MCID: HPT006
MIFTS: 29

Hepatic Angiomyolipoma malady

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Hepatic Angiomyolipoma

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Aliases & Descriptions for Hepatic Angiomyolipoma:

Name: Hepatic Angiomyolipoma 10 12 65

Classifications:



External Ids:

Disease Ontology10 DOID:3317
NCIt42 C27485
UMLS65 C1333962

Summaries for Hepatic Angiomyolipoma

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MalaCards based summary: Hepatic Angiomyolipoma is related to gastrointestinal system cancer and adult epithelioid sarcoma. An important gene associated with Hepatic Angiomyolipoma is MTOR (Mechanistic Target Of Rapamycin), and among its related pathways is Central carbon metabolism in cancer. Affiliated tissues include bone, brain and lung, and related mouse phenotypes are endocrine/exocrine gland and adipose tissue.

Related Diseases for Hepatic Angiomyolipoma

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Diseases related to Hepatic Angiomyolipoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 129)
idRelated DiseaseScoreTop Affiliating Genes
1gastrointestinal system cancer10.0KIT, MTOR
2adult epithelioid sarcoma10.0AFP, KIT
3breast cancer10.0
4obesity10.0
5gastric cancer10.0
6adenoma10.0
7neuronitis10.0
8mediastinitis10.0
9headache10.0
10endotheliitis10.0
11ovarian cystic teratoma10.0AFP, KIT
12bartholin's gland small cell carcinoma10.0AFP, KIT
13mediastinal mesenchymal tumor10.0AFP, KIT
14seminal vesicle adenocarcinoma10.0AFP, KIT
15swayback10.0AFP, KIT
16hepatic angiomyolipoma10.0KIT, MTOR
17diffuse pulmonary fibrosis10.0AFP, KIT
18head and neck carcinoma10.0AFP, KIT
19focal cortical dysplasia, taylor balloon cell type10.0CTSK, MTOR
20testis seminoma10.0AFP, KIT
21atypical teratoid rhabdoid tumor10.0AFP, KIT
22geroderma osteodysplastica10.0AFP, KIT
23acantholytic squamous cell skin carcinoma10.0AFP, KIT
24embryonal carcinoma9.9AFP, KIT
25cervical alveolar soft part sarcoma9.9AFP, KIT
26colorectal cancer9.9
27myocardial infarction9.9
28melioidosis9.9
29asthma9.9
30attention deficit-hyperactivity disorder9.9
31pulmonary alveolar microlithiasis9.9
32ataxia-telangiectasia9.9
33mevalonic aciduria9.9
34retinoblastoma9.9
35trichotillomania9.9
36insulin-like growth factor i9.9
37acute myocardial infarction9.9
38alopecia9.9
39craniosynostosis9.9
40crohn's disease9.9
41diabetic neuropathy9.9
42hemangioma9.9
43lymphedema9.9
44polycystic ovary syndrome9.9
45retinitis pigmentosa9.9
46sinusitis9.9
47spinal muscular atrophy9.9
48usher syndrome9.9
49asphyxiating thoracic dystrophy9.9
50myeloma9.9

Graphical network of the top 20 diseases related to Hepatic Angiomyolipoma:



Diseases related to hepatic angiomyolipoma

Symptoms for Hepatic Angiomyolipoma

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Drugs & Therapeutics for Hepatic Angiomyolipoma

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Interventional clinical trials:

idNameStatusNCT IDPhase
1A Phase II Study of Orally Administered BEZ235 Monotherapy in Patients With Metastatic or Unresectable Malignant PEComaWithdrawnNCT01690871Phase 2

Search NIH Clinical Center for Hepatic Angiomyolipoma

Genetic Tests for Hepatic Angiomyolipoma

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Anatomical Context for Hepatic Angiomyolipoma

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MalaCards organs/tissues related to Hepatic Angiomyolipoma:

33
Bone, Brain, Lung, Endothelial, T cells, Prostate, Breast

Animal Models for Hepatic Angiomyolipoma or affiliated genes

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MGI Mouse Phenotypes related to Hepatic Angiomyolipoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053798.5AFP, CTSK, KIT, MTOR
2MP:00053758.4CRBN, CTSK, MTOR
3MP:00053767.5AFP, CRBN, CTSK, KIT, MTOR

Publications for Hepatic Angiomyolipoma

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Articles related to Hepatic Angiomyolipoma:

(show top 50)    (show all 126)
idTitleAuthorsYear
1
Managing the female patient with hereditary angioedema. (26978558)
2016
2
Intrahepatic cholestasis of pregnancy: maternal and fetal outcomes associated with elevated bile acid levels. (25818669)
2015
3
CD-163 correlated with symptoms (pain or discomfort) of prostatic inflammation. (26045748)
2015
4
Re: Cursiefen etA al.: Aganirsen antisense oligonucleotide eye drops inhibit keratitis-induced corneal neovascularization and reduce need for transplantation: the I-CAN study (Ophthalmology 2014;121:1683-92). (25919780)
2015
5
MEK inhibitor diminishes nasopharyngeal carcinoma (NPC) cell growth and NPC-induced osteoclastogenesis via modulating CCL2 and CXCL16 expressions. (26058873)
2015
6
let-7 miRNAs can act through notch to regulate human gliogenesis. (25316189)
2014
7
Update on neonatal hypoglycemia. (24275620)
2014
8
Osteonecrosis of the femoral head in SARS patients: seven years later. (23412187)
2013
9
Abnormalities in fronto-striatal connectivity within language networks relate to differences in grey-matter heterogeneity in Asperger syndrome. (24179823)
2013
10
Expression and relationship of proinflammatory chemokine RANTES/CCL5 and cytokine IL-1I^ in painful human intervertebral discs. (23660804)
2013
11
Omalizumab for the treatment of severe persistent allergic asthma in children aged 6-11 years. (21609649)
2011
12
A major role for HERG in determining frequency of reentry in neonatal rat ventricular myocyte monolayer. (20947828)
2010
13
89Zr-bevacizumab PET of early antiangiogenic tumor response to treatment with HSP90 inhibitor NVP-AUY922. (20395337)
2010
14
Severe rhabdomyolysis as a first symptom in Addison's disease. (19625758)
2010
15
A National Heart, Lung, and Blood Institute history and perspective on lymphangioleiomyomatosis. (20235882)
2010
16
Combinatorial peptide libraries facilitate development of multiple reaction monitoring assays for low-abundance proteins. (20070123)
2010
17
Neutrophil gelatinase-associated lipocalin (NGAL): a new marker of cyclosporine nephrotoxicity? (20072790)
2010
18
The frequency of Muir-Torre syndrome among Lynch syndrome families. (18270343)
2008
19
Computer-aided detection of ischemic lesions related to subcortical vascular dementia on magnetic resonance images. (18620118)
2008
20
Multicystic encephalomalacia in an uncomplicated twin pregnancy. (18400596)
2008
21
Interaction between cyclooxygenase (COX)-1- and COX-2-products modulates COX-2 expression in the late phase of acute inflammation. (17258197)
2007
22
Sclerosing epithelioid fibrosarcoma of the cecum: a radiation-associated tumor in a previously unreported site. (18081443)
2007
23
Fatty pain cures. (18096498)
2007
24
Trafficking of a secretory granule membrane protein is sensitive to copper. (17562710)
2007
25
Brief historical remarks as an introduction for the international symposium on taeniasis/cysticercosis and echinococcosis. (16337830)
2006
26
The dynamics of gene expression in human lung microvascular endothelial cells after stimulation with inflammatory cytokines. (15857163)
2006
27
Coagulation inhibitors in preeclamptic pregnant women. (14735372)
2005
28
Corticoids normalize leukocyte production of macrophage migration inhibitory factor in septic shock. (15593015)
2005
29
Prevention by 17beta-estradiol and progesterone of calcitonin gene-related peptide-induced elevation of skin temperature in castrated male rats. (15533515)
2004
30
Molecular genetics in the analysis of suicide. (12822741)
2003
31
CXCR4/CD184 immunoreactivity in T-cell non-Hodgkin lymphomas with an overall Th1- Th2+ immunophenotype. (12645345)
2003
32
Functional reconstitution of Ral-binding GTPase activating protein, RLIP76, in proteoliposomes catalyzing ATP-dependent transport of glutathione conjugate of 4-hydroxynonenal. (12422239)
2002
33
Peg3/Pw1 is involved in p53-mediated cell death pathway in brain ischemia/hypoxia. (11679586)
2002
34
Division of mitochondria requires a novel DMN1-interacting protein, Net2p. (11179417)
2001
35
A non-transmembrane form of Jagged-1 regulates the formation of matrix-dependent chord-like structures. (10679295)
2000
36
Differential role for Sp1/Sp3 transcription factors in the regulation of the promoter activity of multiple cyclin-dependent kinase inhibitor genes. (10649433)
2000
37
Case 21-1997: Paraneoplastic cerebellar degeneration and Hodgkin's disease. (9424575)
1998
38
A case of presumptive monosomy 21 re-diagnosed as unbalanced t(5p;21q) by FISH and review of literature. (9128939)
1997
39
The effects of neurotransmitter antagonists and glucose on luteinizing hormone secretion in growth-restricted wethers. (9231237)
1997
40
Methylation of estrogen and progesterone receptor gene 5' CpG islands correlates with lack of estrogen and progesterone receptor gene expression in breast tumors. (9816234)
1996
41
A selective delta 1 opioid receptor agonist derived from oxymorphone. Evidence for separate recognition sites for delta 1 opioid receptor agonists and antagonists. (8394935)
1993
42
Impairment of gamma carboxylation of circulating osteocalcin (bone gla protein) in elderly women. (1666807)
1991
43
Lipolytic effects on diacylglycerol accumulation in human adipose tissue in vitro. (2280178)
1990
44
Intervention for gallbladder disease. (2121354)
1990
45
The effects of hemodialysis with different membranes on middle molecules and uremic neuropathy. (2538398)
1989
46
Pemphigus foliaceus coexisting with toxic, multinodular goiter. (3771047)
1986
47
Multiple carboxylase deficiency due to deficiency of biotinidase. (3783319)
1986
48
An approach to KienbAPck's disease: triscaphe arthrodesis. (3980928)
1985
49
Incidence of mucopolysaccharidoses in Israel: is Hunter disease a "Jewish disease"? (6821579)
1980
50
Cefoxitin: intravenous pharmacokinetics and intramuscular bioavailability in kwashiorkor. (7387820)
1980

Variations for Hepatic Angiomyolipoma

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Expression for genes affiliated with Hepatic Angiomyolipoma

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Search GEO for disease gene expression data for Hepatic Angiomyolipoma.

Pathways for genes affiliated with Hepatic Angiomyolipoma

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Pathways related to Hepatic Angiomyolipoma according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.4KIT, MTOR

GO Terms for genes affiliated with Hepatic Angiomyolipoma

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Biological processes related to Hepatic Angiomyolipoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1phosphatidylinositol-mediated signalingGO:00480159.5KIT, MTOR
2visual learningGO:00085429.4KIT, MTOR
3protein autophosphorylationGO:00467779.1KIT, MTOR

Sources for Hepatic Angiomyolipoma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet