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Drugs for High Bone Mass Osteogenesis Imperfecta (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB): (show all 14)
| id | | Name | Status | Phase | Clinical Trials | Cas Number | PubChem Id |
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| 1 | | Ergocalciferol | approved, nutraceutical | Phase 4 | 1281 | 50-14-6 | 5280793 | 'Ergosterol irradiated' (+)-Vitamin D2 (3-beta,5Z,7E,22E)-9,10-Secoergosta-5,7,10,(19),22-tetraen-3-ol (3S,5Z,7E,14xi,17alpha,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol (3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol (3S,5Z,7E,22E)-9,10-secoergosta-5,7,10,22-tetraen-3-ol (3beta,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol (3beta,5Z,7e,22e)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol (5E,7E,22E)-9,10-Secoergosta-5,7,10,22-tetraen-3-ol (5Z,7E,22E)-(3S)-9,10-seco-5,7,10(19),22-ergostatetraen-3-ol (5Z,7E,22E)-(3S)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol (5Z,7e,22e)-(3S)-9,10-Seco-5,7,10(19),22-ergostatetraen-3-ol (5Z,7e,22e)-(3S)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol 22-Tetraen 3beta 9,10,Secoergosta-5,7,10(19)-ol 31316-19-5 4-Methylene-3-[2-[tetrahydro-7a-methyl-1-(1,4,5-trimethyl-2-hexenyl)-4(3aH)-indanylidene]ethylidene]-Cyclohexanol 47768_SUPELCO 50-14-6 7489-18-1 7E677DC1-E1C4-4FC5-8F4A-BCE1857F7E87 8017-28-5 9,10,Secoergosta-5,7,10(19),22-tetraen 3.beta.-ol 9,10-Seco(5Z,7E,22E)-5,7,10(19),22-ergostatetraen-3-ol 9,10-Secoergosta-5,7,10(19),22-tetraen-3-beta-ol 9,10-Secoergosta-5,7,10(19),22-tetraen-3b-ol 95220_FLUKA 95220_SIGMA AC-1355 AC1L1FIE AC1NQXLH AC1NS4DE AC1NS9GI AC1NSSVD AC1NWAM3 AC1O5EDK AC1O6WAM ACon1_002187 Activated ergosterol BPBio1_000418 BSPBio_000380 BSPBio_001974 Buco-D C05441 C28H44O CALCIFEROL IN A GELATIN MATRIX CALCIFEROL, U.S.P. CHEBI:28934 CHEMBL1536 CID11003810 CID3249 CID5280793 CID5315257 CID5353610 CID5356615 CID5702050 CID6432478 CID6536972 Calciferol Calciferol (TN) Calciferol (vitamin D2) Calciferolum Calciferon 2 Condacaps Condocaps Condol Crtron Crystallina D-Arthin D-Tracetten D00187 DB00153 Daral Davitamon D Davitin De-rat concentrate Decaps Dee-Osterol Dee-Ron Dee-Ronal Dee-Roual Deltalin Deratol Detalup Diactol Divit urto Doral Drisdol Drisdol (TN) E5750_SIGMA EINECS 200-014-9 Ercalciol Ergocalciferol Ergocalciferol (D2) Ergocalciferol (JP15/USP) Ergocalciferol [INN:BAN:JAN] Ergocalciferol oil Ergocalciferol: Vitamin D | Ergocalciferolo Ergocalciferolo [DCIT] Ergocalciferols Ergocalciferolum Ergocalciferolum [INN-Latin] Ergorone Ergosterol activated Ergosterol irradiated Ergosterol, irradiated Ertron Fortodyl Geltabs Geltabs Vitamin D HMS1920K20 HMS2091B19 HMS502I07 HSDB 819 Haliver Hi-Deratol Hyperkil I05-0022 IDI1_000805 Infron Irradiated ergosta-5,7,22-trien-3-beta-ol Irradiated ergosta-5,7,22-trien-3.beta.-ol Irradiated ergosta-5,7,22-trien-3beta-ol Irradiated ergosterol LMST03010001 LMST03010014 LS-3228 MEGxm0_000466 MLS001332467 MLS001332468 Metadee Mina D2 MolPort-001-740-057 MolPort-001-793-930 MolPort-002-526-645 MolPort-003-666-178 MolPort-006-822-629 Mulsiferol Mykostin NCGC00142497-01 NCGC00179579-01 NCGC00179579-02 NSC 62792 NSC62792 Novovitamin-D Oleovitamin D Oleovitamin D, Synthetic Oleovitamin D2 Osteil Ostelin Prestwick3_000420 Prestwick_554 Radiostol Radstein Radsterin Rodine C Rodinec SMR000857106 SPECTRUM1500276 ST057150 STOCK1N-53397 Shock-ferol Shock-ferol sterogyl Sorex C.R Sorex C.R. Spectrum5_000666 Sterogyl Synthetic Vitamin D UNII-VS041H42XC Uvesterol D Uvesterol-D VITAMIN D2 VITAMIN D2 WATER DISPERSABLE U.S.P. VITAMIN_D2 Vigantol Vio D Vio-D Viostdrol Viosterol Viosterol in Oil Vitamin D2 Vitamin- D2 Vitamin-?D2 Vitamina D2 Vitavel-D WLN: L56 FYTJ A1 BY1&1U1Y1&Y1&1 FU2U- BL6YYTJ AU1 DQ ZINC04474571 ZINC04629876 beta-Ol bmse000510 component of Geltabs Vitamin D delta-Arthin delta-Tracetten ergocalciferol vitamin d-2 | |
| | 2 | | Cholecalciferol | approved, nutraceutical | Phase 4 | 875 | 67-97-0 | 6221, 10883523, 5280795 | ()-Vitamin D3 (+)-Vitamin D3 (+)-vitamin D3 (1S,3Z)-3-[(2e)-2-[(1R,3AR,7as)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-ol (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol (3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol (3beta,Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol (3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol (5E,7E)-9,10-Secocholesta-5,7,10-trien-3-ol (5Z,7E)-(3S)-9,10-seco-5,7,10(19)-cholestatrien-3-ol (5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol 1406-16-2 25(OH)D 3-beta,Z,7E-9,10-Secocholestr-5,7,10(19)-trien-3-ol 47763_SUPELCO 57651-82-8 67-97-0 7-Dehydrocholesterol activated 7-Dehydrocholesterol, Activated 7-Dehydrocholesterol, irradiated 7-Dehydrocholestrol, activated 8024-19-9 8050-67-7 89193_FLUKA 9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3-ol 9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3beta-ol 9,10-Secocholesta-5(Z),7(E),10(19)-trien-3(.beta.)-ol 9,10-Secocholesta-5,7,10(19)-trien-3-beta-ol 9,10-Secocholesta-5,7,10(19)-trien-3-ol 9,10-Secocholesta-5,7,10-trien-3-ol AB1002422 AC-11697 AC1L1ECK AC1L1M23 AC1LU7IZ AC1NQXLN AC1NR2UO AC1NR2UR AC1NR2UU AC1NS4AJ AC1NSHJX AC1O5EOF AC1O7GAV AC1O7GQ3 AC1O8FEU AC1O8PWJ AC1OF2GI AC1OF2GL AC1OIEW5 AC1OIEWB ACon1_001997 Activated 7-dehydrocholesterol Arachitol BPBio1_000460 BSPBio_000418 BSPBio_002408 Bio-0845 C05443 C1357_SIAL C27H44O C9756_SIGMA C9774_SIAL CAS-67-97-0 CC CCRIS 5813 CCRIS 6286 CHEBI:283119 CHEBI:28940 CHEMBL1042 CHEMBL432780 CID10000117 CID10045875 CID10340013 CID10883523 CID10894379 CID11014566 CID11025493 CID11058152 CID11463269 CID1548921 CID2735 CID5280795 CID5283710 CID5283711 CID5283712 CID5353527 CID5363362 CID6221 CID6432644 CID6604201 CID6604662 CID6708595 CID6713938 CID6992015 CID6992016 CID7067439 CID7067440 CID7251172 CID7251174 CID9821465 Calciol Cholecalciferol Cholecalciferol (D3) Cholecalciferol (JP15/USP) Cholecalciferol D3 Cholecalciferol [USAN:BAN:JAN] Cholecalciferol, D3 Cholecalciferolum Colecalciferol | Colecalciferol (INN) Colecalciferolo Colecalciferolo [DCIT] Colecalciferolum Colecalciferolum [INN-Latin] Colecalcipherol D00188 D3-Vicotrat D3-Vigantol DB00169 Delsterol Delta-D Delta-D (TN) Deparal Devaron DivK1c_006276 Duphafral D3 1000 EINECS 200-673-2 EINECS 215-797-2 EPA Pesticide Chemical Code 202901 Ebivit FeraCol Granuvit D3 HMS1569E20 HMS2092M12 HSDB 820 I05-0041 Irradiated 7-dehydrocholesterol KBio1_001220 KBio2_001643 KBio2_004211 KBio2_006779 KBio3_001628 KBioGR_001602 KBioSS_001643 LMST03020001 LMST03020219 LMST03020220 LMST03020221 LS-1570 LS-825 LT00244775 MEGxm0_000458 Micro-dee MolPort-001-740-051 MolPort-001-785-972 MolPort-003-666-021 MolPort-004-946-964 NCGC00016301-01 NCGC00017328-01 NCGC00091072-01 NCGC00142511-01 NCGC00159331-02 NCGC00159331-04 NCGC00178668-01 NCGC00179565-01 NCGC00179565-02 NEO Dohyfral D3 NSC 375571 NSC-375571 NSC375571 Oleovitamin D3 Prestwick0_000429 Prestwick1_000429 Prestwick2_000429 Prestwick3_000429 Prestwick_63 Provitamine Provitina Quintox Rampage Ricketon SMP1_000068 SPBio_001298 SPBio_002357 SR-05000001559 SR-05000001559-3 ST057172 SpecPlus_000180 Spectrum2_001369 Spectrum3_000764 Spectrum4_001201 Spectrum_001163 TNP00266 Trivitan UNII-1C6V77QF41 UPCMLD-DP152 UPCMLD-DP152:001 VITAMIN D VITAMIN D3 POWDER VITAMIN_D3 Vi-De3 Vi-de-3-hydrosol VidDe-3-hydrosol Videkhol Vigantol Vigorsan Vitamin D-3 Vitamin D3 Vitamin D3 emulsifiable Vitinc Dan-Dee-3 ZINC04474460 ZINC04492874 ZINC04492875 ZINC04492876 ZINC04492878 bmse000507 cholecalciferol colecalciferolum vitamin d-3 | |
| | 3 | | vitamin d | | Phase 4 | 1724 | | | | 4 | | Vitamins | | Phase 4 | 5282 | | | | 5 | | Bone Density Conservation Agents | | Phase 4 | 3376 | | | | 6 | | Trace Elements | | Phase 4 | 6001 | | | | 7 | | Ergocalciferols | | Phase 4 | 1281 | | | | 8 | | Micronutrients | | Phase 4 | 6001 | | | | 9 | | Calciferol | Nutraceutical | Phase 4 | 1383 | | | | 10 | | Vitamin D2 | Nutraceutical | Phase 4 | 1281 | | | | 11 | | Immunoglobulins | | Phase 1 | 6394 | | | | 12 | | Antibodies, Monoclonal | | Phase 1 | 4039 | | | | 13 | | Antibodies | | Phase 1 | 6394 | | | | 14 | | Menthol | approved | | 2606 | 2216-51-5 | 16666 | (− ()-Menthol (+)-Neo-menthol (+)-p-Menthan-3-ol (+-)-(1R*,3R*,4S*)-Menthol (+-)-Menthol (+/-)-Menthol (+/-)-p-Menthan-3-ol (-)-(1R,3R,4S)-Menthol (-)-Menthyl alcohol (-)-menthol (-)-p-Menthan-3-ol (-)-trans-p-Menthan-cis-ol (1R)-(-)-Menthol (1R,2S,5R)-(-)-menthol (1R,2S,5R)-Menthol (1R,3R,4S)-(-)-MENTHOL (1R,3R,4S)-(-)-Menthol (1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol (1S, 2S, 5R)-(+)-Neomenthol (1S,2R,5R)-(+)-Isomenthol (1S,2R,5S)-(+)-Menthol (1S,2R,5S)-Menthol (1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol (1r,2s,5r)-(-)-menthol (L)-MENTHOL (R)-(-)-Menthol (r)-(-)-menthol )-Menthol --MENTHOL 1-Menthol 1490-04-6 15356-60-2 15356-70-4 15785_RIEDEL 15785_SIAL 19863P 2-Isopropyl-5-methylcyclohexanol 20747-49-3 2216-51-5 3-p-Menthol 4-Isopropyl-1-methylcyclohexan-3-ol 491-02-1 5-Methyl-2-(1-methylethyl)-cyclohexanol 5-Methyl-2-(1-methylethyl)cyclohexanol 5-methyl-2-(propan-2-yl)cyclohexanol 5-methyl-2-propan-2-ylcyclohexan-1-ol 551376_ALDRICH 551376_FLUKA 588733_ALDRICH 613290_ALDRICH 613290_FLUKA 63660_FLUKA 63670_ALDRICH 63670_FLUKA 63975-60-0 6C6A4A8C-A054-468C-A1F0-F29E39838CF2 89-78-1 98167-53-4 AC1L1B2E AC1L28FR AC1Q1NQ2 AC1Q2QQM AI3-08161 AI3-52408 AKOS000119740 AR-1J3337 BB_NC-0057 BRN 1902288 BRN 3194263 BSPBio_003062 C00400 C10H20O CCRIS 3728 CCRIS 375 CCRIS 4666 CCRIS 9231 CHEBI:15409 CHEBI:545611 CHEMBL256087 CHEMBL470670 CID1254 CID16666 Caswell No. 540 D-(-)-Menthol D-p-Menthan-3-ol D00064 D008610 D04849 D04918 DB00825 DivK1c_000820 EINECS 201-939-0 EINECS 207-724-8 EINECS 216-074-4 EINECS 218-690-9 EINECS 239-387-8 EINECS 239-388-3 EPA Pesticide Chemical Code 051601 FEMA No. 2665 Fisherman's friend lozenges Fisherman's friend lozenges (TN) HMS1922G13 HMS2092L14 HMS502I22 | HSDB 5662 HSDB 593 Headache crystals Hexahydrothymol I06-1216 I14-7371 IDI1_000820 KBio1_000820 KBio2_000785 KBio2_003353 KBio2_005921 KBio3_002562 KBioSS_000785 L-(-)-Menthol L-(-)-menthol L-Menthol L-menthol LMPR0102090001 LS-2353 LS-57201 LS-886 LS-89531 LS-89533 Levomenthol Levomenthol [INN:BAN] Levomentholum Levomentholum [INN-Latin] Levomentol M0321 M0545 M2772_SIAL MENTHOL MLS002207256 Menthacamphor Menthol Menthol (USP) Menthol (VAN) Menthol natural Menthol natural, brazilian Menthol racemic Menthol racemique Menthol racemique [French] Menthol solution Menthol, (1alpha,2beta,5alpha)-Isomer Menthomenthol Menthyl alcohol MolPort-000-849-729 MolPort-001-793-392 NCGC00159382-02 NCGC00159382-03 NCGC00164247-01 NCGC00164247-02 NCI-C50000 NINDS_000820 NOOLISFMXDJSKH-KXUCPTDWBX NSC 2603 NSC 62788 NSC2603 NSC62788 Neoisomenthol Peppermint camphor RACEMIC MENTHOL U.S.P. Racementhol Racementhol [INN:BAN] Racementholum Racementholum [INN-Latin] Racementol Racementol [INN-Spanish] Racemic menthol Robitussin Cough Drops SDCCGMLS-0066659.P001 SMR001306785 SPBio_000869 SPECTRUM1503134 STK802468 Spectrum2_000855 Spectrum3_001561 Spectrum5_001060 Spectrum_000305 Tra-kill tracheal mite killer U.S.P. Menthol U.S.p. Menthol UNII-BZ1R15MTK7 UNII-L7T10EIP3A UNII-YS08XHA860 W266507_ALDRICH W266523_ALDRICH W266590_ALDRICH WLN: L6TJ AY1&1 BQ D1 WLN: L6TJ AY1&1 DQ D1 -L ZINC01482164 cis-1 ,3-trans-1,4-(+-)-menthol cis-1,3-trans-1,4-(+-)-menthol d,l-Menthol d-Menthol d-Neomenthol dl-3-p-Menthanol dl-Menthol dl-Menthol (JP15) l-(-)-Menthol l-Menthol l-Menthol (JP15) l-Menthol (TN) l-Menthol (natural) nchembio862-comp1 p-Menthan-3-ol rac-Menthol |
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Interventional clinical trials:| id | Name | Status | NCT ID | Phase |
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| 1 | Effect of High-Dose Vitamin D on Bone Density in Osteogenesis Imperfecta | Completed | NCT01713231 | Phase 4 | | 2 | Safety of Fresolimumab in the Treatment of Osteogenesis Imperfecta | Not yet recruiting | NCT03064074 | Phase 1 | | 3 | Whole Body Vibration Training in Children With Osteogenesis Imperfecta and Limited Mobility | Completed | NCT03029312 | |
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