MCID: HPT070
MIFTS: 26

Hepatosplenic T-Cell Lymphoma malady

Cancer diseases, Blood diseases, Rare diseases, Immune diseases, Liver diseases categories
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Summaries for Hepatosplenic T-Cell Lymphoma

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33MalaCards
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MalaCards: Hepatosplenic T-Cell Lymphoma is related to t-cell leukemia and crohn's disease. An important gene associated with Hepatosplenic T-Cell Lymphoma is DPP4 (dipeptidyl-peptidase 4). Affiliated tissues include t cells, skin and nk cells.

Aliases & Classifications for Hepatosplenic T-Cell Lymphoma

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49Orphanet, 62UMLS, 26ICD10 via Orphanet, 59SNOMED-CT via Orphanet, 63UMLS via Orphanet, 25ICD10
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Classifications:



Characteristics (Orphanet epidemiological data):

49
hepatosplenic t-cell lymphoma:
Age of onset: Adolescence / Young adulthood


Aliases & Descriptions:

hepatosplenic t-cell lymphoma 49 62


External Ids:

ICD10 via Orphanet26 C84.4
SNOMED-CT via Orphanet59 445406001
UMLS via Orphanet63 C1333984
ICD1025 C86.1

Related Diseases for Hepatosplenic T-Cell Lymphoma

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Hepatosplenic T-Cell Lymphoma:



Diseases related to hepatosplenic t-cell lymphoma

Symptoms for Hepatosplenic T-Cell Lymphoma

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Drugs & Therapeutics for Hepatosplenic T-Cell Lymphoma

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Hepatosplenic T-Cell Lymphoma

Search NIH Clinical Center for Hepatosplenic T-Cell Lymphoma

Genetic Tests for Hepatosplenic T-Cell Lymphoma

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Anatomical Context for Hepatosplenic T-Cell Lymphoma

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33MalaCards
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MalaCards organs/tissues related to Hepatosplenic T-Cell Lymphoma:

33
T cells, Skin, Nk cells

Animal Models for Hepatosplenic T-Cell Lymphoma or affiliated genes

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Publications for Hepatosplenic T-Cell Lymphoma

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52PubMed
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Articles related to Hepatosplenic T-Cell Lymphoma:

(show top 50)    (show all 65)
idTitleAuthorsYear
1
Hepatosplenic T-cell lymphoma appearing in the peripheral blood. (24137640)
2013
2
Successful treatment of hepatosplenic T-cell lymphoma with ESHAP followed by autologous stem cell transplant. (23598914)
2013
3
Hepatosplenic T-cell lymphoma: is cure possible? (23598915)
2013
4
Hepatosplenic T-cell lymphoma. (24033076)
2013
5
Use of case reports and the Adverse Event Reporting System in systematic reviews: overcoming barriers to assess the link between Crohn's disease medications and hepatosplenic T-cell lymphoma. (23826928)
2013
6
Intensive induction chemotherapy followed by early high-dose therapy and hematopoietic stem cell transplantation results in improved outcome for patients with hepatosplenic T-cell lymphoma: a single institution experience. (23107915)
2013
7
The incidence of hepatosplenic T-cell lymphoma in a large managed care organization, with reference to anti-tumor necrosis factor therapy, Northern California, 2000-2006. (21823196)
2012
8
Hematologic features of hepatosplenic T-cell lymphoma. (22261460)
2012
9
F-18 Fluorodeoxyglucose non-avid hepatosplenic T cell lymphoma: a diagnostic pitfall. (21584668)
2012
10
Molecular features of hepatosplenic T-cell lymphoma unravels potential novel therapeutic targets. (22510872)
2012
11
Clinicopathological features of hepatosplenic T cell lymphoma: a single centre experience from India. (21916832)
2012
12
Differential diagnosis of CD4-/CD8- I^I' T-cell large granular lymphocytic leukemia and hepatosplenic T-cell lymphoma. (22338065)
2012
13
Hepatosplenic T-cell lymphoma is a distinct rare entity: diagnosis by fine-needle aspiration cytology. (21837655)
2011
14
Cytogenetic and molecular characterization of a hepatosplenic T-cell lymphoma: report of a novel chromosomal aberration. (21504708)
2011
15
Hepatosplenic T-cell lymphoma in patients receiving TNF-I+ inhibitor therapy: expanding the groups at risk. (21941193)
2011
16
A systematic review of factors that contribute to hepatosplenic T-cell lymphoma in patients with inflammatory bowel disease. (20888436)
2011
17
Common variable immunodeficiency associated with hepatosplenic T-cell lymphoma mimicking juvenile systemic lupus erythematosus. (21776287)
2011
18
Hepatosplenic T cell lymphoma responsive to 2'-deoxycoformycin therapy. (20652973)
2010
19
A seventeen-year-old female with hepatosplenic T-cell lymphoma associated with parvoviral infection. (21589836)
2010
20
Hepatosplenic T-cell lymphoma in a young man with Crohn's disease: case report and literature review. (20371449)
2010
21
Hepatosplenic T-cell lymphoma and inflammatory bowel disease. (21122554)
2010
22
Crohn's disease, hepatosplenic T-cell lymphoma and no biological therapy: are we barking up the wrong tree? (19067412)
2009
23
Sustained first remission in an adolescent with hepatosplenic T-cell lymphoma treated with T-cell leukemia induction, nucleoside analog-based consolidation, and early hematopoietic stem cell transplant. (19479793)
2009
24
Importance of early splenectomy in patients with hepatosplenic T-cell lymphoma and severe thrombocytopenia. (19408055)
2009
25
Hepatosplenic T-cell lymphoma following infliximab therapy for Crohn's disease. (19296822)
2009
26
Hepatosplenic T cell lymphoma associated with infliximab use in young patients treated for inflammatory bowel disease: update. (19274799)
2009
27
Hepatosplenic T cell lymphoma in inflammatory bowel disease. (18667489)
2008
28
Post-transplant hepatosplenic T-cell lymphoma successfully treated with HyperCVAD regimen. (17876769)
2008
29
Hepatosplenic T-cell lymphoma following infliximab therapy for Crohn's disease. (18928444)
2008
30
Long-term survival in two patients with hepatosplenic T cell lymphoma treated with interferon-alpha. (18452073)
2008
31
Hepatosplenic T cell lymphoma associated with infliximab use in young patients treated for inflammatory bowel disease. (17255842)
2007
32
Infliximab use and hepatosplenic T cell lymphoma: questions to be asked and lessons learned. (17255825)
2007
33
Gamma-delta hepatosplenic T-cell lymphoma. Description of a case with immunophenotypic and molecular follow-up successfully treated with chemotherapy alone. (16321867)
2006
34
Ring chromosome 7 with amplification of 7q sequences in a pediatric case of hepatosplenic T-cell lymphoma. (16737917)
2006
35
Progressive multifocal leukoencephalopathy in a patient with hepatosplenic T cell lymphoma. (16479120)
2006
36
NK-cell-associated receptor expression in hepatosplenic T-cell lymphoma, insights into pathogenesis. (16525496)
2006
37
Hepatosplenic T-cell lymphoma in an adolescent patient after immunomodulator and biologic therapy for Crohn disease. (15699701)
2005
38
Case report: a common presentation of a rare disease-hepatosplenic T-cell lymphoma. (15633661)
2004
39
Morphologic, immunohistochemical, and molecular characterization of hepatosplenic T-cell lymphoma in a dog. (15195270)
2004
40
Hematologic malignancies with extramedullary spread of disease. Case 2. Hepatosplenic T-cell lymphoma. (12721269)
2003
41
Hepatosplenic T cell lymphoma with no expression of cytotoxic molecules. (12890821)
2003
42
Hepatosplenic T-cell lymphoma in a mare. (12126157)
2002
43
Hepatosplenic T-cell lymphoma. (11472337)
2001
44
Hepatosplenic alphabeta T-cell lymphoma: an unusual case with clinical, histologic, and cytogenetic features of gammadelta hepatosplenic T-cell lymphoma. (10895827)
2000
45
Hepatosplenic T-cell lymphoma of alphabeta lineage in a 16-year-old boy presenting with hemolytic anemia and thrombocytopenia. (10716161)
2000
46
Hepatosplenic T cell lymphoma. A review on 45 cases since the first report describing the disease as a distinct lymphoma entity in 1990. (10865963)
2000
47
Cytotoxic T-lymphocyte differentiation and cytogenetic alterations in gammadelta hepatosplenic T-cell lymphoma and posttransplant lymphoproliferative disorders. (9129060)
1997
48
Hepatosplenic T-cell lymphoma: sinusoidal localization of malignant T-cells--a case report. (8948673)
1996
49
Hepatosplenic T-cell lymphoma: a distinct clinicopathologic entity of cytotoxic gamma delta T-cell origin. (8943863)
1996
50
Hepatosplenic T-cell lymphoma: an unusual case of a gamma delta T-cell lymphoma with a blast-like terminal transformation. (8314255)
1994

Variations for Hepatosplenic T-Cell Lymphoma

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Expression for genes affiliated with Hepatosplenic T-Cell Lymphoma

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hepatosplenic T-Cell Lymphoma

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Pathways for genes affiliated with Hepatosplenic T-Cell Lymphoma

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Compounds for genes affiliated with Hepatosplenic T-Cell Lymphoma

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GO Terms for genes affiliated with Hepatosplenic T-Cell Lymphoma

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16Gene Ontology
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Biological processes related to Hepatosplenic T-Cell Lymphoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1T cell activationGO:0421109.1CD7, DPP4

Products for genes affiliated with Hepatosplenic T-Cell Lymphoma

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Sources for Hepatosplenic T-Cell Lymphoma

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet