MCID: HRD084
MIFTS: 27

Hereditary Cerebral Amyloid Angiopathy malady

Categories: Genetic diseases, Rare diseases, Cardiovascular diseases, Neuronal diseases, Bone diseases, Metabolic diseases

Aliases & Classifications for Hereditary Cerebral Amyloid Angiopathy

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Aliases & Descriptions for Hereditary Cerebral Amyloid Angiopathy:

Name: Hereditary Cerebral Amyloid Angiopathy 23 47
Autosomal Dominant Cerebrovascular Amyloidosis 23
Cerebral Amyloid Angiopathy, Hereditary 65
Cerebral Amyloid Angiopathy, Familial 23
Cerebral Amyloid Angiopathy, Genetic 23
 
Cerebral Amyloid Angiopathy Familial 47
Familial Cerebral Amyloid Angiopathy 65
Hchwa 23
Caa 23

Classifications:



External Ids:

UMLS65 C1510489, C0268393

Summaries for Hereditary Cerebral Amyloid Angiopathy

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Genetics Home Reference:23 Hereditary cerebral amyloid angiopathy is a condition that can cause a progressive loss of intellectual function (dementia), stroke, and other neurological problems starting in mid-adulthood. Due to neurological decline, this condition is typically fatal in one's sixties, although there is variation depending on the severity of the signs and symptoms. Most affected individuals die within a decade after signs and symptoms first appear, although some people with the disease have survived longer.

MalaCards based summary: Hereditary Cerebral Amyloid Angiopathy, also known as autosomal dominant cerebrovascular amyloidosis, is related to cerebral amyloid angiopathy and cerebral amyloid angiopathy, dutch, italian, iowa, flemish, arctic variants. An important gene associated with Hereditary Cerebral Amyloid Angiopathy is TUBB (Tubulin Beta Class I), and among its related pathways are A-beta Pathways: Plaque Formation and APP Metabolism and Integrated Pancreatic Cancer Pathway. Affiliated tissues include bone, thyroid and prostate.

Related Diseases for Hereditary Cerebral Amyloid Angiopathy

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Diseases in the Cerebral Amyloid Angiopathy family:

hereditary cerebral amyloid angiopathy

Diseases related to Hereditary Cerebral Amyloid Angiopathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 14)
idRelated DiseaseScoreTop Affiliating Genes
1cerebral amyloid angiopathy11.8
2cerebral amyloid angiopathy, dutch, italian, iowa, flemish, arctic variants11.3
3cerebritis10.5
4cerebral hemorrhage10.2
5dementia10.0
6amyloidosis10.0
7dementia, familial danish9.9APP, TUBB
8cerebral palsy9.6APP, CST3
9retinal arteries, tortuosity of9.6APP, CST3
10macular degeneration, age-related, 119.5APP, CST3
11jervell and lange-nielsen syndrome 29.5APP, CST3
12milker's nodule9.4APP, CST3
13eczema herpeticum9.3APP, CST3
14hereditary hypophosphatemic rickets9.1APP, CST3, TUBB

Graphical network of diseases related to Hereditary Cerebral Amyloid Angiopathy:



Diseases related to hereditary cerebral amyloid angiopathy

Symptoms for Hereditary Cerebral Amyloid Angiopathy

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Drugs & Therapeutics for Hereditary Cerebral Amyloid Angiopathy

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Hereditary Cerebral Amyloid Angiopathy

Genetic Tests for Hereditary Cerebral Amyloid Angiopathy

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Anatomical Context for Hereditary Cerebral Amyloid Angiopathy

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MalaCards organs/tissues related to Hereditary Cerebral Amyloid Angiopathy:

33
Bone, Thyroid, Prostate

Animal Models for Hereditary Cerebral Amyloid Angiopathy or affiliated genes

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MGI Mouse Phenotypes related to Hereditary Cerebral Amyloid Angiopathy:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes

Publications for Hereditary Cerebral Amyloid Angiopathy

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Articles related to Hereditary Cerebral Amyloid Angiopathy:

idTitleAuthorsYear
1
Iowa APP mutation-related hereditary cerebral amyloid angiopathy (CAA): A new family from Spain. (27000221)
2016
2
Iowa-type hereditary cerebral amyloid angiopathy in a Polish family. (26104569)
2015
3
Vascular changes in Iowa-type hereditary cerebral amyloid angiopathy. (12480757)
2002
4
From gene to disease; amyloid-beta precursor protein gene instrumental in hereditary cerebral amyloid angiopathies]. (11552366)
2001
5
Dutch hereditary cerebral amyloid angiopathy: structural lesions and apolipoprotein E genotype. (9153536)
1997
6
No protective effect of apolipoprotein E epsilon 2 allele in Dutch hereditary cerebral amyloid angiopathy. (7847872)
1995
7
Progressive dementia, without cerebral hemorrhage, in a patient with hereditary cerebral amyloid angiopathy. (1335860)
1992
8
Comparison between the Icelandic and Dutch forms of hereditary cerebral amyloid angiopathy. (1320529)
1992
9
Hereditary cerebral hemorrhage with amyloidosis--Dutch type. Research-Group Hereditary Cerebral Amyloid-Angiopathy. (2555088)
1989
10
Hereditary cerebral amyloid angiopathy: the amyloid fibrils contain a protein which is a variant of cystatin C, an inhibitor of lysosomal cysteine proteases. (3707586)
1986

Variations for Hereditary Cerebral Amyloid Angiopathy

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Expression for genes affiliated with Hereditary Cerebral Amyloid Angiopathy

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Search GEO for disease gene expression data for Hereditary Cerebral Amyloid Angiopathy.

Pathways for genes affiliated with Hereditary Cerebral Amyloid Angiopathy

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GO Terms for genes affiliated with Hereditary Cerebral Amyloid Angiopathy

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Sources for Hereditary Cerebral Amyloid Angiopathy

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet