MCID: HML001
MIFTS: 49

Hemolytic-Uremic Syndrome

Categories: Rare diseases, Immune diseases, Blood diseases, Nephrological diseases

Aliases & Classifications for Hemolytic-Uremic Syndrome

MalaCards integrated aliases for Hemolytic-Uremic Syndrome:

Name: Hemolytic-Uremic Syndrome 12 52 42 14 69
Hemolytic Uremic Syndrome 12 50 29
Acute Renal Failure, Thrombocytopenia, and Microangiopathic Hemolytic Anemia Associated with Distorted Erythrocytes 50
Haemolytic-Uraemic Syndrome 12
Hus 50

Classifications:



External Ids:

Disease Ontology 12 DOID:12554
ICD10 33 D59.3
ICD9CM 35 283.11
MeSH 42 D006463
NCIt 47 C75545
SNOMED-CT 64 111407006 123308008
UMLS 69 C0019061

Summaries for Hemolytic-Uremic Syndrome

NIH Rare Diseases : 50 hemolytic uremic syndrome (hus) is a disorder that usually occurs when an  e. coli bacterial infection in the digestive system produces toxic substances that destroy red blood cells. symptoms include vomiting and diarrhea, fever, lethargy, and weakness. in severe cases it can lead to kidney failure or death. while this condition is most common in children, it often has a more complicated presentation in adults. treatment may include dialysis, corticosteroids, transfusions of packed red blood cells and plasmapheresis.   hemolytic uremic syndrome should be distinguished from atypical hemolytic uremic syndrome (ahus). the two conditions have different causes and different signs and symptoms. last updated: 1/3/2015

MalaCards based summary : Hemolytic-Uremic Syndrome, also known as hemolytic uremic syndrome, is related to hemolytic uremic syndrome, atypical 3 and hemolytic uremic syndrome, atypical 5. An important gene associated with Hemolytic-Uremic Syndrome is CFH (Complement Factor H), and among its related pathways/superpathways are Innate Immune System and Creation of C4 and C2 activators. The drugs Complement System Proteins and Shiga Toxins have been mentioned in the context of this disorder. Affiliated tissues include kidney, endothelial and liver, and related phenotype is renal/urinary system.

Wikipedia : 72 Hemolytic-uremic syndrome (or haemolytic-uraemic syndrome), abbreviated HUS, is a disease characterized... more...

Related Diseases for Hemolytic-Uremic Syndrome

Diseases in the Hemolytic-Uremic Syndrome family:

D-Plus Hemolytic Uremic Syndrome

Diseases related to Hemolytic-Uremic Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 176)
id Related Disease Score Top Affiliating Genes
1 hemolytic uremic syndrome, atypical 3 34.7 C3 CFI
2 hemolytic uremic syndrome, atypical 5 34.7 C3 CD46
3 hemolytic uremic syndrome, atypical 1 32.9 CFH CFHR1 CFHR3 CFHR5 DGKE THBD
4 complement factor h deficiency 32.7 CD46 CFH CFHR1 CFI
5 hemolytic uremic syndrome, atypical 4 12.5
6 hemolytic uremic syndrome, atypical 6 12.5
7 hemolytic uremic syndrome, atypical 2 12.5
8 hemolytic uremic syndrome, atypical, childhood 12.4
9 d-minus hemolytic uremic syndrome 12.1
10 d-plus hemolytic uremic syndrome 12.1
11 atypical hemolytic-uremic syndrome with h factor anomaly 12.1
12 genetic atypical hemolytic-uremic syndrome 12.1
13 thbd-related atypical hemolytic-uremic syndrome 12.1
14 c3-related atypical hemolytic-uremic syndrome 12.0
15 cd46-related atypical hemolytic-uremic syndrome 12.0
16 cfb-related atypical hemolytic-uremic syndrome 12.0
17 cfh-related atypical hemolytic-uremic syndrome 12.0
18 cfhr1 and cfhr4-related atypical hemolytic-uremic syndrome 12.0
19 cfhr3 and cfhr1-related atypical hemolytic-uremic syndrome 12.0
20 cfi-related atypical hemolytic-uremic syndrome 12.0
21 dgke-related atypical hemolytic-uremic syndrome 12.0
22 nephrotic syndrome, type 7 11.9
23 shigellosis 11.5
24 pancreatitis, pediatric 11.1
25 sporadic adult-onset ataxia of unknown etiology 10.8 CFH CFI
26 multiple familial trichoepithelioma 10.7 CFB CFH
27 endosalpingiosis 10.7 CFB CFH
28 purpura 10.7
29 thrombotic thrombocytopenic purpura 10.7
30 symphalangism, proximal, 1a 10.7 CFH DGKE
31 iliac vein thrombophlebitis 10.6 CFB CFH
32 diarrhea 10.6
33 porphyria, acute hepatic 10.5 ADAMTS13 CFH
34 methylmalonic aciduria and homocystinuria, cblc type 10.5 CD46 DGKE
35 rhizomelic chondrodysplasia punctata 10.5 C3 CFB CFH
36 pneumonia 10.5
37 neonatal meningitis 10.5 C3 CD46
38 unna-thost palmoplantar keratoderma 10.4 THBD VWF
39 endotheliitis 10.4
40 diffuse glomerulonephritis 10.4 C3 CFH
41 glomerulonephritis 10.4
42 elizabethkingia anophelis infection 10.3 THBD VWF
43 chronic mucocutaneous candidiasis 10.3 C3 CD40LG
44 facial paralysis 10.3 CD40LG CFB
45 encephalopathy 10.3
46 pancreatitis 10.3
47 temporal arteritis 10.3 CD40LG CD46
48 ube2t-related fanconi anemia 10.3 ADAMTS13 VWF
49 van maldergem syndrome 2 10.2 C3 CFI VWF
50 histiocytic and dendritic cell cancer 10.2 C3 CFB CFH CFI

Comorbidity relations with Hemolytic-Uremic Syndrome via Phenotypic Disease Network (PDN):


Acute Kidney Failure Chronic Kidney Failure
Deficiency Anemia Heart Disease

Graphical network of the top 20 diseases related to Hemolytic-Uremic Syndrome:



Diseases related to Hemolytic-Uremic Syndrome

Symptoms & Phenotypes for Hemolytic-Uremic Syndrome

MGI Mouse Phenotypes related to Hemolytic-Uremic Syndrome:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 renal/urinary system MP:0005367 9.17 C3 C5 CD40LG CFB CFH CFI

Drugs & Therapeutics for Hemolytic-Uremic Syndrome

Drugs for Hemolytic-Uremic Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 19)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Complement System Proteins Phase 2, Phase 3
2 Shiga Toxins Phase 2, Phase 3, Phase 1
3 Antibodies Phase 3,Phase 2
4 Immunoglobulins Phase 3,Phase 2
5 Pharmaceutical Solutions Phase 3,Phase 1
6 Complement Inactivating Agents Phase 3
7
Acetaminophen Approved Phase 2 103-90-2 1983
8
Diphenhydramine Approved Phase 2 58-73-1, 147-24-0 3100
9
Prednisone Approved, Vet_approved Phase 2 53-03-2 5865
10
Promethazine Approved Phase 2 60-87-7 4927
11
rituximab Approved Phase 2 174722-31-7 10201696
12 Antirheumatic Agents Phase 2
13 Antibodies, Monoclonal Phase 2
14
Metoclopramide Approved, Investigational 364-62-5 4168
15 dipyrone
16 Antibodies, Blocking
17 Immunotoxins
18 Natriuretic Agents
19 Natriuretic Peptide, Brain

Interventional clinical trials:

(show all 38)

id Name Status NCT ID Phase Drugs
1 Study Assessing an Algorithm-based Strategy of Eculizumab Discontinuation in Children and Adults With aHUS Recruiting NCT02574403 Phase 4 eculizumab
2 Eval. of Potential Predictors of Disease Progression in Patients With aHUS Including Genetics, Biomarkers and Treatment Enrolling by invitation NCT02614898 Phase 4
3 Safety and Efficacy Study of Eculizumab in Shiga-Toxin Producing Escherichia Coli Hemolytic-Uremic Syndrome (STEC-HUS) Completed NCT01410916 Phase 2, Phase 3 Eculizumab (Soliris®)
4 Safety and Efficacy Study of OMS721 in Patients With Atypical Hemolytic Uremic Syndrome Recruiting NCT03205995 Phase 3
5 Study of ALXN1210 in Children and Adolescents With Atypical Hemolytic Uremic Syndrome (aHUS) Recruiting NCT03131219 Phase 3
6 Single Arm Study of ALXN1210 in Complement Inhibitor Treatment-Naïve Adult and Adolescent Patients With Atypical Hemolytic Uremic Syndrome (aHUS) Recruiting NCT02949128 Phase 3
7 Eculizumab in Shiga-toxin Related Hemolytic and Uremic Syndrome Pediatric Patients - ECULISHU Recruiting NCT02205541 Phase 3 Eculizumab;Placebo
8 Phase III Randomized Study of SYNSORB Pk in Children With E. Coli-Associated Hemolytic Uremic Syndrome Terminated NCT00004465 Phase 3 SYNSORB Pk;Placebo
9 The Plasma Large-Volume Exchange RCT Withdrawn NCT01433003 Phase 3
10 Rituximab in Patients With Relapsed or Refractory TTP-HUS Unknown status NCT00531089 Phase 2 Rituximab
11 An Open-label, Multi-center Clinical Trial of Eculizumab in Adult Patients With Atypical Hemolytic-uremic Syndrome Completed NCT01194973 Phase 2 Eculizumab
12 An Open-Label, Multi-Center Clinical Trial of Eculizumab in Pediatric Patients With Atypical Hemolytic-Uremic Syndrome Completed NCT01193348 Phase 2 Eculizumab
13 Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-sensitive Atypical Hemolytic Uremic Syndrome (aHUS) Completed NCT00838513 Phase 2 eculizumab
14 Open Label Controlled Trial of Eculizumab in Adult Patients With Plasma Therapy-Resistant aHUS Completed NCT00844545 Phase 2 Eculizumab
15 Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Resistant aHUS Completed NCT00844844 Phase 2 Eculizumab
16 Open Label Controlled Trial of Eculizumab in Adolescent Patients With Plasma Therapy-Sensitive aHUS Completed NCT00844428 Phase 2 eculizumab
17 The Safety and Efficacy of Eculizumab in Japanese Patients With Atypical Hemolytic Uremic Syndrome (aHUS) Completed NCT01757431 Phase 2 Eculizumab
18 Study of Chimeric Monoclonal Antibodies to Shiga Toxins 1 and 2 Completed NCT01252199 Phase 2 cαStx1/cαStx2;Placebo
19 A Study of an Investigational Drug, Cemdisiran (ALN-CC5), in Patients With Atypical Hemolytic Uremic Syndrome Recruiting NCT03303313 Phase 2 Cemdisiran
20 Safety and Efficacy Study of OMS721 in Patients With Thrombotic Microangiopathies Recruiting NCT02222545 Phase 2
21 Complement Inhibition in aHUS Dialysis Patients Terminated NCT02464891 Phase 2 CCX168
22 Shiga Toxin Producing Escherichia Coli (STEC) Volume Expansion Not yet recruiting NCT03275792 Phase 1 D5-0.9%NS;Routine home oral rehydration
23 Complement Activation During Hemodialysis in Atypical Hemolytic Uraemic Syndrome as Underlying Kidney Disease Unknown status NCT00930423
24 Outbreak of Hemolytic Uremic Syndrome Linked to Escherichia Coli of Serotype O104:H4 Completed NCT01406288
25 A Retrospective, Observational, Non-interventional Trial to Assess Eculizumab Treatment Effect in Patients With Atypical Hemolytic Uremic Syndrome (aHUS) Completed NCT01770951
26 Haemolytic Uraemic Syndrome in Childhood: Clinical, Cognitive and Psychological Aspects Completed NCT01666548
27 To Characterize the Safety and Tolerability of Eculizumab in Two Japanese aHUS Patients Completed NCT01755429
28 Study of Repetitive Intestinal Lavage in Patients With EHEC Associated Hemorrhagic Colitis Completed NCT01561248 polyethylene glycol solution for daily bowel lavage.
29 The Role of Endothelium Dysfunction in Progression of CKD (Chronic Kidney Disease) After AKI (Acute Kidney Injury) Completed NCT00358306
30 Promising Bimarker Prediction of Outcome of HELLP Syndrome. Completed NCT03246542
31 Atypcial Hemolytic-Uremic Syndrome (aHUS) Registry Recruiting NCT01522183
32 Study of 'Vascular Competence' Profile and Endothelial Activation in the Hemolytic Uremic Syndrome in Children and Adults Recruiting NCT02904863
33 Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford Recruiting NCT01793168
34 Collection of Human Samples to Study Hairy Cell and Other Leukemias, and to Develop Recombinant Immunotoxins for Cancer Treatment Recruiting NCT01087333
35 Early Predictive Factors of Cardiac and Cerebral Involvement in TMA Active, not recruiting NCT02134171
36 The Role of Microparticles as a Biomarker Enrolling by invitation NCT02626663
37 aHUS Observational Long Term Follow-Up Terminated NCT01522170
38 International Registry and Biorepository for TMA(Thrombotic Microangiopathy) Terminated NCT00593229

Search NIH Clinical Center for Hemolytic-Uremic Syndrome

Cochrane evidence based reviews: hemolytic-uremic syndrome

Genetic Tests for Hemolytic-Uremic Syndrome

Genetic tests related to Hemolytic-Uremic Syndrome:

id Genetic test Affiliating Genes
1 Hemolytic Uremic Syndrome 29

Anatomical Context for Hemolytic-Uremic Syndrome

MalaCards organs/tissues related to Hemolytic-Uremic Syndrome:

39
Kidney, Endothelial, Liver, Brain, Lung, Heart, Monocytes

Publications for Hemolytic-Uremic Syndrome

Articles related to Hemolytic-Uremic Syndrome:

(show top 50) (show all 867)
id Title Authors Year
1
Hemolytic uremic syndrome as the presenting manifestation of WT1 mutation and Denys-Drash syndrome: a case report. ( 28720077 )
2017
2
Atypical hemolytic uremic syndrome triggered by varicella infection. ( 28725563 )
2017
3
Targeting renin-angiotensin system in malignant hypertension in atypical hemolytic uremic syndrome. ( 28356668 )
2017
4
Pathogenic Variants in Complement Genes and Risk of Atypical Hemolytic Uremic Syndrome Relapse after Eculizumab Discontinuation. ( 27799617 )
2017
5
Cobalamin disorder CblC presenting with hemolytic uremic syndrome and pulmonary hypertension. ( 28610805 )
2017
6
Angiopoietin-1 and -2 as markers for disease severity in hemolytic uremic syndrome induced by enterohemorrhagic Escherichia coli. ( 26945868 )
2017
7
Discontinuation of Peritoneal Dialysis after Late Initiation of Eculizumab in a Case of Familial Atypical Hemolytic-Uremic Syndrome: A Case Report. ( 28612003 )
2017
8
Gemcitabine-induced hemolytic-uremic syndrome treated with eculizumab or plasmapheresis: two case reportsa8c. ( 27879189 )
2017
9
Genome Sequence for Shiga Toxin-Producing Escherichia coli O26:H11, Associated with a Cluster of Hemolytic-Uremic Syndrome Cases in South Africa, 2017. ( 28935743 )
2017
10
Hemolytic-uremic Syndrome Complicating Acute Pancreatitis. ( 28904486 )
2017
11
Renal Recovery Years After Initial Diagnosis of Hemolytic Uremic Syndrome. ( 28931327 )
2017
12
Rare genetic variant in the CFB gene presenting as atypical hemolytic uremic syndrome and immune complex diffuse membranoproliferative glomerulonephritis, with crescents, successfully treated with eculizumab. ( 28210841 )
2017
13
Two cases of atypical hemolytic uremic syndrome (aHUS) and eosinophilic granulomatosis with polyangiitis (EGPA): a possible relationship. ( 28509134 )
2017
14
Aortic Valve Replacement as a Trigger of Atypical Hemolytic Uremic Syndrome. ( 28838521 )
2017
15
Murine systemic thrombophilia and hemolytic uremic syndrome from a factor H point mutation. ( 28057640 )
2017
16
Living Donor Kidney Transplantation in Atypical Hemolytic Uremic Syndrome: A Case Series. ( 28821363 )
2017
17
Should eculizumab be discontinued in patients with atypical hemolytic uremic syndrome? ( 28616209 )
2017
18
Turkish pediatric atypical hemolytic uremic syndrome registry: initial analysis of 146 patients. ( 28056875 )
2017
19
Successful Treatment of Enterohemorrhagic Escherichia coli-Induced Acute Encephalopathy and Hemolytic-Uremic Syndrome With Polymyxin-B Direct Hemoperfusion. ( 28597511 )
2017
20
Blood urea nitrogen to serum creatinine ratio as a prognostic factor in diarrhea-associated hemolytic uremic syndrome: a validation study. ( 28831612 )
2017
21
Hemolytic Uremic Syndrome-associated Encephalopathy Successfully Treated with Corticosteroids. ( 28943538 )
2017
22
A retrospective study of pregnancy-associated atypical hemolytic uremic syndrome. ( 28911789 )
2017
23
Blood urea nitrogen to serum creatinine ratio is an accurate predictor of outcome in diarrhea-associated hemolytic uremic syndrome, a preliminary study. ( 28078430 )
2017
24
Clinical characteristics and long-term outcome of diarrhea-associated hemolytic uremic syndrome: a single center experience. ( 28074307 )
2017
25
Atypical Hemolytic Uremic Syndrome: Achieving Positive Patient Outcomes With Early Diagnosis and Appropriate Managementa8c. ( 28738049 )
2017
26
Atypical Hemolytic Uremic Syndrome: A Brief Review. ( 28626544 )
2017
27
A devastating case of diarrhea-associated hemolytic uremic syndrome associated with extensive cerebral infarction; why we need to do better. ( 28599619 )
2017
28
Factor H autoantibody is associated with atypical hemolytic uremic syndrome in children in the United Kingdom and Ireland. ( 28750931 )
2017
29
Late Onset Cobalamin Disorder and Hemolytic Uremic Syndrome: A Rare Cause of Nephrotic Syndrome. ( 28835862 )
2017
30
Critical appraisal of eculizumab for atypical hemolytic uremic syndrome. ( 27110144 )
2016
31
From Gestational Hypertension and Preeclampsia to Atypical Hemolytic Uremic Syndrome. ( 27054930 )
2016
32
Direct evidence of complement activation in HELLP syndrome: A link toA atypical hemolytic uremic syndrome. ( 26921648 )
2016
33
Clinical Practice Guidelines for the Management of Atypical Hemolytic Uremic Syndrome in Korea. ( 27550478 )
2016
34
Whole-Genome Characterization and Strain Comparison of VT2f-Producing Escherichia coli Causing Hemolytic Uremic Syndrome. ( 27584691 )
2016
35
Atypical hemolytic uremic syndrome: a clinical conundrum. ( 27139899 )
2016
36
C3 mesangial proliferative glomerulonephritis initially presenting with atypical hemolytic uremic syndrome: a case report. ( 27460033 )
2016
37
Disturbed sialic acid recognition on endothelial cells and platelets in complement attack causes atypical hemolytic uremic syndrome. ( 27006390 )
2016
38
Indications of underdiagnosis of Atypical Hemolytic Uremic Syndrome in a cohort referred to the Coagulation Unit in Malmo, Sweden, for analysis of ADAMTS13 2007-2012. ( 27175932 )
2016
39
Small-molecule Factor D inhibitors selectively block the alternative pathway of complement in paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome. ( 27810992 )
2016
40
Postoperative Atypical Hemolytic Uremic Syndrome Treated Successfully with Eculizumab. ( 27150874 )
2016
41
Late onset of de novo atypical hemolytic-uremic syndrome presented on a simultaneous pancreas and kidney transplant recipient successfully treated with eculizumab. ( 27012439 )
2016
42
Direct cardiac involvement in childhood hemolytic-uremic syndrome: case report and review of the literature. ( 27659663 )
2016
43
A Case Report and Literature Review of Eculizumab Withdrawal in Atypical Hemolytic-Uremic Syndrome. ( 27974740 )
2016
44
The Alternative Pathway of Complement and the Evolving Clinical-Pathophysiological Spectrum of Atypical Hemolytic Uremic Syndrome. ( 27524217 )
2016
45
Cerebral Hemodynamics in Patients with Hemolytic Uremic Syndrome Assessed by Susceptibility Weighted Imaging and Four-Dimensional Non-Contrast MR Angiography. ( 27802295 )
2016
46
Prevention of recurrence of atypical hemolytic uremic syndrome post renal transplant with the use of higher-dose eculizumaba8c. ( 27616760 )
2016
47
No association between dysplasminogenemia with p.Ala620Thr mutation and atypical hemolytic uremic syndrome. ( 27194432 )
2016
48
Clinical guides for atypical hemolytic uremic syndrome in Japan. ( 27460397 )
2016
49
Development of camelid single chain antibodies against Shiga toxin type 2 (Stx2) with therapeutic potential against Hemolytic Uremic Syndrome (HUS). ( 27118524 )
2016
50
Thrombotic Thrombocytopenic Purpura and Atypical Hemolytic Uremic Syndrome Microangiopathy in Pregnancy. ( 27648610 )
2016

Variations for Hemolytic-Uremic Syndrome

Expression for Hemolytic-Uremic Syndrome

Search GEO for disease gene expression data for Hemolytic-Uremic Syndrome.

Pathways for Hemolytic-Uremic Syndrome

GO Terms for Hemolytic-Uremic Syndrome

Cellular components related to Hemolytic-Uremic Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.91 C3 C5 CD46 CFB CFH CFHR1
2 extracellular space GO:0005615 9.65 ADAMTS13 C3 C5 CD40LG CFB CFH
3 blood microparticle GO:0072562 9.55 C3 CFB CFH CFHR1 CFHR3
4 extracellular region GO:0005576 9.36 ADAMTS13 C3 C5 CD40LG CFB CFH

Biological processes related to Hemolytic-Uremic Syndrome according to GeneCards Suite gene sharing:

(show all 12)
id Name GO ID Score Top Affiliating Genes
1 proteolysis GO:0006508 9.83 ADAMTS13 C3 CD46 CFB CFI
2 immune system process GO:0002376 9.8 C3 C5 CD46 CFB
3 innate immune response GO:0045087 9.73 C3 C5 CD46 CFB CFH CFI
4 blood coagulation GO:0007596 9.69 ADAMTS13 THBD VWF
5 complement activation, classical pathway GO:0006958 9.67 C3 C5 CD46 CFI
6 platelet activation GO:0030168 9.62 ADAMTS13 CD40LG DGKE VWF
7 hemostasis GO:0007599 9.58 ADAMTS13 THBD VWF
8 complement activation GO:0006956 9.55 C3 C5 CFB CFH CFHR1
9 positive regulation of vascular endothelial growth factor production GO:0010575 9.48 C3 C5
10 positive regulation of interleukin-10 production GO:0032733 9.46 CD40LG CD46
11 complement activation, alternative pathway GO:0006957 9.35 C3 C5 CFB CFH CFHR5
12 regulation of complement activation GO:0030449 9.28 C3 C5 CD46 CFB CFH CFHR1

Molecular functions related to Hemolytic-Uremic Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 complement binding GO:0001848 8.62 CD46 CFB

Sources for Hemolytic-Uremic Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....