MCID: HPT021
MIFTS: 64

Hepatitis malady

Gastrointestinal diseases, Liver diseases, Infectious diseases, Rare diseases, Immune diseases categories

Summaries for Hepatitis

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Sources:
35MedlinePlus, 66Wikipedia, 34MalaCards
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MedlinePlus:35 Your liver is the largest organ inside your body. it helps your body digest food, store energy, and remove poisons. hepatitis is an inflammation of the liver. viruses cause most cases of hepatitis. the type of hepatitis is named for the virus that causes it; for example, hepatitis a, hepatitis b or hepatitis c. drug or alcohol use can also cause hepatitis. in other cases, your body mistakenly attacks healthy cells in the liver. some people who have hepatitis have no symptoms. others may have loss of appetite nausea and vomiting diarrhea dark-colored urine and pale bowel movements stomach pain jaundice, yellowing of skin and eyes some forms of hepatitis are mild, and others can be serious. some can lead to scarring, called cirrhosis, or to liver cancer. sometimes hepatitis goes away by itself. if it does not, it can be treated with drugs. sometimes hepatitis lasts a lifetime. vaccines can help prevent some viral forms.

MalaCards: Hepatitis, also known as acute hepatitis, is related to hepatitis b and hepatitis c. An important gene associated with Hepatitis is HAVCR1 (hepatitis A virus cellular receptor 1). The drugs astragalus preparation and milk thistle extract have been mentioned in the context of this disorder. Affiliated tissues include liver, t cells and kidney.

Wikipedia:66 Hepatitis (plural: hepatitides) is a medical condition defined by the inflammation of the liver and... more...

Aliases & Classifications for Hepatitis

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Sources:
9Disease Ontology, 11DISEASES, 46Novoseek, 35MedlinePlus, 32LifeMap Discoveryā„¢, 63UMLS, 59SNOMED-CT, 28ICD9CM, 26ICD10
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Classifications:



Aliases & Descriptions:

hepatitis 9 11 46 35 32 63
acute hepatitis 9 63
acute and subacute liver necrosis nos 9
acute and subacute necrosis of liver 9
acute and subacute liver necrosis 9
acute/subac. necrosis of liver 9
hepatitis, chronic persistent 63
chronic persistant hepatitis 9
hepatitis, chronic 63
hepatitis, animal 63
chronic hepatitis 9
hepatitis chronic 46
animal hepatitis 9


Related Diseases for Hepatitis

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Sources:
18GeneCards, 19GeneDecks
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Diseases in the Hepatitis C family:

Autoimmune Hepatitis Hepatitis B
Hepatitis D Hepatitis a
Hepatitis E hepatitis
Viral Hepatitis Hepatitis C Virus

Diseases related to Hepatitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 1603)
idRelated DiseaseScoreTop Affiliating Genes
1hepatitis b32.3LAMTOR5, RSF1
2hepatitis c11.5
3hepatitis c virus11.4
4viral hepatitis11.1
5hepatitis a11.1
6autoimmune hepatitis11.1
7hepatitis b virus infection11.1
8hepatocellular carcinoma11.1
9hepatic encephalopathy11.0
10hepatitis e11.0
11alcoholic hepatitis11.0
12hepatic coma11.0
13hepatitis d10.9
14liver disease10.9
15cryoglobulinemia10.9
16liver cirrhosis10.8
17congenital hepatic fibrosis10.8
18insulin resistance10.8
19granulomatous hepatitis10.8
20porphyria10.7
21glomerulonephritis10.7
22adenoma10.7
23angiomyolipoma10.7
24pancreatitis10.7
25obesity10.7
26hepatic angiomyolipoma10.7
27thyroiditis10.7
28tuberculosis10.7
29hemangioendothelioma10.7
30hypertension10.7
31primary biliary cirrhosis10.6
32porphyria cutanea tarda10.6
33hepatic vein thrombosis10.6
34cholestasis10.6
35drug-induced hepatitis10.6
36cholangiocarcinoma10.6
37portal hypertension10.6
38ischemia10.6
39fatty liver disease10.6
40hemangioma10.6
41nonalcoholic steatohepatitis10.6
42epithelioid hemangioendothelioma10.6
43hepatic tuberculosis10.6
44endotheliitis10.6
45membranoproliferative glomerulonephritis10.5
46cholangitis10.5
47colorectal cancer10.5
48fulminant viral hepatitis10.5
49diabetes mellitus10.5
50acute liver failure10.5

Graphical network of the top 20 diseases related to Hepatitis:



Diseases related to hepatitis

Symptoms for Hepatitis

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Drugs & Therapeutics for Hepatitis

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 32LifeMap Discoveryā„¢, 63UMLS, 42NDF-RT
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Approved drugs:

Search CenterWatch for Hepatitis

Drug clinical trials:

Search ClinicalTrials for Hepatitis

Search NIH Clinical Center for Hepatitis

Search CenterWatch for Hepatitis

Inferred drug relations via UMLS63/NDF-RT42:

Cell-based therapeutics:


LifeMap Discovery
The database of embryonic development, stem cell research and regenerative medicine
Read about Hepatitis cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Hepatitis:
Promethera
Embryonic/Adult Cultured Cells Related to Hepatitis:
Adult liver progenitor cells, PMIDs: 22525602, 23211283, 19091822, 24142276, 22900053

Genetic Tests for Hepatitis

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Anatomical Context for Hepatitis

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Sources:
34MalaCards
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MalaCards organs/tissues related to Hepatitis:

34
Liver, T cells, Kidney, Testes, Brain, Thyroid, B cells, Bone, Endothelial, Bone marrow, Monocytes, Skin, Heart, Colon, Eye, Lung, Nk cells, Pancreas, Breast, Myeloid, Lymph node, Prostate, Ovary, Pituitary, Cortex, Spleen, Smooth muscle, Fetal liver, Spinal cord, Salivary gland, Pancreatic islet, Whole blood, Small intestine, Tongue, Hypothalamus, Adrenal cortex, Cerebellum, Adipocyte, Skeletal muscle, Prefrontal cortex, Globus pallidus, Thalamus, Thymus, Cingulate cortex, Testis, Trachea, Placenta, Adrenal gland

Animal Models for Hepatitis or affiliated genes

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Publications for Hepatitis

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Sources:
53PubMed
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Articles related to Hepatitis:

(show top 50)    (show all 22134)
idTitleAuthorsYear
1
Health related quality of life in Iranian hemodialysis patients with viral hepatitis: changing epidemiology. (24032050)
2013
2
Hashimoto's thyroiditis concomitant with sequential autoimmune hepatitis, chorea and polyserositis: a new entity of autoimmune polyendocrine syndrome? (23318858)
2013
3
Reply to: Mother-to-infant transmission of hepatitis B virus infection: significance of maternal viral load and strategies for intervention. (23665186)
2013
4
Septic bursitis, a potential complication of protease inhibitor use in hepatitis C virus. (23413416)
2013
5
Fatal Hepatic Hemorrhage from Peliosis Hepatis with X-linked Myotubular Myopathy: A Case Report. (24172586)
2013
6
Infectious mononucleosis hepatitis; an unwelcome present for Father Christmas. (23732134)
2013
7
Zoonotic transmission of hepatitis E virus in industrialized countries. (24177295)
2013
8
Hepatitis C virus clearance correlates with HLA-DR expression on proliferating CD8+ T-cells in immune-primed chimpanzees. (24123114)
2013
9
Oral fluid and hepatitis A, B and C: a literature review. (22188507)
2012
10
Hepatitis B virus infection and fatty liver in the general population. (22027575)
2012
11
Relationships between tumour necrosis factor-I+, interleukin-12B and interleukin-10 gene polymorphisms and hepatitis B in Chinese Han haemodialysis patients. (22070668)
2012
12
Hepatic hemodynamics in 24 patients with nodular regenerative hyperplasia and symptomatic portal hypertension. (22554152)
2012
13
Identifications of polyphyletic variants in acute hepatitis suggest an underdiagnosed circulation of hepatitis E virus in Argentina. (21795113)
2011
14
Multiple cerebral arterial stenosis associated with hepatitis B virus infection. (21519526)
2011
15
Minimal hepatic encephalopathy is associated with falls. (20978484)
2011
16
Growth retardation, impaired triacylglycerol catabolism, hepatic steatosis, and lethal skin barrier defect in mice lacking comparative gene identification-58 (CGI-58). (20023287)
2010
17
Another cause of autoimmune hepatitis. (20578154)
2010
18
Chorioamnionitis induced hepatic inflammation and disturbed lipid metabolism in fetal sheep. (20717072)
2010
19
Hepatic and renal failure after anterior myocardial infarction induced apical ventricular septal defect. (21274286)
2010
20
Solitary hepatic lymphangioma in a 22-day-old infant. (19635291)
2009
21
Hepatic IL-17 responses in human and murine primary biliary cirrhosis. (19101114)
2009
22
Recurrence of autoimmune disease, primary sclerosing cholangitis, primary biliary cirrhosis, and autoimmune hepatitis after liver transplantation. (19876939)
2009
23
Polymorphism of OAS-1 determines liver fibrosis progression in hepatitis C by reduced ability to inhibit viral replication. (19515215)
2009
24
Morphological and functional features of hepatic cyst epithelium in autosomal dominant polycystic kidney disease. (18202196)
2008
25
Pregnane X receptor activators inhibit human hepatic stellate cell transdifferentiation in vitro. (16831602)
2006
26
Severe hypercholesterolemia associated with decreased hepatic triglyceride lipase activity and pseudohyponatremia in patients after allogeneic stem cell transplantation. (16298832)
2005
27
Interferon-alpha suppresses liver cell proliferation in patients with chronic hepatitis C virus infection. (16108765)
2005
28
Epigallocatechin-3-gallate, a polyphenol component of green tea, suppresses both collagen production and collagenase activity in hepatic stellate cells. (16142404)
2005
29
Hepatic angiomyolipoma: identification of an efferent vessel to be hepatic vein by contrast-enhanced harmonic ultrasound. (16177023)
2005
30
Mutations in human CPO gene predict clinical expression of either hepatic hereditary coproporphyria or erythropoietic harderoporphyria. (16159891)
2005
31
Elevated circulating adiponectin levels in liver cirrhosis are associated with reduced liver function and altered hepatic hemodynamics. (15010338)
2004
32
A case of autoimmune hepatitis and autoimmune hemolytic anemia following hepatitis A infection. (14655068)
2003
33
Similar increased serum dipeptidyl peptidase IV activity in chronic hepatitis C and other viral infections. (12727530)
2003
34
Porphyria cutanea tarda: multiplicity of risk factors including HFE mutations, hepatitis C, and inherited uroporphyrinogen decarboxylase deficiency. (11855561)
2002
35
Hepatitis B virus X protein associated with UV-DDB1 induces cell death in the nucleus and is functionally antagonized by UV-DDB2. (12151405)
2002
36
Interferon-alpha2a/ribaviran versus interferon-alpha2a alone for the retreatment of hepatitis C patients who relapse after a standard course of interferon. (11346153)
2001
37
Lack of a role of the interferon-stimulated response element-like region in interferon alpha -induced suppression of Hepatitis B virus in vitro. (11106638)
2001
38
Nutritive value of protein from sea urchin, and its effects on intestinal leucine aminopeptidase and intestinal and hepatic gamma-glutamyltranspeptidase. (11400470)
2001
39
N-acetylcysteine in acute hepatic failure (non-paracetamol-induced). (10919033)
2000
40
Hepatic glutamine transport and metabolism. (9559051)
1998
41
Gene expression of endothelin-1 and ET(A) and ET(B) receptors in human cirrhosis: relationship with hepatic hemodynamics. (9647333)
1998
42
Serious hepatitis A: an analysis of patients hospitalized during an urban epidemic in the United States. (9441570)
1998
43
Antibodies to P450IID6, SLA, PDH-E2 and BCKD-E2 in Japanese patients with chronic hepatitis. (9504898)
1997
44
Acute hepatitis, interstitial nephritis, and eosinophilia. (7872595)
1995
45
Diversity of quasispecies in various disease stages of chronic hepatitis C virus infection and its significance in interferon treatment. (7541387)
1995
46
Hepatitis C virus associated membranous glomerulonephritis. (8556829)
1995
47
Renal-hepatic-pancreatic dysplasia and its variants. (1741971)
1991
48
Improved outcome of paracetamol-induced fulminant hepatic failure by late administration of acetylcysteine. (1972496)
1990
49
Primary type 1 hyperlipoproteinemia: significance of lipoprotein lipase and hepatic triglyceride lipase activity in heterozygotes of patients with familial lipoprotein lipase deficiency. (6827414)
1983
50
Plasmapheresis with albumin as main substitute in acute hepatic coma. (5010510)
1972

Variations for Hepatitis

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Expression for genes affiliated with Hepatitis

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hepatitis

Search GEO for disease gene expression data for Hepatitis.

Pathways for genes affiliated with Hepatitis

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Compounds for genes affiliated with Hepatitis

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GO Terms for genes affiliated with Hepatitis

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Products for genes affiliated with Hepatitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Hepatitis

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet