MCID: HPT006
MIFTS: 33

Hepatic Angiomyolipoma malady

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Hepatic Angiomyolipoma

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Aliases & Descriptions for Hepatic Angiomyolipoma:

Name: Hepatic Angiomyolipoma 11 13 67

Classifications:



External Ids:

Disease Ontology11 DOID:3317
NCIt44 C27485

Summaries for Hepatic Angiomyolipoma

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MalaCards based summary: Hepatic Angiomyolipoma is related to hepatocellular carcinoma and hepatitis. An important gene associated with Hepatic Angiomyolipoma is AFP (Alpha Fetoprotein), and among its related pathways are Regulation of Telomerase and LKB1 signaling events. Affiliated tissues include liver, testes and small intestine, and related mouse phenotypes are liver/biliary system and neoplasm.

Related Diseases for Hepatic Angiomyolipoma

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Diseases related to Hepatic Angiomyolipoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 58)
idRelated DiseaseScoreTop Affiliating Genes
1hepatocellular carcinoma28.2AFP, KIT, MTOR, MYC, RB1
2hepatitis10.7
3angiomyolipoma10.7
4peritonitis10.2AFP, KIT
5prostate small cell carcinoma10.2AFP, KIT
6sphenoidal sinus cancer10.2AFP, KIT
7localized pulmonary fibrosis10.2AFP, KIT
8nutritional deficiency disease10.2AFP, KIT
9vibratory urticaria10.2AFP, KIT
10nephrogenic adenofibroma10.2AFP, KIT
11posteroinferior myocardial infarction10.2AFP, KIT
12breast squamous cell carcinoma10.2AFP, KIT
13brain sarcoma10.1AFP, KIT
14tenosynovitis of foot and ankle10.1KIT, MTOR
15malignant epithelial mesothelioma10.1AFP, MYC
16multiple spinal canal and spinal cord meningioma10.1AFP, KIT
17epithelioid type angiomyolipoma10.1KIT, MTOR
18gallbladder angiosarcoma10.1KIT, MYC
19small cell sarcoma10.1AFP, MYC
20hemochromatosis type 210.1MTOR, MYC
21macular retinal edema10.1AFP, KIT
22cholesteatoma of external ear10.1KIT, MYC
23neurodermatitis10.1AFP, KIT
24familial mitral valve prolapse10.0KIT, MYC
25localized osteosarcoma10.0KIT, MYC
26chikungunya10.0KIT, MYC
27spinal cord primitive neuroectodermal neoplasm10.0AFP, MYC
282-hydroxyethyl methacrylate sensitization9.9AFP, RB1
29multidrug-resistant tuberculosis9.9KIT, RB1
30hemolytic anemia9.9KIT, MYC
31plasmacytoma9.8AFP, MYC
32organ system benign neoplasm9.8KIT, MYC
33desmoplastic infantile astrocytoma9.8KIT, RB1
34lymphangioleiomyomatosis9.8
35hemangioma9.8
36gliomatosis peritonei9.7MTOR, MYC
37bilateral retinoblastoma9.7MYC, RB1
38brown-vialetto-van laere syndrome9.7AFP, KIT, MYC
39gallbladder papillomatosis9.7AFP, KIT, MYC
40pharynx cancer9.7MYC, RB1
41ascending colon cancer9.7MYC, RB1
42neurofibromatosis, type 29.7
43arteriovenous fistula9.7
44ulcerative colitis9.7
45colitis9.7
46disseminated intravascular coagulation9.7
47rhabdomyosarcoma9.7
48cavernous hemangioma9.7
49pancreatitis9.7
50giant hemangioma9.7

Graphical network of the top 20 diseases related to Hepatic Angiomyolipoma:



Diseases related to hepatic angiomyolipoma

Symptoms for Hepatic Angiomyolipoma

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Drugs & Therapeutics for Hepatic Angiomyolipoma

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Interventional clinical trials:

idNameStatusNCT IDPhase
1A Phase II Study of Orally Administered BEZ235 Monotherapy in Patients With Metastatic or Unresectable Malignant PEComaWithdrawnNCT01690871Phase 2

Search NIH Clinical Center for Hepatic Angiomyolipoma

Genetic Tests for Hepatic Angiomyolipoma

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Anatomical Context for Hepatic Angiomyolipoma

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MalaCards organs/tissues related to Hepatic Angiomyolipoma:

35
Liver, Testes, Small intestine

Animal Models for Hepatic Angiomyolipoma or affiliated genes

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MGI Mouse Phenotypes related to Hepatic Angiomyolipoma:

40 (show all 11)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053708.9AFP, KIT, MYC, RB1
2MP:00020068.8AFP, KIT, MYC, RB1
3MP:00053808.8KIT, MTOR, MYC, RB1
4MP:00053698.8KIT, MTOR, MYC, RB1
5MP:00030128.7KIT, MTOR, MYC, RB1
6MP:00028738.6KIT, MTOR, MYC, RB1
7MP:00011868.5KIT, MYC, RB1
8MP:00053868.4AFP, KIT, MTOR, MYC, RB1
9MP:00053798.4AFP, KIT, MTOR, MYC, RB1
10MP:00053768.3AFP, KIT, MTOR, MYC, RB1

Publications for Hepatic Angiomyolipoma

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Articles related to Hepatic Angiomyolipoma:

(show top 50)    (show all 131)
idTitleAuthorsYear
1
Comparison of CT and contrast-enhanced ultrasound findings in hepatic angiomyolipoma with pathological correlations. (26867906)
2016
2
Hepatic angiomyolipoma: differential diagnosis from other liver tumors in a special reference to vascular imaging - importance of early drainage vein. (26943379)
2015
3
Visualizing Central Vessels of Hepatic Angiomyolipoma Devoid of Fat Using a 2D Multi-Breath-Hold Susceptibility-Weighted Imaging. (26114004)
2015
4
Liver transplantation for recurrent posthepatectomy malignant hepatic angiomyolipoma: A case report. (25834347)
2015
5
Hepatic angiomyolipoma mimicking hepatocellular carcinoma: magnetic resonance imaging and clinical pathological characteristics in 9 cases. (25803731)
2015
6
Diagnosis of Hepatic Angiomyolipoma by Combination of Baseline and Contrast-Enhanced Ultrasound--A Prospective Study in Non-Cirrhotic Patients. (26147859)
2015
7
Myomatous hepatic angiomyolipoma: imaging findings in 14 cases with radiological-pathological correlation and review of the literature. (24670055)
2014
8
Hepatic angiomyolipoma: what management? (25073214)
2014
9
Spontaneous rupture of a hepatic angiomyolipoma: Report of a case. (26184024)
2014
10
Hepatic angiomyolipoma growing to cause epigastric discomfort: a case report. (26185889)
2014
11
Immunohistochemical character of hepatic angiomyolipoma: for its management. (23864864)
2013
12
Hepatic angiomyolipoma and neurofibromatosis type 2: a novel association. (24314304)
2013
13
Hepatic angiomyolipoma: CT and MR imaging findings with clinical-pathologic comparison. (22996326)
2013
14
Hepatic angiomyolipoma: a case report with diagnostic challenge. (24152510)
2013
15
Hepatic angiomyolipoma: clinical, imaging and pathological features in 178 cases. (23292871)
2013
16
Is surgery necessary for patients with hepatic angiomyolipoma? Retrospective analysis from eight Chinese cases. (23731017)
2013
17
Hepatic angiomyolipoma with minimal fat, mimicking hepatocellular carcinoma. (23091816)
2012
18
Development of hepatic angiomyolipoma accompanied with focal nodular hyperplasia long after treatment of pelvic rhabdomyosarcoma. (21683235)
2011
19
Angiogenesis and lymphangiogenesis in sporadic hepatic angiomyolipoma. (21665376)
2011
20
F-18 FDG PET/CT findings in two patients with hepatic angiomyolipoma with and without intratumoral hemorrhage. (20026966)
2010
21
Hepatic angiomyolipoma: a case report. (20518257)
2010
22
Hepatic angiomyolipoma: a clinical experience in diagnosis and treatment. (20165978)
2010
23
Hepatic Angiomyolipoma with Minimal Intratumoral Fat Content. (21103249)
2009
24
Clinical challenges and images in GI. Diagnosis: Hepatic angiomyolipoma mimicking hepatocellular carcinoma. (19254682)
2009
25
Wunderlich's syndrome with hepatic angiomyolipoma in tuberous sclerosis. (18626151)
2008
26
Hepatic angiomyolipoma. (18834230)
2008
27
Management of hepatic angiomyolipoma. (17436129)
2007
28
Hepatic angiomyolipoma with trace amounts of fat: a case report and literature review. (17071805)
2006
29
Hepatic angiomyolipoma demonstrating similar imaging characteristics as hepatocellular carcinoma: one case report. (16463691)
2005
30
Contrast-enhanced ultrasonography in hepatic angiomyolipoma. (15914690)
2005
31
Hepatic angiomyolipoma and hepatic stellate cells share a similar gene expression profile. (15891994)
2005
32
Aggressive hepatic angiomyolipoma in a child. (15770828)
2005
33
A solitary hepatic lesion: MRI-pathological correlation of an hepatic angiomyolipoma (2004:4b). (15221270)
2004
34
Hepatic angiomyolipoma: demonstration by out of phase MRI. (12427439)
2002
35
Hepatic angiomyolipoma: report of 8 cases and review of literature. (17585451)
2002
36
Fine-needle aspiration cytology of hepatic angiomyolipoma: case report with histological, immunohistochemical and electron microscopic findings. (17261940)
2001
37
Hepatic angiomyolipoma-misdiagnosis as hepatocellular carcinoma: A report of 14 cases. (11819659)
2000
38
Hepatic angiomyolipoma: a rarely described tumor. (11059879)
2000
39
Nuclear pseudoinclusions in fine-needle aspiration cytology of hepatic angiomyolipoma: case report. (10820535)
2000
40
Hepatic angiomyolipoma: a clinicopathologic study of 30 cases and delineation of unusual morphologic variants. (9888702)
1999
41
Hepatic angiomyolipoma with 'oncocyte-like' features. (9870158)
1998
42
Spontaneous rupture of a hepatic angiomyolipoma: CT findings and literature review. (9087353)
1997
43
Hepatic angiomyolipoma: two case reports of caudate-based lesions and review of the literature. (9377758)
1997
44
Hepatic angiomyolipoma with minimal fat content: MR demonstration. (8897374)
1996
45
Immunohistochemical study of hepatic angiomyolipoma. (10846546)
1996
46
Hepatic angiomyolipoma. (7880772)
1994
47
Hepatic angiomyolipomas with a deceptive trabecular pattern and HMB-45 reactivity. (1334941)
1992
48
An electron microscopic study of hepatic angiomyolipoma. (2694755)
1989
49
Giant hepatic angiomyolipoma simulating focal nodular hyperplasia. (3404779)
1988
50
Hepatic angiomyolipoma. A case report with review of the literature. (3064546)
1988

Variations for Hepatic Angiomyolipoma

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Expression for genes affiliated with Hepatic Angiomyolipoma

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Search GEO for disease gene expression data for Hepatic Angiomyolipoma.

Pathways for genes affiliated with Hepatic Angiomyolipoma

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GO Terms for genes affiliated with Hepatic Angiomyolipoma

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Cellular components related to Hepatic Angiomyolipoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1PML bodyGO:00166059.1MTOR, RB1

Biological processes related to Hepatic Angiomyolipoma according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1energy reserve metabolic processGO:00061129.9MTOR, MYC
2positive regulation of glial cell proliferationGO:00602529.9MTOR, MYC
3phosphatidylinositol-mediated signalingGO:00480159.8KIT, MTOR
4positive regulation of smooth muscle cell proliferationGO:00486619.7MTOR, MYC
5visual learningGO:00085429.4KIT, MTOR
6digestive tract developmentGO:00485659.4KIT, RB1
7regulation of mitotic cell cycleGO:00073469.4MYC, RB1
8ovarian follicle developmentGO:00015419.3KIT, MYC
9chromatin remodelingGO:00063389.1MYC, RB1
10cell cycle arrestGO:00070508.7MTOR, MYC, RB1

Molecular functions related to Hepatic Angiomyolipoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1phosphoprotein bindingGO:00512199.1MTOR, RB1

Sources for Hepatic Angiomyolipoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet