MCID: HPT008
MIFTS: 46

Hepatic Tuberculosis malady

Infectious diseases, Gastrointestinal diseases, Liver diseases categories

Summaries for Hepatic Tuberculosis

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Disease Ontology:9 A gastrointestinal tuberculosis that involves infection located in liver, which results in the formation of tuberculous granulomas. the infection has symptom fever, has symptom anorexia, has symptom weight loss, has symptom abdominal pain and has symptom jaundice.

MalaCards based summary: Hepatic Tuberculosis, also known as tuberculosis of liver, is related to hepatitis and obstructive jaundice, and has symptoms including fever, anorexia and weight loss. An important gene associated with Hepatic Tuberculosis is SERPINA1 (serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1), and among its related pathways are Complement and coagulation cascades and Response to elevated platelet cytosolic Ca2+. The compounds aminopyrine and cefotetan have been mentioned in the context of this disorder. Affiliated tissues include liver, liver and lung.

Aliases & Classifications for Hepatic Tuberculosis

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Sources:
9Disease Ontology, 61UMLS, 44Novoseek, 34MeSH, 56SNOMED-CT
See all sources

Hepatic Tuberculosis, Aliases & Descriptions:

Name: Hepatic Tuberculosis 9
Tuberculosis of Liver 9 61
 
Tuberculosis, Hepatic 61
Tuberculosis Hepatic 44


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Infectious diseases
Anatomical: Gastrointestinal diseases, Liver diseases


External Ids:

Disease Ontology9 DOID:407
SNOMED-CT56 186273003
MeSH34 D014386

Related Diseases for Hepatic Tuberculosis

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Diseases related to Hepatic Tuberculosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 81)
idRelated DiseaseScoreTop Affiliating Genes
1hepatitis30.8F2, SERPINA1, ALPP, GGT1
2obstructive jaundice30.3GGT1, ALPP
3hypercalcemia30.2ALPP, ALB
4portal hypertension29.7F2, ALB, GGT1
5hypertension29.7GGT1, ALB, F2
6tuberculosis10.9
7gallbladder disease10.4GGT1
8dysfibrinogenemia10.3F2
9factor vii deficiency10.3F2
10hypersplenism10.3F2
11rickets10.2ALB, ALPP
12vascular disease10.2ALPP
13choledocholithiasis10.2ALPP, GGT1
14protein-losing enteropathy10.2SERPINA1, ALB
15secondary hyperparathyroidism of renal origin10.2ALB, ALPP
16skin disease10.2ALPP, ALB
17extrahepatic cholestasis10.2GGT1, ALPP
18hyperparathyroidism10.2ALPP, ALB
19cholelithiasis10.2ALPP, GGT1
20intrahepatic cholestasis10.2ALPP, GGT1
21fascioliasis10.2ALPP, GGT1
2221-hydroxylase deficiency10.2GGT1, ALPP
23diarrhea10.2ALPP, ALB
24berger disease10.1SERPINA1, ALB
25hypersensitivity reaction type ii disease10.1ALB, ALPP
26cholangiocarcinoma10.1ALPP, GGT1
27nephrotic syndrome10.1ALB, SERPINA1
28esophageal varix10.1ALB, F2
29acute liver failure10.1ALB, F2
30hepatorenal syndrome10.1F2, ALB
31varicose veins10.1F2, ALB
32miliary tuberculosis10.1
33fatty liver disease10.0GGT1, ALPP
34hepatic encephalopathy10.0F2, ALB
35pulmonary embolism10.0ALB, F2
36peritonitis10.0ALB, F2
37hyperhomocysteinemia10.0ALB, F2
38hyperglycemia10.0ALB, SERPINA1
39connective tissue disease10.0F2, ALB
40stroke, ischemic10.0ALB, F2
41colorectal cancer10.0
42hepatocellular carcinoma10.0
43sickle cell anemia10.0
44pulmonary tuberculosis10.0
45granulomatous hepatitis10.0
46adult-onset still's disease10.0
47acquired immunodeficiency syndrome10.0
48portal vein thrombosis10.0
49abdominal tuberculosis10.0
50adenocarcinoma10.0

Graphical network of the top 20 diseases related to Hepatic Tuberculosis:



Diseases related to hepatic tuberculosis

Symptoms for Hepatic Tuberculosis

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Symptoms:

 9
  • fever
  • anorexia
  • weight loss
  • abdominal pain
  • jaundice

Drugs & Therapeutics for Hepatic Tuberculosis

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Drug clinical trials:

Search ClinicalTrials for Hepatic Tuberculosis

Search NIH Clinical Center for Hepatic Tuberculosis

Genetic Tests for Hepatic Tuberculosis

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Anatomical Context for Hepatic Tuberculosis

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MalaCards organs/tissues related to Hepatic Tuberculosis:

32
Liver, Lung

FMA organs/tissues related to Hepatic Tuberculosis:

15
Liver

Animal Models for Hepatic Tuberculosis or affiliated genes

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Publications for Hepatic Tuberculosis

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Articles related to Hepatic Tuberculosis:

(show top 50)    (show all 69)
idTitleAuthorsYear
1
Isolated hepatic tuberculosis mimicking liver tumors in a dialysis patient. (25123829)
2014
2
Isolated hepatic tuberculosis: a rare cause of hepatic mass lesions. (24918144)
2014
3
Isolated hepatic tuberculosis: An uncommon presentation of a common culprit. (25031646)
2014
4
Probable hepatic tuberculosis masquerading as Klatskin tumour in an immunocompetent patient. (24343799)
2013
5
Primary isolated hepatic tuberculosis. (23673179)
2013
6
The liver Metastatic Adenocarcinoma of Colorectal Cancer With Synchronous Isolated Hepatic Tuberculosis. (23967026)
2013
7
Hepatic tuberculosis: a rare cause of fluorodeoxyglucose hepatic superscan with background suppression on positron emission tomography. (24347039)
2013
8
Diagnosis and treatment of hepatic tuberculosis: report of five cases and review of literature. (24179582)
2013
9
Hepatic Tuberculosis Mimics Metastasis Revealed by 18F-FDG PET/CT. (24152632)
2013
10
Primary hepatic tuberculosis: a rare but fatal clinical entity if undiagnosed. (22575985)
2012
11
Pseudo-tumoral hepatic tuberculosis discovered after surgical resection. (24765426)
2012
12
Hepatic tuberculosis in a patient treated with infliximab. (21793022)
2011
13
Pseudo-tumoral hepatic tuberculosis: a report of two cases. (20306917)
2010
14
The nodular form of hepatic tuberculosis: contrast-enhanced ultrasonographic findings with pathologic correlation. (20498462)
2010
15
Corticosteroids in the treatment of hepatic tuberculosis: case report and review of the literature. (20092380)
2010
16
Primary nodular hepatic tuberculosis mimicking hepatic neoplasia in an immunocompetent host. (20140362)
2009
17
Primary hepatic tuberculosis in an immunocompetent patient: the Great Mimic. (19795040)
2009
18
Granulomatous hepatitis: tuberculosis or not? (18241177)
2008
19
CT appearance of primary localized nodular hepatic tuberculosis in an immunocompetent patient. (18541946)
2008
20
Isolated hepatic tuberculosis presenting as cystic-like and tumour-like mass lesions. (21490832)
2008
21
Isolated hepatic tuberculosis. (20071827)
2008
22
Macronodular hepatic tuberculosis necessitating hepatic resection: a diagnostic conundrum. (18031627)
2007
23
Localized hepatic tuberculosis presenting as fever of unknown origin. (17293928)
2006
24
Hypercalcemia in hepatic tuberculosis: a case report in Korea. (15827271)
2005
25
Hepatic tuberculosis mimicking carcinoma gall bladder. (15778524)
2005
26
Hepatic tuberculosis presenting as cholestatic jaundice. A case report. (16737053)
2005
27
The nodular form of hepatic tuberculosis: a review with five additional new cases. (14600128)
2003
28
Localized hepatic tuberculosis. (14962708)
2003
29
Clinical spectrum of hepatic tuberculosis: comparison between immunocompetent and immunocompromised hosts. (12930021)
2003
30
Hepatic tuberculosis--a case report. (12797646)
2002
31
Computed tomography and angiography in hepatic tuberculosis mimicking liver tumor. (11573902)
2001
32
Miliary hepatic tuberculosis not associated with splenic or lung involvement. A case report. (11016770)
2000
33
Isolated hepatic tuberculosis: report of five cases and review of the literature. (10398910)
1999
34
Hepatic tuberculosis: comparison of miliary and local form. (7744492)
1995
35
Nodular form of local hepatic tuberculosis: case report. (7714939)
1995
36
The "cluster" sign in macronodular hepatic tuberculosis: CT features. (8419431)
1993
37
Primary hepatic tuberculosis in homozygous alpha-1-antitrypsin deficiency. (1562749)
1992
38
The nodular form of local hepatic tuberculosis. A review. (2157746)
1990
39
Macronodular hepatic tuberculosis in a child: computed tomographic appearances. (2400887)
1990
40
Primary macronodular hepatic tuberculosis: US and CT appearances. (2210202)
1990
41
Hepatic tuberculosis; a rare case of bleeding gastric varices. (2238132)
1990
42
Isolated hepatic tuberculosis with scrofuloderma. (3671278)
1987
43
Local hepatic tuberculosis, the cause of a painful hepatic mass: case report and review of the literature. (3096551)
1986
44
Simultaneous hepatic tuberculosis, cirrhosis and hepatoma. A case report. (6320473)
1983
45
Hepatic tuberculosis simulating hepatic amoebiasis. (6671942)
1983
46
Spleno-hepatic tuberculosis due to Mycobacterium kansasii. (979821)
1976
47
Hepatic tuberculosis with haemosiderosis. (1052798)
1976
48
An unusual case of hemobilia. Hepatic tuberculosis with hemorrhage. (16097285)
1967
49
CLINICALLY ISOLATED HEPATIC TUBERCULOSIS]. (14149344)
1964
50
Hepatic tuberculosis in a patient with sickle-cell anemia who died of fatal post-transfusion hepatitis. (13031044)
1953

Variations for Hepatic Tuberculosis

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Expression for genes affiliated with Hepatic Tuberculosis

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Expression patterns in normal tissues for genes affiliated with Hepatic Tuberculosis

Search GEO for disease gene expression data for Hepatic Tuberculosis.

Pathways for genes affiliated with Hepatic Tuberculosis

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Pathways related to Hepatic Tuberculosis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Complement Activation, Classical Pathway37
Complement and Coagulation Cascades37
9.5SERPINA1, F2
2
Show member pathways
9.4ALB, SERPINA1
39.4ALB, SERPINA1
49.3ALB, F2
5
Show member pathways
8.9F2, SERPINA1, ALB
6
Show member pathways
thioredoxin pathway37
8.8GGT1, ALB, F2

Compounds for genes affiliated with Hepatic Tuberculosis

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Compounds related to Hepatic Tuberculosis according to GeneCards/GeneDecks:

(show top 50)    (show all 80)
idCompoundScoreTop Affiliating Genes
1aminopyrine449.8F2, GGT1
2cefotetan44 1210.8ALB, F2
3dextran 70449.7ALB, F2
4terlipressin44 1210.7F2, ALB
5hepaplastin449.7F2, ALB
6oxcarbazepine44 50 1211.7GGT1, ALB
7cefoperazone44 1210.7ALB, F2
8gamma globulin449.7ALB, GGT1
9acenocoumarol44 50 1211.7ALB, F2
10phenprocoumon44 50 1211.7F2, ALB
11hydroxyethyl starch449.7F2, ALB
12amiodarone44 50 29 1212.7GGT1, F2
13ethacrynic acid44 1210.6GGT1, ALB
14diisopropylfluorophosphate449.6ALB, SERPINA1
15l-tryptophan50 29 44 25 1213.6ALB, GGT1
16silymarin449.4GGT1, F2
17propylthiouracil44 3 1211.4ALPP, GGT1
18diflunisal44 1210.4ALB, ALPP
19phenylbutazone44 1210.3ALB, SERPINA1, F2
20antipyrine44 1210.3GGT1, ALB, F2
21cellulose acetate449.2ALPP, ALB
22alpha lipoic acid449.2GGT1, SERPINA1
23vitamin a44 25 1211.2GGT1, ALB, SERPINA1
24hyaluronic acid44 2510.2GGT1, ALB, F2
25vitamin b6449.1ALPP, ALB
26fibrinogen449.1ALB, SERPINA1, F2
27methotrexate50 44 1211.1F2, ALB, GGT1
28ursodeoxycholic acid44 25 1211.0GGT1, ALPP, F2
2925-hydroxyvitamin d449.0ALB, ALPP
30bezafibrate44 29 1211.0GGT1, ALPP
31iron44 2510.0SERPINA1, ALB, GGT1
32sevoflurane50 44 1211.0ALB, ALPP, GGT1
33isoflurane50 44 1210.9GGT1, ALPP, ALB
34phosphorus448.9GGT1, ALPP, ALB
35pyridoxal 5-phosphate448.9ALB, ALPP, GGT1
36phenytoin44 50 29 1211.9GGT1, ALPP, ALB
37vitamin b12448.9ALB, ALPP, GGT1
38polyethylene glycol448.9F2, ALB, ALPP
39thyroxine44 259.9ALB, ALPP, GGT1
40tamoxifen44 50 29 1211.9F2, ALPP, GGT1
41calcitriol44 60 25 1211.9ALPP, ALB, F2
42ascorbic acid44 259.5SERPINA1, ALB, ALPP, GGT1
43cholesterol44 29 25 1211.5GGT1, ALPP, ALB, SERPINA1
44lactate448.4F2, ALB, ALPP, GGT1
45aspartate448.4GGT1, ALPP, ALB, F2
46alanine448.4GGT1, ALPP, ALB, F2
47cysteine448.4GGT1, ALPP, ALB, SERPINA1
48serine448.2GGT1, ALPP, SERPINA1, F2
49creatinine448.0GGT1, ALPP, ALB, SERPINA1, F2
50heparin44 29 25 1211.0F2, SERPINA1, ALB, ALPP, GGT1

GO Terms for genes affiliated with Hepatic Tuberculosis

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Cellular components related to Hepatic Tuberculosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granule lumenGO:0310939.3ALB, SERPINA1
2blood microparticleGO:0725629.0ALB, F2
3extracellular spaceGO:0056158.9ALB, SERPINA1, F2

Biological processes related to Hepatic Tuberculosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1acute-phase responseGO:0069539.4SERPINA1, F2
2platelet degranulationGO:0025769.4ALB, SERPINA1
3platelet activationGO:0301688.9ALB, SERPINA1, F2
4blood coagulationGO:0075968.6F2, SERPINA1, ALB

Products for genes affiliated with Hepatic Tuberculosis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Hepatic Tuberculosis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
29IUPHAR
30KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet