MCID: HPT007
MIFTS: 57

Hepatitis E

Categories: Rare diseases, Infectious diseases, Liver diseases, Gastrointestinal diseases, Immune diseases, Genetic diseases

Aliases & Classifications for Hepatitis E

MalaCards integrated aliases for Hepatitis E:

Name: Hepatitis E 12 72 49 51 41 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:4411
MeSH 41 D016751
SNOMED-CT 64 7111000119109
UMLS 69 C0085293

Summaries for Hepatitis E

Disease Ontology : 12 A viral infectious disease that results_in inflammation located in liver, has material basis in Hepatitis E virus, which is transmitted_by ingestion of contaminated food. The infection has symptom fever, has symptom fatigue, has symptom loss of appetite, has symptom nausea, has symptom vomiting, has symptom abdominal pain, has symptom clay-colored bowel movements, has symptom dark urine, has symptom joint pain, and has symptom jaundice.

MalaCards based summary : Hepatitis E is related to hepatitis and acute liver failure, and has symptoms including fever, fatigue and loss of appetite. An important gene associated with Hepatitis E is CD40LG (CD40 Ligand), and among its related pathways/superpathways are Influenza A and RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways. The drugs Aluminum hydroxide and Aluminum sulfate have been mentioned in the context of this disorder. Affiliated tissues include liver, liver and kidney, and related phenotypes are cardiovascular system and digestive/alimentary

Wikipedia : 72 Hepatitis E is a viral hepatitis (liver inflammation) caused by infection with a virus called hepatitis... more...

Related Diseases for Hepatitis E

Diseases in the Hepatitis family:

Hepatitis C Virus Autoimmune Hepatitis
Hepatitis B Hepatitis a
Hepatitis C Viral Hepatitis
Hepatitis D Hepatitis E

Diseases related to Hepatitis E via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 210)
# Related Disease Score Top Affiliating Genes
1 hepatitis 31.5 DDX58 F2 GPT TNF
2 acute liver failure 30.4 ALB F2 GPT
3 hepatitis a 30.3 ALB F2 GPT TNF
4 guillain-barre syndrome 30.1 ALB CD40LG TNF
5 viral hepatitis 29.9 ALB CD40LG F2 GPT TNF
6 autoimmune hepatitis 29.9 CD40LG F2 GPT
7 cholecystitis 29.7 ALB F2 GPT
8 bilirubin metabolic disorder 29.7 ALB F2 GPT
9 liver disease 29.7 ALB F2 GPT TNF
10 hepatitis d 29.7 CD40LG F2 GPT
11 alcoholic hepatitis 29.6 ALB F2 GPT TNF
12 leptospirosis 29.6 CD40LG F2 TNF
13 hepatitis b 29.2 ALB F2 GPT IFNG TLR3 TNF
14 hepatitis c 29.1 DDX58 GPT IFNG TLR3 TNF
15 antipyrine metabolism 10.5 ALB F2
16 non-a-e hepatitis 10.5 ALB F2
17 hepatoportal sclerosis 10.5 F2 GPT
18 staphylococcal toxic shock syndrome 10.5 IFNG TNF
19 autoimmune myocarditis 10.4 IFNG TNF
20 colorado tick fever 10.4 ALB CD40LG
21 marburg hemorrhagic fever 10.4 F2 TNF
22 cork-handlers' disease 10.4 ALB CD40LG
23 abdominal tuberculosis 10.4 ALB F2
24 chronic beryllium disease 10.4 IFNG TNF
25 trichosporonosis 10.4 IFNG TNF
26 adult dermatomyositis 10.4 GPT TNF
27 plasmodium malariae malaria 10.4 ALB CD40LG
28 livedoid vasculopathy 10.4 CD40LG F2
29 african tick-bite fever 10.4 CD40LG IFNG
30 cat-scratch disease 10.4 CD40LG IFNG
31 fascioliasis 10.4 ALB GPT IFNG
32 kwashiorkor 10.4 ALB F2 GPT
33 hepatic tuberculosis 10.4 ALB F2 GPT
34 hepatic coma 10.4 ALB F2 GPT
35 chronic graft versus host disease 10.4 ALB IFNG
36 variola major 10.4 IFNG TLR3
37 trench fever 10.4 CD40LG TNF
38 encephalitozoonosis 10.4 CD40LG TNF
39 burns 10.4 ALB TNF
40 choledocholithiasis 10.4 ALB F2 GPT
41 rheumatoid lung disease 10.4 CD40LG TNF
42 sporotrichosis 10.4 CD40LG IFNG
43 analbuminemia 10.4 ALB F2 GPT
44 hypersplenism 10.3 ALB F2 IFNG
45 salmonellosis 10.3 ALB GPT IFNG
46 bile duct disease 10.3 ALB F2 GPT
47 nonalcoholic steatohepatitis 10.3 F2 GPT TNF
48 miller fisher syndrome 10.3 CD40LG TNF
49 spotted fever 10.3 F2 IFNG TNF
50 clonorchiasis 10.3 IFNG TNF

Graphical network of the top 20 diseases related to Hepatitis E:



Diseases related to Hepatitis E

Symptoms & Phenotypes for Hepatitis E

Symptoms:

12
  • fever
  • fatigue
  • loss of appetite
  • nausea
  • vomiting
  • abdominal pain
  • clay-colored bowel movements
  • dark urine
  • joint pain
  • jaundice

MGI Mouse Phenotypes related to Hepatitis E:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.06 TLR3 EP300 F2 ATF4 FGB CD40LG
2 digestive/alimentary MP:0005381 10.03 DDX58 EP300 ALB F2 ATF4 IFNG
3 hematopoietic system MP:0005397 10.02 DDX58 TLR3 EP300 F2 ATF4 CD40LG
4 homeostasis/metabolism MP:0005376 10.02 DDX58 TLR3 EP300 ALB F2 ATF4
5 endocrine/exocrine gland MP:0005379 10.01 TLR3 EP300 ALB ATF4 FGB CD40LG
6 mortality/aging MP:0010768 9.96 DDX58 EP300 ALB F2 ATF4 CD40LG
7 muscle MP:0005369 9.63 IFNG EP300 ALB ATF4 TLR3 TNF
8 neoplasm MP:0002006 9.43 DDX58 TLR3 EP300 ALB IFNG TNF
9 reproductive system MP:0005389 9.17 IFNG F2 ATF4 FGB CD40LG TLR3

Drugs & Therapeutics for Hepatitis E

Drugs for Hepatitis E (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 34)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aluminum hydroxide Approved, Investigational Phase 4,Phase 3 21645-51-2
2
Aluminum sulfate Approved Phase 4,Phase 3 10043-01-3
3
Ribavirin Approved Phase 4,Phase 2 36791-04-5 37542
4 Vaccines Phase 4,Phase 3,Phase 2,Phase 1
5 Anti-Infective Agents Phase 4,Phase 2
6 Antiviral Agents Phase 4,Phase 2
7 Antimetabolites Phase 4,Phase 2
8
Niacin Approved, Investigational, Nutraceutical Phase 2, Phase 3 59-67-6 938
9
Riboflavin Approved, Investigational, Nutraceutical, Vet_approved Phase 2, Phase 3 83-88-5 493570
10
Nicotinamide Approved, Investigational, Nutraceutical Phase 2, Phase 3 98-92-0 936
11
Thiamine Approved, Investigational, Nutraceutical, Vet_approved Phase 2, Phase 3 59-43-8 1130
12
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2, Phase 3 59-30-3 6037
13 Micronutrients Phase 2, Phase 3
14 Trace Elements Phase 2, Phase 3
15 Nicotinic Acids Phase 2, Phase 3
16 Vitamin B Complex Phase 2, Phase 3
17 Vitamins Phase 2, Phase 3
18 Protective Agents Phase 2, Phase 3
19 Antioxidants Phase 2, Phase 3
20 silymarin Nutraceutical Phase 2, Phase 3
21 Folate Nutraceutical Phase 2, Phase 3
22 Milk Thistle Nutraceutical Phase 2, Phase 3
23 Vitamin B2 Nutraceutical Phase 2, Phase 3
24 Vitamin B3 Nutraceutical Phase 2, Phase 3
25 Vitamin B9 Nutraceutical Phase 2, Phase 3
26 Thiamin Nutraceutical Phase 2, Phase 3
27
Entecavir Approved, Investigational Phase 2 142217-69-4 153941
28
Peginterferon alfa-2a Approved, Investigational Phase 2 198153-51-4 5360545
29
Sofosbuvir Approved Phase 2 1190307-88-0 45375808
30 interferons Phase 2
31 Liver Extracts Phase 2
32
Permethrin Approved, Investigational 52645-53-1 40326
33 Immunoglobulins
34 Antibodies

Interventional clinical trials:

(show all 28)

# Name Status NCT ID Phase Drugs
1 Phase Ⅳ Clinical Trial of Recombinant Hepatitis E Vaccine(Hecolin®) Unknown status NCT02189603 Phase 4
2 A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Chronic Hepatitis B Patients ) Completed NCT02964910 Phase 4
3 A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli) Completed NCT02417597 Phase 4
4 A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(Coadministration With Recombinant Hepatitis B Vaccine) Completed NCT02584543 Phase 4
5 Effectiveness Trial to Evaluate Protection of Pregnant Women by Hepatitis E Vaccine in Bangladesh. Recruiting NCT02759991 Phase 4 Hecolin;Hepa-B
6 A Study on the Recombinant Hepatitis E Vaccine (Escherichia Coli) (Accelerated Vaccination Schedule) Active, not recruiting NCT03168412 Phase 4
7 Ribavirin for Severe Acute and Chronic Hepatitis E Virus Infection. Active, not recruiting NCT02558114 Phase 4 Ribavirin
8 A Phase Ⅳ Clinical Trial of the Recombinant Hepatitis E Vaccine (Escherichia Coli)(the Lot Consistency Trial) Withdrawn NCT03365921 Phase 4
9 Clinical Trial of Recombinant Hepatitis E Vaccine Unknown status NCT01014845 Phase 3
10 Efficacy and Immunogenicity Study of Recombinant Human Papillomavirus Bivalent(Type 16/18 )Vaccine Active, not recruiting NCT01735006 Phase 3
11 Field Trial of Maternal Influenza Immunization in Asia Active, not recruiting NCT01034254 Phase 3
12 Randomized Placebo-controlled Trial Evaluating the Safety and Efficacy of Silymarin Treatment in Patients With Acute Viral Hepatitis Terminated NCT00755950 Phase 2, Phase 3
13 Immunogenicity Study of the Recombinant Human Papillomavirus Virus Type 6/11 Bivalent Vaccine Unknown status NCT02710851 Phase 2
14 Dose Ranging Study of Pegylated Interferon Lambda in Patients With Hepatitis B and Positive for the Hepatitis B e Antigen Completed NCT01204762 Phase 2 pegIFN;pegIFNα-2a;PegIFN lambda;Entecavir
15 HepNet Pilot Trial: Multicenter Trial for the Treatment of Chronic Hepatitis E With Sofosbuvir (SofE) Recruiting NCT03282474 Phase 2 Sofosbuvir
16 A Trial of Ribavirin in Patients With ACLF Due to Hepatitis E Virus Recruiting NCT01698723 Phase 2 Ribavirin;Placebo
17 A Safety and Efficacy Study of the Hepatitis E Vaccine in Nepal. Withdrawn NCT00287469 Phase 2
18 A Clinical Trial to Evaluate a Recombinant Hepatitis E Vaccine in Healthy Adults Completed NCT02603055 Phase 1
19 Epidemiological Study of Hepatitis E Virus in Maintenance Hemodialysis Patients Unknown status NCT02645955
20 Role of Cytokines in Hepatitis E Virus Infection During Pregnancy Completed NCT01062321
21 Host Responses in Kidney-transplant Recipients With Chronic Hepatitis E Virus Infection Completed NCT01090232
22 Prevalence of Antibodies to Selected Porcine Viruses in Patients With Cystic Fibrosis Receiving Porcine-derived Pancreatic Enzyme Replacement Therapy Completed NCT01858519
23 Study of the Immunogenicity and Efficacy of HBsAg Vaccine in Combination With Standard Antiviral Therapy With HB110E Completed NCT01813487 HBsAg vaccine with Entecavir
24 Seroprevalence of Hepatitis E in HIV Positive Patients in Basque Country in 2016 (VIhVhEpb) Recruiting NCT02847507
25 Hepatitis E Virus Infection in Pediatric Transplantation, a Prevalence Study Recruiting NCT02809885
26 Seroprevalence of Hepatitis E in People With an Organ Transplant Recruiting NCT02190253
27 Investigation of Endemic and Emerging Diseases in Populations of Homeless Households in Marseille. Recruiting NCT02819128
28 The Epidemiology of Hepatitis E Virus Infection in Israel and Potential Risk Factors Enrolling by invitation NCT02419625

Search NIH Clinical Center for Hepatitis E

Cochrane evidence based reviews: hepatitis e

Genetic Tests for Hepatitis E

Anatomical Context for Hepatitis E

The Foundational Model of Anatomy Ontology organs/tissues related to Hepatitis E:

18
Liver

MalaCards organs/tissues related to Hepatitis E:

38
Liver, Kidney, Testes, T Cells, B Cells, Thyroid, Lung

Publications for Hepatitis E

Articles related to Hepatitis E:

(show top 50) (show all 764)
# Title Authors Year
1
Substitution of amino acid residue V1213 in the helicase domain of the genotype 3 hepatitis E virus reduces virus replication. ( 29422085 )
2018
2
Benign recurrent intrahepatic cholestasis (BRIC)-like episode associated with ATP8B1 variation underlying protracted cholestatic course of acute hepatitis E virus infection. ( 29191380 )
2018
3
Chronic Hepatitis E in a Renal Transplant Recipient: The First Report of Genotype 4 Hepatitis E Virus Caused Chronic InfectionA in Organ Recipient. ( 29432746 )
2018
4
Aujeszky's Disease and Hepatitis E Viruses Transmission between Domestic Pigs and Wild Boars in Corsica: Evaluating the Importance of Wild/Domestic Interactions and the Efficacy of Management Measures. ( 29417054 )
2018
5
The identification and characterization of novel rat hepatitis E virus strains in Bali and Sumbawa, Indonesia. ( 29404765 )
2018
6
Hepatitis E virus infection of slaughtered healthy pigs in Brazil. ( 29441690 )
2018
7
Host-Virus Protein Interaction Network Reveals the Involvement of Multiple Host Processes in the Life Cycle of Hepatitis E Virus. ( 29404423 )
2018
8
Comparison of hepatitis E virus seroprevalence between HBsAg-positive population and healthy controls in Shandong province, China. ( 29433428 )
2018
9
Guillain-Barre syndrome caused by hepatitis E infection: case report and literature review. ( 29357816 )
2018
10
Treating chronic hepatitis E: when is enough enough? ( 29391359 )
2018
11
Proposal for a new subtype of the zoonotic genotype 3 Hepatitis E virus: HEV-3l. ( 29452164 )
2018
12
Origin and dispersal of Hepatitis E virus. ( 29410449 )
2018
13
Hepatitis E virus replication and interferon responses in human placental cells. ( 29404525 )
2018
14
Prevalence of hepatitis E virus RNA and antibodies in a cohort of kidney transplant recipients in Central Brazil. ( 29408465 )
2018
15
Elucidating the differences in pathogenicity between hepatitis E virus genotypes: The quest continues. ( 29404519 )
2018
16
Acute hepatitis E in India appears to be caused exclusively by genotype 1 hepatitis E virus. ( 29399748 )
2018
17
Hepatitis E outbreak at a nursing home for aged people in Hokkaido, Japan, between February and March 2016. ( 29414183 )
2018
18
Replication of hepatitis E virus in the ovary and promotion of oocyte apoptosis in rabbits infected with HEV-4. ( 29435117 )
2018
19
First Report of the Presence of Hepatitis E Virus in Scottish-Harvested Shellfish Purchased at Retail Level. ( 29442296 )
2018
20
Transfusion-Transmitted Hepatitis E: NAT Screening of Blood Donations and Infectious Dose. ( 29450199 )
2018
21
Course of hepatitis E infection in a patient with rheumatoid arthritis and autoimmune hepatitis: A case report. ( 29390558 )
2017
22
Hepatitis E virus detected from Chinese laboratory ferrets and farmed mink. ( 28941157 )
2017
23
Parsonage-Turner syndrome due to autochthonous acute genotype 3f hepatitis E virus infection in a nonimmunocompromised 55-year-old patient. ( 28439773 )
2017
24
Systematic review of mixed cryoglobulinemia associated with hepatitis E virus infection: association or causation? ( 28852522 )
2017
25
Brainstem encephalitis and acute polyneuropathy associated with hepatitis E infection. ( 28899886 )
2017
26
Systematic identification of hepatitis E virus ORF2 interactome reveals that TMEM134 engages in ORF2-mediated NF-I_B pathway. ( 27899274 )
2017
27
Prevalence of lapine rotavirus, astrovirus, and hepatitis E virus in Canadian domestic rabbit populations. ( 28888629 )
2017
28
A High clinical manifestation rate in an imported outbreak of hepatitis E genotype 1 infection in a German group of travellers returning from India. ( 28051793 )
2017
29
Hepatitis E virus seroprevalence among the general population in a livestock-dense area in the Netherlands: a cross-sectional population-based serological survey. ( 28056844 )
2017
30
Acute Non-Fulminant Viral Hepatitis E Presenting with Acute Pancreatitis-An Unusual Presentation. ( 28951695 )
2017
31
Seroprevalence of anti-hepatitis E virus antibodies in domestic pigs in Mexico. ( 28934965 )
2017
32
Fetomaternal outcomes in pregnant women with hepatitis E infection; still an important fetomaternal killer with an unresolved mystery of increased virulence in pregnancy. ( 28913146 )
2017
33
Prevalence of Antibodies Against Hepatitis E Virus in Veterinarians in Estonia. ( 28933680 )
2017
34
Investigation of underlying comorbidities as risk factors for symptomatic human hepatitis E virus infection. ( 28078736 )
2017
35
Effect of housing arrangement on fecal-oral transmission of avian hepatitis E virus in chicken flocks. ( 28882185 )
2017
36
Hepatitis E. ( 28910479 )
2017
37
Fulminant hepatitis E in an infant. ( 29417024 )
2017
38
Detection of rat hepatitis E virus in wild Norway rats (Rattus norvegicus) and Black rats (Rattus rattus) from 11 European countries. ( 28888650 )
2017
39
High frequency of hepatitis E virus infection in swine from South Brazil and close similarity to human HEV isolates. ( 28089613 )
2017
40
Hepatitis E Virus-Associated Meningoencephalitis in a Lung Transplant Recipient Diagnosed by Clinical Metagenomic Sequencing. ( 28721353 )
2017
41
Acute kidney injury, a rare complication of acute hepatitis E infection. ( 28943169 )
2017
42
RIG-I is a key antiviral interferon-stimulated gene against hepatitis E virus regardless of interferon production. ( 28195391 )
2017
43
Familial Hepatitis E Outbreak Linked to Wild Boar Meat Consumption. ( 28067990 )
2017
44
Using data linkage to improve surveillance methods for acute hepatitis E infections in England and Wales 2010-2016. ( 28946932 )
2017
45
Biological or pharmacological activation of protein kinase C alpha constrains hepatitis E virus replication. ( 28077314 )
2017
46
Epidemiology of hepatitis E infection in Hong Kong. ( 28943523 )
2017
47
Chronic hepatitis E virus infection in a cirrhotic patient: A case report. ( 28953614 )
2017
48
Hepatitis E in transfusion-dependent thalassaemia patients, in Greece: a single centre experience. ( 28891120 )
2017
49
Fatal autochthonous fulminant hepatitis E early after allogeneic stem cell transplantation. ( 28067868 )
2017
50
Capturing virus evolution by proteomic bioinformatics: Hunting for characteristic mutations in the hepatitis E virus genome. ( 28945510 )
2017

Variations for Hepatitis E

Expression for Hepatitis E

Search GEO for disease gene expression data for Hepatitis E.

Pathways for Hepatitis E

Pathways related to Hepatitis E according to GeneCards Suite gene sharing:

(show all 20)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.55 DDX58 EP300 IFNG TLR3 TNF
2
Show member pathways
12.52 DDX58 EP300 IFNG TNF
3
Show member pathways
12.49 CD40LG EP300 TLR3 TNF
4
Show member pathways
12.46 ATF4 CD40LG IFNG TNF
5
Show member pathways
12.42 ATF4 CD40LG TLR3 TNF
6
Show member pathways
12.11 ALB F2 IFNG TNF
7
Show member pathways
12.07 ATF4 DDX58 EP300 TLR3 TNF
8 11.87 CD40LG DDX58 IFNG TLR3 TNF
9 11.86 DDX58 TLR3 TNF
10
Show member pathways
11.8 IFNG TLR3 TNF VPS4A
11
Show member pathways
11.74 IFNG TLR3 TNF
12 11.69 CD40LG DDX58 TNF
13 11.62 EP300 IFNG TNF
14
Show member pathways
11.57 CD40LG IFNG TNF
15
Show member pathways
11.47 CD40LG IFNG TNF
16 11.37 EP300 IFNG TNF
17
Show member pathways
11.32 ATF4 EP300 IFNG TLR3 TNF
18
Show member pathways
11.28 EP300 IFNG TNF
19 11.23 CD40LG IFNG TNF
20 11.18 EP300 IFNG TNF

GO Terms for Hepatitis E

Cellular components related to Hepatitis E according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.5 ALB CD40LG F2 FGB GPT IFNG
2 external side of plasma membrane GO:0009897 8.92 CD40LG F2 FGB TNF

Biological processes related to Hepatitis E according to GeneCards Suite gene sharing:

(show all 25)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.77 CD40LG TLR3 TNF
2 platelet activation GO:0030168 9.74 CD40LG F2 FGB
3 positive regulation of DNA binding transcription factor activity GO:0051091 9.72 DDX58 EP300 TNF
4 positive regulation of protein phosphorylation GO:0001934 9.71 F2 IFNG TLR3 TNF
5 positive regulation of interleukin-6 production GO:0032755 9.63 DDX58 TLR3 TNF
6 positive regulation of protein complex assembly GO:0031334 9.62 IFNG TNF
7 positive regulation of NF-kappaB import into nucleus GO:0042346 9.62 TLR3 TNF
8 fibrinolysis GO:0042730 9.61 F2 FGB
9 positive regulation of osteoclast differentiation GO:0045672 9.61 IFNG TNF
10 extrinsic apoptotic signaling pathway GO:0097191 9.61 IFNG TLR3 TNF
11 positive regulation of chemokine production GO:0032722 9.59 TLR3 TNF
12 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.58 IFNG TNF
13 cellular response to exogenous dsRNA GO:0071360 9.58 DDX58 TLR3
14 positive regulation of exosomal secretion GO:1903543 9.56 IFNG VPS4A
15 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.54 FGB TNF
16 positive regulation of chemokine biosynthetic process GO:0045080 9.52 TLR3 TNF
17 necroptotic signaling pathway GO:0097527 9.51 TLR3 TNF
18 detection of virus GO:0009597 9.49 DDX58 TLR3
19 regulation of immunoglobulin secretion GO:0051023 9.48 CD40LG TNF
20 positive regulation of interleukin-8 production GO:0032757 9.43 DDX58 TLR3 TNF
21 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.37 IFNG TNF
22 positive regulation of interleukin-12 production GO:0032735 9.33 CD40LG IFNG TLR3
23 positive regulation of vitamin D biosynthetic process GO:0060557 9.32 IFNG TNF
24 response to virus GO:0009615 9.26 DDX58 IFNG TLR3 TNF
25 positive regulation of gene expression GO:0010628 9.1 ATF4 DDX58 EP300 IFNG TLR3 TNF

Sources for Hepatitis E

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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