Aliases & Classifications for Histiocytoma

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Histiocytoma, Aliases & Descriptions:

Name: Histiocytoma 9 11 60
 
Cutaneous Fibrous Histiocytoma 60


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Disease Ontology9 DOID:4231
NCIt38 C35765
MeSH33 D051642

Summaries for Histiocytoma

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Wikipedia:63 A histiocytoma is a tumour consisting of histiocytes. Histiocytes are cells that are a part of the... more...

MalaCards based summary: Histiocytoma, also known as cutaneous fibrous histiocytoma, is related to fibrous histiocytoma and histiocytosis. An important gene associated with Histiocytoma is ATF1 (activating transcription factor 1), and among its related pathways are Aurora B signaling and Cytoskeletal Signaling. The compounds eosin and silver have been mentioned in the context of this disorder. Affiliated tissues include bone, breast and lung, and related mouse phenotypes are muscle and normal.

Related Diseases for Histiocytoma

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Diseases related to Histiocytoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 234)
idRelated DiseaseScoreTop Affiliating Genes
1fibrous histiocytoma32.3CREB1, FUS
2histiocytosis31.1S100B
3cutaneous fibrous histiocytoma30.9DES, F13A1, ACTC1, S100B
4dedifferentiated liposarcoma30.6DES, MDM2
5myxoid liposarcoma30.6ATF1
6fasciitis30.5ACTC1
7langerhans-cell histiocytosis30.4F13A1, S100B
8rosai-dorfman disease30.4S100B
9liposarcoma30.3MDM2, VIM, FUS, DES
10rhabdoid tumor30.3DES, VIM, ACTC1
11chordoma30.3S100B, VIM, DES
12angiosarcoma30.3SERPINA3, VIM, ACTC1
13perineurioma30.3VIM, S100B
14dermatofibrosarcoma protuberans30.2DES, F13A1, VIM, ACTC1, S100B
15fibrosarcoma30.1MDM2, ACTC1, VIM, DES
16giant cell tumor30.1VIM, IL6R
17fibromatosis30.1ACTC1, VIM, DES
18spindle cell sarcoma30.1DES, VIM, ACTC1, S100B
19tuberous sclerosis30.0S100B, VIM, F13A1
20neurofibromatosis29.9S100B, CREB1
21leiomyosarcoma29.8DES, VIM, ACTC1, S100B, MDM2
22leiomyoma29.8S100B, ACTC1, VIM, DES
23sarcoma29.7DES, ATF1, FUS, F13A1, VIM, ACTC1
24hemangiopericytoma29.4MDM2, S100B, ACTC1, VIM, F13A1, DES
25hepatocellular carcinoma29.4ATF1, F13A1, IL6R, CREB1, MDM2
26rhabdomyosarcoma29.3DES, VIM, ACTC1, S100B, MDM2
27adenocarcinoma29.2F13A1, SERPINA3, VIM, ACTC1, CREB1, MDM2
28malignant fibroxanthoma29.1MDM2, S100B, IL6R, ACTC1, VIM, SERPINA3
29breast cancer29.1MDM2, IL6R, ACTC1, VIM, SERPINA3
30leukemia29.1ATF1, FUS, SERPINA3, IL6R, CREB1, MDM2
31melanoma28.5DES, ATF1, F13A1, SERPINA3, VIM, ACTC1
32malignant fibrous histiocytoma of bone10.8
33diaphyseal medullary stenosis with malignant fibrous histiocytoma10.5
34infantile myofibromatosis10.5DES
35pleomorphic malignant fibrous histiocytoma10.5
36syringoma10.5S100B
37adenomatoid tumor10.4VIM
38fibrous meningioma10.4S100B
39aneurysm10.4
40essential tremor10.4VIM
41hepatitis10.4
42mesenchymal chondrosarcoma10.4DES, VIM
43ganglioglioma10.4S100B
44alveolar soft-part sarcoma10.3DES, VIM
45peripheral primitive neuroectodermal tumor10.3ATF1, FUS
46sertoli cell tumor10.3DES, VIM
47desmoid disease, hereditary10.3ACTC1, DES
48undifferentiated pleomorphic sarcoma10.3
49giant cell glioblastoma10.3MDM2
50adenosarcoma10.3DES, ACTC1

Graphical network of the top 20 diseases related to Histiocytoma:



Diseases related to histiocytoma

Symptoms for Histiocytoma

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Drugs & Therapeutics for Histiocytoma

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Drug clinical trials:

Search ClinicalTrials for Histiocytoma

Search NIH Clinical Center for Histiocytoma

Genetic Tests for Histiocytoma

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Anatomical Context for Histiocytoma

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MalaCards organs/tissues related to Histiocytoma:

31
Bone, Breast, Lung, Heart, Skin, Liver, Spleen, Colon, Kidney, Pancreas, Thyroid, Ovary, T cells, Cervix, Tongue, Trachea, Lymph node, Thymus, Brain, Smooth muscle, Adrenal gland, Prostate, Testes, Bone marrow, Skeletal muscle, Uterus, Testis, Monocytes, Endothelial

Animal Models for Histiocytoma or affiliated genes

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MGI Mouse Phenotypes related to Histiocytoma:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053698.1MDM2, CREB1, ACTC1, VIM, DES
2MP:00028737.5ATF1, ACTC1, IL6R, CREB1, S100B, MDM2
3MP:00053857.5DES, F13A1, VIM, ACTC1, CREB1, MDM2
4MP:00053867.1DES, FUS, VIM, IL6R, CREB1, S100B
5MP:00053847.0ATF1, FUS, VIM, ACTC1, IL6R, CREB1
6MP:00107686.6MDM2, DES, ATF1, FUS, F13A1, VIM

Publications for Histiocytoma

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Articles related to Histiocytoma:

(show top 50)    (show all 814)
idTitleAuthorsYear
1
Primary pulmonary malignant fibrous histiocytoma. (25838959)
2015
2
Malignant fibrous histiocytoma: an uncommon sarcoma with pathological fracture of mandible. (25838711)
2015
3
Epidermal inclusion cyst embedded in a recurrent benign fibrous histiocytoma. (25284857)
2014
4
Primary hepatic malignant fibrous histiocytoma mimicking hepatocellular carcinoma: A report of two cases. (25295102)
2014
5
Cytomorphometry of canine cutaneous histiocytoma. (25286647)
2014
6
Refractory Malignant Fibrous Histiocytoma: CT-guided Treatment with a Multidisciplinary, Minimally Invasive Approach. (24325132)
2013
7
An adolescent presenting with malignant fibrous histiocytoma of the testis: a case report. (23347569)
2013
8
Primary malignant fibrous histiocytoma of the renal pelvis: a 78-month follow-up case report. (24368887)
2013
9
A therapeutic strategy for metastatic malignant fibrous histiocytoma through mesenchymal stromal cell-mediated TRAIL production. (23108118)
2013
10
Cholesterotic Fibrous Histiocytoma. (23518637)
2013
11
Malignant fibrous histiocytoma of the breast in young male patient: a case report and a review of the literature. (23573437)
2013
12
Malignant fibrous histiocytoma at the site of an alumina-on-alumina-bearing total hip arthroplasty mimicking infected trochanteric bursitis. (21435828)
2012
13
Clinical and pathologic characteristics and surgical management of benign fibrous histiocytoma of the mandible: a case report. (22580097)
2012
14
Benign fibrous histiocytoma of vulva: rare case. (24293888)
2012
15
A p53 gene mutation in malignant fibrous histiocytoma associated with bone infarction. (22041521)
2011
16
Malignant fibrous histiocytoma two years after autologous stem cell transplant for Hodgkin lymphoma: evidence for genomic instability. (21488163)
2011
17
Primary hepatic malignant fibrous histiocytoma: diagnostic pitfalls and therapeutic challenge. (21830410)
2011
18
Benign fibrous histiocytoma of bone in a paediatric population: a report of 6 cases. (21409501)
2011
19
Phase II study of sunitinib malate, a multitargeted tyrosine kinase inhibitor in patients with relapsed or refractory soft tissue sarcomas. Focus on three prevalent histologies: leiomyosarcoma, liposarcoma and malignant fibrous histiocytoma. (21154746)
2011
20
Malignant fibrous histiocytoma of the small bowel with colon metastasis. (21590606)
2011
21
Pleomorphic malignant fibrous histiocytoma/undifferentiated high-grade pleomorphic sarcoma of the scrotum in a patient presenting as fournier gangrene: a case report. (20505510)
2010
22
An angiomatoid fibrous histiocytoma over the left pre auricular region in a 13-year-old boy. (20492821)
2010
23
Prognostic significance of ezrin expression in pleomorphic malignant fibrous histiocytoma. (17465259)
2007
24
Squamous epithelial-lined cyst occurring in an aneurysmal fibrous histiocytoma. (17519635)
2007
25
Benign fibrous histiocytoma associated with a frontoethmoidal mucopyocele and orbital abscess. (17519668)
2007
26
Malignant fibrous histiocytoma of the parotid gland. (18188922)
2007
27
Fibrous Histiocytoma-like Spindle-Cell Proliferation in the Nipple After Body-Piercing. (16501844)
2006
28
Angiomatoid variant of fibrous histiocytoma: a case report and review of literature. (16879335)
2006
29
Diaphyseal medullary stenosis with pleomorphic malignant fibrous histiocytoma of the bone: 99mTc hydroxymethylenediphosphonate and 201Tl chloride scintigraphy findings. (16715956)
2006
30
Generalized eruptive histiocytoma: a pediatric case. (17229617)
2006
31
Aneurysmal fibrous histiocytoma of the skin: a rare variant of dermatofibroma. (16327640)
2005
32
Primary malignant fibrous histiocytoma of the pancreas: a case with K-ras mutation and a review of the literature. (16416164)
2005
33
Primary malignant fibrous histiocytoma of the jejunum metastatic to the spine: report of a case. (15879629)
2005
34
Malignant fibrous histiocytoma arising from the renal capsule. (16327309)
2005
35
Expression of matrix metalloproteinase-9 correlates with poor prognosis in human malignant fibrous histiocytoma. (20368833)
2004
36
Expression profiling using tissue microarray in 211 malignant fibrous histiocytomas confirms the prognostic value of Ki-67. (15309631)
2004
37
Evaluation of immunohistochemical parameters as prognostic markers in malignant fibrous histiocytoma. (12883752)
2003
38
Clinicopathologic features, diagnosis, and treatment of malignant fibrous histiocytoma of bone. (10642003)
2000
39
Cytogenetic, ras, and p53: studies in cases of canine neoplasms (hemangiopericytoma, mastocytoma, histiocytoma, chloroma). (9987918)
1999
40
Dedifferentiated liposarcoma with an inflammatory malignant fibrous histiocytoma-like component presenting a leukemoid reaction. (9311018)
1997
41
Cutaneous fibrous histiocytoma with osteoclast-like giant cells. (8863988)
1996
42
P-53 positivity and high proliferative index: factors of bad prognosis in malignant fibrous histiocytomas. (8900926)
1995
43
Palisading cutaneous fibrous histiocytoma. An immunohistochemical study demonstrating differentiation from dermal dendrocytes. (8311187)
1993
44
Phenotypic characterization of the human fibrous histiocytoma giant cell tumor (GCT) cell line and its cytokine repertoire. (7689482)
1993
45
p53 immunohistochemistry in malignant fibrous histiocytomas and other mesenchymal tumours. (1333524)
1992
46
Malignant fibrous histiocytomas in dogs and cats: an immunohistochemical study. (1332152)
1992
47
Angioleiomyoma within a histiocytoma. (2258477)
1990
48
Chemotherapy-induced complete remission of a malignant fibrous histiocytoma of bone. An 11-year follow-up. (3008679)
1986
49
Postradiation malignant fibrous histiocytoma of bone. A clinicopathologic study of 20 patients. (3006524)
1986
50
Malignant fibrous histiocytoma of bone. (6262217)
1980

Variations for Histiocytoma

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Expression for genes affiliated with Histiocytoma

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Search GEO for disease gene expression data for Histiocytoma.

Pathways for genes affiliated with Histiocytoma

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Pathways related to Histiocytoma according to GeneCards Suite gene sharing:

(show all 14)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Signaling by Aurora kinases36
Aurora C signaling36
9.9DES, VIM
29.5DES, VIM, ACTC1
3
Show member pathways
9.5ACTC1, VIM, DES
49.4ATF1, CREB1
59.4CREB1, ATF1
69.4CREB1, ATF1
79.1CREB1, IL6R
89.1ATF1, FUS, MDM2
9
Show member pathways
ATM Signaling Pathway36
9.0MDM2, CREB1
10
Show member pathways
Calcium Regulation in the Cardiac Cell36
9.0CREB1, ACTC1, ATF1
11
Show member pathways
9.0ATF1, CREB1, S100B
128.8MDM2, CREB1, ATF1
13
Show member pathways
8.6MDM2, S100B, CREB1
14
Show member pathways
7.6MDM2, DES, ATF1, VIM, IL6R, CREB1

Compounds for genes affiliated with Histiocytoma

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Compounds related to Histiocytoma according to GeneCards Suite gene sharing:

(show top 50)    (show all 87)
idCompoundScoreTop Affiliating Genes
1eosin439.7S100B, VIM
2silver439.7DES, F13A1, SERPINA3
3procollagen439.6DES, F13A1, VIM, ACTC1
4orcein439.5DES, VIM, ACTC1, S100B
5mucicarmine439.5DES, VIM, ACTC1, S100B
6formaldehyde43 2410.4DES, VIM, ACTC1, S100B
7methionine439.4S100B, VIM, SERPINA3, DES
8fibrinogen439.2DES, F13A1, SERPINA3, IL6R
9s 100439.2S100B, ACTC1, VIM, F13A1, DES
10reticulin439.2DES, F13A1, VIM, ACTC1, S100B
11b 723439.2S100B, ACTC1, VIM, F13A1, DES
12hematoxylin439.2DES, F13A1, VIM, ACTC1, S100B
13heparin43 28 24 1212.1DES, F13A1, SERPINA3, VIM, S100B
14imatinib43 49 1211.1MDM2, S100B, ACTC1, DES
15dbc-amp439.1S100B, CREB1, VIM
16valine439.1MDM2, S100B, VIM, SERPINA3
17methotrexate49 43 1210.9MDM2, IL6R, VIM, SERPINA3
18norepinephrine43 24 1210.9S100B, CREB1, ATF1, DES
19proline438.8MDM2, S100B, VIM, DES
20azathioprine43 2 49 1211.8CREB1, VIM, DES
21acetylcholine43 49 28 24 1212.7DES, SERPINA3, VIM, CREB1, S100B
22adenylate438.7DES, ATF1, VIM, CREB1, S100B
2312-o-tetradecanoylphorbol 13-acetate438.6CREB1, IL6R, VIM, ATF1, DES
24creatinine438.6DES, SERPINA3, VIM, ACTC1, IL6R, S100B
25glucose438.6DES, ATF1, SERPINA3, ACTC1, IL6R, S100B
26etoposide43 49 59 1211.6VIM, CREB1, S100B, MDM2
27forskolin43 49 1210.6ATF1, VIM, CREB1, S100B
28actinomycin d438.5DES, VIM, CREB1, MDM2
29glutamine438.5F13A1, VIM, IL6R, CREB1, S100B
30arginine438.3DES, SERPINA3, VIM, IL6R, S100B, MDM2
31paraffin438.3DES, F13A1, SERPINA3, VIM, ACTC1, S100B
32leucine438.2ATF1, FUS, SERPINA3, VIM, CREB1, S100B
33iron43 249.2DES, F13A1, SERPINA3, VIM, ACTC1, S100B
34threonine438.2DES, SERPINA3, CREB1, S100B, MDM2
35wortmannin438.1VIM, IL6R, CREB1, S100B, MDM2
36cyclic amp43 249.1DES, ATF1, VIM, CREB1, S100B, MDM2
37cysteine438.0DES, SERPINA3, VIM, CREB1, S100B, MDM2
38estradiol43 24 1210.0DES, SERPINA3, VIM, IL6R, CREB1, MDM2
39retinoic acid43 248.8DES, SERPINA3, VIM, ACTC1, IL6R, CREB1
40serine437.7DES, ATF1, SERPINA3, VIM, CREB1, S100B
41oligonucleotide437.7ATF1, F13A1, SERPINA3, VIM, IL6R, CREB1
42zinc43 248.7FUS, SERPINA3, IL6R, CREB1, S100B, MDM2
43glycogen43 248.6DES, VIM, ACTC1, IL6R, CREB1, S100B
44testosterone43 59 24 1210.5DES, VIM, ACTC1, IL6R, CREB1, S100B
45progesterone43 28 59 24 1211.5DES, ATF1, F13A1, SERPINA3, VIM, ACTC1
46dexamethasone43 49 28 1210.5SERPINA3, VIM, ACTC1, IL6R, CREB1, S100B
47estrogen437.4DES, F13A1, SERPINA3, VIM, ACTC1, CREB1
48steroid437.3DES, ATF1, SERPINA3, ACTC1, IL6R, CREB1
49vegf437.3DES, F13A1, VIM, ACTC1, IL6R, CREB1
50calcium43 49 24 129.9DES, ATF1, F13A1, SERPINA3, ACTC1, IL6R

GO Terms for genes affiliated with Histiocytoma

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Cellular components related to Histiocytoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1blood microparticleGO:00725629.5ACTC1, SERPINA3, F13A1

Biological processes related to Histiocytoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1muscle filament slidingGO:00300499.6ACTC1, VIM, DES
2acute-phase responseGO:00069539.5SERPINA3, IL6R
3response to drugGO:00424938.7MDM2, CREB1, ACTC1
4neurotrophin TRK receptor signaling pathwayGO:00480118.5MDM2, CREB1, ATF1
5innate immune responseGO:00450878.4MDM2, S100B, CREB1, ATF1

Molecular functions related to Histiocytoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1scaffold protein bindingGO:00971109.5MDM2, VIM
2identical protein bindingGO:00428028.1DES, FUS, VIM, S100B, MDM2
3protein bindingGO:00055155.8MDM2, DES, ATF1, FUS, MFHAS1, SERPINA3

Products for genes affiliated with Histiocytoma

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Sources for Histiocytoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet