MCID: HDR004
MIFTS: 37

Hidradenoma

Categories: Skin diseases, Cancer diseases, Endocrine diseases

Aliases & Classifications for Hidradenoma

MalaCards integrated aliases for Hidradenoma:

Name: Hidradenoma 12 52 14
Adenoma, Sweat Gland 42 69
Benign Neoplasm of Sweat Gland 69
Hidradenoma of Skin 12
Sweat Gland Adenoma 12
Eccrine Acrospiroma 69
Syringoadenoma 12

Classifications:



Summaries for Hidradenoma

MalaCards based summary : Hidradenoma, also known as adenoma, sweat gland, is related to spiradenoma and papillary hidradenoma. An important gene associated with Hidradenoma is MAML2 (Mastermind Like Transcriptional Coactivator 2), and among its related pathways/superpathways are Development ERBB-family signaling and T cell receptor signaling pathway. Affiliated tissues include skin, breast and lymph node, and related phenotype is Decreased cell migration.

Wikipedia : 72 Hidradenoma (also known as acrospiroma, from akral \"peripheral\" + spiroma \"epithelial tumor of sweat... more...

Related Diseases for Hidradenoma

Diseases related to Hidradenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 118)
id Related Disease Score Top Affiliating Genes
1 spiradenoma 29.9 ANXA11 PIK3CA
2 papillary hidradenoma 12.2
3 nodular hidradenoma 12.0
4 clear cell hidradenoma 12.0
5 vulvar nodular hidradenoma 11.7
6 hidradenocarcinoma 11.7
7 acrospiroma 11.6
8 eccrine acrospiroma 11.2
9 laryngeal mucoepidermoid carcinoma 10.6 CRTC1 MAML2
10 mucoepidermoid thyroid carcinoma 10.6 CRTC1 MAML2
11 fallopian tube transitional cell carcinoma 10.6 CRTC1 MAML2
12 eccrine papillary adenoma 10.6 CRTC1 MAML2
13 webster deming syndrome 10.6 CRTC1 MAML2
14 rete testis neoplasm 10.5 CRTC1 MAML2
15 plasmodium ovale malaria 10.5 CRTC1 MAML2
16 gastric papillary adenocarcinoma 10.5 MUC1 PIK3CA
17 uniparental disomy of chromosome 11 10.3 PIK3CA VIM
18 cowden syndrome 6 10.3 AKT1 PIK3CA
19 2q31.1 microdeletion syndrome 10.3 MUC1 VIM
20 myeloid/lymphoid neoplasm associated with pdgfra rearrangement 10.3 MUC1 VIM
21 spleen angiosarcoma 10.3 MUC1 VIM
22 myoma 10.3 MUC1 VIM
23 laryngeal neuroendocrine tumor 10.3 MUC1 VIM
24 mannose-binding lectin protein deficiency 10.3 MUC1 VIM
25 vulvar angiokeratoma 10.3 MUC1 VIM
26 noninvasive malignant thymoma 10.3 MUC1 VIM
27 reticular pattern testicular yolk sac tumor 10.2 MUC1 VIM
28 pyoderma 10.2 MUC1 VIM
29 pancreatic intraductal papillary-colloid carcinoma 10.2 MUC1 VIM
30 bladder colloid adenocarcinoma 10.2 MUC1 VIM
31 cellular ependymoma 10.2 MUC1 VIM
32 lice infestation 10.2 MUC1 VIM
33 lymphangiosarcoma 10.2 MUC1 VIM
34 ganglioglioma 10.2 MUC1 VIM
35 anaplastic oligodendroglioma 10.2 MUC1 VIM
36 persian gulf syndrome 10.2 MUC1 VIM
37 diffuse meningeal melanocytosis 10.2 MUC1 VIM
38 fallopian tube germ cell cancer 10.2 MUC1 VIM
39 ovary papillary carcinoma 10.2 MUC1 VIM
40 childhood pleomorphic rhabdomyosarcoma 10.2 MUC1 VIM
41 vulvar squamous papilloma 10.2 MUC1 VIM
42 spindle cell liposarcoma 10.2 MUC1 VIM
43 sebaceous adenoma 10.2 MUC1 VIM
44 subependymal glioma 10.2 MUC1 VIM
45 short-rib thoracic dysplasia 12 10.2 MUC1 VIM
46 ovarian mucinous adenocarcinoma 10.2 MUC1 VIM
47 coronary restenosis 10.2 MUC1 VIM
48 extraskeletal mesenchymal chondrosarcoma 10.2 MUC1 VIM
49 vaginal adenoma 10.2 CRTC1 MAML2 MUC1
50 spondyloepimetaphyseal dysplasia, isidor type 10.2 MUC1 VIM

Graphical network of the top 20 diseases related to Hidradenoma:



Diseases related to Hidradenoma

Symptoms & Phenotypes for Hidradenoma

GenomeRNAi Phenotypes related to Hidradenoma according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased cell migration GR00055-A-1 8.92 AKT1 MUC1 PIK3CA VIM

Drugs & Therapeutics for Hidradenoma

Search Clinical Trials , NIH Clinical Center for Hidradenoma

Cochrane evidence based reviews: adenoma, sweat gland

Genetic Tests for Hidradenoma

Anatomical Context for Hidradenoma

MalaCards organs/tissues related to Hidradenoma:

39
Skin, Breast, Lymph Node, Salivary Gland, Lung, Heart, Smooth Muscle

Publications for Hidradenoma

Articles related to Hidradenoma:

(show top 50) (show all 293)
id Title Authors Year
1
Sonographic Characteristics of Apocrine Nodular Hidradenoma of the Skin. ( 28880402 )
2017
2
Nodular hidradenoma: Dermoscopic presentation. ( 28087028 )
2017
3
Hidradenoma of the Chin. ( 28570408 )
2017
4
Mucinous hidradenoma in a child-A case report and review of the literature. ( 28429507 )
2017
5
Hidradenoma papilliferum of the vulva in a postpartum woman: A case report. ( 28287283 )
2017
6
Case of chondroid syringoma mimicking as nodular hidradenoma: A diagnostic pitfall on cytopathology. ( 28772003 )
2017
7
Molecular alterations in lesions of anogenital mammary-like glands and their mammary counterparts including hidradenoma papilliferum, intraductal papilloma, fibroadenoma and phyllodes tumor. ( 28648934 )
2017
8
A case of cutaneous metastatic lung cancer difficult to distinguish from malignant nodular hidradenoma. ( 28664659 )
2017
9
Clear cell hidradenoma of the breast with MAML2 gene rearrangement. ( 27914681 )
2017
10
Malignant Clear Cell Hidradenoma of the Breast. ( 28409065 )
2017
11
Poroid Hidradenoma: An Uncommon Cutaneous Adnexal Neoplasm. ( 28216741 )
2017
12
The utility of using immunohistochemistry in the differentiation of metastatic, cutaneous clear cell renal cell carcinoma and clear cell hidradenoma. ( 28374447 )
2017
13
A Rare Case of Cutaneous Oncocytic Hidradenoma. ( 28035705 )
2016
14
PIK3CA and AKT1 mutations in hidradenoma papilliferum. ( 27742746 )
2016
15
Hidradenoma Papilliferum: A Case Report of an Uncommon Perianal Lesion. ( 26874122 )
2016
16
Hidradenoma Papilliferum With Oncocytic Metaplasia: A Histopathological and Immunohistochemical Study. ( 27097337 )
2016
17
A Weeping Tumor in a Young Girl: An Unusual Presentation of Nodular Hidradenoma. ( 27293255 )
2016
18
Lymph Node Involvement by a Clear Cell Nodular Hidradenoma-Like Tumor of Uncertain Malignant Potential. ( 28033155 )
2016
19
A case of nodular hidradenoma of the auricle mimicking squamous cell carcinoma. ( 27350422 )
2016
20
Dermoscopy of Nodular Hidradenoma, a Great Masquerader: A Morphological Study of 28 Cases. ( 26606241 )
2016
21
Ultrasound Image of Poroid Hidradenoma. ( 26762692 )
2016
22
Nodular hidradenoma arising on the site of a BCG scar. ( 27523405 )
2016
23
Giant metastasizing malignant hidradenoma in a child. ( 27730041 )
2016
24
LYMPH NODE LOCATION OF A CLEAR CELL HIDRADENOMA: REPORT OF A PATIENT AND REVIEW OF LITERATURE. ( 27080562 )
2016
25
Mutations of cancer-related genes in benign tumors: the example of hidradenoma papilliferum. ( 27865794 )
2016
26
Tubulopapillary Hidradenoma-like Tumour of the Mandible: A Case Report and Literature Review. ( 27943162 )
2016
27
Vulvar hidradenoma papilliferum (HP) is located on the sites of mammary-like anogenital glands (MLAGs): Analysis of the photographs of 52 tumors. ( 26944596 )
2016
28
Frequent PIK3CA Activating Mutations in Hidradenoma Papilliferums. ( 27184479 )
2016
29
Cutaneous hidradenoma: a study of 21 neoplasms revealing neither correlation between the cellular composition and CRTC1-MAML2 fusions nor presence of CRTC3-MAML2 fusions. ( 27402217 )
2016
30
Ultrasonographic diagnosis of nodular hidradenoma. ( 26662046 )
2016
31
Hidradenoma masquerading digital ganglion cyst: A rare phenomenon. ( 27625783 )
2016
32
Hidradenoma Papilliferum: A Clinicopathologic Study of 264 Tumors From 261 Patients, With Emphasis on Mammary-Type Alterations. ( 26863059 )
2016
33
Atypical Hidradenoma Mimicking Primary Mammary Carcinoma on Breast Fine-Needle Aspiration: A Case Report with Long-Term Follow-Up. ( 27010690 )
2016
34
A reddish nodule with viscous fluid secretion. Solida89cystic hidradenoma (SCH). ( 26266940 )
2016
35
Rare Adnexal Tumor of the Breast: Poroid Hidradenoma. ( 27943519 )
2016
36
Hidradenoma of the Breast: A Source of Diagnostic Confusion. ( 26391316 )
2015
37
Nodular hidradenoma of left toe. ( 25671057 )
2015
38
Hidradenoma papilliferum associated with pregnancy: a case report. ( 26265265 )
2015
39
Mutations in genes encoding PI3K-AKT and MAPK signaling define anogenital papillary hidradenoma. ( 26493284 )
2015
40
Clear Cell Hidradenoma of the Ear Lobule: An Unusual Site of Presentation. ( 26435960 )
2015
41
Skin ultrasound examination proves useful in diagnosing two cases of solid cystic hidradenoma. ( 22998357 )
2014
42
Hidradenoma papilliferum of the vulva in association with an anogenital mammary-like gland. ( 24617304 )
2014
43
Malignant nodular hidradenoma of scalp. ( 25288856 )
2014
44
Ectopic hidradenoma papilliferum dermoscopically mimicking a blue nevus: a case report and review of the literature. ( 23557245 )
2014
45
Hidradenoma papilliferum, diagnostic challenge: a case. ( 25387849 )
2014
46
A case of tubulopapillary hidradenoma on the face. ( 25269926 )
2014
47
The aesthetic and oncological challenges in the management of an atypical nodular hidradenoma of the pinna. ( 25114470 )
2014
48
What is your diagnosis? Clear cell hidradenoma. ( 25566574 )
2014
49
Nodular hidradenoma of the wrist with spontaneous regression in a 7-month-old infant. ( 25266990 )
2014
50
Nodular hidradenoma of the scalp: A cytomorphological evaluation on fine needle aspiration cytology. ( 25382530 )
2014

Variations for Hidradenoma

Expression for Hidradenoma

Search GEO for disease gene expression data for Hidradenoma.

Pathways for Hidradenoma

Pathways related to Hidradenoma according to GeneCards Suite gene sharing:

(show all 28)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.26 AKT1 MUC1 PIK3CA
2
Show member pathways
12.19 AKT1 PIK3CA VIM
3 12.18 AKT1 CRTC1 PIK3CA
4 11.96 AKT1 PIK3CA VIM
5
Show member pathways
11.62 AKT1 PIK3CA
6 11.35 AKT1 PIK3CA
7 11.33 AKT1 PIK3CA
8 11.3 AKT1 PIK3CA
9 11.29 AKT1 PIK3CA
10 11.26 AKT1 PIK3CA
11 11.24 AKT1 PIK3CA
12 11.11 AKT1 PIK3CA
13 11.09 AKT1 PIK3CA
14 11.05 AKT1 PIK3CA
15
Show member pathways
11.03 AKT1 PIK3CA
16 11.03 AKT1 PIK3CA
17 11 AKT1 PIK3CA
18 10.97 AKT1 PIK3CA
19 10.94 AKT1 PIK3CA
20 10.87 AKT1 PIK3CA
21 10.86 AKT1 MUC1 VIM
22 10.85 AKT1 PIK3CA
23 10.78 AKT1 PIK3CA
24 10.73 AKT1 PIK3CA
25 10.68 AKT1 PIK3CA
26 10.54 AKT1 PIK3CA
27 10.41 AKT1 PIK3CA
28 10.21 AKT1 VIM

GO Terms for Hidradenoma

Biological processes related to Hidradenoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein kinase B signaling GO:0043491 9.32 AKT1 PIK3CA
2 energy homeostasis GO:0097009 9.16 CRTC1 PIK3CA
3 phosphatidylinositol 3-kinase signaling GO:0014065 8.96 AKT1
4 negative regulation of macroautophagy GO:0016242 8.96 AKT1 PIK3CA
5 anoikis GO:0043276 8.62 AKT1 PIK3CA

Sources for Hidradenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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