MCID: HMG001
MIFTS: 28

Hemoglobin C Disease malady

Blood diseases category

Summaries for Hemoglobin C Disease

About this section
Sources:
63Wikipedia, 32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:63 Hemoglobin C (abbreviated as Hb C or HbC) is an abnormal hemoglobin in which substitution of a glutamic... more...

MalaCards: Hemoglobin C Disease, also known as hb c disease, is related to sickle cell anemia and splenic disease. An important gene associated with Hemoglobin C Disease is HBB (hemoglobin, beta). Affiliated tissues include spleen, bone and bone marrow.

Aliases & Classifications for Hemoglobin C Disease

About this section
Sources:
8Disease Ontology, 42NIH Rare Diseases, 48Orphanet, 60UMLS, 34MeSH, 39NCIt, 56SNOMED-CT, 35MESH via Orphanet, 26ICD10 via Orphanet, 57SNOMED-CT via Orphanet, 61UMLS via Orphanet
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Blood diseases


Characteristics (Orphanet epidemiological data):

48
hemoglobin c disease:
Inheritance: Autosomal recessive; Age of onset: Variable; Age of death: Normal


Aliases & Descriptions:

hemoglobin c disease 8 42 48 60
hb c disease 42 60
hb-c disease 8


External Ids:

Disease Ontology8 DOID:2859
MeSH34 D006445
NCIt39 C34675
MESH via Orphanet35 D006445
SNOMED-CT56 51053007
ICD10 via Orphanet26 D58.2
SNOMED-CT via Orphanet57 51053007
UMLS via Orphanet61 C0019021

Related Diseases for Hemoglobin C Disease

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Hemoglobin C Disease:



Diseases related to hemoglobin c disease

Clinical Features for Hemoglobin C Disease

About this section

Drugs & Therapeutics for Hemoglobin C Disease

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Hemoglobin C Disease

Drug clinical trials:

Search ClinicalTrials for Hemoglobin C Disease

Search NIH Clinical Center for Hemoglobin C Disease

Search CenterWatch for Hemoglobin C Disease

Genetic Tests for Hemoglobin C Disease

About this section

Anatomical Context for Hemoglobin C Disease

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Hemoglobin C Disease:

32
Spleen, Bone, Bone marrow

Animal Models for Hemoglobin C Disease or affiliated genes

About this section

Publications for Hemoglobin C Disease

About this section
Sources:
50PubMed
See all sources

Articles related to Hemoglobin C Disease:

(show top 50)    (show all 96)
idTitleAuthorsYear
1
Severe proliferative retinopathy is associated with blood hyperviscosity in sickle cell hemoglobin-C disease but not in sickle cell anemia. (23076002)
2013
2
Homozygous hemoglobin C disease. (24137818)
2013
3
Paravertebral mass in a patient with hemoglobin C disease. (21602071)
2011
4
Red blood cell aggregation, aggregate strength and oxygen transport potential of blood are abnormal in both homozygous sickle cell anemia and sickle-hemoglobin C disease. (19644138)
2009
5
Acute splenic sequestration crisis in adults with hemoglobin S-C disease: a report of nine cases. (16463155)
2006
6
Hemoglobin C disease. (15470225)
2004
7
Sickle cell hemoglobin C disease in Saudi Arabia. (12682691)
2003
8
Intrathoracic extramedullary hematopoietic tumor in hemoglobin C disease. (9140302)
1997
9
Intrathoracic extramedullary hematopoietic tumor in hemoglobin C disease. (9140301)
1997
10
Acute splenic complications in children with sickle cell-hemoglobin C disease. (9202620)
1997
11
Evolution of a retinal hemorrhage in a patient with sickle cell-hemoglobin C disease. (7639661)
1995
12
Retrospective diagnosis of sickle cell-hemoglobin C disease and parvovirus infection by molecular DNA analysis of postmortem tissue. (8522312)
1995
13
Iron deficiency and hemoglobin C disease. (7608805)
1995
14
Thrombotic thrombocytopenic purpura associated with sickle cell-hemoglobin C disease. (7973909)
1994
15
Hemoglobin C disease in infancy and childhood. (7965426)
1994
16
Concurrent sickle cell hemoglobin C disease and diabetes mellitus: no added risk of proliferative retinopathy? (7966431)
1994
17
The obstetric performance of sickle cell disease patients and homozygous hemoglobin C disease patients in Ile-Ife, Nigeria. (1351002)
1992
18
Acute renal failure in a patient with essential thrombocythemia, diabetes mellitus, and heterozygous hemoglobin C disease. (2300836)
1990
19
Splenic infarction at low altitude in a child with hemoglobin S-C disease. (3042248)
1988
20
Regulation of cation content and cell volume in hemoglobin erythrocytes from patients with homozygous hemoglobin C disease. (3998150)
1985
21
Mild splenic sequestration crises in sickle-hemoglobin C disease. (6723180)
1984
22
Sickle-cell hemoglobin C disease in pregnancy: report of a case with review of the literature. (7380681)
1980
23
Sickle cell and sickle cell-hemoglobin C disease during pregnancy. (5049901)
1972
24
Fractionation studies of copper in erythrocytes from normal, sickle cell anemia, and hemoglobin C disease. (5423505)
1970
25
Homozygous hemoglobin C disease: Clinical review of fifteen patients. (5643614)
1968
26
Pathogenesis of hemolytic anemia in homozygous hemoglobin C disease. (6061750)
1967
27
Thalassemia--hemoglobin C disease in white siblings. (5989222)
1966
28
THE COEXISTENCE OF ACUTE RHEUMATIC FEVER AND SICKLE CELL-HEMOGLOBIN C DISEASE. (14247521)
1965
29
INTRAERYTHROCYTIC HEMOGLOBIN CRYSTALS IN SICKLE CELL-HEMOGLOBIN C DISEASE. (14267697)
1965
30
HEMOGLOBIN C DISEASE. QUANTITATIVE DETERMINATION OF IRON KINETICS AND HEMOGLOBIN SYNTHESIS. (14158490)
1964
31
SICKLE CELL--HEMOGLOBIN C DISEASE. (14208415)
1964
32
Roentgenographic and clinical appraisal of sickle cell-hemoglobin C disease. (14491713)
1962
33
Hemoglobin C disease in an Anglo-Saxon family. (13826023)
1960
34
Sickle cell hemoglobin-C disease treated by splenectomy. (13835649)
1960
35
Pulmonary infarction and atrophy of the spleen associated with sickle-cell hemoglobin C disease. (13657308)
1959
36
Hemolytic studies in homozygous hemoglobin C disease. (13661102)
1959
37
Sickle cell-hemoglobin C disease and pregnancy, including a case of osteomyelitis. (13649807)
1959
38
Pregnancy in sickle cell, anemia, sickle cell-hemoglobin C disease, and variants thereof. (13649805)
1959
39
Sickle cell-hemoglobin C disease; clinical, laboratory, and anatomic findings. (13655599)
1959
40
The clinical manifestations of sickle cell-hemoglobin C disease and sickle cell anemia. (13556166)
1958
41
Vitreous hemorrhage associated with sickle-cell trait and sickle-cell hemoglobin-C disease. (13533498)
1958
42
Bone marrow and fat embolism in sickle cell anemia and sickle cell-hemoglobin C disease. (13560993)
1958
43
Homozygous hemoglobin C disease; relation to military service. (13422753)
1957
44
Clinical and necropsy findings in hemoglobin C disease. (13382991)
1957
45
Homozygous hemoglobin C disease; report of a case. (13408449)
1957
46
Thalassemia-hemoglobin C disease in white siblings. (13322518)
1956
47
Homozygous hemoglobin C disease; report of a case with studies on the pathophysiology and neonatal formation of hemoglobin C. (14361465)
1955
48
Hemoglobin C disease: report of four cases. (14351246)
1955
49
Hemoglobin C disease in identical twins. (14376393)
1955
50
Studies on abnormal hemoglobins. IX. Pure (homozygous) hemoglobin C disease. (13208754)
1954

Genetic Variations for Hemoglobin C Disease

About this section

Expression for genes affiliated with Hemoglobin C Disease

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Hemoglobin C Disease

Search GEO for disease gene expression data for Hemoglobin C Disease.

Pathways for genes affiliated with Hemoglobin C Disease

About this section

Compounds for genes affiliated with Hemoglobin C Disease

About this section

GO Terms for genes affiliated with Hemoglobin C Disease

About this section

Products for genes affiliated with Hemoglobin C Disease

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Hemoglobin C Disease

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet