Hemolytic-Uremic Syndrome disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical Trials

NIH Rare Diseases:⁴⁵ Hemolytic uremic syndrome (hus) is a disorder that usually occurs when an e. coli bacterial infection in the digestive system produces toxic substances that destroy red blood cells. symptoms include vomiting and diarrhea, fever, lethargy, and weakness. in severe cases it can lead to kidney failure or death. while this condition is most common in children, it often has a more complicated presentation in adults. treatment may include dialysis, corticosteroids, transfusions of packed red blood cells and plasmapheresis. hemolytic uremic syndrome should be distinguished from atypical hemolytic uremic syndrome (ahus). the two conditions have different causes and different signs and symptoms. last updated: 1/3/2015

MalaCards based summary: Hemolytic-Uremic Syndrome, also known as hemolytic uremic syndrome, is related to hemolytic uremic syndrome, atypical 5 and hemolytic uremic syndrome, atypical 3. An important gene associated with Hemolytic-Uremic Syndrome is CFH (Complement Factor H), and among its related pathways are Formation of Fibrin Clot (Clotting Cascade) and Staphylococcus aureus infection. Affiliated tissues include kidney, endothelial and heart, and related mouse phenotypes are normal and hematopoietic system.

Wikipedia:⁶⁸ Hemolytic-uremic syndrome (or haemolytic-uraemic syndrome), abbreviated HUS, is a disease characterized... more...

Related Diseases for Hemolytic-Uremic Syndrome

Sources:
²⁰GeneCards, ¹⁹GeneAnalytics, ⁶⁵UMLS
See all MalaCards sources

Diseases in the Hemolytic-Uremic Syndrome family:

D-Plus Hemolytic Uremic Syndrome

Diseases related to Hemolytic-Uremic Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 188)

id	Related Disease	Score	Top Affiliating Genes
1	hemolytic uremic syndrome, atypical 5	34.7	C3, CD46
2	hemolytic uremic syndrome, atypical 3	34.6	C3, CFI
3	hemolytic uremic syndrome, atypical 1	33.9	CFH, CFHR1, CFHR3, THBD
4	systemic lupus erythematosus	28.9	ADAMTS13, C3, F3, THBD
5	malaria	28.3	ADAMTS13, F3, THBD, VWF
6	hemolytic uremic syndrome, atypical 4	12.4
7	hemolytic uremic syndrome, atypical 6	12.4
8	hemolytic uremic syndrome, atypical 2	12.4
9	typical hemolytic-uremic syndrome	12.4
10	hemolytic uremic syndrome, atypical, childhood	12.3
11	d-minus hemolytic uremic syndrome	12.2
12	d-plus hemolytic uremic syndrome	12.2
13	thbd-related atypical hemolytic-uremic syndrome	12.2
14	atypical hemolytic-uremic syndrome with thrombomodulin anomaly	12.2
15	atypical hemolytic-uremic syndrome with dgke deficiency	12.2
16	atypical hemolytic-uremic syndrome with b factor anomaly	12.2
17	atypical hemolytic-uremic syndrome with h factor anomaly	12.2
18	atypical hemolytic-uremic syndrome with c3 anomaly	12.2
19	atypical hemolytic-uremic syndrome with mcp/cd46 anomaly	12.2
20	atypical hemolytic-uremic syndrome with i factor anomaly	12.2
21	atypical hemolytic-uremic syndrome with anti-factor h antibodies	12.2
22	c3-related atypical hemolytic-uremic syndrome	12.1
23	cd46-related atypical hemolytic-uremic syndrome	12.1
24	cfb-related atypical hemolytic-uremic syndrome	12.1
25	cfh-related atypical hemolytic-uremic syndrome	12.1
26	cfhr1 and cfhr4-related atypical hemolytic-uremic syndrome	12.1
27	cfhr3 and cfhr1-related atypical hemolytic-uremic syndrome	12.1
28	cfi-related atypical hemolytic-uremic syndrome	12.1
29	dgke-related atypical hemolytic-uremic syndrome	12.1
30	nephrotic syndrome, type 7	11.7
31	complement factor h deficiency	10.9
32	purpura	10.8
33	thrombotic thrombocytopenic purpura	10.8
34	macrocephaly-spastic paraplegia-dysmorphism syndrome	10.8	CFH, CFI
35	brain malformation-congenital heart disease-postaxial polydactyly syndrome	10.8	CFH, CFI
36	multifocal lymphangioendotheliomatosis with thrombocytopenia	10.7	CFB, CFH
37	alternating exotropia	10.7	CFB, CFH
38	pseudoglandular variant testicular seminoma	10.7	C3, CFI
39	hereditary thrombocytosis with transverse limb defect	10.7	CFH, DGKE
40	diarrhea	10.6
41	diabetes mellitus, 6q24-related transient neonatal	10.6	CFH, CFHR5
42	neonatal adrenoleukodystrophy	10.6	C3, CD46
43	pneumonia	10.6
44	focal embolic glomerulonephritis	10.5	C3, CFH
45	endotheliitis	10.5
46	c5 deficiency	10.5	ADAMTS13, CFH
47	glomerulonephritis	10.4
48	stomatocytosis i	10.4	C3, C5
49	follicular dendritic cell sarcoma	10.4	C3, C5
50	pancreatitis	10.4

Comorbidity relations with Hemolytic-Uremic Syndrome via Phenotypic Disease Network (PDN):

Deficiency Anemia	Acute Kidney Failure
Chronic Kidney Failure	Heart Disease

Graphical network of the top 20 diseases related to Hemolytic-Uremic Syndrome:

Symptoms for Hemolytic-Uremic Syndrome

Drugs & Therapeutics for Hemolytic-Uremic Syndrome

Sources:
⁴⁴NIH Clinical Center, ⁴ClinicalTrials, ⁶Cochrane Library, ⁶⁵UMLS, ⁴³NDF-RT, ¹³DrugBank, ²⁶HMDB, ⁹DGIdb, ⁵³PharmGKB, ³⁰IUPHAR, ⁴⁷Novoseek, ¹BitterDB
See all MalaCards sources

Drugs for Hemolytic-Uremic Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 17)

id

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Complement System Proteins

Phase 2, Phase 3

190

2

Immunoglobulins

Phase 3, Phase 2

4477

3

Pharmaceutical Solutions

Phase 3

7004

4

Antibodies

Phase 3, Phase 2

4477

5

Shiga Toxins

Phase 2, Phase 3

4

6

Acetaminophen

approved

Phase 2

864

103-90-2

1983

Synonyms:

4'-Hydroxyacetanilide

4'-hydroxyacetanilide

4-(Acetylamino)phenol

4-Acetamidophenol

4-Acetaminophenol

4-Hydroxyacetanilide

4-Hydroxyanilid kyseliny octove

4-acetamidophenol

7 Select Acetaminophen

7 Select Childrens Pain Relief

8 Hour Pain Relief

A-Per

A.F. Anacin

AC1Q1KYJ

AC1Q1KYK

APAP

Abenol

Abensanil

Abrol

Abrolet

Acamol

Accu-Tap

Acenol

Acephen

Acertol

Aceta Elixir

Aceta Tablets

Acetaco

Acetagesic

Acetalgin

Acetaminofen

Acetaminophen

Acetaminophen (red)

Acetaminophen - Apap 8 Hour

Acetaminophen - Apap Arthritis

Acetaminophen 8 Hour

Acetaminophen 8 hour

Acetaminophen EXTRA STRENGTH

Acetaminophen Easy Tabs Extra Strength

Acetaminophen Extended Release

Acetaminophen Extra Strength

Acetaminophen Junior

Acetaminophen Maximum Strength

Acetaminophen PAIN RELIEF

Acetaminophen Rapid Release

Acetaminophen Rapid Release Extra Strength

Acetaminophen Regular Strength

Acetaminophen Uniserts

Acetaminophen arthritis pain

Acetaminophen easy tabs

Acetaminophen extra strength

Acetaminophen for children

Acetaminophen infants

Acetaminophen pain reliever fever reducer

Acetaminophen pain reliever/fever reducer

Acetaminophen-apap 8 Hour

Acetaminophene

Acetamol

Acetavance

Acetofen

Actamin

Actamin Extra

Actamin Super

Actifed Plus

Actimol

Actimol Chewable Tablets

Actimol Children'S Suspension

Actimol Infants' Suspension

Actimol Junior Strength Caplets

Actron

Afebrin

Afebryl

Aferadol

Algesidal

Algina

Algomol

Algotropyl

Allay

Alpiny

Alpinyl

Alvedon

Amadil

Aminofen

Aminofen Max

Anacin

Anacin 3

Anacin Aspirin Free

Anacin-3

Anacin-3 Extra Strength

Anadin dla dzieci

Anaflon

Analter

Anapap

Andox

Anelix

Anexsia

Anexsia 10/660

Anexsia 5/325

Anexsia 7.5/325

Anexsia 7.5/650

Anhiba

Anoquan

Anti-Algos

Antidol

Anuphen

Apacet

Apacet Capsules

Apacet Elixir

Apacet Extra Strength Caplets

Apacet Extra Strength Tablets

Apacet Regular Strength Tablets

Apadon

Apamid

Apamide

Apap

Apap Extra Strength

Apap extra strength

Aphen

Apinophen EXTRA STRENGTH

Apitrelal

Apo-Acetaminophen

Arfen

Arthralgen

Arthritis 8 Hour

Arthritis Pain

Arthritis Pain Relief

Arthritis Pain Relief temporary minor

Arthritis Pain Reliever

Asetam

Asomal

Aspac

Aspirin Free

Aspirin Free Anacin Maximum Strength Caplets

Aspirin Free Anacin Maximum Strength Gel Caplets

Aspirin Free Anacin Maximum Strength Tablets

Aspirin Free Pain Relief

Aspirin-Free Anacin

Aspirin-Free Excedrin Caplets

Asplin

Atasol

Atasol Caplets

Atasol Drops

Atasol Forte Caplets

Atasol Forte Tablets

Atasol Oral Solution

Atasol Tablets

Atralidon

Aypanal

Babies R Us Childrens Pain Relief

Babies R Us Infants Pain Relief

Babies R Us Pain Relief

Babikan

Bacetamol

Bancap

Bancap Hc

Banesin

Bayer Select

Bayer Select Allergy-Sinus

Bayer Select Head Cold

Bayer Select Headache Pain

Bayer Select Maximum Strength Headache Pain Relief Formula

Bayer Select Menstrual Multi-Symptom

Bayer Select Sinus Pain Relief

Ben-u-ron

Benmyo

Bf-paradac

Bickie-mol

Biocetamol

Bucet

Butalbital

Butapap

CCRIS 3

CHEBI:46195

Cadafen

Calapol

Calmanticold

Calonal

Calpol

Capital

Capital with Codeine

Captin

Care One Arthritis Pain Relief

Care One Arthritis Pain Relief temporary minor

Care One Pain Relief

Care One Pain Relief 8 hour

Care One Pain Relief Childrens

Care One Pain Relief childrens

Care One Pain Relief extra strength

Care One Pain Relief infants

Careone Infants Pain Relief

Careone Pain Relief

Careone Pain Relief infants

Causalon

Cefalex

Cetadol

Cetafen

Cetafen Extra

Children Acetaminophen Grape Flavored Chewable

Children'S Acetaminophen Elixir Drops

Children'S Acetaminophen Oral Solution

Children'S Tylenol Chewable

Children's Pain Relief

Childrens Accudial Pain reliever/ Fever reducer

Childrens Acetaminophen

Childrens Acetaminophen Melts

Childrens Acetaminophen Oral Suspension Grape Flavor

Childrens Aspirin Free Rapid Tabs

Childrens Chewable Acetaminophen

Childrens Chewable Mapap

Childrens Chewable Pain Reliever

Childrens Fever Reducer

Childrens Mapap

Childrens Mapap Acetaminophen

Childrens Non Aspirin

Childrens Nortemp

Childrens Pain Relief

Childrens Pain Relief Acetaminophen

Childrens Pain Relief Bubblegum

Childrens Pain Relief Grape Flavor

Childrens Pain Relief ReadyInCase

Childrens Pain Reliever

Childrens Qpap

Childrens Silapap

Childrens Tylenol

Childrens non aspirin

Circle K Pain Reliever

Claradol Codeine

Clixodyne

Co-Gesic

Cod-Acamol Forte

Codabrol

Codalgin

Codapane

Codicet

Codisal

Codisal Forte

Codoliprane

Codral Pain Relief

Cofamol

Conacetol

Concentrated Aspirin Free infants

Conrx Extra Strength

Contac Cough & Sore Throat Formula

Contra-Schmerz P

Coricidin

Coricidin D

Coricidin Sinus

Cosutone

Counteract Childrens Pain Reliever

Counteract Pain

Croix Blanche

Cuponol

Curadon

Curpol

Custodial

D oliprane

Dafalgan

Dapa

Dapa X-S

Darocet

Darvocet

Darvocet-N 50

Datril

Datril Extra-Strength

Daygrip

Demilets

Deminofen

Democyl

Demogripal

Desfebre

Dg Health Arthritis Pain Relief

Dg Health Childrens Pain Relief

Dg Health Pain Relief

Dg Health Pain Relief Infants

Dg Health Pain Relief childrens

Dg Health Pain Reliever

Dg Health Pain Reliever extra strength

Dhamol

Dhc Plus

Dial-a-gesic

Dial-alpha-gesic

Dimindol

Direct Safety Aspirin Free

Direct Safety Extra Strength Aspirin Free

Dirox

Disprol

Dol-Stop

Dolcor

Dolefin

Dolegrippin

Dolene AP-65

Dolene Ap-65

Dolgesic

Doliprane

Dolko

Dolofin Infantil

Dolofugin

Doloreduct

Dolorfug

Dolorol Forte

Dolorstop

Dolotec

Dolprone

Dorocoff

Dover Aminophen

Dresan

Dristan Cold No Drowsiness

Dristancito

Drixoral Plus

Duaneo

Dularin

Duorol

Duracetamol

Duradyne Dhc

Durapan

Dye-free Childrens Acetaminophen Grape

Dymadon

Dymadon Co

Dymadon Forte

Dypap

Ecosetol

Ed Apap

Elixodyne

Empracet

Endecon

Enelfa

Eneril

Equaline Acetaminophen infants

Equaline Arthritis

Equaline Childrens Acetaminophen

Equaline Infants Acetaminophen

Equaline Pain Relief

Equaline Pain Relief childrens

Equaline Pain Relief concentrated

Equaline Pain Relief extra strength

Equaline Pain Relief infants

Equaline Pain Relief infants concentrated

Equate Acetaminophen

Equate Arthritis Pain

Equate Childrens Acetaminophen

Equate Pain Reliever Extra Strength

Esgic

Esgic-Plus

Eu-Med

Excedrin

Excedrin Caplets

Excedrin Extra Strength Caplets

Excipain

Exdol

Exdol Strong

Extra Strength Acetaminohpen Adult Rapid Burst Cherry

Extra Strength Acetaminophen

Extra Strength Aspirin Free Pain Relief

Extra Strength Headache Relief

Extra Strength Mapap

Extra Strength Non-aspirin

Extra Strength Non-aspirin Pain Reliever

Extra Strength Pain Relief

Extra Strength Pain Relief Acetaminophen

Extra Strength Pain Reliever

Extra Strength Qpap

Extra Strength Wal-nadol

Family Wellness Acetaminophen

Fanalgic

Farmadol

Febranine

Febrectal

Febrectol

Febrex

Febricet

Febridol

Febrilix

Febrin

Febrinol

Febro-Gesic

Febrolin

Femcet

Fendon

Fensum

Fepanil

Fever All

Fever Reducing childrens

Feverall

Feverall Adults

Feverall Children

Feverall Childrens

Feverall Infants

Feverall Jr. Strength

Feverall Junior

Feverall Junior Strength

Feverall Sprinkle Caps Junior Strength

Fevor

Finimal

Finiweh

Fioricet

Fluparmol

Formu Care Pain Relief

Fortalidon P

Fortolin

Freka-cetamol

Fulton Street Market Pain Relief extra strength

Gattaphen T

Gelocatil

Geluprane

Genapap

Genapap Children'S Elixir

Genapap Children'S Tablets

Genapap Extra Strength Caplets

Genapap Extra Strength Tablets

Genapap Regular Strength Tablets

Genebs

Genebs Extra Strength Caplets

Genebs Regular Strength Tablets

Genebs X-Tra

Geralgine-P

Gesteira

Good Neighbor Pharmacy 8 Hour Pain Relief

Good Neighbor Pharmacy Childrens Pain Relief

Good Neighbor Pharmacy Pain Relief

Good Neighbor Pharmacy Pain Relief Infants

Good Neighbor Pharmacy Pain Relief Rapid Release Extra Strength

Good Neighbor Pharmacy Pain Relief childrens

Good Neighbor Pharmacy Pain Relief extra strength

Good Neighbor Pharmacy Pain Relief infants

Good Neighbor Pharmacy Pain Relief regular strength

Good Sense Pain Relief

Good Sense Pain Relief 8 hour

Good Sense Pain Relief Extra Strength

Good Sense Pain Relief arthritis pain

Good Sense Pain Relief childrens

Good Sense Pain Relief extra strength

Good Sense Pain Relief infants concentrated

Good Sense Pain Reliefchildrens childrens

Green Guard Maximum Non-aspirin

Gripin Bebe

Grippostad

Gynospasmine

Health Mart Junior Rapid Melts

Health Mart Pain Relief

Health Sense Tactinal Extra Strength

Health Sense Tactinal Regular Strength

Healthy Accents Arthritis Pain Relief

Healthy Accents Pain Relief

Healthy Accents Pain Relief childrens

Healthy Accents Pain Relief extra strength

Healthy Accents Pain Relief infants

Healthy Mama SHAKE THAT ACHE

Hedex

Helon N

Help I Have A Headache

Henry Schein Acetaminophen

Homoolan

Hy-Phen

Hycomine Compound

Hydrocet

Ildamol

Inalgex

Infadrops

Infants Acetaminophen

Infants Acetaminophen Concentrated

Infants Mapap

Infants Mapap Pain Reliever /Fever Reducer

Infants Pain Relief

Infants Pain Relief Concentrated

Infants Pain Relief concentrated

Infants Pain Reliever

Infants Silapap

Infants Tylenol

Infants concentrated aspirin free

Infants' Feverall

Influbene N

Injectapap

Intensin

Janupap

Jin Gang

Junior Acetaminophen

Junior Aspirin Free Rapid Tabs

Junior Disprol

Junior Pain Relief

Junior Rapid Melts Grape

Junior Strength Acetaminophen

Junior Strength Pain Relief

Junior Strength Pain Reliever

Junior Strength Pain Reliever Grape

KBio1_000660

Kataprin

Kinder Finimal

Kirkland Signature Acetaminophen adult extra strength

Kirkland Signature Arthritis Pain

Kirkland Signature Infants Pain Relief

Kirkland Signature Non Aspirin Extra Strength

Kirkland Signature Pain Relief

Korum

Kratofin simplex

L024125

Labamol

Leader 8 Hour Pain Reliever

Leader Arthritis Pain

Leader Arthritis Pain Reliever

Leader Childrens Pain Reliever

Leader Extra Strength Pain Relief

Leader Pain Relief 8 HR

Leader Pain Relief childrens

Leader Pain Reliever

Leader Pain Reliever childrens

Leader Pain Reliever extra strength

Leader Pain Reliever infants

Leader Pain Reliever infants concentrated

Lekadol

Lemgrip

Lemsip

Lestemp

Lil Drug Store Pain Reliever Extra Strength

Liqiprine

Liquagesic

Liquigesic Co

Liquiprin

Liquiprin Children'S Elixir

Liquiprin Infants" Drops

Little Fevers By Little Remedies

Little Fevers Childrens Fever Pain Reliever

Little Fevers Infant Berry Fever/pain Reliever

Little Fevers Infant Grape Fever/pain Reliever

Lonarid

Lonarid Mono

Lorcet-Hd

Lortab

Lupocet

Lyteca

Lyteca Syrup

Magnidol

Malex N

Malgis

Malidens

Mapap

Mapap Arthritis Pain

Mapap Extra Strength

Mapap childrens

Mapap infants concentrated

Maxadol

Medi First Plus Non-aspirin

Medi First Plus Non-aspirin Extra Strength

Medi-first Non-aspirin

Medi-first Non-aspirin Extra Strength

Medicine Shoppe Arthritis Pain Reliever

Medigesic Plus

Medinol Paediatric

Medique Apap

Medique Apap Extra Strength

Medline Acetaminophen

Medocodene

Melabon Infantil

Members Mark Acetaminophen

Members Mark Arthritis Pain

Mexalen

Midol Maximum Strength

Midol PM Night Time Formula

Midol Regular Strength

Midol Teen Formula

Migraleve Yellow

Minafen

Minoset

Miralgin

Momentum

Mono Praecimed

Moore Medical Extra Strength Non Aspirin

Moore Medical Non Aspirin

Multin

N-(4-Hydroxyphenyl)acetamide

N-Acetyl-4-aminophenol

N-Acetyl-p-aminophenol

N-acetyl-p-aminophenol

NAPA

NCX 701

NEBS

NSC3991

Naldegesic

Napafen

Napap

Naprinol

Nealgyl

Nebs

Neo-Fepramol

NeoCitran

Neodol

Neodolito

Neopap

Neotrend

Neuridon

New Cortal for Children

NilnOcen

Nina

No-Febril

Nobedon

Nodolex

Non Aspirin Childrens

Non Aspirin Extra Strength

Non-aspirin

Noral

Norcet

Norco

Nortemp

O-Acetaminophenol

Ofirmev

Ohm 8 Hour Pain Reliever/fever Reducer

Oltyl

Oralgan

Oraphen-PD

Ortensan

Oxycet

Oxycocet

Oxycodone 2.5/Apap 500

Oxycodone 5/Apap 500

PCM Paracetamol Lichtenstein

Paceco

Pacemo

Pacemol

Pacet

Pacimol

Paedialgon

Paedol

Pain Relief

Pain Relief 8 Hr

Pain Relief 8 hour

Pain Relief Acetaminophen Extra Strength

Pain Relief Childrens

Pain Relief ES

Pain Relief Extra Strength

Pain Relief Infants

Pain Relief Regular Strength

Pain Relief childrens

Pain Relief concentrated infants

Pain Relief extra strength

Pain Relief infants

Pain Relief regular strength

Pain Reliever

Pain Reliever Extra Strength

Pain Reliever Extra Strength (Leader)

Pain Reliever Fever Reducer childrens

Pain Reliever Infants

Pain Reliever Rapid Release

Pain Reliever childrens

Pain Reliever extra strength

Pain Reliever infants

Painex

Paldesic

Pamol

Panacete

Panadeine

Panadeine Co

Panadiene

Panado-Co

Panado-Co Caplets

Panadol

Panadol Extra Strength

Panadol Junior Strength Caplets

Panadol Maximum Strength Caplets

Panadol Maximum Strength Tablets

Panale ve

Panaleve

Panamax

Panasorb

Panasorbe

Panets

Panex

Panodil

Panofen

Pantalgin

Papa-Deine

Papa-Deine #3

Papa-Deine #4

Para-Suppo

Para-Tabs

Paracemol

Paracenol

Paracet

Paracetamol

Paracetamol AL

Paracetamol Antipanin P

Paracetamol BC

Paracetamol Basics

Paracetamol DC

Paracetamol Dr. Schmidgall

Paracetamol Fecofar

Paracetamol Genericon

Paracetamol Hanseler

Paracetamol Harkley

Paracetamol Heumann

Paracetamol Hexal

Paracetamol Italfarmaco

Paracetamol Nycomed

Paracetamol PB

Paracetamol Raffo

Paracetamol Ratiopharm

Paracetamol Rosch

Paracetamol Saar

Paracetamol SmithKline Beecham

Paracetamol Stada

Paracetamol Winthrop

Paracetamol von ct

Paracetamole

Paracetamolo

Paracetamolum

Paracetanol

Paracetol

Paracin

Paracod

Paracodol

Parador

Paradrops

Parakapton

Parake

Paralen

Paralief

Paralink

Paralyoc

Paramol

Paramolan

Paranox

Parapan

Parasedol

Parasin

Paraspen

Parcetol

Parelan

Parmol

Parogal

Paroma

Pasolind

Pasolind N

Pe-Tam

Pediacare Childrens Fever Reducer Pain Reliever Cherry

Pediacare Childrens Fever Reducer Pain Reliever Dye Free

Pediacare Childrens Fever Reducer Pain Reliever Grape

Pediacare Infant Fever Pain Reliever

Pediacare Infants Fever Reducer Cherry

Pediacare Infants Fever Reducer Dye Free

Pediacare Infants Fever Reducer Grape

Pediacare Single Dose Fever Reducer

Pediapirin

Pediatrix

Pedric

Percocet

Percocet-5

Percocet-Demi

Percogesic with Codeine

Perdolan Mono

Perfalgan

Pharbetol

Pharbetol Regular strength

Phenaphen

Phenaphen Caplets

Phenaphen W/Codeine

Phendon

Phenipirin

Phogoglandin

Phrenilin

Phrenilin Forte

Physicianscare Non Aspirin Extra Strength

Pinex

Piramin

Pirinasol

Plicet

Plus Pharma Pain Reliever,Fever Reducer 325 mg

Pluspharma Extra Strength PAIN RELIEVER,FEVER REDUCER 500 mg

Polmofen

Powerful Pain Medicine

Predimol

Predualito

Preferred Plus Arthritis Pain

Preferred Plus Extra Strength Pain Relief

Premier Value Arthritis 8 Hour

Premier Value Arthritis Pain Reliever

Prestwick_13

Prodol

Prompt

Prontina

Propacet

Propacet 100

Proval #3

Puernol

Pulmofen

Pyregesic-C

Pyrigesic

Pyrinazine

Pyromed

Qpap Infants Drops

Quality Choice Extra Strength Pain Relief

Quiet World

Rapid Comfort Extra Strength Non Aspirin

Rapid Comfort Non Aspirin

Rapid Release Acetaminophen

Redutemp

Regular Strength Pain Relief

Regular Strength Pain Reliever

Regular Strength Qpap

Reliv

Remedol

Rexall Arthritis Pain

Rexall Pain Relief

Rhinex D-Lay Tablets

Ringl

Rivalgyl

Robigesic

Robitussin Night Relief

Rockamol Plus

Rounox

Roxicet

Roxicet 5/500

Roxilox

RubieMol

Rubophen

Rugby Acetaminophen

Rupemol

Rx Act Pain Relief

Rx Act Pain Relief 8 Hr

Rx Act Pain Relief Extra Strength

Rx Act Pain Relief Rapid Release

Rx Act Pain Relief extra strength

Rx Act Pain Relief infants

Rx Act Pain Relief regular strength

SK-Apap

SPBio_002836

Salzone

Sanicet

Sanicopyrine

Scanol

Scentalgyl

Scherzatabletten Rezeptur 534

Schmerzex

Sedalito

Sedapap

Semolacin

Servigesic

Seskamol

Setakop

Setamol

Setol

Severe Sinus Congestion

Shoprite Acetaminophen

Shoprite Arthritis Pain

Shoprite Childrens Acetaminophen

Shoprite Infants Acetaminophen

Shoprite Pain Relief

Sifenol

Simply Right Acetaminophen

Simply Right Arthritis Pain

Sinaspril

Sine-Off Sinus Medicine Caplets

Sinedol

Sinmol

Sinubid

Smart Sense Arthritis Pain Relief

Smart Sense Childrens Pain Relief

Smart Sense Infants Pain Relief

Smart Sense Pain Relief

Smart Sense Pain Relief 8 hour

Smart Sense Pain Relief Extra Strength

Smart Sense Pain Relief childrens

Smart Sense Pain Relief extra strength

Smart Sense Pain Relief infants

Snaplets-FR

Sohmed Extra Strength

Spalt N

Spalt fur die nacht

St Joseph Aspirin-Free

St Joseph Aspirin-Free for Children

St. Joseph Cold Tablets for Children

St. Joseph Fever Reducer

Stanback

Stopain

Sudafed Severe Cold Formula

Sudafed Sinus

Sunetheton

Sunmark 8 Hour Pain Relief

Sunmark Arthritis 8 Hour

Sunmark Arthritis Pain Relief

Sunmark Arthritis Pain Reliever

Sunmark Junior Rapid Melts

Sunmark Pain Relief Extra Strength

Sunmark Pain Reliever

Sunmark Pain Reliever Infants

Sunmark Pain Reliever extra strength

Sunmark Pain Reliever infants

Supac

Supadol mono

Supofen

Suppap

Suppap-120

Suppap-325

Suppap-650

Supramol-M

Swift Aypanal Extra

Synalgos-Dc-A

TYL

Tabalgin

Tachiprina

Talacen

Tapanol

Tapanol Extra Strength Caplets

Tapanol Extra Strength Tablets

Tapar

Tavist Allergy/Sinus/Headache

Tazamol

Temlo

Tempanal

Tempra

Tempra Caplets

Tempra Chewable Tablets

Tempra D.S

Tempra Drops

Tempra Syrup

Tencon

Termacet

Termalgin

Termalgine

Termofren

TheraFlu

Tibinide

Tibizide

Tiffy

Tisin

Tisiodrazida

Titralgan

Tizide

Tocris-1706

Topcare 8 Hour Pain Relief

Topcare Arthritis Pain

Topcare Arthritis Pain Relief

Topcare Arthritis Pain Relief Temporary Minor

Topcare Childrens Pain Relief

Topcare Fever Reducer

Topcare Infants Pain Relief

Topcare Pain Relief

Topcare Pain Relief Extra Strength

Topcare Pain Relief Infants

Topcare Pain Relief Rapid Release

Topcare Pain Relief extra strength

Topcare Pain Relief extra strength easy to swallow

Topco Arthritis 8 Hour

Toximer P

Tralgon

Treupel N

Treupel mon

Treuphadol

Triad

Triaminic Fever Reducer

Triaminic Infants Fever Reducer Pain Reliever - Bubblegum

Triaminic Infants Fever Reducer Pain Reliever - Grape

Triaminic Sore Throat Formula

Triaprin

Tricoton

Tussapap

Ty lenol

Tycolet

Tylenol

Tylenol (TN)

Tylenol Allergy Sinus

Tylenol Arthritis Extended Relief

Tylenol Arthritis Pain

Tylenol Caplets

Tylenol Children'S Chewable Tablets

Tylenol Children'S Elixir

Tylenol Children'S Suspension Liquid

Tylenol Cold Sore Throat Extra Strength

Tylenol Drops

Tylenol Elixir

Tylenol Extra Strength

Tylenol Extra Strength Adult Liquid Pain Reliever

Tylenol Extra Strength Caplets

Tylenol Extra Strength Gelcaps

Tylenol Extra Strength Tablets

Tylenol Gelcaps

Tylenol Infants Drops

Tylenol Infants" Suspension Drops

Tylenol Junior Strength Caplets

Tylenol Junior Strength Chewable Tablets

Tylenol Regular Strength

Tylenol Regular Strength Caplets

Tylenol Regular Strength Tablets

Tylenol SORE THROAT

Tylenol Tablets

Tylex

Tylex CD

Tylo Extra Strength

Tylol

Tylox

Tylox-325

Tymol

Ultracet

Upsanol

Utragin

Valadol

Valgesic

Valorin

Valorin Extra

Vanquish

Veralgina

Vermidon

Verpol

Viclor Richet

Vicodin

Vicodin Es

Vicodin Hp

Vips

Viruflu

Vivimed

Volpan

Welby Health Acetaminophen

Wygesic

Xl-dol

Zatinol

Zee Unaspirin ES

Zolben

alpha-Per

p-(Acetylamino)phenol

p-Acetamidophenol

p-Acetaminophenol

p-Acetylaminophenol

p-Hydroxyacetanilide

p-Hydroxyphenolacetamide

p-acetamidophenol

p-acetaminophenol

p-hydroxyacetanilide

p-hydroxyphenolacetamide

7

Diphenhydramine

approved

Phase 2

212

58-73-1, 147-24-0

3100

Synonyms:

147-24-0

147-24-0 (HYDROCHLORIDE)

2-(Benzhydryloxy)-N,N-dimethylethylamine

2-(Benzhydryloxy)-N,N-dimethylethylamine, hydrochloride

2-(Diphenylmethoxy)-N,N-dimethylethylamine

2-(diphenylmethoxy)-N,N-dimethylethanamine

2-Diphenylmethoxy-N,N-dimethylethylamine

2-[(diphenylmethyl)oxy]-N,N-dimethylethanamine

2-benzhydryloxy-N,N-dimethylethanamine

2-benzhydryloxyethyl-N,N-dimethylammonium

2-diphenylmethoxy-N,N-demthylethanamine

2PM

58-73-1

88637-37-0 (citrate (1:1))

AB00053460

AC-13704

AC1L1F65

AKOS003658554

Aleryl

Alledryl

Aller-Med

Allerdryl

Allergan

Allergan B

Allergeval

Allergical

Allergina

Allergival

Allergy

Allergy Relief

Allermax Caplets

Allernix

Amidryl

Antistominum

Antitussive

Antomin

Automin

BENADRYL HCl

BIDD:GT0152

BPBio1_000275

BRD-K47278471-003-05-7

BRN 1914136

BSPBio_000249

BSPBio_002219

Bagodryl

Banophen

Banophen Caplets

Baramine

Beldin

Belix

Ben-allergin

Bena

Benachlor

Benadrin

Benadryl

Benadryl (hydrochloride)

Benadryl Allergy

Benapon

Bendylate

Benhydramin

Benodin

Benodine

Benylan

Benylin

Benzantin

Benzantine

Benzhydramine

Benzhydraminum

Benzhydril

Benzhydroamina

Benzhydryl

Betramin

CAS-147-24-0

CCRIS 1959

CHEBI:127629

CHEBI:4636

CHEMBL657

CID3100

CPD-10890

Childrens Allergy Relief

Childrens Wal-dryl Allergy

Compoz

D00300

DB01075

DB06975

DIPHENHYDRAMINE, ANTISTOMINUM, BENZHYDRAMINE

Dabylen

Debendrin

Dermistina

Dermodrin

Desentol

Diabenyl

Diabylen

Dibendrin

Dibenil

Dibondrin

Difedryl

Difenhidramina

Difenhidramina [INN-Spanish]

Difenhydramin

Difenhydramine

Difenidramina

Difenidramina [Italian]

Dihidral

Dimedrol

Dimedrol base

Dimedrolum

Dimedryl

Dimehydrinate

Dimethylamine benzhydryl ester

Diphamine

Diphantine

Diphen

Diphen Cough

Diphenhist

Diphenhist Captabs

Diphenhydramine

Diphenhydramine (JP15/INN)

Diphenhydramine Base

Diphenhydramine HCl

Diphenhydramine Hydrochloride

Diphenhydramine Salicylate

Diphenhydramine [INN:BAN:JAN]

Diphenhydraminum

Diphenhydraminum [INN-Latin]

Diphenylhydramin

Diphenylhydramine

DivK1c_000368

Dobacen

Dormarex 2

Dryistan

Drylistan

Dylamon

EINECS 200-396-7

Etanautine

FAR 90X2

Genahist

HMS2089E06

HSDB 3066

Help I Cant Sleep

Histaprin

Histaxin

Hyadrine

Hydramine

Hyrexin

I14-6749

IDI1_000368

Ibiodral

Insomnal

KBio1_000368

KBio2_001460

KBio2_004028

KBio2_006596

KBio3_001439

KBioGR_001099

KBioSS_001460

L000227

LS-68208

Lopac-D-3630

Lopac0_000377

MLS002222276

Medidryl

Mephadryl

MolPort-001-783-508

N,N-Dimethyl-2-(diphenylmethoxy)-ethylamine hydrochloride

N-(2-(Diphenylmethoxy)ethyl)-N,N-dimethylamine

N-(Benzhydryloksy-etylo)dwumetyloamina

N-(Benzhydryloksy-etylo)dwumetyloamina [Polish]

N-[2-(BENZHYDRYLOXY)ETHYL]-N,N-DIMETHYLAMINE

NCGC00015335-01

NCGC00015335-02

NCGC00015335-03

NCGC00015335-10

NCGC00024414-03

NCGC00024414-04

NCI60_002916

NCI60_022782

NINDS_000368

NSC665800

Nausen

Nervine Nighttime Sleep-Aid

Nightime Sleep Aid

North Antihistamine

Novamina

Nytol QuickCaps

Nytol Quickcaps

Nytol Quickgels

O-Benzhydryldimethylaminoethanol

O-benzhydryldimethylaminoethanol

Oprea1_254625

PM 255

Prestwick0_000065

Prestwick1_000065

Prestwick2_000065

Prestwick3_000065

Probedryl

Restamin

Restamin (TN)

Rigidil

S51

SMR001307259

SPBio_000961

SPBio_002170

STK103720

STOCK2S-94461

Siladryl

Silphen

Sleep-Eze D

Sleep-Eze D Extra Strength

Spectrum2_000961

Spectrum3_000400

Spectrum4_000520

Spectrum5_000915

Spectrum_000980

Syntedril

Syntodril

TL8003758

Twilite Caplets

UNII-8GTS82S83M

Unisom

Unisom Sleepgels Maximum Strength

Zzzquil

Zzzsleep

alpha-(2-Dimethylaminoethoxy)diphenylmethane

beta-Dimethylamino-aethyl-benzhydryl-aether

beta-Dimethylamino-aethyl-benzhydryl-aether [German]

beta-Dimethylaminoethanol diphenylmethyl ether

beta-Dimethylaminoethyl benzhydryl ether

beta-Dimethylaminoethylbenzhydrylether

beta-dimethylaminoethyl benzhydryl ether

diphenhydramine

nchembio747-comp18

β-dimethylaminoethyl benzhydryl ether

8

Promethazine

approved

Phase 2

212

60-87-7

4927

Synonyms:

(2-Dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine

(2-dimethylamino-2-methyl)ethyl-N-dibenzoparathiazine

(Dimethylamino-2-propyl-10-phenothiazine hydrochloride

10-(2-(Dimethylamino)-2-methylethyl)phenothiazine

10-(2-(Dimethylamino)propyl)phenothiazine

10-(2-Dimethylaminopropyl)phenothiazine

10-[2-(Dimethylamino)propyl]phenothiazine

10-[2-(dimethylamino)Propyl]phenothiazine

10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl- (9CI)

10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, radical ion(1+)

3277 RP

3389 R.p.

38878-40-9

4-27-00-01253 (Beilstein Handbook Reference)

4182 R.p.

60-87-7

73745-50-3

A-91033

AB00053535

AC-15939

AC1L1J92

Antiallersin

Aprobit

Avomine

BPBio1_000744

BRN 0088554

BSPBio_000676

BSPBio_002777

C07404

CCRIS 7056

CHEBI:8461

CHEMBL643

CID4927

Camergan

D00494

DB01069

Dimapp

Dimethylamino-isopropyl-phenthiazin

Dimethylamino-isopropyl-phenthiazin [German]

Diphergan

Diprazin

Diprazine

Diprozin

DivK1c_000005

EINECS 200-489-2

Fargan

Fenazil

Fenetazina

Fenetazine

Genphen

HMS2089E08

HSDB 3173

Hiberna

Histargan

IDI1_000005

Iergigan

InChI=1/C17H20N2S/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19/h4-11,13H,12H2,1-3H3

Isophenergan

Isopromethazine

KBio1_000005

KBio2_001348

KBio2_003916

KBio2_006484

KBio3_001997

KBioGR_001697

KBioSS_001348

L000495

LS-264

Lercigan

Lergigan

Lilly 01516

Lilly 1516

Lopac0_000899

Metaryl

MolPort-001-783-684

N,N,alpha-Trimethyl-10H-phenothiazine-10-ethanamine

N,N,α-trimethyl-10H-phenothiazine-10-ethanamine

N,N-dimethyl-1-(10H-phenothiazin-10-yl)propan-2-amine

N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine

N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine hydrochloride

N-(2'-Dimethylamino-2'-methyl)ethylphenothiazine

N-(2'-dimethylamino-2'-Methyl)ethylphenothiazine

N-Dimethylamino-2-methylethyl thiodiphenylamine

NCGC00015817-10

NCGC00089735-02

NCGC00089735-03

NCI-C60673

NCI60_001878

NINDS_000005

NSC 30321

NSC30321

Oprea1_758749

PROMETHAZINE (SEE ALSO PROMETHAZINE HYDROCHLORIDE 58-33-3)

Pelpica

Phargan

Phenadoz

Phenargan

Phenergan

Phenerzine

Phenoject-50

Phensedyl

Pilothia

Pilpophen

Pipolphene

Prestwick0_000888

Prestwick1_000888

Prestwick2_000888

Prestwick3_000888

Pro-50

Proazaimine

Proazamine

Procit

Promacot

Promazinamide

Promergan

Promesan

Prometasin

Prometazin

Prometazina

Prometazina [INN-Spanish]

Prometazine

Prometh

Promethacon

Promethaine

Promethazin

Promethazine

Promethazine (JAN/INN)

Promethazine Hydrochloride

Promethazine [INN:BAN]

Promethazine hydrochloride

PromethazineHcl

Promethazinum

Promethazinum [INN-Latin]

Promethegan

Promethiazine

Promezathine

Prorex

Protazine

Prothazin

Prothazine

Provigan

Pyrethia

Pyrethiazine

RP 3277

Remsed

Romergan

Rumergan

SKF 1498

SPBio_000799

SPBio_002895

Sominex

Spectrum2_000840

Spectrum3_001019

Spectrum4_001149

Spectrum5_000977

Spectrum_000868

Tanidil

Thiergan

UNII-FF28EJQ494

Valergine

Vallergine

WLN: T C666 BN ISJ B1Y1&N1&1

WY 509

Zipan-25

promethazine

9

Prednisone

approved

Phase 2

1267

53-03-2

5865

Synonyms:

(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione

(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione

(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione

.delta. E

.delta.(sup1)-Cortisone

.delta.-Cortelan

.delta.-Cortisone

.delta.-Cortone

.delta.-E

.delta.1-Cortisone

.delta.1-Dehydrocortisone

.delta.sone

1,2-Dehydrocortisone

1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione

1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione

1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione

1-Cortisone

1-Dehydrocortisone

17,21-Dihydroxypregna-1,4-diene-3,11,20-trione

17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione

53-03-2

68-59-7

81552_FLUKA

AC-11112

AC1L1LB2

AC1Q29EZ

ACon0_000082

ACon1_000297

AI3-52939

Adasone

Ancortone

Apo-Prednisone

Apo-prednisone

BPBio1_000323

BRD-K85883481-001-04-2

BSPBio_000293

Betapar

Bicortone

Bio-0649

C07370

C21H26O5

CCRIS 2646

CHEBI:8382

CHEMBL635

CID5865

CPD001227202

Cartancyl

Colisone

Cortan

Cortancyl

Cortidelt

Cotone

DB00635

Dacorten

Dacortin

Decortancyl

Decortin

Decortisyl

Dehydrocortisone

Dekortin

Delcortin

Dellacort

Dellacort A

Delta Cortelan

Delta E

Delta E.

Delta-Cortelan

Delta-Dome

Delta-cortelan

Delta-cortisone

Delta-cortone

Delta-dome

Deltacortene

Deltacortisone

Deltacortone

Deltasone

Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone

Deltison

Deltisona

Deltisone

Deltra

Di-Adreson

Diadreson

EINECS 200-160-3

Econosone

Encorton

Encortone

Enkortolon

Enkorton

Fernisone

Fiasone

HMS1568O15

HMS2090J13

HSDB 3168

Hostacortin

In-Sone

Incocortyl

Juvason

Kortancyl

LMST02030180

LS-1325

Liquid Pred

Lisacort

Lodotra

MEGxm0_000443

MLS001061265

MLS001304073

MLS001335907

MLS001335908

MLS002154191

MLS002207083

Me-Korti

Metacortandracin

Meticorten

Meticorten (Veterinary)

Metrevet (Veterinary)

MolPort-001-740-041

NCGC00090766-01

NCGC00090766-02

NCGC00090766-03

NCI-C04897

NCI60_000008

NSC 10023

NSC10023

Nisona

Nizon

Novoprednisone

Nurison

Orasone

Origen Prednisone

P1276

P6254_SIGMA

PRD

Panafcort

Panasol

Paracort

Parmenison

Pehacort

Perrigo Prednisone

Precort

Predeltin

Prednicen-M

Prednicorm

Prednicort

Prednicot

Prednidib

Prednilonga

Prednison

Prednisona

Prednisona [INN-Spanish]

Prednisone

Prednisone Intensol

Prednisone [INN:BAN]

Prednisonum

Prednisonum [INN-Latin]

Prednitone

Prednizon

Prednovister

Presone

Prestwick0_000077

Prestwick1_000077

Prestwick2_000077

Prestwick3_000077

Prestwick_405

Pronison

Pronisone

Rayos

Rectodelt

Retrocortine

S1622_Selleck

SAM002264641

SK-Prednisone

SMR000718760

SMR001227202

SPBio_002214

Servisone

Sone

Sterapred

Supercortil

U 6020

UNII-VB0R961HZT

Ultracorten

Ultracortene

WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ

Winpred

Wojtab

ZINC03875357

Zenadrid

Zenadrid (veterinary)

Zenadrid [veterinary]

delta cortelan

delta(sup 1)-Cortisone

delta(sup 1)-Dehydrocortisone

delta-1-Cortisone

delta-1-Dehydrocortisone

delta-Cortisone

delta-Cortone

10

rituximab

approved

Phase 2

1582

174722-31-7

10201696

Synonyms:

AntiCD20

IDEC-102

IDEC-C2B8

Ig gamma-1 chain C region

MabThera

Mabthera

Rituxan

rituximab

11

Antibodies, Monoclonal

Phase 2

2413

12

Immunologic Factors

Phase 2

18483

13

Antirheumatic Agents

Phase 2

8496

14

Metoclopramide

approved, investigational

102

364-62-5

4168

Synonyms:

(metaclopramide)4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide

(metoclopramide)4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide

1,5-Dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one

2-Methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide

2-Methoxy-4-amino-5-chloro-N,N-dimethylaminoethyl)benzamide

2-Methoxy-5-chloroprocainamide

2-methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide

2-methoxy-5-chloroprocainamide

2576-84-3 (di-hydrochloride)

364-62-5

4 Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide

4-Amino-5-chloro-2-methoxy-N-(beta-diethylaminoethyl)benzamide

4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide

4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamide

4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide

4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide (Mcp)

4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide (metoclopramide)

4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide(Metoclopramide)

4-amino-5-chloro-2-Methoxy-N-(beta-diethylaminoethyl)benzamide

4-amino-5-chloro-N-(2-(Diethylamino)ethyl)-2-methoxybenzamide

4-amino-5-chloro-N-(2-(Diethylamino)ethyl)-O-anisamide

4-amino-5-chloro-N-(2-diethylaminoethyl)-2-methoxybenzamide

4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide

5-Chloro-2-methoxyprocainamide

54143-57-6 (mono-hydrochloride, mono-hydrate)

7232-21-5 (mono-hydrochloride)

AB00053498

AC1L1HKD

AKOS000280832

ARONIS24307

Apo-Metoclop

BPBio1_000217

BPBio1_001100

BRD-K75641298-001-01-5

BRD-K75641298-003-05-2

BRN 1884366

BSPBio_000197

BSPBio_002027

Benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxy- (9CI)

Biomol-NT_000082

C07868

C14H22ClN3O2

CAS-7232-21-5

CHEBI:107736

CHEMBL86

CID4168

CLOPRA-"YELLOW"

Cerucal

Clopra

Clopra-Yellow

Clopromate

D00726

DB01233

DEL

DEL 1267

DivK1c_000069

Duraclamid

EINECS 206-662-9

Elieten

Elieten (TN)

Emetid

Emitasol

Emperal

Eucil

Gastrese

Gastro-Timelets

Gastrobid

Gastromax

Gastronerton

Gastrosil

Gastrotablinen

Gastrotem

HMS2089G16

IDI1_000069

Imperan

KBio1_000069

KBio2_002118

KBio2_004686

KBio2_007254

KBio3_001527

KBioGR_001307

KBioSS_002118

L001078

LS-20038

Lopac-M-0763

Lopac0_000762

Maxeran

Maxolon

Meclopran

Metaclopramide

Metaclopromide

Metamide

Methochlopramide

Methoclopramide

Metochlopramide

Metoclol

Metoclopramida

Metoclopramida [INN-Spanish]

Metoclopramide

Metoclopramide (JP15/INN)

Metoclopramide Hcl

Metoclopramide Hydrochloride

Metoclopramide Intensol

Metoclopramide Monohydrochloride, Monohydrate

Metoclopramide Omega

Metoclopramide [INN:BAN:JAN]

Metoclopramidum

Metoclopramidum [INN-Latin]

Metocobil

Metonia

Metramid

MolPort-000-883-854

Moriperan

Mygdalon

N-(Diethylaminoethyl)-2-methoxy-4-amino-5-chlorobenzamide

NCGC00015643-01

NCGC00015643-02

NCGC00015643-03

NCGC00015643-08

NCGC00024440-03

NCGC00024440-04

NCI60_003185

NINDS_000069

Neu-Sensamide

Nu-Metoclopramide

Octamide

Parmid

Paspertin

Peraprin

Plasil

Plasil (pharmaceutical)

Pms-Metoclopramide

Pramidin

Pramiel

Pramin

Prestwick0_000209

Prestwick1_000209

Prestwick2_000209

Prestwick3_000209

Primperan

Reclomide

Reglan

Reliveran

SPBio_001740

SPBio_002118

ST024773

Spectrum2_001720

Spectrum3_000504

Spectrum4_000964

Spectrum5_001449

Spectrum_001638

Terperan

Terperan (TN)

UNII-L4YEB44I46

bmse000779

metoclopramide

o-Anisamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)- (8CI)

15

dipyrone

39

16

Natriuretic Peptide, Brain

176

17

Immunotoxins

70

Interventional clinical trials:

(show all 31)

id	Name	Status	NCT ID	Phase
1	Study Assessing an Algorithm-based Strategy of Eculizumab Discontinuation in Children and Adults With aHUS	Recruiting	NCT02574403	Phase 4
2	Eval. of Potential Predictors of Disease Progression in Patients With aHUS Including Genetics, Biomarkers and Treatment	Enrolling by invitation	NCT02614898	Phase 4
3	Phase III Randomized Study of SYNSORB Pk in Children With E. Coli-Associated Hemolytic Uremic Syndrome	Completed	NCT00004465	Phase 3
4	Safety and Efficacy Study of Eculizumab in Shiga-Toxin Producing Escherichia Coli Hemolytic-Uremic Syndrome (STEC-HUS)	Completed	NCT01410916	Phase 2, Phase 3
5	Eculizumab in Shiga-toxin Related Hemolytic and Uremic Syndrome Pediatric Patients - ECULISHU	Recruiting	NCT02205541	Phase 3
6	The Plasma Large-Volume Exchange RCT	Withdrawn	NCT01433003	Phase 3
7	An Open-label, Multi-center Clinical Trial of Eculizumab in Adult Patients With Atypical Hemolytic-uremic Syndrome	Completed	NCT01194973	Phase 2
8	An Open-Label, Multi-Center Clinical Trial of Eculizumab in Pediatric Patients With Atypical Hemolytic-Uremic Syndrome	Completed	NCT01193348	Phase 2
9	Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-sensitive Atypical Hemolytic Uremic Syndrome (aHUS)	Completed	NCT00838513	Phase 2
10	Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-Resistant aHUS	Completed	NCT00844545	Phase 2
11	Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Resistant aHUS	Completed	NCT00844844	Phase 2
12	Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Sensitive aHUS	Completed	NCT00844428	Phase 2
13	Study of Chimeric Monoclonal Antibodies to Shiga Toxins 1 and 2	Completed	NCT01252199	Phase 2
14	Complement Inhibition in aHUS Dialysis Patients	Recruiting	NCT02464891	Phase 2
15	Rituximab in Patients With Relapsed or Refractory TTP-HUS	Recruiting	NCT00531089	Phase 2
16	The Safety and Efficacy of Eculizumab in Japanese Patients With Atypical Hemolytic Uremic Syndrome (aHUS)	Recruiting	NCT01757431	Phase 2
17	Safety and Efficacy Study of OMS721 in Patients With Thrombotic Microangiopathies	Recruiting	NCT02222545	Phase 2
18	Safety and Effect of GL-ONC1 Administered IV With or Without Eculizumab Prior to Surgery to Patients With Solid Organ Cancers Undergoing Surgery	Recruiting	NCT02714374	Phase 1
19	Outbreak of Hemolytic Uremic Syndrome Linked to Escherichia Coli of Serotype O104:H4	Completed	NCT01406288
20	Haemolytic Uraemic Syndrome in Childhood: Clinical, Cognitive and Psychological Aspects	Completed	NCT01666548
21	A Retrospective, Observational, Non-interventional Trial to Assess Eculizumab Treatment Effect in Patients With Atypical Hemolytic Uremic Syndrome (aHUS)	Completed	NCT01770951
22	To Characterize the Safety and Tolerability of Eculizumab in Two Japanese aHUS Patients	Completed	NCT01755429
23	The Role of Endothelium Dysfunction in Progression of CKD (Chronic Kidney Disease) After AKI (Acute Kidney Injury)	Completed	NCT00358306
24	Study of Repetitive Intestinal Lavage in Patients With EHEC Associated Hemorrhagic Colitis	Completed	NCT01561248
25	Atypcial Hemolytic-Uremic Syndrome (aHUS) Registry	Recruiting	NCT01522183
26	Complement Activation During Hemodialysis in Atypical Hemolytic Uraemic Syndrome as Underlying Kidney Disease	Recruiting	NCT00930423
27	Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer Treatment	Recruiting	NCT01087333
28	Early Predictive Factors of Cardiac and Cerebral Involvement in TMA	Recruiting	NCT02134171
29	aHUS Observational Long Term Follow-Up	Enrolling by invitation	NCT01522170
30	The Role of Microparticles as a Biomarker	Not yet recruiting	NCT02626663
31	International Registry and Biorepository for TMA(Thrombotic Microangiopathy)	Terminated	NCT00593229

Search NIH Clinical Center for Hemolytic-Uremic Syndrome

Cochrane evidence based reviews: hemolytic-uremic syndrome

Genetic Tests for Hemolytic-Uremic Syndrome

Anatomical Context for Hemolytic-Uremic Syndrome

Sources:
³³MalaCards
See all MalaCards sources

MalaCards organs/tissues related to Hemolytic-Uremic Syndrome:

³³

Kidney, Endothelial, Heart, Lung, Liver, Brain, Breast

Animal Models for Hemolytic-Uremic Syndrome or affiliated genes

Sources:
³⁸MGI
See all MalaCards sources

MGI Mouse Phenotypes related to Hemolytic-Uremic Syndrome:

³⁸

id	Description	MGI Source Accession	Score	Top Affiliating Genes
1	normal	MP:0002873	7.8	ADAMTS13, C3, C5, CFB, CFH, F3
2	hematopoietic system	MP:0005397	7.5	ADAMTS13, C3, CFB, CFH, CFI, F3
3	homeostasis/metabolism	MP:0005376	6.7	ADAMTS13, C3, C5, CFB, CFH, CFI
4	immune system	MP:0005387	6.6	ADAMTS13, C3, C5, CFB, CFH, F3

Publications for Hemolytic-Uremic Syndrome

Sources:
⁵⁴PubMed
See all MalaCards sources

Articles related to Hemolytic-Uremic Syndrome:

(show top 50) (show all 799)

id	Title	Authors	Year
1	No association between dysplasminogenemia with p.Ala620Thr mutation and atypical hemolytic uremic syndrome. (27194432)	Miyata T.... Nangaku M.	2016
2	Indications of underdiagnosis of Atypical Hemolytic Uremic Syndrome in a cohort referred to the Coagulation Unit in Malmo, Sweden, for analysis of ADAMTS13 2007-2012. (27175932)	A8kesson A.... Zetterberg E.	2016
3	Recovery of thalamic microstructural damage after Shiga toxin 2-associated hemolytic-uremic syndrome. (26189050)	KrAomer J.... Meuth S.G.	2015
4	Hemolytic Uremic Syndrome is associated with dysregulation of Chemokine Receptor expression in Circulating Monocytes. (25748554)	Ramos M.V.... Palermo M.S.	2015
5	Role of the skin biopsy in the diagnosis of atypical hemolytic uremic syndrome. (25893747)	Magro C.M.... Laurence J.C.	2015
6	Atypical hemolytic uremic syndrome: the role of complement pathway gene mutation analysis. (25003358)	Weitz I.C.	2014
7	Clinical and epidemiological peculiarities of hemorrhagic colitis complicated by hemolytic-uremic syndrome. (25341242)	Pachkoria E.... Tevzadze L.	2014
8	Natural History of Thrombotic Thrombocytopenic Purpura and Hemolytic Uremic Syndrome. (25377323)	Wada H.... Yamashita Y.	2014
9	Enterohemorrhagic Escherichia coli Infections and the Hemolytic-Uremic Syndrome. (23809720)	Page A.V.... Liles W.C.	2013
10	Hemolytic uremic syndrome related to cryptosporidium infection in an immunocompetent child. (24330289)	Printza N.... Papachristou F.	2013
11	Multifaceted hemolytic uremic syndrome in pediatrics. (23343552)	Nester C.M.	2013
12	Untying the knot of thrombotic thrombocytopenic purpura and atypical hemolytic uremic syndrome. (23410558)	Tsai H.M.	2013
13	Eculizumab in atypical hemolytic-uremic syndrome. (24088108)	Kistler A.D.	2013
14	Factor I autoantibodies in patients with atypical hemolytic uremic syndrome: disease-associated or an epiphenomenon? (22223611)	Kavanagh D.... Marchbank K.J.	2012
15	Interpretation of genetic variants of uncertain significance in atypical hemolytic uremic syndrome. (22170528)	Kavanagh D.... Anderson H.E.	2012
16	Complement factor H variants I890 and L1007 while commonly associated with atypical hemolytic uremic syndrome are polymorphisms with no functional significance. (21881555)	Tortajada A.... de CA^rdoba S.R.	2012
17	Atypical hemolytic uremic syndrome-associated variants and autoantibodies impair binding of factor h and factor h-related protein 1 to pentraxin 3. (22786770)	Kopp A.... JA^zsi M.	2012
18	Hemorrhagic colitis in postdiarrheal hemolytic uremic syndrome: retrospective analysis of 54 children. (21809003)	Rahman R.C.... Gatti M.C.	2012
19	Eculizumab therapy in a child with hemolytic uremic syndrome and CFI mutation. (22903728)	Cayci F.S.... Gur G.	2012
20	Efficacy of eculizumab in a patient with factor-H-associated atypical hemolytic uremic syndrome. (21161283)	Lapeyraque A.L.... Robitaille P.	2011
21	Successful therapeutic plasma exchange in a 3.2-kg body weight neonate with atypical hemolytic uremic syndrome. (21322001)	Jung S.... Chang Y.S.	2011
22	Atypical hemolytic uremic syndrome in the Tunisian population. (20499172)	Leban N.... Haj Khelil A.	2011
23	Acute renal replacement therapy in children with diarrhea-associated hemolytic uremic syndrome: a single center 16 years of experience. (21716936)	Grisaru S.... Hamiwka L.A.	2011
24	Therapeutic plasma exchange in patients with thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: the 10-year experience of a single center. (21418736)	Kim J.W.... Kim B.K.	2011
25	Pregnancy-associated hemolytic uremic syndrome revisited in the era of complement gene mutations. (20203157)	Fakhouri F.... FrAcmeaux-Bacchi V.	2010
26	Shiga toxin-associated hemolytic uremic syndrome: pathophysiology of endothelial dysfunction. (20424866)	Zoja C.... Morigi M.	2010
27	Atypical hemolytic uremic syndrome and mutation analysis of factor H gene in two Tunisian families. (21694933)	Habibi I.... Gorgi Y.	2010
28	Treatment of typical (enteropathic) hemolytic uremic syndrome. (20865636)	Bitzan M.... Reymond D.	2010
29	Atypical hemolytic uremic syndrome associated with mutations in complement regulator genes. (20865641)	Le Quintrec M.... FrAcmeaux-Bacchi V.	2010
30	Triggering of atypical hemolytic uremic syndrome by influenza A (H1N1). (20540647)	Bento D.... Meneses-Oliveira C.	2010
31	An outbreak of diarrhea-associated childhood hemolytic uremic syndrome: the Walkerton epidemic. (19180130)	Matsell D.G.... White C.T.	2009
32	The thrombotic thrombocytopenic purpura and hemolytic uremic syndromes: overview of pathogenesis (Experience of The Oklahoma TTP-HUS Registry, 1989-2007). (19180141)	George J.N.	2009
33	Clostridium septicum myonecrosis complicating diarrhea-associated hemolytic uremic syndrome. (18301926)	Hunley T.E.... Jabs K.	2008
34	Hemolytic uremic syndrome following Hemiscorpius lepturus (scorpion) sting. (20142930)	Valavi E.... Ansari M.J.	2008
35	Mutations in proteins of the alternative pathway of complement and the pathogenesis of atypical hemolytic uremic syndrome. (18423815)	Abarrategui-Garrido C.... SA!nchez-Corral P.	2008
36	Pancreatitis preceding acute episodes of thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: report of five patients with a systematic review of published reports. (17606444)	Swisher K.K.... George J.N.	2007
37	The interactive Factor H-atypical hemolytic uremic syndrome mutation database and website: update and integration of membrane cofactor protein and Factor I mutations with structural models. (17089378)	Saunders R.E.... Perkins S.J.	2007
38	Involvement of the fractalkine pathway in the pathogenesis of childhood hemolytic uremic syndrome. (17132725)	Ramos M.V.... Palermo M.S.	2007
39	The role of defective complement control in hemolytic uremic syndrome. (16575689)	Zipfel P.F.... Skerka C.	2006
40	Role of fibroblast growth factor-binding protein in the pathogenesis of HIV-associated hemolytic uremic syndrome. (16352855)	Ray P.E.... Wellstein A.	2006
41	ADAMTS13, thrombotic thrombocytopenic purpura, and hemolytic uremic syndrome. (15865866)	George J.N.	2005
42	ADAMTS13 activity in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: relation to presenting features and clinical outcomes in a prospective cohort of 142 patients. (12637323)	Vesely S.K.... Raskob G.E.	2003
43	Anticardiolipin antibodies in D+ hemolytic uremic syndrome. (12478355)	e Loo M.... Monnens L.	2002
44	Circulating inflammatory cytokine levels in hemolytic uremic syndrome. (10603133)	Litalien C.... Seidman E.	1999
45	Markers of thrombin generation in kidney failure of children with epidemic hemolytic uremic syndrome]. (9674202)	Marta R.F.... Molinas F.C.	1998
46	Activation of both coagulation and fibrinolysis in childhood hemolytic uremic syndrome. (9767551)	van Geet C.... Declerck P.J.	1998
47	A 12-year-old boy with fatal hemolytic-uremic-syndrome, excessive neutrophilia and elevated endogenous granulocyte-colony-stimulating-factor serum concentrations. (9710348)	Vierzig A.... Michalk D.	1998
48	Profiles of circulating inflammatory- and anti-inflammatory cytokines in patients with hemolytic uremic syndrome due to E. coli O157 infection. (9702419)	Murata A.... Okada S.	1998
49	Enterohemorrhagic Escherichia coli and hemolytic-uremic syndrome]. (9381722)	Allerberger F.... Karch H.	1997
50	Atypical Hemolytic-Uremic Syndrome (20301541)	Pagon R.A.... Stephens K.	1993

Genes related to Hemolytic-Uremic Syndrome

Sources:
²⁰GeneCards, ¹²DISEASES, ⁴⁷Novoseek
See all MalaCards sources

Genes related to Hemolytic-Uremic Syndrome:

(show all 14)

- Elite gene

- Cancer Census gene in COSMIC

id	Symbol	Description	Score	Implication	PubmedIds
1	CFH	Complement Factor H	72.30	DISEASES inferred ¹² Novoseek inferred ⁴⁷ GeneCards inferred via : Disorders, Publications, Summaries, Variants (show sections)	11446651, 17022693, 2024653 more 17526759, 11446657
2	CFI	Complement Factor I	61.25	DISEASES inferred ¹² GeneCards inferred via : Disorders, Publications, Summaries, Variants (show sections)
3	CD46	CD46 Molecule	60.93	DISEASES inferred ¹² GeneCards inferred via : Disorders, Publications, Summaries, Variants (show sections)
4	C3	Complement Component 3	60.74	DISEASES inferred ¹² GeneCards inferred via : Disorders, Publications, Summaries, Variants (show sections)
5	CFB	Complement Factor B	48.52	DISEASES inferred ¹² GeneCards inferred via : Disorders, Publications, Variants (show sections)
6	THBD	Thrombomodulin	48.21	DISEASES inferred ¹² GeneCards inferred via : Disorders, Publications, Variants (show sections)
7	DGKE	Diacylglycerol Kinase Epsilon	47.35	DISEASES inferred ¹² GeneCards inferred via : Disorders, Publications, Variants (show sections)
8	CFHR1	Complement Factor H Related 1	38.52	DISEASES inferred ¹² GeneCards inferred via : Publications, Summaries (show sections)
9	CFHR3	Complement Factor H Related 3	37.41	DISEASES inferred ¹² GeneCards inferred via : Publications, Summaries (show sections)
10	ADAMTS13	ADAM Metallopeptidase With Thrombospondin Type 1 Motif 13	36.94	DISEASES inferred ¹² Novoseek inferred ⁴⁷ GeneCards inferred via : Publications (show sections)	16411392, 14631548, 11992240 more 17627784
11	CFHR5	Complement Factor H Related 5	36.53	DISEASES inferred ¹² GeneCards inferred via : Disorders, Publications (show sections)
12	VWF	Von Willebrand Factor	32.01	DISEASES inferred ¹² Novoseek inferred ⁴⁷ GeneCards inferred via : Publications (show sections)	2191307, 11446662, 14631548
13	C5	Complement Component 5	24.89	DISEASES inferred ¹² GeneCards inferred via : Publications (show sections)
14	F3	Coagulation Factor III, Tissue Factor	24.40	DISEASES inferred ¹² GeneCards inferred via : Publications (show sections)

Variations for Hemolytic-Uremic Syndrome

Expression for genes affiliated with Hemolytic-Uremic Syndrome

Sources:
¹⁷Gene Expression Omnibus DataSets
See all MalaCards sources

Search GEO for disease gene expression data for Hemolytic-Uremic Syndrome.

Pathways for genes affiliated with Hemolytic-Uremic Syndrome

Sources:
⁵²PathCards, ⁵⁷Reactome, ⁵⁶R&D Systems, ³⁹NCBI BioSystems Database, ⁵⁵QIAGEN, ³¹KEGG, ⁶²Thomson Reuters, ⁵⁸SinoBiological
See all MalaCards sources

Pathways related to Hemolytic-Uremic Syndrome according to GeneCards Suite gene sharing:

id	Super pathways	Score	Top Affiliating Genes
1	Formation of Fibrin Clot (Clotting Cascade)⁵⁷ Show member pathways Intrinsic Pathway of Fibrin Clot Formation⁵⁷ Blood Coagulation Signaling Pathways⁵⁶ Blood Clotting Cascade³⁹ Extrinsic Prothrombin Activation Pathway⁵⁵ Common Pathway of Fibrin Clot Formation⁵⁷ Extrinsic Pathway of Fibrin Clot Formation⁵⁷	9.0	F3, THBD, VWF
2	Staphylococcus aureus infection³¹	8.6	C3, C5, CFB, CFH, CFI
3	Immune response Lectin induced complement pathway⁶² Show member pathways Classical Complement Pathway⁵⁵ Immune response Classical complement pathway⁶² Regulation of Complement cascade⁵⁷ Complement Pathway⁵⁵ Lectin Induced Complement Pathway⁵⁵ Complement Activation Pathways⁵⁸ Activation of C3 and C5⁵⁷ Immune response Alternative complement pathway⁶² Terminal pathway of complement⁵⁷ Alternative Complement Pathway⁵⁵	7.9	C3, C5, CD46, CFB, CFH, CFHR3
4	Creation of C4 and C2 activators⁵⁷ Show member pathways Complement cascade⁵⁷ Initial triggering of complement⁵⁷ Classical antibody-mediated complement activation⁵⁷ CD22 mediated BCR regulation⁵⁷ Alternative complement activation⁵⁷ Complement Activation, Classical Pathway³⁹ Ficolins bind to repetitive carbohydrate structures on the target cell surface⁵⁷ Lectin pathway of complement activation⁵⁷ B-Cell Receptor Complex⁵⁵	7.9	C3, C5, CD46, CFB, CFH, CFHR3
5	Immune System⁵⁷ Show member pathways Innate Immune System⁵⁷ Adaptive Immune System⁵⁷	7.3	C3, C5, CD46, CFB, CFH, CFHR3
6	Complement and coagulation cascades³¹ ³⁹ Show member pathways Complement and Coagulation Cascades³⁹	6.8	C3, C5, CD46, CFB, CFH, CFI

GO Terms for genes affiliated with Hemolytic-Uremic Syndrome

Sources:
¹⁸Gene Ontology
See all MalaCards sources

Biological processes related to Hemolytic-Uremic Syndrome according to GeneCards Suite gene sharing:

id	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of vascular endothelial growth factor production	GO:0010575	9.8	C3, C5
2	proteolysis	GO:0006508	9.5	ADAMTS13, C3, CD46
3	regulation of complement activation	GO:0030449	9.3	C3, C5, CD46
4	complement activation, classical pathway	GO:0006958	9.2	C5, CD46, CFI
5	complement activation	GO:0006956	9.0	C3, C5, CFH
6	positive regulation of angiogenesis	GO:0045766	8.5	C3, C5, F3