MCID: HST009
MIFTS: 47

Histiocytoma malady

Categories: Cancer diseases

Aliases & Classifications for Histiocytoma

Aliases & Descriptions for Histiocytoma:

Name: Histiocytoma 12 29 42 14 69
Cutaneous Fibrous Histiocytoma 69

Classifications:



External Ids:

Disease Ontology 12 DOID:4231
MeSH 42 D051642
NCIt 47 C35765
UMLS 69 C1509147

Summaries for Histiocytoma

MalaCards based summary : Histiocytoma, also known as cutaneous fibrous histiocytoma, is related to fibrosarcoma and osteomyelitis. An important gene associated with Histiocytoma is MFHAS1 (Malignant Fibrous Histiocytoma Amplified Sequence 1), and among its related pathways/superpathways are Glioma and Mitotic G1-G1/S phases. The drugs Doxorubicin and Ifosfamide have been mentioned in the context of this disorder. Affiliated tissues include bone, breast and lung, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and cardiovascular system

Wikipedia : 71 A histiocytoma is a tumour consisting of histiocytes. Histiocytes are cells that are a part of the... more...

Related Diseases for Histiocytoma

Diseases related to Histiocytoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 238)
id Related Disease Score Top Affiliating Genes
1 fibrosarcoma 29.8 EWSR1 KIT MYOD1
2 osteomyelitis 29.7 CDK4 MDM2
3 fibrous histiocytoma 12.3
4 diaphyseal medullary stenosis with malignant fibrous histiocytoma 12.3
5 histiocytoma, angiomatoid fibrous, somatic 12.1
6 cutaneous fibrous histiocytoma 12.0
7 malignant fibrous histiocytoma of bone 12.0
8 malignant skin fibrous histiocytoma 11.8
9 benign deep fibrous histiocytoma 11.8
10 undifferentiated pleomorphic sarcoma 11.7
11 generalized eruptive histiocytosis 11.7
12 sclerosing hemangioma 11.6
13 myxofibrosarcoma 11.5
14 malignant fibroxanthoma 11.3
15 tenosynovial giant cell tumor 10.9
16 urachal cancer 10.8
17 pigmented villonodular synovitis 10.7
18 reticulohistiocytic granuloma 10.7
19 oral erosive lichen 10.3 CD163 F13A1
20 bilateral multicystic dysplastic kidney 10.3 ATF1 CREB1 EWSR1
21 sarcoma 10.2
22 hurst hallam hockey syndrome 10.2 ATF1 CDK4 CREB1
23 blood protein disease 10.2 CDK4 MDM2 SERPINA3
24 primary eye hypotony 10.2 CDK4 MDM2
25 pinta disease 10.2 CDK4 FUS MDM2
26 liposarcoma of the ovary 10.1 CDK4 FUS MDM2
27 intrahepatic cholestasis 10.1 EWSR1 MDM2 MTAP
28 diarrhea, chronic, with villous atrophy 10.1 F13A1 KIT MDM2
29 bacterial vaginosis 10.1 EWSR1 MDM2
30 botryoid rhabdomyosarcoma 10.1 KIT MYOD1
31 extranodal nasal nk/t cell lymphoma 10.1 CDK4 EWSR1 KIT
32 childhood immature teratoma of ovary 10.1 CD163 CDK4 MDM2
33 mixed type rhabdomyosarcoma 10.1 MB MYOD1
34 acute mountain sickness 10.1 MDM2 TP53
35 extraosseous osteosarcoma 10.1 CDK4 MDM2 MYOD1
36 intrahepatic bile duct cystadenoma 10.1 MB MYOD1
37 glomus tumor 10.1 KIT MITF
38 malignant giant cell tumor of the tendon sheath 10.1 PTPRC SERPINA3
39 van regemorter pierquin vamos syndrome 10.1 KIT MB MDM2
40 rommen mueller sybert syndrome 10.0 CDK4 MDM2 TP53
41 multifocal osteogenic sarcoma 10.0 CDK4 KIT MDM2 SERPINA3
42 brain stem angioblastoma 10.0 CDK4 MDM2 TP53
43 aneurysm 10.0
44 interstitial lung disease 10.0 CDK4 MDM2 TP53
45 extraocular retinoblastoma 10.0 CDK4 MDM2 TP53
46 congenital muscular dystrophy with hyperlaxity 10.0 EWSR1 FUS PTPRC
47 intracranial liposarcoma 10.0 CDK4 FUS MB MDM2
48 amelogenesis imperfecta-gingival hyperplasia syndrome 10.0 CDK4 MDM2 MYOD1 SERPINA3
49 integumentary system benign neoplasm 10.0 CDK4 MDM2 TP53
50 post-surgical hypoinsulinemia 10.0 CDK4 MDM2 TP53

Graphical network of the top 20 diseases related to Histiocytoma:



Diseases related to Histiocytoma

Symptoms & Phenotypes for Histiocytoma

GenomeRNAi Phenotypes related to Histiocytoma according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-1 9.62 CD163
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-104 9.62 CD163
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-111 9.62 CD163
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-112 9.62 FUS
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-116 9.62 CDK4
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-134 9.62 CD163
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-184 9.62 CD163
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-203 9.62 EWSR1
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-216 9.62 EWSR1
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-40 9.62 FUS
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-53 9.62 CDK4 EWSR1
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-60 9.62 FUS
13 Decreased shRNA abundance (Z-score < -2) GR00366-A-77 9.62 CDK4 EWSR1 FUS CD163
14 Decreased shRNA abundance (Z-score < -2) GR00366-A-84 9.62 EWSR1
15 Decreased shRNA abundance (Z-score < -2) GR00366-A-89 9.62 EWSR1
16 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.62 CD163

MGI Mouse Phenotypes related to Histiocytoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.16 CD163 CDK4 CREB1 F13A1 KIT MB
2 homeostasis/metabolism MP:0005376 10.14 CD163 CDK4 CREB1 F13A1 KIT MB
3 endocrine/exocrine gland MP:0005379 10.03 CDK4 CREB1 F13A1 KIT MDM2 MITF
4 muscle MP:0005369 9.97 CD163 CDK4 CREB1 KIT MB MDM2
5 normal MP:0002873 9.86 MITF MYOD1 PTPRC TP53 CDK4 CREB1
6 neoplasm MP:0002006 9.8 CDK4 KIT MDM2 MYOD1 PTPRC TP53
7 reproductive system MP:0005389 9.56 CDK4 CREB1 F13A1 KIT MDM2 MITF
8 pigmentation MP:0001186 9.55 CDK4 KIT MDM2 MITF TP53
9 respiratory system MP:0005388 9.23 PTPRC TP53 CREB1 F13A1 KIT MB

Drugs & Therapeutics for Histiocytoma

Drugs for Histiocytoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 105)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Doxorubicin Approved, Investigational Phase 3,Phase 2,Phase 1 23214-92-8 31703
2
Ifosfamide Approved Phase 3,Phase 2,Phase 1 3778-73-2 3690
3
Mechlorethamine Approved Phase 3,Phase 2,Phase 1 51-75-2 4033
4
Carboplatin Approved Phase 3 41575-94-4 10339178 498142 38904
5
Cyclophosphamide Approved, Investigational Phase 3,Phase 2 50-18-0, 6055-19-2 2907
6
Dactinomycin Approved Phase 3 50-76-0 2019 457193
7
Epirubicin Approved Phase 3 56420-45-2 41867
8
Etoposide Approved Phase 3,Phase 2 33419-42-0 36462
9
Vincristine Approved, Investigational Phase 3 2068-78-2, 57-22-7 5978
10
Lenograstim Approved Phase 3,Phase 2 135968-09-1
11
Trabectedin Approved, Investigational Phase 2, Phase 3 114899-77-3 108150
12
Doxil Approved June 1999 Phase 3,Phase 2,Phase 1 31703
13 Alkylating Agents Phase 3,Phase 2,Phase 1
14 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1
15 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1
16 Antineoplastic Agents, Alkylating Phase 3,Phase 2,Phase 1
17 Isophosphamide mustard Phase 3,Phase 2,Phase 1
18 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1
19 Anti-Infective Agents Phase 3,Phase 2,Phase 1
20 Antimitotic Agents Phase 3,Phase 2,Phase 1
21 Antineoplastic Agents, Phytogenic Phase 3,Phase 2,Phase 1
22 Antirheumatic Agents Phase 3,Phase 2,Phase 1
23 Etoposide phosphate Phase 3,Phase 2
24 Immunosuppressive Agents Phase 3,Phase 2,Phase 1
25 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2
26
Indinavir Approved Phase 2 150378-17-9 5362440
27
Ritonavir Approved, Investigational Phase 2 155213-67-5 392622
28
Dacarbazine Approved, Investigational Phase 2 4342-03-4 5351166
29
Temozolomide Approved, Investigational Phase 2 85622-93-1 5394
30
Sunitinib Approved, Investigational Phase 2 341031-54-7, 557795-19-4 5329102
31
Bevacizumab Approved, Investigational Phase 2 216974-75-3
32
Gemcitabine Approved Phase 2,Phase 1 95058-81-4 60750
33
Sorafenib Approved, Investigational Phase 2 284461-73-0 216239 406563
34
Romidepsin Approved, Investigational Phase 2 128517-07-7 5352062
35
Everolimus Approved Phase 1, Phase 2 159351-69-6 6442177
36
Miconazole Approved, Investigational, Vet_approved Phase 1, Phase 2 22916-47-8 4189
37
Sirolimus Approved, Investigational Phase 1, Phase 2 53123-88-9 5284616 6436030 46835353
38
Paclitaxel Approved, Vet_approved Phase 1, Phase 2 33069-62-4 36314
39
Cisplatin Approved Phase 2 15663-27-1 84093 441203 2767
40
Methotrexate Approved Phase 2 1959-05-2, 59-05-2 126941
41
Pembrolizumab Approved Phase 1, Phase 2 1374853-91-4
42
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2 59-30-3 6037
43
Niacin Approved, Investigational, Nutraceutical Phase 2 59-67-6 938
44
Nicotinamide Approved, Nutraceutical Phase 2 98-92-0 936
45
leucovorin Approved, Nutraceutical Phase 2 58-05-9 54575, 6560146 143
46
Docetaxel Approved May 1996, Investigational Phase 2,Phase 1 114977-28-5 148124 9877265
47
Camptothecin Experimental Phase 2 7689-03-4
48 Anti-HIV Agents Phase 2
49 Anti-Retroviral Agents Phase 2
50 Antiviral Agents Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 62)
id Name Status NCT ID Phase
1 Ifosfamide and Doxorubicin, Radiation Therapy, and/or Surgery in Treating Young Patients With Localized Soft Tissue Sarcoma Unknown status NCT00334854 Phase 3
2 Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma Unknown status NCT00346164 Phase 3
3 Surgery Followed by Chemotherapy in Treating Young Patients With Soft Tissue Sarcoma Completed NCT00002898 Phase 3
4 Surgery With or Without Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Retroperitoneum or Pelvis Completed NCT00091351 Phase 3
5 Doxorubicin With or Without Ifosfamide and Pegfilgrastim in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00061984 Phase 3
6 Ifosfamide or Doxorubicin in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00003212 Phase 3
7 Combination Chemotherapy With or Without Hyperthermia Therapy in Treating Patients With Soft Tissue Sarcoma Completed NCT00003052 Phase 3
8 Surgery With or Without Combination Chemotherapy in Treating Patients With Lung Metastases From Soft Tissue Sarcoma Completed NCT00002764 Phase 3
9 Surgery With or Without Chemotherapy in Treating Patients With Soft Tissue Sarcoma Completed NCT00002641 Phase 3
10 Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-Rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery Recruiting NCT02180867 Phase 2, Phase 3
11 Surgery With or Without Radiation Therapy in Untreated Nonmetastatic Retroperitoneal Sarcoma Recruiting NCT01344018 Phase 3
12 Randomised Trial of Volume of Post-operative Radiotherapy Given to Adult Patients With eXtremity Soft Tissue Sarcoma Active, not recruiting NCT00423618 Phase 3
13 Doxorubicin Hydrochloride or Trabectedin in Treating Patients With Previously Untreated Advanced or Metastatic Soft Tissue Sarcoma Terminated NCT01189253 Phase 2, Phase 3
14 External-Beam Radiation Therapy With or Without Indinavir and Ritonavir in Treating Patients With Brain Metastases Unknown status NCT00637637 Phase 2
15 Brostallicin or Doxorubicin as First-Line Therapy in Treating Patients With Relapsed, Refractory, or Metastatic Soft Tissue Sarcoma Unknown status NCT00410462 Phase 2
16 Temozolomide in Treating Patients With Advanced Soft Tissue Sarcoma Unknown status NCT00003718 Phase 2
17 Imatinib Mesylate in Treating Patients With Advanced Soft Tissue Sarcoma or Bone Sarcoma Completed NCT00031915 Phase 2
18 Phase II Study of Sunitinib Malate for Metastatic and/or Surgically Unresectable Soft Tissue Sarcoma Completed NCT00400569 Phase 2
19 Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas Completed NCT00474994 Phase 2
20 Gemcitabine and Docetaxel With Bevacizumab in Selected Sarcoma Subtypes Completed NCT00887809 Phase 2
21 Bevacizumab and Radiation Therapy for Sarcomas Completed NCT00356031 Phase 2
22 Safety and Efficacy Study of REOLYSIN® in the Treatment of Bone and Soft Tissue Sarcomas Metastatic to the Lung Completed NCT00503295 Phase 2
23 Sorafenib in Treating Patients With Metastatic, Locally Advanced, or Recurrent Sarcoma Completed NCT00245102 Phase 2
24 AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00659360 Phase 2
25 Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma Completed NCT00112463 Phase 2
26 Imatinib Mesylate in Treating Patients With Locally Advanced or Metastatic Dermatofibrosarcoma Protuberans or Giant Cell Fibroblastoma Completed NCT00085475 Phase 2
27 Soblidotin in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00064220 Phase 2
28 Safety and Efficacy Study of Torisel and Liposomal Doxorubicin for Patients With Recurrent Sarcoma Completed NCT00949325 Phase 1, Phase 2
29 BI 2536 in Treating Patients With Recurrent or Metastatic Solid Tumors Completed NCT00526149 Phase 2
30 Perifosine in Treating Patients With Metastatic or Locally Advanced Soft Tissue Sarcoma Completed NCT00053794 Phase 2
31 Brostallicin in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00041249 Phase 2
32 Exatecan Mesylate in Treating Patients With Advanced Soft Tissue Sarcoma Completed NCT00041236 Phase 2
33 STI571 in Treating Patients With Recurrent or Refractory Soft Tissue Sarcoma Completed NCT00006357 Phase 1, Phase 2
34 Ecteinascidin 743 in Treating Patients With Advanced Soft Tissue Sarcoma Completed NCT00003939 Phase 2
35 Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma Completed NCT01154452 Phase 1, Phase 2
36 To Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors Recruiting NCT01962103 Phase 1, Phase 2
37 Autologous Dendritic Cell Vaccine Loaded With Allogeneic Tumor Lysate Expression of Cancer Testis Antigens in Patients With Soft Tissue Sarcoma Recruiting NCT01883518 Phase 1, Phase 2
38 Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma Recruiting NCT02601209 Phase 1, Phase 2
39 Doxorubicin With Upfront Dexrazoxane Plus Olaratumab for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma Recruiting NCT02584309 Phase 2
40 Gemcitabine Hydrochloride With or Without Pazopanib Hydrochloride in Treating Patients With Refractory Soft Tissue Sarcoma Recruiting NCT01532687 Phase 2
41 A Study of Bevacizumab in Combination With Chemotherapy for Treatment of Osteosarcoma Active, not recruiting NCT00667342 Phase 2
42 Alisertib in Treating Patients With Advanced or Metastatic Sarcoma Active, not recruiting NCT01653028 Phase 2
43 Pembrolizumab and Gemcitabine Chemotherapy in Leiomyosarcoma and Undifferentiated Pleomorphic Sarcoma Not yet recruiting NCT03123276 Phase 1, Phase 2
44 Talimogene Laherparepvec and Radiation Therapy in Treating Patients With Newly Diagnosed Soft Tissue Sarcoma That Can Be Removed by Surgery Not yet recruiting NCT02923778 Phase 2
45 Gemcitabine and Docetaxel in Combination With Pazopanib (Gem/Doce/Pzb) for the Neoadjuvant Treatment of Soft Tissue Sarcoma (STS) Terminated NCT01418001 Phase 1, Phase 2
46 Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Stage IB, Stage II, or Stage III Soft Tissue Sarcoma Terminated NCT00740597 Phase 2
47 Celecoxib and Radiation Therapy in Treating Patients With Stage II or Stage III Soft Tissue Sarcoma of the Arm, Hand, Leg, or Foot That Has Been Removed by Surgery Completed NCT00450736 Phase 1
48 Study of PXD101 Alone and in Combination With 5-Fluorouracil (5-FU) in Patients With Advanced Solid Tumors Completed NCT00413322 Phase 1
49 Liposomal Doxorubicin Plus Ifosfamide in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00030784 Phase 1
50 Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma Completed NCT00720174 Phase 1

Search NIH Clinical Center for Histiocytoma

Cochrane evidence based reviews: histiocytoma

Genetic Tests for Histiocytoma

Genetic tests related to Histiocytoma:

id Genetic test Affiliating Genes
1 Histiocytoma 29

Anatomical Context for Histiocytoma

MalaCards organs/tissues related to Histiocytoma:

39
Bone, Breast, Lung, Skin, Heart, Liver, Colon

Publications for Histiocytoma

Articles related to Histiocytoma:

(show top 50) (show all 890)
id Title Authors Year
1
Primary malignant fibrous histiocytoma of long bones: long-term follow-up. ( 27499321 )
2016
2
Fibrous Histiocytoma of the Conjunctiva. ( 27636240 )
2016
3
Conjunctival fibrous histiocytoma in an 8-year-old boy. ( 27282913 )
2016
4
Benign Fibrous Histiocytoma: A Rare Case Report and Literature Review. ( 26929563 )
2016
5
Malignant Fibrous Histiocytoma of the Testicular Appendages Mimicking an Obstructed Hernia in an Elderly Man: Case Report and Review of the Literature. ( 26953736 )
2016
6
'Pure' spindle cell variant of angiomatoid fibrous histiocytoma, lacking classic histologic features. ( 27637157 )
2016
7
Angiomatoid fibrous histiocytoma: novel MR imaging findings. ( 26919861 )
2016
8
Malignant fibrous histiocytoma of the skin. A case treated with radiotherapy. ( 26837483 )
2016
9
Deep Penetrating Fibrous Histiocytoma: A Case Report and Implications for Surgical Management. ( 26999346 )
2016
10
Intracranial Angiomatoid Fibrous Histiocytoma: Case Report and Literature Review. ( 27667574 )
2016
11
14-Year-Old Boy With Mild Antecedent Neck Pain in Setting of Acute Trauma: A Rare Case of Benign Fibrous Histiocytoma of the Spine. ( 26991583 )
2016
12
Benign Fibrous Histiocytoma of the Frontal Bone. ( 27054431 )
2016
13
An unresectable retroperitoneal malignant fibrous histiocytoma: A case report. ( 27073487 )
2016
14
Primary malignant fibrous histiocytoma of the colon: A case report and review of the literature. ( 27284436 )
2016
15
Retrospective characterisation of solitary cutaneous histiocytoma with lymph node metastasis in eight dogs. ( 27486860 )
2016
16
ALK Rearrangement and Overexpression in an Unusual Cutaneous Epithelioid Tumor With a Peculiar Whorled "Perineurioma-like" Growth Pattern: Epithelioid Fibrous Histiocytoma. ( 27438515 )
2016
17
Angiomatoid fibrous histiocytoma: Clinicopathological spectrum of five cases, including EWSR1-CREB1 positive result in a single case. ( 27166030 )
2016
18
Primary malignant fibrous histiocytoma of the liver. ( 27826563 )
2016
19
Subcutaneous Benign Fibrous Histiocytoma: Rare Presentation on Cheek-Case Report and Review of Literature. ( 27408454 )
2016
20
Computed tomography and magnetic resonance imaging findings of malignant fibrous histiocytoma of the head and neck. ( 27123302 )
2016
21
Malignant fibrous histiocytoma of the skin: a case treated with radiotherapy. ( 27176091 )
2016
22
Angiomatoid fibrous histiocytoma: A case of local recurrence and metastases to loco-regional lymph nodes that responded to chemotherapy. ( 28012233 )
2016
23
Benign Fibrous Histiocytoma of Mandible: A Case Report and Updated Review. ( 27504429 )
2016
24
Successful treatment of advanced malignant fibrous histiocytoma of the right forearm with apatinib: a case report. ( 26917971 )
2016
25
Primary Angiomatoid Fibrous Histiocytoma of the Lung with Mediastinal Lymph Node Metastasis. ( 27544801 )
2016
26
A case of recurrent malignant fibrous histiocytoma of the mesentery. ( 27351621 )
2016
27
Double primary malignant fibrous histiocytoma and squamous cell carcinoma of the larynx treated with laser laryngeal conservation surgery. ( 27170836 )
2016
28
Intraspinal extradural benign fibrous histiocytoma of the lumbar spine in a pediatric patient. Case report and literature review. ( 26984808 )
2016
29
Benign fibrous histiocytoma of the fronto-temporo-parietal region: a case report and review of the literature. ( 26823894 )
2015
30
A rare case of malignant fibrous histiocytoma (pleomorphic undifferentiated sarcoma NOS) of the vocal fold. ( 26214667 )
2015
31
Unusual localization of a primary pleomorphic malignant fibrous histiocytoma on the mitral valve: a case report and review of the literature. ( 26518517 )
2015
32
ALK rearrangement and overexpression in epithelioid fibrous histiocytoma. ( 25857825 )
2015
33
Electron microscopic observation of cholesterotic fibrous histiocytoma of the finger. ( 26011092 )
2015
34
Gene fusion detection in formalin-fixed paraffin-embedded benign fibrous histiocytomas using fluorescence in situ hybridization and RNA sequencing. ( 26121314 )
2015
35
Benign fibrous histiocytoma arising at the temporal bone of an infant-case report and review of the literature. ( 26174620 )
2015
36
Paraneoplastic Syndrome of Angiomatoid Fibrous Histiocytoma May Be Caused by EWSR1-CREB1 Fusion-induced Excessive Interleukin-6 Production. ( 26165403 )
2015
37
Benign fibrous histiocytoma of the ethmoids in an infant. ( 26265837 )
2015
38
Metastatic Malignant Fibrous Histiocytoma in the Stomach: Imaging With 18F-FDG PET/CT. ( 26053714 )
2015
39
Giant cell variant of malignant fibrous histiocytoma of male breast: A rare case report. ( 26458656 )
2015
40
Epithelioid sarcoma resembling benign fibrous histiocytoma. ( 25750961 )
2015
41
Clinicopathological features of angiomatoid fibrous histiocytoma: a series of 21 cases with variant morphology. ( 25755773 )
2015
42
A rare case of carcinosarcoma of breast: Coexistence of mucinous carcinoma and malignant fibrous histiocytoma. ( 26881584 )
2015
43
Primary intracranial angiomatoid fibrous histiocytoma presenting with anaemia and migraine-like headaches and aura as early clinical features. ( 25900984 )
2015
44
Benign fibrous histiocytoma of the thoracic spine as the cause of pyrexia of unknown origin identified by positron emission tomography/computed tomography. ( 25771758 )
2015
45
En bloc spondylectomy for primary malignant fibrous histiocytoma of the thoracic spine with aortic involvement: case report. ( 25658464 )
2015
46
Hemosiderotic histiocytoma associated with chronic traumatic stress in a patient with spinal cord injury. ( 26388209 )
2015
47
Malignant fibrous histiocytoma of visceral organs: clinicopathologic features and diagnostic value of ezrin and HMG-CoA reductase. ( 26045796 )
2015
48
A Case of Cellular Fibrous Histiocytoma on the Right Elbow with Repeated Relapse within a Short Period. ( 25759652 )
2015
49
Deep benign fibrous histiocytoma in the oral cavity: a case report. ( 26568930 )
2015
50
Characterization of metastatic angiomatoid fibrous histiocytoma. ( 25757019 )
2015

Variations for Histiocytoma

Expression for Histiocytoma

Search GEO for disease gene expression data for Histiocytoma.

Pathways for Histiocytoma

Pathways related to Histiocytoma according to GeneCards Suite gene sharing:

(show all 27)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.81 CDK4 CREB1 KIT MDM2 MITF TP53
2
Show member pathways
12.45 CDK4 CREB1 MDM2 TP53
3 12.45 CDK4 KIT MDM2 MITF TP53
4 12.34 CDK4 CREB1 KIT MDM2 TP53
5 12.3 ATF1 CDK4 CREB1 TP53
6
Show member pathways
12.22 CDK4 CREB1 MDM2 TP53
7
Show member pathways
12.19 CREB1 KIT MITF TP53
8 12.13 CDK4 CREB1 MDM2 TP53
9 11.91 ATF1 EWSR1 FUS MDM2 TP53
10 11.87 CD163 KIT PTPRC
11 11.84 CDK4 MDM2 TP53
12 11.79 ATF1 CREB1 MYOD1
13 11.77 KIT MYOD1 PTPRC
14 11.74 ATF1 CDK4 CREB1 MDM2 TP53
15 11.73 CDK4 MDM2 TP53
16
Show member pathways
11.71 CREB1 MDM2 TP53
17 11.67 CREB1 MDM2 TP53
18 11.64 CDK4 CREB1 MYOD1
19 11.62 CD163 KIT PTPRC
20 11.59 CDK4 MDM2 TP53
21 11.43 MDM2 MITF MYOD1
22 11.4 CREB1 MDM2 TP53
23 11.25 CDK4 MDM2 TP53
24 11.16 CREB1 KIT MITF
25 11 CDK4 MDM2 TP53
26 10.92 ATF1 CDK4 MDM2 TP53
27 10.47 ATF1 CREB1 MITF TP53

GO Terms for Histiocytoma

Cellular components related to Histiocytoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 transcription factor complex GO:0005667 8.92 ATF1 CDK4 CREB1 MYOD1

Biological processes related to Histiocytoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 transcription from RNA polymerase II promoter GO:0006366 9.35 ATF1 CREB1 MITF MYOD1 TP53
2 cellular response to actinomycin D GO:0072717 8.62 MDM2 TP53

Molecular functions related to Histiocytoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein binding GO:0005515 9.83 ATF1 CD163 CDK4 CREB1 EWSR1 FUS
2 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding GO:0001228 9.33 ATF1 MYOD1 TP53
3 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding GO:0003705 8.8 ATF1 CREB1 MYOD1

Sources for Histiocytoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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