MCID: HPT066
MIFTS: 21

Hepatoportal Sclerosis malady

Categories: Liver diseases, Rare diseases

Aliases & Classifications for Hepatoportal Sclerosis

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Sources:
52Orphanet, 29ICD10 via Orphanet
See all MalaCards sources

Aliases & Descriptions for Hepatoportal Sclerosis:

Name: Hepatoportal Sclerosis 52
 
Obliterative Portal Venopathy 52

Characteristics:

Orphanet epidemiological data:

52
obliterative portal venopathy:
Age of onset: All ages

Classifications:

Orphanet: 52 
Rare hepatic diseases


External Ids:

Orphanet52 ORPHA64743
ICD10 via Orphanet29 K74.1

Summaries for Hepatoportal Sclerosis

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MalaCards based summary: Hepatoportal Sclerosis, also known as obliterative portal venopathy, is related to portal hypertension and oliver syndrome. An important gene associated with Hepatoportal Sclerosis is ACE (Angiotensin I Converting Enzyme). Affiliated tissues include liver and endothelial.

Related Diseases for Hepatoportal Sclerosis

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Diseases related to Hepatoportal Sclerosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 42)
idRelated DiseaseScoreTop Affiliating Genes
1portal hypertension10.4
2oliver syndrome10.1
3adams-oliver syndrome10.1
4nodular regenerative hyperplasia10.1
5breast liposarcoma10.1ACE, ELN
6adams-oliver syndrome 510.0ACE, ELN
7ceroid lipofuscinosis, neuronal, 610.0ACE, ELN
8lung hilum cancer9.9ACE, ELN
9crohn's disease9.9
10myasthenia gravis9.9
11endotheliitis9.9
12duodenal disease9.9F2, GPT
13acute lymphocytic leukemia9.9F2, GPT
14alveolar periostitis9.9F2, GPT
15degenerative myopia9.9ACE, F2
16hepatocellular adenoma9.9ACE, F2
17bronchial disease9.9F2, GPT
18fibrous histiocytoma9.9F2, GPT
19joint disorders9.9ACE, F2
20ischemic heart disease9.9ACE, F2
21alpha-2-plasmin inhibitor deficiency9.9ACE, F2
22intraorbital meningioma9.9F2, GPT
23prostate malignant phyllodes tumor9.8ACE, F2
24hepatic coma9.8F2, GPT
25iron metabolism disease9.8ACE, ELN
26renal fibrosis9.8ACE, F2
27extrahepatic cholestasis9.8F2, GPT
28spinal canal and spinal cord meningioma9.8ACE, F2
29angina pectoris9.8ACE, F2
30eczematous dermatitis of eyelid9.8F2, GPT
31spinocerebellar ataxia 89.7F2, GPT
32frontal sinus cancer9.7ACE, F2
33common wart9.7ACE, F2
34adult respiratory distress syndrome9.7ACE, F2
35littre gland carcinoma9.6ACE, F2
36gemistocytic astrocytoma9.5ACE, F2
37peripheral artery disease9.5ACE, F2
38pyelonephritis9.4ACE, F2
39alcohol abuse9.3ACE, ELN, F2
40adrenal rest tumor9.3ACE, ELN, F2
41stroke, ischemic9.2ACE, F2
42paraneoplastic pemphigus8.8ACE, ELN, F2, GPT

Graphical network of the top 20 diseases related to Hepatoportal Sclerosis:



Diseases related to hepatoportal sclerosis

Symptoms for Hepatoportal Sclerosis

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Drugs & Therapeutics for Hepatoportal Sclerosis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Hepatoportal Sclerosis

Genetic Tests for Hepatoportal Sclerosis

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Anatomical Context for Hepatoportal Sclerosis

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MalaCards organs/tissues related to Hepatoportal Sclerosis:

34
Liver, Endothelial

Animal Models for Hepatoportal Sclerosis or affiliated genes

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Publications for Hepatoportal Sclerosis

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Articles related to Hepatoportal Sclerosis:

(show all 29)
idTitleAuthorsYear
1
Mercaptopurine-induced hepatoportal sclerosis in a patient with Crohn's disease. (22841133)
2013
2
Liver failure and the need for transplantation in 6 patients with hepatoportal sclerosis. (23769069)
2013
3
Hepatoportal sclerosis in childhood: descriptive analysis of 12 patients. (24133357)
2013
4
Hepatoportal sclerosis (obliterative portal venopathy) and nodular regenerative hyperplasia in a patient with myasthenia gravis: A case report and review of the published work. (23675894)
2013
5
Hepatoportal sclerosis clinical different evolutionary stages: presentation of 3 cases and literature review. (22372805)
2012
6
Induction of elastin expression in vascular endothelial cells relates to hepatoportal sclerosis in idiopathic portal hypertension: possible link to serum anti-endothelial cell antibodies. (22288597)
2012
7
Hepatoportal sclerosis: CT and MRI appearance with histopathologic correlation. (22268180)
2012
8
Oxaliplatin-induced hepatoportal sclerosis, portal hypertension, and variceal bleeding successfully treated with transjugular intrahepatic portosystemic shunt. (22537609)
2012
9
Hepatoportal sclerosis in childhood: some presenting with cholestatic features (a re-evaluation of 12 children). (22150463)
2012
10
The involvement of nitric oxide in the physiopathology of hepatoportal sclerosis. (22820432)
2012
11
Elevated levels of circulating angiotensin converting enzyme in patients with hepatoportal sclerosis. (21290180)
2011
12
Hepatoportal sclerosis and extrahepatic portal venous obstruction associated with anti-phospholipid antibody syndrome in child. (20675717)
2011
13
The development of hepatoportal sclerosis and portal hypertension due to didanosine use in HIV. (21057809)
2011
14
Variceal bleeding in an adolescent with HIV diagnosed with hepatoportal sclerosis and nodular regenerative hyperplasia. (19841596)
2010
15
Liver failure and the need for transplantation in three patients with hepatoportal sclerosis. (19100429)
2008
16
Response to Schiano et al. Hepatoportal sclerosis as a cause of noncirrhotic portal hypertension in patients with HIV. (18341510)
2008
17
Hepatoportal sclerosis: a cause of portal hypertension to bear in mind. (18279649)
2008
18
Clinical features, serum interleukin-6, and interferon-gamma levels of 34 turkish patients with hepatoportal sclerosis. (17404864)
2007
19
Hepatoportal sclerosis as a cause of noncirrhotic portal hypertension in patients with HIV. (17640321)
2007
20
Liver failure and need for liver transplantation in patients with advanced hepatoportal sclerosis. (17414109)
2007
21
Association of Adams-Oliver syndrome and hepatoportal sclerosis: an additional case. (16532468)
2006
22
Adams-Oliver syndrome and hepatoportal sclerosis: occasional association or common mechanism? (15832360)
2005
23
Hepatoportal sclerosis in a child. (15316776)
2004
24
Hepatoportal sclerosis. (8578318)
1995
25
Hepatoportal sclerosis demonstrated by abdominal ultrasonography. (1658085)
1991
26
Hepatoportal sclerosis in childhood. (2421592)
1986
27
Hepatoportal sclerosis in childhood: a mimic of extrahepatic portal vein obstruction. (7252729)
1981
28
Hepatoportal sclerosis--its relationship to intrahepatic portal venous thrombosis. (429020)
1979
29
Extra- and intrahepatic portal hypertension without cirrhosis (hepatoportal sclerosis). (5833586)
1965

Variations for Hepatoportal Sclerosis

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Expression for genes affiliated with Hepatoportal Sclerosis

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Search GEO for disease gene expression data for Hepatoportal Sclerosis.

Pathways for genes affiliated with Hepatoportal Sclerosis

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GO Terms for genes affiliated with Hepatoportal Sclerosis

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Cellular components related to Hepatoportal Sclerosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056158.6ACE, F2, GPT

Molecular functions related to Hepatoportal Sclerosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1peptidase activityGO:00082339.1ACE, F2

Sources for Hepatoportal Sclerosis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet