MCID: HPT009
MIFTS: 48

Hepatopulmonary Syndrome malady

Categories: Gastrointestinal diseases, Liver diseases

Aliases & Classifications for Hepatopulmonary Syndrome

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Aliases & Descriptions for Hepatopulmonary Syndrome:

Name: Hepatopulmonary Syndrome 11 50 39 13 68

Classifications:



External Ids:

Disease Ontology11 DOID:900
ICD1030 K76.81
SNOMED-CT62 371067004
ICD9CM32 573.5
MeSH39 D020065

Summaries for Hepatopulmonary Syndrome

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Wikipedia:71 In medicine, hepatopulmonary syndrome is a syndrome of shortness of breath and hypoxemia (low oxygen... more...

MalaCards based summary: Hepatopulmonary Syndrome is related to scrub typhus and unilateral hyperactive labyrinth, and has symptoms including hemoptysis and hepatomegaly. An important gene associated with Hepatopulmonary Syndrome is ALB (Albumin), and among its related pathways are Effects of nitric oxide and NO-dependent CFTR activation (normal and CF). Affiliated tissues include liver, lung and endothelial, and related mouse phenotypes are adipose tissue and neoplasm.

Related Diseases for Hepatopulmonary Syndrome

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Diseases related to Hepatopulmonary Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 123)
idRelated DiseaseScoreTop Affiliating Genes
1scrub typhus10.5ALB, TNF
2unilateral hyperactive labyrinth10.5ALB, EDNRB
3transient refractive change10.5EDN1, NOS3
4cartilage disease10.4ALB, TNF
5breast reconstruction10.4EDN1, NOS2
6gender identity disorder10.4ALB, NOS2, NOS3
7hydromyelia10.4NOS3, VEGFA
8emphysematous cholecystitis10.4NOS2, VEGFA
9retinitis pigmentosa 7010.4ALB, VEGFA
10hole retinal cyst10.4ALB, VEGFA
11mental depression10.3EDN1, HMOX1, NOS3
12poikiloderma with neutropenia10.3EDN1, NOS2, NOS3
13variola minor10.3ALB, NOS2, TNF
14ileocolitis10.3NOS3, TNF
15atypical follicular adenoma10.3ALB, NOS2, TNF
16extrahepatic cholestasis10.3ALB, EDN1, TNF
17scleral disease10.3ALB, TNF
18liver disease10.3
19diabetic encephalopathy10.3EDN1, NOS3, TNF
20frontal sinus cancer10.3ALB, EDN1, TNF
21angiomyolipoma10.2ALB, NOS2, TNF
22common wart10.2ALB, EDN1, TNF
23rectum leiomyosarcoma10.2ALB, EDNRB, TNF
24periampullary adenoma10.2EDN1, NOS3, TNF
25gingivitis10.2ALB, EDN1, TNF
26lymphedema10.2ALB, EDN1, TNF
27perianal skin paget's disease10.2ALB, EDNRB, TNF
28atrophic rhinitis10.2ALB, HMOX1, VEGFA
29pylorus cancer10.2ALB, VEGFA
30autoimmune polyendocrine syndrome10.2TNF, VEGFA
31lethal congenital contractural syndrome 210.2EDN1, NOS3, VEGFA
32acute myeloblastic leukemia without maturation10.2EDN1, NOS3, VEGFA
33fundus dystrophy10.2ALB, EDN1, TNF
34preeclampsia/eclampsia 110.2EDN1, NOS3, VEGFA
35hepatitis10.2
36portal hypertension10.2
37ovarian mucinous cystadenocarcinoma10.2AKT1, HMOX1, TNF
38parotid disease10.2EDN1, VWF
39scn8a encephalopathy10.2NOS2, TNF, VEGFA
40cutaneous leishmaniasis10.1EDN1, TNF, VEGFA
41liver cirrhosis10.1
42serpiginous choroiditis10.1ALB, EDNRA
43transvestism10.1EDN1, TNF
44angioedema10.1ALB, HMOX1, NOS2, TNF
45pulpitis10.1ALB, HMOX1, VWF
46macrocephaly mesodermal hamartoma spectrum10.1EDN1, VWF
47craniosynostosis10.1ALB, EDN1, NOS3, TNF
48spinal canal and spinal cord meningioma10.1EDN1, NOS2, NOS3, TNF
49endotheliitis10.1
50t-cell lymphoma 1a10.1TNF, VEGFA

Graphical network of the top 20 diseases related to Hepatopulmonary Syndrome:



Diseases related to hepatopulmonary syndrome

Symptoms & Phenotypes for Hepatopulmonary Syndrome

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UMLS symptoms related to Hepatopulmonary Syndrome:


hemoptysis, hepatomegaly

MGI Mouse Phenotypes related to Hepatopulmonary Syndrome according to GeneCards Suite gene sharing:

41 (show all 21)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053758.8AKT1, HMOX1, NOS2, NOS3, TNF
2MP:00020068.7AKT1, ALB, EDNRB, NOS2, TNF, VEGFA
3MP:00053898.2AKT1, HMOX1, NOS2, NOS3, NR0B2, TNF
4MP:00053918.2EDNRA, EDNRB, NOS2, NOS3, TNF, VEGFA
5MP:00053828.1EDN1, EDNRA, EDNRB, NOS2, TNF, VEGFA
6MP:00053707.9AKT1, ALB, HMOX1, NOS2, NOS3, NR0B2
7MP:00028737.7AKT1, ALB, EDN1, EDNRA, NOS3, NR0B2
8MP:00053887.6AKT1, EDNRA, EDNRB, HMOX1, NOS2, NOS3
9MP:00053907.5AKT1, EDN1, EDNRA, EDNRB, NOS2, NOS3
10MP:00053677.1ALB, EDN1, EDNRA, EDNRB, HMOX1, NOS2
11MP:00053977.1AKT1, EDNRA, HMOX1, NOS2, NOS3, TNF
12MP:00036316.7AKT1, EDN1, EDNRA, EDNRB, NOS2, NOS3
13MP:00053786.5AKT1, EDN1, EDNRA, EDNRB, HMOX1, NOS2
14MP:00053696.5AKT1, ALB, CAV3, EDN1, EDNRA, EDNRB
15MP:00053796.5AKT1, ALB, EDN1, EDNRA, EDNRB, HMOX1
16MP:00053876.3AKT1, CAV3, EDNRA, EDNRB, HMOX1, NOS2
17MP:00107686.2AKT1, ALB, EDN1, EDNRA, EDNRB, HMOX1
18MP:00053846.1AKT1, ALB, CAV3, EDNRA, EDNRB, HMOX1
19MP:00053816.1ALB, EDN1, EDNRA, EDNRB, NOS2, NOS3
20MP:00053855.8AKT1, CAV3, EDN1, EDNRA, EDNRB, HMOX1
21MP:00053765.0AKT1, ALB, CAV3, EDN1, EDNRA, EDNRB

Drugs & Therapeutics for Hepatopulmonary Syndrome

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Drugs for Hepatopulmonary Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 45)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Carvedilolapproved, investigationalPhase 416372956-09-32585
Synonyms:
(+-)-1-(Carbazol-4-yloxy)-3-((2-(O-methoxyphenoxy)ethyl)amino)-2-propanol
(+-)-1-(Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol
(+-)-1-Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol
(+/-)-1-(Carbazol-4-yloxy)-3-[[2-(o-methoxyphenoxy)ethyl]amino]-2-propanol
1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol
1-(9H-carbazol-4-yloxy)-3-[(2-{[2-(methyloxy)phenyl]oxy}ethyl)amino]propan-2-ol
1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol
1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol
107741-96-8
72956-09-3
AB1004830
AC-1641
AC1L1E0B
Artist
Artist (TN)
Atlana Pharma brand of carvedilol
BM 14190
BM-14-190
BM-14.190
BM-14190
BRD-A10977446-001-04-8
BRD-A10977446-045-01-1
Bio-0014
C043211
C06875
C2260
C24H26N2O4
CHEBI:3441
CHEMBL723
CID2585
CPD000449280
Carvedilol
Carvedilol (JAN/USAN/INN)
Carvedilol [USAN:INN:BAN:JAN]
Carvedilolum
Carvedilolum [Latin]
Coreg
Coreg (TN)
Coreg CR
Coropres
Coropress
D00255
DB01136
DQ 2466
DQ-2466
Dibloc
 
Dilatrend
EG-P042
Eucardic
GlaxoSmithKline brand of carvedilol
HMS2051N03
HMS2089B09
HMS2093E12
HSDB 7044
I06-0064
I06-1477
KBio2_002145
KBio2_004713
KBio2_007281
KBio3_002323
KBioGR_001252
KBioSS_002145
Kredex
L001243
LS-121875
Lakeside brand of carvedilol
MLS000758299
MLS000759508
MLS001424092
MolPort-003-666-814
NCGC00167832-01
NCGC00167832-02
NCGC00167832-03
Querto
Roche brand of carvedilol
SAM001246736
SAM001247021
SK&F-105517
SKF 105517
SMR000449280
SPBio_001885
STK621453
Spectrum2_001673
Spectrum3_001182
Spectrum4_000636
Spectrum5_001436
Spectrum_001665
TL8005080
UNII-0K47UL67F2
carvedilol
carvedilol, (+-)-isomer
carvedilol, (R)-isomer
carvedilol, (S)-isomer
carvedilol, 14C-labeled
2Vasodilator AgentsPhase 4, Phase 13438
3Liver ExtractsPhase 4, Phase 2, Phase 13868
4PolygelinePhase 412
5Neurotransmitter AgentsPhase 417734
6Adrenergic beta-AntagonistsPhase 41154
7Antihypertensive AgentsPhase 4, Phase 24095
8Adrenergic alpha-1 Receptor AntagonistsPhase 4470
9Adrenergic AgentsPhase 45140
10Adrenergic alpha-AntagonistsPhase 4727
11Adrenergic AntagonistsPhase 41535
12
NorfloxacinapprovedPhase 21570458-96-74539
Synonyms:
1,4-Dihydro-1-ethyl-6-fluoro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
1-Ethyl-6-fluor-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-chinolincarbonsaeure
1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-[1-piperazinyl]-3-quinoline- carboxylic acid
1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
1-ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylic acid
1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
68077-27-0
70458-96-7
AC-6855
AC1L1IE1
AKOS000417391
AM 0715
AM 715
AM-0715
AM-715
AM0715
ARONIS24170
BB_SC-0063
BCBcMAP01_000218
BIDD:GT0725
BPBio1_000289
BRD-K11196887-001-05-5
BRN 0567897
BSPBio_000261
BSPBio_002107
Baccidal
Barazan
C06687
C16H18FN3O3
CAS-70458-96-7
CCRIS 6302
CHEBI:100246
CHEMBL9
CID4539
Chibroxin
Chibroxin, MK-366, Baccidal, Sebercim, Zoroxin, Norfloxacin
D00210
D009643
DB01059
DivK1c_000084
EINECS 274-614-4
Fulgram
HMS1568N03
HMS1920B16
HMS2090F03
HMS2091J16
HMS500E06
I14-0947
IDI1_000084
KBio1_000084
KBio2_001497
KBio2_004065
 
KBio2_006633
KBio3_001607
KBioGR_000866
KBioSS_001497
LS-141592
Lexinor
MK 0366
MK 366
MK-0366
MK-366
MK0366
MK366
MLS000069650
Merck Brand of Norfloxacin
MolPort-001-738-625
NCGC00016916-01
NCGC00016916-02
NCGC00021725-03
NCGC00021725-04
NFLX
NINDS_000084
Norflo
Norfloxacin (JP15/USP/INN)
Norfloxacin Merck Brand
Norfloxacin [USAN:BAN:INN:JAN]
Norfloxacine
Norfloxacine [INN-French]
Norfloxacino
Norfloxacino [INN-Spanish]
Norfloxacinum
Norfloxacinum [INN-Latin]
Noroxin
Noroxin (TN)
Oprea1_375152
Prestwick0_000221
Prestwick1_000221
Prestwick2_000221
Prestwick3_000221
Prestwick_633
S1509_Selleck
SMP1_000216
SMR000058200
SPBio_001173
SPBio_002182
SPECTRUM1500440
STK177250
Sebercim
Spectrum2_001017
Spectrum3_000524
Spectrum4_000453
Spectrum5_001154
Spectrum_001017
UNII-N0F8P22L1P
nchembio820-comp2
norfloxacin
13
Sorafenibapproved, investigationalPhase 2692284461-73-0216239, 406563
Synonyms:
284461-73-0
4(4-{3-[4-Chloro-3-(trifluoromethyl)phenyl]ureido}phenoxy)-N(sup 2)-methylpyridine-2-carboxamide
4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide
4-(4-(3-(4-chloro-3-trifluoromethylphenyl)ureido)phenoxy)pyridine-2-carboxyllic acid methyamide-4-methylbenzenesulfonate
4-(4-{3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido}phenoxy)-N(sup 2)-methylpyridine-2-carboxamide
4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide
4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide
4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide
4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide
4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE
AB1004622
AC-1674
AC1L50CF
BAX
BAY 43-9006
BAY 43-9006 (free base)
BAY 43-9006 tosylate salt
BAY 439006
BAY 54-9085 (tosylate salt)
BAY-43-0006
BAY-43-9006
BAY-54-9085
BAY43-9006
BRD-K23984367-001-01-8
Bio-0100
CHEBI:47228
CHEBI:50924
CHEMBL1336
CID216239
 
D08524
DB00398
DB07438
EN002709
I06-0856
K00597a
Kinome_766
LS-186067
LS-187021
LS-187788
MolPort-003-850-270
N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea
N-(4-Chloro-3-(trifluoromethyl)phenyl)-n'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea
N-(4-chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcar bamoyl)-4-pyridyloxy)phenyl)urea
N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[4-[2-(N-methylcarbamoyl)-4-pyridyloxy]phenyl]urea
NCGC00167488-01
NSC-724772
NSC747971
Nexavar
STK627350
Sorafenib
Sorafenib (INN)
Sorafenib [INN]
Sorafenib tosylate
Sorafenibum
UNII-9ZOQ3TZI87
ZINC01493878
nchembio.117-comp17
sorafenib
sorafenibum
14
Bosentanapproved, investigationalPhase 2103147536-97-8104865
Synonyms:
-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]benzenesulfonamide
147536-97-8
174227-18-0
4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide
4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl)benzenesulfornamide
4-t-butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide
4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide
4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide
AC-148
AC1L2XN2
Actelion
Bosentan
Bosentan (INN)
Bosentan [USAN:INN:BAN]
Bosentan hydrate
C27H29N5O6S
CHEBI:51450
CHEMBL957
CID104865
D07538
DB00559
 
EN002863
HMS2090N14
I06-1873
KS-5062
L001086
LS-31532
MolPort-003-845-300
NCGC00167440-01
PDSP1_001731
PDSP2_001714
Ro 47-0203
Ro 47-0203/039
Ro-47-0203
Ro-47-0203/029
Ro-47-0203/039
TL8001039
Tracleer
UNII-XUL93R30K2
bosentan
bosentanum
bosentán
p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide
p-tert-Butyl-N-[6-(2-hydroxyethoxy)
15
Folic Acidapproved, nutraceutical, vet_approvedPhase 2427959-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
16
Nicotinamideapproved, NutraceuticalPhase 290298-92-0936
Synonyms:
.beta.-Pyridinecarboxamide
11032-50-1
123574-63-0
1yc5
3 Pyridinecarboxamide
3-Carbamoylpyridine
3-Pyridinecarboxamide
3-Pyridinecarboxylic acid amide
37321-14-5
47865U_SUPELCO
55600-01-6
63748-44-7
72340_FLUKA
72340_SIGMA
72347_FLUKA
78731-47-2
98-92-0
A186B02E-6C70-4E54-9739-79398D439AAA
AC-907/25014114
AC1L1ACZ
AC1Q4ZFV
AI3-02906
Acid amide
Amid kyseliny nikotinove
Amid kyseliny nikotinove [Czech]
Amide PP
Aminicotin
Amixicotyn
Amnicotin
Astra Brand of Niacinamide
Austrovit PP
B 3, Vitamin
B3, Vitamin
BB_NC-2290
Benicot
C00153
C6H6N2O
CCRIS 1901
CHEBI:17154
CHEMBL1140
CID936
CPD000058212
D00036
D009536
DB02701
DEA No. 1405
Delonin Amide
Delonin amide
Dipegyl
Dipigyl
EINECS 202-713-4
EINECS 234-265-0
Endobion
Enduramide
Factor pp
HMS2052M21
HMS2090B05
HMS2093H03
HSDB 1237
Hansamid
I02-1741
I02-2250
InChI=1/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9
Inovitan PP
Jenapharm Brand of Niacinamide
Jenapharm, Nicotinsaureamid
LS-2051
MLS000069714
Mediatric
Merck Brand of Niacinamide
MolMap_000061
MolPort-001-783-876
N0078
N0636_SIGMA
N2142_SIGMA
N3376_SIGMA
N5535_SIAL
NAM
NCGC00093354-03
NCGC00093354-04
NSC 13128
NSC13128
NSC27452
Nandervit-N
Niacevit
Niacinamide
Niacinamide (USP)
Niacinamide Astra Brand
Niacinamide Jenapharm Brand
Niacinamide Merck Brand
 
Niacinamide Pharmagenix Brand
Niacinamide [USAN]
Niacinamide, Nicotinic acid amide, Nicotinamide
Niacotinamide
Niamide
Niavit PP
Nicamide
Nicamina
Nicamindon
Nicasir
Nicobion
Nicofort
Nicogen
Nicomidol
Nicosan 2
Nicosylamide
Nicota
Nicotamide
Nicotilamide
Nicotililamido
Nicotinamid
Nicotinamida
Nicotinamida [INN-Spanish]
Nicotinamide
Nicotinamide (JP15/INN)
Nicotinamide (Niacinamide)
Nicotinamide, niacin, vitamin B3
Nicotinamide-carbonyl-14C
Nicotinamidum
Nicotinamidum [INN-Latin]
Nicotine acid amide
Nicotine amide
Nicotinic acid amide
Nicotinic amide
Nicotinsaeureamid
Nicotinsaureamid
Nicotinsaureamid Jenapharm
Nicotinsaureamid [German]
Nicotol
Nicotylamide
Nicotylamidum
Nicovel
Nicovit
Nicovitina
Nicovitol
Nicozymin
Nictoamide
Nikasan
Nikazan
Niko-tamin
Nikotinamid
Nikotinsaeureamid
Nikotinsaeureamid [German]
Niocinamide
Niozymin
PP-Faktor
Papulex
Pelmin
Pelmine
Pelonin amide
Pharmagenix Brand of Niacinamide
Propamine A
Pyridine-3-carboxylic acid amide
S1899_Selleck
SAM001246860
SGCUT00176
SMR000058212
Savacotyl
UNII-25X51I8RD4
Vi-Nicotyl
Vi-noctyl
Vitamin B
Vitamin B (VAN)
Vitamin B 3
Vitamin B3 amide
Vitamin H1
Vitamin PP
WLN: T6NJ CVZ
Witamina PP
ZINC00005878
b-Pyridinecarboxamide
beta-Pyridinecarboxamide
bmse000281
m-(Aminocarbonyl)pyridine
nchembio.154-comp4
nchembio.73-comp6
niacin - Vitamin B3
niacinamide
nicotinamide
pyridine-3-carboxamide
to_000073
vitamin PP
17
Niacinapproved, investigational, nutraceuticalPhase 290659-67-6938
Synonyms:
3-Carboxylpyridine
3-Carboxypyridine
3-Pyridinecarboxylate
3-Pyridinecarboxylic acid
3-Pyridylcarboxylate
3-Pyridylcarboxylic acid
3-carboxypyridine
Acide Nicotinique
Acido nicotinico
Acidum Nicotinicum
Akotin
Anti-pellagra vitamin
Apelagrin
Daskil
Efacin
Enduracin
Linic
M-Pyridinecarboxylic Acid
Niac
Niacin
Niacine
Niacor
Nicacid
Nicamin
Nicangin
 
Nico-Span
Nicobid
Nicocap
Nicodelmine
Nicolar
Niconacid
Nicosan 3
Nicotinate
Nicotinic Acid
Nicotinic acid
Nicotinipca
Nicyl
Nikotinsaeure
Nyclin
P.P. factor
PP Factor
Pellagra preventive factor
Pellagrin
Pelonin
Pyridine-beta-carboxylic acid
Slo-niacin
Vitamin B3
Wampocap
beta-Pyridinecarboxylic acid
pyridine-β-carboxylic acid
β-pyridinecarboxylic acid
18Anti-Infective AgentsPhase 221402
19Anti-Bacterial AgentsPhase 210884
20Cytochrome P-450 Enzyme InhibitorsPhase 23822
21Cytochrome P-450 CYP1A2 InhibitorsPhase 2553
22Topoisomerase InhibitorsPhase 24945
23Trace ElementsPhase 25802
24cadexomer iodinePhase 2514
25Vitamin B ComplexPhase 24229
26Protein Kinase InhibitorsPhase 23612
27
IodinePhase 25467553-56-2807
Synonyms:
I2
Iode
Iodine-molecule
 
Iodio
Iodum
Jod
Jood
Tincture iodine
28MicronutrientsPhase 25802
29VitaminsPhase 25095
30Nicotinic AcidsPhase 2906
31Endothelin Receptor AntagonistsPhase 2215
32Vitamin B9NutraceuticalPhase 24279
33Vitamin B3NutraceuticalPhase 2906
34FolateNutraceuticalPhase 24279
35
Pentoxifyllineapproved, investigationalPhase 1996493-05-64740
Synonyms:
1,2,3,6-Tetrahydro-3,7-dimethyl-1-(5-oxohexyl)-2,6-purindion
1-(5-Oxohexyl)-3,7-dimethylxanthine
1-(5-Oxohexyl)theobromine
2a3c
3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione
3,7-Dimethyl-1-(5-oxo-hexyl)-3,7-dihydro-purine-2,6-dione
3,7-Dimethyl-1-(5-oxohexyl) xantine
3,7-Dimethyl-1-(5-oxohexyl)-1H,3H-purin-2,6-dione
3,7-Dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione
3,7-Dimethyl-1-(5-oxohexyl)xanthine
3,7-Dimethyl-1-(5-oxohexyl)xantine
3,7-dimethyl-1-(5-oxohexyl)purine-2,6-dione
5-26-14-00081 (Beilstein Handbook Reference)
6493-05-6
AB00052363
AC1L1IUN
AKOS000541484
Agapurin
Agapurin Retard
Azupentat
BAS 00897429
BB_SC-2111
BIDD:GT0174
BL 191
BL-191
BL191
BPBio1_000167
BRD-K57569181-001-05-1
BRN 0558929
BSPBio_000151
BSPBio_003439
C07424
C13H18N4O3
CAS-1677687
CCRIS 6832
CHEMBL628
CID4740
CPD000035998
D00501
D010431
DB00806
Dimethyloxohexylxanthine
DivK1c_000729
Durapental
EHT 0201
EHT-0201
EHT-201
EHT0201
EINECS 229-374-5
EU-0100936
HMS1568H13
HMS1922E16
HMS2051N06
HMS2090H13
HMS2093G21
HMS502E11
Hemovas
I06-1592
IDI1_000729
IN1161
Ikomio
KBio1_000729
KBio2_001924
KBio2_004492
KBio2_007060
KBio3_002942
KBioGR_000893
KBioSS_001924
LS-149385
 
Lopac-P-1784
Lopac0_000936
MLS000079026
MLS000758298
MLS001201764
MolPort-001-823-263
NCGC00015801-01
NCGC00015801-02
NCGC00015801-04
NCGC00015801-10
NCGC00067069-02
NCGC00067069-03
NCGC00067069-04
NCGC00067069-05
NCGC00178062-01
NCGC00178062-02
NINDS_000729
NSC 637086
NSC637086
Oxpentifylline
P 1784
PDSP1_001015
PDSP2_000999
PENTOXYPHYLINE
PNX
Pentoxifilina
Pentoxifilina [INN-Spanish]
Pentoxifyllin
Pentoxifylline
Pentoxifylline (JAN/USP/INN)
Pentoxifylline [USAN:INN:JAN]
Pentoxifyllinum
Pentoxifyllinum [INN-Latin]
Pentoxil
Pentoxil (TN)
Pentoxiphyllin
Pentoxiphylline
Pentoxiphyllium
Pentoxyfylline
Pentoxyphyllin
Pentoxyphylline
Prestwick0_000196
Prestwick1_000196
Prestwick2_000196
Prestwick3_000196
Prestwick_608
Px
Ralofect
Rentylin
SAM001247011
SMR000035998
SPBio_001221
SPBio_002072
SPECTRUM1503611
SR-01000075641-4
STK177321
Spectrum2_001181
Spectrum3_001820
Spectrum4_000227
Spectrum5_001161
Spectrum_001444
Torental
Trental
Trental (TN)
UNII-SD6QCT3TSU
Vasofirin
Vazofirin
ZINC01530776
cis-9-Octadecenoyl coenzyme A
pentoxifylline
36Radiation-Protective AgentsPhase 1466
37Platelet Aggregation InhibitorsPhase 12419
38Protective AgentsPhase 17190
39Phosphodiesterase InhibitorsPhase 11254
40AntioxidantsPhase 12928
41
Rifaximinapproved, investigational10180621-81-46436173
Synonyms:
(2S,16Z,18E,20S,21S,22R,23R,24R,25S,26S,27S,28E)-5,6,21,23,25 Pentahydroxy-27-methoxy-2,4,11,16,20,22,24,26-octamethyl-2,7-(epoxypentadeca(1,11,13)trienimino)benzofuro(4,5-e)pyrido(1,2-a)benzimidazole-1,15(2H)-dione, 25-acetate
4-Deoxy-4'-methylpyrido(1',2'-1,2)imidazo(5,4-c)rifamycin SV
4-deoxy-4'-methylpyrido(1',2'-1,2)imidazo(5,4C)rifamycin
80621-81-4
88747-56-2
AC-19112
BRN 3584528
Bio-0556
C43H51N3O11
CHEMBL1617
D02554
DB01220
Fatroximin
Flonorm
L 105
L 105 (Ansamacrolide antibiotic)
L 105SV
LS-178059
LS-64147
Lormyx
Lumenax
MLS000759430
Normix
RedActiv
 
Rifacol
Rifamixin
Rifamycin L 105
Rifamycin L 105SV
Rifaxidin
Rifaximin
Rifaximin (USAN/INN)
Rifaximin [USAN:INN]
Rifaximina
Rifaximina [Spanish]
Rifaximine
Rifaximine [French]
Rifaximinum
Rifaximinum [Latin]
Rifaximinun
Rifaxin
Ritacol
S1790_Selleck
SMR000466324
Spiraxin
UNII-L36O5T016N
Xifaxan
Xifaxan, Rifacol, Fatroximin, Rifaximin
Xifaxsan
Xifaxsan (TN)
alpha-0817185
42Rifamycins97
43Nucleic Acid Synthesis Inhibitors4855
44Gastrointestinal Agents8109
45rifamycin SV97

Interventional clinical trials:

idNameStatusNCT IDPhase
1Echocardiographic Assessment of Intrapulmonary Vasodilatation: Agitated Saline Versus PolygelineUnknown statusNCT00343122Phase 4
2Early Precise Diagnosis and Intervention of CPT Based on a Noninvasive 3D-vHPSRecruitingNCT02925975Phase 4
3A Pilot Study of Norfloxacin for Hepatopulmonary SyndromeCompletedNCT00362752Phase 2
4Sorafenib for Hepatopulmonary SyndromeRecruitingNCT02021929Phase 2
5Bosentan for Treatment of Hepatopulmonary Syndrome in Patients With Liver CirrhosisTerminatedNCT01518595Phase 2
6Pilot Study of Pentoxifylline for Hepatopulmonary SyndromeTerminatedNCT00593658Phase 1
7Effect of Transjugular Intrahepatic Portosystemic Shunt on Oxygenation in Cirrhotic Patients With Hepatopulmonary SyndromeUnknown statusNCT02148536
8Efficacy of Pentoxifylline and Rifaximin Combination in Pentoxifylline Refractory Clinical and Subclinical Hepatopulmonary SyndromeUnknown statusNCT01676597

Search NIH Clinical Center for Hepatopulmonary Syndrome


Cochrane evidence based reviews: hepatopulmonary syndrome

Genetic Tests for Hepatopulmonary Syndrome

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Anatomical Context for Hepatopulmonary Syndrome

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MalaCards organs/tissues related to Hepatopulmonary Syndrome:

36
Liver, Lung, Endothelial, Brain, Smooth muscle, Monocytes, Bone

Publications for Hepatopulmonary Syndrome

About this section

Articles related to Hepatopulmonary Syndrome:

(show top 50)    (show all 469)
idTitleAuthorsYear
1
CXCR2 is involved in pulmonary intravascular macrophage accumulation and angiogenesis in a rat model of hepatopulmonary syndrome. (27879294)
2017
2
Live donor liver transplantation for a child presented with severe hepatopulmonary syndrome and nodular liver lesions due to Abernethy malformation. (28078819)
2017
3
Severe Hepatopulmonary Syndrome in an Adolescent Patient with Non-Cirrhotic Portal Fibrosis. (28008407)
2016
4
Prevalence, Severity, and Prognostic Effect of Hepatopulmonary Syndrome in Liver Transplant Candidates. (27020907)
2016
5
Nitric oxide metabolites, nitrative stress, and paraoxonase activity in hepatopulmonary syndrome. (26051624)
2016
6
MIR196A2 rs11614913 CA >A T polymorphism correlates with an increased risk of hepatopulmonary syndrome in liver cirrhosis: a case-control study in China. (27509319)
2016
7
Mechanical characteristics of the pulmonary artery in beagle dogs with hepatopulmonary syndrome and portopulmonary hypertension. (26870333)
2016
8
Down-regulation of common NFI_B-iNOS pathway by chronic Thalidomide treatment improves Hepatopulmonary Syndrome and Muscle Wasting in rats with Biliary Cirrhosis. (28009008)
2016
9
Frequency of Hepatopulmonary Syndrome (HPS) Among Patients With Liver Cirrhosis: A Letter to Editor. (27148388)
2016
10
CT Scan Does Not Differentiate Patients with Hepatopulmonary Syndrome from Other Patients with Liver Disease. (27384058)
2016
11
A Case of Hepatopulmonary Syndrome. (27134920)
2016
12
Hepatopulmonary Syndrome: A Brief Review. (27352437)
2016
13
Autoimmune hepatitis in a child presenting with hepatopulmonary syndrome (HPS). (26992455)
2016
14
Quercetin alleviates pulmonary angiogenesis in a rat model of hepatopulmonary syndrome. (27383124)
2016
15
A case report of suspected hepatopulmonary syndrome secondary to ductal plate malformation with chronic active hepatitis in a dog. (26616155)
2016
16
Inhibition of autophagy ameliorates pulmonary microvascular dilation and PMVECs excessive proliferation in rat experimental hepatopulmonary syndrome. (27480323)
2016
17
Hepatopulmonary Syndrome and Liver Transplantation: A Recent Review of the Literature. (27047772)
2016
18
Hepatopulmonary Syndrome in Patients With Cystic Fibrosis and Liver Disease. (26867851)
2016
19
The role of splenic reservoir monocytes in pulmonary vascular monocyte accumulation in experimental hepatopulmonary syndrome. (27029414)
2016
20
International Liver Transplant Society Practice Guidelines: Diagnosis and Management of Hepatopulmonary Syndrome and Portopulmonary Hypertension. (27326810)
2016
21
Response to Sildenafil in a Patient With Coexisting Post-Liver Transplant Portopulmonary Hypertension and Hepatopulmonary Syndrome. (27001306)
2016
22
CHARACTER AND FREQUENCY OF THE VARIATIONS OF CO- AND POLYMORBID SYNTROPIC EXTRAHEPATIC LESIONS AND THEIR DEPENDENCE ON THE HEPATOPULMONARY SYNDROME SEVERITY DEGREE IN CIRRHOTIC PATIENTS. (28009313)
2016
23
Hepatopulmonary syndrome: What we know and what we would like to know. (27433086)
2016
24
Paediatric intrapulmonary right-to-left shunt caused by hepatopulmonary syndrome. (27165716)
2016
25
The Role of TEE in Diagnosing Hepatopulmonary Syndrome and Cryptogenic Cirrhosis. (27656299)
2016
26
Serum bile acids in patients with hepatopulmonary syndrome. (27951601)
2016
27
Aggravation of hepatopulmonary syndrome after sildenafil treatment in a patient with coexisting portopulmonary hypertension. (25653708)
2015
28
The involvement of aquaporin 1 in the hepatopulmonary syndrome rat serum-induced migration of pulmonary arterial smooth muscle cells via the p38-MAPK pathway. (26315345)
2015
29
MicroRNA-101 inhibits proliferation of pulmonary microvascular endothelial cells in a rat model of hepatopulmonary syndrome by targeting the JAK2/STAT3 signaling pathway. (26498873)
2015
30
Hepatopulmonary Syndrome Is a Frequent Cause of Dyspnea in the Short Telomere Disorders. (26158642)
2015
31
Role of Transjugular Intrahepatic Portosystemic Shunts in the Management of Hepatopulmonary Syndrome: A Systemic Literature Review. (26074026)
2015
32
Clinical characteristics, predictors, and survival among patients with hepatopulmonary syndrome. (25864216)
2015
33
Extracorporeal membrane oxygenation after liver transplantation in a patient with hepatopulmonary syndrome and an atrial septal defect. (25837880)
2015
34
Rosuvastatin improves hepatopulmonary syndrome through inhibition of inflammatory angiogenesis of lung. (25940601)
2015
35
MicroRNA-199a-5p Regulates the Proliferation of Pulmonary Microvascular Endothelial Cells in Hepatopulmonary Syndrome. (26430741)
2015
36
Hepatopulmonary syndrome and portopulmonary hypertension: recent knowledge in pathogenesis and overview of clinical assessment. (25627425)
2015
37
Prevalence and impact on survival of hepatopulmonary syndrome and cirrhotic cardiomyopathy in a cohort of cirrhotic patients. (25974637)
2015
38
Variability of Oxygenation in Possible Hepatopulmonary Syndrome: Effects of Requiring Two Abnormal Arterial Blood Gas Results for Diagnosis. (25586084)
2015
39
Congenital extrahepatic portosystemic shunt: an underdiagnosed but treatable cause of hepatopulmonary syndrome. (26311567)
2015
40
Brain abscess in hepatopulmonary syndrome associated with biliary atresia. (26711920)
2015
41
Hepatopulmonary Syndrome. (25732713)
2015
42
Proposed management algorithm for severe hypoxemia after liver transplantation in the hepatopulmonary syndrome. (25649047)
2015
43
Familial hepatopulmonary syndrome in common variable immunodeficiency. (25708586)
2015
44
Accurate measurement of the normality values of macroaggregated albumin lung perfusion scan in hepatopulmonary syndrome. (26184840)
2015
45
A 45-Year-Old Undiagnosed Cirrhotic Patient with Hepatopulmonary Syndrome as First Presentation: A Case Report. (26489790)
2015
46
Response to 'The role of macroaggregated albumin lung perfusion scan in hepatopulmonary syndrome: are we ready to draw conclusions?' (25761922)
2015
47
CT Pulmonary Angiography Features of a Hepatopulmonary Syndrome. (26175599)
2015
48
Exercise capacity of cirrhotic patients with hepatopulmonary syndrome. (25864217)
2015
49
The role of macroaggregated albumin lung perfusion scan in hepatopulmonary syndrome: are we ready to draw conclusions? (25688443)
2015
50
Requirement of miR-9-dependent regulation of Myocd in PASMCs phenotypic modulation and proliferation induced by hepatopulmonary syndrome rat serum. (26147104)
2015

Variations for Hepatopulmonary Syndrome

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Expression for genes affiliated with Hepatopulmonary Syndrome

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Search GEO for disease gene expression data for Hepatopulmonary Syndrome.

Pathways for genes affiliated with Hepatopulmonary Syndrome

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Pathways related to Hepatopulmonary Syndrome according to GeneCards Suite gene sharing:

(show all 29)
idSuper pathwaysScoreTop Affiliating Genes
19.8NOS2, NOS3
29.8NOS2, NOS3
39.4AKT1, NOS2, NOS3
49.4EDN1, NOS3, VEGFA
59.4AKT1, NOS3, TNF
69.4AKT1, EDN1, TNF
79.4AKT1, EDN1, TNF
8
Show member pathways
9.3AKT1, NOS3, VEGFA
9
Show member pathways
9.3AKT1, NOS3, VEGFA
10
Show member pathways
9.3HMOX1, NOS3, VWF
11
Show member pathways
9.2AKT1, EDN1, EDNRB, NOS3
129.2AKT1, NOS3, VWF
13
Show member pathways
9.1AKT1, NOS2, NOS3, TNF
149.0EDN1, EDNRA, EDNRB
15
Show member pathways
9.0AKT1, NOS2, NOS3, VEGFA
16
Show member pathways
9.0AKT1, NOS3, TNF, VEGFA
178.9AKT1, NOS2, TNF, VEGFA
188.7EDN1, EDNRA, EDNRB, NOS3
198.7AKT1, CAV3, TNF, VEGFA
208.7AKT1, NOS3, VEGFA, VWF
218.7EDNRA, EDNRB, NOS2, NOS3
228.7AKT1, EDN1, HMOX1, NOS2, VEGFA
238.7AKT1, EDN1, NOS3, TNF, VEGFA
24
Show member pathways
8.6AKT1, EDNRA, EDNRB, NOS3
258.6AKT1, EDN1, EDNRA, EDNRB
268.4AKT1, EDN1, HMOX1, NOS2, NOS3, VEGFA
27
Show member pathways
8.2AKT1, EDN1, EDNRA, NOS3, VEGFA
288.1AKT1, EDNRA, EDNRB, NOS2, VEGFA
29
Show member pathways
7.2AKT1, EDN1, EDNRA, EDNRB, NOS2, NOS3

GO Terms for genes affiliated with Hepatopulmonary Syndrome

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Cellular components related to Hepatopulmonary Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1caveolaGO:000590110.0CAV3, HMOX1, NOS3
2Weibel-Palade bodyGO:00330939.6EDN1, VWF
3platelet alpha granule lumenGO:00310939.3ALB, VEGFA, VWF
4membrane raftGO:00451218.9CAV3, EDNRA, EDNRB, TNF

Biological processes related to Hepatopulmonary Syndrome according to GeneCards Suite gene sharing:

(show top 50)    (show all 54)
idNameGO IDScoreTop Affiliating Genes
1epithelial fluid transportGO:004204510.6EDN1, EDNRB
2arginine catabolic processGO:000652710.6NOS2, NOS3
3negative regulation of cellular protein metabolic processGO:003226910.6EDN1, EDNRB
4nitric oxide mediated signal transductionGO:000726310.6NOS2, NOS3
5positive regulation of guanylate cyclase activityGO:003128410.6NOS2, NOS3
6positive regulation of chemokine biosynthetic processGO:004508010.6HMOX1, TNF
7regulation of systemic arterial blood pressure by endothelinGO:000310010.6EDN1, NOS3
8positive regulation of renal sodium excretionGO:003581510.5EDN1, EDNRB
9positive regulation of urine volumeGO:003581010.5EDN1, EDNRB
10regulation of pHGO:000688510.5EDN1, EDNRB
11response to fluid shear stressGO:003440510.4AKT1, NOS3
12negative regulation of calcium ion transportGO:005192610.4CAV3, NOS3
13cellular response to vascular endothelial growth factor stimulusGO:003592410.4AKT1, VEGFA
14positive regulation of blood vessel endothelial cell migrationGO:004353610.3AKT1, VEGFA
15positive regulation of protein complex assemblyGO:003133410.3TNF, VEGFA
16negative regulation of cell sizeGO:004579210.3AKT1, CAV3
17smooth muscle hyperplasiaGO:001480610.3HMOX1, NOS3
18positive regulation of vasodilationGO:004590910.3HMOX1, NOS2, NOS3
19cellular response to lipopolysaccharideGO:007122210.2EDNRB, NOS2, TNF
20positive regulation of smooth muscle cell proliferationGO:004866110.2EDN1, HMOX1, TNF
21positive regulation of angiogenesisGO:004576610.2HMOX1, NOS3, VEGFA
22nitric oxide biosynthetic processGO:000680910.2AKT1, NOS2, NOS3
23lipopolysaccharide-mediated signaling pathwayGO:003166310.2AKT1, NOS3, TNF
24artery smooth muscle contractionGO:001482410.1EDN1, EDNRA
25histamine secretionGO:000182110.1EDN1, EDNRA
26maternal process involved in parturitionGO:006013710.1EDN1, EDNRA
27negative regulation of cAMP biosynthetic processGO:003081810.1EDN1, EDNRA
28endothelin receptor signaling pathwayGO:008610010.1EDNRA, EDNRB
29enteric nervous system developmentGO:004848410.1EDNRA, EDNRB
30neural crest cell developmentGO:001403210.1EDN1, EDNRA
31positive regulation of nitric oxide biosynthetic processGO:004542910.1AKT1, EDN1, TNF
32positive regulation of sequence-specific DNA binding transcription factor activityGO:005109110.1AKT1, EDN1, TNF
33positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathwayGO:005148210.1EDN1, EDNRA
34positive regulation of odontogenesisGO:004248210.1EDN1, EDNRA
35positive regulation of MAP kinase activityGO:004340610.1EDN1, TNF, VEGFA
36regulation of epithelial cell proliferationGO:005067810.0EDNRA, EDNRB
37response to organic substanceGO:00100339.9AKT1, ALB, TNF
38positive regulation of peptidyl-serine phosphorylationGO:00331389.9AKT1, TNF, VEGFA
39platelet degranulationGO:00025769.9ALB, VEGFA, VWF
40vein smooth muscle contractionGO:00148269.9EDN1, EDNRB
41cellular response to hypoxiaGO:00714569.8AKT1, EDN1, HMOX1, VEGFA
42glucose transportGO:00157589.7AKT1, EDN1, EDNRA
43positive regulation of protein phosphorylationGO:00019349.6AKT1, EDNRB, TNF, VEGFA
44negative regulation of gene expressionGO:00106299.6AKT1, NOS2, NR0B2, TNF
45sensory perception of painGO:00192339.4EDN1, EDNRA, EDNRB
46in utero embryonic developmentGO:00017019.4EDN1, EDNRA, NOS3, VEGFA
47response to lipopolysaccharideGO:00324969.3EDN1, EDNRA, EDNRB, NOS2
48negative regulation of transcription from RNA polymerase II promoterGO:00001229.2EDN1, EDNRB, NR0B2, TNF, VEGFA
49positive regulation of cytosolic calcium ion concentrationGO:00072049.2CAV3, EDN1, EDNRA, EDNRB
50regulation of blood pressureGO:00082179.1EDN1, EDNRA, EDNRB, HMOX1, NOS3

Molecular functions related to Hepatopulmonary Syndrome according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1arginine bindingGO:003461810.7NOS2, NOS3
2FMN bindingGO:001018110.7NOS2, NOS3
3nitric-oxide synthase activityGO:000451710.7NOS2, NOS3
4heme bindingGO:002003710.4HMOX1, NOS2, NOS3
5endothelin receptor activityGO:000496210.2EDNRA, EDNRB
6enzyme bindingGO:00198999.8AKT1, ALB, CAV3, HMOX1
7tetrahydrobiopterin bindingGO:00346179.8NOS2, NOS3
8identical protein bindingGO:00428029.2AKT1, ALB, TNF, VEGFA, VWF
9protein homodimerization activityGO:00428038.3HMOX1, NOS2, NR0B2, VEGFA, VWF
10protein bindingGO:00055155.7AKT1, ALB, CAV3, EDN1, EDNRA, EDNRB

Sources for Hepatopulmonary Syndrome

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet