MCID: HMP018
MIFTS: 34

Hemophilic Arthropathy malady

Category: Rare diseases

Aliases & Classifications for Hemophilic Arthropathy

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Aliases & Descriptions for Hemophilic Arthropathy:

Name: Hemophilic Arthropathy 48 68

Classifications:



Summaries for Hemophilic Arthropathy

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MalaCards based summary: Hemophilic Arthropathy is related to arthropathy and hemophilia. An important gene associated with Hemophilic Arthropathy is HFE (Hemochromatosis), and among its related pathways are Osteoblast Signaling and Apoptosis and survival Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway. Affiliated tissues include bone, and related mouse phenotypes are no phenotypic analysis and behavior/neurological.

Related Diseases for Hemophilic Arthropathy

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Diseases related to Hemophilic Arthropathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 55)
idRelated DiseaseScoreTop Affiliating Genes
1arthropathy10.9
2hemophilia10.1
3listeria meningitis10.1HFE, TNFRSF11B
4cocaine dependence10.0TNFRSF11A, TNFRSF11B
5patellofemoral pain syndrome10.0PTGS2, TNFRSF11A
6osteoporosis10.0
7osteoarthritis10.0
8aneurysm10.0
9cortical blindness10.0TNFRSF11B, TNFSF11
10peripheral scars of retina10.0TNFRSF11B, TNFSF11
11respiratory system disease10.0PTGS2, TNFRSF11B
12breast intracanalicular fibroadenoma9.9PTGS2, TNFSF11
13acrorenal syndrome9.9TNFRSF11B, TNFSF11
14extrahepatic bile duct leiomyosarcoma9.9TNFRSF11A, TNFSF11
15statin toxicity9.9PTGS2, TNFSF11
16exudative vitreoretinopathy 49.9TNFRSF11B, TNFSF11
17post-traumatic stress disorder9.9TNFRSF11B, TNFSF11
18chromosome 16q22 deletion syndrome9.9TNFRSF11A, TNFSF11
19celiac disease9.9TNFRSF11B, TNFSF11
20vascular dementia9.9TNFRSF11B, TNFSF11
21ceroid lipofuscinosis, neuronal, kufs type, adult onset9.8TNFRSF11B, TNFSF11
22hemophilia a9.8
23arthritis9.8
24leukemia9.8
25poliomyelitis9.8
26hemarthrosis9.8
27septic arthritis9.8
28synovium cancer9.8COMP, TNFRSF11B, TNFSF11
29molybdenum cofactor deficiency a9.8COMP, TNFRSF11B, TNFSF11
30phka2-related phosphorylase kinase deficiency9.8TNFRSF11A, TNFRSF11B, TNFSF11
31birk-barel mental retardation dysmorphism syndrome9.8TNFRSF11A, TNFRSF11B, TNFSF11
32osteopetrosis, autosomal recessive 79.8TNFRSF11A, TNFRSF11B, TNFSF11
33pancreatic ductal adenocarcinoma9.8TNFRSF11A, TNFSF11
34epilepsy, idiopathic generalized 149.8TNFRSF11A, TNFRSF11B, TNFSF11
35polyomavirus allograft nephropathy9.8TNFRSF11A, TNFRSF11B, TNFSF11
36microcephaly 10, primary, autosomal recessive9.8TNFRSF11A, TNFRSF11B, TNFSF11
37maroteaux stanescu cousin syndrome9.8TNFRSF11A, TNFRSF11B, TNFSF11
38bronchus cancer9.7TNFRSF11A, TNFRSF11B, TNFSF11
39bulbomembranous urethral cancer9.7TNFRSF11A, TNFRSF11B, TNFSF11
40glossitis9.7TNFRSF11A, TNFRSF11B, TNFSF11
41chromosomal disease9.7TNFRSF11A, TNFRSF11B, TNFSF11
42dysbaric osteonecrosis9.7TNFRSF11A, TNFRSF11B, TNFSF11
43ischemic bone disease9.7TNFRSF11A, TNFRSF11B, TNFSF11
44preretinal fibrosis9.7TNFRSF11A, TNFRSF11B, TNFSF11
45intrahepatic cholestasis9.7TNFRSF11A, TNFRSF11B, TNFSF11
46bladder papillary transitional cell neoplasm9.7TNFRSF11A, TNFRSF11B, TNFSF11
47histiocytosis9.7TNFRSF11A, TNFRSF11B, TNFSF11
48fungal gastritis9.7TNFRSF11B, TNFSF11
49autistic disorder9.7PTGS2, TNFRSF11A, TNFSF11
50carnitine deficiency, systemic primary9.7TNFRSF11A, TNFRSF11B, TNFSF11

Graphical network of the top 20 diseases related to Hemophilic Arthropathy:



Diseases related to hemophilic arthropathy

Symptoms & Phenotypes for Hemophilic Arthropathy

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MGI Mouse Phenotypes related to Hemophilic Arthropathy according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030128.8HFE, PTGS2, TNFRSF11A, TNFSF11
2MP:00053868.5COMP, HFE, PTGS2, TNFRSF11A, TNFSF11
3MP:00053718.4COMP, HFE, TNFRSF11A, TNFRSF11B, TNFSF11
4MP:00053978.4HFE, PTGS2, TNFRSF11A, TNFRSF11B, TNFSF11
5MP:00053787.9COMP, HFE, PTGS2, TNFRSF11A, TNFRSF11B, TNFSF11
6MP:00053877.9COMP, HFE, PTGS2, TNFRSF11A, TNFRSF11B, TNFSF11
7MP:00053907.5COMP, PTGS2, TNFRSF11A, TNFRSF11B, TNFSF11

Drugs & Therapeutics for Hemophilic Arthropathy

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Drugs for Hemophilic Arthropathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 18)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Bevacizumabapproved, investigationalPhase 42020216974-75-3
Synonyms:
216974-75-3
Avastin
Avastin (TN)
Bevacizumab
Bevacizumab (genetical recombination)
 
Bevacizumab (genetical recombination) (JAN)
D06409
R-435
anti-VEGF monoclonal antibody
antiVEGF
bevacizumab
2
Triamcinoloneapproved, vet_approvedPhase 4510124-94-731307
Synonyms:
(8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
11-beta,16-alpha,17-alpha,21-Tetrahydroxy-9-alpha-fluoro-1,4-pregnadiene-3,20-dione
11.Beta.,16.alpha.,17.alpha., 21-Tetrahydroxy-9.alpha.-fluoro-1,4-pregnadiene-3,20-dione
11.beta.,16.alpha.,17.alpha.,21-Tetrahydroxy-9.alpha.-fluoro-1,4-pregnadiene-3,20-dione
11β,16α,17α,21-tetrahydroxy-9α-fluoro-1,4-pregnadiene-3,20-dione
124-94-7
4-08-00-03629 (Beilstein Handbook Reference)
83474-03-7
9-Fluoro-11,16,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-alpha-Fluoro-11-beta,16-alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9-alpha-Fluoro-16-alpha-hydroxyprednisolone
9-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9.Alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahy
9.Alpha.-Fluoro-11.beta.,16.alpha.,17.alpha., 21-tetrahydroxypregna-1,4-diene-3,20-d
9.alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione
9.alpha.-Fluoro-11.beta.,16.alpha.,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9.alpha.-Fluoro-11.beta.,16.alpha.,17.alpha.,21-tetrahydroxypregna-1,4-diene-3,20-dione
9.alpha.-Fluoro-16.alpha.-hydroxyprednisolone
9alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxy-1,4-pregnadiene-3,20-dione
9alpha-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9alpha-Fluoro-16alpha-hydroxyprednisolone
9α-fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione
9α-fluoro-11β,16α,17α,21-tetrahydroxypregna-1,4-diene-3,20-dione
9α-fluoro-16α-hydroxyprednisolone
AC-2072
AC1L1LDH
AC1Q5HJC
Adcortyl
Aristocort
Aristocort A
Aristocort Tablets
Aristogel
Aristospan
Azmacort
BPBio1_000154
BRD-K77554836-001-03-3
BRN 2341955
BSPBio_000140
Bio-0662
C21H27FO6
CHEMBL1451
CID31307
CL 19823
Celeste
Cinolone
Cinolone-T
D00385
D014221
DB00620
Delphicort
EINECS 204-718-7
EU-0101179
Fluoxiprednisolone
Fluoxyprednisolone
Flutex
Fougera
HMS1568G22
HMS2090D12
HSDB 3194
Kenacort
Kenacort (TN)
Kenacort-A
Kenacort-AG
Kenacort-Ag
Kenalog
Kenalog in Orabase
Kenalog-10
Kenalog-40
Kenalog-H
LS-698
Ledercort
Lopac0_001179
 
MLS000028542
MLS001066543
MLS002695935
MolPort-002-528-981
Mycolog
NCGC00021580-03
NCGC00021580-04
NCGC00021580-05
NCGC00021580-06
NCGC00021580-07
NCI60_000750
NSC 13397
NSC13397
Nasacort
Nasacort Aq
Nasacort Hfa
Omcilon
Omicilon
Oracort
Oralone
Orion
Polcortolon
Pregna-1,4-diene-3,20-dio
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,16,17,21-tetrahydroxy-, (11beta,16alpha)
Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,16alpha,17,21-tetrahydroxy- (8CI)
Prestwick0_000120
Prestwick1_000120
Prestwick2_000120
Prestwick3_000120
Prestwick_438
Rodinolone
S1933_Selleck
SK-Triamcinolone
SMP1_000300
SMR000058333
SPBio_002079
Sk-Triamcinolone
T6376_SIGMA
TRIAMCINOLONE (SEE ALSO TRIAMCINOLONE ACETONIDE (76-25-5) AND TRIAMCINOLONE DIACETATE (67-78-7))
Tiamcinolonum
Tiamcinolonum [INN-Latin]
Tri-Nasal
Triacet
Triacort
Triam-Tablinen
Triamcet
Triamcinalone
Triamcinlon
Triamcinolon
Triamcinolona
Triamcinolona [INN-Spanish]
Triamcinolone (JP15/USP/INN)
Triamcinolone [USAN:INN:BAN:JAN]
Triamcinolone acetonide
Triamcinolone diacetate
Triamcinolone hexacetonide
Triamcinolonum
Triamcinolonum [INN]
Triatex
Tricortale
Triderm
Trilone
Tristoject
Trymex
UNII-1ZK20VI6TY
Vetalog
Volon
Volon A
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ GQ
ZINC03882036
droxypregna-1,4-diene-3,20-dione
ione
nchembio.2007.53-comp7
triamcinolone
3
Hyaluronic acidapproved, vet_approvedPhase 44699004-61-953477741, 24759
Synonyms:
Hyaluronan
Hyaluronate
Hyaluronic acid
Hylartil
Hyruan Plus
Luronit
 
Macronan
Mucoitin
Nutra-HAF
Q 5AQ
Sepracoat
Sepragel Sinus
Sofast
Synvisc
4
RopivacaineapprovedPhase 479384057-95-471273, 175805
Synonyms:
(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide
(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride
(S)-(−)-1-propyl-2',6'-pipecoloxylidide
(S)-ropivacaine
84057-95-4
98717-15-8
AC1L41QM
AC1L41QN
BIDD:GT0203
C07532
C17H26N2O.HCl
CHEBI:8890
CHEMBL1077896
CID175804
CID175805
CPD000469137
D08490
I14-176
L-N-n-propylpipecolic acid-2,6-xylidide
LS-113954
 
MLS001401363
MolPort-003-983-292
NCGC00164597-01
Naropin
Naropin (TN)
ROPIVACAINE HCl
Ropivacaina
Ropivacaina [INN-Spanish]
Ropivacaina [Spanish]
Ropivacaine
Ropivacaine [INN]
Ropivacaine hydrochloride
Ropivacaine monohydrochloride
Ropivacainum
Ropivacainum [INN-Latin]
S-Ropivacaine
SAM001246524
SMR000469137
ST51051452
ropivacaine monohydrochloride,
ropivacaine monohydrochloride, (S)-isomer
5Angiogenesis InhibitorsPhase 44257
6Angiogenesis Modulating AgentsPhase 44185
7Triamcinolone diacetatePhase 4510
8Triamcinolone hexacetonidePhase 4510
9ViscosupplementsPhase 4390
10Factor VIIIPhase 4316
11triamcinolone acetonidePhase 4510
12Adjuvants, ImmunologicPhase 42554
13HylanPhase 446
14Protective AgentsPhase 47443
15Coagulants1500
16Thrombin304
17Hemostatics1443
18Soy BeanNutraceutical554

Interventional clinical trials:

(show all 26)
idNameStatusNCT IDPhase
1Intra-articular Bevacizumab for Recurrent Hemarthroses at Target Joints With Chronic Hemophilic SynovitisUnknown statusNCT02060305Phase 4
2Viscosupplementation in Patients With Hemophilic ArthropathyCompletedNCT01748201Phase 4
3Impact of Conservative Treatment by Custom-made Orthoses in Patients With Haemophilic Ankle ArthropathyCompletedNCT00638001Phase 4
4Validation of Ultrasound as a Diagnostic Tool for Assessment of Hemophilic Arthropathy of Knees and AnklesCompletedNCT01232634Phase 2
5A Proof-of-Concept Study of AC-201 Controlled-Release Tablet (CR Tablet) in Patients With Hemophilic ArthropathyRecruitingNCT02994147Phase 2
6Biomechanical Determinants and Patterns Associated to the Pathophysiological Cascade of Ankle Arthropathy in Children With Haemophilia: Non-invasive In-vivo Measurement of Foot Joints in Children With Haemophilia During Gait.Unknown statusNCT02229331
7Platelet-Rich Plasma Intra-Articular Injection in Treating Hemophilic ArthropathyCompletedNCT02601170
8Bilateral Deficit Phenomenon in Patients With Haemophilic ArthropathyCompletedNCT02165462
9Manual Therapy in Haemophilic Arthropathy of the KneeCompletedNCT02198014
10Physiotherapy in the Haemophilic Arthropathy of the Elbow.CompletedNCT02198040
11Gait Evaluation in Haemophiliac PatientsCompletedNCT00824798
12Exploratory Pilot Study of Physical Activity Monitoring in Adult Patients With Haemophilia A by Means of AccelerometryCompletedNCT02253693
13Educational Physiotherapy in HaemophiliaCompletedNCT02825706
14Study to Evaluate the Use of Ultrasound in the Diagnosis of Hemophilic Joint DiseaseCompletedNCT00212485
15Epidemiological Study on Haemophilia Care and Orthopaedic Status in Developing CountriesCompletedNCT01503567
16Myofascial Therapy in Patients With Hemophilic ArthropathyRecruitingNCT02433782
17Efficacy and Safety of Shea Nut Oil in Hemophilic ArthropathyRecruitingNCT02569359
18TGA (Thrombin Generation Assay) and Prophylaxis in HaemophiliaRecruitingNCT02781766
19Assessment of Proprioceptive and Functional Characteristics in Patients With HemophiliaRecruitingNCT02165592
20Personalized Prophylactic Treatment With Advate® in Severe or Moderate Haemophilia A PatientsRecruitingNCT02622646
21Ultrasonography in Hemophilic Joint Disease and Serum MarkersRecruitingNCT02634918
22Joint Outcome Study Continuation for Children With Severe Factor VIII DeficiencyEnrolling by invitationNCT01000844
23Effectiveness of the Myofascial Therapy in the Hemophilic Arthropathy of AnkleNot yet recruitingNCT02825667
24Fascial Therapy in Elbow Hemophilic ArthropathyNot yet recruitingNCT03009591
25Osteoporosis and MRI Study in HemophiliaTerminatedNCT01460147
26Individually Tailored Prophylaxis in Patients With Severe Hemophilia ATerminatedNCT00995046

Search NIH Clinical Center for Hemophilic Arthropathy

Genetic Tests for Hemophilic Arthropathy

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Anatomical Context for Hemophilic Arthropathy

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MalaCards organs/tissues related to Hemophilic Arthropathy:

36
Bone

Publications for Hemophilic Arthropathy

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Articles related to Hemophilic Arthropathy:

(show top 50)    (show all 142)
idTitleAuthorsYear
1
Pathophysiology of hemophilic arthropathy and potential targets for therapy. (27890816)
2017
2
Intra-articular injections of mesenchymal stem cells (MSCs) as a treatment for hemophilic arthropathy. (27322636)
2016
3
Soluble vascular cell adhesion molecular-1 is a potential biological indicator of hemophilic arthropathy. (27861372)
2016
4
Advances and challenges in hemophilic arthropathy. (26805902)
2016
5
The F8(-/-) rat as a model of hemophilic arthropathy. (27060449)
2016
6
Synovium and cartilage biomarkers in hemophilic arthropathy. (26761216)
2016
7
Altered collagen turnover in factor VIII-deficient rats with hemophilic arthropathy identifies potential novel serological biomarkers in hemophilia. (27681457)
2016
8
Assessment of Hemophilic Arthropathy by Ultrasound: Where Do We Stand? (27124619)
2016
9
Radiosynoviorthesis in hemophilic arthropathy: pathologic blood pool imaging on pre-therapeutic bone scintigraphy is not a predictor of treatment success. (27796541)
2016
10
Total ankle replacement or ankle fusion in painful advanced hemophilic arthropathy of the ankle. (26358145)
2015
11
Vascular remodeling underlies rebleeding in hemophilic arthropathy. (26257191)
2015
12
Subjective results of joint lavage and viscosupplementation in hemophilic arthropathy. (26207096)
2015
13
The long-term effects of radioactive phosphorous synoviorthesis on hemophilic arthropathy. (25976470)
2015
14
Hemophilic arthropathy of the elbow: prophylaxis, imaging, and the role of invasiveA management. (26385390)
2015
15
Patient dissatisfaction after total knee arthroplasty for hemophilic arthropathy and osteoarthritis (non-hemophilia patients). (26561009)
2015
16
Total Knee Arthroplasty in Hemophilic Arthropathy. (26665252)
2015
17
Diagnostic accuracy of ultrasound for assessment of hemophilic arthropathy: MRI correlation. (25714320)
2015
18
Inflammation is key to hemophilic arthropathy. (26542253)
2015
19
Manual therapy in the treatment of ankle hemophilic arthropathy. A randomized pilot study. (24678758)
2014
20
Osteoid osteoma of the elbow mimicking hemophilic arthropathy. (24749122)
2014
21
Optimal management of hemophilic arthropathy and hematomas. (25378964)
2014
22
The Effectiveness of Tools for Monitoring Hemophilic Arthropathy. (25000469)
2014
23
Hemophilic arthropathy: a review of imaging and staging. (24332203)
2013
24
Outcome of Total Knee Arthroplasty in Hemophilic Arthropathy. (23958233)
2013
25
Viscosupplementation in patients with hemophilic arthropathy. (24453636)
2013
26
Hemophilic arthropathy of shoulder joints: clinical, radiographic, and ultrasonographic characteristics of seventy patients. (23553306)
2013
27
Arthroscopic ankle arthrodesis in hemophilic arthropathy. (23478887)
2013
28
Outcome of total knee arthroplasty combined patelloplasty for end-stage type A hemophilic arthropathy. (21342764)
2012
29
Impact of ankle osteoarthritis on the energetics and mechanics of gait: the case of hemophilic arthropathy. (22381586)
2012
30
RANK-RANKL-OPG in hemophilic arthropathy: from clinical and imaging diagnosis to histopathology. (22753650)
2012
31
Intra-articular injection of mesenchymal stem cells expressing coagulation factor ameliorates hemophilic arthropathy in factorA VIII-deficient mice. (22784361)
2012
32
Total knee arthroplasty in a patient with hemophilic arthropathy and high-titer inhibitors: a cost analysis. (22153945)
2012
33
Osteoporosis/osteopenia and hemophilic arthropathy in severe hemophilic patients. (22292576)
2012
34
Hemophilic arthropathy in patients with von Willebrand disease. (23010260)
2012
35
Shoulder arthroplasty in hemophilic arthropathy. (21167746)
2011
36
Arthroscopic ankle arthrodesis for hemophilic arthropathy: two cases report. (21295463)
2011
37
Evaluation of osteoporosis in hemophilic arthropathy patients: correlation with disease severity and serum trace minerals. (22007335)
2011
38
The efficacy of magnetic resonance imaging and x-ray in the evaluation of response to radiosynovectomy in patients with hemophilic arthropathy. (23487524)
2011
39
Hemophilic arthropathy of the elbow. (21501786)
2011
40
Synoviorthesis induced by rifampicin in hemophilic arthropathy: a report of 24 treated joints. (21318571)
2011
41
Unraveling hemophilic arthropathy. (21350060)
2011
42
End-stage hemophilic arthropathy in a patient from a developing nation. (20808176)
2010
43
Hemophilic arthropathy. (21623422)
2010
44
Increased bone resorption is implicated in the pathogenesis of bone loss in hemophiliacs: correlations with hemophilic arthropathy and HIV infection. (19488753)
2010
45
Blood-induced joint disease: the pathophysiology of hemophilic arthropathy. (20586922)
2010
46
A long term results of external beam radiation therapy in hemophilic arthropathy of the ankle in children. (21165288)
2010
47
Effects of electrical stimulation on muscle trophism in patients with hemophilic arthropathy. (19887218)
2009
48
Total knee arthroplasty in hemophilic arthropathy: efficiency of clotting factor usage in multijoint procedures. (19682237)
2009
49
The combination of the biomarkers urinary C-terminal telopeptide of type II collagen, serum cartilage oligomeric matrix protein, and serum chondroitin sulfate 846 reflects cartilage damage in hemophilic arthropathy. (19116938)
2009
50
Rhenium-186 hydroxyethylidenediphosphonate (186Re HEDP) for the treatment of hemophilic arthropathy: first results. (17710012)
2007

Variations for Hemophilic Arthropathy

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Expression for genes affiliated with Hemophilic Arthropathy

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Search GEO for disease gene expression data for Hemophilic Arthropathy.

Pathways for genes affiliated with Hemophilic Arthropathy

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Pathways related to Hemophilic Arthropathy according to GeneCards Suite gene sharing:

(show all 13)
idSuper pathwaysScoreTop Affiliating Genes
19.1TNFRSF11B, TNFSF11
2
Show member pathways
9.0TNFRSF11A, TNFSF11
39.0TNFRSF11A, TNFSF11
48.5PTGS2, TNFRSF11A, TNFSF11
58.5PTGS2, TNFRSF11A, TNFSF11
6
Show member pathways
8.5TNFRSF11A, TNFRSF11B, TNFSF11
7
Show member pathways
8.5TNFRSF11A, TNFRSF11B, TNFSF11
88.5TNFRSF11A, TNFRSF11B, TNFSF11
98.5TNFRSF11A, TNFRSF11B, TNFSF11
10
Show member pathways
8.5TNFRSF11A, TNFRSF11B, TNFSF11
118.5TNFRSF11A, TNFRSF11B, TNFSF11
12
Show member pathways
8.0PTGS2, TNFRSF11A, TNFRSF11B, TNFSF11
13
Show member pathways
8.0PTGS2, TNFRSF11A, TNFRSF11B, TNFSF11

GO Terms for genes affiliated with Hemophilic Arthropathy

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Cellular components related to Hemophilic Arthropathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056159.0COMP, HFE, TNFRSF11B, TNFSF11
2integral component of plasma membraneGO:00058878.1HFE, TNFRSF11A, TNFRSF11B, TNFSF11

Biological processes related to Hemophilic Arthropathy according to GeneCards Suite gene sharing:

(show all 15)
idNameGO IDScoreTop Affiliating Genes
1apoptotic signaling pathwayGO:009719010.0TNFRSF11A, TNFRSF11B
2response to cytokineGO:003409710.0PTGS2, TNFRSF11A
3response to radiationGO:00093149.9PTGS2, TNFRSF11A
4response to tumor necrosis factorGO:00346129.9PTGS2, TNFRSF11A
5mammary gland alveolus developmentGO:00607499.7TNFRSF11A, TNFSF11
6monocyte chemotaxisGO:00025489.7TNFRSF11A, TNFSF11
7ossificationGO:00015039.7TNFRSF11A, TNFSF11
8osteoclast differentiationGO:00303169.7TNFRSF11A, TNFSF11
9positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signalingGO:00718489.7TNFRSF11A, TNFSF11
10positive regulation of fever generation by positive regulation of prostaglandin secretionGO:00718129.7TNFRSF11A, TNFSF11
11positive regulation of sequence-specific DNA binding transcription factor activityGO:00510919.7TNFRSF11A, TNFSF11
12TNFSF11-mediated signaling pathwayGO:00718479.6TNFRSF11A, TNFSF11
13inflammatory responseGO:00069549.5PTGS2, TNFRSF11A, TNFRSF11B
14response to lipopolysaccharideGO:00324969.4PTGS2, TNFRSF11A, TNFRSF11B
15tumor necrosis factor-mediated signaling pathwayGO:00332098.5TNFRSF11A, TNFRSF11B, TNFSF11

Molecular functions related to Hemophilic Arthropathy according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1tumor necrosis factor-activated receptor activityGO:00050319.3TNFRSF11A, TNFRSF11B

Sources for Hemophilic Arthropathy

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet