HBL
MCID: HPT022
MIFTS: 43

Hepatoblastoma (HBL) malady

Rare diseases, Liver diseases, Cancer diseases categories

Summaries for Hepatoblastoma

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Wikipedia:64 Hepatoblastoma is an uncommon malignant liver neoplasm occurring in infants and children and composed of... more...

MalaCards based summary: Hepatoblastoma, also known as HBL, is related to hepatitis and hepatocellular carcinoma. An important gene associated with Hepatoblastoma is APC (adenomatous polyposis coli). Affiliated tissues include liver, fetal liver and lung.

Aliases & Classifications for Hepatoblastoma

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Sources:
9Disease Ontology, 42NIH Rare Diseases, 23GTR, 11DISEASES, 44Novoseek, 48Orphanet, 61UMLS, 34MeSH, 56SNOMED-CT, 39NCIt, 35MESH via Orphanet, 27ICD10 via Orphanet, 62UMLS via Orphanet
See all sources

Hepatoblastoma, Aliases & Descriptions:

Name: Hepatoblastoma 9 42 23 11 44 48 61
 
Hbl 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Anatomical: Liver diseases


Characteristics (Orphanet epidemiological data):

48
hepatoblastoma:
Inheritance: Sporadic; Age of onset: Childhood


External Ids:

Disease Ontology9 DOID:687
MeSH34 D018197
NCIt39 C3728
SNOMED-CT56 109843000, 45024009
MESH via Orphanet35 D018197
ICD10 via Orphanet27 C22.2
UMLS via Orphanet62 C0206624

Related Diseases for Hepatoblastoma

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Graphical network of the top 20 diseases related to Hepatoblastoma:



Diseases related to hepatoblastoma

Symptoms for Hepatoblastoma

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Drugs & Therapeutics for Hepatoblastoma

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Drug clinical trials:

Search ClinicalTrials for Hepatoblastoma

Search NIH Clinical Center for Hepatoblastoma

Genetic Tests for Hepatoblastoma

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Genetic tests related to Hepatoblastoma:

id Genetic test Affiliating Genes
1 Hepatoblastoma23

Anatomical Context for Hepatoblastoma

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MalaCards organs/tissues related to Hepatoblastoma:

32
Liver, Fetal liver, Lung, Brain, Kidney, Heart, Thyroid, Breast, Prostate, Nk cells, Endothelial

Animal Models for Hepatoblastoma or affiliated genes

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Publications for Hepatoblastoma

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Articles related to Hepatoblastoma:

(show top 50)    (show all 684)
idTitleAuthorsYear
1
Neonatal medical exposures and characteristics of low birth weight hepatoblastoma cases: a report from the Children's Oncology Group. (25044669)
2014
2
Unravelling the genetics of hepatoblastoma: Few mutations, what else? (25239079)
2014
3
Hepatoblastoma evaluated by 18F-fluoromethyl choline PET/CT. (23334143)
2013
4
Analysis of national and single-center incidence and survival after liver transplantation for hepatoblastoma: new trends and future opportunities. (23331862)
2013
5
Epigallocatechin-3-gallate inhibits hepatoblastoma growth by reactivating the Wnt inhibitor SFRP1. (24127655)
2013
6
Imaging analysis of hepatoblastoma resectability across neoadjuvant chemotherapy. (23845613)
2013
7
High mobility group AT-hook 2 is overexpressed in hepatoblastoma. (23134771)
2013
8
ER stress and ASK1-JNK activation contribute to oridonin-induced apoptosis and growth inhibition in cultured human hepatoblastoma HuH-6 cells. (23580093)
2013
9
Cytogenetics of hepatoblastoma. (22201954)
2012
10
Hepatoblastoma in an infant with paternal uniparental disomy 14. (23181499)
2012
11
A fetus with a huge neck mass and a large abdominal circumference--a rare case of sialoblastoma and hepatoblastoma. (22711473)
2012
12
Prognostic implications of serum alpha-fetoprotein response during treatment of hepatoblastoma. (21370433)
2011
13
Initial liver transplantation for unresectable hepatoblastoma after chemotherapy. (21910210)
2011
14
Hepatoblastoma with tumor extension through the inferior vena cava into the right atrium. (20479678)
2010
15
Sterol-regulatory-element-binding protein 2 and nuclear factor Y control human farnesyl diphosphate synthase expression and affect cell proliferation in hepatoblastoma cells. (20450493)
2010
16
Hepatoblastoma in association with bilateral polycystic kidneys. (21034924)
2010
17
Altered microRNA Expression Patterns in Hepatoblastoma Patients. (19701500)
2009
18
Overexpression of Dickkopf 3 in hepatoblastomas and hepatocellular carcinomas. (19437037)
2009
19
Arachidonic Acid Activates K-Cl-cotransport in HepG2 Human Hepatoblastoma Cells. (19915704)
2009
20
Treatment-related acute myelomonocytic leukemia with t(11;19) in a child following chemotherapy for hepatoblastoma. (17973320)
2008
21
Hepatoblastoma in a Noonan syndrome patient with a PTPN11 mutation. (18253957)
2008
22
In vitro and in vivo evaluation of photodynamic techniques for the experimental treatment of human hepatoblastoma and neuroblastoma: preliminary results. (19009300)
2008
23
Evaluation and treatment of hepatoblastoma. (16423617)
2006
24
Hepatoblastoma: why so many low-birth-weight infants? (16456653)
2006
25
Chromosome 7 aberrations in a young girl with myelodysplasia and hepatoblastoma: an unusual association. (16317299)
2006
26
Second case of hepatoblastoma in a young patient with Simpson-Golabi-Behmel syndrome. (16166055)
2005
27
Liver transplantation for hepatoblastoma: results from the International Society of Pediatric Oncology (SIOP) study SIOPEL-1 and review of the world experience. (14752798)
2004
28
Curative resection by superior hepatectomy for advanced hepatoblastoma facilitated by the presence of a large inferior right hepatic vein. (18333062)
2004
29
Brain metastases in hepatoblastoma. (15087112)
2004
30
Tamoxifen cytotoxicity in hepatoblastoma cells stably transfected with human CYP3A4. (15006542)
2004
31
Expression profiling and differential screening between hepatoblastomas and the corresponding normal livers: identification of high expression of the PLK1 oncogene as a poor-prognostic indicator of hepatoblastomas. (15221005)
2004
32
Improved survival outcome for hepatoblastoma based on an optimal chemotherapeutic regimen--a report from the study group for pediatric solid malignant tumors in the Kyushu area. (14966739)
2004
33
Hepatoblastoma in a girl with biliary atresia: coincidence or co-incidence. (15382280)
2004
34
Analysis of treatment outcome for children with recurrent or metastatic hepatoblastoma. (12768314)
2003
35
Serum alpha-fetoprotein screening for hepatoblastoma in children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia. (12970646)
2003
36
Orthotopic liver transplantation for unresectable hepatoblastoma. (12352881)
2002
37
Hepatoblastoma: assessment of criteria for histologic classification. (12228903)
2002
38
Beta-catenin mutations and protein accumulation in all hepatoblastomas examined from B6C3F1 mice treated with anthraquinone or oxazepam. (10850429)
2000
39
Role of Ca2+ influx in the tert-butyl hydroperoxide-induced apoptosis of HepG2 human hepatoblastoma cells. (9873835)
1998
40
Thrombopoietin in patients with hepatoblastoma. (9766812)
1998
41
Hepatoblastoma and APC gene mutation in familial adenomatous polyposis. (9378405)
1997
42
Timing and magnitude of decline in alpha-fetoprotein levels in treated children with unresectable or metastatic hepatoblastoma are predictors of outcome: a report from the Children's Cancer Group. (9060563)
1997
43
Hepatoblastoma and APC gene mutation in familial adenomatous polyposis. (9038672)
1996
44
Differential effects of insulin and insulin-like growth factor I on the production of plasma steroid-binding globulins by human hepatoblastoma-derived (Hep G2) cells. (7536204)
1995
45
Establishment and characterization of a novel hepatoblastoma-derived cell line. (7595832)
1995
46
Identification of a human immunodeficiency virus type 1 TAR binding protein in human hepatoblastoma HepG2 cells that trans-activates HIV-1 LTR-directed gene expression. (8286041)
1994
47
Production of interleukin-1 beta and interleukin-6 in hepatoblastoma. (8383628)
1993
48
Combined cystic teratoma and hepatoblastoma of the liver. Probable divergent differentiation of an uncommitted hepatic precursor cell. (8221556)
1993
49
Epithelial and mixed hepatoblastoma in the adult. Histological observations and general considerations. (1317555)
1992
50
Hepatoblastoma, pigmented ocular fundus lesions and jaw lesions in Gardner syndrome. (3354603)
1988

Variations for Hepatoblastoma

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Expression for genes affiliated with Hepatoblastoma

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Expression patterns in normal tissues for genes affiliated with Hepatoblastoma

Search GEO for disease gene expression data for Hepatoblastoma.

Pathways for genes affiliated with Hepatoblastoma

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Compounds for genes affiliated with Hepatoblastoma

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GO Terms for genes affiliated with Hepatoblastoma

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Products for genes affiliated with Hepatoblastoma

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Sources for Hepatoblastoma

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
29IUPHAR
30KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet