MCID: HPT008
MIFTS: 39

Hepatic Tuberculosis malady

Liver diseases, Gastrointestinal diseases categories

Summaries for Hepatic Tuberculosis

About this section


Disease Ontology:9 A gastrointestinal tuberculosis that involves infection located in liver, which results in the formation of tuberculous granulomas. the infection has symptom fever, has symptom anorexia, has symptom weight loss, has symptom abdominal pain and has symptom jaundice.

MalaCards based summary: Hepatic Tuberculosis, also known as tuberculosis of liver, is related to hepatitis and obstructive jaundice, and has symptoms including fever, anorexia and weight loss. An important gene associated with Hepatic Tuberculosis is SERPINA1 (serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1), and among its related pathways are Complement and coagulation cascades and Response to elevated platelet cytosolic Ca2+. The compounds aminopyrine and cefotetan have been mentioned in the context of this disorder. Affiliated tissues include liver, liver and lung.

Aliases & Classifications for Hepatic Tuberculosis

About this section
Sources:
9Disease Ontology, 43Novoseek, 60UMLS, 33MeSH, 55SNOMED-CT
See all sources

Hepatic Tuberculosis, Aliases & Descriptions:

Name: Hepatic Tuberculosis 9
Tuberculosis of Liver 9
 
Tuberculosis, Hepatic 60
Tuberculosis Hepatic 43


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Liver diseases, Gastrointestinal diseases


External Ids:

Disease Ontology9 DOID:407
SNOMED-CT55 186273003
MeSH33 D014386

Related Diseases for Hepatic Tuberculosis

About this section

Diseases related to Hepatic Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 82)
idRelated DiseaseScoreTop Affiliating Genes
1hepatitis30.8ALPP, SERPINA1, GGT1, F2
2obstructive jaundice30.2GGT1, ALPP
3hypercalcemia30.2ALPP, ALB
4portal hypertension29.7ALB, F2, GGT1
5hepatocellular carcinoma29.3GGT1, SERPINA1, ALB, F2, ALPP
6tuberculosis10.9
7gallbladder disease10.4GGT1
8dysfibrinogenemia10.3F2
9factor vii deficiency10.3F2
10hypersplenism10.3F2
11rickets10.2ALB, ALPP
12vascular disease10.2ALPP
13choledocholithiasis10.2ALPP, GGT1
14protein-losing enteropathy10.2SERPINA1, ALB
15secondary hyperparathyroidism of renal origin10.2ALB, ALPP
16skin disease10.2ALB, ALPP
17extrahepatic cholestasis10.2ALPP, GGT1
18hyperparathyroidism10.2ALB, ALPP
19cholelithiasis10.2ALPP, GGT1
20intrahepatic cholestasis10.2ALPP, GGT1
21fascioliasis10.2GGT1, ALPP
22adrenal hyperplasia, congenital, due to 11-beta-hydroxylase deficiency10.1ALPP, GGT1
23diarrhea10.1ALB, ALPP
24iga glomerulonephritis10.1SERPINA1, ALB
25hypersensitivity reaction type ii disease10.1ALPP, ALB
26nicotine dependence, protection against10.1GGT1, SERPINA1
27cholangiocarcinoma10.1GGT1, ALPP
28nephrotic syndrome10.1ALB, SERPINA1
29esophageal varix10.1ALB, F2
30acute liver failure10.1F2, ALB
31miliary tuberculosis10.1
32hepatorenal syndrome10.1F2, ALB
33varicose veins10.0F2, ALB
34fatty liver disease10.0ALPP, GGT1
35hepatic encephalopathy10.0F2, ALB
36pulmonary embolism10.0ALB, F2
37hyperhomocysteinemia10.0ALB, F2
38peritonitis10.0F2, ALB
39hyperglycemia10.0ALB, SERPINA1
40connective tissue disease10.0F2, ALB
41colorectal cancer10.0
42budd-chiari syndrome10.0
43sickle cell anemia10.0
44pulmonary tuberculosis10.0
45granulomatous hepatitis10.0
46portal vein thrombosis10.0
47acquired immunodeficiency syndrome10.0
48adult-onset still's disease10.0
49abdominal tuberculosis10.0
50adenocarcinoma10.0

Graphical network of the top 20 diseases related to Hepatic Tuberculosis:



Diseases related to hepatic tuberculosis

Symptoms for Hepatic Tuberculosis

About this section

Symptoms:

 9
  • fever
  • anorexia
  • weight loss
  • abdominal pain
  • jaundice

Drugs & Therapeutics for Hepatic Tuberculosis

About this section

Drug clinical trials:

Search ClinicalTrials for Hepatic Tuberculosis

Search NIH Clinical Center for Hepatic Tuberculosis

Genetic Tests for Hepatic Tuberculosis

About this section

Anatomical Context for Hepatic Tuberculosis

About this section

MalaCards organs/tissues related to Hepatic Tuberculosis:

31
Liver, Lung

FMA organs/tissues related to Hepatic Tuberculosis:

14
Liver

Animal Models for Hepatic Tuberculosis or affiliated genes

About this section

Publications for Hepatic Tuberculosis

About this section

Articles related to Hepatic Tuberculosis:

(show top 50)    (show all 70)
idTitleAuthorsYear
1
Primary/local hepatic tuberculosis without dissemination. (25628318)
2015
2
Isolated hepatic tuberculosis mimicking liver tumors in a dialysis patient. (25123829)
2014
3
A case of multiple macronodular hepatic tuberculosis difficult to differentiate from hepatocellular carcinoma with intrahepatic metastasis: CT-guided fine needle aspiration biopsy confirmed the diagnosis. (25550879)
2014
4
Isolated hepatic tuberculosis: a rare cause of hepatic mass lesions. (24918144)
2014
5
Isolated hepatic tuberculosis: An uncommon presentation of a common culprit. (25031646)
2014
6
Probable hepatic tuberculosis masquerading as Klatskin tumour in an immunocompetent patient. (24343799)
2013
7
Primary isolated hepatic tuberculosis. (23673179)
2013
8
The liver Metastatic Adenocarcinoma of Colorectal Cancer With Synchronous Isolated Hepatic Tuberculosis. (23967026)
2013
9
Hepatic tuberculosis: a rare cause of fluorodeoxyglucose hepatic superscan with background suppression on positron emission tomography. (24347039)
2013
10
Diagnosis and treatment of hepatic tuberculosis: report of five cases and review of literature. (24179582)
2013
11
Hepatic Tuberculosis Mimics Metastasis Revealed by 18F-FDG PET/CT. (24152632)
2013
12
Primary hepatic tuberculosis: a rare but fatal clinical entity if undiagnosed. (22575985)
2012
13
Pseudo-tumoral hepatic tuberculosis discovered after surgical resection. (24765426)
2012
14
Hepatic tuberculosis in a patient treated with infliximab. (21793022)
2011
15
Pseudo-tumoral hepatic tuberculosis: a report of two cases. (20306917)
2010
16
Primary nodular hepatic tuberculosis mimicking hepatic neoplasia in an immunocompetent host. (20140362)
2009
17
Primary hepatic tuberculosis in an immunocompetent patient: the Great Mimic. (19795040)
2009
18
Granulomatous hepatitis: tuberculosis or not? (18241177)
2008
19
CT appearance of primary localized nodular hepatic tuberculosis in an immunocompetent patient. (18541946)
2008
20
Isolated hepatic tuberculosis presenting as cystic-like and tumour-like mass lesions. (21490832)
2008
21
Isolated hepatic tuberculosis. (20071827)
2008
22
Macronodular hepatic tuberculosis necessitating hepatic resection: a diagnostic conundrum. (18031627)
2007
23
Localized hepatic tuberculosis presenting as fever of unknown origin. (17293928)
2006
24
Hypercalcemia in hepatic tuberculosis: a case report in Korea. (15827271)
2005
25
Hepatic tuberculosis mimicking carcinoma gall bladder. (15778524)
2005
26
Hepatic tuberculosis presenting as cholestatic jaundice. A case report. (16737053)
2005
27
The nodular form of hepatic tuberculosis: a review with five additional new cases. (14600128)
2003
28
Localized hepatic tuberculosis. (14962708)
2003
29
Clinical spectrum of hepatic tuberculosis: comparison between immunocompetent and immunocompromised hosts. (12930021)
2003
30
Hepatic tuberculosis--a case report. (12797646)
2002
31
Computed tomography and angiography in hepatic tuberculosis mimicking liver tumor. (11573902)
2001
32
Miliary hepatic tuberculosis not associated with splenic or lung involvement. A case report. (11016770)
2000
33
Isolated hepatic tuberculosis: report of five cases and review of the literature. (10398910)
1999
34
Hepatic tuberculosis: comparison of miliary and local form. (7744492)
1995
35
Nodular form of local hepatic tuberculosis: case report. (7714939)
1995
36
The "cluster" sign in macronodular hepatic tuberculosis: CT features. (8419431)
1993
37
Primary hepatic tuberculosis in homozygous alpha-1-antitrypsin deficiency. (1562749)
1992
38
The nodular form of local hepatic tuberculosis. A review. (2157746)
1990
39
Macronodular hepatic tuberculosis in a child: computed tomographic appearances. (2400887)
1990
40
Primary macronodular hepatic tuberculosis: US and CT appearances. (2210202)
1990
41
Hepatic tuberculosis; a rare case of bleeding gastric varices. (2238132)
1990
42
Isolated hepatic tuberculosis with scrofuloderma. (3671278)
1987
43
Local hepatic tuberculosis, the cause of a painful hepatic mass: case report and review of the literature. (3096551)
1986
44
Simultaneous hepatic tuberculosis, cirrhosis and hepatoma. A case report. (6320473)
1983
45
Hepatic tuberculosis simulating hepatic amoebiasis. (6671942)
1983
46
Spleno-hepatic tuberculosis due to Mycobacterium kansasii. (979821)
1976
47
Hepatic tuberculosis with haemosiderosis. (1052798)
1976
48
An unusual case of hemobilia. Hepatic tuberculosis with hemorrhage. (16097285)
1967
49
CLINICALLY ISOLATED HEPATIC TUBERCULOSIS]. (14149344)
1964
50
Hepatic tuberculosis in a patient with sickle-cell anemia who died of fatal post-transfusion hepatitis. (13031044)
1953

Variations for Hepatic Tuberculosis

About this section

Expression for genes affiliated with Hepatic Tuberculosis

About this section
Search GEO for disease gene expression data for Hepatic Tuberculosis.

Pathways for genes affiliated with Hepatic Tuberculosis

About this section

Pathways related to Hepatic Tuberculosis according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Complement Activation, Classical Pathway36
Complement and Coagulation Cascades36
9.5F2, SERPINA1
2
Show member pathways
9.4SERPINA1, ALB
39.3ALB, F2
4
Show member pathways
8.9ALB, F2, SERPINA1
5
Show member pathways
thioredoxin pathway36
8.8F2, ALB, GGT1

Compounds for genes affiliated with Hepatic Tuberculosis

About this section

Compounds related to Hepatic Tuberculosis according to GeneCards Suite gene sharing:

(show top 50)    (show all 80)
idCompoundScoreTop Affiliating Genes
1aminopyrine439.8GGT1, F2
2cefotetan43 1210.8F2, ALB
3dextran 70439.7F2, ALB
4terlipressin43 1210.7ALB, F2
5hepaplastin439.7ALB, F2
6cefoperazone43 1210.7F2, ALB
7oxcarbazepine43 49 1211.7GGT1, ALB
8gamma globulin439.7GGT1, ALB
9acenocoumarol43 49 1211.7ALB, F2
10phenprocoumon43 49 1211.7F2, ALB
11hydroxyethyl starch439.7ALB, F2
12amiodarone43 49 28 1212.7F2, GGT1
13ethacrynic acid43 1210.6ALB, GGT1
14diisopropylfluorophosphate439.6ALB, SERPINA1
15l-tryptophan49 28 43 24 1213.6GGT1, ALB
16alpha lipoic acid439.5SERPINA1, GGT1
17propylthiouracil43 2 1211.4GGT1, ALPP
18diflunisal43 1210.4ALB, ALPP
19phenylbutazone43 1210.3F2, SERPINA1, ALB
20antipyrine43 1210.3GGT1, F2, ALB
21cellulose acetate439.2ALB, ALPP
22vitamin a43 24 1211.2GGT1, ALB, SERPINA1
23hyaluronic acid43 2410.2F2, ALB, GGT1
24vitamin b6439.1ALPP, ALB
25silymarin439.1GGT1, F2
26fibrinogen439.1SERPINA1, F2, ALB
27methotrexate49 43 1211.1F2, ALB, GGT1
28ursodeoxycholic acid43 24 1211.0F2, ALPP, GGT1
2925-hydroxyvitamin d439.0ALPP, ALB
30bezafibrate43 28 1211.0ALPP, GGT1
31iron43 2410.0GGT1, SERPINA1, ALB
32sevoflurane49 43 1211.0ALPP, ALB, GGT1
33isoflurane49 43 1210.9ALPP, ALB, GGT1
34phosphorus438.9GGT1, ALPP, ALB
35pyridoxal 5-phosphate438.9GGT1, ALPP, ALB
36phenytoin43 49 28 1211.9ALB, ALPP, GGT1
37vitamin b12438.9ALPP, ALB, GGT1
38polyethylene glycol438.9F2, ALPP, ALB
39thyroxine43 249.9GGT1, ALB, ALPP
40tamoxifen43 49 28 1211.9ALPP, F2, GGT1
41calcitriol43 59 24 1211.9ALB, F2, ALPP
42ascorbic acid43 249.5SERPINA1, ALB, ALPP, GGT1
43cholesterol43 28 24 1211.5GGT1, SERPINA1, ALB, ALPP
44lactate438.4GGT1, ALPP, F2, ALB
45aspartate438.4GGT1, F2, ALPP, ALB
46alanine438.4ALB, ALPP, F2, GGT1
47cysteine438.4ALB, GGT1, ALPP, SERPINA1
48serine438.2ALPP, GGT1, SERPINA1, F2
49creatinine438.0GGT1, ALPP, F2, SERPINA1, ALB
50heparin43 28 24 1211.0GGT1, ALB, ALPP, SERPINA1, F2

GO Terms for genes affiliated with Hepatic Tuberculosis

About this section

Cellular components related to Hepatic Tuberculosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granule lumenGO:00310939.3ALB, SERPINA1
2blood microparticleGO:00725629.0ALB, F2
3extracellular spaceGO:00056158.9ALB, SERPINA1, F2

Biological processes related to Hepatic Tuberculosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1acute-phase responseGO:00069539.4SERPINA1, F2
2platelet degranulationGO:00025769.4ALB, SERPINA1
3platelet activationGO:00301688.9ALB, SERPINA1, F2
4blood coagulationGO:00075968.6F2, SERPINA1, ALB

Products for genes affiliated with Hepatic Tuberculosis

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Hepatic Tuberculosis

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet