MCID: HPT066
MIFTS: 23

Hepatoportal Sclerosis malady

Liver diseases category

Summaries for Hepatoportal Sclerosis

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Sources:
32MalaCards
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MalaCards: Hepatoportal Sclerosis, also known as obliterative portal venopathy, is related to hypertension and portal hypertension. An important gene associated with Hepatoportal Sclerosis is ELN (elastin). The compounds ang ii and losartan have been mentioned in the context of this disorder. Affiliated tissues include liver.

Aliases & Classifications for Hepatoportal Sclerosis

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Sources:
48Orphanet, 26ICD10 via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Liver diseases


Characteristics (Orphanet epidemiological data):

48
obliterative portal venopathy:
Age of onset: Variable


Aliases & Descriptions:

hepatoportal sclerosis 48
obliterative portal venopathy 48


External Ids:

ICD10 via Orphanet26 K74.1

Related Diseases for Hepatoportal Sclerosis

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Hepatoportal Sclerosis:



Diseases related to hepatoportal sclerosis

Clinical Features for Hepatoportal Sclerosis

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Drugs & Therapeutics for Hepatoportal Sclerosis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Hepatoportal Sclerosis

Drug clinical trials:

Search ClinicalTrials for Hepatoportal Sclerosis

Search NIH Clinical Center for Hepatoportal Sclerosis

Search CenterWatch for Hepatoportal Sclerosis

Genetic Tests for Hepatoportal Sclerosis

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Anatomical Context for Hepatoportal Sclerosis

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Sources:
32MalaCards
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MalaCards organs/tissues related to Hepatoportal Sclerosis:

32
Liver

Animal Models for Hepatoportal Sclerosis or affiliated genes

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Publications for Hepatoportal Sclerosis

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Genetic Variations for Hepatoportal Sclerosis

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Expression for genes affiliated with Hepatoportal Sclerosis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hepatoportal Sclerosis

Search GEO for disease gene expression data for Hepatoportal Sclerosis.

Pathways for genes affiliated with Hepatoportal Sclerosis

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Compounds for genes affiliated with Hepatoportal Sclerosis

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Sources:
44Novoseek, 49PharmGKB, 28IUPHAR, 11DrugBank, 24HMDB, 59Tocris Bioscience
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Compounds related to Hepatoportal Sclerosis according to GeneCards/GeneDecks:

(show all 16)
idCompoundScoreTop Affiliating Genes
1ang ii449.6ACE, ELN
2losartan44 49 28 1112.5ACE, ELN
3diltiazem44 28 1111.4ACE, F2
4amiodarone44 49 28 1112.4ACE, F2
5clopidogrel49 44 11 2412.4F2, ACE
6nifedipine44 49 28 1112.4ELN, ACE
7digoxin44 49 59 11 2413.4ACE, F2
8kininogen449.3F2, ACE
9dermatan sulfate449.3F2, ELN
10polyethylene glycol449.2F2, ELN
11suramin44 28 1111.1ELN, F2
12hyaluronic acid44 2410.0F2, ELN
13n acetylcysteine449.0F2, ELN
14phosphatidylcholine448.9ELN, F2
15aspirin44 49 28 2411.8F2, ACE
16creatinine448.8ELN, F2, ACE

GO Terms for genes affiliated with Hepatoportal Sclerosis

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Sources:
16Gene Ontology
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Cellular components related to Hepatoportal Sclerosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055768.5ELN, ACE, F2

Biological processes related to Hepatoportal Sclerosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1blood vessel remodelingGO:0019749.3ELN, ACE

Products for genes affiliated with Hepatoportal Sclerosis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Hepatoportal Sclerosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet