MCID: HMG016
MIFTS: 13

Hemoglobin Sd malady

Blood category

Summaries for Hemoglobin Sd

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33MalaCards
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MalaCards: Hemoglobin Sd is related to sickle cell disease and thalassemia. An important gene associated with Hemoglobin Sd is HBB (hemoglobin, beta), and among its related pathways are Platelet activation, signaling and aggregation and Factors involved in megakaryocyte development and platelet production. The compounds oxygen and heme have been mentioned in the context of this disorder.

Aliases & Classifications for Hemoglobin Sd

Sources:
20GeneTests
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Blood


Aliases & Descriptions:

hemoglobin sd 20


Related Diseases for Hemoglobin Sd

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Hemoglobin Sd via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 12)
idRelated DiseaseScoreTop Affiliating Genes
1sickle cell disease30.4HBB, HBD
2thalassemia30.1HBB, HBD
3hemoglobin d disease10.6
4hemoglobin c disease10.5
5sickle cell - hemoglobin d disease10.3
6sickle cell - hemoglobin c disease10.3
7moyamoya disease10.1
8hemoglobin e disease10.1
9cholelithiasis10.1
10malaria10.0HBB
11sickle cell anemia10.0HBB, HBD
12deficiency anemia10.0HBB, HBD

Graphical network of diseases related to Hemoglobin Sd:



Diseases related to hemoglobin sd

Clinical Features for Hemoglobin Sd

Drugs & Therapeutics for Hemoglobin Sd

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Hemoglobin Sd

Drug clinical trials:

Search ClinicalTrials for Hemoglobin Sd

Search NIH Clinical Center for Hemoglobin Sd

Search CenterWatch for Hemoglobin Sd

Genetic Tests for Hemoglobin Sd

Sources:
20GeneTests
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Genetic tests related to Hemoglobin Sd:

id Genetic test Affiliating Genes
1 Hemoglobin Sd20 HBB

Anatomical Context for Hemoglobin Sd

Animal Models for Hemoglobin Sd or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Hemoglobin Sd

Genetic Variations for Hemoglobin Sd

Expression for genes affiliated with Hemoglobin Sd

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hemoglobin Sd

Search GEO for disease gene expression data for Hemoglobin Sd.

Pathways for genes affiliated with Hemoglobin Sd

Sources:
54Reactome
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Pathways related to Hemoglobin Sd according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.1HBB, HBD
29.1HBB, HBD

Compounds for genes affiliated with Hemoglobin Sd

Sources:
45Novoseek, 24HMDB, 29IUPHAR, 11DrugBank
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Compounds related to Hemoglobin Sd according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1oxygen45 2410.1HBB, HBD
2heme29 11 2410.8HBB, HBD

GO Terms for genes affiliated with Hemoglobin Sd

Sources:
16Gene Ontology
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Cellular components related to Hemoglobin Sd according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1hemoglobin complexGO:0058339.1HBB, HBD

Biological processes related to Hemoglobin Sd according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1blood coagulationGO:0075969.1HBB, HBD

Molecular functions related to Hemoglobin Sd according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1oxygen transporter activityGO:0053449.1HBB, HBD
2iron ion bindingGO:0055069.1HBB, HBD
3oxygen bindingGO:0198259.0HBB, HBD
4heme bindingGO:0200378.8HBB, HBD

Products for genes affiliated with Hemoglobin Sd

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Hemoglobin Sd

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet