MCID: HST016
MIFTS: 40

Histiocytic Sarcoma malady

Categories: Cancer diseases, Blood diseases, Rare diseases

Aliases & Classifications for Histiocytic Sarcoma

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Sources:
30ICD10, 31ICD10 via Orphanet, 40MESH via Orphanet, 54Orphanet, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Histiocytic Sarcoma:

Name: Histiocytic Sarcoma 54 68

Characteristics:

Orphanet epidemiological data:

54
histiocytic sarcoma:
Age of onset: Adult

Classifications:



External Ids:

Orphanet54 ORPHA86896
MESH via Orphanet40 D054747
UMLS via Orphanet69 C0334663
ICD10 via Orphanet31 C96.8
ICD1030 C96.8

Summaries for Histiocytic Sarcoma

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Wikipedia:71 Histiocytic sarcoma is a tumor derived from histiocytes. The tumor is often positive for CD163 and can... more...

MalaCards based summary: Histiocytic Sarcoma is related to malignant histiocytosis and reticulosarcoma. An important gene associated with Histiocytic Sarcoma is CD163 (CD163 Molecule), and among its related pathways are Advanced glycosylation endproduct receptor signaling and Senescence and Autophagy in Cancer. Affiliated tissues include brain, thyroid and spleen, and related mouse phenotypes are cellular and hematopoietic system.

Related Diseases for Histiocytic Sarcoma

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Diseases related to Histiocytic Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 116)
idRelated DiseaseScoreTop Affiliating Genes
1malignant histiocytosis11.4
2reticulosarcoma10.9
3sarcoma10.8
4lucey-driscoll syndrome10.3MUC1, S100B
5secondary pulmonary hemosiderosis10.3MUC1, S100B
6lupus - neurological sequelae10.3PTEN, S100B
7myelinoclastic diffuse sclerosis10.3MUC1, S100B
8invasive mole10.3MUC1, S100B
9bronchial mucus gland adenoma10.3PTEN, S100B
10myoma10.3MUC1, S100B
11pemphigus vegetans10.3MUC1, S100B
12spleen angiosarcoma10.3MUC1, S100B
13immunodeficiency due to a classical component pathway complement deficiency10.3CDKN2A, MUC1
14ovarian cystadenoma10.3MUC1, S100B
15trombiculiasis10.3MUC1, S100B
16aneurysm of sinus of valsalva10.2MUC1, PTEN, S100B
17lower clivus meningioma10.2CR1, CR2
18mediastinum liposarcoma10.2CDKN2A, MUC1, S100B
19polydactyly cleft lip palate psychomotor retardation10.2CDKN2A, MS4A1, MUC1
20pathologic nystagmus10.2CDKN2A, MUC1, S100B
21spondylarthropathy10.2BRAF, CDKN2A
22lymphoma10.2
23alezzandrini syndrome10.2LGALS3, MS4A1
24postgerminal center chronic lymphocytic leukemia/small lymphocytic lymphoma10.2MUC1, S100B
25biliary papillomatosis10.2BRAF, MUC1, S100B
26occlusion precerebral artery10.2CDKN2A, MUC1, S100B
27cutis laxa10.2CD163, CSF1, CSF1R
28leukemia10.2
29autosomal recessive stickler syndrome10.2BRAF, MUC1
30mite infestation10.2CD163, CR1, CR2
31trachea squamous cell carcinoma10.2CDKN2A, MUC1, PTEN
32microinvasive cervical squamous cell carcinoma10.2MUC1, S100B
33acute disseminated encephalomyelitis10.2BRAF, CDKN2A, PTEN
34adenosquamous colon carcinoma10.2CD163, CR1, CR2
35cavernous sinus meningioma10.2CD163, FSCN1, S100B
36popliteal pterygium syndrome, bartsocas-papas type10.2LGALS3, MUC1, S100B
37chiasmal syndrome10.2CD68, S100B
38heart sarcoma10.2CD68, CDKN2A
39omodysplasia 210.2CR1, CR2, MUC1
40cecum adenoma10.1CR1, CR2, S100B
41intestinal benign neoplasm10.1LGALS3, MUC1, PTEN
42demyelinating disease10.1CD68, PTEN
43ulnar neuropathy10.1CD163, CD68, PTEN
44glomeruloid hemangioma10.1BRAF, CDKN2A, PTEN
45bilateral breast cancer10.1CD163, CD68, CR2
46teeth hard tissue disease10.1CD163, CD68
47dentin dysplasia with sclerotic bones10.1BRAF, CD163, CSF1, S100B
48cloacogenic carcinoma10.1CR1, CR2
49episodic ataxia10.1CD68, CDKN2A, MUC1
50lymphoblastic leukemia10.1

Graphical network of the top 20 diseases related to Histiocytic Sarcoma:



Diseases related to histiocytic sarcoma

Symptoms & Phenotypes for Histiocytic Sarcoma

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MGI Mouse Phenotypes related to Histiocytic Sarcoma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053847.4BRAF, CD163, CDKN2A, CSF1, CSF1R, FSCN1
2MP:00053976.8BRAF, CD163, CD68, CDKN2A, CR2, CSF1
3MP:00053875.5BRAF, CD163, CD68, CDKN2A, CR2, CSF1

Drugs & Therapeutics for Histiocytic Sarcoma

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Drugs for Histiocytic Sarcoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 20)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
LenalidomideapprovedPhase 2736191732-72-6216326
Synonyms:
1-oxo-2-(2,6-Dioxopiperidin-3-yl)-4-aminoisoindoline
191732-72-6
3-(4-Amino-1-oxo-1,3-dihydro-2H-isoindol-2-yl)piperidine-2,6-dione
3-(4-Amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione
3-(7-Amino-3-oxo-1H-isoindol-2-yl)-piperidine-2,6-dione
3-(7-amino-3-oxo-1H-isoindol-2-yl)piperidine-2,6-dione
346670-73-3
443912-14-9
AC-914
AC1L50II
AKOS005146276
ALBB-015321
Bio-0168
C467567
CC 5013
CC-5013
CC-5013, Revlimid, Lenalidomide
CC5013
CDC 501
CDC-501
CDC-5013
CHEMBL848
CID216326
Celgene brand of lenalidomide
D04687
 
DB00480
EC-000.2340
ENMD-0997
I06-0831
IMID-1
IMID-5013
IMiD3
IMiD3 cpd
IMid-1
LS-184040
Lenalidomide
Lenalidomide (USAN/INN)
Lenalidomide [USAN]
MolPort-003-848-370
NCGC00167491-01
NSC747972
Revamid
Revimid
Revlimid
Revlimid (Celgene)
Revlimid (TN)
S1029_Selleck
STK639603
Thalidomide analog CC-5013
UNII-F0P408N6V4
lenalidomide
2
EverolimusapprovedPhase 21940159351-69-66442177
Synonyms:
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-Dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.04,9)hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentaone
(1R,9S,12S,15R,16E,23S,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo(30.3.1.0(sup 4,9))hexatriacont
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3H-23,27-epoxypyrido[2,1-c][1,4]oxazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34as)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-6,8,12,14,20,26-hexamethy
07741_FLUKA
159351-69-6
40-O-(2-hydroxyethyl)-rapamycin
42-O-(2-Hydroxyethyl)rapamycin
Afinitor
CERTICAN(R)
CHEMBL1201755
Certican
D02714
DB01590
 
Everolimus
Everolimus (JAN/USAN/INN)
Everolimus [USAN]
LS-143292
MolPort-003-847-342
MolPort-003-925-588
NCGC00167512-01
NVP-RAD-001
RAD 001
RAD-001
RAD-001C
RAD001
RAD001, SDZ-RAD, Certican, Zortress, Afinitor, Everolimus
S1120_Selleck
SDZ-RAD
UNII-9HW64Q8G6G
Zortress
everolimus
3
Sirolimusapproved, investigationalPhase 2194053123-88-95284616, 6436030, 46835353
Synonyms:
(-)-Rapamycin
(-)-rapamycin
1fkb
1pbk
23,27-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine
23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine
23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29
3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone
53123-88-9
A422989, NSC226080
AC-722
AC1L1JH9
AC1L7MJ9
AC1L9ZMV
AY 22989
AY-22989
AY22989
Ambotz53123-88-9
Antibiotic AY 22989
BIDD:PXR0165
Bio1_000293
Bio1_000782
Bio1_001271
Bio2_000375
Bio2_000855
BiomolKI2_000084
C07909
C51H79NO13
CBiol_002007
CCRIS 9024
CHEBI:100923
CHEBI:9168
CHEMBL413
CID10213190
CID10795871
CID11949238
CID11959112
CID313006
CID478951
CID5040
CID5284616
CID5358081
CID5374464
CID5460439
CID5497196
CID5924240
CID6436030
CID6610270
CID6610346
CID6711160
CID6713081
CID9833581
CID9854379
CID9854380
CID9962926
CID9962928
D00753
DB00877
DE-109
DivK1c_006936
 
FT-0082351
HMS2089A21
HSDB 7284
KBio1_001880
KBio2_000410
KBio2_002978
KBio2_005546
KBio3_000779
KBio3_000780
KBioGR_000410
KBioSS_000410
LCP-Siro
LMPK06000003
LS-143290
MLS000028373
MS-R001
MolMap_000043
MolPort-003-959-433
NCGC00021305-05
NCI60_001851
NCIMech_000355
NSC 226080
NSC226080
Perceiva
QTL1_000069
R0395_SIAL
R0395_SIGMA
RAP
RAPA
RPM
Rapammune
Rapamune
Rapamune (TN)
Rapamycin
Rapamycin (TN)
Rapamycin C-7, analog 4
Rapamycin Immunosuppressant Drug
Rapamycin from Streptomyces hygroscopicus
S1039_Selleck
SIIA 9268A
SILA 9268A
SILA9268A
SMP1_000255
SMR000058564
Sirolimus
Sirolimus (RAPAMUNE)
Sirolimus (USAN/INN)
Sirolimus [USAN:BAN:INN]
Sirolimus, Rapamune,Rapamycin
SpecPlus_000840
UNII-W36ZG6FT64
UNM-0000358684
WY-090217
Wy 090217
heptadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy
nchembio.100-comp4
nchembio.2007.42-comp2
nchembio.79-comp1
nchembio762-comp1
nchembio883-comp3
rapamycin
sirolimus
4
OlaparibapprovedPhase 2140763113-22-023725625
Synonyms:
4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one
4-[(3-{[4-Cyclopropylcarbonyl)piperazin-4-yl]carbonyl}-4-fluorophenyl)methyl]phtalazin-1(2H)-one
4-[3-(4-Cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one
763113-22-0
937799-91-2
AKOS005145764
AZD 2281
AZD-2281
AZD2281
 
Acylpiperazine analogue, 47
CHEMBL521686
EC-000.2324
EN002690
FT-0083489
KU-0059436
KU-59436
Olaparib
Olaparib, KU-0059436, AZD2281, KU0059436, AZD2281
S1060_Selleck
olaparib
5
Miconazoleapproved, investigational, vet_approvedPhase 2370622916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
6Anti-Infective AgentsPhase 222062
7Anti-Bacterial AgentsPhase 211226
8Immunosuppressive AgentsPhase 213086
9Angiogenesis InhibitorsPhase 24257
10Angiogenesis Modulating AgentsPhase 24185
11Antifungal AgentsPhase 23696
12Antibiotics, AntitubercularPhase 27180
13Poly(ADP-ribose) Polymerase InhibitorsPhase 2340
14
Zidovudineapproved49530516-87-135370
Synonyms:
-Azido-3&prime
-deoxythymidine
1-(3-Azido-2,3-dideoxy-beta-D-ribofuranosyl)thymine
3&prime
3' Azido 2',3' Dideoxythymidine
3' Azido 3' deoxythymidine
3'-Azido-2',3'-Dideoxythymidine
3'-Azido-3'-deoxythymidine
3'-Azido-3'-deoxythymidine & Concanavalin A
3'-Azido-3'-deoxythymidine & Erythropoietin
3'-Azido-3'-deoxythymidine & Heteropolyoxotungstate PM-19
3'-Azido-3'-deoxythymidine & Interleukin-1
3'-Azido-3'-deoxythymidine & Interleukin-2
3'-Azido-3'-deoxythymidine & Interleukin-6
3'-Azido-3'-deoxythymidine & Lithium & Erythropoietin
3'-Azido-3'-deoxythymidine & Lithium & Interleukin-1
3'-Azido-3'-deoxythymidine & Lithium & Interleukin-6
3'-Azido-3'-deoxythymidine & Lymphoblastoid Interferon
3'-Azido-3'-deoxythymidine & Sho-Saiko-To
3'-Azido-3'-deoxythymidine (AIDS)
3'-Azido-3'deoxythymidine & Interferon .alpha.
3'-Azidothymidine
3'-Deoxy-3'-azidothymidine
3'-azido-3'-deoxythymidine, AZT
3-Azido-3-deoxythymidine
30516-87-1
399024-19-2
A2169_SIGMA
AC1L1TKL
AC1Q2OEK
AZT
AZT & CD4(178)-PE 40
AZT & Colony-stimulating factor 2
AZT & Concanavalin A (ConA)
AZT & EPO
AZT & GM-CSF
AZT & HPA
AZT & IFN.alpha.
AZT & IL-1
AZT & IL-2
AZT & IL-6
AZT & Interferon-.alpha.-2
AZT & Li & EPO
AZT & Li & GM-CSF
AZT & Li & IL-1
AZT & Li & IL-6
AZT & Lymphoblastoid Interferon
AZT & NP (from PHCA or HSA)
AZT & PM-19
AZT & SST
AZT & rIFN.alpha.2
AZT & rsCD4 & rIFN.alpha.A
AZT & rsT4
AZT & sCD4
AZT & srCD4
AZT (Antiviral)
AZT Antiviral
AZT TRANSPLACENTAL CARCINOGENESIS STUDY
AZT+PRO 140
AZT, Antiviral
Antiviral AZT
Apo-Zidovudine
Azidothymidine
Aztec
BB_NC-1012
BPBio1_000403
BRD-K72903603-001-04-6
BSPBio_000365
BSPBio_003153
BW A509U
BW-A 509U
BW-A-509U
BW-A509U
BWA 509U
BWA-509U
BWA509U
C07210
CCRIS 105
CHEBI:10110
CHEBI:127307
CHEMBL129
CID35370
 
CPD000058351
Compound S
Cpd S
D00413
D015215
DB00495
DRG-0004
DS-4152 & AZT
DivK1c_000524
HMS1921J20
HMS2090G11
HMS2092D06
HMS501K06
HSDB 6515
IDI1_000524
Interferon AD + 3'-azido-3'-deoxythymidine
Intron A & AZT
K7 [P Ti2 W10 O40]
KBio1_000524
KBio2_001828
KBio2_004396
KBio2_006964
KBio3_002653
KBioGR_000703
KBioSS_001828
LS-1159
Liposomal AZT-SN-1
Liposomal AZT-SN-3
MLS000028548
MLS001055351
MLS001076358
MLS002153202
MLS002222249
Met-SDF-1.beta. & AZT
Met-SDF-1.beta. & Zidovudine
MolPort-002-507-286
NCGC00023945-03
NCGC00023945-04
NCGC00023945-05
NCGC00023945-08
NCGC00178237-01
NCGC00178237-02
NINDS_000524
NSC 602670
Novo-Azt
PC-SOD+AZT
Prestwick3_000333
Propolis+AZT
Racemic Liposomal AZT
Retrovir
Retrovir (TN)
Retrovir(TM)
SAM002548971
SMR000058351
SN-1-dipalmitoylglycerophospho-AZT (in a lipid vesicle)
SN-3-dipalmitoylglycerophospho-AZT (in a lipid vesicle)
SPBio_000834
SPECTRUM1502109
STK801891
Spectrum2_000927
Spectrum3_001507
Spectrum4_000332
Spectrum5_001101
Spectrum_001348
UNII-4B9XT59T7S
ZDV
ZIDOVUDINE [AZT]
ZINC03779042
ZVD
Zidovudin
Zidovudina
Zidovudina [Spanish]
Zidovudine (JAN/USP/INN)
Zidovudine EP III
Zidovudine [USAN:INN:BAN:JAN]
Zidovudine+PRO 140
Zidovudinum
Zidovudinum [Latin]
antiviral
azidodeoxythymidine
rIFN-beta seron & AZT
racemic-dipalmitoylglycerophospho-AZT (in a lipid vesicle)
zidovudin
zidovudine
15Reverse Transcriptase Inhibitors1913
16Nucleic Acid Synthesis Inhibitors4962
17Antimetabolites12054
18Anti-HIV Agents3162
19Anti-Retroviral Agents3296
20Antiviral Agents9967

Interventional clinical trials:

idNameStatusNCT IDPhase
1A Study of Lenalidomide for Adult Histiocyte DisordersRecruitingNCT02523040Phase 2
2Pediatric MATCH: Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Advanced Refractory Solid Tumors or LymphomasNot yet recruitingNCT03155620Phase 2
3A Study of Azidothymidine (AZT) in the Treatment of HIV Infection in Patients Receiving a Bone Marrow TransplantCompletedNCT00002284

Search NIH Clinical Center for Histiocytic Sarcoma

Genetic Tests for Histiocytic Sarcoma

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Anatomical Context for Histiocytic Sarcoma

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MalaCards organs/tissues related to Histiocytic Sarcoma:

36
Brain, Thyroid, Spleen, B cells, Bone marrow, Lymph node, Bone

Publications for Histiocytic Sarcoma

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Articles related to Histiocytic Sarcoma:

(show top 50)    (show all 265)
idTitleAuthorsYear
1
Dermoscopic characteristics of a cutaneous histiocytic sarcoma in a young patient. (28087030)
2017
2
Histiocytic Sarcoma Associated with Coombs Negative Acute Hemolytic Anemia: A Rare Presentation. (27429816)
2016
3
Histological and immunohistochemical features of histiocytic sarcoma in four domestic ferrets (Mustela putorius furo). (26965237)
2016
4
Risk Factors Associated with Development of Histiocytic Sarcoma in Bernese Mountain Dogs. (27160025)
2016
5
Evaluation of Costimulatory Molecules in Peripheral Blood Lymphocytes of Canine Patients with Histiocytic Sarcoma. (26901565)
2016
6
A rare case of paediatric histiocytic sarcoma of the maxilla and mandible. (27090951)
2016
7
Hepatic Involvement of Histiocytic Sarcoma: CT and MRI Findings. (27587965)
2016
8
Histiocytic sarcoma: secondary neoplasm or "transdifferentiation" in the setting of B-acute lymphoblastic leukemia. (27856472)
2016
9
High-dose methotrexate-based chemotherapy as treatment for histiocytic sarcoma of the central nervous system. (26727454)
2016
10
SYSTEMIC HISTIOCYTIC SARCOMA IN A COMMON HIPPOPOTAMUS (HIPPOPOTAMUS AMPHIBIUS). (27468044)
2016
11
Disseminated histiocytic sarcoma in a child: a clinicopathological dichotomy with 8a88years survival. (27190112)
2016
12
Cooperation of BRAF(F595L) and mutant HRAS in histiocytic sarcoma provides new insights into oncogenic BRAF signaling. (26582644)
2016
13
Clinical prognostic factors in canine histiocytic sarcoma. (27334037)
2016
14
Primary Orbital Histiocytic Sarcoma in a Child Successfully Treated With Multiagent Chemotherapy. (27467374)
2016
15
An unusual case of chronic meningitis due to histiocytic sarcoma of the central nervous system with meningeal dissemination. (27325388)
2016
16
NLRX1 suppresses tumorigenesis and attenuates histiocytic sarcoma through the negative regulation of NF-I_B signaling. (27105514)
2016
17
Cutaneous Histiocytic Sarcoma with Regional Lymph Node Metastasis in a Netherland Dwarf Rabbit (Oryctolagus cuniculus). (27890406)
2016
18
Microglioma in a child - a further case in support of the microglioma entity and distinction from histiocytic sarcoma. (27191913)
2016
19
Gastric histiocytic sarcoma in a dog. (27925661)
2016
20
Reduced angiogenic gene expression in morbillivirus-triggered oncolysis in a translational model for histiocytic sarcoma. (27860224)
2016
21
Histiocytic Sarcoma as a Secondary Malignancy: Pathobiology, Diagnosis, and Treatment. (26990812)
2016
22
Long-term treatment with the oncolytic ECHO-7 virus Rigvir of a melanoma stage IV M1c patient, a small cell lung cancer stage IIIA patient, and a histiocytic sarcoma stage IV patient-three case reports. (27457663)
2016
23
Apoptosis inhibitor of macrophage (AIM) reduces cell number in canine histiocytic sarcoma cell lines. (27246397)
2016
24
Persistent Morbillivirus Infection Leads to Altered Cortactin Distribution in Histiocytic Sarcoma Cells with Decreased Cellular Migration Capacity. (27911942)
2016
25
Two cases of histiocytic sarcoma with BCL2 translocations and occult or subsequent follicular lymphoma. (27134111)
2016
26
Somatic mutations in histiocytic sarcoma identified by next generation sequencing. (27259537)
2016
27
Circulating let-7g is down-regulated in Bernese Mountain dogs with disseminated histiocytic sarcoma and carcinomasA -A a prospective study. (26792388)
2016
28
Diffuse Histiocytic Sarcoma Involving the Choroid. (27541306)
2016
29
Primary histiocytic sarcoma of the uterine cervix: an extremely rare entity. (27828780)
2016
30
Histiocytic Sarcoma in a Kidney Transplant Patient: A Case Report and Review of the Literature. (27795864)
2016
31
Comparison of conventional magnetic resonance imaging and nonenhanced three dimensional time-of-flight magnetic resonance angiography findings between dogs with meningioma and dogs with intracranial histiocytic sarcoma: 19 cases (2010-2014). (27135670)
2016
32
Disseminated Histiocytic Sarcoma in an African Hedgehog (Atelerix albiventris). (27720131)
2016
33
Sudden unexpected death from an undiagnosed histiocytic sarcoma in an adolescent female. (27465385)
2016
34
Diffuse leptomeningeal histiocytic sarcoma in the cerebrospinal fluid of 2 dogs. (26882507)
2016
35
A 43-Year-Old Female with Multifocal Cerebral Lesions. Histiocytic Sarcoma. (26086057)
2015
36
Post mortem computed tomography and core needle biopsy in comparison to autopsy in eleven Bernese mountain dogs with histiocytic sarcoma. (26329821)
2015
37
Flow cytometry used to identify histiocytic sarcoma: A case report. (26082038)
2015
38
A Case of G-CSF-Producing Histiocytic Sarcoma of the Stomach. (25785346)
2015
39
Histiocytic Sarcoma and Bilateral Facial Vein Thrombosis in a Siberian Hamster (Phodopus sungorus). (25926398)
2015
40
Cutaneous histiocytic sarcoma with E-cadherin expression in a Pembroke Welsh Corgi dog. (26330395)
2015
41
Histiocytic Sarcoma Originating in the Lung in a 16-Year-Old Male. (26106007)
2015
42
Pathology in Practice. Histiocytic sarcoma. (26133215)
2015
43
Influence of a survivin suppressor YM155 on the chemoresistance of canine histiocytic sarcoma cells. (26048444)
2015
44
Evaluation of a combination chemotherapy protocol including lomustine and doxorubicin in canine histiocytic sarcoma. (25828786)
2015
45
Sub-cutaneous histiocytic sarcoma in a child: a case report. (26757497)
2015
46
Fine needle aspiration cytology of histiocytic sarcoma with dendritic cell differentiation: a case of transdifferentiation from low-grade follicular lymphoma. (25993973)
2015
47
Coexistence of tuberculosis with histiocytic sarcoma: A rare association. (26458659)
2015
48
Histiocytic sarcoma; case report of a rare disease in a kidney transplant recipient. (26312238)
2015
49
An unusual case of histiocytic sarcoma. (27509705)
2015
50
Concomitant follicular lymphoma and histiocytic sarcoma: A rare progression, trans-differentiation or co-occurrence? (26549087)
2015

Variations for Histiocytic Sarcoma

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Expression for genes affiliated with Histiocytic Sarcoma

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Search GEO for disease gene expression data for Histiocytic Sarcoma.

Pathways for genes affiliated with Histiocytic Sarcoma

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GO Terms for genes affiliated with Histiocytic Sarcoma

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Cellular components related to Histiocytic Sarcoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1CSF1-CSF1R complexGO:199068210.6CSF1, CSF1R
2plasma membraneGO:00058866.7BRAF, CD163, CD68, CR1, CR2, CSF1

Biological processes related to Histiocytic Sarcoma according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1complement receptor mediated signaling pathwayGO:000243010.5CR1, CR2
2macrophage colony-stimulating factor signaling pathwayGO:003814510.4CSF1, CSF1R
3macrophage differentiationGO:003022510.4CSF1, CSF1R
4negative regulation of immunological synapse formationGO:200052110.4HAVCR2, LGALS3
5negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cellGO:200118910.4HAVCR2, LGALS3
6long-term synaptic potentiationGO:006029110.2BRAF, PTEN, S100B
7regulation of axon regenerationGO:00486799.8BRAF, PTEN
8cell proliferationGO:00082839.5CSF1, CSF1R, FSCN1, PTEN, S100B
9positive regulation of ERK1 and ERK2 cascadeGO:00703749.5BRAF, CSF1R, HAVCR2, PTEN
10immune system processGO:00023769.1CR1, CR2, CSF1, CSF1R, HAVCR2, LGALS3
11innate immune responseGO:00450878.8CR1, CR2, CSF1, CSF1R, HAVCR2, LGALS3

Sources for Histiocytic Sarcoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet