MCID: HMG010
MIFTS: 23

Hemoglobinemia malady

Blood diseases category

Summaries for Hemoglobinemia

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Sources:
63Wikipedia, 32MalaCards
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Wikipedia:63 Hemoglobinemia (British Haemoglobinaemia) is a medical condition in which there is an excess of... more...

MalaCards: Hemoglobinemia, also known as haemoglobinemia, is related to hemolytic anemia and sickle cell anemia. An important gene associated with Hemoglobinemia is HP (haptoglobin), and among its related pathways is Binding and Uptake of Ligands by Scavenger Receptors. The compounds cellulose acetate and vitamin b12 have been mentioned in the context of this disorder. Related mouse phenotype liver/biliary system.

Aliases & Classifications for Hemoglobinemia

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Sources:
42NIH Rare Diseases, 44Novoseek, 60UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Blood diseases


Aliases & Descriptions:

hemoglobinemia 42 44 60
haemoglobinemia 42


Related Diseases for Hemoglobinemia

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Hemoglobinemia:



Diseases related to hemoglobinemia

Clinical Features for Hemoglobinemia

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Drugs & Therapeutics for Hemoglobinemia

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Hemoglobinemia

Drug clinical trials:

Search ClinicalTrials for Hemoglobinemia

Search NIH Clinical Center for Hemoglobinemia

Search CenterWatch for Hemoglobinemia

Genetic Tests for Hemoglobinemia

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Anatomical Context for Hemoglobinemia

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Animal Models for Hemoglobinemia or affiliated genes

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Sources:
36MGI
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MGI Mouse Phenotypes related to Hemoglobinemia:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.5HP, HBB, B2M

Publications for Hemoglobinemia

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Genetic Variations for Hemoglobinemia

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Expression for genes affiliated with Hemoglobinemia

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hemoglobinemia

Search GEO for disease gene expression data for Hemoglobinemia.

Pathways for genes affiliated with Hemoglobinemia

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53Reactome
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Pathways related to Hemoglobinemia according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
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9.0HP, HBB

Compounds for genes affiliated with Hemoglobinemia

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Sources:
44Novoseek, 49PharmGKB, 11DrugBank, 24HMDB, 2BitterDB, 28IUPHAR
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Compounds related to Hemoglobinemia according to GeneCards/GeneDecks:

(show all 29)
idCompoundScoreTop Affiliating Genes
1cellulose acetate449.7HP, B2M
2vitamin b12449.7HP, B2M
3neopterin449.7HP, B2M
4rituximab44 49 1111.7B2M, HP
5uric acid44 2410.6HP, B2M
6chloroquine44 2 49 28 1113.6B2M, HP
7vitamin-e449.6HP, B2M
8urea44 11 2411.6HP, B2M
9thyroxine44 2410.5HP, B2M
10hyaluronic acid44 2410.5B2M, HP
11porphobilinogen44 11 2411.5HBB, B2M
12folate449.5HP, B2M
1323-diphosphoglycerate449.4HP, HBB
14benzidine449.4HP, HBB
15hind iii449.4HP, HBB
16sucrose44 11 2411.3B2M, HP
17glucose 6-phosphate44 2410.3HP, HBB
18valine449.2HBB, B2M
19vitamin a44 11 2411.2B2M, HP
20glyceraldehyde 3-phosphate449.2HBB, B2M
21polyacrylamide449.0HP, HBB
22iron44 249.9B2M, HBB, HP
23lactate448.9HP, HBB, B2M
24aspartate448.9B2M, HBB, HP
25steroid448.9HP, HBB, B2M
26alanine448.8HP, HBB, B2M
27estrogen448.8HP, HBB, B2M
28cysteine448.7B2M, HBB, HP
29serine448.2HP, HBB, B2M

GO Terms for genes affiliated with Hemoglobinemia

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Sources:
16Gene Ontology
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Cellular components related to Hemoglobinemia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1haptoglobin-hemoglobin complexGO:0318388.9HP, HBB
2endocytic vesicle lumenGO:0716828.7HP, HBB
3extracellular regionGO:0055768.5HP, HBB, B2M

Biological processes related to Hemoglobinemia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to hydrogen peroxideGO:0425429.0HP, HBB
2positive regulation of cell deathGO:0109428.7HP, HBB

Molecular functions related to Hemoglobinemia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1hemoglobin bindingGO:0304929.0HP, HBB

Products for genes affiliated with Hemoglobinemia

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Hemoglobinemia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet