MCID: HDR004
MIFTS: 41

Hidradenoma malady

Summaries for Hidradenoma

Sources:
64Wikipedia, 33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:64 Hidradenoma is a cutaneous condition, primarily occurring in adult women, that is a form of benign... more...

MalaCards: Hidradenoma, also known as hidradenoma morphology, is related to clear cell hidradenoma and syringocystadenoma papilliferum. An important gene associated with Hidradenoma is MUC1 (mucin 1, cell surface associated), and among its related pathways are EGFR Signaling Pathway and Alpha6-Beta4 Integrin Signaling Pathway. The compounds hematoxylin and s 100 have been mentioned in the context of this disorder.

Aliases & Classifications for Hidradenoma

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 61UMLS, 57SNOMED-CT, 35MeSH, 40NCIt
See all sources

Aliases & Descriptions:

hidradenoma 8 10 45
hidradenoma morphology 8
adenoma, sweat gland 61
sweat gland adenoma 8
hidradenoma of skin 8
syringocystadenoma 61
syringoadenoma 8


External Ids:

Disease Ontology8 DOID:3896
MeSH35 D006607
NCIt40 C7560, C7563

Related Diseases for Hidradenoma

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Hidradenoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 117)
idRelated DiseaseScoreTop Affiliating Genes
1clear cell hidradenoma31.2SGTA
2syringocystadenoma papilliferum30.4CLEC2A, PIP
3adenocarcinoma30.3VIM, S100A6, PIP, CREB1, EGFR, MUC1
4adenoma30.1S100A6, CREB1, MUC1
5syringoma29.9MUC1
6spiradenoma29.9CLEC2A
7neurofibromatosis29.8CREB1
8hidrocystoma29.8SGTA, PIP
9pleomorphic adenoma29.8VIM, MUC1, ERBB2
10mucoepidermoid carcinoma29.8CRTC1, CREB1, EGFR, MAML2, MUC1
11squamous cell carcinoma29.8VIM, S100A6, PIP, EGFR, MUC1, KRT10
12nodular hidradenoma10.8
13papillary hidradenoma10.5
14apocrine adenoma10.4
15hidradenocarcinoma10.3
16procarcinoma10.2
17eccrine acrospiroma10.2
18vulvar nodular hidradenoma10.2
19vulva adenocarcinoma10.2
20acrospiroma10.2
21cystadenoma10.1
22myoepithelioma10.1
23nodular malignant melanoma10.1
24thymic carcinoma10.0MUC1
25papilloma10.0KRT10
26hemangioblastoma10.0MUC1
27wilms tumor10.0VIM
28angiomyolipoma10.0VIM
29cervical adenosquamous carcinoma10.0CRTC1, MAML2
30epithelial-myoepithelial carcinoma10.0MAML2, CRTC1
31alopecia10.0CLEC2A
32cervical squamous cell carcinoma10.0KRT10
33cutaneous mucoepidermoid carcinoma10.0CRTC1, MAML2
34lacrimal gland cancer10.0CRTC1, MAML2
35lipoadenoma10.0CRTC1, MAML2
36esophageal cancer10.0EGFR
37necrotizing sialometaplasia10.0CRTC1, MAML2
38acanthoma10.0CLEC2A
39fibrosarcoma10.0VIM
40clear cell ependymoma10.0MUC1, VIM
41mesenchymal chondrosarcoma10.0VIM, MUC1
42spindle cell carcinoma10.0MUC1, VIM
43neurofibroma10.0MUC1, VIM
44giant cell glioblastoma10.0EGFR
45spindle cell sarcoma10.0VIM, MUC1
46clear cell sarcoma10.0CREB1
47rhabdoid tumor10.0VIM, MUC1
48keratosis10.0KRT10, CLEC2A
49angiosarcoma10.0MUC1, VIM
50leydig cell tumor10.0CREB1

Graphical network of the top 20 diseases related to Hidradenoma:



Diseases related to hidradenoma

Clinical Features for Hidradenoma

Drugs & Therapeutics for Hidradenoma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Hidradenoma

Drug clinical trials:

Search ClinicalTrials for Hidradenoma

Search NIH Clinical Center for Hidradenoma

Search CenterWatch for Hidradenoma

Genetic Tests for Hidradenoma

Anatomical Context for Hidradenoma

Animal Models for Hidradenoma or affiliated genes

Sources:
28inGenious Targeting Laboratory
See all sources

Publications for Hidradenoma

Sources:
51PubMed
See all sources

Articles related to Hidradenoma:

(show top 50)    (show all 237)
idTitleAuthorsYear
1
Skin ultrasound examination proves useful in diagnosing two cases of solid cystic hidradenoma. (22998357)
2014
2
Benign hidradenoma masquerading as ductal breast cancer-a rare case of false-positive recurrence in cancer follow-up. (24102904)
2013
3
Ulcerated hidradenoma papilliferum. (23347308)
2013
4
Hidradenoma papilliferum with mixed histopathologic features of syringocystadenoma papilliferum and anogenital mammary-like glands: report of a case and review of the literature. (22262361)
2012
5
Cutaneous myoepithelioma arising within hidradenoma of the scalp. (22077442)
2012
6
Ectopic hidradenoma papilliferum of the breast: ultrasound finding. (21847412)
2011
7
A giant ectopic hidradenoma papilliferum in a Niger delta region of Nigeria. (22355505)
2011
8
Poroid hidradenoma. (21703162)
2011
9
Diagnosis of hidradenoma papilliferum of the vulva on cytologic smears: a case report. (21053567)
2010
10
Fine-needle aspiration cytology of apocrine hidradenoma. (20698151)
2010
11
Malignant nodular hidradenoma of the eyelid: a rare sweat gland tumor. (21180442)
2010
12
Ectopic hidradenoma papilliferum. (21197082)
2010
13
A skin tumor in a young girl. Diagnosis: Clear cell hidradenoma. (20657141)
2010
14
Immunophenotypic aspects of cylindroma and nodular hidradenoma. (19796089)
2010
15
Nodular hidradenoma of the breast: A case report with literature review. (23133109)
2009
16
Malignant nodular hidradenoma on the scalp: report of a case with fine needle aspiration cytology features and histologic correlation. (19798887)
2009
17
Hidradenomas and a hidradenocarcinoma of the scalp managed using Mohs micrographic surgery and a multidisciplinary approach: case reports and review of the literature. (19215270)
2009
18
Cytologic features of hidradenoma in fine needle aspiration biopsies. (19365971)
2009
19
Adenocarcinoma in situ arising in vulvar papillary hidradenoma: report of 2 cases. (18580327)
2008
20
Bartholin's abscess arising within hidradenoma papilliferum of the vulva: a case report. (18959791)
2008
21
Malignant clear cell hidradenoma of the vulva: report of a unique case and review of the literature. (18156989)
2008
22
An uncommon perianal nodule: hidradenoma papilliferum. (17347625)
2007
23
Mucinous hidradenoma: a report of three cases. (17518780)
2007
24
Giant apocrine hidradenoma of the breast. (17214802)
2007
25
Malignant hidradenoma: a report of two cases and review of the literature. (16821590)
2006
26
Clear cell hidradenoma. (16631962)
2006
27
Malignant hidradenoma of the medial canthus with orbital and intracranial extension. (16714943)
2006
28
Asymptomatic slowly enlarging nodule on the trunk: eccrine hidradenoma. (15009319)
2004
29
Vulvar poroid hidradenoma. (12454609)
2002
30
Clear cell hidradenoma in a young girl. (10727324)
2000
31
MRI appearance of clear cell hidradenoma. (10197457)
1999
32
Clear cell hidradenoma of the eyelid: a case report. (10862299)
1999
33
Nodular hidradenoma. A report of three cases and review of the literature. (9537017)
1998
34
Clear cell hidradenoma of the second digit: a review of the literature with case presentation. (9031022)
1997
35
Fine needle aspiration cytology of malignant hidradenoma. (8395754)
1993
36
Clear cell hidradenoma: a tumor with basaliomatous changes in the overlying epidermis and follicular infundibula of surrounding skin. (1328338)
1992
37
Eccrine acrospiroma (clear cell hidradenoma) of the eyelid. Immunohistochemical and ultrastructural features. (1708858)
1991
38
Malignant hidradenoma--a case report demonstrating insidious histological and clinical progression. (1666865)
1991
39
Acquired Gaucher cells located in dermis near a malignant hidradenoma. (2834849)
1988
40
Hidradenoma with intracranial involvement. (6330311)
1984
41
Epidermoid hidradenoma. A clinicopathologic study. (6292273)
1982
42
Identification of papillary hidradenoma of the vulva by imprint cytology. (6254297)
1980
43
Clear cell hidradenoma. A clinical and pathologic description with a case history. (168244)
1975
44
Papillary hidradenoma of the vulva: a clinicopathologic study of 69 cases. (4325819)
1971
45
Eruptive hidradenoma and syringoma. Histological, histochemical, and electron microscopic studies. (4293320)
1967
46
HIDRADENOMA OF THE ANAL CANAL. (14280233)
1965
47
Hidradenoma of the vulva. (12999428)
1952
48
Hidradenoma of the vulva. (14771199)
1950
49
Hidradenoma of the vulva. (18106314)
1948
50
Sweet gland tumors of the vulva, benign (hidradenoma) and malignant (adenocarcinoma). (21007065)
1945

Genetic Variations for Hidradenoma

Expression for genes affiliated with Hidradenoma

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Hidradenoma

Search GEO for disease gene expression data for Hidradenoma.

Pathways for genes affiliated with Hidradenoma

Sources:
56SinoBiological, 38NCBI BioSystems Database, 12EMD Millipore, 52QIAGEN
See all sources

Compounds for genes affiliated with Hidradenoma

Sources:
45Novoseek, 11DrugBank, 60Tocris Bioscience, 50PharmGKB, 24HMDB, 29IUPHAR, 2BitterDB
See all sources

Compounds related to Hidradenoma according to GeneCards/GeneDecks:

(show all 49)
idCompoundScoreTop Affiliating Genes
1hematoxylin4510.4KRT10, VIM
2s 1004510.4VIM, MUC1
3Afatinib1110.3EGFR, ERBB2
4jnj 28871063 hydrochloride6010.3EGFR, ERBB2
5ag 4906010.3EGFR, ERBB2
6ag 1478 hydrochloride6010.3EGFR, ERBB2
7iressa6010.3EGFR, ERBB2
8pd1587804510.3EGFR, ERBB2
9pertuzumab45 50 1112.3EGFR, ERBB2
10pki-1664510.3EGFR, ERBB2
11hrgbeta14510.3EGFR, ERBB2
12eosin4510.3KRT10, MUC1, VIM
13quinazoline4510.3EGFR, ERBB2
14erbstatin4510.2EGFR, ERBB2
15everolimus50 45 1112.1EGFR, ERBB2
16reticulin4510.1VIM, MUC1
17pd1530354510.1EGFR, KRT10, ERBB2
18trastuzumab45 50 1112.1EGFR, MUC1, ERBB2
19ganciclovir45 1111.1ERBB2, CREB1, VIM
20anastrozole45 1111.0EGFR, ERBB2
214-hydroxytamoxifen4510.0ERBB2, EGFR, VIM
22gemcitabine45 50 1112.0EGFR, MUC1, ERBB2
23biotin45 11 2412.0ERBB2, MUC1, VIM
24gefitinib45 50 1112.0ERBB2, EGFR, VIM
25ag 14784510.0ERBB2, EGFR, CREB1
26bexarotene45 29 1112.0EGFR, KRT10
27polyethylene glycol459.9AZGP1, MUC1, ERBB2
28gf 109203x45 6010.9CREB1, EGFR, KRT10
29chloramphenicol45 2 1111.9ERBB2, MUC1, CREB1, VIM
30thymidylate459.9VIM, EGFR, ERBB2
31retinoid459.8VIM, CREB1, EGFR, KRT10
32hydrocortisone45 2 60 1112.8ERBB2, MUC1, VIM
33capecitabine45 50 1111.8EGFR, ERBB2
34azathioprine45 50 2 1112.7CREB1, S100A6, VIM
35rapamycin459.7ERBB2, EGFR, CREB1, VIM
36mucicarmine459.6MUC1, PIP, VIM
37b 723459.6MUC1, PIP, VIM
38agar459.6VIM, CREB1, EGFR, MUC1, ERBB2
39dexamethasone45 50 29 1112.5ERBB2, KRT10, MUC1, CREB1, VIM
40adriamycin459.4ERBB2, MUC1, VIM
41progestin459.4VIM, S100A6, EGFR, MUC1, ERBB2
42retinoic acid45 2410.1VIM, S100A6, CREB1, EGFR, MUC1, KRT10
43tamoxifen45 50 29 1112.0VIM, PIP, EGFR, MUC1, ERBB2
44estradiol45 11 2410.9MUC1, CREB1, PIP, VIM
45serine458.9ERBB2, KRT10, MUC1, EGFR, CREB1, VIM
46steroid458.6ERBB2, KRT10, CREB1, PIP, S100A6
47paraffin458.3ERBB2, KRT10, MUC1, EGFR, PIP, S100A6
48progesterone45 60 29 11 2412.3VIM, S100A6, PIP, EGFR, MUC1, KRT10
49testosterone45 60 11 2411.3VIM, S100A6, PIP, CREB1, EGFR, MUC1

GO Terms for genes affiliated with Hidradenoma

Sources:
16Gene Ontology
See all sources

Cellular components related to Hidradenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1apical plasma membraneGO:0163248.6NHS, ERBB2, MUC1, PIP
2cytoplasmGO:0057377.4S100A6, CRTC1, EGFR, SH3GL1, ANXA11, MUC1

Biological processes related to Hidradenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of transcription by competitive promoter bindingGO:0109449.7MUC1, CREB1
2modulation by virus of host morphology or physiologyGO:0190489.1SGTA, CREB1, CRTC1, VIM

Molecular functions related to Hidradenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1receptor signaling protein tyrosine kinase activityGO:0047169.9ERBB2, EGFR
2epidermal growth factor-activated receptor activityGO:0050069.8ERBB2, EGFR
3S100 protein bindingGO:0445489.4ANXA11, S100A6

Products for genes affiliated with Hidradenoma

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Hidradenoma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet