HFE1
MCID: HMC003
MIFTS: 72

Hemochromatosis (HFE1) malady

Categories: Genetic diseases, Rare diseases, Liver diseases, Metabolic diseases

Aliases & Classifications for Hemochromatosis

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Aliases & Descriptions for Hemochromatosis:

Name: Hemochromatosis 52 11 71 48 25 12 50 38 39 13 68
Hereditary Hemochromatosis 25 70 27 50 68
Hemochromatosis Type 1 11 48 70
Haemochromatosis 11 71 25
Symptomatic Form of Hfe-Related Hereditary Hemochromatosis 11 54
Symptomatic Form of Classic Hemochromatosis 11 54
Symptomatic Form of Hemochromatosis Type 1 11 54
Hemochromatosis, Type 1 52 68
Iron Storage Disorder 11 25
Hemochromatosis 1 70 27
Hfe1 11 70
Hlah 25 70
Hh 25 70
Von Recklenhausen-Applebaum Disease 25
Primary Hereditary Hemochromatosis 70
 
Troisier-Hanot-Chauffard Syndrome 25
Hfe Hemochromatosis, Modifier of 52
Hereditary Haemochromatosis 25
Familial Hemochromatosis 25
Genetic Hemochromatosis 25
Classic Hemochromatosis 48
Hemochromatosis Classic 48
Primary Hemochromatosis 25
Pigmentary Cirrhosis 25
Bronzed Cirrhosis 25
Bronze Cirrhosis 68
Bronze Diabetes 25
Diabetes Bronze 11
Hc 25

Characteristics:

HPO:

64
hemochromatosis:
Inheritance: autosomal recessive inheritance

Classifications:



External Ids:

OMIM52 235200
Disease Ontology11 DOID:0111029, DOID:2352
MeSH39 D006432
NCIt45 C84481
Orphanet54 ORPHA465508
ICD10 via Orphanet31 E83.1
MedGen37 C0392514

Summaries for Hemochromatosis

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OMIM:52 Hereditary hemochromatosis is an autosomal recessive disorder of iron metabolism wherein the body accumulates excess... (235200) more...

MalaCards based summary: Hemochromatosis, also known as hereditary hemochromatosis, is related to hemochromatosis, type 4 and hemochromatosis, type 3, and has symptoms including abdominal pain, constipation and diarrhea. An important gene associated with Hemochromatosis is HFE (Hemochromatosis), and among its related pathways are Hfe effect on hepcidin production and Signaling by BMP. The drug deferoxamine mesylate has been mentioned in the context of this disorder. Affiliated tissues include liver, heart and pancreas, and related mouse phenotypes are cardiovascular system and hematopoietic system.

NIH Rare Diseases:48 Hemochromatosis is a condition in which too much iron builds up in the body (iron overload). accumulation of iron in the organs is toxic and can result in organ failure. while many organs can be affected, it may especially affect the liver, heart, and pancreas. symptoms of hemochromatosis tend to develop gradually and often don't appear until middle age or later. the condition may not be diagnosed until iron accumulation is excessive. early symptoms may be vague, such as fatigue or weakness. other symptoms or features may include joint pain, abdominal pain, loss of sex drive, arthritis, liver disease, diabetes, heart problems, and skin discoloration. hemochromatosis may be hereditary or acquired (secondary) due to another condition such as anemia, chronic liver disease, or an infection. there is also a neonatal form. hereditary hemochromatosis is classified by type based on age of onset, genetic cause and mode of inheritance:hemochromotosis type 1 hemochromatosis type 2 hemochromatosis type 3 hemochromatosis type 4 treatment usually involves removing blood (phlebotomy), which prevents additional organ damage but does not reverse existing damage. last updated: 1/11/2017

UniProtKB/Swiss-Prot:70 Hemochromatosis 1: A disorder of iron metabolism characterized by iron overload. Excess iron is deposited in a variety of organs leading to their failure, and resulting in serious illnesses including cirrhosis, hepatomas, diabetes, cardiomyopathy, arthritis, and hypogonadotropic hypogonadism. Severe effects of the disease usually do not appear until after decades of progressive iron loading.

MedlinePlus:38 Hemochromatosis is a disease in which too much iron builds up in your body. your body needs iron but too much of it is toxic. if you have hemochromatosis, you absorb more iron than you need. your body has no natural way to get rid of the extra iron. it stores it in body tissues, especially the liver, heart, and pancreas. the extra iron can damage your organs. without treatment, it can cause your organs to fail. there are two types of hemochromatosis. primary hemochromatosis is an inherited disease. secondary hemochromatosis is usually the result of something else, such as anemia, thalassemia, liver disease, or blood transfusions. many symptoms of hemochromatosis are similar to those of other diseases. not everyone has symptoms. if you do, you may have joint pain, fatigue, general weakness, weight loss, and stomach pain. your doctor will diagnose hemochromatosis based on your medical and family histories, a physical exam, and the results from tests and procedures. treatments include removing blood (and iron) from your body, medicines, and changes in your diet. nih: national heart, lung, and blood institute

Genetics Home Reference:25 Hereditary hemochromatosis is a disorder that causes the body to absorb too much iron from the diet. The excess iron is stored in the body's tissues and organs, particularly the skin, heart, liver, pancreas, and joints. Because humans cannot increase the excretion of iron, excess iron can overload and eventually damage tissues and organs. For this reason, hereditary hemochromatosis is also called an iron overload disorder.

Disease Ontology:11 A metal metabolism disorder characterized by the accumulation of iron in various organs of the body.

Related Diseases for Hemochromatosis

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Diseases in the Hemochromatosis family:

Hemochromatosis, Type 2a Hemochromatosis, Type 4
Hemochromatosis, Type 3 Hemochromatosis, Type 5
Hemochromatosis, Type 2b Hemochromatosis Type 2
Juvenile Hereditary Hemochromatosis Tfr2-Related Hereditary Hemochromatosis
Slc40a1-Related Hereditary Hemochromatosis Hamp-Related Juvenile Hemochromatosis

Diseases related to Hemochromatosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 245)
idRelated DiseaseScoreTop Affiliating Genes
1hemochromatosis, type 412.4
2hemochromatosis, type 312.4
3hemochromatosis type 212.2
4hemochromatosis, type 2a12.2
5hemochromatosis, neonatal12.2
6hemochromatosis, type 2b12.1
7hemochromatosis, type 512.1
8juvenile hereditary hemochromatosis12.0
9tfr2-related hereditary hemochromatosis12.0
10hfe-associated hereditary hemochromatosis11.9
11slc40a1-related hereditary hemochromatosis11.8
12hamp-related juvenile hemochromatosis11.7
13hjv -related juvenile hemochromatosis11.7
14hypotrichosis 111.5
15hajdu-cheney syndrome11.5
16iron overload in africa11.5
17tumoral calcinosis, hyperphosphatemic, familial11.4
18dyskeratosis congenita, x-linked11.4
19heart-hand syndrome, slovenian type11.3
20hypogonadotropic hypogonadism 7 without anosmia11.3
21hemicrania continua11.2
22porphyria cutanea tarda11.1
23liver disease11.1
24hepatocellular carcinoma11.1
25hypotonia-cystinuria syndrome11.0
26alzheimer disease11.0
27hypogonadotropic hypogonadism 2 with or without anosmia10.9
28hypothalamic hamartomas10.9
29dyserythropoietic anemia, congenital, type ia10.9
30iron metabolism disease10.9
31dyskeratosis congenita, autosomal dominant 110.8
32dyskeratosis congenita, autosomal recessive 510.8
33kallmann syndrome10.8
34hyperinsulinism-hyperammonemia syndrome10.7
35hypotrichosis simplex10.7
36chondrocalcinosis 210.7
37dyserythropoietic anemia, congenital, type ib10.7
38hypogonadotropic hypogonadism 13 with or without anosmia10.6
39hypogonadotropic hypogonadism 15 with or without anosmia10.6
40hypogonadotropic hypogonadism 4 with or without anosmia10.6
41hypogonadotropic hypogonadism 18 with or without anosmia10.6
42hypogonadotropic hypogonadism 11 with or without anosmia10.6
43hypogonadotropic hypogonadism 17 with or without anosmia10.6
44hypogonadotropic hypogonadism 16 with or without anosmia10.6
45hypogonadotropic hypogonadism with or without anosmia10.6
46hypogonadotropic hypogonadism 20 with or without anosmia10.6
47hypogonadotropic hypogonadism 12 with or without anosmia10.6
48hypogonadotropic hypogonadism 5 with or without anosmia10.6
49hypogonadotropic hypogonadism 9 with or without anosmia10.6
50hypogonadotropic hypogonadism 6 with or without anosmia10.6

Graphical network of the top 20 diseases related to Hemochromatosis:



Diseases related to hemochromatosis

Symptoms & Phenotypes for Hemochromatosis

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Symptoms by clinical synopsis from OMIM:

235200

Clinical features from OMIM:

235200

Human phenotypes related to Hemochromatosis:

 54 64 (show all 39)
id Description HPO Frequency Orphanet Frequency HPO Source Accession
1 hypogonadism64 54 Very frequent (99-80%) HP:0000135
2 hyperpigmentation of the skin64 54 Very frequent (99-80%) HP:0000953
3 increased serum ferritin64 54 Very frequent (99-80%) HP:0003281
4 fatigue64 54 Very frequent (99-80%) HP:0012378
5 gynecomastia64 54 Frequent (79-30%) HP:0000771
6 impotence64 54 Frequent (79-30%) HP:0000802
7 abnormality of the hypothalamus-pituitary axis64 54 Frequent (79-30%) HP:0000864
8 chondrocalcinosis64 54 Frequent (79-30%) HP:0000934
9 joint dislocation64 54 Frequent (79-30%) HP:0001373
10 limitation of joint mobility64 54 Frequent (79-30%) HP:0001376
11 hepatic steatosis64 54 Frequent (79-30%) HP:0001397
12 hepatomegaly64 54 Frequent (79-30%) HP:0002240
13 arthralgia64 54 Frequent (79-30%) HP:0002829
14 arthropathy64 54 Frequent (79-30%) HP:0003040
15 retinopathy64 54 Occasional (29-5%) HP:0000488
16 diabetes mellitus64 54 Occasional (29-5%) HP:0000819
17 osteoporosis64 54 Occasional (29-5%) HP:0000939
18 cirrhosis64 54 Occasional (29-5%) HP:0001394
19 cholestasis64 54 Occasional (29-5%) HP:0001396
20 hepatocellular carcinoma64 54 Occasional (29-5%) HP:0001402
21 ascites64 54 Occasional (29-5%) HP:0001541
22 alopecia64 54 Occasional (29-5%) HP:0001596
23 congestive heart failure64 54 Occasional (29-5%) HP:0001635
24 cardiomyopathy64 54 Occasional (29-5%) HP:0001638
25 exocrine pancreatic insufficiency64 54 Occasional (29-5%) HP:0001738
26 splenomegaly64 54 Occasional (29-5%) HP:0001744
27 vertigo64 54 Occasional (29-5%) HP:0002321
28 peripheral neuropathy64 54 Occasional (29-5%) HP:0009830
29 azoospermia64 HP:0000027
30 testicular atrophy64 HP:0000029
31 hypogonadotrophic hypogonadism64 HP:0000044
32 amenorrhea64 HP:0000141
33 telangiectasia64 HP:0001009
34 cardiomegaly64 HP:0001640
35 abnormal glucose tolerance64 HP:0001952
36 pleural effusion64 HP:0002202
37 elevated hepatic transaminases64 HP:0002910
38 increased serum iron64 HP:0003452
39 arrhythmia64 HP:0011675

UMLS symptoms related to Hemochromatosis:


abdominal pain, constipation, diarrhea, dyspepsia, heartburn, icterus, nausea and vomiting, gastrointestinal gas

MGI Mouse Phenotypes related to Hemochromatosis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053859.5B2M, BMP2, CP, CYBRD1, FXN, HEPH
2MP:00053979.2B2M, BMP2, CP, HEPH, HFE, HFE2
3MP:00053879.0B2M, BMP2, CP, FXN, HEPH, HFE
4MP:00053768.6ACO1, B2M, BMP2, CP, CYBRD1, FXN
5MP:00053708.5B2M, CP, CYBRD1, HEPH, HFE, HFE2

Drugs & Therapeutics for Hemochromatosis

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Drugs for Hemochromatosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 42)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
IronapprovedPhase 4, Phase 3, Phase 2, Phase 111657439-89-623925
Synonyms:
02583_FLUKA
12310_ALDRICH
12310_RIEDEL
129048-51-7
14067-02-8
161135-39-3
190454-13-8
195161-83-2
199281-22-6
209309_ALDRICH
209309_SIAL
255637_ALDRICH
266213_ALDRICH
266256_ALDRICH
267945_ALDRICH
267953_ALDRICH
26Fe
338141_ALDRICH
356808_ALDRICH
356824_ALDRICH
356832_ALDRICH
39344-71-3
3ZhP
413054_ALDRICH
443783-52-6
44890_ALDRICH
44890_FLUKA
675141-17-0
70884-35-4
73135-38-3
7439-89-6
8011-79-8
8053-60-9
AC1L2N38
ATW 230
ATW 432
Ancor B
Ancor en 80/150
Armco iron
Atomel 28
Atomel 300M200
Atomel 500M
Atomel 95
Atomiron 44MR
Atomiron 5M
Atomiron AFP 25
Atomiron AFP 5
C00023
C3518_SIAL
C3518_SIGMA
CCRIS 1580
CHEBI:18248
CID23925
Carbonyl iron
Copy Powder CS 105-175
D007501
DB01592
DSP 1000
DSP 128B
DSP 135
DSP 135C
DSP 138
Diseases (animal), iron overload
Diseases, iron overload
EF 1000
EF 250
EFV 200/300
EFV 250
EFV 250/400
EINECS 231-096-4
 
Ed-In-Sol
Eisen
Electrolytic iron
F 60 (metal)
FE
FT 3 (element)
Fe
Fe-40
Fe1+
Feronate
Ferretts
Ferro-Caps
Ferro-Time
Ferrousal
Ferrovac E
Ferrum
Ferrum metallicum
GS 6
HF 2 (element)
HL (iron)
HQ (metal)
HS (iron)
HS 4849
HSDB 604
Hemocyte
Hierro
Hoeganaes ATW 230
Hoeganaes EH
IRMM524A_FLUKA
IRMM524B_FLUKA
IRON
Iron (Fe)
Iron (Fe1+)
Iron ion (Fe+)
Iron ion(1+)
Iron monocation
Iron powder
Iron standard for AAS
Iron(1+)
Iron(1+) ion
Iron(III) nitrate solution
Iron, carbonyl
Iron, electrolytic
Iron, elemental
Iron, ion (Fe1+)
Iron, ion (Fe1+) (8CI,9CI)
Iron, reduced
LOHA
LS-3196
MolPort-003-925-001
NC 100
PZh-1M3
PZh-2
PZh1M1
PZh2M
PZh2M1
PZh2M2
PZh3
PZh3M
PZh4M
PZhO
Reduced iron
Remko
SUY-B 2
Siderol
UNII-E1UOL152H7
Vitedyn-Slo
Yieronia
fer
ferrous iron
hierro
2
Omeprazoleapproved, investigational, vet_approvedPhase 434873590-58-64594
Synonyms:
( -)-Omeprazole
(-)-Omeprazole
(S)-(-)-Omeprazole
(S)-Omeprazole
119141-89-8
131959-78-9
172964-80-6
2,3,5-Trimethylpyridine/Omeprazole
2-(((3,5-Dimethyl-4-methoxy-2-pyridyl)methyl)sulfinyl)-5-methoxy-1H-benzimidazole
2-({[3,5-dimethyl-4-(methyloxy)pyridin-2-yl]methyl}sulfinyl)-5-(methyloxy)-1H-benzimidazole
5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridyl)methyl)sulfinyl)benzimidazole
5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
5-Methoxy-2[(4-methoxy-3,5-dimethyl-2-pyridyl)methylsulfinyl]-1H-benzimidazole
5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole
6-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole
73590-58-6
AC-401
AC1L1IIJ
AGI-010
AKOS005066653
AULCER
Antra
Antra MUPS
Audazol
Aulcer
Axagon
BIDD:GT0189
BPBio1_000425
BRD-A55962179-001-04-9
BSPBio_000385
Belmazol
Bio-0888
C07324
CAS-73590-58-6
CCRIS 7099
CHEBI:519601
CHEBI:7772
CHEMBL1503
CID4594
CPD000058847
Ceprandal
D00455
DB00338
DB00736
DM-3458
Danlox
Demeprazol
Desec
Dizprazol
Dudencer
Elgam
Emeproton
Emilok
Epirazole
Erbolin
Esomeprazole
Esomperazole
Esopral
Exter
Gasec
Gastrimut
Gastroloc
Gibancer
H 168-68
H 168/68
H-168/68
H168/68
HMS1528I05
HMS1569D07
HMS2052G17
HMS2090E16
HMS2090F11
HSDB 3575
I06-0705
IDI1_032523
Indurgan
Inhibitron
Inhipump
LS-7629
Lensor
Logastric
Lomac
Losec
Losec, Omesec, Prilosec, Zegerid, Omeprazole
Lucen
MLS000069373
MLS001076112
MLS001424148
Maybridge4_002645
Mepral
Miol
Miracid
MolPort-003-666-741
MolPort-003-807-515
MolPort-003-849-702
Mopral
Morecon
NCGC00016925-01
 
NCGC00016925-02
NCGC00021522-03
NCGC00021522-04
NCGC00021522-05
Nexiam
Nexium
Nexium IV
Nilsec
Nopramin
Nuclosina
O0359
O104_SIGMA
OMEP
OMP
OMZ
Ocid
Olexin
Olit
Omapren
Omebeta
Omebeta 20
Omed
Omegast
Omepradex
Omepral
Omeprazol
Omeprazol [INN-Spanish]
Omeprazole
Omeprazole (JAN/USP/INN)
Omeprazole Pellets
Omeprazole [USAN:INN:BAN:JAN]
Omeprazole delayed-release
Omeprazole magnesium
Omeprazolum
Omeprazolum [INN-Latin]
Omeprazon
Omeprazone
Omeprol
Omesek
Omez
Omezol
Omezolan
Omid
Omisec
Omizac
Ompanyt
Ortanol
Osiren
Ozoken
Paprazol
Parizac
Pepticum
Pepticus
Peptilcer
Prazentol
Prazidec
Prazolit
Prestwick0_000493
Prestwick1_000493
Prestwick2_000493
Prestwick3_000493
Prestwick_808
Prilosec
Prilosec (TN)
Prilosec OTC
Procelac
Proclor
Prysma
Ramezol
Regulacid
Result
S1389_Selleck
SAM001246900
SAN-15
SMR000058847
SPBio_002306
STK623746
Sanamidol
Secrepina
TL8005099
Tedec Ulceral
UNII-KG60484QX9
UPCMLD-DP075
UPCMLD-DP075:001
Ulceral
Ulcesep
Ulcometion
Ulcozol
Ulcsep
Ulsen
Ultop
Ulzol
Victrix
Zefxon
Zegerid
Zepral
Zimor
Zoltum
esomeprazol
omeprazole
3
Deferasiroxapproved, investigationalPhase 4, Phase 1, Phase 289201530-41-85493381
Synonyms:
Deferasiroxum
Deferasiroxum [inn-latin]
 
Exjade
ICL 670
ICL 670a
deferasirox
4
DeferiproneapprovedPhase 4, Phase 3, Phase 2, Phase 15730652-11-02972
Synonyms:
1,2-Dimethyl-3-hydroxypyrid-4-one
3-Hydroxy-1,2-dimethyl-4(1H)-pyridone
APO-066
CP-20
DN-180-01-AF
Deferipron
 
Deferiprona
Deferiproni
Deferipronum
Deferypron
Dimethylhydroxypyridone
Défériprone
Ferriprox
PL-1
5
Deferoxamineapproved, investigationalPhase 4, Phase 3, Phase 24770-51-92973
Synonyms:
DF B
DFO
DFOA
DFOM
Deferoxamide B
Deferoxamin
Deferoxamina
 
Deferoxamine B
Deferoxaminum
Deferrioxamine
Deferrioxamine B
Deferrioxamine b
Desferrioxamine
Desferrioxamine B
Déferoxamine
N-Benzoylferrioxamine B
6AntacidsPhase 41842
7
Proton pump inhibitorsPhase 41123
Synonyms:
 
PPIs
8Anti-Ulcer AgentsPhase 41842
9Gastrointestinal AgentsPhase 48402
10Liver ExtractsPhase 4, Phase 24067
11Chelating AgentsPhase 4, Phase 3, Phase 2, Phase 11423
12Iron Chelating AgentsPhase 4, Phase 3, Phase 2, Phase 1226
13
EthanolapprovedPhase 3213764-17-5702
Synonyms:
(C6-C9)Alkyl alcohol
02483_FLUKA
02851_FLUKA
02853_FLUKA
02854_FLUKA
02855_FLUKA
02856_FLUKA
02856_SIAL
02857_FLUKA
02857_SIAL
02858_FLUKA
02858_SIAL
02860_FLUKA
02865_FLUKA
02865_SIAL
02870_FLUKA
02870_SIAL
02875_FLUKA
02877_FLUKA
02878_FLUKA
02882_FLUKA
02882_SIAL
02883_FLUKA
02884_FLUKA
02890_FLUKA
02890_SIAL
02891_FLUKA
02891_SIAL
1-Hydroxyethane
100C.NPA
121182-78-3
187380_ALDRICH
187380_SIAL
24102_RIEDEL
24102_SIAL
24103_RIEDEL
24103_SIAL
24105_RIEDEL
24105_SIAL
24106_RIEDEL
24106_SIAL
24194_RIEDEL
24194_SIAL
245119_ALDRICH
245119_SIAL
270741_ALDRICH
270741_SIAL
277649_ALDRICH
277649_SIAL
2858_SIGMA
29221_FLUKA
32205_RIEDEL
32205_SIAL
32221_RIEDEL
32221_SIAL
32294_RIEDEL
32294_SIAL
34870_SIAL
34963_RIEDEL
39278_FLUKA
40210_ALDRICH
40210_RIEDEL
41322_FLUKA
458600_ALDRICH
458600_SIAL
459828_ALDRICH
459828_SIAL
459836_ALDRICH
459836_SIAL
459844_SIAL
48075_SUPELCO
493511_SIAL
493538_ALDRICH
493538_SIAL
493546_ALDRICH
493546_SIAL
64-17-5
676829_SIAL
68475-56-9
71076-86-3
71329-38-9
8000-16-6
8024-45-1
AC1L19TW
AC1Q31MM
AHD 2000
AI3-01706
ALCOHOL 5% IN D5-W
Absolute Alcohol
Absolute Ethanol
Absolute alcohol
Absolute ethanol
Absolute ethyl alcohol
Aethanol
Aethanol [German]
Aethylalkohol
Alcare Hand Degermer
Alcohol
Alcohol (USP)
Alcohol (ethyl)
Alcohol Anhydrous
Alcohol [USP]
Alcohol anhydrous
Alcohol dehydrated
Alcohol denatured
Alcohol etílico
Alcohol, Absolute
Alcohol, Dehydrated
Alcohol, Diluted
Alcohol, Grain
Alcohol, anhydrous
Alcohol, dehydrated
Alcohol, denatured
Alcohol, diluted
Alcohol, ethyl
Alcohols
Alcohols, C1-3
Alcohols, C30
Alcohols, C6-9
Alcool Ethylique
Alcool Etilico
Alcool ethylique
Alcool etilico
Alcool éthylique
Algrain
Alkohol
Alkohol [German]
Alkoholu Etylowego
Alkoholu etylowego
Aminoethanol
Anhydrol
Anhydrol PM 4085
Anhydrous alcohol
Anhydrous ethanol
Beta-Aminoethanol
Beta-Aminoethyl Alcohol
Beta-Ethanolamine
Beta-Hydroxyethylamine
C00469
C2H5OH
C2H6O
CCRIS 945
CDA 19
CDA 19-200
CHEBI:16236
CHEMBL545
CID702
Caswell No. 426
Caswell No. 430
Colamine
Cologne Spirit
Cologne spirit
Cologne spirits
 
D000431
D00068
DB00898
Dehydrated Ethanol
Dehydrated alcohol
Dehydrated ethanol
Denatured Alcohol
Denatured Alcohol Cd-10
Denatured Alcohol Cd-5
Denatured Alcohol Cd-5a
Denatured Alcohol Sd-1
Denatured Alcohol Sd-13a
Denatured Alcohol Sd-17
Denatured Alcohol Sd-23a
Denatured Alcohol Sd-28
Denatured Alcohol Sd-30
Denatured Alcohol Sd-39b
Denatured Alcohol Sd-39c
Denatured Alcohol Sd-3a
Denatured Alcohol Sd-40m
Denatured Ethanol
Denatured alcohol
Denatured ethanol
Desinfektol EL
Diluted Alcohol
Distilled spirits
E2385_SIGMA
E7023_ALDRICH
E7023_SIAL
E7148_ALDRICH
E7148_SIAL
E7517_SIGMA
EINECS 200-578-6
EINECS 270-649-4
EOH
EOX
ETA
Envision Conditioner Pdd 9020
Esumiru WK 88
EtOH
Etanolo
Etanolo [Italian]
Ethanol (9CI)
Ethanol 200 Proof
Ethanol 200 proof
Ethanol Absolute
Ethanol Absolute Bp
Ethanol Anhydrous
Ethanol Extra Pure
Ethanol Vapor
Ethanol [JAN]
Ethanol solution
Ethanol, Silent Spirit
Ethanol, undenatured
Ethanolum anhydricum
Ethicap
Ethyl Alcohol
Ethyl Alcohol & Water, 10%
Ethyl Alcohol & Water, 20%
Ethyl Alcohol & Water, 30%
Ethyl Alcohol & Water, 40%
Ethyl Alcohol & Water, 5%
Ethyl Alcohol & Water, 50%
Ethyl Alcohol & Water, 60%
Ethyl Alcohol & Water, 70%
Ethyl Alcohol & Water, 80%
Ethyl Alcohol & Water, 95%
Ethyl Alcohol & Water, 96%
Ethyl Alcohol Anhydrous
Ethyl Alcohol, Anhydrous
Ethyl Alcohol, Denatured
Ethyl Hydrate
Ethyl Hydroxide
Ethyl alc
Ethyl alcohol
Ethyl alcohol anhydrous
Ethyl alcohol in alcoholic beverages
Ethyl alcohol usp
Ethyl hydrate
Ethyl hydroxide
Ethylalcohol
Ethylalcohol [Dutch]
Ethylol
Ethylolamine
Ethyloxy Group
Etylowy alkohol
FEMA No. 2419
FEMA Number 2419
Fermentation alcohol
Glycinol
Grain alcohol
HSDB 531
HSDB 82
HYDROXYETHYL GROUP
Hinetoless
Hydroxyethane
I14-12648
IMS 99
Infinity Pure
Jaysol
Jaysol S
LS-1539
LTBB002977
Lux
Methylated Spirit Mineralised
Methylated spirit
Methylcarbinol
MolPort-001-785-844
Molasses alcohol
NCGC00091458-01
NCI-C03134
NSC 85228
NSC85228
Oxydimethylene Group
Potato alcohol
Punctilious ethyl alcohol
Pyro
QMHAIh@
Reagent Alcohol
Ru-Tuss Expectorant
SDA 3A
SDA 40-2
SDM No. 37
SY Fresh M
Sekundasprit
Silent spirit
Spirit
Spirits of wine
Spiritus vini
Spirt
Synasol
Tecsol
Tecsol C
Thanol
Thiofaco M-50
UNII-3K9958V90M
USAF EK-1597
Undenatured Ethanol
WLN: Q2
absolute alcohol
alcohol
alcohol etilico
bmse000297
etanol
ethanol
ethyl alcohol
grain alcohol
nchem.651-comp3c
nchembio.552-comp10
nchembio.94-comp20
spiritus vini
Äthanol
Äthylalkohol
éthanol
14
HydroxyureaapprovedPhase 3223127-07-13657
Synonyms:
1-HYDROXYUREA
127-07-1
4-03-00-00170 (Beilstein Handbook Reference)
55291_FLUKA
AC1L1GF8
AC1Q4ZXK
AI3-51139
BB_SC-7256
BRN 1741548
BSPBio_002164
Bio1_000451
Bio1_000940
Bio1_001429
Biosupressin
C07044
CCRIS 958
CHEBI:44423
CHEMBL467
CID3657
Carbamohydroxamic Acid
Carbamohydroxamic acid
Carbamohydroximic Acid
Carbamohydroximic acid
Carbamohydroxyamic Acid
Carbamohydroxyamic acid
Carbamoyl Oxime
Carbamoyl oxime
Carbamyl Hydroxamate
Carbamyl hydroxamate
Carrbamoyl Oxime
D00341
D006918
DB01005
DRG-0253
DivK1c_000556
Droxia
Droxia (TM)
Droxia (TN)
E0723DBA-5AF3-49D1-B5F6-59420AB87AC9
EINECS 204-821-7
EU-0100596
FT-0083575
H 8627
H0310
H20210
H8627_SIGMA
HMS1920F09
HMS2091L17
HMS501L18
HSDB 6887
HU
HYDREA (TN)
HYDROXY-UREA
Hidrix
Hidroxicarbamida
Hidroxicarbamida [INN-Spanish]
Hydrea
Hydrea (TM)
Hydrea, Biosupressin, Cytodrox, Hydroxyurea
Hydreia
Hydroxicarbamidum
Hydroxycarbamid
Hydroxycarbamide
Hydroxycarbamide (JAN/INN)
Hydroxycarbamidum
Hydroxycarbamidum [INN-Latin]
Hydroxycarbamine
Hydroxyharnstoff
Hydroxyharnstoff [German]
Hydroxylurea
Hydroxyurea
Hydroxyurea (D4)
Hydroxyurea (USP)
Hydroxyurea [USAN:BAN]
Hydroxyurea(d4)
 
Hydura
Hydurea
I05-0250
IDI1_000556
Idrossicarbamide
Idrossicarbamide [DCIT]
Idrossicarbamide [Dcit]
KBio1_000556
KBio2_001389
KBio2_003957
KBio2_006525
KBio3_001384
KBioGR_000383
KBioSS_001389
LS-709
Litaler
Litalir
Lopac-H-8627
Lopac0_000596
MLS001332381
MLS001332382
MLS002153389
MolMap_000029
MolPort-000-003-971
Mylocel
N-(Aminocarbonyl) Hydroxyamine
N-Carbamoylhydroxylamine
N-HYDROXY UREA
N-Hydroxymocovina
N-Hydroxymocovina [Czech]
N-Hydroxyurea
NCGC00015520-01
NCGC00015520-02
NCGC00015520-07
NCGC00093974-01
NCGC00093974-02
NCGC00093974-03
NCGC00093974-04
NCGC00093974-05
NCI C04831
NCI-C04831
NCI60_002773
NCIMech_000139
NHY
NINDS_000556
NSC 32065
NSC32065
Onco-Carbide
Onco-carbide
Oncocarbide
Oxyurea
S-phase/G-1 interface inhibitor
S1896_Selleck
SK 22591
SMR000059149
SPBio_000247
SPECTRUM1500344
SQ 1089
SQ-1089
Siklos
Spectrum2_000064
Spectrum3_000462
Spectrum4_000012
Spectrum5_000836
Spectrum_000909
Sterile Urea
TL8000673
UNII-X6Q56QN5QC
Ureaphil
WLN: ZVMQ
carbamide oxide
hydroxyaminomethanamide
hydroxyurea
nchembio.573-comp3
nchembio.90-comp4
nchembio749-comp3
tetratogen: inhibits ribonucleoside diphosphate reductase
15Pharmaceutical SolutionsPhase 2, Phase 38192
16Nucleic Acid Synthesis InhibitorsPhase 34962
17
Cholecalciferolapproved, nutraceuticalPhase 287567-97-06221, 10883523, 5280795
Synonyms:
()-Vitamin D3
(+)-Vitamin D3
(+)-vitamin D3
(1S,3Z)-3-[(2e)-2-[(1R,3AR,7as)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-ol
(3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(3beta,Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
(3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(5E,7E)-9,10-Secocholesta-5,7,10-trien-3-ol
(5Z,7E)-(3S)-9,10-seco-5,7,10(19)-cholestatrien-3-ol
(5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol
1406-16-2
25(OH)D
3-beta,Z,7E-9,10-Secocholestr-5,7,10(19)-trien-3-ol
47763_SUPELCO
57651-82-8
67-97-0
7-Dehydrocholesterol activated
7-Dehydrocholesterol, Activated
7-Dehydrocholesterol, irradiated
7-Dehydrocholestrol, activated
8024-19-9
8050-67-7
89193_FLUKA
9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3-ol
9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3beta-ol
9,10-Secocholesta-5(Z),7(E),10(19)-trien-3(.beta.)-ol
9,10-Secocholesta-5,7,10(19)-trien-3-beta-ol
9,10-Secocholesta-5,7,10(19)-trien-3-ol
9,10-Secocholesta-5,7,10-trien-3-ol
AB1002422
AC-11697
AC1L1ECK
AC1L1M23
AC1LU7IZ
AC1NQXLN
AC1NR2UO
AC1NR2UR
AC1NR2UU
AC1NS4AJ
AC1NSHJX
AC1O5EOF
AC1O7GAV
AC1O7GQ3
AC1O8FEU
AC1O8PWJ
AC1OF2GI
AC1OF2GL
AC1OIEW5
AC1OIEWB
ACon1_001997
Activated 7-dehydrocholesterol
Arachitol
BPBio1_000460
BSPBio_000418
BSPBio_002408
Bio-0845
C05443
C1357_SIAL
C27H44O
C9756_SIGMA
C9774_SIAL
CAS-67-97-0
CC
CCRIS 5813
CCRIS 6286
CHEBI:283119
CHEBI:28940
CHEMBL1042
CHEMBL432780
CID10000117
CID10045875
CID10340013
CID10883523
CID10894379
CID11014566
CID11025493
CID11058152
CID11463269
CID1548921
CID2735
CID5280795
CID5283710
CID5283711
CID5283712
CID5353527
CID5363362
CID6221
CID6432644
CID6604201
CID6604662
CID6708595
CID6713938
CID6992015
CID6992016
CID7067439
CID7067440
CID7251172
CID7251174
CID9821465
Calciol
Cholecalciferol
Cholecalciferol (D3)
Cholecalciferol (JP15/USP)
Cholecalciferol D3
Cholecalciferol [USAN:BAN:JAN]
Cholecalciferol, D3
Cholecalciferolum
Colecalciferol
 
Colecalciferol (INN)
Colecalciferolo
Colecalciferolo [DCIT]
Colecalciferolum
Colecalciferolum [INN-Latin]
Colecalcipherol
D00188
D3-Vicotrat
D3-Vigantol
DB00169
Delsterol
Delta-D
Delta-D (TN)
Deparal
Devaron
DivK1c_006276
Duphafral D3 1000
EINECS 200-673-2
EINECS 215-797-2
EPA Pesticide Chemical Code 202901
Ebivit
FeraCol
Granuvit D3
HMS1569E20
HMS2092M12
HSDB 820
I05-0041
Irradiated 7-dehydrocholesterol
KBio1_001220
KBio2_001643
KBio2_004211
KBio2_006779
KBio3_001628
KBioGR_001602
KBioSS_001643
LMST03020001
LMST03020219
LMST03020220
LMST03020221
LS-1570
LS-825
LT00244775
MEGxm0_000458
Micro-dee
MolPort-001-740-051
MolPort-001-785-972
MolPort-003-666-021
MolPort-004-946-964
NCGC00016301-01
NCGC00017328-01
NCGC00091072-01
NCGC00142511-01
NCGC00159331-02
NCGC00159331-04
NCGC00178668-01
NCGC00179565-01
NCGC00179565-02
NEO Dohyfral D3
NSC 375571
NSC-375571
NSC375571
Oleovitamin D3
Prestwick0_000429
Prestwick1_000429
Prestwick2_000429
Prestwick3_000429
Prestwick_63
Provitamine
Provitina
Quintox
Rampage
Ricketon
SMP1_000068
SPBio_001298
SPBio_002357
SR-05000001559
SR-05000001559-3
ST057172
SpecPlus_000180
Spectrum2_001369
Spectrum3_000764
Spectrum4_001201
Spectrum_001163
TNP00266
Trivitan
UNII-1C6V77QF41
UPCMLD-DP152
UPCMLD-DP152:001
VITAMIN D
VITAMIN D3 POWDER
VITAMIN_D3
Vi-De3
Vi-de-3-hydrosol
VidDe-3-hydrosol
Videkhol
Vigantol
Vigorsan
Vitamin D-3
Vitamin D3
Vitamin D3 emulsifiable
Vitinc Dan-Dee-3
ZINC04474460
ZINC04492874
ZINC04492875
ZINC04492876
ZINC04492878
bmse000507
cholecalciferol
colecalciferolum
vitamin d-3
18
Ergocalciferolapproved, nutraceuticalPhase 2128150-14-65280793
Synonyms:
'Ergosterol irradiated'
(+)-Vitamin D2
(3-beta,5Z,7E,22E)-9,10-Secoergosta-5,7,10,(19),22-tetraen-3-ol
(3S,5Z,7E,14xi,17alpha,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol
(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol
(3beta,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(3beta,5Z,7e,22e)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
(5E,7E,22E)-9,10-Secoergosta-5,7,10,22-tetraen-3-ol
(5Z,7E,22E)-(3S)-9,10-seco-5,7,10(19),22-ergostatetraen-3-ol
(5Z,7E,22E)-(3S)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(5Z,7e,22e)-(3S)-9,10-Seco-5,7,10(19),22-ergostatetraen-3-ol
(5Z,7e,22e)-(3S)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
22-Tetraen 3beta 9,10,Secoergosta-5,7,10(19)-ol
31316-19-5
4-Methylene-3-[2-[tetrahydro-7a-methyl-1-(1,4,5-trimethyl-2-hexenyl)-4(3aH)-indanylidene]ethylidene]-Cyclohexanol
47768_SUPELCO
50-14-6
7489-18-1
7E677DC1-E1C4-4FC5-8F4A-BCE1857F7E87
8017-28-5
9,10,Secoergosta-5,7,10(19),22-tetraen 3.beta.-ol
9,10-Seco(5Z,7E,22E)-5,7,10(19),22-ergostatetraen-3-ol
9,10-Secoergosta-5,7,10(19),22-tetraen-3-beta-ol
9,10-Secoergosta-5,7,10(19),22-tetraen-3b-ol
95220_FLUKA
95220_SIGMA
AC-1355
AC1L1FIE
AC1NQXLH
AC1NS4DE
AC1NS9GI
AC1NSSVD
AC1NWAM3
AC1O5EDK
AC1O6WAM
ACon1_002187
Activated ergosterol
BPBio1_000418
BSPBio_000380
BSPBio_001974
Buco-D
C05441
C28H44O
CALCIFEROL IN A GELATIN MATRIX
CALCIFEROL, U.S.P.
CHEBI:28934
CHEMBL1536
CID11003810
CID3249
CID5280793
CID5315257
CID5353610
CID5356615
CID5702050
CID6432478
CID6536972
Calciferol
Calciferol (TN)
Calciferol (vitamin D2)
Calciferolum
Calciferon 2
Condacaps
Condocaps
Condol
Crtron
Crystallina
D-Arthin
D-Tracetten
D00187
DB00153
Daral
Davitamon D
Davitin
De-rat concentrate
Decaps
Dee-Osterol
Dee-Ron
Dee-Ronal
Dee-Roual
Deltalin
Deratol
Detalup
Diactol
Divit urto
Doral
Drisdol
Drisdol (TN)
E5750_SIGMA
EINECS 200-014-9
Ercalciol
Ergocalciferol
Ergocalciferol (D2)
Ergocalciferol (JP15/USP)
Ergocalciferol [INN:BAN:JAN]
Ergocalciferol oil
Ergocalciferol: Vitamin D
 
Ergocalciferolo
Ergocalciferolo [DCIT]
Ergocalciferols
Ergocalciferolum
Ergocalciferolum [INN-Latin]
Ergorone
Ergosterol activated
Ergosterol irradiated
Ergosterol, irradiated
Ertron
Fortodyl
Geltabs
Geltabs Vitamin D
HMS1920K20
HMS2091B19
HMS502I07
HSDB 819
Haliver
Hi-Deratol
Hyperkil
I05-0022
IDI1_000805
Infron
Irradiated ergosta-5,7,22-trien-3-beta-ol
Irradiated ergosta-5,7,22-trien-3.beta.-ol
Irradiated ergosta-5,7,22-trien-3beta-ol
Irradiated ergosterol
LMST03010001
LMST03010014
LS-3228
MEGxm0_000466
MLS001332467
MLS001332468
Metadee
Mina D2
MolPort-001-740-057
MolPort-001-793-930
MolPort-002-526-645
MolPort-003-666-178
MolPort-006-822-629
Mulsiferol
Mykostin
NCGC00142497-01
NCGC00179579-01
NCGC00179579-02
NSC 62792
NSC62792
Novovitamin-D
Oleovitamin D
Oleovitamin D, Synthetic
Oleovitamin D2
Osteil
Ostelin
Prestwick3_000420
Prestwick_554
Radiostol
Radstein
Radsterin
Rodine C
Rodinec
SMR000857106
SPECTRUM1500276
ST057150
STOCK1N-53397
Shock-ferol
Shock-ferol sterogyl
Sorex C.R
Sorex C.R.
Spectrum5_000666
Sterogyl
Synthetic Vitamin D
UNII-VS041H42XC
Uvesterol D
Uvesterol-D
VITAMIN D2
VITAMIN D2 WATER DISPERSABLE U.S.P.
VITAMIN_D2
Vigantol
Vio D
Vio-D
Viostdrol
Viosterol
Viosterol in Oil
Vitamin D2
Vitamin- D2
Vitamin-?D2
Vitamina D2
Vitavel-D
WLN: L56 FYTJ A1 BY1&1U1Y1&Y1&1 FU2U- BL6YYTJ AU1 DQ
ZINC04474571
ZINC04629876
beta-Ol
bmse000510
component of Geltabs Vitamin D
delta-Arthin
delta-Tracetten
ergocalciferol
vitamin d-2
19HepcidinsPhase 256
20Calcium, DietaryPhase 2, Phase 15713
21Trace ElementsPhase 2, Phase 16001
22MicronutrientsPhase 2, Phase 16001
23Anti-Infective AgentsPhase 222062
24Antirheumatic AgentsPhase 210956
25Interleukin 1 Receptor Antagonist ProteinPhase 299
26VaccinesPhase 1, Phase 26611
27VitaminsPhase 25282
28Bone Density Conservation AgentsPhase 23376
29vitamin dPhase 21724
30ErgocalciferolsPhase 21281
31CalciferolNutraceuticalPhase 21383
32Vitamin D2NutraceuticalPhase 21281
33
NifedipineapprovedPhase 111821829-25-44485
Synonyms:
101539-70-2
101554-38-5
21829-25-4
4-(2'-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridin-3,5-dicarbonsaeuredimethylester
5-22-04-00268 (Beilstein Handbook Reference)
60299-11-8 (mono-hydrochloride)
AC-11618
AC1L1I9V
AC1Q4254
AKOS002942507
ARONIS24171
AWD Pharma Brand of Nifedipine
Adalat
Adalat (TN)
Adalat 10
Adalat 20
Adalat 5
Adalat CC
Adalat CR
Adalat Crono
Adalat FT
Adalat Ft
Adalat GITS
Adalat GITS 30
Adalat Gits
Adalat Gits 30
Adalat LA
Adalat LP
Adalat Oros
Adalat PA
Adalat Retard
Adalat XL
Adalate
Adalate LP
Adapine
Adapress
Adcock Ingram Brand of Nifedipine
Adipine XL
Afeditab
Afeditab CR
Afeditab CR (TN)
Alat
Aldipin
Alfadal
Alonix
Alonix S
Alpha-Nifedipine Retard
Angipec
Anifed
Anpine
Apo-Nifed
Aprical
Aprical long
BAY 1040
BAY A 1040
BAY-a 1040
BAYa1040
BCBcMAP01_000046
BIDD:GT0442
BIDD:PXR0034
BIM-0050796.0001
BPBio1_000271
BRN 0497773
BSPBio_000245
BSPBio_001391
BSPBio_002071
Bay-1040
Bay-a-1040
Bay1040
Bayer Brand of Nifedipine
Bio-0733
Bio1_000112
Bio1_000601
Bio1_001090
Bio2_000111
Bio2_000591
Bonacid
C07266
C17H18N2O6
CAS-21829-25-4
CBiol_001826
CCRIS 6074
CHEBI:7565
CHEMBL193
CID4485
CPD000058291
Calcibloc
Calcigard
Calcilat
Camont
Cardifen
Cardilat
Cardionorm
Chronadalate
Chronadalate LP
Chronadalate Lp
Citilat
Coracten
Coracten XL
Coral
Cordafen
Cordaflex
Cordalat
Cordicant
Cordilan
Cordipin
Cordipine
Corinfar
Corotrend
Corynphar
D00437
D009543
DB01115
Depin
Dignokonstant
Dilafed
Dilcor
Dipinkor
DivK1c_000313
Duranifin
EINECS 244-598-3
EU-0100819
Ecodipi
Ecodipin
Ecodipin E
Emaberin
Fedcor
Fedcor Retard
Fenamon
Fenamon SR
Fenamon Sr
Fenigidin
Fenihidin
Fenihidine
Fortipine LA
Glopir
HMS1361F13
HMS1568M07
HMS1791F13
HMS1920P19
HMS1989F13
HMS2051O03
HMS2089H11
HMS2091H20
 
HMS500P15
Hadipin
Hexadilat
I06-0051
I06-1286
IDI1_000313
IDI1_033861
Infedipin
Introcar
KB-1712P
KBio1_000313
KBio2_000111
KBio2_001459
KBio2_002400
KBio2_002679
KBio2_004027
KBio2_004968
KBio2_005247
KBio2_006595
KBio2_007536
KBio3_000221
KBio3_000222
KBio3_001571
KBio3_002879
KBioGR_000111
KBioGR_000627
KBioGR_002400
KBioSS_000111
KBioSS_001459
KBioSS_002405
KRKA Brand of Nifedipine
Kordafen
Korinfar
L001054
LS-1012
Lopac-N-7634
Lopac0_000819
MLS000028521
MLS000758222
MLS001148146
MLS001401371
Macorel
Megalat
MolPort-000-787-707
MolPort-006-822-492
Monohydrochloride, Nifedipine
Myogard
N 7634
N0528
N1fedilat
N7634_SIGMA
NCGC00015748-01
NCGC00015748-02
NCGC00015748-03
NCGC00015748-06
NCGC00015748-13
NCGC00024983-01
NCGC00024983-02
NCGC00024983-03
NCGC00024983-04
NCGC00024983-05
NCGC00024983-06
NCGC00024983-07
NCGC00024983-08
NCGC00091707-01
NINDS_000313
Nedipin
Nicardia
Nifangin
Nifar
Nifdemin
Nifebene
Nifecard
Nifecor
Nifedepat
Nifediac
Nifedical
Nifedical XL
Nifedicor
Nifedin
Nifedine
Nifedipine
Nifedipine (JP15/USP/INN)
Nifedipine Bayer Brand
Nifedipine GTIS
Nifedipine KRKA Brand
Nifedipine Monohydrochloride
Nifedipine Orion Brand
Nifedipine Pfizer Brand
Nifedipine Retard
Nifedipine [USAN:BAN:INN:JAN]
Nifedipine-GTIS
Nifedipino
Nifedipino [INN-Spanish]
Nifedipinum
Nifedipinum [INN-Latin]
Nifedipres
Nifedirex LP
Nifelan
Nifelat
Nifelat Q
Nifelate
Nifensar XL
Nificard
Nifidine
Nifipen
Niphedipine
Oprea1_788617
Orion Brand of Nifedipine
Orix
Oxcord
Pfizer Brand of Nifedipine
Pidilat
Prestwick0_000063
Prestwick1_000063
Prestwick2_000063
Prestwick3_000063
Prestwick_357
Procardia
Procardia (TN)
Procardia XL
S1808_Selleck
SAM001246963
SMR000058291
SPBio_001016
SPBio_002166
SPECTRUM1500431
STK735567
Sepamit
Slofedipine XL
Spectrum2_001058
Spectrum3_000516
Spectrum4_000074
Spectrum5_001278
Spectrum_000979
Tensipine MR
Tibricol
Tocris-1075
UNII-I9ZF7L6G2L
Vascard
ZINC19594578
Zenusin
cMAP_000042
nchembio.95-comp13
nifedipine
34Vasodilator AgentsPhase 13543
35calcium channel blockersPhase 11985
36Tocolytic AgentsPhase 1739
37
Pantoprazoleapproved175102625-70-74679
Synonyms:
102625-70-7
5-(Difluoromethoxy)-2-(((3,4-dimethoxy-2-pyridyl)methyl)sulfinyl)benzimidazole
5-(difluoromethoxy)-2-{[(3,4-dimethoxypyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole
6-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methylsulfinyl]-1H-benzimidazole
AC-679
AC1L1IPJ
Astropan
BIDD:GT0003
BRD-A22380646-001-01-5
BSPBio_002320
BY 1023
BY-1023
C11806
C16H15F2N3O4S
CHEBI:519598
CHEBI:7915
CHEMBL1502
CID4679
D05353
DB00213
HMS1922H20
HMS2090H03
HMS2093F14
HSDB 7292
I06-0068
LS-32883
MolPort-003-666-752
MolPort-005-933-577
NCGC00095188-01
 
NCGC00095188-02
NCGC00095188-03
Pantoloc
Pantopan
Pantoprazol
Pantoprazol [INN-Spanish]
Pantoprazole (USAN/INN)
Pantoprazole Na
Pantoprazole Sodium
Pantoprazole Sodium Hydrate
Pantoprazole [USAN:BAN:INN]
Pantoprazole sodium
Pantoprazolum
Pantoprazolum [INN-Latin]
Pantoprozole
Pantor
Pantozol
Protium
Protonix
Protonix I.V.
Protonix IV
SBB070993
SK&F 96022
SK&F-96022
SK-96022
SKF-96022
SPECTRUM1505818
Somac
TL8000127
UNII-D8TST4O562
pantoprazole
38Hematinics1684
39Trichostatin A5458880-19-6
40
Bilirubin116635-65-45280352
Synonyms:
(4Z,15Z)-Bilirubin IXa
(Z,Z)-Bilirubin IXa
1,10,19,22,23,24-Hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-Biline-8,12-dipropionate
1,10,19,22,23,24-Hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-Biline-8,12-dipropionic acid
2,17-Diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-Biline-8,12-dipropanoate
2,17-Diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-Biline-8,12-dipropanoic acid
3-(2-((3-(2-Carboxyethyl)-4-methyl-5-((3-methyl-5-oxo-4-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-2-yl)methyl)-4-methyl-5-((4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-3-yl)propanoate
3-(2-((3-(2-Carboxyethyl)-4-methyl-5-((3-methyl-5-oxo-4-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-2-yl)methyl)-4-methyl-5-((4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid
 
3-(2-((3-(2-Carboxyethyl)-4-methyl-5-[(Z)-(3-methyl-5-oxo-4-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-1H-pyrrol-2-yl)methyl)-4-methyl-5-[(Z)-(4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene
3-[2-[[3-(2-Carboxyethyl)-5-[(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoate
3-[2-[[3-(2-Carboxyethyl)-5-[(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
3-[2-[[3-(2-Carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(Z)-(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoate
3-[2-[[3-(2-Carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(Z)-(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
Bilirubin
Bilirubin IX-alpha
Cholerythrin
Hematoidin
41Iron SupplementNutraceutical180
42Kavanutraceutical1619000-38-8

Interventional clinical trials:

(show top 50)    (show all 51)
idNameStatusNCT IDPhase
1Evaluation of the Efficacy in Decreasing Iron Absorption in Patients With Congenital Dyserythropoietic Anemia Type I by Treatment With LOSECUnknown statusNCT01795794Phase 4
2Pilot Study for Patients With Poor Response to DeferasiroxCompletedNCT00749515Phase 4
3Efficacy Study of the Use of Sequential DFP-DFO Versus DFPCompletedNCT00733811Phase 4
4Erythrocytapheresis Versus Phlebotomy as Maintenance Therapy in Hereditary Hemochromatosis (HH) PatientsUnknown statusNCT01398644Phase 3
5Haemochromatosis:Phlebotomy Versus Erythrocytapheresis TherapyCompletedNCT00202436Phase 3
6Clinical Management of Hereditary Hemochromatosis: Phlebotomy vs. ErythrocytoapheresisCompletedNCT00440986Phase 2, Phase 3
7Study With Deferiprone and/or Desferrioxamine in Iron Overloaded PatientsCompletedNCT00350662Phase 3
8Efficacy and Safety of the Iron Chelator Deferiprone in Parkinson's DiseaseCompletedNCT00943748Phase 2, Phase 3
9Screening of Hepatocellular Carcinoma in Patients With Compensated CirrhosisCompletedNCT00190385Phase 3
10Stroke With Transfusions Changing to HydroxyureaTerminatedNCT00122980Phase 3
11Safety and Efficacy of Deferasirox (ICL670) in Patients With Iron Overload Resulting From Hereditary HemochromatosisCompletedNCT00395629Phase 1, Phase 2
12Study Using Deferiprone Alone or in Combination With Desferrioxamine in Iron Overloaded Transfusion-dependent PatientsCompletedNCT00349453Phase 2
13Evaluation of Subcutaneous Desferrioxamine as Treatment for Transfusional HemochromatosisCompletedNCT00000595Phase 2
14High-Tc Susceptometer to Monitor Transfusional Iron OverloadCompletedNCT01241357Phase 2
15Treatment of Refractory Hemochromatosis Rheumatism by Anakinra: a Preliminary Phase II StudyRecruitingNCT02263638Phase 2
16Analysis of the Modulation of Serum Hepcidin Level in Response to Iron Oral Intake: Potential Interest for the Differential Diagnosis Between Ferroportin Disease and Dysmetabolic Hepatosiderosis.RecruitingNCT01949467Phase 2
17Trial of Therapeutic Vaccine in Patients With CholangiocarcinomaRecruitingNCT03042182Phase 1, Phase 2
18The Deferasirox-calcium-vitamin D3 Therapy for Postmenopausal Osteoporosis (PMOP)Not yet recruitingNCT02854722Phase 2
19Treatment of Iron Overload With Deferasirox (Exjade) in Hereditary Hemochromatosis and Myelodysplastic SyndromeTerminatedNCT01892644Phase 2
20Oral Nifedipine to Treat Iron OverloadCompletedNCT00712738Phase 1
21Implications for Quality of Life and Quality of Care in Patients With Hereditary HaemochromatosisUnknown statusNCT01991925
22Erythrocyte Apheresis Versus Phlebotomy in HemochromatosisUnknown statusNCT00509652
23Proton Pump Inhibitors in the Prevention of Iron Reaccumulation in Patient With Hereditary HemochromatosisUnknown statusNCT01524757
24Research Network for Neonatal Diseases Induced by Tissular Fetomaternal AlloimmunizationUnknown statusNCT00199628
25HEPFER-Evaluation of a New Phenotypic Biological Marker in Genetic Type 1 HemochromatosisCompletedNCT01784939
26Bone Status on Patients With Genetic Hemochromatosis: a 3 Years Descriptive and Evolutionary StudyCompletedNCT01556360
27Respiratory Variations For Assessing Blood WithdrawalCompletedNCT03066414
28Deferoxamine for the Treatment of HemochromatosisCompletedNCT00001203
29Hemochromatosis--Genetic Prevalence and PenetranceCompletedNCT00006312
30Statistical Basis for Hemochromatosis ScreeningCompletedNCT00005559
31Evaluation of a New MR Pulse Sequence to Quantify Liver Iron ConcentrationCompletedNCT00587535
32Hemochromatosis and Iron Overload Screening Study (HEIRS)CompletedNCT00005541
33Mi-iron - Moderately Increased Iron - is Reducing Iron Overload Necessary?CompletedNCT01631708
34Iron Overload in African AmericansCompletedNCT00001455
35Impact of Host Iron Status and Iron Supplement Use on Erythrocytic Stage of Plasmodium FalciparumCompletedNCT01027663
36Risk Factors of Porphyria Cutanea Tarda (PCT)CompletedNCT00213772
37Study of the Pathogenesis of Porphyria Cutanea TardaCompletedNCT00005103
38Iron Supplement Effect on Child DevelopmentCompletedNCT02690675
39Ischemia Modified Albumin (IMA) Expression in the Male and Female PopulationCompletedNCT02894671
40Iron Overload in Stem Cell Transplant RecipientsCompletedNCT00806715
41Treatment of HemochromatosisRecruitingNCT00007150
42Estimation of Myocardial Iron Overload by 3 Tesla MRI in HFE Hereditary HaemochromatosisRecruitingNCT02099214
43Impact of Bloodletting on Iron Metabolism in Type 1 HemochromatosisRecruitingNCT01810965
44Confounder-Corrected Quantitative MRI Biomarker of Hepatic Iron ContentRecruitingNCT02025543
45China Registry for Genetic / Metabolic Liver DiseasesRecruitingNCT03131427
46Evaluation of Patients With Liver DiseaseRecruitingNCT00001971
47The Nor-Hand StudyRecruitingNCT03083548
48Massive Iron Deposit AssessmentRecruitingNCT01572922
49Liver Fibrosis in Sickle Cell DiseaseRecruitingNCT02007746
50Cardiac Function in Patients With Hereditary HemochromatosisActive, not recruitingNCT00068159

Search NIH Clinical Center for Hemochromatosis

Inferred drug relations via UMLS68/NDF-RT46:


Cochrane evidence based reviews: hemochromatosis

Genetic Tests for Hemochromatosis

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Genetic tests related to Hemochromatosis:

id Genetic test Affiliating Genes
1 Hemochromatosis Type 127
2 Hereditary Hemochromatosis27

Anatomical Context for Hemochromatosis

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MalaCards organs/tissues related to Hemochromatosis:

36
Liver, Heart, Pancreas, Skin, Testes, Lung, Bone

Publications for Hemochromatosis

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Articles related to Hemochromatosis:

(show top 50)    (show all 1310)
idTitleAuthorsYear
1
The hemochromatosis protein HFE 20 years later: An emerging role in antigen presentation and in the immune system. (28474781)
2017
2
Relevance of C5b9 immunostaining in the diagnosis of neonatal hemochromatosis. (28085791)
2017
3
Properties of donated red blood cell components from patients with hereditary hemochromatosis. (27807848)
2017
4
Iron related hemochromatosis (HFE) gene mutations in Friedreich Ataxia patients. (27814974)
2017
5
Hereditary hemochromatosis arthropathy and Doppler ultrasound findings of synovitis. (28371912)
2017
6
Diabetes mellitus caused by secondary hemochromatosis after multiple blood transfusions in 2 patients with severe aplastic anemia. (28443261)
2017
7
Characterization of ferroptosis in murine models of hemochromatosis. (28195347)
2017
8
Is DNA testing for hemochromatosis diagnosis reliable? (28092202)
2017
9
Porphyria Cutanea Tarda as the Initial Manifestation of Subclinical Hereditary Hemochromatosis. (28479501)
2017
10
GNPAT rs11558492 is not a Major Modifier of Iron Status: Study of Italian Hemochromatosis Patients and Blood Donors. (28425416)
2017
11
Iron Overload in the Liver of 2 Children: Nonalcoholic Steatohepatitis and Juvenile Hemochromatosis. (28067690)
2017
12
Levodopa Responsive Parkinsonism in Patients with Hemochromatosis: Case Presentation and Literature Review. (28424751)
2017
13
Identification of hereditary hemochromatosis pedigrees and a novel SLC40A1 mutation in Chinese population. (28110135)
2017
14
ASSESSMENT OF DRUSEN AND OTHER RETINAL DEGENERATIVE CHANGES IN PATIENTS WITH HEREDITARY HEMOCHROMATOSIS. (28291154)
2017
15
Juvenile hemochromatosis and hepatocellular carcinoma in a patient with a novel mutation in the HJV gene. (28363629)
2017
16
Secondary Hemochromatosis due to Chronic Oral Iron Supplementation. (28133557)
2017
17
Worse Outcomes of Patients With HFE Hemochromatosis With Persistent Increases in Transferrin Saturation During Maintenance Therapy. (28111337)
2017
18
Diabetes in HFE Hemochromatosis. (28331855)
2017
19
Neonatal Hemochromatosis: Blitz Diagnosis Results in Favorable Outcome. (28161201)
2017
20
Hemochromatosis, Erythrocytosis and the JAK2 p.V617F Mutation. (28439222)
2017
21
A Case Study of Hemochromatosis and Conflicting Point Shear Wave Measurements in the Assessment of Liver Fibrosis. (28081023)
2017
22
R2*-relaxometry of the pancreas in patients with human hemochromatosis protein associated hereditary hemochromatosis. (28267532)
2017
23
Human Hemochromatosis Protein (HFE) Immunoperoxidase Stain Highlights Choriocarcinoma within Mixed Germ Cell Tumors. (27034532)
2016
24
Molecular pathogenesis of hereditary hemochromatosis. (27031690)
2016
25
The evolutionary adaptation of hemochromatosis associated mutations during the neolithic. (27348451)
2016
26
Effect of Hereditary Hemochromatosis Gene (HFE) H63D and C282Y Mutations on Iron Overload in Sickle Cell Disease Patients. (27095682)
2016
27
Movement Disorders Associated With Hemochromatosis. (27827297)
2016
28
Management of human factors engineering-associated hemochromatosis: A 2015 update. (27004087)
2016
29
Effect of the Hemochromatosis Mutations on Iron Overload among the Indian I^ Thalassemia Carriers. (27561698)
2016
30
Proprotein convertase 7 rs236918 is associated with liver fibrosis in Italian patients with HFE-related Hemochromatosis. (26868056)
2016
31
A GNPAT variant (D519G) is not associated with an elevated serum ferritin or iron removed by phlebotomy in patients referred for C282Y-linked hemochromatosis. (27740525)
2016
32
Accepting hereditary hemochromatosis blood donors: ask not why, ask why not. (27933629)
2016
33
Frequency of Hereditary Hemochromatosis (HFE) Gene Mutations in Egyptian Beta Thalassemia Patients and its Relation to Iron Overload. (27335591)
2016
34
Hemochromatosis gene mutations may affect the survival of patients with myelodysplastic syndrome. (27077775)
2016
35
An immunohistochemical study of placental syncytiotrophoblasts in neonatal hemochromatosis. (27871472)
2016
36
Identification of novel mutations in HFE, HFE2, TfR2, and SLC40A1 genes in Chinese patients affected by hereditary hemochromatosis. (27896572)
2016
37
Successful Treatment of Iron-Overload Cardiomyopathy in Hereditary Hemochromatosis With Deferoxamine and Deferiprone. (27789107)
2016
38
Hereditary hemochromatosis: Dealing with iron overload. (27032055)
2016
39
Structural basis of urea-induced unfolding: Unraveling the folding pathway of hemochromatosis factor E. (27339324)
2016
40
Effect of pH on the Stability of Hemochromatosis Factor E: A Combined Spectroscopic and Molecular Dynamics Simulation Based Study. (27174123)
2016
41
Secondary hemochromatosis as a result of acute transfusion-induced iron overload in a burn patient. (27574680)
2016
42
Living Related Liver Transplantation in an Infant with Neonatal Hemochromatosis. (27437193)
2016
43
Course of iron parameters in HFE-hemochromatosis patients during initial treatment with erythrocytapheresis compared to phlebotomy. (26878994)
2016
44
PIEZO1 gene mutation in a Japanese family with hereditary high phosphatidylcholine hemolytic anemia and hemochromatosis-induced diabetes mellitus. (26971963)
2016
45
Dental pigmentation and hemochromatosis: A case report. (27981269)
2016
46
Severe Myocardial Dysfunction Reversed by Iron-Chelation Therapy in an Asian Patient with Hereditary Hemochromatosis. (27140717)
2016
47
Blood removal therapy in hereditary hemochromatosis induces a stress response resulting in improved genome integrity. (27045387)
2016
48
HAMP Gene Mutation Associated with Juvenile Hemochromatosis in Brazilian Patients. (27007796)
2016
49
Increased Retinal Expression of the Pro-Angiogenic Receptor GPR91 via BMP6 in a Mouse Model of Juvenile Hemochromatosis. (27046124)
2016
50
Neonatal hemochromatosis in monochorionic twins. (26836824)
2016

Variations for Hemochromatosis

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UniProtKB/Swiss-Prot genetic disease variations for Hemochromatosis:

70 (show all 12)
id Symbol AA change Variation ID SNP ID
1HFEp.Ser65CysVAR_004397rs1800730
2HFEp.Cys282TyrVAR_004398rs1800562
3HFEp.Gln127HisVAR_008113rs28934595
4HFEp.Arg330MetVAR_008114rs111033558
5HFEp.Gly93ArgVAR_008729rs28934597
6HFEp.Ile105ThrVAR_008730rs28934596
7HFEp.Gln283ProVAR_037304rs111033563
8HFEp.Arg6SerVAR_042506rs149342416
9HFEp.Gly43AspVAR_042507
10HFEp.Arg66CysVAR_042508rs747739169
11HFEp.Arg224GlyVAR_042510
12HFEp.Val295AlaVAR_042511rs143175221

Clinvar genetic disease variations for Hemochromatosis:

5 (show all 15)
id Gene Variation Type Significance SNP ID Assembly Location
1HFENM_ 000410.3(HFE): c.314T> C (p.Ile105Thr)SNVPathogenicrs28934596GRCh37Chr 6, 26091306: 26091306
2HFENM_ 000410.3(HFE): c.277G> C (p.Gly93Arg)SNVPathogenicrs28934597GRCh37Chr 6, 26091269: 26091269
3HFENM_ 000410.3(HFE): c.381A> C (p.Gln127His)SNVPathogenicrs28934595GRCh37Chr 6, 26091582: 26091582
4HFENM_ 000410.3(HFE): c.989G> T (p.Arg330Met)SNVPathogenicrs111033558GRCh37Chr 6, 26093443: 26093443
5HAMPNM_ 021175.3(HAMP): c.216C> A (p.Cys72Ter)SNVPathogenicrs763369315GRCh38Chr 19, 35285003: 35285003
6TFR2NM_ 003227.3(TFR2): c.2033G> C (p.Arg678Pro)SNVLikely pathogenicrs786204108GRCh37Chr 7, 100224489: 100224489
7HFENM_ 000410.3(HFE): c.848A> C (p.Gln283Pro)SNVPathogenicrs111033563GRCh37Chr 6, 26093144: 26093144
8HFENM_ 000410.3(HFE): c.506G> A (p.Trp169Ter)SNVPathogenicrs797045145GRCh37Chr 6, 26091707: 26091707
9HFE2NM_ 213653.3(HFE2): c.959G> T (p.Gly320Val)SNVPathogenicrs74315323GRCh37Chr 1, 145416614: 145416614
10HFE2NM_ 213653.3(HFE2): c.963C> A (p.Cys321Ter)SNVPathogenicrs121434374GRCh37Chr 1, 145416618: 145416618
11HFENM_ 000410.3(HFE): c.892G> T (p.Glu298Ter)SNVPathogenicrs749553271GRCh38Chr 6, 26092960: 26092960
12HFENM_ 000410.3(HFE): c.546_ 547delCC (p.Leu183Glyfs)deletionPathogenicrs765804978GRCh38Chr 6, 26091519: 26091520
13HAMPNM_ 021175.3(HAMP): c.212G> A (p.Gly71Asp)SNVrisk factorrs104894696GRCh37Chr 19, 35775902: 35775902
14TFR2NM_ 003227.3(TFR2): c.1364G> A (p.Arg455Gln)SNVrisk factorrs41303501GRCh37Chr 7, 100226902: 100226902
15HFENM_ 000410.3(HFE): c.502G> T (p.Glu168Ter)SNVPathogenicrs146519482GRCh38Chr 6, 26091475: 26091475

Expression for genes affiliated with Hemochromatosis

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Search GEO for disease gene expression data for Hemochromatosis.

Pathways for genes affiliated with Hemochromatosis

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Pathways related to Hemochromatosis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
110.1HAMP, HFE, HFE2
2
Show member pathways
10.0BMP2, HFE2, UBE2D1
39.9CP, TF, TFRC
4
Show member pathways
9.7CP, HEPH, SLC11A2, SLC40A1
5
Show member pathways
9.6CP, FXN, HEPH, UROD
69.3CP, FTL, SLC11A2, SLC40A1, TF, TFRC
79.3ACO1, HAMP, SLC11A2, SLC40A1, TF, TFR2
89.3CYBRD1, FTL, HEPH, SLC11A2, SLC40A1, TF
9
Show member pathways
8.9CP, CYBRD1, FTL, HEPH, SLC11A2, SLC40A1
10
Show member pathways
8.9CP, CYBRD1, FTL, HEPH, SLC11A2, SLC40A1

GO Terms for genes affiliated with Hemochromatosis

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Cellular components related to Hemochromatosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1BMP receptor complexGO:007072411.0BMP2, HFE2
2basal part of cellGO:004517810.8HFE, SLC11A2, TF
3external side of plasma membraneGO:000989710.6B2M, HFE, TFR2, TFRC
4cytoplasmic vesicleGO:003141010.4HFE, SLC11A2, TF, TFR2, TFRC
5MHC class I protein complexGO:004261210.3B2M, HFE, HLA-B, MR1
6HFE-transferrin receptor complexGO:199071210.2B2M, HFE, HFE2, TF, TFR2, TFRC
7perinuclear region of cytoplasmGO:004847110.1HEPH, HFE, SLC11A2, TF, TFRC
8cell surfaceGO:000998610.0B2M, BMP2, HFE2, HLA-B, SLC11A2, TF
9extracellular spaceGO:00056159.9B2M, BMP2, CP, HAMP, HFE, HFE2
10recycling endosomeGO:00550379.8HFE, SLC11A2, TF, TFRC

Biological processes related to Hemochromatosis according to GeneCards Suite gene sharing:

(show all 30)
idNameGO IDScoreTop Affiliating Genes
1ferrous iron import across plasma membraneGO:009870710.8TF, TFR2
2ferrous iron import into cellGO:009746010.8TF, TFR2
3acute-phase responseGO:000695310.8HAMP, HFE, TFR2
4positive regulation of peptide hormone secretionGO:009027710.8HFE, TFR2
5iron ion transmembrane transportGO:003475510.7SLC11A2, SLC40A1
6negative regulation of receptor bindingGO:190012110.7B2M, HFE
7positive regulation of ferrous iron bindingGO:190443410.7B2M, HFE
8positive regulation of ferrous iron import across plasma membraneGO:190444010.7B2M, HFE
9positive regulation of ferrous iron import into cellGO:190399110.7B2M, HFE
10antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independentGO:000248010.7B2M, HLA-B
11positive regulation of receptor bindingGO:190012210.7B2M, HFE
12porphyrin-containing compound biosynthetic processGO:000677910.6SLC11A2, UROD
13positive regulation of transferrin receptor bindingGO:190443710.6B2M, HFE
14response to iron ion starvationGO:199064110.6HAMP, HFE
15copper ion transportGO:000682510.6CP, HEPH, SLC11A2
16antigen processing and presentationGO:001988210.6HFE, HLA-B, MR1
17protein autoprocessingGO:001654010.5FXN, HFE2
18positive regulation of protein bindingGO:003209210.5B2M, BMP2, HFE
19BMP signaling pathwayGO:003050910.5BMP2, HFE, HFE2, UBE2D1
20heme biosynthetic processGO:000678310.5FXN, SLC11A2, UROD
21cellular response to iron ionGO:007128110.5B2M, HFE, TF, TFR2
22positive regulation of receptor-mediated endocytosisGO:004826010.5B2M, HFE, TF
23multicellular organismal iron ion homeostasisGO:006058610.5HAMP, HFE, SLC11A2, SLC40A1
24antigen processing and presentation of peptide antigen via MHC class IGO:000247410.4B2M, HFE, HLA-B, MR1
25response to iron ionGO:00100399.9CYBRD1, FXN, HAMP, HFE, SLC11A2, TFR2
26transferrin transportGO:00335729.9HFE, TF, TFR2, TFRC
27ion transportGO:00068119.8CP, FXN, HEPH, HFE, SLC11A2, SLC40A1
28iron ion transportGO:00068269.7B2M, FTL, HEPH, SLC11A2, SLC40A1, TF
29iron ion homeostasisGO:00550729.2B2M, FTL, FXN, HEPH, HFE, HFE2
30cellular iron ion homeostasisGO:00068798.6ACO1, CP, CYBRD1, FTL, FXN, HAMP

Molecular functions related to Hemochromatosis according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1ferrous iron transmembrane transporter activityGO:001509311.0SLC11A2, SLC40A1
2iron ion transmembrane transporter activityGO:000538111.0SLC11A2, SLC40A1
3co-receptor bindingGO:003970610.9BMP2, HFE, TFR2
4ferrous iron bindingGO:000819810.6FXN, HEPH, TF
5glycoprotein bindingGO:000194810.6B2M, HFE2, TFR2, TFRC
6ferroxidase activityGO:000432210.6CP, FXN, HEPH
7ferric iron bindingGO:000819910.6FTL, FXN, TF
8transferrin receptor activityGO:000499810.4TFR2, TFRC
9transferrin receptor bindingGO:199045910.0HFE, HFE2, TF
10protein bindingGO:00055157.4ACO1, B2M, BMP2, CYBRD1, FTL, FXN

Sources for Hemochromatosis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
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30ICD10
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32ICD9CM
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34KEGG
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40MESH via Orphanet
41MGI
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67Tumor Gene Family of Databases
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69UMLS via Orphanet