Aliases & Classifications for Hemiplegia

MalaCards integrated aliases for Hemiplegia:

Name: Hemiplegia 12 50 29 42 14
Postnatal Infantile Hemiplegia 12
Hemiplegia, Infantile 69
Infantile Hemiplegia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:10969
ICD9CM 35 343.4
MeSH 42 D006429
ICD10 33 G81 G81.9
UMLS 69 C0392550

Summaries for Hemiplegia

MalaCards based summary : Hemiplegia, also known as postnatal infantile hemiplegia, is related to alternating hemiplegia of childhood and aneurysm. An important gene associated with Hemiplegia is ATP1A3 (ATPase Na+/K+ Transporting Subunit Alpha 3), and among its related pathways/superpathways are Circadian entrainment and Pathways in cancer. The drugs Acetylcholine and abobotulinumtoxinA have been mentioned in the context of this disorder. Affiliated tissues include brain, testes and bone, and related phenotype is behavior/neurological.

Related Diseases for Hemiplegia

Diseases related to Hemiplegia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 165)
id Related Disease Score Top Affiliating Genes
1 alternating hemiplegia of childhood 30.2 ADCY5 ATP1A2 ATP1A3 CACNA1A CALCA SLC1A3
2 aneurysm 29.6 ATP1A2 CACNA1A SCN1A
3 spastic hemiplegia 12.4
4 alternating hemiplegia of childhood 2 12.1
5 hemiplegia alterans 11.9
6 benign nocturnal alternating hemiplegia of childhood 11.8
7 epileptic hemiplegia 11.8
8 atp1a2-related alternating hemiplegia of childhood 11.8
9 atp1a3-related alternating hemiplegia of childhood 11.8
10 idiopathic hemiconvulsion-hemiplegia syndrome 11.8
11 porencephaly 1 11.3
12 episodic ataxia 11.2
13 porencephaly 11.2
14 familial porencephaly 11.1
15 hemiplegic migraine 11.1
16 familial hemiplegic migraine 11.0
17 moyamoya disease 11.0
18 medial medullary syndrome 10.9
19 porencephaly 2 10.9
20 brown-sequard syndrome 10.9
21 moyamoya disease 2 10.7
22 spastic cerebral palsy 10.7
23 moyamoya 6 with achalasia 10.7
24 episodic ataxia, type 6 10.7
25 moyamoya disease 5 10.7
26 familial stomach cancer 10.6 COL4A1 COL4A2
27 aplasia of lacrimal and salivary glands 10.5 CACNA1A SLC1A3
28 spasticity 10.5
29 primary pigmented nodular adrenocortical disease 10.5 COL4A1 COL4A2
30 corneal dystrophy, fuchs endothelial, 6 10.4 COL4A1 COL4A2
31 retinal arteries, tortuosity of 10.4 COL4A1 COL4A2
32 cone-rod dystrophy 5 10.4 CACNA1A SLC2A1
33 anosognosia 10.3
34 babesiosis 10.3 ATP1A2 CACNA1A SLC1A3
35 epilepsy 10.3
36 hyperphenylalaninemia, bh4-deficient, b 10.3 ATP1A3 SLC2A1
37 myoglobinuria dominant form 10.3 SCN1A SLC2A1
38 cerebritis 10.2
39 unverricht-lundborg syndrome 10.2 ACTA2 RNF213
40 coarse face hypotonia constipation 10.1 CACNA1A CALCA
41 myopathy-growth delay-intellectual disability-hypospadias syndrome 10.1 ATP1A2 CACNA1A SCN1A
42 laryngitis 10.1
43 mixed cell type adenoma of parathyroid 10.1 BGLAP CALCA
44 pelvic inflammatory disease 10.1 ATP1A2 CACNA1A SCN1A
45 xanthomatosis 10.1 BGLAP CALCA
46 glans penis cancer 10.0 ATP1A3 SCN1A SLC2A1
47 spinocerebellar degeneration 10.0 ATP1A3 SCN1A SLC2A1
48 herpes zoster 10.0
49 hypophosphatasia, adult 10.0 BGLAP CALCA
50 cartilage disease 10.0 CALCA TAC1

Graphical network of the top 20 diseases related to Hemiplegia:



Diseases related to Hemiplegia

Symptoms & Phenotypes for Hemiplegia

UMLS symptoms related to Hemiplegia:


hemiplegia

MGI Mouse Phenotypes related to Hemiplegia:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.32 ADCY5 ATP1A2 ATP1A3 CACNA1A COL4A1 RNF213

Drugs & Therapeutics for Hemiplegia

Drugs for Hemiplegia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 63)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcholine Approved Phase 4,Phase 3 51-84-3 187
2 abobotulinumtoxinA Phase 4,Phase 3
3 Botulinum Toxins Phase 4,Phase 3
4 Botulinum Toxins, Type A Phase 4,Phase 3
5 Cholinergic Agents Phase 4,Phase 3
6 Neuromuscular Agents Phase 4,Phase 3
7 Neurotransmitter Agents Phase 4,Phase 3,Phase 1
8 onabotulinumtoxinA Phase 4,Phase 3
9 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
10 Gastrodia Nutraceutical Phase 4
11
Benzocaine Approved Phase 3 1994-09-7, 94-09-7 2337
12 tannic acid Approved, Nutraceutical Phase 3
13
Menthol Approved Phase 2,Phase 1 2216-51-5 16666
14
Lidocaine Approved, Vet_approved Phase 2 137-58-6 3676
15
Triamcinolone Approved, Vet_approved Phase 2 124-94-7 31307
16
Sodium oxybate Approved Phase 1, Phase 2 502-85-2 5360545
17
Glycerol Approved, Investigational Phase 2 56-81-5 753
18 Carbon fiber Phase 1, Phase 2
19 Anesthetics Phase 2,Phase 1
20 Anesthetics, Local Phase 2
21 Anti-Arrhythmia Agents Phase 2
22 Anti-Inflammatory Agents Phase 2
23 Central Nervous System Depressants Phase 2,Phase 1
24 Diuretics, Potassium Sparing Phase 2
25 glucocorticoids Phase 2
26 Hormone Antagonists Phase 2
27 Hormones Phase 2
28 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2
29 Immunosuppressive Agents Phase 2
30 Sodium Channel Blockers Phase 2
31 triamcinolone acetonide Phase 2
32 Triamcinolone diacetate Phase 2
33 Triamcinolone hexacetonide Phase 2
34 Adjuvants, Anesthesia Phase 1, Phase 2
35 Anesthetics, General Phase 1, Phase 2
36 Anesthetics, Intravenous Phase 1, Phase 2
37 Protective Agents Phase 2
38
Dopamine Approved Phase 1 51-61-6, 62-31-7 681
39
Methamphetamine Approved, Illicit Phase 1 537-46-2 10836
40 Adrenergic Agents Phase 1
41 Autonomic Agents Phase 1
42 Central Nervous System Stimulants Phase 1
43 Dopamine Agents Phase 1
44 Dopamine Uptake Inhibitors Phase 1
45 Neurotransmitter Uptake Inhibitors Phase 1
46
Fluoxetine Approved, Vet_approved 54910-89-3 3386
47
Flumazenil Approved 78755-81-4 3373
48
gamma-Aminobutyric acid Investigational 56-12-2 119
49 Antibodies
50 calcitonin

Interventional clinical trials:

(show top 50) (show all 192)

id Name Status NCT ID Phase Drugs
1 Functional Electrical Stimulation (FES) Assisted Walking: Enhancement of Walking Function After Stroke Unknown status NCT00552916 Phase 4
2 Gastrodin Prevents Cognitive Decline Related to Cardiopulmonary Bypass Unknown status NCT00297245 Phase 4 cognitive function
3 A Randomized Double Blind Placebo Control Study of Huang-Chi-Wu-Wu- Tang in Patients With Intracranial Arterial Stenosis Unknown status NCT01553643 Phase 4 Chinese Herb Huang-Chi-Wu-Wu-Tang;placebo
4 The Efficacy and Safety of MEDITOXIN® in Children With Cerebral Palsy Unknown status NCT01256021 Phase 4 Botulinum Toxin Type A
5 Τhe Effectiveness of Hydrotherapy Exercises on the Rehabilitation of Hemiplegic Patients Completed NCT01460277 Phase 4
6 Randomised, Evaluation-blinded, Crossover, Controlled Study Assessing Dynamic Hand Splinting in Adults With Post-stroke Hemiplegia (Orthox) Recruiting NCT02888548 Phase 4
7 Study to Evaluate Effects of DYSPORT® Injected in Lower and Upper Limb Combined With Guided Self-Rehabilitation Contract (GSC) Recruiting NCT02969356 Phase 4 AbobotulinumtoxinA (Dysport®)
8 The Effect of a Self-rehabilitation Program in Addition to Usual Treatment for Spasticity on Impairment and Activity Limitation in Patients With Spastic Hemiparesis Following Stroke Not yet recruiting NCT02944929 Phase 4
9 HEMITOX : Effect of Botulinum Toxin Injections on Motor and Functional Ability of Upper Limb in Adults at Earlier Phases of Spastic Hemiplegia After Stroke Unknown status NCT00276185 Phase 3 Time delay treatment of botulinum toxin
10 Mental Practice Efficacy in Stroke-Induced Hemiparesis Unknown status NCT01026896 Phase 2, Phase 3
11 Modulation of Brain Plasticity After Perinatal Stroke Unknown status NCT01189058 Phase 2, Phase 3
12 MEOPA to Improve Physical Therapy Results After Multilevel Surgery Completed NCT00632528 Phase 3 MEOPA;Medicinal air
13 Assisted Movement Neuro-rehabilitation: VA Multi-site Clinical Trial Completed NCT00223808 Phase 3
14 Static and Dynamic Postural Stability in Cerebral Palsy Children Completed NCT01799304 Phase 3
15 Phase III Clinical Trial of "Botulax®" to Treat Children With Cerebral Palsy Completed NCT01787344 Phase 3 Botulinum Toxin Type A(Botox®);Botulinum toxin type A(Botulax®)
16 Ventilatory Muscle Training in Stroke Recruiting NCT02828943 Phase 3
17 Stimulation for Perinatal Stroke Optimizing Recovery Trajectories Recruiting NCT03216837 Phase 2, Phase 3
18 Home Based Adaptive Arm Training for Children Not yet recruiting NCT02751502 Phase 3
19 Effects of the Quantity of Repetitive Transcranial Magnetic Stimulation(rTMS) on the Recovery After Stroke Terminated NCT01311271 Phase 2, Phase 3
20 Bimanual Training in Children With Hemiplegia Unknown status NCT01413594 Phase 1, Phase 2
21 Bimanual Training in Children With Hemiplegia With Lower Limb and Postural Stimulation (HABIT & Leg) Unknown status NCT01700777 Phase 1, Phase 2
22 Rehabilitation of Early Stroke Patients Using an AFO: an RCT Unknown status NCT01006772 Phase 1, Phase 2
23 Use of Tendon Vibration and Mirror for the Improvement of Upper Limb Function and Pain Reduction Unknown status NCT01010607 Phase 1, Phase 2
24 The Middle East "Stepping Forward" Project (MESF) Unknown status NCT01466296 Phase 2
25 mCIMT and Eye Patching for Neglect Rehabilitation Post Stroke: A Longitudinal Study of Separate and Combined Effects Unknown status NCT00253825 Phase 1, Phase 2
26 Subacromial Corticosteroid Injection for Hemiplegic Shoulder Pain Unknown status NCT00597766 Phase 2 Lidocaine;Triamcinolone + Lidocaine;Triamcinolone + Lidocaine;Triamcinolone + Lidocaine
27 Sodium Oxybate in Patients With Alternating Hemiplegia of Childhood (AHC-SO) Completed NCT00931164 Phase 1, Phase 2 Sodium Oxybate
28 Study of HC-58 in Upper Limb Hemiplegic Patients After Stroke Completed NCT01623622 Phase 2 HC-58;Placebo
29 Electrical Stimulation for Recovery of Hand Function in Chronic Stroke Survivors Completed NCT00891319 Phase 2
30 Low Intensity Physical Activity Leads to Improvement in Brachial-ankle Pulse Wave Velocity of Hemiplegics Completed NCT01569386 Phase 2
31 Falls-based Training for Walking Post-Stroke Completed NCT02787759 Phase 2
32 Functional Electrical Stimulation for Footdrop in Hemiparesis Completed NCT00148343 Phase 2
33 Training the Arm and Hand After Stroke Using Auditory Rhythm Cues Completed NCT00523523 Phase 1, Phase 2
34 Post Stroke Hand Functions: Bilateral Movements and Electrical Stimulation Treatments Completed NCT00369668 Phase 2
35 Contrastim Stroke Trial Completed NCT01049802 Phase 1, Phase 2
36 Treatments for Recovery of Hand Function in Acute Stroke Survivors Completed NCT00565045 Phase 1, Phase 2
37 FNS and Weight Support Treadmill Training for Gait Component Restoration Completed NCT00011596 Phase 2
38 The Influence of MCIMT (Modified Constrained Induced Movement Therapy), Bilateral Intensive Treatment, and NDT Approach on the UL Function in Children With Hemiplegic Cerebral Palsy Completed NCT00619853 Phase 2
39 Robot Assisted Upper Limb Neuro-Rehabilitation Completed NCT00011583 Phase 2
40 SSNB in Hemiplegic Shoulder Pain Completed NCT00732589 Phase 2 1% xylocaine
41 Video-Based Functional Performance and Assessment Following Stroke Completed NCT00013494 Phase 2
42 Percutaneous Recanalization in Ischemic Stroke Management (PRIISM): A Feasibility Clinical Study Completed NCT00810095 Phase 2
43 Combined Constraint Therapy and Bimanual Therapy for Children With Unilateral Brain Injury Recruiting NCT02840643 Phase 1, Phase 2
44 E-Rehabilitation: Aerobic Resistance Training for Stroke Survivors Recruiting NCT02938000 Phase 1, Phase 2
45 Effects of Upper Extremity Rehabilitation Using Smart Glove in Stroke Patients Recruiting NCT02592759 Phase 2
46 Pilot Study, Comparative, Single-center, Randomized, Crossover, Double-blind, Against Placebo, Testing the Effectiveness of Triheptanoin Oil in Alternating Hemiplegia of Childhood Active, not recruiting NCT02408354 Phase 2 Triheptanoin;Placebo
47 Passive Mobilisation of Region of Shoulder Joints for Hemiplegic Patient Not yet recruiting NCT02904148 Phase 2
48 Constraint-induced Movement Therapy (CIMT) and Bimanual Training (HABIT) in Children With Hemiplegic Cerebral Palsy Unknown status NCT00305006 Phase 1
49 Functional Electrical Stimulation Mediated Neuroplasticity: Lower Extremity CCNMES in Stroke Unknown status NCT02199795 Phase 1
50 Pediatric Hemiplegia: Synergistic Treatment Using rTMS and CIT Completed NCT01104064 Phase 1

Search NIH Clinical Center for Hemiplegia

Cochrane evidence based reviews: hemiplegia

Genetic Tests for Hemiplegia

Genetic tests related to Hemiplegia:

id Genetic test Affiliating Genes
1 Hemiplegia 29

Anatomical Context for Hemiplegia

MalaCards organs/tissues related to Hemiplegia:

39
Brain, Testes, Bone, Eye, Cortex, Skin, Spinal Cord

Publications for Hemiplegia

Articles related to Hemiplegia:

(show top 50) (show all 801)
id Title Authors Year
1
Rehabilitation for hemiplegia using an upper limb training system based on a force direction. ( 28813875 )
2017
2
Challenges describing motor profiles in alternating hemiplegia of childhood. ( 28556907 )
2017
3
Alternating Hemiplegia of Childhood: Pharmacological treatment of 30 Italian patients. ( 28249736 )
2017
4
Dengue fever triggering hemiconvulsion hemiplegia epilepsy in a child. ( 28488637 )
2017
5
More Than a Decade of Misdiagnosis of Alternating Hemiplegia of Childhood with Catastrophic Outcome. ( 28900444 )
2017
6
Topiramate Therapy in Alternating Hemiplegia of Childhood. ( 28502069 )
2017
7
Diagnostic Challenge of Diffusion Tensor Imaging in a Patient With Hemiplegia After Traumatic Brain Injury. ( 28289648 )
2017
8
Hemiconvulsion-hemiplegia-epilepsy syndrome in a child with pre-existing cerebral pathology. ( 28652222 )
2017
9
Kinect-based gait analyses of patients with Parkinson's disease, patients with stroke with hemiplegia, and healthy adults. ( 28266138 )
2017
10
Motor function domains in alternating hemiplegia of childhood. ( 28543714 )
2017
11
REACH: study protocol of a randomised trial of rehabilitation very early in congenital hemiplegia. ( 28928195 )
2017
12
An Infant With Epilepsy and Recurrent Hemiplegia due to Compound Heterozygous Variants in ATP1A2. ( 28811059 )
2017
13
Alternating Hemiplegia and Epilepsia Partialis Continua: A new phenotype for a novel compound TBC1D24 mutation. ( 28292732 )
2017
14
Intermittent Hemiplegia in a Boy with Primary Moyamoya Disease: A Case Report from Iran. ( 28698731 )
2017
15
Combined therapy using botulinum toxin A and single-joint hybrid assistive limb for upper-limb disability due to spastic hemiplegia. ( 28131185 )
2017
16
Modulating anosognosia for hemiplegia: The role of dangerous actions in emergent awareness. ( 28501758 )
2017
17
ATP1A3 mutant patient with alternating hemiplegia of childhood and brain spectroscopic abnormalities. ( 28716275 )
2017
18
Ocular Motor Function in Children with Spastic Hemiplegia Evaluated by the Ocular Motor Score. ( 28771056 )
2017
19
Effects of weight training time on bone mineral density of patients with secondary osteoporosis after hemiplegia. ( 28450926 )
2017
20
Diagnosis and Treatment of Alternating Hemiplegia of Childhood. ( 28337648 )
2017
21
Alternating hemiplegia of childhood and a pathogenic variant of ATP1A3: a case report and pathophysiological considerations. ( 28637637 )
2017
22
Alternating Hemiplegia of Childhood with Novel Features. ( 28138908 )
2017
23
A Randomized Controlled Study: Effectiveness of Functional Electrical Stimulation on Wrist and Finger Flexor Spasticity in Hemiplegia. ( 28462794 )
2017
24
Acute mental change and hemiplegia after autologous fat injection. ( 27352047 )
2016
25
Recognizable facial features in patients with alternating hemiplegia of childhood. ( 27312461 )
2016
26
Spontaneously Fluctuating Motor Cortex Excitability in Alternating Hemiplegia of Childhood: A Transcranial Magnetic Stimulation Study. ( 26999520 )
2016
27
Reliability and validity of the Korean version of the community balance and mobility scale in patients with hemiplegia after stroke. ( 27630420 )
2016
28
The effect of Monkey Chair and Band exercise system on shoulder range of motion and pain in post-stroke patients with hemiplegia. ( 27630403 )
2016
29
Muscle Strength and Poststroke Hemiplegia: A Systematic Review of Muscle Strength Assessment and Muscle Strength Impairment. ( 27372002 )
2016
30
Hemiplegia following multiple bee sting. ( 27727866 )
2016
31
Feasibility of Using an Arm Weight-Supported Training System to Improve Hand Function Skills in Children With Hemiplegia. ( 27767944 )
2016
32
Evaluation of the Efficacy and Robustness of a Second Generation Implantable Stimulator in a Patient With Hemiplegia During 20 Years of Functional Electrical Stimulation of the Common Peroneal Nerve. ( 27121484 )
2016
33
Functional independence measure scores of patients with hemiplegia followed up at home and in university hospitals. ( 27065223 )
2016
34
A 55-Year-Old French Man With Sudden Hemiparesis and Hemiplegia. ( 26932936 )
2016
35
A 55-Year-Old French Man With Sudden Hemiparesis and Hemiplegia. ( 26932935 )
2016
36
Hemiplegia Following Mild Head Injury in a Child with Sturge-Weber Syndrome - A Diagnostic Dilemma. ( 27539768 )
2016
37
The Influence of Rocker Bar Ankle Foot Orthosis on Gait in Patients with Chronic Hemiplegia. ( 27265095 )
2016
38
Merging and Fractionation of Muscle Synergy Indicate the Recovery Process in Patients with Hemiplegia: The First Study of Patients after Subacute Stroke. ( 28090358 )
2016
39
Effects of Home-based Telesupervising Rehabilitation on Physical Function for Stroke Survivors with Hemiplegia: A Randomized Controlled Trial. ( 27386808 )
2016
40
Motor versus body awareness: Voxel-based lesion analysis in anosognosia for hemiplegia and somatoparaphrenia following right hemisphere stroke. ( 27494375 )
2016
41
Effects of Kinesio taping and Mcconnell taping on balance and walking speed of hemiplegia patients. ( 27190448 )
2016
42
Grip strength in post-stroke hemiplegia. ( 27065562 )
2016
43
Relation between muscle fiber conduction velocity and exerted dynamic characteristics of muscular tension in patients with hemiplegia caused by stroke. ( 27821946 )
2016
44
Effects of shoulder reaching exercise on the balance of patients with hemiplegia after stroke. ( 27512286 )
2016
45
De novo p.Arg756Cys mutation of ATP1A3 causes an atypical form of alternating hemiplegia of childhood with prolonged paralysis and choreoathetosis. ( 27634470 )
2016
46
Efficacy of two injection-site localisation techniques for botulinum toxin injections: a single-blind, crossover, randomised trial protocol among adults with hemiplegia due to stroke. ( 27852706 )
2016
47
Hyperintense lesion along the pyramidal tract on DWI in hypoglycaemic hemiplegia. ( 27060077 )
2016
48
Efficacy of Upper Extremity Robotic Therapy in Subacute Poststroke Hemiplegia: An Exploratory Randomized Trial. ( 27006452 )
2016
49
Influence of increased amount of exercise on improvements in walking ability of convalescent patients with post-stroke hemiplegia. ( 27065551 )
2016
50
Individual joint contribution to body weight support in the affected lower limb during walking in post-stroke hemiplegia. ( 27690285 )
2016

Variations for Hemiplegia

ClinVar genetic disease variations for Hemiplegia:

6
id Gene Variation Type Significance SNP ID Assembly Location
1 ATP1A3 NM_152296.4(ATP1A3): c.2839G> A (p.Gly947Arg) single nucleotide variant Pathogenic rs398122887 GRCh37 Chromosome 19, 42471896: 42471896

Expression for Hemiplegia

Search GEO for disease gene expression data for Hemiplegia.

Pathways for Hemiplegia

GO Terms for Hemiplegia

Cellular components related to Hemiplegia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 axon GO:0030424 9.62 ATP1A3 CALCA SCN1A TAC1
2 sarcolemma GO:0042383 9.37 ATP1A2 ATP1A3
3 sodium:potassium-exchanging ATPase complex GO:0005890 9.26 ATP1A2 ATP1A3
4 collagen type IV trimer GO:0005587 9.16 COL4A1 COL4A2
5 neuronal cell body GO:0043025 9.1 ATP1A3 CACNA1A CALCA SCN1A SLC1A3 TAC1
6 intercalated disc GO:0014704 8.96 ATP1A2 SCN1A

Biological processes related to Hemiplegia according to GeneCards Suite gene sharing:

(show all 20)
id Name GO ID Score Top Affiliating Genes
1 ion transport GO:0006811 9.95 ATP1A2 ATP1A3 CACNA1A SCN1A SLC1A3
2 sodium ion transport GO:0006814 9.74 ATP1A2 ATP1A3 SCN1A
3 adult walking behavior GO:0007628 9.59 CACNA1A SCN1A
4 membrane depolarization during action potential GO:0086010 9.58 CACNA1A SCN1A
5 potassium ion import GO:0010107 9.58 ATP1A2 ATP1A3
6 positive regulation of ossification GO:0045778 9.56 CALCA TAC1
7 cell communication by electrical coupling involved in cardiac conduction GO:0086064 9.54 ATP1A2 ATP1A3
8 cellular sodium ion homeostasis GO:0006883 9.52 ATP1A2 ATP1A3
9 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.51 ATP1A2 ATP1A3
10 cellular response to steroid hormone stimulus GO:0071383 9.49 ATP1A2 ATP1A3
11 collagen-activated tyrosine kinase receptor signaling pathway GO:0038063 9.48 COL4A1 COL4A2
12 cellular potassium ion homeostasis GO:0030007 9.46 ATP1A2 ATP1A3
13 positive regulation of cytosolic calcium ion concentration GO:0007204 9.46 ADCY5 CACNA1A CALCA TAC1
14 ATP hydrolysis coupled transmembrane transport GO:0090662 9.43 ATP1A2 ATP1A3
15 neuromuscular process controlling balance GO:0050885 9.43 ADCY5 CACNA1A SLC1A3
16 sodium ion export from cell GO:0036376 9.4 ATP1A2 ATP1A3
17 response to glycoside GO:1903416 9.37 ATP1A2 ATP1A3
18 neurotransmitter uptake GO:0001504 9.32 ATP1A2 SLC1A3
19 response to pain GO:0048265 9.13 CACNA1A CALCA TAC1
20 regulation of blood pressure GO:0008217 8.92 ACTA2 ATP1A2 CALCA TAC1

Molecular functions related to Hemiplegia according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 8.96 ATP1A2 ATP1A3
2 steroid hormone binding GO:1990239 8.62 ATP1A2 ATP1A3

Sources for Hemiplegia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....