MCID: HPR003
MIFTS: 45

Heparin-Induced Thrombocytopenia malady

Categories: Rare diseases, Blood diseases

Aliases & Classifications for Heparin-Induced Thrombocytopenia

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Sources:
46NIH Rare Diseases, 52Orphanet, 66UMLS, 29ICD10 via Orphanet, 67UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Heparin-Induced Thrombocytopenia:

Name: Heparin-Induced Thrombocytopenia 46 52 66
Hit 46 52
Heparin-Induced Thrombocytopenia Type 2 52
 
Heparin-Associated Thrombocytopenia 52
Hat 52

Characteristics:

Orphanet epidemiological data:

52
heparin-induced thrombocytopenia:
Inheritance: Not applicable; Age of onset: All ages

Classifications:



External Ids:

Orphanet52 ORPHA3325
ICD10 via Orphanet29 D69.5
UMLS via Orphanet67 C0272285

Summaries for Heparin-Induced Thrombocytopenia

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NIH Rare Diseases:46 Heparin-induced thrombocytopenia (hit) is an adverse reaction to the drug heparin resulting in an abnormally low amount of platelets (thrombocytopenia). hit is usually an immune response which typically occurs 4-10 days after exposure to heparin; it can lead to serious complications and be life-threatening. this condition occurs in up to 5% of those who are exposed to heparin. characteristic signs of hit are a drop in platelet count of  greater than 50% and/or the formation of new blood clots during heparin therapy.  the first step of treatment is to discontinue and avoid all heparin products immediately. often, affected individuals require another medicine to prevent blood clotting (anticoagulants). last updated: 5/3/2012

MalaCards based summary: Heparin-Induced Thrombocytopenia, also known as hit, is related to budd-chiari syndrome and splenic infarction, and has symptoms including pathergy reaction and mahler sign. An important gene associated with Heparin-Induced Thrombocytopenia is F3 (Coagulation Factor III, Tissue Factor), and among its related pathways are IgA-Producing B Cells in the Intestine and Platelet activation, signaling and aggregation. Affiliated tissues include testes, heart and liver, and related mouse phenotypes are cardiovascular system and mortality/aging.

Wikipedia:69 Heparin-induced thrombocytopenia (HIT) is the development of thrombocytopenia (a low platelet count),... more...

Related Diseases for Heparin-Induced Thrombocytopenia

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Diseases related to Heparin-Induced Thrombocytopenia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 155)
idRelated DiseaseScoreTop Affiliating Genes
1budd-chiari syndrome30.9F5, SERPINC1
2splenic infarction29.9CD40LG, F3
3myocardial infarction29.2F10, F3, F5, SERPINC1
4systemic lupus erythematosus28.8CD40LG, F3, FCGR2A
5thrombocytopenia11.3
6ariboflavinosis10.5F3, SERPINC1
7cavernous sinus thrombosis10.5F3, SERPINC1
8cavernous hemangioma of face10.5F3, SERPINC1
9ovarian gonadoblastoma10.4F3, SERPINC1
10dmd-related dilated cardiomyopathy10.4F3, SERPINC1
11lateral cystocele10.4F3, SERPINC1
12pulmonary embolism10.4
13chronic diarrhea due to guanylate cyclase 2c overactivity10.4F3, SERPINC1
14lymphatic system cancer10.4F3, SERPINC1
15perichondritis of auricle10.4F3, SERPINC1
16acquired fructose intolerance10.4F3, F5
17coronary restenosis10.4F3, SERPINC1
18classic congenital lipoid adrenal hyperplasia due to star deficency10.4F3, F5
19cerebritis10.4
20colon carcinoma in situ10.4F3, SERPINC1
21antiphospholipid syndrome10.4
22subcortical arteriosclerotic encephalopathy10.3F5, SERPINC1
23dermatitis10.3F3, SERPINC1
24facioscapulohumeral muscular dystrophy 110.3F3, F5
25tollner horst manzke syndrome10.3F3, SERPINC1
26thyroid hyalinizing trabecular adenoma10.3F5, SERPINC1
27fiedler's myocarditis10.3F3, SERPINC1
28collagenous colitis10.3F5, SERPINC1
29may-hegglin anomaly10.3F5, SERPINC1
30left-right axis malformations10.3F5, SERPINC1
31polyhydramnios10.3F5, SERPINC1
32infantile-onset ascending hereditary spastic paralysis10.3F3, F5
33functional colonic disease10.3F5, SERPINC1
34microcytic anemia10.3F3, SERPINC1
35thrombophilia10.3F5, SERPINC1
36focal epilepsy10.3F3, SERPINC1
37selective iga deficiency disease10.3F5, SERPINC1
38glossopharyngeal nerve disease10.3F10, F3
39mastocytosis cutaneous with short stature conductive hearing loss and microtia10.3FCGR2A, SERPINC1
40thrombocytopenia with elevated serum iga and renal disease10.3F3, F5
41angina pectoris10.2F3, SERPINC1
42joint disorders10.2F5, SERPINC1
43dentinogenesis imperfecta10.2F3, FCGR2A
44paroxysmal nocturnal hemoglobinuria10.2
45hemoglobinuria10.2
46aneurysm10.2
47exophthalmic ophthalmoplegia10.2F5, SERPINC1
48scapuloperoneal myopathy, x-linked dominant10.2F10, F3
49endotheliitis10.2
50preeclampsia/eclampsia 110.1F5, SERPINC1

Graphical network of the top 20 diseases related to Heparin-Induced Thrombocytopenia:



Diseases related to heparin-induced thrombocytopenia

Symptoms for Heparin-Induced Thrombocytopenia

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UMLS symptoms related to Heparin-Induced Thrombocytopenia:


pathergy reaction, mahler sign

Drugs & Therapeutics for Heparin-Induced Thrombocytopenia

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Drugs for Heparin-Induced Thrombocytopenia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 26)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
DalteparinPhase 4, Phase 3, Phase 1, Phase 22899041-08-1
Synonyms:
Daltepariininatrium
Dalteparin Sodyum
Dalteparin sodium
Dalteparin sodná sůl
Dalteparin-nátrium
Dalteparina sódica
 
Dalteparinnatrium
Dalteparino natrio druska
Dalteparinum Natricum
Dalteparyna sodowa
Daltéparine sodique
Heparin Fragment KABI 2165
Tedelparin
2THROMBINPhase 4, Phase 3, Phase 2284
3NadroparinPhase 4329041-08-1
4
BivalirudinPhase 4, Phase 366128270-60-016129704
Synonyms:
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-4-amino-2-[[2-[[2-[[2-[[2-[[(2S)-1-[(2S)-2-[[(2S)-1-[(2R)-2-amino-3-cyclohexylpropanoyl]pyrrolidine-2-carbonyl]amino]-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]amino]acetyl]amino]acetyl]amino]acetyl]amino]acetyl]amino]-4-oxobutanoyl]amino]acetyl]amino]-4-hydroxy-4-oxobutanoyl]amino]-3-cyclohexylpropanoyl]amino]-5-hydroxy-5-oxopentanoyl]amino]-5-hydroxy-5-oxopentanoyl]amino]-3-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-5-hydroxy-5-oxopentanoyl]amino]-5-hydroxy-5-oxopentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoic acid
128270-60-0
Angiomax
BG 8967
BG-8967
BG8967
Bivalirudin
Bivalirudin [USAN:BAN:INN]
C074619
C9H11NO.C2H6.CH4
CHEBI:59173
D-Phenylalanyl-L-prolyl-L-arginyl-L-prolylglycylglycylglycylglycyl-L-asparaginylglycyl-L-alpha-aspartyl-L-phenylalanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-isoleucyl-L-prolyl-L-alpha-glutamyl-L-alpha-glutamyl-L-tyrosyl-L-leucine
 
DB02351
HS-2004
Hirulog
Hirulog-1
LS-172701
Phe-Pro-Arg-Pro-(Gly)4 desulfato-Tyr63'-hirugen
Phe-Pro-Arg-Pro-(Gly)4-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu
Phe-Pro-Arg-Pro-(Gly)4-desulfohirudin-(53-64)
The Medicines Company brand of bivalirudin
UNII-TN9BEX005G
bivalirudina
bivalirudine
bivalirudinum
5fondaparinuxPhase 4, Phase 2, Phase 3, Phase 180
6
desirudinPhase 4, Phase 2, Phase 37120993-53-5
Synonyms:
63-Desulfohirudin
63-Desulfohirudin (Hirudo Medicinalis Isoform HV1)
 
63-Desulfohirudin (recombinant)
Desirudin recombinant
Hirudin desirudin
7
LepirudinPhase 45120993-53-5, 138068-37-816132441
Synonyms:
1-L-Leucine-2-L-threonine-63-desulfohirudin (Hirudo medicinalis isoform HV1)
1-Leu-2-thr-63-desulfohirudin
138068-37-8
Aventis Behring Brand of Lepirudin
Aventis Brand Lepirudin
Aventis Pharma Brand of Lepirudin
Berlex Brand of Lepirudin
C083544
Hbw 023
Hbw-023
 
Hirudin variant-1
Hoechst Brand of Lepirudin
LS-186968
LS-187612
Lepirudin
Lepirudin recombinant
Pharmion Brand of Lepirudin
Refludan
Refludin
Schering Brand of Lepirudin
UNII-Y43GF64R34
8
HeparinPhase 4, Phase 3, Phase 2, Phase 17799005-49-6772, 46507594
Synonyms:
101921-26-0
102-94-3
102785-31-9
104521-37-1
11078-24-3
11129-39-8
12656-11-0
2-o-sulfohexopyranuronosyl-(1->4)-2-deoxy-3-o-sulfo-2-(sulfoamino)hexopyranosyl-(1->4)-2-o-sulfohexopyranuronosyl-(1->4)-2-acetamido-2-deoxy-6-o-sulfohexopyranose
37324-73-5
6-[6-[6-[5-acetamido-4,6-dihydroxy-2-(sulfooxymethyl)oxan-3-yl]oxy-2-carboxy-4-hydroxy-5-sulfooxyoxan-3-yl]oxy-2-(hydroxymethyl)-5-(sulfoamino)-4-sulfooxyoxan-3-yl]oxy-3,4-dihydroxy-5-sulfooxyoxane-2-carboxylic acid
9041-08-1
9045-22-1
9075-96-1
913079-23-9
91449-79-5
AC1L19ZN
AC1L1ROY
ALFA 87-120
ALFA 87-163
ALFA 87-198
ALFA 87-81
ALFA 88-247
AR-1E4539
Allocinnamic acid
Ardeparin
Ardeparin sodium
Arteven
Bemiparin
Bemiparin sodium
CID772
CID8784
CY 216
Calciparine
Certoparin
Clexane
Clivarin
Clivarine
Cy 222
D006495
D017984
DB00407
DB01225
Dalteparin
Dalteparin sodium
Depo-Heparin
EINECS 232-681-7
EMT 966
EMT 967
EMT-966
EMT-967
EMT966
EMT967
Enoxaparin
Enoxaparin sodium
Enoxaparine
Eparina
Eparina [DCIT]
FR 860
Fluxum
Fragmin A
Fragmin B
Fragmin IV
Fraxiparin
H 2149
HSDB 3094
Hed-heparin
Hep Flush Kit in plastic container
Hep-Lock
Hep-Lock U/P
Hep-lock
Heparin
Heparin CY 216
Heparin Lock Flush
Heparin Lock Flush in plastic container
Heparin Lock Flush preservative free
Heparin Lock Flush preservative free in plastic container
Heparin Sodium
Heparin natrium
Heparin sodium
Heparin sodium 1,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 1,000 units in dextrose 5% in plastic container
Heparin sodium 1,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 10,000 units in dextrose 5%
Heparin sodium 10,000 units in dextrose 5% in plastic container
Heparin sodium 10,000 units in sodium chloride 0.45%
Heparin sodium 10,000 units in sodium chloride 0.9%
Heparin sodium 12,500 units in dextrose 5%
Heparin sodium 12,500 units in dextrose 5% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.45% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.9%
Heparin sodium 2,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 2,000 units in dextrose 5% in plastic container
Heparin sodium 2,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 20,000 units and dextrose 5% in plastic container
Heparin sodium 20,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units and dextrose 5% in plastic container
 
Heparin sodium 25,000 units in dextrose 5%
Heparin sodium 25,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.45% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.9%
Heparin sodium 25,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units in dextrose 5% in plastic container
Heparin sodium 5,000 units in sodium chloride 0.45%
Heparin sodium 5,000 units in sodium chloride 0.9%
Heparin sodium 5,000 units in sodium chloride 0.9% in plastic container
Heparin sodium in plastic container
Heparin sodium preservative Free
Heparin sulfate
Heparin sulphate
Heparin, Low Molecular Weight
Heparin, Low-Molecular-Weight
Heparin, sodium salt
Heparina
Heparina [INN-Spanish]
Heparinate
Heparine
Heparine [INN-French]
Heparinic acid
Heparinsodiumsalt
Heparinum
Heparinum [INN-Latin]
Heparinum natricum
Hepathrom
Hepflush-10
Inno-Hep
Innohep
Isocinnamic acid
KB 101
Kabi 2165
LHN 1
LMWH
Lioton 1000
Lipo-hepin
Liquaemin
Liquaemin Lock Flush
Liquaemin Sodium
Liquaemin sodium preservative free
Liquemin
Logiparin
Lovenox
Lovenox HP
Low Molecular Weight Heparin
Low molecular weight heparin
Low molecular weight heparin sodium
Low-Molecular-Weight Heparin
Minolteparin sodium
MolPort-003-760-257
Multiparin
NSC174025
Nadroparin
Nadroparine
Novoheparin
OP 386
OP 622
Octaparin
PK 10,169
PK-10,169
PK-10169
PK10,169
PK10169
Pabyrin
Panheprin
Parnaparin
Parnaparin sodium
Parvoparin
Pularin
Reviparin
Reviparin sodium
Ro 11
Sandoparin
Sodium acid heparin
Sodium heparin
Sodium heparinate
Subeparin
Sublingula
Thromboliquine
Tinzaparin
Tinzaparin sodium
Triofiban
UNII-12M44VTJ7B
UNII-3S182ET3UA
UNII-E47C0NF7LV
UNII-T2410KM04A
UNII-ZZ45AB24CA
Unfractionated heparin
Vetren
Vitrum AB
WY 90493RD
alpha-Heparin
cis-.beta.-Carboxystyrene
cis-Cinnamic acid
enoxaparin
heparin
9calcium heparinPhase 4, Phase 3, Phase 2, Phase 1779
10
protease inhibitorsPhase 4, Phase 3, Phase 25157
Synonyms:
 
protease inhibitors
11
ArgatrobanPhase 4, Phase 3, Phase 21874863-84-6152951
Synonyms:
(2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[(3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonylamino]pentanoyl]-4-methylpiperidine-2-carboxylic acid
(2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(3R)-3-methyl-1,2,3,4-tetrahydroquinolin-8-yl]sulfonylamino]pentanoyl]-4-methylpiperidine-2-carboxylic acid
(2R,4R)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(3S)-3-methyl-1,2,3,4-tetrahydroquinolin-8-yl]sulfonylamino]pentanoyl]-4-methylpiperidine-2-carboxylic acid
(2R,4R)-1-[5-(diaminomethylideneamino)-2-[(3-methyl-1,2,3,4-tetrahydroquinolin-8-yl)sulfonylamino]pentanoyl]-4-methylpiperidine-2-carboxylic acid
(2R,4R)-4-Methyl-1-((S)-N(sup 2)-(((RS)-1,2,3,4-tetrahydro-3-methyl-8-quinolyl)sulfonyl)arginyl)pipecolic acid
(2R,4R)-4-Methyl-1[Nalpha-[(3-methyl-1,2,3,4-tetrahydro-8-quinolinyl)sulfonyl]-L-arginyl)]-2-piperadinecarboxylic acid
(2r,4r)-4-methyl-1-[n2-(3-methyl-1,2,3,4-tetrahydro-8-quinolinesulfonyl)-l-arginyl]-2-piperidinecarboxylic acid
121785-71-5
1dwc
21R-Argatroban
4-methyl-1-(N(2)-(3-methyl-1,2,3,4-tetrahydro-8-quinolinesulfonyl)-L-arginyl)-2-piperidinecarboxylic acid
74863-84-6
82784-65-4
AC-15185
AC1L3OPA
AC1L49F4
AC1L99H9
AC1L9HII
AC1Q5QXC
AR-1A3021
Acova
Argatroban (anhydrous)
Argatroban [INN:JAN]
Argatrobanum
Argatrobanum [Latin]
BIDD:GT0748
C04931
C23H36N6O5S
CHEBI:194249
CHEBI:288815
CHEMBL1166
 
CHEMBL59461
CID152951
CID440542
CID445156
CID92722
CPD000466348
DB00278
GN-1600
HMS2051N07
HMS2090L12
KST-1A8419
LS-114621
LS-114640
MCI 9038
MCI-9038
MD 805
MD-805
MD805
MITSUBISHI INHIBITOR
MLS000759461
MLS001424093
MMTQAP
MPQA
MQI-ARG-MCP
MolPort-003-987-205
NCGC00164592-01
NCGC00166413-01
Novastan
SAM001246661
SMR000466348
TL8005144
UNII-OCY3U280Y3
argatroban
12CertoparinPhase 47
13
WarfarinPhase 4, Phase 244181-81-26691, 54678486
Synonyms:
(-)-Warfarin
(S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone
(S)-Warfarin
(phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarin
(phenyl-1 acetyl-2 ethyl) 3-hydroxy-4 coumarine
1-(4'-Hydroxy-3'-coumarinyl)-1-phenyl-3-butanone
200 Coumarin
200 coumarin
3-(1'-Phenyl-2'-acetylethyl)-4-hydroxycoumarin
3-(Acetonylbenzyl)-4-hydroxycoumarin
3-(alpha-Acetonylbenzyl)-4-hydroxycoumarin
3-(alpha-Phenyl-beta-acetylaethyl)-4-hydroxycumarin
3-(alpha-Phenyl-beta-acetylethyl)-4-hydroxycoumarin
4-Hydroxy-3- (3-oxo-1-fenyl-butyl) cumarine
4-Hydroxy-3- (3-oxo-1-phenyl-butyl)-cumarin
4-Hydroxy-3-(3-oxo-1-fenyl-butyl) cumarine
4-Hydroxy-3-(3-oxo-1-phenyl-butyl)-cumarin
4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one
4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one
4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin
4-Idrossi-3- (3-oxo-)-fenil-butil)-cumarine
4-Idrossi-3-(3-oxo-)-fenil-butil)-cumarine
4-Idrossi-3-(3-oxo-1-fenil-butil)-cumarine
45706_FLUKA
45706_RIEDEL
4oh-coumarin deriv.
5543-56-6
5543-57-7
81-81-2
A2250_FLUKA
A2250_SIGMA
AC-15978
AC1L1N37
AC1Q6AN3
AR-1E2310
Arab Rat Death
Arab rat death
Arab rat deth
Athrombin
Athrombin-K
Athrombin-k
Athrombine-K
Athrombine-k
BRD-A24514565-001-02-2
BRD-A24514565-236-01-6
BRN 1293536
BSPBio_002026
Bio-0586
Brumolin
C01541
C19H16O4
CBDivE_002127
CBDivE_013236
CBKinase1_000192
CBKinase1_012592
CHEBI:10033
CHEMBL1464
CID6691
CO-Rax
Caswell No. 903
Choice
Choice (TN)
Co-Rax
Co-rax
Compound 42
Coumadin
Coumadin Tabs
Coumafen
Coumafene
Coumafene [French]
Coumaphen
Coumaphene
Coumarins
Coumefene
Cov-R-Tox
Cov-R-tox
D-Con
D08682
DB00682
DL-3-(alpha-acetonylbenzyl)-4-hydroxycoumarin
Dethmor
Dethnel
Dicusat E
Dicusat e
DivK1c_000444
EINECS 201-377-6
EINECS 226-907-3
EPA Pesticide Chemical Code 086002
Eastern states duocide
Fasco fascrat powder
Frass-Ratron
Frass-ratron
HMS1921K07
HMS2092C20
HMS501G06
HSDB 1786
I14-0958
IDI1_000444
Jantoven
KBio1_000444
KBio2_000674
KBio2_003242
KBio2_005810
KBio3_001526
KBioGR_000901
KBioSS_000674
Killgerm sewarin p
Kumader
Kumadu
Kumatox
Kypfarin
LS-55083
Latka 42
Latka 42 [Czech]
Liqua-tox
MLS001304042
Maag Rattentod Cum
Maag rattentod cum
Mar-Frin
Mar-frin
Marevan
Martin'S mar-frin
Martin's mar-frin
 
Maveran
MolPort-001-787-822
Mouse pak
NCGC00094810-01
NCGC00094810-02
NCGC00159398-03
NCGC00178855-01
NINDS_000444
NSC 59813
NSC59813
PS104_SUPELCO
Panwarfin
Place-Pax
Place-pax
Prothromadin
RAX
RCR grey squirrel killer concentrate
RCRA waste no. P001
Rat & mice bait
Rat and mice bait
Rat-B-gon
Rat-Gard
Rat-Kill
Rat-Mix
Rat-O-cide #2
Rat-O-cide no. 2
Rat-Ola
Rat-Trol
Rat-a-way
Rat-alpha-way
Rat-b-gon
Rat-beta-gon
Rat-gard
Rat-kill
Rat-mix
Rat-o-cide #2
Rat-ola
Rat-trol
Ratorex
Ratox
Ratoxin
Ratron
Ratron G
Ratron g
Rats-no-more
Ratten-Koederrohr
Ratten-koederrohr
Rattenstreupulver Neu Schacht
Rattenstreupulver neu schacht
Rattenstreupulver new schacht
Rattentraenke
Rattunal
Rcra waste number P001
Ro-Deth
Ro-deth
Rodafarin
Rodafarin C
Rodafarin c
Rodex
Rodex blox
Rosex
Rough & ready mouse mix
Rough and ready mouse mix
SMP1_000316
SMR000718754
SPBio_000870
SPECTRUM1500613
STK364490
Sakarat
Sewarin
Sofarin
Solfarin
Sorexa Plus
Sorexa plus
Spectrum2_000935
Spectrum3_000583
Spectrum4_000381
Spectrum5_001751
Spectrum_000194
Spray-trol brand roden-trol
Temus W
Temus w
Tintorane
Tox-Hid
Tox-hid
Twin light rat away
UNII-5Q7ZVV76EI
Vampirinip II
Vampirinip III
Vampirinip iii
W.A.R.F. 42
WARF compound 42
WLN: T66 BOVJ DYR&1V1 EQ
Waran
Warf 10
Warf 42
Warfarat
Warfarin (INN)
Warfarin (and salts of)
Warfarin Plus
Warfarin Q
Warfarin [BSI:ISO]
Warfarin [INN:BAN]
Warfarin plus
Warfarin plus [discontinued]
Warfarin sodium
Warfarin titrated to an INR of 2.5-3.0
Warfarin(R)
Warfarina
Warfarina [INN-Spanish]
Warfarine
Warfarine [INN-French]
Warfarine [ISO-French]
Warfarinum
Warfarinum [INN-Latin]
Warficide
Warfilone
Zoocoumarin
Zoocoumarin [Netherlands and USSR]
Zoocoumarin [Russian]
delta-Con
nchembio.307-comp19
rac-Warfarin
warfarin
14
bilirubinPhase 4107635-65-45280352
Synonyms:
(4Z,15Z)-Bilirubin IXa
(Z,Z)-Bilirubin IXa
1,10,19,22,23,24-Hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-Biline-8,12-dipropionate
1,10,19,22,23,24-Hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-Biline-8,12-dipropionic acid
2,17-Diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-Biline-8,12-dipropanoate
2,17-Diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-Biline-8,12-dipropanoic acid
3-(2-((3-(2-Carboxyethyl)-4-methyl-5-((3-methyl-5-oxo-4-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-2-yl)methyl)-4-methyl-5-((4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-3-yl)propanoate
3-(2-((3-(2-Carboxyethyl)-4-methyl-5-((3-methyl-5-oxo-4-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-2-yl)methyl)-4-methyl-5-((4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid
 
3-(2-((3-(2-Carboxyethyl)-4-methyl-5-[(Z)-(3-methyl-5-oxo-4-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-1H-pyrrol-2-yl)methyl)-4-methyl-5-[(Z)-(4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene
3-[2-[[3-(2-Carboxyethyl)-5-[(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoate
3-[2-[[3-(2-Carboxyethyl)-5-[(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
3-[2-[[3-(2-Carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(Z)-(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoate
3-[2-[[3-(2-Carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(Z)-(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
Bilirubin
Bilirubin IX-alpha
Cholerythrin
Hematoidin
15serineNutraceuticalPhase 4, Phase 3, Phase 2883
16
RivaroxabanPhase 3, Phase 2233366789-02-8
Synonyms:
BAY 59-7939
 
BAY59-7939
Xarelto
17
BenzocainePhase 317941994-09-7, 94-09-72337
Synonyms:
(p-(Ethoxycarbonyl)phenylamine
06952_FLUKA
112909_ALDRICH
112909_SIAL
1333-08-0
23239-88-5
23239-88-5 (hydrochloride)
4 Aminobenzoic Acid Ethyl Ester
4-(Ethoxycarbonyl)aniline
4-(Ethoxycarbonyl)phenylamine
4-14-00-01129 (Beilstein Handbook Reference)
4-Aminobenzoate
4-Aminobenzoic acid
4-Aminobenzoic acid ethyl ester
4-Aminobenzoic acid, ethyl ester
4-Carbethoxyaniline
4-amino-benzoic acid ethyl ester
4-aminobenzoic acid ethyl ester
71123-91-6
94-09-7
94-09-7 (Parent)
A0271
AB00051923
AC1L1DGC
AC1Q341A
AC1Q64JE
AE-562/40377256
AI3-02081
AKOS000119763
AR-1H9065
Acetate, Benzocaine
Aethoform
Aethylium paraminobenzoicum
Amben ethyl ester
Americaine
Anaesthan-syngala
Anaesthesin
Anaesthesinum
Anaesthin
Anestezin
Anestezin [Russian]
Anesthesin
Anesthesine
Anesthone
BB_SC-0019
BPBio1_001017
BRD-K75466013-001-05-2
BRN 0638434
BSPBio_000923
BSPBio_001908
Baby Anbesol
Bensokain
Benzoak
Benzocaina
Benzocaina [INN-Spanish]
Benzocaine
Benzocaine (USP/INN)
Benzocaine Acetate
Benzocaine Formate
Benzocaine Hydrobromide
Benzocaine Hydrochloride
Benzocaine Methanesulfonate
Benzocaine [INN:BAN]
Benzocainum
Benzocainum [INN-Latin]
Benzoic acid, 4-amino-, ethyl ester
Benzoic acid, 4-amino-, ethyl ester, hydrochloride
Benzoic acid, amino-, ethyl ester
Benzoic acid, p-amino-, ethyl ester
C07527
CAS-94-09-7
CHEBI:116735
CHEMBL278172
CID2337
Caswell No. 430A
Chloraseptic
D001566
D00552
DB01086
Dermoplast
Diet Ayds
DivK1c_000932
E1501_SIGMA
EINECS 202-303-5
EPA Pesticide Chemical Code 097001
ETHYL-P-AMINOBENZOATE
Ethoform
Ethoforme
Ethyl 4-aminobenzoate
Ethyl 4-aminobenzoate hydrochloride
Ethyl 4-aminobenzoic acid
Ethyl Aminobenzoate
Ethyl PABA
 
Ethyl aminobenzoate
Ethyl aminobenzoate (JP15)
Ethyl aminobenzoate (VAN)
Ethyl aminobenzoic acid
Ethyl p-Aminobenzoate
Ethyl p-Aminophenylcarboxylate
Ethyl p-aminobenzenecarboxylate
Ethyl p-aminobenzoate
Ethyl p-aminobenzoic acid
Ethyl p-aminophenylcarboxylate
Ethylester kyseliny p-aminobenzoove
Ethylester kyseliny p-aminobenzoove [Czech]
Ethylis aminobenzoas
Formate, Benzocaine
HMS1570O05
HMS1920G09
HMS2091M11
HMS502O14
HSDB 7225
Hurricaine
Hydrobromide, Benzocaine
Hydrochloride, Benzocaine
I05-0204
IDI1_000932
Identhesin
KBio1_000932
KBio2_000474
KBio2_003042
KBio2_005610
KBio3_001408
KBioGR_000658
KBioSS_000474
Keloform
LS-35847
MLS001331704
MLS002153970
Methanesulfonate, Benzocaine
MolPort-000-871-526
NCGC00016352-01
NCGC00094598-01
NCGC00094598-02
NINDS_000932
NSC 122792
NSC 41531
NSC41531
NSC4688
Norcain
Norcaine
Norcainum
Oprea1_750694
Oprea1_827402
Ora-jel
Orabase-B
Orthesin
Otocain
Outgro
Parathesin
Parathesin (TN)
Parathesine
Prestwick0_000712
Prestwick1_000712
Prestwick2_000712
Prestwick3_000712
Prestwick_991
SMR000059025
SPBio_000134
SPBio_002844
SPECTRUM1500139
STK043620
Slim Mint Gum
Solarcaine
Solu H
Spectrum2_000117
Spectrum3_000314
Spectrum4_000249
Spectrum5_000860
Spectrum_000074
Topcaine
UNII-U3RSY48JW5
WLN: ZR DVO2
ZINC12358719
benzocaine
ethylaminobenzoate-4
h-4-abz-oet
nchembio.182-comp4
p-(Ethoxycarbonyl)aniline
p-Aminobenzoate
p-Aminobenzoic acid
p-Aminobenzoic acid ethyl ester
p-Aminobenzoic acid, ethyl ester
p-Aminobenzoic ethyl ester
p-Carbethoxyaniline
p-Ethoxycarboxylic Aniline
p-Ethoxycarboxylic aniline
18KavaNutraceuticalPhase 2, Phase 31379000-38-8
19
CreatineNutraceuticalPhase 2, Phase 311057-00-1586
Synonyms:
((amino(Imino)methyl)(methyl)amino)acetic acid
((amino(imino)methyl)(methyl)amino)acetate
((amino(imino)methyl)(methyl)amino)acetic acid
(N-methylcarbamimidamido)acetic acid
(alpha-Methylguanido)acetate
(alpha-Methylguanido)acetic acid
(α-methylguanido)acetic acid
Cosmocair C 100
Creatin
Creatine
Creatine hydrate
Kreatin
 
Krebiozon
Methylglycocyamine
Methylguanidoacetate
Methylguanidoacetic acid
N-(Aminoiminomethyl)-N-Methyl-Glycine
N-(aminoiminomethyl)-N-methylglycine
N-Amidinosarcosine
N-Carbamimidoyl-N-methylglycine
N-Methyl-N-guanylglycine
N-[(e)-AMINO(imino)methyl]-N-methylglycine
Phosphagen
[[Amino(imino)methyl](methyl)amino]acetate
[[Amino(imino)methyl](methyl)amino]acetic acid
alpha-Methylguanidino acetic acid
20tannic acidNutraceuticalPhase 31794
21
SerotoninPhase 1351050-67-95202
Synonyms:
3-(2-Aminoethyl)-1H-indol-5-ol
3-(2-Aminoethyl)indol-5-ol
3-(b-Aminoethyl)-5-hydroxyindole
5-HT
5-HTA
5-Hydroxy-3-(b-aminoethyl)indole
 
5-Hydroxy-tryptamine
5-Hydroxyltryptamine
5-Hydroxytriptamine
5-Hydroxytryptamine
Antemovis
DS substance
Enteramin
Enteramine
22DERMATAN SULFATE1
23Heparinoids4
24
Tinzaparin379005-49-6, 9041-08-125244225
Synonyms:
101921-26-0
102-94-3
102785-31-9
104521-37-1
11078-24-3
11129-39-8
12656-11-0
37324-73-5
9041-08-1
9045-22-1
9075-96-1
913079-23-9
91449-79-5
AC1L1ROY
ALFA 87-120
ALFA 87-163
ALFA 87-198
ALFA 87-81
ALFA 88-247
Allocinnamic acid
Ardeparin
Ardeparin sodium
Arteven
Bemiparin
Bemiparin sodium
CID8784
CY 216
Certoparin
Clivarin
Clivarine
Cy 222
Dalteparin
Dalteparin sodium
Depo-Heparin
EINECS 232-681-7
Enoxaparin sodium
Eparina
Eparina [DCIT]
FR 860
Fluxum
Fragmin A
Fragmin B
Fragmin IV
Fraxiparin
H 2149
HSDB 3094
Hed-heparin
Hep Flush Kit in plastic container
Hep-Lock
Hep-Lock U/P
Heparin CY 216
Heparin Lock Flush
Heparin Lock Flush in plastic container
Heparin Lock Flush preservative free
Heparin Lock Flush preservative free in plastic container
Heparin natrium
Heparin sodium
Heparin sodium 1,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 1,000 units in dextrose 5% in plastic container
Heparin sodium 1,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 10,000 units in dextrose 5%
Heparin sodium 10,000 units in dextrose 5% in plastic container
Heparin sodium 10,000 units in sodium chloride 0.45%
Heparin sodium 10,000 units in sodium chloride 0.9%
Heparin sodium 12,500 units in dextrose 5%
Heparin sodium 12,500 units in dextrose 5% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.45% in plastic container
Heparin sodium 12,500 units in sodium chloride 0.9%
Heparin sodium 2,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 2,000 units in dextrose 5% in plastic container
Heparin sodium 2,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 20,000 units and dextrose 5% in plastic container
Heparin sodium 20,000 units in dextrose 5% in plastic container
Heparin sodium 25,000 units and dextrose 5% in plastic container
Heparin sodium 25,000 units in dextrose 5%
Heparin sodium 25,000 units in dextrose 5% in plastic container
 
Heparin sodium 25,000 units in sodium chloride 0.45% in plastic container
Heparin sodium 25,000 units in sodium chloride 0.9%
Heparin sodium 25,000 units in sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units and sodium chloride 0.9% in plastic container
Heparin sodium 5,000 units in dextrose 5% in plastic container
Heparin sodium 5,000 units in sodium chloride 0.45%
Heparin sodium 5,000 units in sodium chloride 0.9%
Heparin sodium 5,000 units in sodium chloride 0.9% in plastic container
Heparin sodium in plastic container
Heparin sodium preservative Free
Heparin sulfate
Heparin, sodium salt
Heparina
Heparina [INN-Spanish]
Heparinate
Heparine
Heparine [INN-French]
Heparinic acid
Heparinum
Heparinum [INN-Latin]
Heparinum natricum
Hepathrom
Hepflush-10
Inno-Hep
Innohep
Isocinnamic acid
KB 101
Kabi 2165
LHN 1
Lioton 1000
Lipo-hepin
Liquaemin
Liquaemin Lock Flush
Liquaemin Sodium
Liquaemin sodium preservative free
Liquemin
Logiparin
Minolteparin sodium
MolPort-003-760-257
Multiparin
NSC174025
Nadroparin
Nadroparine
Novoheparin
OP 386
OP 622
Octaparin
Pabyrin
Panheprin
Parnaparin
Parnaparin sodium
Parvoparin
Pularin
Reviparin
Reviparin sodium
Ro 11
Sandoparin
Sodium acid heparin
Sodium heparin
Sodium heparinate
Subeparin
Sublingula
Thromboliquine
Tinzaparin
Tinzaparin sodium
Triofiban
UNII-12M44VTJ7B
UNII-3S182ET3UA
UNII-E47C0NF7LV
UNII-T2410KM04A
UNII-ZZ45AB24CA
Vetren
Vitrum AB
WY 90493RD
alpha-Heparin
cis-.beta.-Carboxystyrene
cis-Cinnamic acid
heparin
25
Menthol21842216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol
26histidineNutraceutical37

Interventional clinical trials:

(show top 50)    (show all 54)
idNameStatusNCT IDPhase
1Bivalirudin PCI Registry in Heparin Induced Thrombocytopenia/Heparin Induced Thrombocytopenia and Thrombosis Syndrome (HIT/HITTS) PatientsCompletedNCT00759083Phase 4
2Evaluation of Argatroban Injection in Pediatric Patients Requiring Anticoagulant Alternatives to HeparinCompletedNCT00039858Phase 4
3Safety Study of Desirudin, an Anticoagulant for the Prophylaxis of ThrombosisCompletedNCT00913133Phase 4
4Venous Thromboembolic Prophylaxis After Trauma: Three Times a Day Unfractionated Heparin Versus Twice a Day EnoxaparinCompletedNCT01729559Phase 4
5Study to Evaluate the Mortality Reduction of Enoxaparin in Hospitalized Acutely Ill Medical Receiving EnoxaparinCompletedNCT00622648Phase 4
6EXCLAIM:Extended Prophylaxis for Venous ThromboEmbolism (VTE) in Acutely Ill Medical Patients With Prolonged ImmobilizationCompletedNCT00077753Phase 4
7Nadroparin for the Initial Treatment of Pulmonary ThromboembolismCompletedNCT00796692Phase 4
8Impact of Heparin on the Need for Mechanical Ventilation in NeonatesRecruitingNCT00196469Phase 4
9Efficacy and Safety of Heparin-coated Surface-treated Polyacrylonitrile Membrane Hemofilter in Critical Ill CRRT PatientsRecruitingNCT02355873Phase 4
10The HIT-TRAP TrialActive, not recruitingNCT00196417Phase 4
11A Comparative Sudy Comparing Argatroban® IV vs Desirudin SC for Suspected HIT With or Without Thrombosis SyndromeTerminatedNCT00787332Phase 4
12Argatroban Versus Lepirudin in Critically Ill PatientsTerminatedNCT00798525Phase 4
13Significance of Antibodies to Heparin/Platelet Factor 4 Complex in Vein Graft Patency and Potential Role of Argatroban for Prevention of Vein Graft OcclusionTerminatedNCT01246011Phase 4
14Fondaparinux in Patients With Acute Heparin-Induced Thrombocytopenia (HIT)WithdrawnNCT00603824Phase 4
15Efficacy and Safety Study of Argatroban to Treat Heparin-Induced ThrombocytopeniaCompletedNCT00198588Phase 3
16Anticoagulant Therapy With Bivalirudin in the Performance of Percutaneous Coronary Intervention in Patients With Heparin-Induced Thrombocytopenia (AT BAT, First Inning)CompletedNCT00043940Phase 3
17Angiomax in Patients With HIT/HITTS Type II Undergoing CPBCompletedNCT00079508Phase 3
18Study Comparing Desirudin With Heparin to Prevent Vein Clots After Heart and Lung SurgeryCompletedNCT00329433Phase 2, Phase 3
19PROphylaxis for ThromboEmbolism in Critical Care Trial (PROTECT)CompletedNCT00182143Phase 3
20PROSPER: PostpaRtum PrOphylaxiS for PE Randomized Control Trial PilotCompletedNCT01274637Phase 3
21Heparin 100U/L for Prevention of PVC ComplicationsCompletedNCT01131754Phase 3
22The Use of Fondaparinux in Preventing Thromboembolism in High Risk Trauma PatientsCompletedNCT00531843Phase 2, Phase 3
23A Safety and Efficacy Study of BCD-080 Compared to Clexan for Deep Vein Thrombosis Prophylaxis at Orthopedic SurgeriesRecruitingNCT02368314Phase 3
24Angiomax in Patients With HIT/HITTS Type II Undergoing Off-Pump Coronary Artery Bypass Grafting (CABG) (CHOOSE)Active, not recruitingNCT00073580Phase 3
25Fondaparinux to Prevent Thrombotic Complications and Graft Failure in Patients Undergoing Coronary Artery Bypass Graft Surgery: The Fonda CABG StudyNot yet recruitingNCT00474591Phase 3
26Rivaroxaban for Treatment of Patients With Suspected or Confirmed Heparin-Induced ThrombocytopeniaTerminatedNCT01598168Phase 3
27Clinical Management of Argatroban in Patients With Heparin Induced Thrombocytopenia Type IICompletedNCT00861692Phase 2
28ODiXahip - a Phase IIa Dose Escalating Proof of Principle TrialCompletedNCT00839826Phase 2
29Aneurysmal Subarachnoid Hemorrhage Trial RandOmizing HeparinRecruitingNCT02501434Phase 2
30Thoracic Surgery Extended Low-Molecular Weight Heparin VTE Prophylaxis--Pilot TrialRecruitingNCT02334007Phase 1, Phase 2
31Fondaparinux for the Treatment of Heparin-Induced Thrombocytopenia (HIT)TerminatedNCT00673439Phase 2
32Heparin-Induced Thrombocytopenia Score Card StudyCompletedNCT00489437Phase 1
33Pilot Dose Finding and Pharmacokinetic Study of Fondaparinux in Children With ThrombosisCompletedNCT00412464Phase 1
34Rapid Diagnosis of Heparin-Induced Thrombocytopenia in Surgical Critically Ill PatientsCompletedNCT02790567
35Heparin-induced Thrombocytopenia (HIT II) in Liver Transplant RecipientsCompletedNCT01654848
36Heparin-Induced Thrombocytopenia: Development and Validation of a Predictive ClinicalCompletedNCT00748839
37Heparin-Induced Thrombocytopenia RegistryCompletedNCT00456326
38Heparin Induced Thrombocytopenia: PharmacoeconomicsCompletedNCT00456001
39Heparin-Induced Thrombocytopenia - Retrospective Analysis of Data on Incidence and Outcomes StudyCompletedNCT01178333
40Retrospective Registry of Patients With Acute Heparin-induced Thrombocytopenia Type IICompletedNCT01304238
41Heparin Antibodies in Intensive Care Unit Patients (HAICU)CompletedNCT00283322
42Retrospective Study of Patients Who Were Treated With Fondaparinux Pre-, Peri- and/or Postpartum for Prophylaxis or Treatment of Venous ThromboembolismCompletedNCT01004939
43Identification of Donors of CD36-Deficient Platelets Among Japanese Individuals on the NIH CampusCompletedNCT00015639
44Effectiveness And Safety Of Dalteparin In Patients With Acute Coronary Syndromes Without ST Elevations In Clinical PracticeCompletedNCT00922766
45Pharmacogenomics of Heparin-Induced ThrombocytopeniaRecruitingNCT02717039
46Immunogenetics of Heparin-Induced Thrombocytopenia: Aim 2RecruitingNCT02526485
47Generation of Heparin-induced Thrombocytopenia (HIT)-Antibodies Without Prior Heparin ExposureRecruitingNCT01102790
48Incidence and Nature of Heparin-induced Skin Lesions in Medical PatientsRecruitingNCT00510432
49Study on the Incidence of Early Deep Vein Thrombosis After Peripherally Inserted Central Catheter InsertionRecruitingNCT02752984
50A Study on the Prevalence of Heparin-Induced Thrombocytopenia in Cardiovascular PatientsActive, not recruitingNCT00198575

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Genetic Tests for Heparin-Induced Thrombocytopenia

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Anatomical Context for Heparin-Induced Thrombocytopenia

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MalaCards organs/tissues related to Heparin-Induced Thrombocytopenia:

34
Testes, Heart, Liver, Skin, Lung, Monocytes, Endothelial

Animal Models for Heparin-Induced Thrombocytopenia or affiliated genes

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MGI Mouse Phenotypes related to Heparin-Induced Thrombocytopenia:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053857.6CD40LG, F10, F3, F5, SERPINC1
2MP:00107686.8CD40LG, F10, F3, F5, FCGR2A, SERPINC1

Publications for Heparin-Induced Thrombocytopenia

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Articles related to Heparin-Induced Thrombocytopenia:

(show top 50)    (show all 776)
idTitleAuthorsYear
1
Massive Pulmonary Embolism in a Patient with Heparin Induced Thrombocytopenia: Successful Treatment with Dabigatran. (27026768)
2016
2
Successful intraprocedural anticoagulation with bivalirudin during pulmonary vein isolation in a patient with known heparin-induced thrombocytopenia type II. (27092199)
2016
3
Perioperative use of iloprost in cardiac surgery patients diagnosed with heparin-induced thrombocytopenia (HIT) reactive antibodies or with true HIT (HIT reactive antibodies plus thrombocytopenia): An eleven year experience. (25808486)
2015
4
Transfemoral Transcatheter Aortic Valve Replacement in a Patient With Heparin-Induced Thrombocytopenia: Intraoperative Anticoagulation Management With Bivalirudin (Angiomax). (25604599)
2015
5
Heparin-Induced Thrombocytopenia. (26535527)
2015
6
Successful use of a bivalirudin treatment protocol to prevent extracorporeal thrombosis in ambulatory hemodialysis patients with heparin-induced thrombocytopenia. (26501237)
2015
7
Catastrophic antiphospholipid syndrome and heparin-induced thrombocytopenia presenting with adrenal insufficiency caused by bilateral hemorrhagic adrenal infarction during sepsis. (24709482)
2014
8
The frequency of heparin-induced thrombocytopenia in Taiwanese patients undergoing cardiopulmonary bypass surgery. (24331583)
2013
9
Clinical and Laboratory Diagnosis of Heparin-Induced Thrombocytopenia: An Integrated Approach. (24363239)
2013
10
Heparin-induced thrombocytopenia in Chinese patients: 240 patients study in one center. (24133900)
2013
11
A modified technique for implantation of the HeartWarea8c left ventricular assist device when using bivalirudin anticoagulation in patients with acute heparin-induced thrombocytopenia. (23628649)
2013
12
Murine monoclonal antibody to platelet factor 4/heparin complexes as a potential reference standard for platelet activation assays in heparin-induced thrombocytopenia. (22826445)
2013
13
Hemodialysis-associated acute systemic reactions and heparin-induced thrombocytopenia. (22127211)
2012
14
Left ventricular assist device, heparin-induced thrombocytopenia, and thrombus formation. (22186463)
2012
15
Treatment outcomes of heparin-induced thrombocytopenia in subarachnoid hemorrhage patients: a 4-year, retrospective single-center review. (22692920)
2012
16
Pituitary metastasis presenting as ischemic pituitary apoplexy following heparin-induced thrombocytopenia. (23129546)
2012
17
Evaluating heparin-induced thrombocytopenia: the old and the new. (22422328)
2012
18
The identification and management of heparin-induced thrombocytopenia in the vascular patient. (22188737)
2012
19
A clinical-laboratory algorithm incorporating optical density value to predict heparin-induced thrombocytopenia. (21264443)
2011
20
Heparin-induced thrombocytopenia and the utility of the 4Ts score in the Intensive Care Unit. (21255001)
2011
21
Evaluation of a standardized protocol using lepirudin or argatroban for heparin-induced thrombocytopenia. (21902659)
2011
22
Use of fondaparinux in a pregnant woman with pulmonary embolism and heparin-induced thrombocytopenia. (21525816)
2011
23
A rare and undesirable complication of heparin-induced thrombocytopenia: acute massive pulmonary embolism. (20699250)
2011
24
Prospective multicentre cohort study of heparin-induced thrombocytopenia in acute ischaemic stroke patients. (21671895)
2011
25
Fondaparinux in acute heparin-induced thrombocytopenia: a case series. (21883881)
2011
26
Heparin-induced thrombocytopenia in surgical patients. (20103065)
2010
27
Catastrophic rapid onset heparin-induced thrombocytopenia--victim of our own success. (20306898)
2010
28
Fondaparinux (Arixtra(R)), a safe alternative for the treatment of patients with heparin-induced thrombocytopenia? (21507819)
2010
29
Contribution of platelet microparticles generation assay to the diagnosis of type II heparin-induced thrombocytopenia. (20390228)
2010
30
Heparin-induced thrombocytopenia type II with thrombosis in an intensive care patient: therapy management using the direct thrombin inhibitor argatroban]. (19795099)
2009
31
Dosing lepirudin in patients with heparin-induced thrombocytopenia and normal or impaired renal function: a single-center experience with 68 patients. (19059879)
2009
32
A clinical-laboratory approach contributing to a rapid and reliable diagnosis of heparin-induced thrombocytopenia: An update. (19632705)
2009
33
Cerebral infarction associated with heparin-induced thrombocytopenia in a patient with encephalitis. (19122360)
2009
34
Hirudin for management of heparin-induced thrombocytopenia type II in a patient with biventricular assist device support. (20037107)
2009
35
Bioline heparin-coated ECMO with bivalirudin anticoagulation in a patient with acute heparin-induced thrombocytopenia: the immune reaction appeared to continue unabated. (19654158)
2009
36
Heparin-induced thrombocytopenia successfully treated with fondaparinux. (19432027)
2009
37
Serologic results in >1000 patients with suspected heparin-induced thrombocytopenia. (17895512)
2008
38
Heparin-induced thrombocytopenia: diagnosis and management. (18544310)
2008
39
Heparin-dependent antibodies and thrombosis without heparin-induced thrombocytopenia. (18957000)
2008
40
Heparin induced thrombocytopenia in patients with ventricular assistance device bridge-to-transplantation. A case series. (19092745)
2008
41
Spontaneous superior sagittal sinus thrombosis secondary to type II heparin-induced thrombocytopenia presenting as an acute subarachnoid hemorrhage. (17582771)
2007
42
Argatroban therapy in women with heparin-induced thrombocytopenia. (17678460)
2007
43
Incidence and clinical significance of anti-PF4/heparin antibodies of the IgG, IgM, and IgA class in 755 consecutive patient samples referred for diagnostic testing for heparin-induced thrombocytopenia. (16466367)
2006
44
Lepirudin for prophylaxis of thrombosis in patients with acute isolated heparin-induced thrombocytopenia: an analysis of 3 prospective studies. (15280202)
2004
45
Extensive life-threatening thrombosis in a patient with heparin-induced thrombocytopenia and factor V Leiden mutation. (11532640)
2001
46
Factor V Leiden and thrombotic complications in heparin-induced thrombocytopenia. (9459322)
1998
47
Characterization of the humoral immune response in heparin-induced thrombocytopenia. (9067497)
1997
48
Heparin-induced thrombocytopenia as an autoimmune disease--idiotypic evidence for the role of anti-heparin/PF4 autoantibodies. (9347871)
1997
49
Platelet binding of IgG from patients with heparin-induced thrombocytopenia. (8621980)
1996
50
Heparin-induced thrombocytopenia and thrombosis. (9372019)
1995

Variations for Heparin-Induced Thrombocytopenia

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Expression for genes affiliated with Heparin-Induced Thrombocytopenia

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Search GEO for disease gene expression data for Heparin-Induced Thrombocytopenia.

Pathways for genes affiliated with Heparin-Induced Thrombocytopenia

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GO Terms for genes affiliated with Heparin-Induced Thrombocytopenia

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Cellular components related to Heparin-Induced Thrombocytopenia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1intrinsic component of external side of plasma membraneGO:003123310.2F10, F3
2extracellular spaceGO:00056158.4CD40LG, F3, F5, SERPINC1
3plasma membraneGO:00058867.1CD40LG, F10, F3, F5, FCGR2A, SERPINC1

Biological processes related to Heparin-Induced Thrombocytopenia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1blood coagulation, extrinsic pathwayGO:00075989.9F10, F3
2positive regulation of protein kinase B signalingGO:00518979.6F10, F3
3blood coagulationGO:00075968.5F10, F3, F5, SERPINC1

Molecular functions related to Heparin-Induced Thrombocytopenia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protease bindingGO:00020209.6F3, SERPINC1
2phospholipid bindingGO:00055439.3F10, F3
3serine-type endopeptidase activityGO:00042528.6F10, F3, F5

Sources for Heparin-Induced Thrombocytopenia

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2CDC
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10DGIdb
15ExPASy
16FDA
17FMA
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28ICD10
29ICD10 via Orphanet
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31IUPHAR
32KEGG
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44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet