MCID: HPT070
MIFTS: 24

Hepatosplenic T-Cell Lymphoma malady

Cancer diseases, Blood diseases, Immune diseases, Liver diseases categories

Summaries for Hepatosplenic T-Cell Lymphoma

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32MalaCards
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MalaCards: Hepatosplenic T-Cell Lymphoma is related to inflammatory bowel disease and t-cell leukemia. An important gene associated with Hepatosplenic T-Cell Lymphoma is DPP4 (dipeptidyl-peptidase 4), and among its related pathways is Hematopoietic cell lineage. The compounds atorvastatin and rosiglitazone have been mentioned in the context of this disorder. Affiliated tissues include t cells.

Aliases & Classifications for Hepatosplenic T-Cell Lymphoma

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Sources:
48Orphanet, 60UMLS, 26ICD10 via Orphanet, 57SNOMED-CT via Orphanet, 61UMLS via Orphanet, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Blood diseases, Immune diseases, Liver diseases


Characteristics (Orphanet epidemiological data):

48
hepatosplenic t-cell lymphoma:
Age of onset: Adolescence / Young adulthood


Aliases & Descriptions:

hepatosplenic t-cell lymphoma 48 60


External Ids:

ICD10 via Orphanet26 C84.4
SNOMED-CT via Orphanet57 445406001
UMLS via Orphanet61 C1333984
ICD1025 C86.1

Related Diseases for Hepatosplenic T-Cell Lymphoma

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Hepatosplenic T-Cell Lymphoma:



Diseases related to hepatosplenic t-cell lymphoma

Clinical Features for Hepatosplenic T-Cell Lymphoma

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Drugs & Therapeutics for Hepatosplenic T-Cell Lymphoma

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Hepatosplenic T-Cell Lymphoma

Drug clinical trials:

Search ClinicalTrials for Hepatosplenic T-Cell Lymphoma

Search NIH Clinical Center for Hepatosplenic T-Cell Lymphoma

Search CenterWatch for Hepatosplenic T-Cell Lymphoma

Genetic Tests for Hepatosplenic T-Cell Lymphoma

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Anatomical Context for Hepatosplenic T-Cell Lymphoma

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Sources:
32MalaCards
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MalaCards organs/tissues related to Hepatosplenic T-Cell Lymphoma:

32
T cells

Animal Models for Hepatosplenic T-Cell Lymphoma or affiliated genes

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Publications for Hepatosplenic T-Cell Lymphoma

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Genetic Variations for Hepatosplenic T-Cell Lymphoma

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Expression for genes affiliated with Hepatosplenic T-Cell Lymphoma

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hepatosplenic T-Cell Lymphoma

Search GEO for disease gene expression data for Hepatosplenic T-Cell Lymphoma.

Pathways for genes affiliated with Hepatosplenic T-Cell Lymphoma

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Sources:
29KEGG
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Pathways related to Hepatosplenic T-Cell Lymphoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1CD7, TNF

Compounds for genes affiliated with Hepatosplenic T-Cell Lymphoma

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Sources:
44Novoseek, 49PharmGKB, 28IUPHAR, 11DrugBank, 24HMDB
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Compounds related to Hepatosplenic T-Cell Lymphoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1atorvastatin44 49 28 11 2413.1TNF, DPP4
2rosiglitazone44 49 28 11 2413.0DPP4, TNF
3butyrate449.0DPP4, TNF
4methotrexate44 49 1110.9TNF, DPP4
5rantes448.7DPP4, TNF

GO Terms for genes affiliated with Hepatosplenic T-Cell Lymphoma

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Sources:
16Gene Ontology
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Cellular components related to Hepatosplenic T-Cell Lymphoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1membrane raftGO:0451219.0DPP4, TNF

Biological processes related to Hepatosplenic T-Cell Lymphoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to hypoxiaGO:0016669.0DPP4, TNF
2T cell activationGO:0421109.0CD7, DPP4

Molecular functions related to Hepatosplenic T-Cell Lymphoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protease bindingGO:0020209.0DPP4, TNF

Products for genes affiliated with Hepatosplenic T-Cell Lymphoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Hepatosplenic T-Cell Lymphoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet