MCID: HPT063
MIFTS: 39

Hepatitis B Virus Infection malady

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Summaries for Hepatitis B Virus Infection

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MalaCards based summary: Hepatitis B Virus Infection is related to hepatitis b and hepatitis c. An important gene associated with Hepatitis B Virus Infection is IFNGR1 (interferon gamma receptor 1), and among its related pathways are PEDF Induced Signaling and Jak-STAT signaling pathway. The compounds peginterferon alfa-2b and peginterferon alfa-2a have been mentioned in the context of this disorder. Affiliated tissues include liver, t cells and b cells.

Description from OMIM:46 610424

Aliases & Classifications for Hepatitis B Virus Infection

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Hepatitis B Virus Infection, Aliases & Descriptions:

Name: Hepatitis B Virus Infection 46


Related Diseases for Hepatitis B Virus Infection

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Graphical network of the top 20 diseases related to Hepatitis B Virus Infection:



Diseases related to hepatitis b virus infection

Symptoms for Hepatitis B Virus Infection

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Clinical features from OMIM:

610424

Drugs & Therapeutics for Hepatitis B Virus Infection

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Drug clinical trials:

Search ClinicalTrials for Hepatitis B Virus Infection

Search NIH Clinical Center for Hepatitis B Virus Infection

Genetic Tests for Hepatitis B Virus Infection

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Anatomical Context for Hepatitis B Virus Infection

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MalaCards organs/tissues related to Hepatitis B Virus Infection:

32
Liver, T cells, B cells, Kidney, Testes, Bone, Monocytes, Nk cells, Bone marrow, Heart, Thyroid, Skin, Myeloid, Neutrophil

Animal Models for Hepatitis B Virus Infection or affiliated genes

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Publications for Hepatitis B Virus Infection

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Articles related to Hepatitis B Virus Infection:

(show top 50)    (show all 785)
idTitleAuthorsYear
1
Rare detection of occult hepatitis B virus infection in children of mothers with positive hepatitis B surface antigen. (25383543)
2014
2
Association of HLA-DQA1 gene rs9272346 polymorphism with clinical outcome of hepatitis B virus infection in ethnic Han population from Hubei]. (24510573)
2014
3
Occult hepatitis B virus infection in liver transplant patients in a Brazilian referral center. (25296362)
2014
4
Risk of hepatocellular carcinoma and cancers at other sites among patients diagnosed with chronic hepatitis B virus infection in Sweden. (24038002)
2014
5
microRNA expression in hepatitis B virus infected primary treeshrew hepatocytes and the independence of intracellular miR-122 level for de novo HBV infection in culture. (24314655)
2014
6
Reply to: Mother-to-infant transmission of hepatitis B virus infection: significance of maternal viral load and strategies for intervention. (23665186)
2013
7
The association between circulating oestradiol levels and severity of liver disease in males with hepatitis B virus infection. (23551989)
2013
8
NK cells: a double-edged sword in chronic hepatitis B virus infection. (23459859)
2013
9
Serum angiotensin-converting enzyme level as a marker of severity in HBeAg-negative chronic hepatitis B virus infection. (23884912)
2013
10
Sodium taurocholate cotransporting polypeptide mediates woolly monkey hepatitis B virus infection of Tupaia hepatocytes. (23596296)
2013
11
Prophylactic effect of lamivudine-based antiretroviral therapy on incident hepatitis B virus infection among HIV-infected patients. (23926178)
2013
12
Association between cytotoxic T-lymphocyte-associated antigen 4 +49A/G polymorphism and persistent hepatitis B virus infection in the Asian population: evidence from the current studies. (23725008)
2013
13
Perinatal transmission of hepatitis B virus infection in Ile-Ife, South Western, Nigeria. (24246595)
2013
14
Detection of occult hepatitis B virus infection among blood donors in Sudan. (23528527)
2013
15
Immune therapeutic strategies in chronic hepatitis B virus infection: virus or inflammation control? (24367255)
2013
16
Successful treatment of hepatitis B virus infection and related cryoglobulinaemic purpura with nucleoside/nucleotide analogues. (23190931)
2013
17
Hepatitis B virus infection and fatty liver in the general population. (22027575)
2012
18
Multiple outbreaks of hepatitis B virus infection related to assisted monitoring of blood glucose among residents of assisted living facilities--Virginia, 2009-2011. (22592272)
2012
19
Prevalence of hepatitis B virus infection in a highly endemic area of southern China after catch-up immunization. (22499009)
2012
20
The association of hepatitis B virus infection with B-cell non-Hodgkin lymphoma - a review. (22432084)
2012
21
IL28B rs12979860 polymorphism does not influence outcomes of hepatitis B virus infection. (22239156)
2012
22
Occult hepatitis B virus infection in hemodialysis patients in Recife, State of Pernambuco, Brazil. (23152336)
2012
23
The correlation between hepatitis B virus infection and IL-27. (22766719)
2012
24
Predictive value of alpha-fetoprotein in the long-term risk of developing hepatocellular carcinoma in patients with hepatitis B virus infection--results from a clinic-based longitudinal cohort. (22436980)
2012
25
Adenovirus-expressed preS2 antibody inhibits hepatitis B virus infection and hepatic carcinogenesis. (22294841)
2012
26
Multiple cerebral arterial stenosis associated with hepatitis B virus infection. (21519526)
2011
27
Natural history of hepatitis B virus infection: pediatric perspective. (20812021)
2011
28
Hepatitis C and hepatitis B virus infection: epidemiology and risk factors in a large cohort of pregnant women in Lorestan, West of Iran. (22235217)
2011
29
Countering hepatitis B virus infection using RNAi: how far are we from the clinic? (21913277)
2011
30
Role of the coinhibitory receptor cytotoxic T lymphocyte antigen-4 on apoptosis-Prone CD8 T cells in persistent hepatitis B virus infection. (21360567)
2011
31
Iranian dental students' knowledge of hepatitis B virus infection and its control practices. (22184603)
2011
32
Occult hepatitis B virus infection: bit player or role player? (21735471)
2011
33
Genetic analysis of complement component 9 (C9) polymorphisms with clearance of hepatitis B virus infection. (21380615)
2011
34
Future aspects of therapy for hepatitis B virus infection: value of surrogate markers, innovative therapy, and global collaboration. (21526371)
2011
35
Correlation between gastrointestinal fungi and varying degrees of chronic hepatitis B virus infection. (20846815)
2011
36
An overview of occult hepatitis B virus infection. (21528070)
2011
37
Associations between cytotoxic T lymphocyte-associated antigen-4 polymorphisms and serum tumor necrosis factor-I+ and interferon-I^ levels in patients with chronic hepatitis B virus infection. (21847627)
2011
38
Occult hepatitis B virus infection: a complex entity with relevant clinical implications. (21472115)
2011
39
The diagnostic value of ultrasound elastography in patients with hepatitis B virus infection: a prospective study. (21227017)
2010
40
Association of polymorphisms of programmed cell death-1 gene with chronic hepatitis B virus infection. (20837075)
2010
41
Role of serum prothrombin induced by vitamin K absence or antagonist-II in the early detection of hepatocellular carcinoma in patients with chronic hepatitis B virus infection. (19391065)
2009
42
CD24 polymorphisms affect risk and progression of chronic hepatitis B virus infection. (19610054)
2009
43
Programmed death-1 expression is associated with the disease status in hepatitis B virus infection. (18680238)
2008
44
Effects of GSTT1, GSTM1 and GSTP1 gene polymorphism on the course of hepatitis B virus infection. (19102379)
2008
45
Cytokine gene polymorphisms in Japanese patients with hepatitis B virus infection--association between TGF-beta1 polymorphisms and hepatocellular carcinoma. (15763337)
2005
46
RANTES gene single nucleotide polymorphisms and expression in patients with chronic hepatitis B virus infection. (15978191)
2005
47
Markers of disease activity in chronic hepatitis B virus infection. (12659467)
2003
48
Heterozygote advantage for HLA class-II type in hepatitis B virus infection. (9288086)
1997
49
Exacerbation of peripheral neuropathy during alpha-interferon therapy in a patient with mixed cryoglobulinemia and hepatitis B virus infection. (8877939)
1996
50
Expression of leukocyte adhesion molecules in the liver of patients with chronic hepatitis B virus infection. (1704328)
1991

Variations for Hepatitis B Virus Infection

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Clinvar genetic disease variations for Hepatitis B Virus Infection:

6
id Gene Name Type Significance SNP ID Assembly Location
1IL10RBNM_000628.4(IL10RB): c.139A> G (p.Lys47Glu)single nucleotide variantrisk factorrs2834167GRCh37Chr 21, 34640788: 34640788
2IFNAR2NM_207585.2(IFNAR2): c.23T> C (p.Phe8Ser)single nucleotide variantrisk factorrs2229207GRCh37Chr 21, 34614250: 34614250

Expression for genes affiliated with Hepatitis B Virus Infection

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Expression patterns in normal tissues for genes affiliated with Hepatitis B Virus Infection

Search GEO for disease gene expression data for Hepatitis B Virus Infection.

Pathways for genes affiliated with Hepatitis B Virus Infection

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Compounds for genes affiliated with Hepatitis B Virus Infection

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Compounds related to Hepatitis B Virus Infection according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1peginterferon alfa-2b50 1111.1IFNAR2, IFNL3
2peginterferon alfa-2a50 1110.8IFNAR2, IFNL3

GO Terms for genes affiliated with Hepatitis B Virus Infection

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Biological processes related to Hepatitis B Virus Infection according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of transpositionGO:01052910.1APOBEC3B, APOBEC3A
2defense response to virusGO:0516079.8IFNL3, APOBEC3B, APOBEC3A
3cytokine-mediated signaling pathwayGO:0192219.7IL10RB, IFNAR2, IFNGR1
4innate immune responseGO:0450879.3KIR2DS2, KIR2DS1, APOBEC3B, APOBEC3A
5signal transductionGO:0071659.1IFNGR1, IL10RB, PDCD1, KIR2DS1, KIR2DS2

Molecular functions related to Hepatitis B Virus Infection according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1deoxycytidine deaminase activityGO:04784410.0APOBEC3B, APOBEC3A

Products for genes affiliated with Hepatitis B Virus Infection

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  • Antibodies
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Sources for Hepatitis B Virus Infection

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet