MCID: HMG022
MIFTS: 19

Hemoglobin C - Beta-Thalassemia malady

Blood diseases, Rare diseases categories

Summaries for Hemoglobin C - Beta-Thalassemia

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34MalaCards
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MalaCards: Hemoglobin C - Beta-Thalassemia, also known as thalassemia-hemoglobin c disease, is related to beta thalassemia and thalassemia, and has symptoms including splenomegaly, anaemia and microcytic anemia. An important gene associated with Hemoglobin C - Beta-Thalassemia is HBB (hemoglobin, beta). Affiliated tissues include myeloid.

Aliases & Classifications for Hemoglobin C - Beta-Thalassemia

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50Orphanet, 63UMLS, 27ICD10 via Orphanet, 60SNOMED-CT via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Blood diseases


Characteristics (Orphanet epidemiological data):

50
hemoglobin c - beta-thalassemia:
Inheritance: Autosomal recessive


Aliases & Descriptions:

hemoglobin c - beta-thalassemia 50
thalassemia-hemoglobin c disease 63
hbc - beta-thalassemia 50
c-beta-thalassemia 50


External Ids:

ICD10 via Orphanet27 D58.2
SNOMED-CT via Orphanet60 61777009

Related Diseases for Hemoglobin C - Beta-Thalassemia

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18GeneCards, 19GeneDecks
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Diseases in the Hemoglobin E - Beta-Thalassemia family:

hemoglobin c - beta-thalassemia

Diseases related to Hemoglobin C - Beta-Thalassemia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1beta thalassemia10.7
2thalassemia10.7
3sarcoidosis10.3

Symptoms for Hemoglobin C - Beta-Thalassemia

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50Orphanet
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Symptoms:

50
  • splenomegaly
  • anaemia
  • microcytic anemia
  • hemoglobinosis/hemoglobinopathy

Drugs & Therapeutics for Hemoglobin C - Beta-Thalassemia

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Hemoglobin C - Beta-Thalassemia

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Anatomical Context for Hemoglobin C - Beta-Thalassemia

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34MalaCards
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MalaCards organs/tissues related to Hemoglobin C - Beta-Thalassemia:

34
Myeloid

Animal Models for Hemoglobin C - Beta-Thalassemia or affiliated genes

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Publications for Hemoglobin C - Beta-Thalassemia

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53PubMed
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Articles related to Hemoglobin C - Beta-Thalassemia:

idTitleAuthorsYear
1
Fatal splenic rupture in a pregnant woman with hemoglobin C/beta-thalassemia and myeloid metaplasia. (16879031)
2006
2
Red cell osmotic fragility studies in hemoglobin C-beta thalassemia: osmotically resistant microspherocytes. (14641140)
2003
3
Hemoglobin C/beta+ thalassemia and sarcoidosis. (7485093)
1995
4
Double heterozygosis for hemoglobin C-beta thalassemia: description of a Spanish family. Hemoglobin C-beta thalassemia in a Spanish family. (639336)
1978

Variations for Hemoglobin C - Beta-Thalassemia

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Expression for genes affiliated with Hemoglobin C - Beta-Thalassemia

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hemoglobin C - Beta-Thalassemia

Search GEO for disease gene expression data for Hemoglobin C - Beta-Thalassemia.

Pathways for genes affiliated with Hemoglobin C - Beta-Thalassemia

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Compounds for genes affiliated with Hemoglobin C - Beta-Thalassemia

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GO Terms for genes affiliated with Hemoglobin C - Beta-Thalassemia

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Products for genes affiliated with Hemoglobin C - Beta-Thalassemia

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Hemoglobin C - Beta-Thalassemia

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet