Summaries for Hepatitis

Sources:
23MedlinePlus, 44Wikipedia, 22MalaCards
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MedlinePlus: Your liver helps your body digest food, store energy and remove poisons. hepatitis is a swelling of the liver that makes it stop working well. it can lead to scarring, called cirrhosis, or to cancer. viruses cause most cases of hepatitis. the type of hepatitis is named for the virus that causes it; for example, hepatitis a, hepatitis b or hepatitis c. drug or alcohol use can also lead to hepatitis. in other cases, your body mistakenly attacks its own tissues. you can help prevent some viral forms by getting a vaccine. sometimes hepatitis goes away by itself. if it does not, it can be treated with drugs. sometimes hepatitis lasts a lifetime. some people who have hepatitis have no symptoms. others may have loss of appetite nausea and vomiting diarrhea dark-colored urine and pale bowel movements stomach pain jaundice, yellowing of skin and eyes23

MalaCards: Hepatitis, also known as chronic persistent hepatitis, is related to carcinoma and leukemia. An important gene associated with Hepatitis is RSF1 (remodeling and spacing factor 1), and among its related pathways are p38 Signaling and Immune System. The drugs milk thistle and astragalus and the compounds serine and estrogen have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, whole blood and lymph node, and related mouse phenotypes are mortality/aging and homeostasis/metabolism.

Wikipedia: Hepatitis (plural hepatitides) is a medical condition defined by the inflammation of the liver and...44 more...

Aliases & Descriptions for Hepatitis

Sources:
6Disease Ontology, 8DISEASES, 32Novoseek , 23MedlinePlus, 43UMLS, 40SNOMED-CT, 19ICD9CM
See all sources

Aliases & Descriptions:

hepatitis 6 8 32 23 43
chronic persistent hepatitis 6 32
acute hepatitis 6 43
acute and subacute liver necrosis nos (disorder) 6
acute and subacute liver necrosis (disorder) 6
chronic persistent hepatitis (disorder) 6
acute and subacute necrosis of liver 6
acute and subacute liver necrosis 6
acute/subac. necrosis of liver 6
hepatitis, chronic persistent 43
chronic persistant hepatitis 6
acute hepatitis (disorder) 6
hepatitis, chronic 43
hepatitis chronic 32
hepatitis, animal 43
chronic hepatitis 6
animal hepatitis 6

Related Diseases for Hepatitis

Sources:
13GeneCards, 14GeneDecks
See all sources

Disease types for hepatitis c family:

hepatitis a hepatitis e
hepatitis d hepatitis b
hepatitis

Diseases related to hepatitis by text searches and GeneDecks gene sharing:

(show top 50)    (show all 1039)
idRelated DiseaseScoreTop Affiliating Genes
1carcinoma501.7ZNF267, PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIAS3
2leukemia441.4PIK3CB, PIGA, PIK3CD, PIAS2, PIK3CA, PIK3R3
3prostatitis407.8PIK3CB, PIK3CD, PIAS2, PIK3CA, PIK3R3, PIAS3
4neuronitis380.4ZNF638, PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2
5pancreatitis362.5PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
6hepatocellular carcinoma350.3PIK3CB, PIK3CD, PIK3CA, PIK3R1, PIK3IP1, PIK3CG
7colorectal cancer323.9ZNF318, PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2
8adenocarcinoma318.9PIK3CB, PIK3CA, PIK3R1, PIK3C2A, PIK3CG, PIN1
9arthritis311.8PIK3CD, PIK3CG, PIN1, LRP1, SH2B3, PDCD1
10melanoma311.4PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
11thyroiditis302.8PIK3CB, PIK3CA, PIK3R1, PIK3C2A, PIK3CG, PIN1
12rheumatoid arthritis285.5PIK3CD, PIK3CG, PIN1, LRP1, SH2B3, PDCD1
13ovarian cancer266.5ZNF318, PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R1
14gastric cancer265.7PIK3CB, PIK3CA, PIK3R1, PIAS1, PIK3CG, PIN1
15cholesterol265.4PIK3CB, PIK3CD, PIK3CA, PIK3R2, PIK3R1, PIAS1
16fibrosis259.7PIK3CA, PIAS3, PIK3CG, PIN1, LRP1, KLF6
17hypoxia246.5PIK3CB, PIK3CD, PIK3CA, PIK3R1, PIAS4, PIK3C2A
18alzheimer's disease243.6PIK3CB, PIK3CD, PIK3CA, PIK3R1, PI4KB, PIK3CG
19colon cancer240.2PIK3CB, PIAS2, PIK3CA, PIK3R3, PIK3R1, PIAS1
20esophagitis234.2PIK3CB, PIK3CA, PIK3C2A, PIK3CG, PIN1, PIK3C3
21cervicitis233.7PIK3CA, PIK3CG, PIN1, NCL, NCR1, NCR2
22tuberculosis231.4PIK3CG, PIK3C3, PIM1, NCR1, PDCD1, PDCD1LG2
23diabetes mellitus226.7PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
24atherosclerosis225.1PIK3C2A, PIK3CG, LRP1, LRP8, COG2, KLF2
25breast carcinoma224.3PIK3CA, PIK3R1, PIK3CG, LRP1, NCL, NCOA3
26lupus erythematosus224.2PIK3CD, PIK3C2A, PIK3CG, SH2B3, COG2, NCF2
27malaria224.1PIGA, PIAS2, PIAS3, PIAS4, PIAS1, PI4KB
28cerebritis223.5PIK3R1, PIK3C2A, PIK3CG, LRP1, LRP8, COG2
29obesity220.1ZNF318, PIK3CB, PIK3CA, PIK3R1, PIK3C2A, PIK3CG
30neuroblastoma219.4PIK3CB, PIK3CD, PIAS2, PIK3CA, PIK3R1, PIK3CG
31pancreatic cancer217.3PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
32sarcoma211.5PIK3CB, PIK3CD, PIK3CA, PIK3R2, PIK3R1, PIAS4
33retinitis209.1PIGA, PIK3CA, PIK3C2A, PIK3CG, PIM1, LRAT
34myeloid leukemia208.0PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
35hypertension207.9PIK3CB, PIK3R1, PIK3C2A, PIK3CG, PIM1, LRP1
36adenoma198.3PIK3CA, LRMP, NCAM1, NCF2, NCOA3, NCOR2
37ischemia187.5PIK3CA, PIK3C2A, PIK3CG, WDR26, COG2, NCAM1
38gonococcal synovitis177.9PIK3CB, PIK3CA, PIK3R1, PIK3CG, LRP1, NCAM1
39anemia173.8PIGA, PIM1, KLF2, RFX1, NCAM1, PDCD1
40pneumonia171.2PIK3C2A, SH2D3A, COG2, RELA, VTN, SFTPC
41colon carcinoma169.2PIK3CB, PIK3CA, PIK3R2, PIK3R1, PIAS1, PIK3CG
42myocardial infarction169.0PIK3C2A, PIK3CG, LRP1, LRP8, SH2B3, COG2
43nephropathy168.9LRP1, COG2, PDCD1, RELA, REN, RETN
44psoriasis165.8LRP1, RETN, CNR1, KIR2DS3, KIR2DS5, KIR3DL2
45inflammatory bowel disease165.4RELA, RETN, KIT, KIR2DL1, KIR2DL3, VWF
46cervical cancer163.6PIK3CA, PIK3CG, PIN1, NCL, NCR1, NCR2
47influenza162.8PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
48peritonitis160.0PIK3C2A, LRP1, COG2, NCR1, NCR2, PDE3B
49insulin resistance158.6ZNF318, PIK3CB, PIK3CA, PIK3R2, PIK3R1, PIK3CG
50squamous cell carcinoma157.8PIK3CB, PIK3CA, PIN1, PIM1, LRAT, NCL

Graphical network of the top 20 diseases related to hepatitis:



Graphical network of diseases related to hepatitis

Clinical Features for Hepatitis

Drugs & Therapeutics for Hepatitis

Sources:
4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials, 43UMLS, 28NDF-RT
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Approved drugs:

Search CenterWatch for hepatitis

Drug clinical trials:

Search ClinicalTrials for hepatitis

Search NIH Clinical Center for hepatitis

Search CenterWatch for hepatitis

Inferred drug relations via UMLS/NDF-RT:

43 28 astragalus, astragalus extract, milk thistle

Genetic Tests for Hepatitis

Anatomical Context for Hepatitis

Sources:
22MalaCards
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MalaCards organs/tissues related to hepatitis:

22
Bone marrow, Whole blood, Lymph node, Thymus, Brain, Cortex, Spinal cord, Heart, Smooth muscle, Skeletal muscle, Small intestine, Colon, Adipocyte, Kidney, Liver, Lung, Pancreas, Thyroid, Breast, Skin, Ovary, Prostate, Testis, Myeloid, Monocytes, Nk cells, T cells, B lymphoblasts, B cells, Endothelial, Fetal brain, Parietal lobe, Temporal lobe, Globus pallidus, Hypothalamus, Caudate nucleus, Pons, Fetal liver, Fetal lung, Fetal thyroid, Pancreatic islet, Adrenal cortex, Pituitary, Testis germ

Phenotypes for genes affiliated with Hepatitis

Sources:
25MGI
See all sources

MGI Mouse Phenotypes related to hepatitis:

25 (show all 29)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1mortality/agingMP:0010768INFPIK3CB, PIGA, PIK3CA, PIAS4, PIAS1, PIK3C2A
2homeostasis/metabolism phenotypeMP:0005376225.1PIK3CB, PIK3CD, PIK3CA, PIK3R2, PIK3R1, PIK3C2A
3growth/size phenotypeMP:0005378161.4PIK3CB, PIGA, PIK3CA, PIK3R1, PIAS1, PIK3C2A
4cardiovascular system phenotypeMP:0005385143.7PIK3CB, PIK3CD, PIK3CA, PIK3R2, PIK3R1, PIK3CG
5behavior/neurological phenotypeMP:0005386112.4PIGA, PIK3CA, PIK3C3, LRP1, LRP8, SH2D3C
6hematopoietic system phenotypeMP:0005397112.1PIGA, PIAS4, PIM1, SH2B2, SH2B3, SH2D3C
7immune system phenotypeMP:000538793.6PIK3CD, PIAS4, PIAS1, PIK3R5, PIK3C3, LRP1
8normal phenotypeMP:000287390.1PI4KA, PIAS2, PIK3R1, PIK3C3, LRP1, LRP8
9integument phenotypeMP:001077186.3PIGA, PIK3CG, PIN1, SH3BP2, KLF6, NCOA3
10reproductive system phenotypeMP:000538979.1PIGA, PIK3CA, LRAT, LRP8, SH2D3C, KLF6
11tumorigenesisMP:000200676.6PIK3CB, PIGA, PIK3CA, PIK3R2, PIK3R1, NCOA3
12liver/biliary system phenotypeMP:000537069.9PIK3C3, SH3BP2, KLF15, KLF2, KLF6, NCOA3
13renal/urinary system phenotypeMP:000536766.8KLF15, NCK1, NCK2, NCOA3, PDCD1, REN
14no phenotypic analysisMP:000301256.4PIK3CD, PIK3R1, SH2D3C, PDCD1LG2, SGK1, CNR1
15adipose tissue phenotypeMP:000537553.9PIK3CA, PIK3R1, PIK3C2A, LRP1, KLF15, KLF3
16respiratory system phenotypeMP:000538843.1SH3BP2, KLF2, KIF1B, SFRP4, SFTPC, SFTPD
17pigmentation phenotypeMP:000118629.9NCOA6, PDE3B, KIT, KITLG, PCBD1, BTD
18other phenotypeMP:000539527.5SH2B3, CNR1, RBP2, SERPINH1, RARA, RARB
19endocrine/exocrine gland phenotypeMP:000537917.5SELL, SERPINA5, VIPR1, ZC3HC1, LDLR, XDH
20limbs/digits/tail phenotypeMP:0005371INF, NCOA6, RELA, KIT, KITLG, SFRP1
21craniofacial phenotypeMP:0005382INFPIGA, , SH3BP2, KLF2, NCOA3, NCOA6
22muscle phenotypeMP:0005369INFPIK3CA, PIK3R2, PIK3R1, PIK3CG, PIK3C3,
23nervous system phenotypeMP:0003631INFPIGA, , LRAT, LRP1, LRP8, SH2D3C
24digestive/alimentary phenotypeMP:0005381INFPIGA, , SH3BP2, NCOA3, NCOA6, NCOR2
25cellular phenotypeMP:0005384INFPIK3CB, PIGA, PIK3CD, PIK3CA, PIK3R1, PIK3R5
26skeleton phenotypeMP:0005390INFPIGA, PIK3CD, PIK3CG, , LRP1, SH3BP2
27hearing/vestibular/ear phenotypeMP:0005377INF, COCH, NCOA3, KIT, KITLG, RB1
28embryogenesis phenotypeMP:0005380INFPIK3CB, PIGA, PIK3CA, PIK3C3, , KLF2
29vision/eye phenotypeMP:0005391INFPIK3CA, PIN1, , LRAT, SH3BP2, NCAM1

Publications for genes affiliated with Hepatitis

Sources:
35PubMed
See all sources

Articles related to hepatitis:

(show top 50)    (show all 10743)
idTitleAuthorsYearAffiliating Genes
1Extended lamivudine consolidation therapy in hepatiti s B e antigen-positive chronic hepatitis B patients improves sustained hepatiti s B e antigen seroconversion. (20030580)Kuo Y.H.... Lee C.M.2010GPT
2Comparison between quantitative hepatitis B surface a ntigen, hepatitis B e-antigen and hepatitis B virus DNA levels for predicting v irological response to pegylated interferon-alpha-2b therapy in hepatitis B e-a ntigen-positive chronic hepatitis B. (20070399)Tangkijvanich P.... Poovorawan Y.2010IFNA2
3Impact of amino acid substitutions in the hepatitis C virus genotype 1b core region on liver steatosis and hepatic oxidative stress in patients with chronic hepatitis C. (19951380)Tachi Y.... Goto H.2010GPT
4Correlation of liver stiffness and histological featu res in healthy persons and in patients with occult hepatitis B, chronic active hepatitis B, or hepatitis B cirrhosis. (19920809)Fung J.... Yuen M.F.2010GPT
5Hepatitis B virus X protein shifts human hepatic transforming growth factor (TGF)-beta signaling from tumor suppression to oncogenesis in early chronic hepatitis B. (19263472)Murata M.... Okazaki K.2009TGFB1, SMAD3, RSF1
6Hepatic iron, serum ferritin, HFE mutation, and hepat ic fibrosis in chronic hepatitis C. (19602897)Won J.E.... Kim H.2009HFE
7Clinical features and predictors of outcome in acute hepatitis A and hepatitis E virus hepatitis on cirrhosis. (19267864)Radha Krishna Y.... Choudhuri G.2009GPT
8Is there a meaningful serum hepatitis B virus DNA cutoff level for therapeutic decisions in hepatitis B e antigen-negative chronic hepatitis B virus infection? (18924246)Papatheodoridis G.V.... Archimandritis A.J.2008LOC100128356
9IP-10 correlates with hepatitis C viral load, hepatic inflammation and fibrosis and predicts hepatitis C virus relapse or non-response in HIV-HCV coinfection. (19195322)Reiberger T.... Peck-Radosavljevic M.2008CXCL10
10Correlation of hepatic steatosis with body mass index, serum ferritin level and hepatic fibrosis in Japanese patients with chronic hepatitis C. (17397514)Sumida Y.... Sakai K.2007SLC17A5
11Predictive factors for reactivation of hepatitis B following hepatitis B e antigen seroconversion in chronic hepatitis B. (17935720)Chu C.M.... Liaw Y.F.2007GPT
12Fulminant hepatic failure in a case of autoimmune hepatitis in hepatitis C during peg-interferon-alpha 2b plus ribavirin treatment. (17708618)Kogure T.... Shimosegawa T.2007IFNA1
13Hepatic stellate cell activation in liver transplant patients with hepatitis C recurrence and in non-transplanted patients with chronic hepatitis C. (17600343)Cisneros L.... Rimola A.2007TGFB1
14(99m)Tc-HEPIDA hepatic clearance as a diagnostic tool: usefulness of a single sample plasma and hepatic clearance of (99m)Tc-HEPIDA for assessment of hepatic parenchyma performance. (17304475)Surma M.J.... KuA_mierek J.2006ALB, SLC17A5
15Early reduction of infected hepatocytes by activated immunity at the time of interferon withdrawal hepatitis followed by lamivudine administration resulted in higher seroconversion in hepatitis Be antigen-positive patients with chronic hepatitis B. (16568374)Shindo M.... Okuno T.2006IFNA1
16Hepatitis C virus-specific immune responses and quasi-species variability at baseline are associated with nonresponse to antiviral therapy during advanced hepatitis C. (16518754)Morishima C.... Lindsay K.L.2006IFNA1
17Fibrinogen-like protein 2 fibroleukin expression and its correlation with disease progression in murine hepatitis virus type 3-induced fulminant hepatitis and in patients with severe viral hepatitis B. (16437596)Zhu C.L.... Ning Q.2005FGL2
18Comparison of recurrence after hepatic resection in p atients with hepatitis B vs. hepatitis C-related small hepatocellular carcinoma in hepatitis B virus endemic area. (15780044)Huang Y.H.... Lee S.D.2005ALB
19The relationship between hepatic expression, serum level of TGFbeta1 and the hepatic fibrosis in patients with viral hepatitis (15161500)Li B.S.... Liu F.2004TGFB1
20Interferon-gamma inhibits interferon-alpha signalling in hepatic cells: evidence for the involvement of STAT1 induction and hyperexpression of STAT1 in chronic hepatitis C. (14690454)Radaeva S.... Gao B.2004STAT1, IFNG, STAT2
21Promoting hepatic growth factor in the treatment of heavy type hepatitis and severe chronic hepatitis: a multicenter clinical study. (15313673)Xu J.H.... Lu W.L.2004F2, ALB, AFP
22HFE gene mutations, hepatic iron content, and histological severity in hepatitis C virus-induced chronic hepatitis (14972004)Ladero J.M.... Diaz-Rubio M.2003HFE
23Expression of the chemokine IP-10 correlates with the accumulation of hepatic IFN-gamma and IL-18 mRNA in chronic hepatitis C but not in hepatitis B. (12794718)Mihm S.... Ramadori G.2003IL18, IFNG, CXCL10
24Hepatitis C virus genotypes and hepatic fibrosis regulate 24-h decline of serum hepatitis C virus RNA during interferon therapy in patients with chronic hepatitis C. (12653888)Karino Y.... Matsushima T.2003IFNA1
25Augmented hepatic interferon gamma expression and T-cell influx characterize acute hepatitis progressing to recovery and residual lifelong virus persistence in experimental adult woodchuck hepatitis virus infection. (11679978)Hodgson P.D.... Michalak T.I.2001IFNG
26High doses of alpha-interferon are required in chronic hepatitis due to coinfection with hepatitis B virus and hepatitis C virus: long term results of a prospective randomized trial. (11693335)Villa E.... Manenti F.2001IFNA1
27Immunoreactivity to various human cytochrome P450 proteins of sera from patients with autoimmune hepatitis, chronic hepatitis B, and chronic hepatitis C. (11204250)Miyakawa H.... Kako M.2000CYP1A2
28Role of hepatitis B virus in non-B, non-C chronic liver disease: in vitro proliferation and interferon-gamma production of peripheral blood mononuclear cells in response to hepatitis B core antigen and its relation to hepatitis activity. (10638591)Niigaki M.... Kinoshita Y.2000IFNG
29Disorders of hepatic sinusoids and perisinusoidal space in chronic viral hepatitis B and its relationship to hepatic fibrosis (10951618)Liu J.... Ma Y.2000FN1, ACTC1
30Eradication of hepatitis C virus 1b by interferon in a health care worker with acute hepatitis following needlestick transmission from a patient with chronic hepatitis C unresponsive to interferon. (11099068)Toyoda H.... Nakano H.2000IFNA1
31Hepatitis B or hepatitis C virus infection is a risk factor for severe hepatic cytolysis after initiation of a protease inhibitor-containing antiretroviral regimen in human immunodeficiency virus-infected patients. The APROCO Study Group. (11083658)SavA"s M.... Leport C.2000GPT
32Fulminant hepatitis associated with hepatitis A virus superinfection in patients with chronic hepatitis C. (10866837)Vento S.2000HLA-A
33Apoptosis and hepatic cell proliferation in autoimmune hepatitis and chronic viral hepatitis C in children: analysis of APO-1/Fas (CD95), bcl-2 and Ki67 expression (10910654)Cielecka-Kuszyk J.... Woynarowski M.1999FAS
34Clinical evaluation of the branched DNA assay for hepatitis B virus DNA detection in patients with chronic hepatitis B lacking hepatitis B e antigen and treated with interferon-alpha. (9857350)Habersetzer F.... TrAcpo C.1998IFNA1
35Relevance of inapparent coinfection by hepatitis B virus in alpha interferon-treated patients with hepatitis C virus chronic hepatitis. (9093946)Zignego A.L.... Gentilini P.1997IFNA1
36Hepatic expression of inducible nitric oxide synthase transcripts in chronic hepatitis C virus infection: relation to hepatic viral load and liver injury. (9252158)Mihm S.... Ramadori G.1997NOS2
37Are alanine aminotransferase, hepatitis B virus DNA or IgM antibody to hepatitis B core antigen serum levels predictors of histological grading in chronic hepatitis B? (9138277)Zavaglia C.... IDEO G.1997CD40LG, GPT
38Importance of pretreatment viral load and monitoring of serum hepatitis C virus RNA in predicting responses to interferon-alpha2a treatment of chronic hepatitis C. Hanshin Chronic Hepatitis C Study Group. (9402109)Wada M.... Shimoyama T.1997IFNA2
39Hepatic expression of hepatitis C virus RNA in chronic hepatitis C: a study by in situ reverse-transcription polymerase chain reaction. (8675145)Lau G.K.... Lau J.Y.1996IFNA1
40A randomized controlled trial of thymosin-alpha1 vers us interferon alfa treatment in patients with hepatitis B e antigen antibody--a nd hepatitis B virus DNA--positive chronic hepatitis B. (8855175)Andreone P.... Gasbarrini G.1996PTMA
41Nucleotide sequence diversity of hypervariable region 1 of hepatitis C virus in Japanese hemophiliacs with chronic hepatitis C and patients with chronic posttransfusion hepatitis C. (8695870)Toyoda H.... Hayakawa T.1996VIPR1
42Quantitative assessment of hepatitis C virus RNA and IgM antibodies to hepatitis C core in chronic hepatitis C. (8834020)Martinelli A.L.... Dusheiko G.M.1996CD40LG
43Fulminant hepatic failure in pregnant women: acute fatty liver or acute viral hepatitis? (8836897)Hamid S.S.... Fields H.1996F2
44Genetic heterogeneity in the precore region of hepatitis B virus in hepatitis B e antigen-negative chronic hepatitis B patients: spontaneous seroconversion and interferon-induced seroconversion. (7666040)Karasawa T.... Toda G.1995IFNA1
45Induction of T-helper cell response to hepatitis B core antigen in chronic hepatitis B: a major factor in activation of the host immune response to the hepatitis B virus. (7557849)Marinos G.... Williams R.1995IFNG
46Displacement of hepatitis B virus by hepatitis C virus as the cause of continuing chronic hepatitis. (8143971)Liaw Y.F.... Chu C.M.1994GPT
47The role of hepatitis C virus in fulminant viral hepatitis in an area with endemic hepatitis A and B. (8020661)Chu C.M.... Liaw Y.F.1994CD40LG
48Clinical predictors of response to recombinant interferon-alpha treatment in patients with chronic non-A, non-B hepatitis (hepatitis C). The Hepatitis Interventional Therapy Group. (8790560)Davis G.L.... Carey W.1994IFNA1
49The role of pre-core hepatitis B virus mutants on the long-term outcome of chronic hepatitis B virus hepatitis. A longitudinal study . (7930478)Lai M.E.... Balestrieri A.1994GPT
50Hepatitis B x antigen and polymerase antibodies in the serum of hepatitis B carriers with or without hepatitis delta virus infection. Effects of interferon treatment. (1500693)Lega L.... Feitelson M.A.1992IFNA1

Expression for genes affiliated with Hepatitis

Sources:
1BioGPS
See all sources
Expression patterns in normal tissues for genes affiliated with Hepatitis

Pathways for genes affiliated with Hepatitis

Sources:
36QIAGEN, 38Reactome, 20KEGG, 10EMD Millipore, 41Thomson Reuters, 34PharmGKB
See all sources

Pathways related to hepatitis according to GeneDecks:

(show top 50)    (show all 331)
idPathwayScoreTop Affiliating Genes
1p38 Signaling3660.5KIT, KITLG, VEGFC, BMP1, BMP10, BMP4
2Immune System3845.4PIAS1, NCAM1, NCR2, PDCD1, PDCD1LG2, KIR2DS5
3PAK Pathway3644.1PIK3R3, PIK3R2, PIK3R1, KIT, KITLG, VEGFC
4NFAT in Immune Response3638.8PIK3R3, PIK3R2, PIK3R1, KIT, KITLG, VEGFC
5Phospholipase-C Pathway3638.5KIT, KITLG, VEGFC, BMP1, BMP10, BMP4
6Glucocorticoid Receptor Signaling3636.6NCOA3, NCOR2, BMP1, BMP10, BMP4, BMP6
7Renin-Angiotensin Pathway3636.3PIK3R3, PIK3R2, PIK3R1, REN, KIT, KITLG
8PEDF Induced Signaling3635.3RELA, SERPINF1, BRAF, BMP1, BMP10, BMP4
9NF-KappaB Family Pathway3635.0PIK3R3, PIK3R2, PIK3R1, RELA, KITLG, VEGFC
10Regulation of eIF4 and p70S6K3631.8PIK3R3, PIK3R2, PIK3R1, VEGFC, BMP1, BMP10
11Metabolism of lipids and lipoproteins3830.1PI4KA, PI4KB, LRAT, NCOR2, RDH11, GC
12eIF2 Pathway3629.0PIK3R3, PIK3R2, PIK3R1, KIT, KITLG, BRAF
1314-3-3 Induced Intracellular Signaling3628.7PIK3R3, PIK3R2, PIK3R1, KITLG, VEGFC, BMP1
14Activation of PKC through GPCR3628.3PIK3R3, PIK3R2, PIK3R1, PDE3B, KIT, KITLG
15Signaling Involved in Cardiac Hypertrophy3627.9PIK3R3, PIK3R2, PIK3R1, BRAF, RAF1, RAC1
16Nanog in Mammalian ESC Pluripotency3627.5KIT, KITLG, BRAF, VEGFC, BMP1, BMP10
17eNOS Signaling3627.1PIK3R3, PIK3R2, PIK3R1, KIT, KITLG, BMP1
18Cell adhesion molecules (CAMs)2025.7NCAM1, PDCD1LG2, CNTN2, CNTNAP2, SELL, SELP
19Telomerase Components in Cell Signaling3624.8KIT, KITLG, RB1, VEGFC, MYC, BMP1
20Insulin signaling pathway2024.5PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
21Leishmaniasis2024.1NCF2, RELA, MYD88, JUN, JAK1, JAK2
22Neurotrophin signaling pathway2023.3PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R5
23Leukocyte transendothelial migration2022.8PIK3CB, PIK3CD, PIK3R3, PIK3R2, PIK3R1, PIK3R5
2414-3-3 Induced Apoptosis3622.7PIK3R3, PIK3R2, PIK3R1, MYD88, BID, BCL2
25Autoimmune thyroid disease2022.0CGA, CD28, CD86, CD40LG, CD80, CD40
26IGF1R Signaling3622.0PIK3R3, PIK3R2, PIK3R1, BRAF, RAF1, CHUK
27Chronic myeloid leukemia2022.0PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
28Immune response ICOS pathway in T-helper cell1021.8PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
29IL-2 Pathway3621.3PIK3R3, PIK3R2, PIK3R1, MYC, RAF1, CHUK
30Immune response CD28 signaling1020.8PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
31Immune response_CD28 signaling4120.8PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
32Staphylococcus aureus infection2019.9SELP, CFB, CFD, CFH, CFI, ITGAL
33Immune response_Fc epsilon RI pathway4119.7PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, RELA
34Melanoma2019.7PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
35p53 Signaling3619.3PIAS1, BCL2, CHEK1, CHEK2, UBB, UBD
36Development_FGFR signaling pathway4119.1PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
37IL-3 Pathway3619.0PIK3R3, PIK3R2, PIK3R1, BRAF, RAF1, BCL2L1
38Development FGFR signaling pathway1018.9PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
39Development Thrombopoietin-regulated cell processes1018.9PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
40Immune response_IL-1 signaling pathway4118.8RELA, SERPINE1, MYD88, CHUK, UBB, UBC
41ErbB Family Pathway3618.4PIK3R3, PIK3R2, PIK3R1, NCK1, NCK2, BRAF
42Immune response_Oncostatin M signaling via MAPK in human cells4117.9RAF1, RAC1, LIFR, LDLR, CEBPB, ATF2
43Acute myeloid leukemia2017.6PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
44SUMO Pathway3617.5PIAS1, RANBP2, CHUK, ATF4, IL1A, IL1B
45all-trans-Retinoic Acid Mediated Apoptosis3617.5RARA, RARB, BID, CFLAR, IL28A, IL28B
46Development VEGF-family signaling1017.4PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
47CTL Mediated Apoptosis3617.4LIPF, BID, CD3D, CD3G, CD3E, GZMB
48Development_VEGF-family signaling4117.2PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
49Immune response_ICOS pathway in T-helper cell4115.8PIK3CB, PIK3CD, PIK3CA, PIK3CG, LAT, CD3D
50EGFR Inhibitor Pathway, Pharmacodynamics3412.4HRAS, NRAS, KRAS, SHC3, STAT2, STAT5A

Compounds for genes affiliated with Hepatitis

Sources:
32Novoseek , 42Tocris Bioscience, 34PharmGKB, 9DrugBank, 18HMDB
See all sources

Compounds related to hepatitis according to GeneDecks:

(show top 50)    (show all 482)
idCompoundScoreTop Affiliating Genes
1serine32 166.4PIK3CB, PIK3CD, PIK3CA, PIK3R1, PIAS1, PIK3CG
2estrogen32 94.9PIK3CB, PIK3R1, PIAS1, COG2, KLF6, NCL
3cyclosporin a32 42 71.2PIK3CA, PIK3C2A, PIK3CG, PIN1, COG2, CNTN2
4cisplatin32 34 9 9 72.7PIK3CA, PIK3C2A, REV3L, CNR2, KITLG, VTN
5heparin32 9 18 9 61.2PIK3CA, PIK3C2A, PIK3CG, LRP1, COG2, NCAM1
6phospholipid32 41.2PIK3R1, LRP8, COG2, VWF, SFTPC, SFTPD
7sb 20358032 42 41.6GCG, RB1, SELE, SETD2, VIM, BSG
8ly29400232 40.5PIK3CB, PIK3CA, PIK3R1, PIK3C2A, PIK3CG, RETN
9etoposide32 42 9 9 42.0PIK3CB, PIK3CA, PIK3R1, PIK3CG, CNTN2, PCNA
10herbimycin a32 42 38.6PIK3CG, KITLG, VTN, SELE, SELL, VCAM1
11rapamycin32 42 37.4PIK3CG, PIN1, PIM1, SGK1, KIT, KITLG
12thyroxine32 18 36.4PIK3C2A, COG2, REN, RETN, VWF, PCNA
13phosphatidylcholine32 34.2PIK3CB, LRAT, CNR1, SFTPC, SFTPD, PCTP
14p00232 29.5RETN, KIT, RB1, RBP4, BRAF, LPA
15celecoxib32 42 34 9 18 9 30.1PIK3R1, PIK3CG, REN, PCNA, VEGFA, BIRC5
16ag 147832 24.4PIK3CA, PIK3CG, SERPINE1, RAF1, BAK1, JUN
17nucleoside32 23.6KITLG, BPHL, BIRC5, CMPK1, CHEK1, UCK2
18bortezomib32 9 9 25.6SETD2, VEGFA, VCP, MYC, BID, BIRC5
19gefitinib32 34 9 9 26.4PIK3CA, PIK3CG, KIT, SFTPD, GCG, SELP
20daunorubicin32 9 9 25.1RELA, KITLG, LPO, MYC, RAF1, BIRC5
21pge132 22.9PIK3C2A, PDE3B, VWF, SELL, SERPINE1, VIP
22rifampicin32 22.2SERPINA7, NAT2, UGT1A, UGT1A1, UGT1A6, CD1B
23infliximab32 9 9 24.1SELE, VEGFA, ZFP36, BGLAP, BAK1, LBR
24sialic acid32 22.0NCAM1, RBP4, SELL, SERPINA7, SERPINF2, SERPINA6
25metformin32 34 9 9 24.9PIK3CA, PIK3CG, COG2, RETN, CNR1, VWF
26corticosterone32 18 22.9CNR1, PCK2, GCG, SERPINA7, SERPINA6, VIP
27anisomycin32 42 9 9 24.4PIK3CG, MYC, RAF1, BDNF, LDLR, MTOR
28guanidine hydrochloride32 21.3CNTF, VWF, SERPINA3, LPL, VDAC1, BMP4
29triiodothyronine32 21.0PIK3C2A, COG2, NCOR2, PCK2, RBP4, SERPINA7
30erythromycin32 9 9 23.0PIK3C2A, VIP, VCAM1, BCL2L1, UGT1A, MSRA
31linoleic acid32 18 21.9LPL, SCD, LDLR, UCP2, LCAT, MTTP
32valproic acid32 34 9 18 9 24.8COG2, NCAM1, KITLG, BTD, VCL, MYCN
33galactose32 20.5NCAM1, GC, SELL, CLEC12A, CLEC10A, CLEC4M
34pravastatin32 34 9 18 9 24.5PIK3C2A, COG2, SELE, SELP, SERPINE1, LPA
35oleic acid32 9 18 9 23.4LRP1, PCK2, GCG, GC, SERPINA7, LPA
36cytosine32 18 21.3CNTN2, MYB, RAD51, RASSF1, PAX5, LCP1
37menadione32 9 18 9 23.2VKORC1, BGLAP, MTHFR, XDH, CDK2, CDK4
38purine32 18 21.0NCAM1, UMPS, MUC1, UCP2, LBR, MTAP
39fluvastatin32 34 9 9 22.8PIK3C2A, COG2, VWF, SELP, SERPINE1, LPL
40epoxide32 19.5GC, SERPINA3, VKORC1, NAT1, NAT2, UGT1A
41propranolol32 34 9 18 9 23.4REN, VIP, LIPE, SCT, CHGA, UGT1A9
42glycosaminoglycan32 19.2LRP1, SGSH, VTN, SERPINC1, SERPIND1, NAGLU
43n-formylmethionyl-leucylphenylalanine32 19.1PIK3CG, NCF2, VTN, SELL, SELP, LCN2
44tetrapeptide32 18.9PIN1, VTN, RB1, SERPINB9, BIRC5, BCL2L1
45leptomycin b32 18.7CNTN2, GCKR, GCK, RANBP2, BIRC5, LGALS3
46phosphoserine32 18 19.4PIN1, CNTN2, GCA, VCL, RAF1, BCR
47dutp32 17.7PCNA, BIRC5, CLU, PARP1, BCL2, BCL2L1
48carbamazepine32 34 9 9 20.3COG2, SERPINA7, NAGLU, SCN1A, UGT1A, CD36
49chelerythrine32 17.0PIK3CG, KCNJ5, P2RX7, CFLAR, CDKN3, FOS
50budesonide32 42 9 9 17.0KITLG, SFTPD, BGLAP, CD36, IL5RA, ANXA1

GO Terms for genes affiliated with Hepatitis

Sources:
12Gene Ontology
See all sources

Cellular components related to hepatitis according to GeneDecks:

(show all 16)
idNameGO IDScoreTop Affiliating Genes
1cytoplasmGO:005737157.7ZNF638, ZNF318, PIAS3, PIAS4, PIK3R5, PIK3C2A
2plasma membraneGO:005886149.4PIK3CD, PIK3R1, PIK3C2A, PIK3CG, PIM1, LRP8
3cytosolGO:005829128.9PI4KA, PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2
4extracellular regionGO:005576104.0LRP8, NCAM1, PDCD1LG2, RETN, KITLG, KIRREL3
5extracellular spaceGO:00561593.2REN, CNTF, KIT, KITLG, VTN, SFRP1
6integral to plasma membraneGO:00588776.0LRMP, LRP1, LRRC32, NCR1, NCR2, NCR3
7nucleoplasmGO:00565457.4ZNF638, PIAS1, PIN1, RFC5, NCOA3, NCOA6
8mitochondrionGO:00573950.6SGK1, KIF1B, KIAA0101, PC, PCK2, GCK
9membraneGO:01602042.9PIK3R5, PIK3CG, SH2D3C, PDE3B, REN, CNTNAP2
10endoplasmic reticulum membraneGO:00578939.6PIGA, LRMP, LRAT, SGK1, RDH11, VKORC1
11cell surfaceGO:00998636.0NCAM1, CNTN2, CNTNAP2, SFRP1, SFRP4, PCSK9
12external side of plasma membraneGO:00989733.0NCAM1, KIT, VWF, BTLA, SELL, SELP
13perinuclear region of cytoplasmGO:04847131.9PI4KB, LRAT, PCSK9, VPS4A, GC, SELE
14membrane raftGO:04512121.8SELE, BSG, BST2, RAB5A, BCL10, SDC4
15platelet alpha granule lumenGO:03109317.9VWF, SERPINF2, SERPINA1, SERPINE1, SERPING1, VEGFA
16nucleusGO:005634INFZNF638, ZNF267, ZNF167, ZNF318, PIK3CB, PIAS2

Biological processes related to hepatitis according to GeneDecks:

(show top 50)    (show all 87)
idNameGO IDScoreTop Affiliating Genes
1signal transductionGO:00716575.6PI4KA, PIK3CB, PIK3CD, PI4KB, LRP8, SH2B2
2immune responseGO:00695558.5RFX1, NCR3, PDCD1LG2, CNR2, KIR2DS5, KIR2DL1
3apoptotic processGO:00691553.5PIM1, PDCD1, PDCD6IP, SGK1, KIF1B, PCSK9
4positive regulation of transcription from RNA polymerase II promoterGO:04594452.4PIAS2, KLF15, KLF2, KLF6, RFX3, NCK1
5virus-host interactionGO:01904846.4PIK3R1, PDCD6IP, RELA, RB1, RBCK1, SEPT6
6gene expressionGO:01046742.2NCOR2, PCBP1, PCBP2, SERPINE1, VDR, MYC
7positive regulation of transcription, DNA-dependentGO:04589340.3PIAS2, PIAS1, KLF2, KLF6, RFX3, NCOA3
8response to drugGO:04249338.9NCF2, REN, SFRP1, SEMA3C, SERPINA7, VEGFC
9cell adhesionGO:00715535.6NCAM1, CNTN2, CNTNAP2, KIRREL2, KITLG, VWF
10negative regulation of cell proliferationGO:00828534.7NCK2, SFRP1, SFRP4, VHL, VDR, MYOCD
11cell-cell signalingGO:00726734.6VIPR2, BST2, NAMPT, S100A9, XCL1, CGA
12response to virusGO:00961531.7PCBP2, BST2, MYD88, CLU, BECN1, BECN1P1
13anti-apoptosisGO:00691630.9PIK3CA, RELA, GCLC, SERPINB9, SEMA4D, NAIP
14cell surface receptor signaling pathwayGO:00716630.3BSG, BRD8, MYD88, LILRA1, LILRB5, LIFR
15protein phosphorylationGO:00646830.0PIK3CD, PIM1, SGK1, VRK1, BRAF, RARA
16G-protein coupled receptor signaling pathwayGO:00718629.1PIK3CB, PIK3R5, PIK3CG, GCG, VIP, VIPR1
17xenobiotic metabolic processGO:00680527.0GCLC, NAT1, NAT2, PAPSS1, PAPSS2, UGT1A1
18carbohydrate metabolic processGO:00597526.2SGSH, PC, PCK2, PCK1, GCKR, GCK
19nerve growth factor receptor signaling pathwayGO:04801125.6PIK3CB, PIK3CA, PIK3R2, PIK3R1, RELA, BRAF
20response to lipopolysaccharideGO:03249625.4NCF2, CNR1, CNR2, SFTPC, SELE, SELP
21positive regulation of apoptotic processGO:04306525.4PIAS4, CNR1, SFRP1, SFRP4, BMP4, RARB
22cellular nitrogen compound metabolic processGO:03464125.1PCBD1, GCLC, NAGS, BHMT, PAH, BBOX1
23regulation of immune responseGO:05077623.7KIR3DL2, KIR2DL1, KIR2DL3, KIR2DL4, KIR3DL1, KIR2DS2
24transcription initiation from RNA polymerase II promoterGO:00636723.3NCOA6, NCOR2, SERPINE1, VDR, MYC, RARA
25lipid metabolic processGO:00662923.3LRP8, PC, LPA, LPIN2, LPL, BMP1
26type I interferon-mediated signaling pathwayGO:06033723.3USP18, MX1, MX2, XAF1, JAK1, ISG15
27response to organic cyclic compoundGO:01407021.9NCF2, SFRP1, SELP, SERPINA1, BMP4, LEF1
28insulin receptor signaling pathwayGO:00828621.8PIK3CB, PIK3CA, PIK3R3, PIK3R2, PIK3R1, PIK3C2A
29platelet degranulationGO:00257621.6VWF, SELP, SERPINF2, SERPINA1, SERPINE1, SERPING1
30agingGO:00756821.4NCF2, CNR1, SERPINA7, SERPINF1, VDR, VCAM1
31epidermal growth factor receptor signaling pathwayGO:00717321.3PIK3CA, PIK3R1, PIK3C2A, NCK2, RAF1, CLTC
32fibroblast growth factor receptor signaling pathwayGO:00854321.1PIK3CA, PIK3R1, BRAF, RAF1, CHUK, YWHAB
33T cell receptor signaling pathwayGO:05085220.7PIK3CB, PIK3CD, PIK3CA, PIK3R2, PIK3R1, NCK1
34response to ethanolGO:04547120.6CNR1, RBP4, BGLAP, BCL2, CHAT, BAK1
35glucose metabolic processGO:00600620.5PIK3CA, PC, PCK2, PCK1, MYC, USF1
36positive regulation of peptidyl-tyrosine phosphorylationGO:05073119.7LRP8, KITLG, VTN, SEMA4D, VEGFA, LIF
37toll-like receptor 4 signaling pathwayGO:03414219.5RELA, MYD88, CHUK, UBB, UBC, ATF2
38cellular defense responseGO:00696819.1NCF2, NCR1, NCR2, RELA, KIR2DS3, KIR3DL2
39positive regulation of angiogenesisGO:04576619.1SERPINE1, VEGFA, RAMP2, UTS2, KDR, CHI3L1
40cellular response to mechanical stimulusGO:07126018.9SFTPC, BNIP3, MYD88, BCL10, CHEK1, BAD
41toll-like receptor 3 signaling pathwayGO:03413818.6RELA, CHUK, UBB, UBC, ATF2, JUN
42TRIF-dependent toll-like receptor signaling pathwayGO:03566618.6RELA, CHUK, UBB, UBC, ATF2, JUN
43positive regulation of ERK1 and ERK2 cascadeGO:07037418.3GCG, SERPINF2, BRAF, BMP4, BMPER, KDR
44cholesterol homeostasisGO:04263217.6PCSK9, MYLIP, LIPG, LIPC, SCARB1, LDLR
45phosphatidylinositol-mediated signalingGO:04801517.5PI4KA, PIK3CB, PIK3CA, PIK3R2, PIK3R1, PIK3C2A
46cellular response to insulin stimulusGO:03286917.4PDE3B, PCSK9, GCK, USF1, PAK1, PARP1
47glucose homeostasisGO:04259317.3PDE3B, PCK1, GCK, RBP4, SERPINE1, USF1
48glucose transportGO:01575816.3KLF15, GCKR, GCK, SEH1L, RANBP2, RAE1
49hexose transportGO:00864514.7GCKR, GCK, SEH1L, RANBP2, RAE1, TPR
50regulation of glucose transportGO:01082714.1GCKR, GCK, SEH1L, RANBP2, RAE1, TRIB3

Molecular functions related to hepatitis according to GeneDecks:

(show all 17)
idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:005515233.1PI4KA, PIK3CB, PIGA, PIK3CD, PIAS2, PIK3CA
2protein homodimerization activityGO:04280344.3NCOA6, KIT, VWF, SFTPC, RCHY1, GCA
3cytokine activityGO:00512535.6CNTF, KITLG, NAMPT, VEGFA, BMP1, BMP10
4identical protein bindingGO:04280235.5RELA, CNTN2, SFRP1, PCBD1, PCSK9, PCNA
5receptor bindingGO:00510234.9NCK1, REN, CNTFR, CNTNAP2, RCHY1, GCG
6receptor activityGO:00487230.0LRP1, KIR2DL1, KIR2DL3, BTLA, SEMA3C, SEMA4D
7protein heterodimerization activityGO:04698229.2GCA, NAE1, BRAF, VEGFA, BNIP3, VAPA
8enzyme bindingGO:01989928.7PIAS3, PIAS1, RFC5, NCOA6, CNTNAP2, PCBP2
9growth factor activityGO:00808327.2CNTF, KITLG, VEGFA, VEGFC, BMP1, BMP10
10protein kinase bindingGO:01990126.3RELA, VIM, LIPE, USF1, ZFP36, PAK1
11transcription factor bindingGO:00813423.7PIM1, RELA, RB1, NAB2, VHL, MYC
12transmembrane signaling receptor activityGO:00488823.4LRP8, NCR2, KIR2DL4, KIR2DS2, KIR2DS1, SELE
13heme bindingGO:02003722.7LPO, BACH1, MPO, JAK2, FECH, FADS1
14heparin bindingGO:00820120.9VTN, SFRP1, SELL, SELP, SERPINC1, SERPINA5
15electron carrier activityGO:00905520.9NCF2, SDHB, P4HB, XDH, ASPH, GSR
16chemokine activityGO:00800918.6CKLF, XCL1, IL8, CCL8, CCL4, CCL15
17ATP bindingGO:005524INFPI4KA, PIK3CB, PIK3CD, PIK3CA, PIK3C2A, PI4KB

Sources for Hepatitis

2CDC
11FMA
18HMDB
19ICD9CM
20KEGG
24MeSH
25MGI
27NCIt
28NDF-RT
31NINDS
32Novoseek
33OMIM
35PubMed
36QIAGEN
43UMLS