MCID: HPT016
MIFTS: 62

Hepatitis B

Categories: Skin diseases, Infectious diseases, Liver diseases, Genetic diseases, Rare diseases, Gastrointestinal diseases, Immune diseases

Aliases & Classifications for Hepatitis B

MalaCards integrated aliases for Hepatitis B:

Name: Hepatitis B 38 12 52 41 42 14 69
Hepatitis B, Chronic 42 69
Hepatitis B Infection 12
Chronic Hepatitis B 12
Hepatitis B Chronic 52
Serum Hepatitis 12
Hbv 45

Classifications:



External Ids:

Disease Ontology 12 DOID:2043
NCIt 47 C3097
UMLS 69 C0019163

Summaries for Hepatitis B

MedlinePlus : 41 your liver is the largest organ inside your body. it helps your body digest food, store energy, and remove poisons. hepatitis is an inflammation of the liver. one type, hepatitis b, is caused by the hepatitis b virus (hbv). hepatitis b spreads by contact with an infected person's blood, semen, or other body fluid. an infected woman can give hepatitis b to her baby at birth. if you get hbv, you may feel as if you have the flu. you may also have jaundice, a yellowing of skin and eyes, dark-colored urine, and pale bowel movements. some people have no symptoms at all. a blood test can tell if you have it. hbv usually gets better on its own after a few months. if it does not get better, it is called chronic hbv, which lasts a lifetime. chronic hbv can lead to cirrhosis (scarring of the liver), liver failure, or liver cancer. there is a vaccine for hbv. it requires three shots. all babies should get the vaccine, but older children and adults can get it too. if you travel to countries where hepatitis b is common, you should get the vaccine. nih: national institute of diabetes and digestive and kidney diseases

MalaCards based summary : Hepatitis B, also known as hepatitis b, chronic, is related to polyarteritis nodosa and lymphoma, and has symptoms including abdominal pain, constipation and diarrhea. An important gene associated with Hepatitis B is LAMTOR5 (Late Endosomal/Lysosomal Adaptor, MAPK And MTOR Activator 5), and among its related pathways/superpathways are Toll-like Receptor Signaling Pathway and RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways. The drugs Emtricitabine and Adefovir Dipivoxil have been mentioned in the context of this disorder. Affiliated tissues include liver, testes and t cells, and related phenotypes are embryo and mortality/aging

Disease Ontology : 12 A viral infectious disease that results_in inflammation located in liver, has material basis in Hepatitis B virus, which is transmitted_by sexual contact, transmitted_by blood transfusions, and transmitted_by fomites like needles or syringes. The infection has symptom fever, has symptom fatigue, has symptom loss of appetite, has symptom nausea, has symptom vomiting, has symptom abdominal pain, has symptom clay-colored bowel movements, has symptom joint pain, and has symptom jaundice.

Wikipedia : 72 Hepatitis B is an infectious disease caused by the hepatitis B virus (HBV) that affects the liver. It... more...

Related Diseases for Hepatitis B

Diseases in the Hepatitis family:

Hepatitis C Virus Autoimmune Hepatitis
Hepatitis B Hepatitis a
Hepatitis C Viral Hepatitis
Hepatitis D Hepatitis E

Diseases related to Hepatitis B via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 431)
id Related Disease Score Top Affiliating Genes
1 polyarteritis nodosa 31.4 ALB IFNG TNF
2 lymphoma 31.4 ALB IFNG TNF
3 hepatocellular carcinoma 30.5 AFP ALB F2 GGT1 GPT IFNA1
4 systemic lupus erythematosus 29.9 ALB IFNA1 IFNG MBL2 TNF
5 alopecia 29.8 ALB F2 GPT TNF
6 hepadnavirus infection 29.5 ALB F2 GPT IFNG TNF
7 toxoplasmosis 29.5 IFNA1 TNF
8 hemolytic-uremic syndrome 28.8 AFP ALB F2 GPT IFNA2 TNF
9 hepatitis b reinfection following liver transplantation 11.8
10 hepatitis d 11.7
11 hepatitis 11.6
12 gianotti crosti syndrome 11.2
13 liver disease 11.2
14 membranous nephropathy 11.1
15 acrodermatitis 11.1
16 hepatoblastoma 11.1
17 childhood hepatocellular carcinoma 11.1
18 male infertility 11.0 IFNA1 IFNA2
19 breast ductal adenoma 11.0 IFNA1 IFNA2
20 tracheal calcification 11.0 GPT MBL2 TNF
21 congenital dyserythropoietic anemia 10.9 ALB TNF
22 congenital nystagmus 10.9 IFNA1 IFNA2 TNF
23 pulmonary tuberculosis 10.9 IFNA1 IFNG TNF
24 sternal cleft 10.9 IFNG TNF
25 bladder sarcoma 10.8 ALB GPT TNF
26 bacterial gastritis 10.8 IFNA1 IFNG TNF
27 benign mammary dysplasia 10.8 ALB IFNA1 TNF
28 autoimmune polyglandular syndrome type 3 10.8 IFNG TNF
29 heart sarcoma 10.8 APOBEC3G IFNA1 IFNG TNF
30 colon adenocarcinoma 10.8 ALB IFNA1 TNF
31 tonsil cancer 10.8 ALB GPT IFNG
32 argyria 10.8 F2 GPT
33 rift valley fever 10.8 ALB IFNG TNF
34 neonatal jaundice 10.7 IFNA1 IFNG TNF
35 isolated growth hormone deficiency 10.7 ALB GPT IFNG
36 patent foramen ovale 10.7 ALB GPT SLC10A1
37 gastric ulcer 10.7 ALB IFNG TNF
38 opportunistic bacterial infectious disease 10.7 ALB IFNG TNF
39 mucocutaneous leishmaniasis 10.7 ALB IFNG TNF
40 maxillary sinusitis 10.7 F2 GPT IFNA2
41 ovarian brenner tumor 10.7 IFNA1 IFNA2 IFNG TNF
42 endometrial clear cell adenocarcinoma 10.7 ALB IFNG TNF
43 carotid artery dissection 10.7 GPT IFNA1 IFNA2 IFNG TNF
44 moderately severe hemophilia b 10.7 F2 IFNA1 TNF
45 nuchal bleb, familial 10.7 IFNA1 IFNA2
46 premature ovarian failure 12 10.7 ALB MBL2 TNF
47 cockayne syndrome 10.7 IFNG MBL2 TNF
48 non-hodgkin lymphoma, during pregnancy 10.7 ALB F2
49 esophageal candidiasis 10.7 IFNA2 IFNG TNF
50 goodpasture syndrome 10.7 IFNA1 IFNA2 IFNG MBL2 TNF

Graphical network of the top 20 diseases related to Hepatitis B:



Diseases related to Hepatitis B

Symptoms & Phenotypes for Hepatitis B

UMLS symptoms related to Hepatitis B:


abdominal pain, constipation, diarrhea, dyspepsia, fever, heartburn, icterus, nausea and vomiting, pruritus, gastrointestinal gas

MGI Mouse Phenotypes related to Hepatitis B:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 embryo MP:0005380 9.5 NR5A2 RARB TNF AIP DDX3X F2
2 mortality/aging MP:0010768 9.44 AFP AIP ALB DDB1 DDX3X F2

Drugs & Therapeutics for Hepatitis B

Drugs for Hepatitis B (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 524)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Emtricitabine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 143491-57-0 60877
2
Adefovir Dipivoxil Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 142340-99-6 60871
3
Entecavir Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 142217-69-4 153941
4
Peginterferon alfa-2a Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 198153-51-4 5360545
5
Aluminum hydroxide Approved Phase 4,Phase 3,Phase 2,Phase 1 21645-51-2
6
Neomycin Approved, Vet_approved Phase 4 1404-04-2 8378
7
Lamivudine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 134678-17-4 60825
8
Telbivudine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 3424-98-4 159269
9
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 83-43-2 6741
10
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-24-8 5755
11
Peginterferon alfa-2b Approved Phase 4,Phase 3,Phase 2,Phase 1 99210-65-8, 215647-85-1
12
Ribavirin Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 36791-04-5 37542
13
Ethiodized oil Approved Phase 4,Phase 2,Phase 3 8008-53-5
14
Benzocaine Approved Phase 4,Phase 2,Phase 3,Phase 1 1994-09-7, 94-09-7 2337
15
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 9552079 2713
16
Mycophenolate mofetil Approved, Investigational Phase 4 128794-94-5 5281078
17
Mycophenolic acid Approved Phase 4 24280-93-1 446541
18
Tacrolimus Approved, Investigational Phase 4,Phase 2,Phase 1 104987-11-3 445643 439492
19
Acarbose Approved, Investigational Phase 4 56180-94-0 441184
20
Metformin Approved Phase 4 657-24-9 14219 4091
21
Pioglitazone Approved, Investigational Phase 4 111025-46-8 4829
22
Pentoxifylline Approved, Investigational Phase 4 6493-05-6 4740
23
Thymalfasin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 62304-98-7
24 Simethicone Approved Phase 4,Phase 3
25
rituximab Approved Phase 4,Phase 3,Phase 2,Phase 1 174722-31-7 10201696
26
Efavirenz Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2 154598-52-4 64139
27
Zidovudine Approved Phase 4,Phase 2,Phase 1 30516-87-1 35370
28
Ritonavir Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 155213-67-5 392622
29
Lenograstim Approved Phase 4,Phase 1,Phase 2 135968-09-1
30
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22916-47-8 4189
31
Maraviroc Approved, Investigational Phase 4,Phase 3,Phase 2 376348-65-1 3002977
32
Ethanol Approved Phase 4,Phase 2,Phase 1 64-17-5 702
33
Ledipasvir Approved Phase 4,Phase 3,Phase 2,Early Phase 1 1256388-51-8 67505836
34
Sofosbuvir Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 1190307-88-0 45375808
35
chloroquine Approved, Vet_approved Phase 4,Phase 1 54-05-7 2719
36
Adalimumab Approved Phase 4 331731-18-1 16219006
37
Etanercept Approved, Investigational Phase 4 185243-69-0
38
Edetic Acid Approved, Vet_approved Phase 4,Phase 3,Phase 2 60-00-4, 62-33-9 6049
39
Iron Approved Phase 4,Phase 3,Phase 2,Phase 1 7439-89-6 23925
40
Acetaminophen Approved Phase 4,Phase 3,Phase 2 103-90-2 1983
41
Ibuprofen Approved Phase 4 15687-27-1 3672
42
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757
43
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
44
Levonorgestrel Approved, Investigational Phase 4 797-63-7, 17489-40-6 13109
45
Saquinavir Approved, Investigational Phase 4 127779-20-8 60787
46
Acetylcarnitine Approved, Investigational Phase 4,Phase 3 3040-38-8 1
47
Simeprevir Approved Phase 4,Phase 3,Phase 2,Phase 1 923604-59-5 66576988
48
Buprenorphine Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 3 52485-79-7 40400 644073
49
Diphenhydramine Approved Phase 4 58-73-1, 147-24-0 3100
50
Histamine Approved, Investigational Phase 4 75614-87-8, 51-45-6 774

Interventional clinical trials:

(show top 50) (show all 1998)

id Name Status NCT ID Phase Drugs
1 A Randomized,Parallel-group Clinical Trial of Hepatitis B Vaccine With Different Dosages and Schedules in Healthy Adults Unknown status NCT02203357 Phase 4
2 Adolescents' Response to Hepatitis B Vaccine Booster Dose Unknown status NCT01341275 Phase 4
3 Emtricitabine for Naive Chinese Pregnant Chronic Hepatitis B Patients Unknown status NCT02327702 Phase 4 Emtricitabine
4 Efficacy Optimizing Research of Chronic Hepatitis B Patients With Inadequate Response to NUC Therapy Unknown status NCT01341743 Phase 4 Entecavir;Entecavir, Adefovir;Entecavir, Adefovir
5 Hepatitis B Virus (HBV) Antibody (Anti-HBs) Booster Program for the Production of Hepatitis B Immune Globulin (HBIG) Unknown status NCT01311674 Phase 4
6 Pegasys Plus Entecavir Versus Entecavir Alone for Hepatitis Be Antigen-Positive Chronic Hepatitis B Unknown status NCT00597259 Phase 4 Pegasys plus Entecavir;Entecavir
7 Sustained Off-treatment Response After HBeAg Loss in Chronic Hepatitis B Patients Treated With Nucleos(t)Ide Analogues Unknown status NCT01911156 Phase 4 Continue NA treatment;Discontinue NA Treatment
8 Influence of Hepatic Steatosis on the Therapeutic Effect of Entecavir in Chronic Hepatitis B Patients Unknown status NCT01148576 Phase 4 entecavir;entecavir;essentiale + entecavir;Vitamin E + entecavir
9 Cellular Immunity in Adult Hepatitis B-vaccinated Serologic Non-responders Unknown status NCT01451801 Phase 4
10 Emtricitabine for Naive Child Chinese Chronic Hepatitis B Patients Unknown status NCT02327676 Phase 4 Emtricitabine
11 Effects of Short-term Atorvastatin Treatment on Vaccination Efficacy in Nonresponder Persons to Hepatitis B Vaccine Unknown status NCT01548326 Phase 4 Atorvastatin;placebo
12 Efficacy and Safety of S-adenosyl-L-methionine in Treatment of Chronic Hepatitis B Patients With Cholestasis Unknown status NCT01998620 Phase 4 Ademetionine 2;Ademetionine 1;Ademetionine 3
13 Antiviral Efficacy of the Combination Treatment With Poly IC and Entecavir for Chronic Hepatitis B Unknown status NCT02532413 Phase 4 Poly IC;Entecavir
14 Comparison of Telbivudine Plus Adefovir With Lamivudine Plus Adefovir for the Treatment of Lamivudine-resistant Chronic Hepatitis B at 52 Weeks: A Pilot Study Unknown status NCT01804387 Phase 4 telbivudine plus adefovir;lamivudine plus adefovir
15 Switch From Adefovir to Tenofovir in Chronic Hepatitis B for Suboptimal Response to Adefovir-based Combination Therapy Unknown status NCT01595633 Phase 4 Switching from adefovir (10mg/day) to tenofovir (300mg/day)
16 Efficacy and Safety of Entecavir Maleate Tablets in Chinese Patients With Hepatitis B Unknown status NCT01926288 Phase 4 Entecavir maleate tablets;blank Baraclude tablets;Blank maleate entecavir tablets;Baraclude tablets
17 Combination or Sequential Therapy of Peginterferon Alfa-2a and Entecavir for Patients With Chronic Hepatitis B Unknown status NCT01906580 Phase 4 Peg-IFNα-2a;Entecavir
18 Safety and Efficacy of Telbivudine on Liver Cirrhosis in Patients With Chronic Hepatitis B (CHB) Unknown status NCT01380951 Phase 4 telbivudine
19 Study of Effects and Safety Between Adefovir Dipivoxil Plus Polyene Phosphatidylcholine Versus Adefovir Dipivoxil Alone in Chronic Hepatitis B Patients Unknown status NCT01436539 Phase 4 Adefovir Dipivoxil and polyene phosphatidylcholine;Adefovir Dipivoxil
20 Lamivudine Extending Therapy in Chronic Hepatitis B Patients After 3-year of Oral Antiviral Agents Unknown status NCT02337127 Phase 4 Lamivudine
21 Prednisolone Priming Study in Patients With Chronic Hepatitis B Unknown status NCT00778596 Phase 4 Prednisolone;Placebo priming
22 Entecavir Plus Tenofovir Combination in Subjects With Multi-drug Resistant Chronic Hepatitis B Virus Infection Unknown status NCT01594905 Phase 4 Entecavir + Tenofovir (MDR group)
23 Pegylated Interferon Alfa-2b Plus Ribavirin in Chronic Hepatitis B and Delta Unknown status NCT00117533 Phase 4 pegylated IFN alfa-2b plus ribavirin
24 Entecavir and Pegasys Sequential Therapy Versus Pegasys for HBeAg Positive Chronic Hepatitis B Unknown status NCT00921180 Phase 4 Entecavir and peginterferon alfa-2a;Placebo and peginterferon
25 Entecavir and Pegasys Sequential Therapy Versus Pegasys for HBeAg Negative Chronic Hepatitis B Unknown status NCT00917761 Phase 4 Entecavir and peginterferon (Pegasys) (52 weeks);Peginterferon (Pegasys) (96 weeks);Peginterferon (Pegasys) (48 weeks)
26 Active Drug Comparative Trial to Evaluate the Antiviral Activity and Safety in Chronic Hepatitis B Patients Unknown status NCT02588937 Phase 4 EntecaBell ODT. 0.5mg;Baraclude Tab. 0.5mg
27 Efficacy of Antiviral Therapy After Radical Resection for Hepatitis B Virus-Related Hepatocellular Carcinoma Unknown status NCT00768157 Phase 4 antiviral treatment (lamivudine or entecavir)
28 Entecavir for Chronic Hepatitis B Patients With Persistently Normal ALT Unknown status NCT01833611 Phase 4 Entecavir;placebo
29 A Trial To Study The Effect Of Lamivudine In Adult Patients Who Suffer From Chronic Hepatitis B Alone Unknown status NCT00354653 Phase 4 LAMIVUDINE
30 Study to Evaluate the Non-inferiority of Cavir in HBeAg(+)Chronic Hepatitis B Patients Treated With Baraclude Unknown status NCT02523547 Phase 4 Cavir;Baraclude
31 Combination Hepatitis A and B Vaccine to Induce Immunity in Non-responders Unknown status NCT01126853 Phase 4
32 Synergistic Treatment for Hepatocellular Carcinoma (HCC) Using Transcatheter Arterial Chemoembolization (TACE) With Anti-hepatitis B Virus (Anti-HBV) Therapy Unknown status NCT01102335 Phase 4 Telbivudine
33 Efficacy of Telbivudine With or Without add-on Tenofovir According to Roadmap Strategy Compare With Entecavir Unknown status NCT01588912 Phase 4 Telbivudine;Tenofovir;Entecavir
34 Efficacy and Safety Study of Telbivudine to Prevent Perinatal Transmission Unknown status NCT00939068 Phase 4 Telbivudine
35 Antiviral Therapy in Hepatitis B Virus (HBV)-Related Advanced Liver Disease Patients Unknown status NCT00823550 Phase 4 Entecavir;Lamivudine
36 HBsAg Related Response Guided Therapy Unknown status NCT01456312 Phase 4 Peginterferon alfa-2a;Entecavir
37 A Clinical Evaluation on Traditional Chinese Medicine Diagnosis and Treatment Program Blocking and Reversing Hepatitis B-related Liver Fibrosis - a Randomized, Controlled, Double-blind, Multi-center Clinical Trial Unknown status NCT01965418 Phase 4 Fufang Biejia Ruangan Tablet;Placebo
38 Efficacy Optimizing Extension Study of Chronic Hepatitis B Patients With Inadequate Response to NUC Therapy Unknown status NCT01829685 Phase 4 Entecavir, Adefovir
39 Improved Prevention of Perinatal Hepatitis B Transmission Unknown status NCT01133184 Phase 4
40 Influence of Antiviral Treatment to the Long-Term Prognosis of Patients With Chronic HBV Infection Unknown status NCT00810524 Phase 4 lamivudine;Telbivudine;Enticavir;Adefovir Dipivoxil Tablets
41 EFFORT Extension Study Unknown status NCT01529255 Phase 4 telbivudine (ROADMAP);Telbivudine (Standard of Care)
42 Entecavir for Patients With Decompensated Hepatitis B Virus (HBV)-Related Cirrhosis Unknown status NCT00663182 Phase 4 Entecavir
43 A Trial Comparing Entacavir and Tenofovir in Patients With HBV Decompensated Cirrhosis Unknown status NCT02238860 Phase 4 Entacavir;Tenofovir
44 3E Extension Study Unknown status NCT01834508 Phase 4 oral entecavir 0.5mg daily and adefovir 10mg daily for 144 weeks
45 An Exploratory Study of RGT Strategy on Optimal NUC-experienced Patients Unknown status NCT02560649 Phase 4 Peginterferon alfa-2a plus Entecavir;Peginterferon alfa-2a plus Lamivudine;Peginterferon alfa-2a plus Adefovir;Peginterferon alfa-2a plus Tenofovir;Entecavir;Lamivudine;Adefovir;Tenofovir disoproxil
46 A Two-year Study of Telbivudine in HBeAg Negative Hepatitis Unknown status NCT01521975 Phase 4 Telbivudine, Adefovir dipivoxil
47 Antiviral Efficacy of Switching to ETV Plus TDF Unknown status NCT01597934 Phase 4 Group A (Zeffix, Sebivo, Hepsera);Group B (Baraclude, Viread)
48 Safety, Long Term Immunogenicity and Lot Consistency Study of Liquid Pentavalent Combination Vaccine Unknown status NCT00877357 Phase 4
49 TO Compare the Triple Drug Therapy and Dual Therapy . Unknown status NCT02075242 Phase 4 Mycophenolate Mofetil;Tacrolimus
50 Using Entecavir to Reduce Hepatitis in Highly Viremic HBV Patients During Anti-tuberculous Treatment Unknown status NCT01724723 Phase 4 entecavir (BARACLUDE®)

Search NIH Clinical Center for Hepatitis B

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Hepatitis B cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Hepatitis B:
Bone marrow-derived mesenchymal stem cells for treatment of liver failure
Embryonic/Adult Cultured Cells Related to Hepatitis B:
Bone marrow-derived mesenchymal stem cells (family)

Cochrane evidence based reviews: hepatitis b

Genetic Tests for Hepatitis B

Anatomical Context for Hepatitis B

MalaCards organs/tissues related to Hepatitis B:

39
Liver, Testes, T Cells, Kidney, Bone, B Cells, Skin

Publications for Hepatitis B

Articles related to Hepatitis B:

(show top 50) (show all 4566)
id Title Authors Year
1
Promoting effect of hepatitis B virus on the expressoin of phospholipase A2 group IIA. ( 28077172 )
2017
2
Hepatitis B and C in Tonkolili Province, Sierra Leone. ( 28952444 )
2017
3
Frequency and role of NKp46 and NKG2A in hepatitis B virus infection. ( 28328926 )
2017
4
Expression of microRNA let-7a positively correlates with hepatitis B virus replication in hepatocellular carcinoma tissues. ( 28440732 )
2017
5
Cell death biomarker M65 is a useful indicator of liver inflammation and fibrosis in chronic hepatitis B: A cross-sectional study of diagnostic accuracy. ( 28514295 )
2017
6
Variations in IL-1R1 Gene Influence Risk for Hepatitis B Virus Infection of Children in a Han Chinese population. ( 28027994 )
2017
7
Molecular characterization of AID-mediated reduction of hepatitis B virus transcripts. ( 28779685 )
2017
8
Efficacy and safety of entecavir versus lamivudine over 5 years of treatment: A randomized controlled trial in Korean patients with hepatitis B e antigen-negative chronic hepatitis B. ( 28946736 )
2017
9
Lack of Ser267Phe variant of sodium taurocholate cotransporting polypeptide among Moroccans regardless of hepatitis B virus infection status. ( 28125961 )
2017
10
Multiple small intestinal perforations in a patient with Hepatitis B Virus-associated Polyarteritis Nodosa. ( 28878877 )
2017
11
Genotypes and subgenotypes of hepatitis B virus circulating in an endemic area in Peru. ( 28948365 )
2017
12
Hypermethylation of the N-Myc Downstream-Regulated Gene 2 Promoter in Peripheral Blood Mononuclear Cells is Associated with Liver Fibrosis in Chronic Hepatitis B. ( 28202850 )
2017
13
Lamivudine, Entecavir, or Tenofovir Treatment of Hepatitis B Infection: Effects on Calcium, Phosphate, FGF23 and Indicators of Bone Metabolism. ( 28233741 )
2017
14
Early-age hepatocellular carcinoma associated with hepatitis B infection in South America. ( 28532694 )
2017
15
Origin and evolutionary dynamics of Hepatitis B virus (HBV) genotype E in Madagascar. ( 28081689 )
2017
16
Association of Mutations in Toll-like Receptor 2 Signaling Genes With Fulminant Form of Hepatitis B-Related Acute Liver Failure. ( 28329297 )
2017
17
Interferon induces interleukin 8 and bone marrow stromal cell antigen 2 expression, inhibiting the production of hepatitis B virus surface antigen from human hepatocytes. ( 28363866 )
2017
18
Italian consensus Guidelines for the management of hepatitis B virus infections in patients with rheumatoid arthritis. ( 28529116 )
2017
19
SOCS3 genetic variants and promoter hypermethylation in patients with chronic hepatitis B. ( 28179578 )
2017
20
Quantification of large and middle proteins of hepatitis B virus surface antigen (HBsAg) as a novel tool for the identification of inactive HBV carriers. ( 28951526 )
2017
21
Outcome of anti-thymocyte immunoglobulin plus cyclosporine A for severe aplastic anaemia with chronic hepatitis B virus infection. ( 28084534 )
2017
22
Diagnostic Value of the Methylation of Multiple Gene Promoters in Serum in Hepatitis B Virus-Related Hepatocellular Carcinoma. ( 28951629 )
2017
23
Evaluation of hepatitis C, hepatitis B, and HIV virus Serology pandemic in thalassemia patients of Shahid Mohammadi Hospital of Bandar Abbas, Iran. ( 28461879 )
2017
24
Hepatic expansion of virus-specific CD8(+)BTLA(+) T cells with regulatory properties in chronic hepatitis B virus infection. ( 27743606 )
2017
25
A Case of Primary Biliary Cirrhosis Mimicking Acute Hepatitis B in the Clinic, Republic of Korea. ( 28197333 )
2017
26
The regulatory role of IL-6R in hepatitis B-associated fibrosis and cirrhosis. ( 28953986 )
2017
27
Interplay between SIRT1 and hepatitis B virus X protein in the activation of viral transcription. ( 28242208 )
2017
28
Discovering potential serological biomarker for chronic Hepatitis B Virus-related hepatocellular carcinoma in Chinese population by MAL-associated serum glycoproteomics analysis. ( 28079114 )
2017
29
Hepatitis B virus induced cytoplasmic antineutrophil cytoplasmic antibody-mediated vasculitis causing subarachnoid hemorrhage, acute transverse myelitis, and nephropathy: a case report. ( 28366165 )
2017
30
Prevalence of hepatitis B and hepatitis C viral infections in various subtypes of B-cell non-Hodgkin lymphoma: confirmation of the association with splenic marginal zone lymphoma. ( 28362442 )
2017
31
Des-I^ carboxyprothrombin may not be a good biomarker for hepatocellular carcinoma in those chronically infected with hepatitis B virus with basal core promoter double mutations (T^{1762}, A^{1764}), a prospective study. ( 28085009 )
2017
32
Pityriasis rosea in a patient with retrovirus infection and a history of syphilis and positive results of infection with hepatitis A virus, hepatitis B virus and hepatitis C virus. ( 28670260 )
2017
33
Noninvasive Assessment of Liver Fibrosis Stage Using Ultrasound-Based Shear Wave Velocity Measurements and Serum Algorithms in Patients With Viral Hepatitis B: A Retrospective Cohort Study. ( 28039877 )
2017
34
Increased risk of hepatitis B virus reactivation in systemic lupus erythematosus patients receiving immunosuppressants: a retrospective cohort study. ( 28534427 )
2017
35
HMGB1-induced autophagy: a new pathway to maintain Treg cell function during chronic hepatitis B virus infection. ( 28082516 )
2017
36
The membrane-bound O-acyltransferase domain-containing 7 variant rs641738 increases inflammation and fibrosis in chronic hepatitis B. ( 28109005 )
2017
37
Hepatitis B virus core-related antigen levels predict progression to liver cirrhosis in hepatitis B carriers. ( 28914957 )
2017
38
Hepatitis B Virus-Hepatitis D Virus mother-to-child co-transmission: A retrospective study in a developed country. ( 28834623 )
2017
39
Liver fibrosis progression in patients with chronic hepatitis B: a prospective study with paired transient elastography. ( 28943521 )
2017
40
A Randomized Controlled Trial to Evaluate a Potential Hepatitis B Booster Vaccination Strategy Using Combined Hepatitis A and B Vaccine. ( 28060048 )
2017
41
Prevalence and risk factors for hepatitis B and C viruses in patients with leprosy. ( 28457830 )
2017
42
A collaborative study to establish the 3rd WHO International Standard for hepatitis B virus for nucleic acid amplification techniques. ( 28082100 )
2017
43
An ImmunoSignature test distinguishes Trypanosoma cruzi, hepatitis B, hepatitis C and West Nile virus seropositivity among asymptomatic blood donors. ( 28873423 )
2017
44
Rituximab administration in a patient with pemphigus vulgaris following reactivation of occult hepatitis B virus infection. ( 28633752 )
2017
45
Th17/Treg imbalance and increased interleukin-21 are associated with liver injury in patients with chronic severe hepatitis B. ( 28259000 )
2017
46
Diagnosis of coinfection by schistosomiasis and viral hepatitis B or C using 1H NMR-based metabonomics. ( 28763497 )
2017
47
Expression of P62 in hepatocellular carcinoma involving hepatitis B virus infection and aflatoxin B1 exposure. ( 28941211 )
2017
48
Prevalence and epidemiology of hepatitis D among patients with chronic hepatitis B virus infection: a report from Northern Spain. ( 27902514 )
2017
49
A Effects of interleukin-4 and interleukin-12B gene polymorphisms on hepatitis B virus vaccination. ( 28051794 )
2017
50
Matrix Metalloproteinase 9 Facilitates Hepatitis B Virus Replication through Binding with Type I Interferon (IFN) Receptor 1 To Repress IFN/JAK/STAT Signaling. ( 28122987 )
2017

Variations for Hepatitis B

Expression for Hepatitis B

Search GEO for disease gene expression data for Hepatitis B.

Pathways for Hepatitis B

GO Terms for Hepatitis B

Cellular components related to Hepatitis B according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.61 AFP ALB DDX3X F2 IFNA1 IFNA2
2 extracellular space GO:0005615 9.4 AFP ALB CPD DDB1 F2 GGT1

Biological processes related to Hepatitis B according to GeneCards Suite gene sharing:

(show all 13)
id Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 9.92 ALB DDB1 DDX3X LAMTOR5 RARB
2 innate immune response GO:0045087 9.91 APOBEC3G DDX3X IFNA1 IFNA2 MBL2
3 defense response to virus GO:0051607 9.76 APOBEC3G IFNA1 IFNA2 IFNG
4 response to virus GO:0009615 9.67 DDX3X IFNG LAMTOR5 TNF
5 positive regulation of viral genome replication GO:0045070 9.5 DDB1 DDX3X NR5A2
6 positive regulation of chemokine biosynthetic process GO:0045080 9.49 IFNG TNF
7 positive regulation of programmed cell death GO:0043068 9.48 RARB TNF
8 negative regulation of viral process GO:0048525 9.43 APOBEC3G MBL2
9 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.4 IFNG TNF
10 positive regulation of peptidyl-serine phosphorylation of STAT protein GO:0033141 9.33 IFNA1 IFNA2 IFNG
11 positive regulation of vitamin D biosynthetic process GO:0060557 9.26 IFNG TNF
12 negative regulation of growth of symbiont in host GO:0044130 9.13 IFNG MBL2 TNF
13 humoral immune response GO:0006959 8.92 IFNA1 IFNA2 IFNG TNF

Molecular functions related to Hepatitis B according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 8.92 IFNA1 IFNA2 IFNG TNF

Sources for Hepatitis B

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet