Aliases & Classifications for Hidradenitis

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Hidradenitis, Aliases & Descriptions:

Name: Hidradenitis 9 60
 
Hydradenitis 9


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Disease Ontology9 DOID:2282
ICD9CM27 705.83
MeSH33 D016575

Summaries for Hidradenitis

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Wikipedia:63 Hidradenitis is any disease in which the histologic abnormality is primarily an inflammatory infiltrate... more...

MalaCards based summary: Hidradenitis, also known as hydradenitis, is related to hidradenitis suppurativa and keratosis. An important gene associated with Hidradenitis is PSENEN (presenilin enhancer gamma secretase subunit), and among its related pathways are Notch signaling pathway and Development NOTCH1 mediated pathway for NF KB activity modulation. The compounds tazarotene and isotretinoin have been mentioned in the context of this disorder. Affiliated tissues include neutrophil, skin and myeloid, and related mouse phenotype mortality/aging.

Related Diseases for Hidradenitis

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Diseases related to Hidradenitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 81)
idRelated DiseaseScoreTop Affiliating Genes
1hidradenitis suppurativa32.3NCSTN, PSENEN
2keratosis29.8KRT10, KRT1
3skin disease29.7KRT1, KRT10
4acne10.8
5crohn's disease10.5
6pyoderma gangrenosum10.4
7pyoderma10.4
8arthritis10.3
9dowling-degos disease10.3
10cellulitis10.3
11psoriasis10.3
12degos disease10.3
13leukemia10.3
14spondyloarthropathy10.3
15dissecting cellulitis of the scalp10.3
16epidermolytic acanthoma10.2KRT1
17keratitis10.2
18lymphedema10.2
19arthropathy10.2
20elephantiasis10.2
21interstitial keratitis10.2
22blindness10.2
23pyoderma gangrenosum - acne - suppurative hidradenitis10.2
24steatocystoma multiplex10.1
25fox fordyce disease10.1
26urethritis10.1
27reactive arthritis10.1
28pachyonychia congenita10.1
29amyloidosis10.1
30nephrotic syndrome10.1
31vasculitis10.1
32arrhythmogenic right ventricular cardiomyopathy10.1DSC2, DSG2
33ichthyosis, cyclic, with epidermolytic hyperkeratosis10.0KRT10, KRT1
34bowen syndrome10.0KRT1, KRT10
35palmoplantar keratosis10.0KRT1, KRT10
36epidermolytic hyperkeratosis10.0KRT1, KRT10
37congenital ichthyosiform erythroderma10.0KRT1, KRT10
38epidermolysis bullosa simplex10.0KRT10, KRT1
39palmoplantar keratoderma, nonepidermolytic9.9KRT10, KRT1
40melkersson-rosenthal syndrome9.9
41lung cancer9.9
42obesity9.9
43hailey-hailey disease9.9
44anal fistula9.9
45behcet's disease9.9
46sinusitis9.9
47ulcerative colitis9.9
48reflex sympathetic dystrophy9.9
49sialadenitis9.9
50hypercalcemia9.9

Graphical network of the top 20 diseases related to Hidradenitis:



Diseases related to hidradenitis

Symptoms for Hidradenitis

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Drugs & Therapeutics for Hidradenitis

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Drug clinical trials:

Search ClinicalTrials for Hidradenitis

Search NIH Clinical Center for Hidradenitis

Genetic Tests for Hidradenitis

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Anatomical Context for Hidradenitis

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MalaCards organs/tissues related to Hidradenitis:

31
Neutrophil, Skin, Myeloid, Lymph node, Lung, Breast, Endothelial, Pituitary

Animal Models for Hidradenitis or affiliated genes

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MGI Mouse Phenotypes related to Hidradenitis:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107687.7KRT1, KRT10, NCSTN, PSENEN, DSG2

Publications for Hidradenitis

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Articles related to Hidradenitis:

(show top 50)    (show all 612)
idTitleAuthorsYear
1
Hidradenitis Suppurativa: New Opportunities for an Orphan Skin Disease. (25796270)
2015
2
Hidradenitis Suppurativa: a pilot study to determine patients capability to self-assess their Hurley stage. (25354349)
2014
3
Association of Metabolic Syndrome and Hidradenitis Suppurativa. (25229996)
2014
4
Successful treatment of severe hidradenitis suppurativa with anakinra. (23966107)
2013
5
Diseases associated with hidranitis suppurativa: part 2 of a series on hidradenitis. (24011308)
2013
6
Phenotypic heterogeneity in hidradenitis suppurativa (acne inversa): classification is an essential step toward personalized therapy. (23673498)
2013
7
Hidradenitis suppurativa and multiple dermatofibromas in a patient with ulcerative colitis. (24330184)
2013
8
Absence of pathogenic I^-secretase mutations in a South Wales cohort of familial and sporadic hidradenitis suppurativa (acne inversa). (23013355)
2013
9
Treatment of moderate to severe hidradenitis suppurativa. (23817709)
2013
10
Islanded perforator flaps in the reconstruction of hidradenitis suppurativa defects. (23303517)
2013
11
Predicting response to anti-TNF-alpha treatment in Hidradenitis suppurativa. (23362964)
2013
12
Axillary hidradenitis. (23359851)
2013
13
Clinical practice. Hidradenitis suppurativa. (22236226)
2012
14
Interstitial keratitis secondary to severe hidradenitis suppurativa responding to adalimumab. (22146546)
2012
15
Alterations in leucocyte subsets and histomorphology in normal-appearing perilesional skin and early and chronic hidradenitis suppurativa lesions. (21929531)
2012
16
Radical surgical excision and use of lateral thoracic flap for intractable axillary hidradenitis suppurativa. (23233895)
2012
17
Bacteriology of hidradenitis suppurativa exacerbations and deep tissue cultures obtained during carbon dioxide laser treatment. (22098253)
2012
18
Surgical treatment of chronic hidradenitis suppurativa in the gluteal and perianal regions. (23373365)
2012
19
The thoracodorsal artery perforator flap in the treatment of axillary hidradenitis suppurativa: effect on preservation of arm abduction. (21921770)
2011
20
The perils of a defective medical communication: fatal neglected squamous cell carcinoma arising in perineal hidradenitis suppurativa. (21897818)
2011
21
Management of regional hidradenitis suppurativa with vacuum-assisted closure and split thickness skin grafts. (21587057)
2011
22
Interstitial keratitis secondary to severe hidradenitis suppurativa: a case report and literature review. (20628295)
2010
23
Hyperbaric oxygen therapy for the management of postsurgical wounds in hidradenitis suppurativa. (21352679)
2010
24
Hidradenitis suppurativa (or Acne inversa) with autosomal dominant inheritance is not linked to chromosome 1p21.1-1q25.3 region. (20698881)
2010
25
Effective long-term control of refractory hidradenitis suppurativa with adalimumab after failure of conventional therapy. (21091684)
2010
26
Hidradenitis suppurativa. (20883920)
2010
27
Biologic drugs for the treatment of hidradenitis suppurativa: an evidence-based review. (20510761)
2010
28
Lymph nodes in hidradenitis suppurativa. (19365106)
2009
29
Etanercept for the treatment of hidradenitis suppurativa. (19197548)
2009
30
Hidradenitis suppurativa: importance of early treatment; efficient treatment with electrosurgery. (18093196)
2008
31
Quality of life impairment in hidradenitis suppurativa: a study of 61 cases. (17097366)
2007
32
Real-time compound imaging ultrasound of hidradenitis suppurativa. (17958586)
2007
33
A hidradenitis suppurativa related SAPHO case associated with features resembling spondylarthropathy and proteinuria. (16680392)
2007
34
The cutting edge. Severe hidradenitis suppurativa treated with adalimumab. (16982997)
2006
35
Surgical treatment of hidradenitis suppurativa: case series and review of the literature. (16984573)
2006
36
Clindamycin and rifampicin combination therapy for hidradenitis suppurativa. (16634904)
2006
37
Etanercept: effective in the management of hidradenitis suppurativa. (16536817)
2006
38
Treatment of long-standing extensive perianal hidradenitis suppurativa using double rotation plasty, V-Y plasty and free grafts. (12838364)
2004
39
Hidradenitis suppurativa. (12457209)
2003
40
Vulvar hidradenitis suppurativa. Immunohistochemical evaluation of apocrine and eccrine involvement. (12380447)
2002
41
Split-thickness skin grafts and negative-pressure dressings in the treatment of axillary hidradenitis suppurativa. (12479426)
2002
42
Hidradenitis suppurativa. (11193069)
2000
43
The natural history of hidradenitis suppurativa. (11305381)
2000
44
Neutrophilic eccrine hidradenitis. (10856664)
2000
45
Cigarette smoking as a triggering factor of hidradenitis suppurativa. (10393449)
1999
46
Pyoderma gangrenosum associated with cystic acne and hidradenitis suppurativa controlled by adding minocycline and sulfasalazine to the treatment regimen. (8726710)
1996
47
Cyclosporin-responsive hidradenitis suppurativa. (7636825)
1995
48
Surgical management of severe mammary hidradenitis suppurativa. (3341719)
1988
49
Hidradenitis suppurativa of the anogenital region: response to isotretinoin. (3422131)
1988
50
Fox-Fordyce disease with hidradenitis suppurativa. (13563958)
1958

Variations for Hidradenitis

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Expression for genes affiliated with Hidradenitis

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Search GEO for disease gene expression data for Hidradenitis.

Pathways for genes affiliated with Hidradenitis

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Pathways related to Hidradenitis according to GeneCards Suite gene sharing:

(show all 15)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Delta-Notch Signaling Pathway36
Notch Signaling Pathway36
9.6NCSTN, PSENEN
2
Show member pathways
Development Notch Signaling Pathway58
Transcription Sin3 and NuRD in transcription regulation58
9.6NCSTN, PSENEN
3
Show member pathways
9.6NCSTN, PSENEN
4
Show member pathways
9.6NCSTN, PSENEN
5
Show member pathways
Alzheimers Disease36
9.6NCSTN, PSENEN
69.6NCSTN, PSENEN
79.6NCSTN, PSENEN
89.6PSENEN, NCSTN
9
Show member pathways
9.6PSENEN, NCSTN
10
Show member pathways
9.6NCSTN, PSENEN
11
Show member pathways
9.6NCSTN, PSENEN
129.6NCSTN, PSENEN
13
Show member pathways
Notch signaling pathway36
9.6NCSTN, PSENEN
149.6NCSTN, PSENEN
15
Show member pathways
Arrhythmogenic right ventricular cardiomyopathy36
9.3DSC2, DSG2

Compounds for genes affiliated with Hidradenitis

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Sources:
43Novoseek, 12DrugBank, 49PharmGKB, 24HMDB
See all sources

Compounds related to Hidradenitis according to GeneCards Suite gene sharing:

idCompoundScoreTop Affiliating Genes
1tazarotene43 1210.2KRT1, KRT10
2isotretinoin43 1210.2KRT1, KRT10
3isoleucine439.1KRT1, KRT10
4bromodeoxyuridine439.1KRT1, KRT10
5hematoxylin439.0KRT10, KRT1
6calcium43 49 24 1210.7KRT1, KRT10, DSG2, DSC2

GO Terms for genes affiliated with Hidradenitis

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Cellular components related to Hidradenitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1desmosomeGO:00300579.2DSG2, DSC2
2keratin filamentGO:00450959.1KRT10, KRT1
3extracellular vesicular exosomeGO:00700627.5DSC2, DSG2, NCSTN, KRT10, KRT1
4plasma membraneGO:00058867.3KRT1, DSC2, DSG2, PSENEN, NCSTN

Biological processes related to Hidradenitis according to GeneCards Suite gene sharing:

(show all 12)
idNameGO IDScoreTop Affiliating Genes
1amyloid precursor protein catabolic processGO:00429879.9NCSTN, PSENEN
2membrane protein intracellular domain proteolysisGO:00312939.8NCSTN, PSENEN
3membrane protein ectodomain proteolysisGO:00065099.8NCSTN, PSENEN
4Notch receptor processingGO:00072209.7PSENEN, NCSTN
5protein processingGO:00164859.7NCSTN, PSENEN
6positive regulation of catalytic activityGO:00430859.6NCSTN, PSENEN
7bundle of His cell to Purkinje myocyte communicationGO:00860699.6DSG2, DSC2
8ventricular cardiac muscle cell action potentialGO:00860059.5DSC2, DSG2
9apoptotic signaling pathwayGO:00971909.5PSENEN, NCSTN
10regulation of heart rate by cardiac conductionGO:00860919.5DSG2, DSC2
11homophilic cell adhesionGO:00071569.3DSG2, DSC2
12Notch signaling pathwayGO:00072199.3NCSTN, PSENEN

Products for genes affiliated with Hidradenitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Hidradenitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet