MCID: HMS001
MIFTS: 45

Hemosiderosis malady

Categories: Rare diseases, Metabolic diseases

Aliases & Classifications for Hemosiderosis

About this section

Aliases & Descriptions for Hemosiderosis:

Name: Hemosiderosis 11 48 50 39 13 68
 
Haemosiderosis 11

Classifications:



External Ids:

Disease Ontology11 DOID:12119
MeSH39 D006486
SNOMED-CT62 190849009, 39011001
NCIt45 C82892

Summaries for Hemosiderosis

About this section
Disease Ontology:11 An iron metabolism disease that has material basis in an accumulation of hemosiderin, an iron-storage complex, resulting in iron overload.

MalaCards based summary: Hemosiderosis, also known as haemosiderosis, is related to lupus erythematosus and thalassemia minor, and has symptoms including transfusion-related circulatory overload and transfusion-associated dyspnoea. An important gene associated with Hemosiderosis is CP (Ceruloplasmin), and among its related pathways are Metal ion SLC transporters and Iron metabolism in placenta. The drug cyclophosphamide has been mentioned in the context of this disorder. Affiliated tissues include liver, lung and heart, and related mouse phenotypes are hematopoietic system and homeostasis/metabolism.

Wikipedia:71 Hemosiderosis (AmE) or haemosiderosis (BrE) is a form of iron overload disorder resulting in the... more...

Related Diseases for Hemosiderosis

About this section

Diseases related to Hemosiderosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 144)
idRelated DiseaseScoreTop Affiliating Genes
1lupus erythematosus30.0CP, GPT
2thalassemia minor29.3HBB, HFE
3atransferrinemia28.5CP, HFE, SLC11A2, TF
4porphyria cutanea tarda28.4HFE, TF
5sickle cell anemia28.0EPO, HBB, HFE, TF
6pulmonary hemosiderosis12.2
7secondary pulmonary hemosiderosis11.9
8gracile syndrome10.9
9cerebellar ataxia10.9
10aceruloplasminemia10.9
11superficial siderosis10.9
12multiple system atrophy with orthostatic hypotension10.4CAT, CP
13rectal disease10.3CP, TF
14ivic syndrome10.3CP, TF
15scn8a encephalopathy10.3CP, TF
16alveolar periostitis10.2GPT, TF
17hereditary multiple osteochondromas10.2HFE, SLC11A2
18diphtheria10.2CP, TF
19hemochromatosis10.2
20hepatitis10.2
21nondystrophic myotonia10.1GPT, HFE
22breast epithelioid hemangioma10.1CAT, TF
23dermatoosteolysis, kirghizian type10.1HFE, TF
24alcoholic liver cirrhosis10.1GPT, TF
25celiac disease10.0
26thbd-related atypical hemolytic-uremic syndrome10.0HBB, HFE
27harp syndrome10.0HFE, TF
28urinary bladder posterior wall cancer10.0CP, GPT, TF
29thalassemia10.0
30endometrial adenocarcinoma10.0HBB, HFE
31parkinson disease, late-onset10.0CAT, CP, SLC11A2
32diplegia of upper limb10.0CAT, CP
33deficiency anemia9.9
34iron deficiency anemia9.9
35glomerulonephritis9.9
36cerebritis9.9
37postpartum depression9.9EPO, TF
38malignant visceral pleura tumor9.9EPO, TF
39timothy syndrome type 19.9EPO, HBB
40splenic infarction9.9EPO, HBB
41skin sarcoidosis9.8EPO, TF
42rift valley fever9.8HFE, TF
43heart disease9.8
44spastic paraplegia 3a9.8EPO, HBB
45hemolytic anemia9.8
46paroxysmal nocturnal hemoglobinuria9.8
47hemoglobinuria9.8
48thalassemia major9.8
49basilar artery insufficiency9.8EPO, HFE
50pyruvate kinase deficiency9.7EPO, HFE

Graphical network of the top 20 diseases related to Hemosiderosis:



Diseases related to hemosiderosis

Symptoms & Phenotypes for Hemosiderosis

About this section

UMLS symptoms related to Hemosiderosis:


transfusion-related circulatory overload, transfusion-associated dyspnoea

MGI Mouse Phenotypes related to Hemosiderosis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053978.2CP, EPO, GPT, HFE, MIF, SLC11A2
2MP:00053767.2CAT, CP, EPO, HFE, MIF, SLC11A2

Drugs & Therapeutics for Hemosiderosis

About this section

Drugs for Hemosiderosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 24)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
DeferiproneapprovedPhase 4, Phase 2, Phase 35730652-11-02972
Synonyms:
1,2-Dimethyl-3-hydroxypyrid-4-one
3-Hydroxy-1,2-dimethyl-4(1H)-pyridone
APO-066
CP-20
DN-180-01-AF
Deferipron
 
Deferiprona
Deferiproni
Deferipronum
Deferypron
Dimethylhydroxypyridone
Défériprone
Ferriprox
PL-1
2
Deferoxamineapproved, investigationalPhase 4, Phase 2, Phase 34570-51-92973
Synonyms:
DF B
DFO
DFOA
DFOM
Deferoxamide B
Deferoxamin
Deferoxamina
 
Deferoxamine B
Deferoxaminum
Deferrioxamine
Deferrioxamine B
Deferrioxamine b
Desferrioxamine
Desferrioxamine B
Déferoxamine
N-Benzoylferrioxamine B
3
IronapprovedPhase 4, Phase 2, Phase 311237439-89-623925
Synonyms:
02583_FLUKA
12310_ALDRICH
12310_RIEDEL
129048-51-7
14067-02-8
161135-39-3
190454-13-8
195161-83-2
199281-22-6
209309_ALDRICH
209309_SIAL
255637_ALDRICH
266213_ALDRICH
266256_ALDRICH
267945_ALDRICH
267953_ALDRICH
26Fe
338141_ALDRICH
356808_ALDRICH
356824_ALDRICH
356832_ALDRICH
39344-71-3
3ZhP
413054_ALDRICH
443783-52-6
44890_ALDRICH
44890_FLUKA
675141-17-0
70884-35-4
73135-38-3
7439-89-6
8011-79-8
8053-60-9
AC1L2N38
ATW 230
ATW 432
Ancor B
Ancor en 80/150
Armco iron
Atomel 28
Atomel 300M200
Atomel 500M
Atomel 95
Atomiron 44MR
Atomiron 5M
Atomiron AFP 25
Atomiron AFP 5
C00023
C3518_SIAL
C3518_SIGMA
CCRIS 1580
CHEBI:18248
CID23925
Carbonyl iron
Copy Powder CS 105-175
D007501
DB01592
DSP 1000
DSP 128B
DSP 135
DSP 135C
DSP 138
Diseases (animal), iron overload
Diseases, iron overload
EF 1000
EF 250
EFV 200/300
EFV 250
EFV 250/400
EINECS 231-096-4
 
Ed-In-Sol
Eisen
Electrolytic iron
F 60 (metal)
FE
FT 3 (element)
Fe
Fe-40
Fe1+
Feronate
Ferretts
Ferro-Caps
Ferro-Time
Ferrousal
Ferrovac E
Ferrum
Ferrum metallicum
GS 6
HF 2 (element)
HL (iron)
HQ (metal)
HS (iron)
HS 4849
HSDB 604
Hemocyte
Hierro
Hoeganaes ATW 230
Hoeganaes EH
IRMM524A_FLUKA
IRMM524B_FLUKA
IRON
Iron (Fe)
Iron (Fe1+)
Iron ion (Fe+)
Iron ion(1+)
Iron monocation
Iron powder
Iron standard for AAS
Iron(1+)
Iron(1+) ion
Iron(III) nitrate solution
Iron, carbonyl
Iron, electrolytic
Iron, elemental
Iron, ion (Fe1+)
Iron, ion (Fe1+) (8CI,9CI)
Iron, reduced
LOHA
LS-3196
MolPort-003-925-001
NC 100
PZh-1M3
PZh-2
PZh1M1
PZh2M
PZh2M1
PZh2M2
PZh3
PZh3M
PZh4M
PZhO
Reduced iron
Remko
SUY-B 2
Siderol
UNII-E1UOL152H7
Vitedyn-Slo
Yieronia
fer
ferrous iron
hierro
4
Deferasiroxapproved, investigationalPhase 4, Phase 2, Phase 389201530-41-85493381
Synonyms:
Deferasiroxum
Deferasiroxum [inn-latin]
 
Exjade
ICL 670
ICL 670a
deferasirox
5
MetforminapprovedPhase 41746657-24-914219, 4091
Synonyms:
1,1-Dimethyl biguanide
1,1-Dimethylbiguanide
3-(diaminomethylidene)-1,1-dimethylguanidine
657-24-9
AC1L1HE4
AKOS000121065
Apo-Metformin
BIDD:GT0697
BPBio1_000009
BRD-K79602928-003-04-1
BSPBio_000007
BSPBio_002314
C07151
C4H11N5
CAS-1115-70-4
CCRIS 9321
CHEBI:6801
CHEMBL1431
CID4091
D04966
DB00331
DMGG
Diabetosan
Diabex
Dimethylbiguanid
Dimethylbiguanide
Dimethylbiguanidine
Dimethyldiguanide
Dimethylguanylguanidine
EINECS 211-517-8
Fluamine
Flumamine
Fortamet
Gen-Metformin
Glifage
Gliguanid
Glucophage
Glucophage XR
Glumetza
Glycon
HMS2089D19
HSCI1_000295
Haurymelin
Haurymellin
Islotin
KBio2_002310
KBio2_004878
KBio2_007446
KBio3_002790
KBioGR_002310
 
KBioSS_002312
LA-6023
LS-43899
Melbin
Metformin
Metformin (USAN/INN)
Metformin HCL
Metformin [USAN:INN:BAN]
Metformina
Metformina [DCIT]
Metformina [Spanish]
Metformine
Metformine [INN-French]
Metformine pamoate
Metforminum
Metforminum [INN-Latin]
Metiguanide
MolPort-002-929-560
MolPort-004-288-389
MolPort-005-767-418
Mylan-Metformin
N,N-Dimethylbiguanide
N,N-Dimethyldiguanide
N,N-Dimethylimidodicarbonimidic diamide
N,N-dimethylimidodicarbonimidic diamide
N1,N1-Dimethylbiguanide
NCGC00016564-01
NCGC00016564-02
NCGC00016564-03
NNDG
Novo-Metformin
Nu-Metformin
PMS-Metformin
Prestwick0_000004
Prestwick1_000004
Prestwick2_000004
Prestwick3_000004
Ran-Metformin
Ratio-Metformin
Riomet
S2483_Selleck
SPBio_001928
STK011633
Sandoz Metformin
Siofor
T5895664
Teva-Metformin
UNII-9100L32L2N
ZINC12859773
cMAP_000016
metformin
metformin hydrochloride
6Chelating AgentsPhase 4, Phase 2, Phase 31365
7Liver ExtractsPhase 4, Phase 2, Phase 33868
8MicronutrientsPhase 4, Phase 2, Phase 35802
9Iron Chelating AgentsPhase 4, Phase 2, Phase 3222
10Trace ElementsPhase 4, Phase 2, Phase 35802
11Hypoglycemic AgentsPhase 45733
12
Ergocalciferolapproved, nutraceuticalPhase 2123250-14-65280793
Synonyms:
'Ergosterol irradiated'
(+)-Vitamin D2
(3-beta,5Z,7E,22E)-9,10-Secoergosta-5,7,10,(19),22-tetraen-3-ol
(3S,5Z,7E,14xi,17alpha,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol
(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(3S,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol
(3beta,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(3beta,5Z,7e,22e)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
(5E,7E,22E)-9,10-Secoergosta-5,7,10,22-tetraen-3-ol
(5Z,7E,22E)-(3S)-9,10-seco-5,7,10(19),22-ergostatetraen-3-ol
(5Z,7E,22E)-(3S)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol
(5Z,7e,22e)-(3S)-9,10-Seco-5,7,10(19),22-ergostatetraen-3-ol
(5Z,7e,22e)-(3S)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
22-Tetraen 3beta 9,10,Secoergosta-5,7,10(19)-ol
31316-19-5
4-Methylene-3-[2-[tetrahydro-7a-methyl-1-(1,4,5-trimethyl-2-hexenyl)-4(3aH)-indanylidene]ethylidene]-Cyclohexanol
47768_SUPELCO
50-14-6
7489-18-1
7E677DC1-E1C4-4FC5-8F4A-BCE1857F7E87
8017-28-5
9,10,Secoergosta-5,7,10(19),22-tetraen 3.beta.-ol
9,10-Seco(5Z,7E,22E)-5,7,10(19),22-ergostatetraen-3-ol
9,10-Secoergosta-5,7,10(19),22-tetraen-3-beta-ol
9,10-Secoergosta-5,7,10(19),22-tetraen-3b-ol
95220_FLUKA
95220_SIGMA
AC-1355
AC1L1FIE
AC1NQXLH
AC1NS4DE
AC1NS9GI
AC1NSSVD
AC1NWAM3
AC1O5EDK
AC1O6WAM
ACon1_002187
Activated ergosterol
BPBio1_000418
BSPBio_000380
BSPBio_001974
Buco-D
C05441
C28H44O
CALCIFEROL IN A GELATIN MATRIX
CALCIFEROL, U.S.P.
CHEBI:28934
CHEMBL1536
CID11003810
CID3249
CID5280793
CID5315257
CID5353610
CID5356615
CID5702050
CID6432478
CID6536972
Calciferol
Calciferol (TN)
Calciferol (vitamin D2)
Calciferolum
Calciferon 2
Condacaps
Condocaps
Condol
Crtron
Crystallina
D-Arthin
D-Tracetten
D00187
DB00153
Daral
Davitamon D
Davitin
De-rat concentrate
Decaps
Dee-Osterol
Dee-Ron
Dee-Ronal
Dee-Roual
Deltalin
Deratol
Detalup
Diactol
Divit urto
Doral
Drisdol
Drisdol (TN)
E5750_SIGMA
EINECS 200-014-9
Ercalciol
Ergocalciferol
Ergocalciferol (D2)
Ergocalciferol (JP15/USP)
Ergocalciferol [INN:BAN:JAN]
Ergocalciferol oil
Ergocalciferol: Vitamin D
 
Ergocalciferolo
Ergocalciferolo [DCIT]
Ergocalciferols
Ergocalciferolum
Ergocalciferolum [INN-Latin]
Ergorone
Ergosterol activated
Ergosterol irradiated
Ergosterol, irradiated
Ertron
Fortodyl
Geltabs
Geltabs Vitamin D
HMS1920K20
HMS2091B19
HMS502I07
HSDB 819
Haliver
Hi-Deratol
Hyperkil
I05-0022
IDI1_000805
Infron
Irradiated ergosta-5,7,22-trien-3-beta-ol
Irradiated ergosta-5,7,22-trien-3.beta.-ol
Irradiated ergosta-5,7,22-trien-3beta-ol
Irradiated ergosterol
LMST03010001
LMST03010014
LS-3228
MEGxm0_000466
MLS001332467
MLS001332468
Metadee
Mina D2
MolPort-001-740-057
MolPort-001-793-930
MolPort-002-526-645
MolPort-003-666-178
MolPort-006-822-629
Mulsiferol
Mykostin
NCGC00142497-01
NCGC00179579-01
NCGC00179579-02
NSC 62792
NSC62792
Novovitamin-D
Oleovitamin D
Oleovitamin D, Synthetic
Oleovitamin D2
Osteil
Ostelin
Prestwick3_000420
Prestwick_554
Radiostol
Radstein
Radsterin
Rodine C
Rodinec
SMR000857106
SPECTRUM1500276
ST057150
STOCK1N-53397
Shock-ferol
Shock-ferol sterogyl
Sorex C.R
Sorex C.R.
Spectrum5_000666
Sterogyl
Synthetic Vitamin D
UNII-VS041H42XC
Uvesterol D
Uvesterol-D
VITAMIN D2
VITAMIN D2 WATER DISPERSABLE U.S.P.
VITAMIN_D2
Vigantol
Vio D
Vio-D
Viostdrol
Viosterol
Viosterol in Oil
Vitamin D2
Vitamin- D2
Vitamin-?D2
Vitamina D2
Vitavel-D
WLN: L56 FYTJ A1 BY1&1U1Y1&Y1&1 FU2U- BL6YYTJ AU1 DQ
ZINC04474571
ZINC04629876
beta-Ol
bmse000510
component of Geltabs Vitamin D
delta-Arthin
delta-Tracetten
ergocalciferol
vitamin d-2
13
Cholecalciferolapproved, nutraceuticalPhase 285167-97-06221, 10883523, 5280795
Synonyms:
()-Vitamin D3
(+)-Vitamin D3
(+)-vitamin D3
(1S,3Z)-3-[(2e)-2-[(1R,3AR,7as)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-ol
(3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(3beta,5Z,7e)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
(3beta,Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
(5E,7E)-9,10-Secocholesta-5,7,10-trien-3-ol
(5Z,7E)-(3S)-9,10-seco-5,7,10(19)-cholestatrien-3-ol
(5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol
(5Z,7e)-(3S)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
1406-16-2
25(OH)D
3-beta,Z,7E-9,10-Secocholestr-5,7,10(19)-trien-3-ol
47763_SUPELCO
57651-82-8
67-97-0
7-Dehydrocholesterol activated
7-Dehydrocholesterol, Activated
7-Dehydrocholesterol, irradiated
7-Dehydrocholestrol, activated
8024-19-9
8050-67-7
89193_FLUKA
9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3-ol
9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3beta-ol
9,10-Secocholesta-5(Z),7(E),10(19)-trien-3(.beta.)-ol
9,10-Secocholesta-5,7,10(19)-trien-3-beta-ol
9,10-Secocholesta-5,7,10(19)-trien-3-ol
9,10-Secocholesta-5,7,10-trien-3-ol
AB1002422
AC-11697
AC1L1ECK
AC1L1M23
AC1LU7IZ
AC1NQXLN
AC1NR2UO
AC1NR2UR
AC1NR2UU
AC1NS4AJ
AC1NSHJX
AC1O5EOF
AC1O7GAV
AC1O7GQ3
AC1O8FEU
AC1O8PWJ
AC1OF2GI
AC1OF2GL
AC1OIEW5
AC1OIEWB
ACon1_001997
Activated 7-dehydrocholesterol
Arachitol
BPBio1_000460
BSPBio_000418
BSPBio_002408
Bio-0845
C05443
C1357_SIAL
C27H44O
C9756_SIGMA
C9774_SIAL
CAS-67-97-0
CC
CCRIS 5813
CCRIS 6286
CHEBI:283119
CHEBI:28940
CHEMBL1042
CHEMBL432780
CID10000117
CID10045875
CID10340013
CID10883523
CID10894379
CID11014566
CID11025493
CID11058152
CID11463269
CID1548921
CID2735
CID5280795
CID5283710
CID5283711
CID5283712
CID5353527
CID5363362
CID6221
CID6432644
CID6604201
CID6604662
CID6708595
CID6713938
CID6992015
CID6992016
CID7067439
CID7067440
CID7251172
CID7251174
CID9821465
Calciol
Cholecalciferol
Cholecalciferol (D3)
Cholecalciferol (JP15/USP)
Cholecalciferol D3
Cholecalciferol [USAN:BAN:JAN]
Cholecalciferol, D3
Cholecalciferolum
 
Colecalciferol
Colecalciferol (INN)
Colecalciferolo
Colecalciferolo [DCIT]
Colecalciferolum
Colecalciferolum [INN-Latin]
Colecalcipherol
D00188
D3-Vicotrat
D3-Vigantol
DB00169
Delsterol
Delta-D
Delta-D (TN)
Deparal
Devaron
DivK1c_006276
Duphafral D3 1000
EINECS 200-673-2
EINECS 215-797-2
EPA Pesticide Chemical Code 202901
Ebivit
FeraCol
Granuvit D3
HMS1569E20
HMS2092M12
HSDB 820
I05-0041
Irradiated 7-dehydrocholesterol
KBio1_001220
KBio2_001643
KBio2_004211
KBio2_006779
KBio3_001628
KBioGR_001602
KBioSS_001643
LMST03020001
LMST03020219
LMST03020220
LMST03020221
LS-1570
LS-825
LT00244775
MEGxm0_000458
Micro-dee
MolPort-001-740-051
MolPort-001-785-972
MolPort-003-666-021
MolPort-004-946-964
NCGC00016301-01
NCGC00017328-01
NCGC00091072-01
NCGC00142511-01
NCGC00159331-02
NCGC00159331-04
NCGC00178668-01
NCGC00179565-01
NCGC00179565-02
NEO Dohyfral D3
NSC 375571
NSC-375571
NSC375571
Oleovitamin D3
Prestwick0_000429
Prestwick1_000429
Prestwick2_000429
Prestwick3_000429
Prestwick_63
Provitamine
Provitina
Quintox
Rampage
Ricketon
SMP1_000068
SPBio_001298
SPBio_002357
SR-05000001559
SR-05000001559-3
ST057172
SpecPlus_000180
Spectrum2_001369
Spectrum3_000764
Spectrum4_001201
Spectrum_001163
TNP00266
Trivitan
UNII-1C6V77QF41
UPCMLD-DP152
UPCMLD-DP152:001
VITAMIN D
VITAMIN D3 POWDER
VITAMIN_D3
Vi-De3
Vi-de-3-hydrosol
VidDe-3-hydrosol
Videkhol
Vigantol
Vigorsan
Vitamin D3
Vitamin D3 emulsifiable
Vitinc Dan-Dee-3
ZINC04474460
ZINC04492874
ZINC04492875
ZINC04492876
ZINC04492878
bmse000507
calciol
cholecalciferol
delta-D
vitamin d-3
14Epoetin alfaPhase 2645113427-24-0
15HematinicsPhase 21630
16vitamin dPhase 21653
17VitaminsPhase 25095
18ErgocalciferolsPhase 21232
19Bone Density Conservation AgentsPhase 23266
20Calcium, DietaryPhase 25525
21Vitamin D2NutraceuticalPhase 21232
22CalciferolNutraceuticalPhase 21334
23
Benzocaineapproved18921994-09-7, 94-09-72337
Synonyms:
(p-(Ethoxycarbonyl)phenylamine
06952_FLUKA
112909_ALDRICH
112909_SIAL
1333-08-0
23239-88-5
23239-88-5 (hydrochloride)
4 Aminobenzoic Acid Ethyl Ester
4-(Ethoxycarbonyl)aniline
4-(Ethoxycarbonyl)phenylamine
4-14-00-01129 (Beilstein Handbook Reference)
4-Aminobenzoate
4-Aminobenzoic acid
4-Aminobenzoic acid ethyl ester
4-Aminobenzoic acid, ethyl ester
4-Carbethoxyaniline
4-amino-benzoic acid ethyl ester
4-aminobenzoic acid ethyl ester
71123-91-6
94-09-7
94-09-7 (Parent)
A0271
AB00051923
AC1L1DGC
AC1Q341A
AC1Q64JE
AE-562/40377256
AI3-02081
AKOS000119763
AR-1H9065
Acetate, Benzocaine
Aethoform
Aethylium paraminobenzoicum
Amben ethyl ester
Americaine
Anaesthan-syngala
Anaesthesin
Anaesthesinum
Anaesthin
Anestezin
Anestezin [Russian]
Anesthesin
Anesthesine
Anesthone
BB_SC-0019
BPBio1_001017
BRD-K75466013-001-05-2
BRN 0638434
BSPBio_000923
BSPBio_001908
Baby Anbesol
Bensokain
Benzoak
Benzocaina
Benzocaina [INN-Spanish]
Benzocaine
Benzocaine (USP/INN)
Benzocaine Acetate
Benzocaine Formate
Benzocaine Hydrobromide
Benzocaine Hydrochloride
Benzocaine Methanesulfonate
Benzocaine [INN:BAN]
Benzocainum
Benzocainum [INN-Latin]
Benzoic acid, 4-amino-, ethyl ester
Benzoic acid, 4-amino-, ethyl ester, hydrochloride
Benzoic acid, amino-, ethyl ester
Benzoic acid, p-amino-, ethyl ester
C07527
CAS-94-09-7
CHEBI:116735
CHEMBL278172
CID2337
Caswell No. 430A
Chloraseptic
D001566
D00552
DB01086
Dermoplast
Diet Ayds
DivK1c_000932
E1501_SIGMA
EINECS 202-303-5
EPA Pesticide Chemical Code 097001
ETHYL-P-AMINOBENZOATE
Ethoform
Ethoforme
Ethyl 4-aminobenzoate
Ethyl 4-aminobenzoate hydrochloride
Ethyl 4-aminobenzoic acid
Ethyl Aminobenzoate
Ethyl PABA
 
Ethyl aminobenzoate
Ethyl aminobenzoate (JP15)
Ethyl aminobenzoate (VAN)
Ethyl aminobenzoic acid
Ethyl p-Aminobenzoate
Ethyl p-Aminophenylcarboxylate
Ethyl p-aminobenzenecarboxylate
Ethyl p-aminobenzoate
Ethyl p-aminobenzoic acid
Ethyl p-aminophenylcarboxylate
Ethylester kyseliny p-aminobenzoove
Ethylester kyseliny p-aminobenzoove [Czech]
Ethylis aminobenzoas
Formate, Benzocaine
HMS1570O05
HMS1920G09
HMS2091M11
HMS502O14
HSDB 7225
Hurricaine
Hydrobromide, Benzocaine
Hydrochloride, Benzocaine
I05-0204
IDI1_000932
Identhesin
KBio1_000932
KBio2_000474
KBio2_003042
KBio2_005610
KBio3_001408
KBioGR_000658
KBioSS_000474
Keloform
LS-35847
MLS001331704
MLS002153970
Methanesulfonate, Benzocaine
MolPort-000-871-526
NCGC00016352-01
NCGC00094598-01
NCGC00094598-02
NINDS_000932
NSC 122792
NSC 41531
NSC41531
NSC4688
Norcain
Norcaine
Norcainum
Oprea1_750694
Oprea1_827402
Ora-jel
Orabase-B
Orthesin
Otocain
Outgro
Parathesin
Parathesin (TN)
Parathesine
Prestwick0_000712
Prestwick1_000712
Prestwick2_000712
Prestwick3_000712
Prestwick_991
SMR000059025
SPBio_000134
SPBio_002844
SPECTRUM1500139
STK043620
Slim Mint Gum
Solarcaine
Solu H
Spectrum2_000117
Spectrum3_000314
Spectrum4_000249
Spectrum5_000860
Spectrum_000074
Topcaine
UNII-U3RSY48JW5
WLN: ZR DVO2
ZINC12358719
benzocaine
ethylaminobenzoate-4
h-4-abz-oet
nchembio.182-comp4
p-(Ethoxycarbonyl)aniline
p-Aminobenzoate
p-Aminobenzoic acid
p-Aminobenzoic acid ethyl ester
p-Aminobenzoic acid, ethyl ester
p-Aminobenzoic ethyl ester
p-Carbethoxyaniline
p-Ethoxycarboxylic Aniline
p-Ethoxycarboxylic aniline
24tannic acidapproved, Nutraceutical1892

Interventional clinical trials:

(show all 35)
idNameStatusNCT IDPhase
1Extension Study of the Efficacy and Safety of Deferasirox Treatment in Beta-thalassemia Patients With Transfusional Hemosiderosis (Study Amended to 2-year Duration)CompletedNCT00171301Phase 4
2Palatability and Tolerability of Deferasirox Taken With Meals, With Different Liquids or Crushed and Added to FoodCompletedNCT00845871Phase 4
3Efficacy Study in Removing Excess Iron From the HeartCompletedNCT00105495Phase 4
4ENTRUST, a 5 Year Surveillance of Children Aged 2 to <6 Years With Transfusional Iron Overload Treated With DeferasiroxCompletedNCT00466063Phase 4
5Safety and Efficacy of Desferasirox in Chinese Patients With Iron Overload and Aplastic AnemiaCompletedNCT01546415Phase 4
6Efficacy and Safety of Oral Deferasirox (20 mg/kg/d) in Pts 3 to 6 Months After Allogeneic Hematopoietic Cell Transplantation Who Present With Iron OverloadCompletedNCT00654589Phase 4
7Efficacy and Safety of Deferasirox in Patients With Myelodysplastic Syndrome and Transfusion-dependent Iron OverloadCompletedNCT00481143Phase 4
8The Potential Hepatoprotective Effect of Metformin in Patients With Beta Thalassemia MajorNot yet recruitingNCT02984475Phase 4
9Study Of Efficacy,Safety of Combined Deferasirox and Deferiprone Versus Combined Deferiprone and Desferal In Conditions of Iron OverloadUnknown statusNCT01511848Phase 2, Phase 3
10Safety, Tolerability, and Efficacy of Deferasirox in MDSCompletedNCT00469560Phase 3
11A Study of Long-term Treatment With Deferasirox in Patients With Beta-thalassemia and Transfusional HemosiderosisCompletedNCT00171171Phase 3
12Safety & Efficacy of ICL670 vs. Deferoxamine in Beta-thalassemia Patients With Iron Overload Due to Blood TransfusionsCompletedNCT00061750Phase 3
13Efficacy and Safety of Deferasirox in Patients With Chronic Anemia and Transfusional HemosiderosisCompletedNCT00631163Phase 2
14Safety of ICL670 vs. Deferoxamine in Sickle Cell Disease Patients With Iron Overload Due to Blood TransfusionsCompletedNCT00067080Phase 2
15Evaluating Use of Deferasirox as Compared to Deferoxamine in Treating Cardiac Iron OverloadCompletedNCT00600938Phase 2
16Extension Study of Iron Chelation Therapy With Deferasirox in β-thalassemia and Rare Chronic Anemia PatientsCompletedNCT00303329Phase 2
17Study of Deferasirox in Iron Overload From Beta-thalassemia Unable to be Treated With Deferoxamine or Chronic AnemiasCompletedNCT00061763Phase 2
18Evaluation of the Safety, Tolerability, Pharmacokinetics (PK) and Effects on Liver Iron Concentration of ICL670 Relative to Deferoxamine(DFO).CompletedNCT01090323Phase 2
19Treatment of Anemia With Epoetin Beta in Low Risk Myelodysplastic Syndrome (MDS)CompletedNCT02428686Phase 2
20A Protocol to Allow Treatment With ICL670 for Patients With or at Risk of Life-threatening Complications of Transfusional Iron Overload Who Are Unable to Tolerate Other Iron Chelators Because of Documented Severe ToxicityCompletedNCT01044186Phase 2
21The Deferasirox-calcium-vitamin D3 Therapy for Postmenopausal Osteoporosis (PMOP)Not yet recruitingNCT02854722Phase 2
22Treatment of Iron Overload Requiring Chelation TherapyWithdrawnNCT01927913Phase 2
23Single and Multiple Ascending Dose Study of Aducanumab (BIIB037) in Japanese Participants With Alzheimer's DiseaseCompletedNCT02434718Phase 1
24PHOX2B Mutation-Confirmed Congenital Central Hypoventilation Syndrome in A Chinese Family: Presentations From Newborn to AdulthoodUnknown statusNCT00652964
25Red Blood Cell Transfusion Thresholds and QOL in MDSUnknown statusNCT02099669
26Observation of Patients With Transfusional Hemosiderosis Treatment With DeferasiroxCompletedNCT01394029
27Pharmacogenetic Study in Patients Received Iron Chelating AgentCompletedNCT01623895
28Non-invasive Quantification of Liver Iron With MRICompletedNCT01516853
29Added Value of Speckle Tracking in the Evaluation of Patients With Sickle Cell DiseaseCompletedNCT02394431
30The Silent Cortical Infarcts in the Cerebral Amyloid Angiopathy: Is There a Link With Subarachnoid Hemorrhage?CompletedNCT02837354
31Confounder-Corrected Quantitative MRI Biomarker of Hepatic Iron ContentRecruitingNCT02025543
32Detection of β Thalassemia Carriers by Red Cell Parameters Obtained From the H2 Automatic CounterRecruitingNCT00481221
33A Case Control Study to Evaluate the Cognitive and Brain Function of β-thalassemia Patients.Enrolling by invitationNCT01935661
34Efficacy of Bone Marrow Mesenchymal Stem Cell in Pulmonary HemosiderosisNot yet recruitingNCT02985346Early Phase 1
35Florbetaben as an Amyloid Plaque Marker in Elderly Patients With Focal or Disseminated Superficial HemosiderosisNot yet recruitingNCT02664571

Search NIH Clinical Center for Hemosiderosis

Inferred drug relations via UMLS68/NDF-RT46:


Cochrane evidence based reviews: hemosiderosis

Genetic Tests for Hemosiderosis

About this section

Anatomical Context for Hemosiderosis

About this section

MalaCards organs/tissues related to Hemosiderosis:

36
Liver, Lung, Heart, Bone, Bone marrow, Brain, Kidney

Publications for Hemosiderosis

About this section

Articles related to Hemosiderosis:

(show top 50)    (show all 482)
idTitleAuthorsYear
1
A Case of Idiopathic Pulmonary Hemosiderosis Presenting With Signs and Symptoms Mimicking Hemolytic Anemia. (27918350)
2017
2
Helicobacter pylori Associated With Pulmonary Hemosiderosis. (26741588)
2016
3
Unusual presentation: Concurrent IgA deficiency and idiopathic pulmonary hemosiderosis. (27120139)
2016
4
Eculizumab treatment improved renal hemosiderosis in a patient with paroxysmal nocturnal hemoglobinuria. (27873177)
2016
5
Cor triatriatum sinister: a rare underlying cause of pulmonary hemosiderosis. (27026847)
2016
6
Correlation between Heart, Liver and Pancreas Hemosiderosis Measured by MRI T2* among Thalassemia Major Patients from Iran. (26838079)
2016
7
Severe Respiratory Distress in a Child with Pulmonary Idiopathic Hemosiderosis Initially Presenting with Iron-Deficiency Anemia. (26634166)
2015
8
Quantitative susceptibility mapping in superficial hemosiderosis of the central nervous system. (26054638)
2015
9
Idiopathic pulmonary hemosiderosis in adults: Review of cases reported in the latest 15 years. (26692115)
2015
10
Pulmonary Hemosiderosis Associated To Celiac Disease: Lane Hamilton Syndrome. (25944220)
2015
11
Idiopathic pulmonary hemosiderosis presenting in an adult: A case report and review of the literature. (26180395)
2015
12
Idiopathic Pulmonary Hemosiderosis Presenting as Anemia, Failure to Thrive, and Jaundice in a Toddler. (26414632)
2015
13
Unexplained childhood anaemia: idiopathic pulmonary hemosiderosis. (25904566)
2015
14
Idiopathic Pulmonary Hemosiderosis With Allergic Asthma Diagnosis in a Pediatric Patient. (26241728)
2015
15
YERSINIA PSEUDOTUBERCULOSIS, SEROGROUP O:1A, INFECTION IN TWO AMAZON PARROTS (AMAZONA AESTIVA AND AMAZONA ORATRIX) WITH HEPATIC HEMOSIDEROSIS. (26352966)
2015
16
A Rare Cause of Reversible Renal Hemosiderosis. (26491580)
2015
17
A young man with hemoptysis: Rare association of idiopathic pulmonary hemosiderosis, celiac disease and dilated cardiomyopathy. (25624603)
2015
18
Terminal ileum hemosiderosis secondary to prolonged oral iron ingestion. (25831064)
2015
19
A physician survey reveals differences in management of idiopathic pulmonary hemosiderosis. (26289251)
2015
20
Association of Celiac Disease With Idiopathic Pulmonary Hemosiderosis; Lane Hamilton Syndrome. (26495097)
2015
21
Idiopathic pulmonary hemosiderosis complicated by Down syndrome. (26508184)
2015
22
Pulmonary hemosiderosis in children with bronchopulmonary dysplasia. (25309768)
2014
23
Top Differential Diagnosis Should Be Microscopic Polyangiitis in ANCA-Positive Patient with Diffuse Pulmonary Hemorrhage and Hemosiderosis. (25525543)
2014
24
Donor hemosiderosis does not affect liver function and regeneration in the setting of living donor liver transplantation. (24354876)
2014
25
Superficial cerebral hemosiderosis in a patient treated with warfarin. (25556417)
2014
26
Renal hemosiderosis and rapidly progressive glomerulonephritis associated with primary hemochromatosis. (24588645)
2014
27
Neonatal pulmonary hemosiderosis. (25389504)
2014
28
Inverted cortico-medullary differentiation of renal hemosiderosis. (24434406)
2014
29
Idiopathic pulmonary hemosiderosis - a diagnostic challenge. (24708654)
2014
30
Secondary hemosiderosis on kidney biopsy in a patient with a left ventricular assist device. (24472821)
2014
31
Islet inflammation, hemosiderosis, and fibrosis in intrauterine growth-restricted and high fat-fed Sprague-Dawley rats. (24631026)
2014
32
Melioidosis and idiopathic pulmonary hemosiderosis: a cast-iron case. (25473541)
2013
33
Spondias pinnata stem bark extract lessens iron overloaded liver toxicity due to hemosiderosis in Swiss albino mice. (23293203)
2013
34
New insights into pediatric idiopathic pulmonary hemosiderosis: the French RespiRare(Ar) cohort. (24125570)
2013
35
Idiopathic pulmonary hemosiderosis presenting as a rare cause of iron deficiency anemia in a toddler--a diagnostic challenge. (23550400)
2013
36
The importance of evaluation of Celiac disease in patients with pulmonary hemosiderosis. (23550401)
2013
37
Extracorporeal life support for a 5-week-old infant with idiopathic pulmonary hemosiderosis. (23942745)
2013
38
A case report of hemosiderosis-induced ventricular pacing exit block. (23907043)
2013
39
Cerebral amyloid angiopathy with asymmetric superficial hemosiderosis and transient focal neurological symptoms. (23983893)
2013
40
Transfusional iron overload presenting as choroid plexus hemosiderosis. (24617189)
2013
41
Long-term liposteroid therapy for idiopathic pulmonary hemosiderosis. (23812505)
2013
42
Iron chelation with deferasirox for the treatment of secondary hemosiderosis in pediatric oncology patients: a single-center experience. (23669734)
2013
43
Child with idiopathic pulmonary hemosiderosis: a case report from Pakistan with multiple ethical and moral issues. (21968218)
2012
44
Eight Years Follow-up of a Case with Idiopathic Pulmonary Hemosiderosis After Corticosteroid Therapy. (22393549)
2012
45
Idiopathic pulmonary hemosiderosis in adults: a case report and review of the literature. (22851975)
2012
46
Cochlear implantation in patients affected by superficial hemosiderosis of the central nervous system. (21431954)
2012
47
Pulmonary hemosiderosis associated with celiac disease: improvement after a gluten-free diet. (22782615)
2012
48
Pulmonary hypoplasia on preterm infant associated with diffuse chorioamniotic hemosiderosis caused by intrauterine hemorrhage due to massive subchorial hematoma: report of a neonatal autopsy case. (22827763)
2012
49
Renal hemosiderosis complicating sickle cell anemia. (22419047)
2012
50
Hemodialysis-associated hemosiderosis in the era of erythropoiesis-stimulating agents: a MRI study. (22998881)
2012

Variations for Hemosiderosis

About this section

Expression for genes affiliated with Hemosiderosis

About this section
Search GEO for disease gene expression data for Hemosiderosis.

Pathways for genes affiliated with Hemosiderosis

About this section

GO Terms for genes affiliated with Hemosiderosis

About this section

Cellular components related to Hemosiderosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1HFE-transferrin receptor complexGO:199071210.3HFE, TF
2basal part of cellGO:004517810.2HFE, SLC11A2, TF
3early endosomeGO:000576910.2HFE, SLC11A2, TF
4blood microparticleGO:007256210.1CP, HBB, TF
5cell surfaceGO:00099869.6EPO, MIF, SLC11A2, TF
6recycling endosomeGO:00550379.3HFE, SLC11A2, TF
7extracellular regionGO:00055769.0CP, EPO, HBB, MIF, TF
8extracellular exosomeGO:00700628.1CAT, CP, GPT, HBB, MIF, TF
9extracellular spaceGO:00056157.5CAT, CP, EPO, GPT, HFE, MIF

Biological processes related to Hemosiderosis according to GeneCards Suite gene sharing:

(show all 16)
idNameGO IDScoreTop Affiliating Genes
1copper ion transportGO:000682510.4CP, SLC11A2
2cellular response to iron ionGO:007128110.3HFE, TF
3iron ion homeostasisGO:005507210.3HFE, TF
4positive regulation of receptor-mediated endocytosisGO:004826010.3HFE, TF
5acute-phase responseGO:000695310.3EPO, HFE
6multicellular organismal iron ion homeostasisGO:006058610.3HFE, SLC11A2
7response to iron ionGO:001003910.2HFE, SLC11A2
8negative regulation of myeloid cell apoptotic processGO:003303310.1EPO, MIF
9transferrin transportGO:00335729.8SLC11A2, TF
10cellular oxidant detoxificationGO:00988699.7CAT, HBB
11hydrogen peroxide catabolic processGO:00427449.7CAT, HBB
12response to hyperoxiaGO:00550939.7CAT, EPO
13cellular iron ion homeostasisGO:00068799.7CP, HFE, SLC11A2, TF
14response to hydrogen peroxideGO:00425429.6CAT, HBB
15response to vitamin AGO:00331899.6CAT, EPO
16agingGO:00075689.5CAT, CP, EPO

Molecular functions related to Hemosiderosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1transferrin receptor bindingGO:19904599.7HFE, TF
2receptor bindingGO:00051028.9CAT, HFE, MIF

Sources for Hemosiderosis

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet