MCID: HPT006
MIFTS: 33

Hepatic Angiomyolipoma malady

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Hepatic Angiomyolipoma

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Aliases & Descriptions for Hepatic Angiomyolipoma:

Name: Hepatic Angiomyolipoma 11 13 66

Classifications:



External Ids:

Disease Ontology11 DOID:3317
NCIt43 C27485

Summaries for Hepatic Angiomyolipoma

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MalaCards based summary: Hepatic Angiomyolipoma is related to hepatocellular carcinoma and hepatitis. An important gene associated with Hepatic Angiomyolipoma is AFP (Alpha Fetoprotein), and among its related pathways are IL2 signaling events mediated by PI3K and TSLP Signaling Pathway. Affiliated tissues include liver, testes and small intestine, and related mouse phenotypes are pigmentation and adipose tissue.

Related Diseases for Hepatic Angiomyolipoma

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Diseases related to Hepatic Angiomyolipoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 59)
idRelated DiseaseScoreTop Affiliating Genes
1hepatocellular carcinoma28.3AFP, KIT, MTOR, MYC, RB1
2hepatitis10.8
3angiomyolipoma10.8
4hemochromatosis type 210.3MTOR, MYC
5malignant epithelial mesothelioma10.2AFP, MYC
6small cell sarcoma10.2AFP, MYC
7tuberous sclerosis10.2
82-hydroxyethyl methacrylate sensitization10.1AFP, RB1
9tenosynovitis of foot and ankle10.0KIT, MTOR
10spinal cord primitive neuroectodermal neoplasm10.0AFP, MYC
11peritonitis10.0AFP, KIT
12prostate small cell carcinoma10.0AFP, KIT
13sphenoidal sinus cancer10.0AFP, KIT
14localized pulmonary fibrosis10.0AFP, KIT
15nutritional deficiency disease10.0AFP, KIT
16epithelioid type angiomyolipoma10.0KIT, MTOR
17bilateral retinoblastoma9.9MYC, RB1
18vibratory urticaria9.9AFP, KIT
19nephrogenic adenofibroma9.9AFP, KIT
20posteroinferior myocardial infarction9.9AFP, KIT
21pharynx cancer9.9MYC, RB1
22gallbladder angiosarcoma9.9KIT, MYC
23breast squamous cell carcinoma9.9AFP, KIT
24lymphangioleiomyomatosis9.9
25hemangioma9.9
26ascending colon cancer9.9MYC, RB1
27cholesteatoma of external ear9.9KIT, MYC
28brain sarcoma9.9AFP, KIT
29multiple spinal canal and spinal cord meningioma9.8AFP, KIT
30familial mitral valve prolapse9.8KIT, MYC
31localized osteosarcoma9.8KIT, MYC
32chikungunya9.8KIT, MYC
33stenosis of lacrimal sac9.8MYC, RB1
34neurofibromatosis, type 29.8
35arteriovenous fistula9.8
36ulcerative colitis9.8
37colitis9.8
38disseminated intravascular coagulation9.8
39melanoma9.8
40rhabdomyosarcoma9.8
41cavernous hemangioma9.8
42pancreatitis9.8
43giant hemangioma9.8
44neurofibromatosis9.8
45multidrug-resistant tuberculosis9.8KIT, RB1
46macular retinal edema9.8AFP, KIT
47neurodermatitis9.7AFP, KIT
48gliosarcoma9.7MTOR, MYC, RB1
49esophagus lymphoma9.7MYC, RB1
50desmoplastic infantile astrocytoma9.7KIT, RB1

Graphical network of the top 20 diseases related to Hepatic Angiomyolipoma:



Diseases related to hepatic angiomyolipoma

Symptoms for Hepatic Angiomyolipoma

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Drugs & Therapeutics for Hepatic Angiomyolipoma

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Interventional clinical trials:

idNameStatusNCT IDPhase
1A Phase II Study of Orally Administered BEZ235 Monotherapy in Patients With Metastatic or Unresectable Malignant PEComaWithdrawnNCT01690871Phase 2

Search NIH Clinical Center for Hepatic Angiomyolipoma

Genetic Tests for Hepatic Angiomyolipoma

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Anatomical Context for Hepatic Angiomyolipoma

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MalaCards organs/tissues related to Hepatic Angiomyolipoma:

34
Liver, Testes, Small intestine

Animal Models for Hepatic Angiomyolipoma or affiliated genes

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MGI Mouse Phenotypes related to Hepatic Angiomyolipoma:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011868.9KIT, MYC, RB1
2MP:00053758.5CRBN, MTOR, MYC, RB1
3MP:00020068.4AFP, KIT, MYC, RB1
4MP:00053698.3KIT, MTOR, MYC, RB1
5MP:00030128.3KIT, MTOR, MYC, RB1
6MP:00053708.0AFP, CRBN, KIT, MYC, RB1
7MP:00053797.5AFP, KIT, MTOR, MYC, RB1
8MP:00053767.1AFP, CRBN, KIT, MTOR, MYC, RB1
9MP:00053866.8AFP, CRBN, KIT, MTOR, MYC, RB1

Publications for Hepatic Angiomyolipoma

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Articles related to Hepatic Angiomyolipoma:

(show top 50)    (show all 130)
idTitleAuthorsYear
1
Comparison of CT and contrast-enhanced ultrasound findings in hepatic angiomyolipoma with pathological correlations. (26867906)
2016
2
Hepatic angiomyolipoma: differential diagnosis from other liver tumors in a special reference to vascular imaging - importance of early drainage vein. (26943379)
2015
3
Visualizing Central Vessels of Hepatic Angiomyolipoma Devoid of Fat Using a 2D Multi-Breath-Hold Susceptibility-Weighted Imaging. (26114004)
2015
4
Liver transplantation for recurrent posthepatectomy malignant hepatic angiomyolipoma: A case report. (25834347)
2015
5
Hepatic angiomyolipoma mimicking hepatocellular carcinoma: magnetic resonance imaging and clinical pathological characteristics in 9 cases. (25803731)
2015
6
Diagnosis of Hepatic Angiomyolipoma by Combination of Baseline and Contrast-Enhanced Ultrasound--A Prospective Study in Non-Cirrhotic Patients. (26147859)
2015
7
Myomatous hepatic angiomyolipoma: imaging findings in 14 cases with radiological-pathological correlation and review of the literature. (24670055)
2014
8
Hepatic angiomyolipoma: what management? (25073214)
2014
9
Spontaneous rupture of a hepatic angiomyolipoma: Report of a case. (26184024)
2014
10
Hepatic angiomyolipoma growing to cause epigastric discomfort: a case report. (26185889)
2014
11
Immunohistochemical character of hepatic angiomyolipoma: for its management. (23864864)
2013
12
Hepatic angiomyolipoma and neurofibromatosis type 2: a novel association. (24314304)
2013
13
Hepatic angiomyolipoma: CT and MR imaging findings with clinical-pathologic comparison. (22996326)
2013
14
Hepatic angiomyolipoma: a case report with diagnostic challenge. (24152510)
2013
15
Hepatic angiomyolipoma: clinical, imaging and pathological features in 178 cases. (23292871)
2013
16
Is surgery necessary for patients with hepatic angiomyolipoma? Retrospective analysis from eight Chinese cases. (23731017)
2013
17
Hepatic angiomyolipoma with minimal fat, mimicking hepatocellular carcinoma. (23091816)
2012
18
Development of hepatic angiomyolipoma accompanied with focal nodular hyperplasia long after treatment of pelvic rhabdomyosarcoma. (21683235)
2011
19
Angiogenesis and lymphangiogenesis in sporadic hepatic angiomyolipoma. (21665376)
2011
20
F-18 FDG PET/CT findings in two patients with hepatic angiomyolipoma with and without intratumoral hemorrhage. (20026966)
2010
21
Hepatic angiomyolipoma: a case report. (20518257)
2010
22
Hepatic angiomyolipoma: a clinical experience in diagnosis and treatment. (20165978)
2010
23
Hepatic Angiomyolipoma with Minimal Intratumoral Fat Content. (21103249)
2009
24
Clinical challenges and images in GI. Diagnosis: Hepatic angiomyolipoma mimicking hepatocellular carcinoma. (19254682)
2009
25
Wunderlich's syndrome with hepatic angiomyolipoma in tuberous sclerosis. (18626151)
2008
26
Hepatic angiomyolipoma. (18834230)
2008
27
Management of hepatic angiomyolipoma. (17436129)
2007
28
Hepatic angiomyolipoma with trace amounts of fat: a case report and literature review. (17071805)
2006
29
Hepatic angiomyolipoma demonstrating similar imaging characteristics as hepatocellular carcinoma: one case report. (16463691)
2005
30
Contrast-enhanced ultrasonography in hepatic angiomyolipoma. (15914690)
2005
31
Hepatic angiomyolipoma and hepatic stellate cells share a similar gene expression profile. (15891994)
2005
32
Aggressive hepatic angiomyolipoma in a child. (15770828)
2005
33
A solitary hepatic lesion: MRI-pathological correlation of an hepatic angiomyolipoma (2004:4b). (15221270)
2004
34
Hepatic angiomyolipoma: demonstration by out of phase MRI. (12427439)
2002
35
Hepatic angiomyolipoma: report of 8 cases and review of literature. (17585451)
2002
36
Fine-needle aspiration cytology of hepatic angiomyolipoma: case report with histological, immunohistochemical and electron microscopic findings. (17261940)
2001
37
Hepatic angiomyolipoma-misdiagnosis as hepatocellular carcinoma: A report of 14 cases. (11819659)
2000
38
Hepatic angiomyolipoma: a rarely described tumor. (11059879)
2000
39
Nuclear pseudoinclusions in fine-needle aspiration cytology of hepatic angiomyolipoma: case report. (10820535)
2000
40
Hepatic angiomyolipoma: a clinicopathologic study of 30 cases and delineation of unusual morphologic variants. (9888702)
1999
41
Hepatic angiomyolipoma with 'oncocyte-like' features. (9870158)
1998
42
Spontaneous rupture of a hepatic angiomyolipoma: CT findings and literature review. (9087353)
1997
43
Hepatic angiomyolipoma: two case reports of caudate-based lesions and review of the literature. (9377758)
1997
44
Hepatic angiomyolipoma with minimal fat content: MR demonstration. (8897374)
1996
45
Immunohistochemical study of hepatic angiomyolipoma. (10846546)
1996
46
Hepatic angiomyolipoma. (7880772)
1994
47
Hepatic angiomyolipomas with a deceptive trabecular pattern and HMB-45 reactivity. (1334941)
1992
48
An electron microscopic study of hepatic angiomyolipoma. (2694755)
1989
49
Giant hepatic angiomyolipoma simulating focal nodular hyperplasia. (3404779)
1988
50
Hepatic angiomyolipoma. A case report with review of the literature. (3064546)
1988

Variations for Hepatic Angiomyolipoma

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Expression for genes affiliated with Hepatic Angiomyolipoma

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Search GEO for disease gene expression data for Hepatic Angiomyolipoma.

Pathways for genes affiliated with Hepatic Angiomyolipoma

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GO Terms for genes affiliated with Hepatic Angiomyolipoma

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Biological processes related to Hepatic Angiomyolipoma according to GeneCards Suite gene sharing:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1energy reserve metabolic processGO:000611210.1MTOR, MYC
2positive regulation of glial cell proliferationGO:006025210.0MTOR, MYC
3positive regulation of smooth muscle cell proliferationGO:00486619.9MTOR, MYC
4regulation of mitotic cell cycleGO:00073469.5MYC, RB1
5chromatin remodelingGO:00063389.4MYC, RB1
6digestive tract developmentGO:00485659.3KIT, RB1
7visual learningGO:00085429.2KIT, MTOR
8ovarian follicle developmentGO:00015419.1KIT, MYC
9cell cycle arrestGO:00070509.0MTOR, MYC, RB1

Molecular functions related to Hepatic Angiomyolipoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1phosphoprotein bindingGO:00512199.4MTOR, RB1

Sources for Hepatic Angiomyolipoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet