intermittent Hemiplegia in a Boy with Primary Moyamoya Disease: A Case Report from Iran. ( 28698731 )
2017
27
Modulating anosognosia for hemiplegia: The role of dangerous actions in emergent awareness. ( 28501758 )
2017
28
Three consecutive neurotomies in one patient for the treatment of spastic hemiplegia: Spinal, median, and foot toes common flexor. ( 29184718 )
2017
29
Guillain-BarrAc Syndrome: A Variant Consisting of Facial Diplegia and Paresthesia with Left Facial Hemiplegia Associated with Antibodies to Galactocerebroside and Phosphatidic Acid. ( 28966341 )
2017
30
REACH: study protocol of a randomised trial of rehabilitation very early in congenital hemiplegia. ( 28928195 )
2017
31
Effects of weight training time on bone mineral density of patients with secondary osteoporosis after hemiplegia. ( 28450926 )
2017
32
Topiramate Therapy in Alternating Hemiplegia of Childhood. ( 28502069 )
2017
33
Hemiconvulsion-hemiplegia-epilepsy syndrome in a child with pre-existing cerebral pathology. ( 28652222 )
2017
34
Recurrent Focal Seizures and Transient Hemiparesis: Think About Alternating Hemiplegia of Childhood. ( 29395725 )
2017
35
Action observation facilitates motor cortical activity in patients with stroke and hemiplegia. ( 29031830 )
2017
36
Dynamic paraspinal muscle impingement causing acute hemiplegia after C1 posterior arch laminectomy: A case report. ( 29390372 )
2017
37
Alternating Hemiplegia of Childhood with Novel Features. ( 28138908 )
2017
38
Diagnostic Challenge of Diffusion Tensor Imaging in a Patient With Hemiplegia After Traumatic Brain Injury. ( 28289648 )
2017
39
Muscle Strength and Poststroke Hemiplegia: A Systematic Review of Muscle Strength Assessment and Muscle Strength Impairment. ( 27372002 )
2016
40
Hemiplegia following multiple bee sting. ( 27727866 )
2016
41
CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 13-2016. A 49-Year-Old Woman with Sudden Hemiplegia and Aphasia during a Transatlantic Flight. ( 27119240 )
2016
42
Comparison of the Effect of Lateral and Backward Walking Training on Walking Function in Patients with Poststroke Hemiplegia: A Pilot Randomized Controlled Trial. ( 27323323 )
2016
43
Treatment with Oral ATP decreases alternating hemiplegia of childhood with de novo ATP1A3 Mutation. ( 27146299 )
2016
44
Does unilateral single-event multilevel surgery improve gait in children with spastic hemiplegia? A retrospective analysis of a long-term follow-up. ( 27907872 )
2016
45
Feasibility of Using an Arm Weight-Supported Training System to Improve Hand Function Skills in Children With Hemiplegia. ( 27767944 )
2016
46
A predominantly left-sided skin reaction to pristinamycin in a patient with right hemiplegia. ( 27051837 )
2016
47
Effects of shoulder reaching exercise on the balance of patients with hemiplegia after stroke. ( 27512286 )
2016
48
The Influence of Rocker Bar Ankle Foot Orthosis on Gait in Patients with Chronic Hemiplegia. ( 27265095 )
2016
49
Hemiconvulsion-hemiplegia syndrome. ( 27625282 )
2016
50
Acute mental change and hemiplegia after autologous fat injection. ( 27352047 )
2016

Variations for Hemiplegia

ClinVar genetic disease variations for Hemiplegia:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 ATP1A3 NM_152296.4(ATP1A3): c.2839G> A (p.Gly947Arg) single nucleotide variant Pathogenic rs398122887 GRCh37 Chromosome 19, 42471896: 42471896

Expression for Hemiplegia

Search GEO for disease gene expression data for Hemiplegia.

Pathways for Hemiplegia

Pathways related to Hemiplegia according to GeneCards Suite gene sharing:

(show all 15)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.08 ACTA2 ADCY5 CACNA1A COL4A1 COL4A2
2
Show member pathways
12.5 ADCY5 ATP1A2 ATP1A3 SLC2A1
3
Show member pathways
12.48 ADCY5 CACNA1A SCN1A SLC1A3
4
Show member pathways
12.4 ACTA2 ADCY5 ATP1A2 ATP1A3
5
Show member pathways
12.14 ACTA2 ADCY5 COL4A1 COL4A2
6
Show member pathways
12.05 ACTA2 ADCY5 CACNA1A CALCA
7
Show member pathways
11.94 ACTA2 ADCY5 COL4A1 COL4A2
8
Show member pathways
11.89 ADCY5 ATP1A2 ATP1A3
9 11.87 ATP1A3 SLC1A3 TAC1
10
Show member pathways
11.69 ACTA2 ADCY5 ATP1A2 ATP1A3 SCN1A TAC1
11 11.64 ATP1A2 ATP1A3 SLC2A1
12
Show member pathways
11.6 ATP1A2 CACNA1A SLC1A3
13 11.31 ADCY5 ATP1A2 ATP1A3
14 11.11 ADCY5 ATP1A2 ATP1A3 SLC2A1
15 10.79 ATP1A2 ATP1A3

GO Terms for Hemiplegia

Cellular components related to Hemiplegia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 axon GO:0030424 9.67 ATP1A3 CALCA SCN1A TAC1
2 sarcolemma GO:0042383 9.5 ATP1A2 ATP1A3 SLC2A1
3 sodium:potassium-exchanging ATPase complex GO:0005890 9.26 ATP1A2 ATP1A3
4 collagen type IV trimer GO:0005587 9.16 COL4A1 COL4A2
5 intercalated disc GO:0014704 9.13 ATP1A2 SCN1A SLC2A1
6 neuronal cell body GO:0043025 9.1 ATP1A3 CACNA1A CALCA SCN1A SLC1A3 TAC1

Biological processes related to Hemiplegia according to GeneCards Suite gene sharing:

(show all 22)
# Name GO ID Score Top Affiliating Genes
1 ion transport GO:0006811 9.95 ATP1A2 ATP1A3 CACNA1A SCN1A SLC1A3
2 aging GO:0007568 9.77 BGLAP CALCA COL4A2
3 sodium ion transport GO:0006814 9.74 ATP1A2 ATP1A3 SCN1A
4 ion transmembrane transport GO:0034220 9.73 ATP1A2 ATP1A3 CACNA1A SCN1A
5 adult walking behavior GO:0007628 9.61 CACNA1A SCN1A
6 membrane depolarization during action potential GO:0086010 9.59 CACNA1A SCN1A
7 cellular response to amyloid-beta GO:1904646 9.58 ATP1A3 CACNA1A
8 potassium ion import GO:0010107 9.58 ATP1A2 ATP1A3
9 regulation of blood pressure GO:0008217 9.58 ATP1A2 CALCA TAC1
10 positive regulation of ossification GO:0045778 9.56 CALCA TAC1
11 cell communication by electrical coupling involved in cardiac conduction GO:0086064 9.54 ATP1A2 ATP1A3
12 cellular response to steroid hormone stimulus GO:0071383 9.52 ATP1A2 ATP1A3
13 cellular sodium ion homeostasis GO:0006883 9.51 ATP1A2 ATP1A3
14 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.49 ATP1A2 ATP1A3
15 collagen-activated tyrosine kinase receptor signaling pathway GO:0038063 9.48 COL4A1 COL4A2
16 cellular potassium ion homeostasis GO:0030007 9.46 ATP1A2 ATP1A3
17 sodium ion export across plasma membrane GO:0036376 9.37 ATP1A2 ATP1A3
18 neuromuscular process controlling balance GO:0050885 9.33 ADCY5 CACNA1A SLC1A3
19 response to glycoside GO:1903416 9.32 ATP1A2 ATP1A3
20 neurotransmitter uptake GO:0001504 9.26 ATP1A2 SLC1A3
21 positive regulation of cytosolic calcium ion concentration GO:0007204 9.26 ADCY5 CACNA1A CALCA TAC1
22 response to pain GO:0048265 8.8 CACNA1A CALCA TAC1

Molecular functions related to Hemiplegia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 8.96 ATP1A2 ATP1A3
2 steroid hormone binding GO:1990239 8.62 ATP1A2 ATP1A3

Sources for Hemiplegia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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