MCID: HMR004
MIFTS: 52

Hemorrhagic Fever with Renal Syndrome malady

Categories: Infectious diseases, Rare diseases, Skin diseases, Nephrological diseases

Aliases & Classifications for Hemorrhagic Fever with Renal Syndrome

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Sources:
11Disease Ontology, 13DISEASES, 37MeSH, 66UMLS, 52Orphanet, 28ICD10, 30ICD9CM, 43NCIt, 29ICD10 via Orphanet, 38MESH via Orphanet, 67UMLS via Orphanet, 60SNOMED-CT
See all MalaCards sources

Aliases & Descriptions for Hemorrhagic Fever with Renal Syndrome:

Name: Hemorrhagic Fever with Renal Syndrome 11 13 37 66
Hantavirosis 52 66
Hemorrhagic Fever-Renal Syndrome 52
Hemorrhagic Nephrosonephritis 11
 
Hemorrhagic Fever, Russian 11
Puumala Virus Nephropathy 11
Hantavirus Fever 52
Hfrs 11

Characteristics:

Orphanet epidemiological data:

52
hantavirosis:
Prevalence: 1-9/1000000 (Europe); Age of onset: All ages; Age of death: any age

Classifications:



External Ids:

Disease Ontology11 DOID:11266
ICD1028 A98.5
ICD9CM30 078.6
MeSH37 D006480
NCIt43 C84753
Orphanet52 ORPHA340
ICD10 via Orphanet29 A98.5+, N08.0*
MESH via Orphanet38 C535630, D006480
UMLS via Orphanet67 C0019101, C2930957

Summaries for Hemorrhagic Fever with Renal Syndrome

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Disease Ontology:11 A viral infectious disease that is a hemorrhagic fever, located in kidney, has material basis in hantaan virus, has material basis in dobrava-belgrade virus, has material basis in seoul virus, or has material basis in puumala virus, which are carried and transmitted by rodents. the infection has symptom headache, has symptom fever, has symptom muscle pains, has symptom facial flush, has symptom petechiae, has symptom hemorrhagic features, has symptom proteinuria, and has symptom renal failure.

MalaCards based summary: Hemorrhagic Fever with Renal Syndrome, also known as hantavirosis, is related to scrub typhus and hemophagocytic lymphohistiocytosis, and has symptoms including abnormality of temperature regulation, renal insufficiency and abnormality of the renal tubule. An important gene associated with Hemorrhagic Fever with Renal Syndrome is CD40LG (CD40 Ligand), and among its related pathways are IgA-Producing B Cells in the Intestine and Malaria. Affiliated tissues include kidney, kidney and t cells, and related mouse phenotype hematopoietic system.

Related Diseases for Hemorrhagic Fever with Renal Syndrome

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Diseases related to Hemorrhagic Fever with Renal Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 290)
idRelated DiseaseScoreTop Affiliating Genes
1scrub typhus30.6ALB, TNF
2hemophagocytic lymphohistiocytosis30.4HLA-DRB1, IL6, TNF
3myocardial infarction28.8ALB, CRP, IL6, SERPINC1, TNF
4korean hemorrhagic fever11.7
5hemorrhagic fever11.1
6nephropathia epidemica10.8
7aortic arch interruption10.8IL6, TNF
8cutaneous leishmaniasis10.8IL6, TNF
9solitary osseous plasmacytoma10.7B2M, IL6
10maligant granulosa cell tumor of ovary10.7IL6, TNF
11aneurysm of sinus of valsalva10.7CRP, IL6
12hemometra10.7IL6, TNF
13tricho odonto onycho dermal syndrome10.7IL6, TNF
14keratoconjunctivitis sicca10.7CD40LG, TNF
15monoclonal paraproteinemia10.7CD40LG, IL6
16carbon baby syndrome10.7CRP, IL6
17scrotum paget's disease10.7IL6, TNF
18hantavirus pulmonary syndrome10.7
19night blindness10.7CD40LG, TNF
20bone cancer10.7CD40LG, CRP
21dehydration polycythemia10.7CD40LG, CRP
22brucella abortus brucellosis10.7CD40LG, TNF
23calcinosis10.7CD40LG, CRP
24disease_ontology10.7CD40LG, IL6
25angioma hereditary neurocutaneous10.6CRP, IL6
26common variable immunodeficiency10.6HLA-DRB1, TNF
27midline interhemispheric variant of holoprosencephaly10.6CRP, IL6
28fallopian tube leiomyosarcoma10.6CD40LG, CRP
29parsonage turner syndrome10.6HLA-DRB1, TNF
30weber syndrome10.6HLA-DRB1, TNF
31antigen-peptide-transporter 2 deficiency10.6IL6, TNF
32myopathy-growth delay-intellectual disability-hypospadias syndrome10.6HLA-DRB1, TNF
33krieble bixler syndrome10.6HLA-DRB1, TNF
34lemierre's syndrome10.6CRP, TNF
35hyperthyroxinemia10.6CRP, TNF
36small intestinal vasoactive intestinal peptide producing tumor10.6CD40LG, CRP
37hypothyroidism10.6IL6, TNF
38primary biliary cirrhosis10.6B2M, IL6, TNF
39ethmoid sinus adenoid cystic carcinoma10.6IL6, TNF
40beach ear10.6CD40LG, CRP
41ehlers-danlos syndrome, musculocontractural type10.6B2M, IL6, TNF
42post-traumatic stress disorder10.6CD40LG, CRP
43cataract 2510.6ALB, B2M
44heart lymphoma10.6B2M, CD40LG, IL6
45non-secretory myeloma10.6CD40LG, IL6, TNF
46kaposi sarcoma10.5HLA-DRB1, IL6
47lipid-rich breast carcinoma10.5B2M, CD40LG, IL6
48panner disease10.5CRP, IL6, TNF
49leukostasis10.5CD40LG, IL6, TNF
50foodborne botulism10.5CD40LG, IL6, TNF

Graphical network of the top 20 diseases related to Hemorrhagic Fever with Renal Syndrome:



Diseases related to hemorrhagic fever with renal syndrome

Symptoms for Hemorrhagic Fever with Renal Syndrome

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Symptoms:

 11 52 (show all 38)
  • headache
  • fever
  • muscle pains
  • facial flush
  • petechiae
  • hemorrhagic features
  • proteinuria
  • renal failure
  • renal insufficiency
  • abnormality of the renal tubule
  • conjunctivitis
  • myopia
  • photophobia
  • hypertension
  • abnormality of the myocardium
  • abnormality of the pericardium
  • thrombocytopenia
  • tubulointerstitial abnormality
  • leukocytosis
  • abdominal pain
  • migraine
  • respiratory insufficiency
  • hemoptysis
  • pulmonary infiltrates
  • intracranial hemorrhage
  • pleural effusion
  • gastrointestinal hemorrhage
  • hypotension
  • arthralgia
  • elevated hepatic transaminases
  • hypoproteinemia
  • myalgia
  • arrhythmia
  • subconjunctival hemorrhage
  • fatigue
  • oliguria
  • amaurosis fugax
  • atelectasis

HPO human phenotypes related to Hemorrhagic Fever with Renal Syndrome:

(show all 28)
id Description Frequency HPO Source Accession
1 abnormality of temperature regulation hallmark (90%) HP:0004370
2 renal insufficiency typical (50%) HP:0000083
3 abnormality of the renal tubule typical (50%) HP:0000091
4 proteinuria typical (50%) HP:0000093
5 conjunctivitis typical (50%) HP:0000509
6 photophobia typical (50%) HP:0000613
7 thrombocytopenia typical (50%) HP:0001873
8 leukocytosis typical (50%) HP:0001974
9 abdominal pain typical (50%) HP:0002027
10 migraine typical (50%) HP:0002076
11 respiratory insufficiency typical (50%) HP:0002093
12 abnormality of the pleura typical (50%) HP:0002103
13 pulmonary infiltrates typical (50%) HP:0002113
14 arthralgia typical (50%) HP:0002829
15 elevated hepatic transaminases typical (50%) HP:0002910
16 hypoproteinemia typical (50%) HP:0003075
17 myalgia typical (50%) HP:0003326
18 atelectasis typical (50%) HP:0100750
19 myopia occasional (7.5%) HP:0000545
20 hypertension occasional (7.5%) HP:0000822
21 abnormality of the myocardium occasional (7.5%) HP:0001637
22 abnormality of the pericardium occasional (7.5%) HP:0001697
23 hemoptysis occasional (7.5%) HP:0002105
24 intracranial hemorrhage occasional (7.5%) HP:0002170
25 gastrointestinal hemorrhage occasional (7.5%) HP:0002239
26 hypotension occasional (7.5%) HP:0002615
27 arrhythmia occasional (7.5%) HP:0011675
28 amaurosis fugax occasional (7.5%) HP:0100576

Drugs & Therapeutics for Hemorrhagic Fever with Renal Syndrome

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Drugs for Hemorrhagic Fever with Renal Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
EpinephrinePhase 2, Phase 188651-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr.
Epipen Jr. Auto-Injector
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
Esphygmogenina
Exadrin
 
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
2
RibavirinPhase 296836791-04-537542
Synonyms:
1-.beta.-D-Ribofuranosyl-1,2,4-triazolo-3-carboxamide
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,4-triazole-3-carboxamide
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,4-triazole-3-carboxamide
1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide
1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide
1-beta-D-ribofuranosyl-1-H-1,2,4-triazole-3-carboxamide
36791-04-5
437710-49-1
66510-90-5
AA-504/07617051
AB00430481
AC1L1XXZ
AC1Q1IDC
AC1Q4ZGS
AKOS001715163
BB_NC-0567
BPBio1_001195
BRN 0892462
BSPBio_001085
BSPBio_003352
C-Virin
CHEMBL1643
CID37542
Copegus
Copegus (TN)
Cotronak
D00423
DB00811
DRG-0028
DivK1c_000782
Drug: Ribavirin
EU-0101063
FT-0082885
HMS2090L15
HMS2094O09
HMS502H04
HSDB 6513
ICN-1229
IDI1_000782
KBio1_000782
KBio2_002328
KBio2_004896
KBio2_007464
KBio3_002854
KBioGR_001804
KBioSS_002331
KS-1104
LS-1241
Lopac0_001063
MLS000028486
MLS002222317
MolPort-002-507-104
MolPort-002-885-856
NCGC00090726-01
NCGC00090726-03
NCGC00090726-04
NCGC00090726-05
NCGC00090726-06
NCGC00090726-07
NINDS_000782
NSC 163039
 
NSC163039
Prestwick3_000993
R 9644
R-964
R9644_SIGMA
RBV
RG-964
RIBAV
RTC
RTCA
RTP
Ravanex
Rebetol
Rebetol (TN)
Rebetron
Rebretron
Ribacine
Ribamide
Ribamidil
Ribamidyl
Ribasphere
Ribasphere (TN)
Ribav
Ribavirin
Ribavirin (JAN/USP/INN)
Ribavirin Capsules
Ribavirin Triphosphate
Ribavirin [USAN:INN]
Ribavirin-TP
Ribavirina
Ribavirina [INN-Spanish]
Ribavirine
Ribavirine [INN-French]
Ribavirinum
Ribavirinum [INN-Latin]
Ribovirin
Ro 20-9963/000
Ro-20-9963
S2504_Selleck
SCH 18908
SMP1_000261
SMR000058315
SPECTRUM1503938
SR-01000076112-3
Spectrum3_001876
Spectrum4_001252
Spectrum5_002075
Spectrum_001826
Tribavirin
UNII-49717AWG6K
Varazid
Vilona
Viramid
Viramide
Virazid
Virazide
Virazole
Virazole (Ribavirin) Inhalation Solution
Virazole (TN)
Virazole 5'-triphosphate
ZINC01035331
ribavirin

Interventional clinical trials:

idNameStatusNCT IDPhase
1Study to Evalutate Long-term Immunity of Hantavax in High Risk Population of HFRSCompletedNCT02360514Phase 3
2Phase 2a Immunogenicity Study of Hantaan/Puumala Virus DNA Vaccine for Prevention of Hemorrhagic FeverRecruitingNCT02116205Phase 2
3Ribavirin for Hemorrhagic Fever With Renal SyndromeEnrolling by invitationNCT00623168Phase 2
4Ribavirin for Hemorrhagic Fever With Renal Syndrome in GermanyEnrolling by invitationNCT00868946Phase 2
5Palifermin in Preventing Oral Mucositis Caused by Chemotherapy and/or Radiation Therapy in Young Patients Undergoing Stem Cell TransplantWithdrawnNCT00728585Phase 2
6Study to Evaluate the Safety, Tolerability, and Immunogenicity of Hantaan and Puumala Virus DNA VaccinesCompletedNCT01502345Phase 1
7Diagnostic of Puumala Virus Infection in FranceRecruitingNCT02455375
8Cohort of Patients Infected by an ArbovirusRecruitingNCT01099852
9Phenotyping IBS: Perceptions and Modulations of Visceral SensationsRecruitingNCT02693730

Search NIH Clinical Center for Hemorrhagic Fever with Renal Syndrome


Cochrane evidence based reviews: hemorrhagic fever with renal syndrome

Genetic Tests for Hemorrhagic Fever with Renal Syndrome

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Anatomical Context for Hemorrhagic Fever with Renal Syndrome

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MalaCards organs/tissues related to Hemorrhagic Fever with Renal Syndrome:

34
Kidney, T cells, Testes, Skin, B cells, Endothelial, Neutrophil

FMA organs/tissues related to Hemorrhagic Fever with Renal Syndrome:

17
Kidney

Animal Models for Hemorrhagic Fever with Renal Syndrome or affiliated genes

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MGI Mouse Phenotypes related to Hemorrhagic Fever with Renal Syndrome:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053977.5B2M, CD40LG, CD55, IL6, SEMA4D, SERPINC1

Publications for Hemorrhagic Fever with Renal Syndrome

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Articles related to Hemorrhagic Fever with Renal Syndrome:

(show top 50)    (show all 361)
idTitleAuthorsYear
1
History of incomplete vaccination may associate with occurrence of hemorrhagic fever with renal syndrome with relieved clinical symptoms. (26636561)
2016
2
Acalculous cholecystitis associated with hemorrhagic fever with renal syndrome: a case report. (25982259)
2015
3
Using autoregressive integrated moving average model to predict the incidence of hemorrhagic fever with renal syndrome in Zibo, China, 2004-2014. (26370428)
2015
4
Comparison of Two Hybrid Models for Forecasting the Incidence of Hemorrhagic Fever with Renal Syndrome in Jiangsu Province, China. (26270814)
2015
5
Increased risk for lymphoma following hemorrhagic fever with renal syndrome. (24965350)
2014
6
Analysis of an outbreak of hemorrhagic fever with renal syndrome in college students in Xi'an, China. (24481251)
2014
7
Increasing incidence of hemorrhagic fever with renal syndrome could be associated with livestock husbandry in Changchun, northeastern China. (24894341)
2014
8
Hemorrhagic fever with renal syndrome and Crimean-Congo hemorrhagic fever as causes of acute undifferentiated febrile illness in Bulgaria. (23421884)
2013
9
A case of ruptured renal cortical arteriovenous malformation of the right testicular vein in hemorrhagic fever with renal syndrome. (23682233)
2013
10
Serum TNF-I+, sTNFR1, IL-6, IL-8 and IL-10 levels in hemorrhagic fever with renal syndrome. (23603136)
2013
11
Correction: Investigating the Effects of Food Available and Climatic Variables on the Animal Host Density of Hemorrhagic Fever with Renal Syndrome in Changsha, China. (24058426)
2013
12
Hantaan virus RNA load in patients having hemorrhagic fever with renal syndrome: correlation with disease severity. (22869912)
2013
13
Investigating the effects of food available and climatic variables on the animal host density of hemorrhagic Fever with renal syndrome in changsha, china. (23637849)
2013
14
Isolation and characterization of hantaviruses in Far East Russia and etiology of hemorrhagic fever with renal syndrome in the region. (22403334)
2012
15
Increased serum fibronectin levels in patients with hemorrhagic fever with renal syndrome. (19701604)
2010
16
Collective immunity of the population from endemic zones of hemorrhagic fever with renal syndrome in Kosovo. (20088164)
2009
17
Hemorrhagic fever with renal syndrome in 4 US soldiers, South Korea, 2005. (19891878)
2009
18
Hemorrhagic fever with renal syndrome caused by 2 lineages of Dobrava hantavirus, Russia. (18394280)
2008
19
Hemorrhagic fever with renal syndrome complicated with pregnancy: a case report. (16913449)
2006
20
Hemorrhagic fever with renal syndrome in the Pomurje region of Slovenia--an 18-year survey. (16053195)
2005
21
Rehabilitation therapy of convalescents after hemorrhagic fever with renal syndrome in outpatient clinic]. (15108430)
2004
22
Hemorrhagic fever with renal syndrome. (15540521)
2004
23
Serological analysis of hemorrhagic fever with renal syndrome (HFRS) patients in Far Eastern Russia and identification of the causative hantavirus genotype. (12898330)
2003
24
A case of torsade de pointes associated with hypopituitarism due to hemorrhagic fever with renal syndrome. (11410700)
2001
25
Epidemiological progresses of hemorrhagic fever with renal syndrome in China. (11593522)
1999
26
Puumala and Dobrava viruses cause hemorrhagic fever with renal syndrome in Bosnia-Herzegovina: evidence of highly cross-neutralizing antibody responses in early patient sera. (9298732)
1997
27
Pathogenetic and clinical aspects of the renal involvement in hemorrhagic fever with renal syndrome. (9044447)
1997
28
Direct genetic detection of Dobrava virus in Greek and Albanian patients with hemorrhagic fever with renal syndrome. (8699076)
1996
29
Hemorrhagic fever with renal syndrome: a study of sequelae following nephropathia epidemica. (7944947)
1994
30
Hemorrhagic fever with renal syndrome in California. (7817560)
1994
31
Epidemiologic surveillance on the hemorrhagic fever with renal syndrome in China. (7908258)
1993
32
Hypertension after hemorrhagic fever with renal syndrome. (1356239)
1992
33
Comparison of European isolates of viruses causing hemorrhagic fever with renal syndrome by a neutralization test. (1684888)
1991
34
Localization and changes of hemorrhagic fever with renal syndrome virus in lymphocyte subpopulation. (1680612)
1991
35
Interruption study of viremia of patients with hemorrhagic fever with renal syndrome in the febrile phase. (1678691)
1991
36
Nephropathia epidemica: mild variant of hemorrhagic fever with renal syndrome. (1685202)
1991
37
Two cases of hyperimmunoglobulinemia E in patients with hemorrhagic fever with renal syndrome. (1679249)
1991
38
Hemorrhagic fever with renal syndrome. (2647265)
1989
39
What is new and where are the problems in research on hemorrhagic fever with renal syndrome? (2573193)
1989
40
Hemorrhagic fever with renal syndrome. (2573914)
1989
41
Cats--source of protection or infection? A case-control study of hemorrhagic fever with renal syndrome. (2889355)
1987
42
Hemorrhagic fever with renal syndrome: treatment with recombinant alpha interferon. (2881968)
1987
43
Isolation of a hantavirus from a severely ill patient with hemorrhagic fever with renal syndrome in Greece. (2890690)
1987
44
Characterization of glycoproteins of viruses causing hemorrhagic fever with renal syndrome (HFRS) using monoclonal antibodies. (2422813)
1986
45
A preliminary report on hemorrhagic fever with renal syndrome in China. (6137329)
1983
46
Hemorrhagic fever with renal syndrome (HFRS). (6134332)
1982
47
Hemorrhagic fever with renal syndrome in Finland: ecology and virology of nephropathia epidemica. (6134333)
1982
48
Hantaan virus is related to hemorrhagic fever with renal syndrome in Norway. (6125745)
1982
49
Seroepidemiologic study of epidemic hemorrhagic fever with renal syndrome in China. (6114815)
1981
50
GEOGRAPHICAL DISTRIBUTION OF HEMORRHAGIC FEVER WITH RENAL SYNDROME. (14196952)
1964

Variations for Hemorrhagic Fever with Renal Syndrome

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Expression for genes affiliated with Hemorrhagic Fever with Renal Syndrome

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Search GEO for disease gene expression data for Hemorrhagic Fever with Renal Syndrome.

Pathways for genes affiliated with Hemorrhagic Fever with Renal Syndrome

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Pathways related to Hemorrhagic Fever with Renal Syndrome according to GeneCards Suite gene sharing:

(show all 18)
idSuper pathwaysScoreTop Affiliating Genes
19.7CD40LG, IL6, TNF
29.7CD40LG, IL6, TNF
39.5IL6, TNF, VTN
49.5HLA-DRB1, IL6, TNF
59.4CD163, IL6, TNF
69.4CD163, IL6, TNF
79.4CD40LG, HLA-DRB1, HLA-DRB5
8
Show member pathways
9.2B2M, CD40LG, HLA-DRB5, TNF
9
Show member pathways
9.1CD40LG, HLA-DRB1, HLA-DRB5, TNF
10
Show member pathways
9.1CD40LG, HLA-DRB1, HLA-DRB5, TNF
119.0HLA-DRB1, HLA-DRB5, IL6, TNF
129.0HLA-DRB1, HLA-DRB5, IL6, TNF
139.0HLA-DRB1, HLA-DRB5, IL6, TNF
14
Show member pathways
9.0CD55, SERPINC1, VTN
15
Show member pathways
8.8ALB, CRP, IL6, TNF
168.5CD55, HLA-DRB1, HLA-DRB5, IL6, TNF
17
Show member pathways
7.9B2M, CD40LG, CD55, HLA-DRB1, HLA-DRB5, IL6
18
Show member pathways
7.3B2M, CD40LG, CD55, CRP, HLA-DRB1, HLA-DRB5

GO Terms for genes affiliated with Hemorrhagic Fever with Renal Syndrome

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Cellular components related to Hemorrhagic Fever with Renal Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1MHC class II protein complexGO:004261310.3HLA-DRB1, HLA-DRB5
2ER to Golgi transport vesicle membraneGO:001250710.0B2M, HLA-DRB1, HLA-DRB5
3external side of plasma membraneGO:00098979.9B2M, CD40LG, IL6, TNF
4endocytic vesicle membraneGO:00306669.6CD163, HLA-DRB1, HLA-DRB5
5blood microparticleGO:00725629.0ALB, SERPINC1, VTN
6extracellular spaceGO:00056157.1ALB, B2M, CD40LG, CRP, IL6, SEMA4D
7plasma membraneGO:00058866.8B2M, CD163, CD40LG, CD55, HLA-DRB1, HLA-DRB5
8extracellular exosomeGO:00700626.7ALB, B2M, CD55, CRP, HLA-DRB1, HLA-DRB5
9extracellular regionGO:00055766.6ALB, B2M, CD163, CD55, CRP, IL6

Biological processes related to Hemorrhagic Fever with Renal Syndrome according to GeneCards Suite gene sharing:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of chemokine productionGO:003272210.5IL6, TNF
2epithelial cell proliferation involved in salivary gland morphogenesisGO:006066410.5IL6, TNF
3negative regulation of alkaline phosphatase activityGO:001069310.5SEMA4D, TNF
4regulation of immunoglobulin secretionGO:005102310.5CD40LG, TNF
5positive regulation of receptor-mediated endocytosisGO:004826010.3B2M, VTN
6negative regulation of lipid storageGO:001088810.0CRP, IL6, TNF
7cellular response to lipopolysaccharideGO:00712229.9B2M, IL6, TNF
8acute-phase responseGO:00069539.8CD163, CRP, IL6
9interferon-gamma-mediated signaling pathwayGO:00603339.8B2M, HLA-DRB1, HLA-DRB5
10positive regulation of peptidyl-tyrosine phosphorylationGO:00507319.8IL6, SEMA4D, VTN
11positive regulation of NF-kappaB transcription factor activityGO:00510929.7CD40LG, IL6, TNF
12T cell costimulationGO:00312959.4CD40LG, HLA-DRB1, HLA-DRB5
13inflammatory responseGO:00069549.3CD40LG, CRP, IL6, TNF
14defense response to Gram-positive bacteriumGO:00508309.0B2M, CRP, IL6, TNF

Sources for Hemorrhagic Fever with Renal Syndrome

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet