Summaries for Herpes Zoster

Sources:
6Disease Ontology, 23MedlinePlus, 2CDC, 31NINDS, 44Wikipedia, 22MalaCards
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Export this MalaCard
MedlinePlus: Shingles is a disease caused by the varicella-zoster virus - the same virus that causes chickenpox. after you have chickenpox, the virus stays in your body. it may not cause problems for many years. as you get older, the virus may reappear as shingles. unlike chickenpox, you can't catch shingles from someone who has it. early signs of shingles include burning or shooting pain and tingling or itching, usually on one side of the body or face. the pain can be mild to severe. blisters then form and last from one to 14 days. if shingles appears on your face, it may affect your vision or hearing. the pain of shingles may last for weeks, months or even years after the blisters have healed. there is no cure for shingles. early treatment with medicines that fight the virus may help. these medicines may also help prevent lingering pain. a vaccine may prevent shingles or lessen its effects. the vaccine is for people 60 or over. nih: national institute of allergy and infectious diseases23

MalaCards: Herpes Zoster, also known as shingles, is related to geniculate herpes zoster and postherpetic neuralgia, and has symptoms including rash which is followed by blisters, headache and fever. An important gene associated with Herpes Zoster is FCGR3A (Fc fragment of IgG, low affinity IIIa, receptor (CD16a)), and among its related pathways are Immune response_CD16 signaling in NK cells and Primary immunodeficiency. The drugs capsacian pwdr [va product] and capsaicin and the compounds ivig and pge2 have been mentioned in the context of this disorder. Affiliated tissues include nerve fiber, skin and t cells, and related mouse phenotypes are hematopoietic system and liver/biliary system.

Disease Ontology: A viral infectious disease that results in infection located in nerve fiber, has material basis in human herpesvirus 3, which reactivates after appearing as chickenpox in childhood. the virus is transmitted by direct contact with the rash, which can develop into chickenpox in newly-infected individuals. the infection has symptom rash which is followed by blisters, has symptom headache, has symptom fever, has symptom malaise, has symptom itching, has symptom burning pain, and has symptom paresthesia.6

CDC: Shingles, also known as zoster or herpes zoster, is a painful skin rash caused by the varicella zoster virus, the same virus that causes chickenpox. Nearly 1 out of every 3 people in the United States will develop shingles. Anyone who has recovered from chickenpox may develop shingles; even children can get shingles. However, the risk of getting the disease increases as a person gets older. About half of all cases occur among men and women who are 60 years old or older... more2

NINDS: Shingles (herpes zoster) is an outbreak of rash or blisters on the skin that is caused by the same virus that causes chickenpox ? the varicella-zoster virus. The first sign of shingles is often burning or tingling pain, or sometimes numbness or itch, in one particular location on only one side of the body. After several days or a week, a rash of fluid-filled blisters, similar to chickenpox, appears in one area on one side of the body. Shingles pain can be mild or intense. 31

Wikipedia: Herpes zoster (or simply zoster), commonly known as shingles and also known as zona, is a viral disease...44 more...

Aliases & Descriptions for Herpes Zoster

Sources:
2CDC, 6Disease Ontology, 31NINDS, 8DISEASES, 32Novoseek , 23MedlinePlus, 43UMLS, 19ICD9CM, 40SNOMED-CT, 24MeSH, 27NCIt
See all sources

Aliases & Descriptions:

herpes zoster 6 31 8 32
shingles 6 31 23
herpes zoster disease 43
herpes zona 6

External Ids:

ICD9CM19 053
SNOMED-CT40 186514003, 154326002, 4740000 186533008, more

Related Diseases for Herpes Zoster

Sources:
13GeneCards, 14GeneDecks
See all sources

Diseases related to herpes zoster by text searches and GeneDecks gene sharing:

(show top 50)    (show all 587)
idRelated DiseaseScoreTop Affiliating Genes
1geniculate herpes zoster35.6GPHN, TUBA1A, NIN
2postherpetic neuralgia32.3HLA-A, HLA-B, HLA-DRB1
3chickenpox29.1GYPC, TKT, DPYD
4multiple sclerosis27.8APOE, CCR5, IFNG, HLA-A, HLA-B, HLA-DRB1
5systemic lupus erythematosus27.4CD79A, CD4, FCGR3A, IL10, IL4, CCR5
6systemic lupus erythematosus, association with26.8FCGR3A, IL10, IL4, IFNA2, IFNG, HP
7lupus erythematosus23.8MS4A1, CD79A, CD8A, CD4, FCGR3A, IL10
8anemia22.3CD79A, CD4, CD9, IL10, IL4, CCR5
9rheumatoid arthritis21.2MS4A1, CD79A, CD4, CD9, GYPC, FCGR3A
10arthritis20.7MS4A1, CD79A, CD8A, CD4, CD9, GYPC
11necrobiotic xanthogranuloma13.5CD79A, IFNA2
12granulomatous hepatitis13.4IFNA1, IFNA2
13dysentery13.4CD79A, IFNA2, TMPO
14lymphomatoid granulomatosis13.4IFNA1, IFNA2
15membranous glomerulonephritis13.3CD79A, CCR5, HP
16focal epithelial hyperplasia13.3IFNA2, HLA-DRB1
17alpers syndrome13.2REV3L, POLA1, POLD1, POLE
18reactive arthritis13.2CD79A, HP, HLA-B
19sm-ahnmd13.2MS4A1, IFNA1, IFNA2, TKT
20chronic progressive external ophthalmoplegia13.2REV3L, POLA1, POLD1, POLE
21skin tag13.2REV3L, POLA1, POLD1, POLE
22cold agglutinin disease13.2MS4A1, HP, TNF
23autoimmune thrombocytopenic purpura13.2CD79A, IFNA1, IFNA2
24mastocytosis13.2MS4A1, IFNA1, IFNA2, TKT
25membranoproliferative glomerulonephritis type 213.1CD79A, IFNA1, IFNA2
26coccidiosis13.1CD8A, CD4, IFNG
27cutaneous leishmaniasis13.1IL10, IFNG
28punctate inner choroidopathy13.1IL10, TNF
29buruli ulcer disease13.0IL10, IFNG
30htlv-1 associated myelopathy13.0IFNA1, HLA-A, HLA-B
31tuberculoid leprosy13.0IL10, IFNG
32xeroderma pigmentosum13.0REV3L, CD8A, POLA1, POLD1, POLE
33pars planitis13.0HLA-A, HLA-B, HLA-DRB1
34lymphoproliferative syndrome13.0MS4A1, CD4, CCR5, HLA-A
35adult glioblastoma multiforme13.0HLA-A, HLA-B, HLA-DRB1
36progressive multifocal leukoencephalopathy13.0CD4, CD9, TNF
37nasopharynx carcinoma12.9CD79A, HLA-A, HLA-B, TKT
38chronic inflammatory demyelinating polyneuropathy12.9IFNA1, IFNA2, TNF
39tuberculous uveitis12.9IFNG, TNF
40hiv-1, resistance to12.9CD4, IL10, CCR5, HLA-A
41lymphocytic colitis12.9CD79A, NOS2
42meningoencephalitis12.9CD79A, CD4, TNF
43hepatitis d12.9IGHV4-39, IFNA1, IFNA2, TNF
44coccidioidomycosis12.9CD4, IL10, IFNG
45proliferative glomerulonephritis12.9CD79A, CCR5, IFNG
46relapsing polychondritis12.8CD79A, IL10, IFNG
47primary immunodeficiency disease12.8CD8A, CD4, FCGR3A, IL4, IGHV4-39
48hepatitis e12.8IGHV4-39, IFNA1, IFNA2, IFNG
49pityriasis rosea12.8IFNA2, HLA-A, HLA-B, HLA-DRB1
50diffuse panbronchiolitis12.8CD79A, HLA-A, TNF

Graphical network of the top 20 diseases related to herpes zoster:



Graphical network of diseases related to herpes zoster

Clinical Features for Herpes Zoster

Sources:
6Disease Ontology
See all sources
Symptoms: rash which is followed by blisters, headache, fever, malaise, itching, burning pain, paresthesia.6

Drugs & Therapeutics for Herpes Zoster

Sources:
4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials, 43UMLS, 28NDF-RT
See all sources

Approved drugs:

Search CenterWatch for herpes zoster

Drug clinical trials:

Search ClinicalTrials for herpes zoster

Search NIH Clinical Center for herpes zoster

Search CenterWatch for herpes zoster

Inferred drug relations via UMLS/NDF-RT:

43 28 capsacian pwdr [va product], capsaicin, capsaicin pwdr [va product], capsicum, capsicum oleoresin, valacyclovir, valacyclovir hydrochloride

Genetic Tests for Herpes Zoster

Anatomical Context for Herpes Zoster

Sources:
11FMA, 22MalaCards
See all sources

MalaCards organs/tissues related to herpes zoster:

22
Skin, T cells

FMA organs/tissues related to herpes zoster:

11
Nerve fiber

Phenotypes for genes affiliated with Herpes Zoster

Sources:
25MGI
See all sources

MGI Mouse Phenotypes related to herpes zoster:

25 (show all 12)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1hematopoietic system phenotypeMP:00053979.8REV3L, CD8A, TMPO, POLD1, POLE
2liver/biliary system phenotypeMP:00053709.7CCR5, IFNG
3respiratory system phenotypeMP:00053889.7GPHN, APOE
4endocrine/exocrine gland phenotypeMP:00053799.3TKT, TMPO, IFNG, SATB2
5integument phenotypeMP:00107718.6POLE, POLD1, TMPO, IFNG, IL4, CD4
6immune system phenotypeMP:00053878.4POLE, POLD1, TNF, IFNG, CD9, CD4
7digestive/alimentary phenotypeMP:00053818.2NOS2, TMPO, IFNG, CCR5, APOE, CD4
8tumorigenesisMP:00020067.7POLE, POLD1, NOS2, TNF, HP, IFNG
9no phenotypic analysisMP:00030127.4TNF, IFNG, CCR5, APOE, IL4, IL10
10vision/eye phenotypeMP:00053916.8TKT, NOS2, TNF, IFNG, GPHN, CCR5
11mortality/agingMP:00107685.5POLD1, TKT, NOS2, TNF, HP, IFNG
12cellular phenotypeMP:00053845.5IFNG, HP, TUBA1A, TNF, TMPO, NOS2

Publications for genes affiliated with Herpes Zoster

Sources:
35PubMed
See all sources

Articles related to herpes zoster:

(show all 20)
idTitleAuthorsYearAffiliating Genes
1Alteration in antibody-mediated immunity in patients with rituximab-combined chemotherapy and incidence of herpes zoster (20087040)Ito K.... Emi N.2010MS4A1
2Risk of herpes zoster in patients with rheumatoid arthritis treated with anti-TNF-alpha agents. (19224750)Strangfeld A.... Zink A.2009TNF
3Herpes zoster in patients taking TNFalpha antagonists for chronic inflammatory joint disease. (18674945)Wendling D.... Prati C.2008TNF
4Polymorphism of the IL-10 gene is associated with susceptibility to herpes zoster in Korea. (17204399)Cho J.W.... Lee K.S.2007IL10
5Localized linear IgA dermatosis induced by UV light-t reatment for herpes zoster. (17472682)He C.... Chen H.D.2007CD79A
6Impact of CCR5 Delta32/+ deletion on herpes zoster among HIV-1-infected homosexual men. (16703416)Krol A.... Coutinho R.A.2006CCR5
7Clinical and genetic risk factors of herpes zoster in patients with systemic lupus erythematosus. (14593495)Kang T.Y.... Yoo D.H.2005FCGR3A
8Association of reduced CD4 T cell responses specific to varicella zoster virus with high incidence of herpes zoster in patients with systemic lupus erythematosus. (15517626)Park H.B.... Jung S.2004IL4, IFNG, IL10
9The human histocompatibility leukocyte antigen (HLA) haplotype is associated with the onset of postherpetic neuralgia after herpes zoster. (15275783)Sato-Takeda M.... Yabe T.2004HLA-A, HLA-DRB1, HLA-B
10Discovery and development of BVDU (brivudin) as a therapeutic for the treatment of herpes zoster. (15548377)De Clercq E.2004DPYD
11Polymorphism of the IL-10 gene is associated with susceptibility to herpes zoster. (11928840)Haanpaa M.... Hurme M.2002IL10
12Expression of inducible nitric oxide synthase in skin lesions of acute herpes zoster. (12234710)Lim Y.J.... Lee D.S.2002NOS2
13Apolipoprotein E (APOE) phenotype and APOE concentrations in multiple sclerosis and acute herpes zoster. (10949525)Pirttila T.... Lehtimaki T.2000APOE
14Comparative study of transfer factor and acyclovir in the treatment of herpes zoster. (9839657)Estrada-Parra S.... Estrada-Garcia I.1998IFNG, IFNA1
15Clinical trial of recombinant alpha-2a interferon in the treatment of herpes zoster (11367689)Liu Y.... Li S.1998IFNA2
16The effect of sorivudine on dihydropyrimidine dehydrogenase activity in patients with acute herpes zoster. (9164418)Yan J.... Diasio R.B.1997DPYD
17Treatment of herpes zoster: recombinant alpha-2a-inte rferon versus acyclovir and vitamin therapy. Clinical Study Group on Interferon . (8274720)Yu B.1993IFNA2, IFNA1
18T-lymphocyte subsets in otherwise healthy patients with herpes zoster and relationships to the duration of acute herpetic pain. (1454393)Higa K.... Dan K.1992CD8A
19An elderly case of systemic lupus erythematosus associated with herpes zoster, anemia, and hemiparesis (1795445)Hashizume K.... Onishi T.1991HP
20Therapeutic indications in herpes zoster (1828198)CarcA^ F.... Guazzotti G.1991TMPO

Expression for genes affiliated with Herpes Zoster

Sources:
1BioGPS
See all sources
Expression patterns in normal tissues for genes affiliated with Herpes Zoster

Pathways for genes affiliated with Herpes Zoster

Sources:
41Thomson Reuters, 20KEGG, 36QIAGEN, 38Reactome, 10EMD Millipore, 37R&D Systems
See all sources

Pathways related to herpes zoster according to GeneDecks:

(show all 39)
idPathwayScoreTop Affiliating Genes
1Immune response_CD16 signaling in NK cells4110.5FCGR3A
2Primary immunodeficiency2010.4CD4
3Cell adhesion molecules (CAMs)2010.4CD8A, CD4
4Graft-versus-host disease2010.3HLA-A, HLA-B
5OX40 Pathway3610.3IL4
6Amoebiasis2010.1NOS2
7Pyrimidine metabolism209.9POLE, POLD1, POLA1, DPYD
8Immune System389.9CD79A, FCGR3A, IFNG
9Cell cycle Transition and termination of DNA replacation109.8POLE, POLD1, POLA1
10DNA replication209.7POLA1, POLD1, POLE
11Antigen processing and presentation209.6CD8A, CD4, HLA-DRB1
12Cell cycle_Transition and termination of DNA replication419.5POLD1, POLA1, POLE
13Malaria209.5TNF, IFNG, IL10, GYPC
14Th1 Differentiation379.3CD4, IL10, IFNG, TNF
15African trypanosomiasis209.3TNF, IFNG, IL10
16CTL Mediated Apoptosis369.2HLA-DRB1, HLA-B, HLA-A
17Immune response_MIF-mediated glucocorticoid regulation419.2NOS2, TNF, IFNG
18Phagosome209.2TUBA1A, HLA-DRB1, HLA-B, HLA-A, FCGR3A
19Immune response MIF-mediated glucocorticoid regulation109.2NOS2, TNF, IFNG
20Immune response CD16 signaling in NK cells109.0FCGR3A, IL4, IFNG, TNF
21Jak-STAT signaling pathway209.0IL10, IL4, IFNA1, IFNA2, IFNG
22Chagas disease (American trypanosomiasis)208.9NOS2, TNF, IFNG, IL10
23STAT3 Pathway368.9CD4, IL10, IL4, CCR5, TNF
24Asthma208.8TNF, HLA-DRB1, IL4, IL10
25Natural killer cell mediated cytotoxicity208.7TNF, HLA-B, HLA-A, IFNG, IFNA2, IFNA1
26Systemic lupus erythematosus208.7TNF, HLA-DRB1, IFNG, IL10, FCGR3A
27T cell receptor signaling pathway208.6TNF, IFNG, IL4, IL10, CD4, CD8A
28JAK-STAT Pathway368.6IFNG, IFNA2, IFNA1, IL4, IL10, CD4
29Cytokine Network368.6TNF, IFNG, IFNA2, IFNA1, IL4, IL10
30Type I diabetes mellitus208.5TNF, HLA-DRB1, HLA-B, HLA-A, IFNG
31Influenza A208.4TNF, HLA-DRB1, IFNG, IFNA2, IFNA1
32Hematopoietic cell lineage208.3TNF, HLA-DRB1, IL4, CD9, CD4, CD8A
33THC Differentiation Pathway368.3TNF, HLA-DRB1, IFNG, IL4, IL10
34Cytokine-cytokine receptor interaction208.2TNF, IFNG, IFNA2, IFNA1, CCR5, IL4
35Autoimmune thyroid disease208.2HLA-DRB1, HLA-B, HLA-A, IFNA2, IFNA1, IL4
36Toxoplasmosis207.9NOS2, TNF, HLA-DRB1, IFNG, CCR5, IL10
37Allograft rejection207.8IL10, TNF, HLA-DRB1, HLA-B, HLA-A, IFNG
38Leishmaniasis207.6NOS2, TNF, HLA-DRB1, IFNG, IL4, IL10
39Tuberculosis207.6NOS2, TNF, HLA-DRB1, IFNG, IFNA2, IFNA1

Compounds for genes affiliated with Herpes Zoster

Sources:
32Novoseek , 34PharmGKB, 9DrugBank, 18HMDB, 42Tocris Bioscience
See all sources

Compounds related to herpes zoster according to GeneDecks:

(show top 50)    (show all 130)
idCompoundScoreTop Affiliating Genes
1ivig32 10.5FCGR3A, CCR5
2pge232 10.3TMPO, HP, CD4
3rituximab32 34 9 9 13.2IL10, FCGR3A, MS4A1, CD79A
4vegf32 10.0DPYD, TKT, HP, APOE
55-deoxy-5-fluorouridine32 10.0TKT, IFNA2, IFNA1, DPYD
6polyethylene glycol32 10.0APOE, HP, IFNA2, CD9
7okt332 9.9CD79A, IL10, TNF
8leucovorin32 34 9 9 12.8IFNA1, DPYD, TKT, TMPO, IFNA2
9didanosine32 9 9 11.8TKT, CD4, CD9, IFNA1, IFNA2
10acyclovir32 9.6IFNA1, CD9, IFNA2, IFNG, TKT
11tuberculin32 9.5CD79A, IL10, IFNG, HP
12nucleoside32 9.3CCR5, DPYD, IFNA1, IFNA2, TKT, HP
13adalimumab32 9 9 11.3CD79A, FCGR3A, IL10, IFNG, TNF
14betaseron32 9.2IFNG, IFNA1, IL4, IL10
15ursodeoxycholic acid32 9 18 9 12.2HLA-B, APOE, IFNA1, IFNA2, HLA-A
16etanercept32 9 9 11.2FCGR3A, TNF, IFNG, IFNA2, IL10
17natalizumab32 9 9 11.2FCGR3A, IFNG, TNF, IL10
18mdms32 9.2CCR5, CD4, CD9, IL10
19mip 1alpha32 9.2TNF, CCR5, IL10, IL4
20zidovudine32 9 9 11.1TKT, TMPO, IFNA2, CCR5, IL10, CD9
21interferon gamma32 9.1IL10, IL4, IFNG, TNF
22imiquimod32 42 9 9 12.1TNF, IFNG, IFNA2, IFNA1, IL10
23con a32 9.0IFNG, IFNA2, IL4, IL10, CD79A, HP
24rolipram32 42 10.0CD9, IL10, IL4, IFNG, TNF
252,5-oligoadenylate32 8.9IL10, IFNG, TNF, HLA-B, IFNA2, IFNA1
26pentoxifylline32 9 9 10.8TNF, HP, IFNG, IL4, IL10, CD9
27il-1232 8.8IL10, IFNA1, TNF, IL4, IFNG
285fluorouracil32 8.8TMPO, TKT, DPYD, IFNA2, HLA-A, IFNG
29infliximab32 9 9 10.6IFNA2, IL4, TNF, IFNG, IL10
30il 1032 8.6TNF, CCR5, IL4, IL10, IFNG, CD8A
31ribavirin32 34 9 9 11.6IFNA2, CCR5, IFNA1, HP, IL10, IFNG
32paraffin32 8.6HLA-B, TKT, DPYD, CD9, APOE, IL4
33melphalan32 9 9 10.5CD79A, TNF, IFNA2, IFNA1, IL4, IFNG
34tarc32 8.5CCR5, IFNG, TNF, IL4, IL10, CD4
35rantes32 8.5CCR5, IL4, CD9, IFNA1, HLA-B, IFNG
36methotrexate32 34 42 9 9 12.5DPYD, IL10, CD79A, FCGR3A, HLA-DRB1, TKT
37glatiramer acetate32 9 9 10.4IL4, IL10, IFNA1, IFNG, HLA-DRB1
38prednisolone32 9 9 10.4IFNG, TNF, IL10, IFNA1, IFNA2, CD79A
39chloroquine32 34 9 9 11.2CD79A, CD4, IL10, IL4, APOE, IFNA1
40arginine32 8.2HLA-DRB1, HLA-A, HLA-B, CD79A, FCGR3A, TMPO
41herbimycin a32 42 9.2TKT, TNF, IFNG, FCGR3A, CD4, NOS2
42thymidine32 18 9.0GYPC, CD9, TKT, DPYD, IL4, IFNA1
43tacrolimus32 34 9 9 11.0TNF, CD79A, IL10, IL4, IFNA1, IFNG
44polyinosinic-polycytidylic acid32 7.9IFNA1, IL10, IL4, IFNG, HLA-B, TNF
45neopterin32 7.8IL4, IFNA1, IFNA2, IL10, CD9, CD4
46indomethacin32 9 9 9.7TMPO, TNF, IL4, NOS2, IFNG, IFNA2
47alanine32 7.3APOE, CD4, GYPC, HLA-DRB1, HLA-A, HP
48actinomycin d32 7.1IFNG, HP, TNF, NOS2, CCR5, APOE
49cyclosporin a32 42 8.0IFNA1, CCR5, APOE, IFNG, HP, HLA-A
50tyrosine32 6.7HLA-A, IFNA2, IFNA1, CCR5, IL4, FCGR3A

GO Terms for genes affiliated with Herpes Zoster

Sources:
12Gene Ontology
See all sources

Cellular components related to herpes zoster according to GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1integral to lumenal side of endoplasmic reticulum membraneGO:0715569.1HLA-DRB1, HLA-B, HLA-A
2ER to Golgi transport vesicle membraneGO:0125079.1HLA-A, HLA-B, HLA-DRB1
3integral to plasma membraneGO:0058877.6TNF, HLA-DRB1, HLA-B, HLA-A, CCR5, GYPC
4extracellular spaceGO:0056157.5TNF, HP, IFNG, IFNA2, FAM3B, APOE
5external side of plasma membraneGO:0098976.9CD79A, TNF, HLA-DRB1, IFNG, CCR5, IL4

Biological processes related to herpes zoster according to GeneDecks:

(show all 24)
idNameGO IDScoreTop Affiliating Genes
1base-excision repair, gap-fillingGO:00628710.2POLE, POLD1
2DNA synthesis involved in DNA repairGO:00073110.2POLA1, POLD1, POLE
3telomere maintenance via semi-conservative replicationGO:03220110.1POLE, POLD1, POLA1
4telomere maintenance via recombinationGO:00072210.1POLA1, POLD1, POLE
5regulation of isotype switchingGO:04519110.0IL10, IL4
6receptor biosynthetic processGO:03280010.0TNF, IL10
7negative regulation of cytokine secretion involved in immune responseGO:0027409.8IL10, TNF
8positive regulation of vitamin D biosynthetic processGO:0605579.8IFNG, TNF
9entry into host cellGO:0302609.8CCR5, CD4
10positive regulation of calcidiol 1-monooxygenase activityGO:0605599.7TNF, IFNG
11type 2 immune responseGO:0420929.7IL4, IL10
12negative regulation of growth of symbiont in hostGO:0441309.6TNF, IFNG, IL10
13positive regulation of MHC class II biosynthetic processGO:0453489.5IFNG, IL4, IL10
14positive regulation of killing of cells of other organismGO:0517129.5NOS2, IFNG
15regulation of immune responseGO:0507769.5CD8A, FCGR3A, IL4, HLA-A, HLA-B
16innate immune response in mucosaGO:0022279.4NOS2, IL4
17positive regulation of membrane protein ectodomain proteolysisGO:0510449.4APOE, IFNG, TNF
18detection of bacteriumGO:0160459.4HLA-DRB1, HLA-B, HLA-A
19positive regulation of chemokine biosynthetic processGO:0450809.3TNF, IFNG, IL4
20B cell differentiationGO:0301839.2CD79A, IL10, IL4
21cellular response to lipopolysaccharideGO:0712229.1NOS2, IFNG, CCR5, IL10
22interferon-gamma-mediated signaling pathwayGO:0603338.9HLA-DRB1, HLA-B, HLA-A, IFNG
23cytokine-mediated signaling pathwayGO:0192218.4HLA-DRB1, HLA-B, HLA-A, IFNG, IFNA2
24immune responseGO:0069557.9MS4A1, HLA-DRB1, HLA-B, HLA-A, CCR5, IL4

Molecular functions related to herpes zoster according to GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1DNA-directed DNA polymerase activityGO:0038879.8POLA1, POLD1, POLE
24 iron, 4 sulfur cluster bindingGO:0515399.5REV3L, DPYD, POLA1, POLD1, POLE
3coreceptor activityGO:0150269.4CD8A, CD4, CCR5
4cytokine activityGO:0051258.3TNF, IFNG, IFNA2, FAM3B, IL4, IL10

Sources for Herpes Zoster

2CDC
11FMA
18HMDB
19ICD9CM
20KEGG
24MeSH
25MGI
27NCIt
28NDF-RT
31NINDS
32Novoseek
33OMIM
35PubMed
36QIAGEN
43UMLS