Aliases & Classifications for Histiocytoma

MalaCards integrated aliases for Histiocytoma:

Name: Histiocytoma 12 29 42 14 69
Cutaneous Fibrous Histiocytoma 69

Classifications:



External Ids:

Disease Ontology 12 DOID:4231
MeSH 42 D051642
NCIt 47 C35765
UMLS 69 C1509147

Summaries for Histiocytoma

MalaCards based summary : Histiocytoma, also known as cutaneous fibrous histiocytoma, is related to liposarcoma and fibrosarcoma of bone. An important gene associated with Histiocytoma is ATF1 (Activating Transcription Factor 1), and among its related pathways/superpathways are PI3K-Akt signaling pathway and Mitotic G1-G1/S phases. The drugs Doxorubicin and Ifosfamide have been mentioned in the context of this disorder. Affiliated tissues include bone, lung and skin, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and cardiovascular system

Wikipedia : 72 A histiocytoma is a tumour consisting of histiocytes. Histiocytes are cells that are a part of the... more...

Related Diseases for Histiocytoma

Diseases related to Histiocytoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 266)
id Related Disease Score Top Affiliating Genes
1 liposarcoma 31.0 EWSR1 MDM2
2 fibrosarcoma of bone 29.3 EWSR1 KIT MYOD1
3 spindle cell sarcoma 22.1 ATF1 CD163 CDK4 CREB1 EWSR1 FUS
4 diaphyseal medullary stenosis with malignant fibrous histiocytoma 12.3
5 fibrous histiocytoma 12.3
6 histiocytoma, angiomatoid fibrous, somatic 12.1
7 cutaneous fibrous histiocytoma 12.0
8 malignant fibrous histiocytoma of bone 12.0
9 malignant skin fibrous histiocytoma 11.8
10 undifferentiated pleomorphic sarcoma 11.7
11 benign deep fibrous histiocytoma 11.7
12 generalized eruptive histiocytosis 11.6
13 myxofibrosarcoma 11.5
14 sclerosing hemangioma 11.2
15 malignant fibroxanthoma 11.2
16 urachal cancer 10.8
17 tenosynovial giant cell tumor 10.7
18 reticulohistiocytic granuloma 10.7
19 parkinsonism with dementia of guadeloupe 10.7 ATF1 CREB1 EWSR1
20 chondroid chordoma 10.6 EWSR1 MB
21 thymus large cell carcinoma 10.6 EWSR1 FUS
22 epidural neoplasm 10.6 CDK4 MDM2
23 skin lipoma 10.6 CDK4 MDM2
24 metachronous osteosarcoma of the bone 10.5 CDK4 MDM2
25 acute cholinergic dysautonomia 10.5 MDM2 TP53
26 leg dermatosis 10.5 CD163 SERPINA3
27 properdin deficiency 10.5 MB MTAP
28 lipoic acid biosynthesis defects 10.5 CDK4 MDM2
29 malignant giant cell tumor of the tendon sheath 10.5 PTPRC SERPINA3
30 cowper gland carcinoma 10.4 MB TP53
31 heel spur 10.4 EWSR1 PTPRC
32 transverse colon cancer 10.4 EWSR1 FUS
33 cholelithiasis 10.4 CDK4 FUS MDM2
34 bile duct sarcoma 10.4 MB MYOD1
35 acromegaly 10.4 CD163 SERPINA3
36 rhabditida infections 10.4 MDM2 PTPRC
37 reactive arthritis 10.4 CDK4 MDM2 SERPINA3
38 rectum squamous cell carcinoma 10.4 MDM2 TP53
39 sarcosinemia 10.4 CDK4 FUS MDM2
40 lichen nitidus 10.4 MDM2 TP53
41 spleen cancer 10.4 MB MYOD1
42 trichorhinophalangeal syndrome, type ii 10.4 EWSR1 MDM2 MTAP
43 mucinous ovarian cystadenoma 10.3 MB MYOD1
44 leydig cell tumor 10.3 CD163 CDK4 EWSR1
45 adult central nervous system germinoma 10.3 CD163 PTPRC
46 sparse hair ptosis mental retardation 10.3 EWSR1 MDM2 TP53
47 teeth hard tissue disease 10.3 CD163 PTPRC
48 spondyloepimetaphyseal dysplasia, isidor type 10.3 EWSR1 FUS PTPRC
49 penis paget's disease 10.3 SERPINA3 TP53
50 mucinous intrahepatic cholangiocarcinoma 10.3 CD163 CDK4 MDM2

Graphical network of the top 20 diseases related to Histiocytoma:



Diseases related to Histiocytoma

Symptoms & Phenotypes for Histiocytoma

GenomeRNAi Phenotypes related to Histiocytoma according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-1 9.62 CD163
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-104 9.62 CD163
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-111 9.62 CD163
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-112 9.62 FUS
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-116 9.62 CDK4
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-134 9.62 CD163
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-184 9.62 CD163
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-203 9.62 EWSR1
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-216 9.62 EWSR1
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-40 9.62 FUS
11 Decreased shRNA abundance (Z-score < -2) GR00366-A-53 9.62 CDK4 EWSR1
12 Decreased shRNA abundance (Z-score < -2) GR00366-A-60 9.62 FUS
13 Decreased shRNA abundance (Z-score < -2) GR00366-A-77 9.62 FUS CD163 CDK4 EWSR1
14 Decreased shRNA abundance (Z-score < -2) GR00366-A-84 9.62 EWSR1
15 Decreased shRNA abundance (Z-score < -2) GR00366-A-89 9.62 EWSR1
16 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.62 CD163

MGI Mouse Phenotypes related to Histiocytoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.91 CD163 CDK4 CREB1 KIT MB MDM2
2 muscle MP:0005369 9.76 CD163 CDK4 CREB1 KIT MB MDM2
3 neoplasm MP:0002006 9.43 CDK4 KIT MDM2 MYOD1 PTPRC TP53
4 respiratory system MP:0005388 9.17 CREB1 KIT MB MTAP MYOD1 PTPRC

Drugs & Therapeutics for Histiocytoma

Drugs for Histiocytoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 105)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Doxorubicin Approved, Investigational Phase 3,Phase 2,Phase 1 23214-92-8 31703
2
Ifosfamide Approved Phase 3,Phase 2,Phase 1 3778-73-2 3690
3
Mechlorethamine Approved Phase 3,Phase 2,Phase 1 51-75-2 4033
4
Vincristine Approved, Investigational Phase 3 2068-78-2, 57-22-7 5978
5
Etoposide Approved Phase 3,Phase 2 33419-42-0 36462
6
Carboplatin Approved Phase 3 41575-94-4 10339178 498142 38904
7
Cyclophosphamide Approved, Investigational Phase 3,Phase 2 50-18-0, 6055-19-2 2907
8
Lenograstim Approved Phase 3,Phase 2 135968-09-1
9
Dactinomycin Approved Phase 3 50-76-0 2019 457193
10
Epirubicin Approved Phase 3 56420-45-2 41867
11
Trabectedin Approved, Investigational Phase 2, Phase 3 114899-77-3 108150
12
Doxil Approved June 1999 Phase 3,Phase 2,Phase 1 31703
13 Isophosphamide mustard Phase 3,Phase 2,Phase 1
14 Alkylating Agents Phase 3,Phase 2,Phase 1
15 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1
16 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1
17 Anti-Infective Agents Phase 3,Phase 2,Phase 1
18 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1
19 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 2
20 Etoposide phosphate Phase 3,Phase 2
21 Immunosuppressive Agents Phase 3,Phase 2,Phase 1
22 Antirheumatic Agents Phase 3,Phase 2,Phase 1
23 Antimitotic Agents Phase 3,Phase 2,Phase 1
24 Antineoplastic Agents, Phytogenic Phase 3,Phase 2,Phase 1
25
Ritonavir Approved, Investigational Phase 2 155213-67-5 392622
26
Indinavir Approved Phase 2 150378-17-9 5362440
27
Dacarbazine Approved, Investigational Phase 2 4342-03-4 5351166
28
Temozolomide Approved, Investigational Phase 2 85622-93-1 5394
29
Gemcitabine Approved Phase 2,Phase 1 95058-81-4 60750
30
Sorafenib Approved, Investigational Phase 2 284461-73-0 216239 406563
31
Miconazole Approved, Investigational, Vet_approved Phase 1, Phase 2 22916-47-8 4189
32
Everolimus Approved Phase 1, Phase 2 159351-69-6 6442177
33
Sunitinib Approved, Investigational Phase 2 341031-54-7, 557795-19-4 5329102
34
Bevacizumab Approved, Investigational Phase 2 216974-75-3
35
Sirolimus Approved, Investigational Phase 1, Phase 2 53123-88-9 5284616 6436030 46835353
36
Romidepsin Approved, Investigational Phase 2 128517-07-7 5352062
37
nivolumab Approved Phase 2,Phase 1 946414-94-4
38
Paclitaxel Approved, Vet_approved Phase 1, Phase 2 33069-62-4 36314
39
Cisplatin Approved Phase 2 15663-27-1 84093 441203 2767
40
Methotrexate Approved Phase 2 1959-05-2, 59-05-2 126941
41
Pembrolizumab Approved Phase 1, Phase 2 1374853-91-4
42
Niacin Approved, Investigational, Nutraceutical Phase 2 59-67-6 938
43
Nicotinamide Approved, Nutraceutical Phase 2 98-92-0 936
44
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2 59-30-3 6037
45
leucovorin Approved, Nutraceutical Phase 2 58-05-9 143 6006
46
Docetaxel Approved May 1996, Investigational Phase 2,Phase 1 114977-28-5 148124 9877265
47
Camptothecin Experimental Phase 2 7689-03-4
48 Exatecan Investigational Phase 2 171335-80-1
49
Saracatinib Investigational Phase 2 379231-04-6
50 Soblidotin Investigational Phase 2 149606-27-9

Interventional clinical trials:

(show top 50) (show all 65)

id Name Status NCT ID Phase Drugs
1 Ifosfamide and Doxorubicin, Radiation Therapy, and/or Surgery in Treating Young Patients With Localized Soft Tissue Sarcoma Unknown status NCT00334854 Phase 3 doxorubicin hydrochloride;ifosfamide
2 Surgery Followed by Chemotherapy in Treating Young Patients With Soft Tissue Sarcoma Completed NCT00002898 Phase 3 carboplatin;cyclophosphamide;epirubicin hydrochloride;etoposide;ifosfamide;vincristine sulfate
3 Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma Completed NCT00346164 Phase 3 doxorubicin hydrochloride;ifosfamide
4 Surgery With or Without Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Retroperitoneum or Pelvis Completed NCT00091351 Phase 3
5 Doxorubicin With or Without Ifosfamide and Pegfilgrastim in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00061984 Phase 3 doxorubicin hydrochloride;ifosfamide
6 Ifosfamide or Doxorubicin in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00003212 Phase 3 doxorubicin hydrochloride;ifosfamide
7 Combination Chemotherapy With or Without Hyperthermia Therapy in Treating Patients With Soft Tissue Sarcoma Completed NCT00003052 Phase 3 doxorubicin hydrochloride;etoposide;ifosfamide
8 Surgery With or Without Combination Chemotherapy in Treating Patients With Lung Metastases From Soft Tissue Sarcoma Completed NCT00002764 Phase 3 doxorubicin hydrochloride;ifosfamide
9 Surgery With or Without Chemotherapy in Treating Patients With Soft Tissue Sarcoma Completed NCT00002641 Phase 3 doxorubicin hydrochloride;ifosfamide;isolated perfusion
10 Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery Recruiting NCT02180867 Phase 2, Phase 3 Doxorubicin Hydrochloride;Ifosfamide;Pazopanib Hydrochloride
11 Surgery With or Without Radiation Therapy in Untreated Nonmetastatic Retroperitoneal Sarcoma Recruiting NCT01344018 Phase 3
12 Randomised Trial of Volume of Post-operative Radiotherapy Given to Adult Patients With eXtremity Soft Tissue Sarcoma Active, not recruiting NCT00423618 Phase 3
13 Doxorubicin Hydrochloride or Trabectedin in Treating Patients With Previously Untreated Advanced or Metastatic Soft Tissue Sarcoma Terminated NCT01189253 Phase 2, Phase 3 doxorubicin hydrochloride;trabectedin
14 External-Beam Radiation Therapy With or Without Indinavir and Ritonavir in Treating Patients With Brain Metastases Unknown status NCT00637637 Phase 2 indinavir sulfate;ritonavir
15 Brostallicin or Doxorubicin as First-Line Therapy in Treating Patients With Relapsed, Refractory, or Metastatic Soft Tissue Sarcoma Unknown status NCT00410462 Phase 2 brostallicin;doxorubicin hydrochloride
16 Temozolomide in Treating Patients With Advanced Soft Tissue Sarcoma Unknown status NCT00003718 Phase 2 temozolomide
17 Imatinib Mesylate in Treating Patients With Advanced Soft Tissue Sarcoma or Bone Sarcoma Completed NCT00031915 Phase 2 imatinib mesylate
18 Phase II Study of Sunitinib Malate for Metastatic and/or Surgically Unresectable Soft Tissue Sarcoma Completed NCT00400569 Phase 2 Sunitinib Malate (SU011248)
19 Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas Completed NCT00474994 Phase 2 sunitinib malate
20 Gemcitabine and Docetaxel With Bevacizumab in Selected Sarcoma Subtypes Completed NCT00887809 Phase 2 gemcitabine;docetaxel;bevacizumab
21 Bevacizumab and Radiation Therapy for Sarcomas Completed NCT00356031 Phase 2 Bevacizumab
22 Safety and Efficacy Study of REOLYSIN® in the Treatment of Bone and Soft Tissue Sarcomas Metastatic to the Lung Completed NCT00503295 Phase 2
23 AZD0530 in Treating Patients With Recurrent Locally Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00659360 Phase 2 saracatinib
24 Sorafenib in Treating Patients With Metastatic, Locally Advanced, or Recurrent Sarcoma Completed NCT00245102 Phase 2 sorafenib tosylate
25 Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma Completed NCT00112463 Phase 2 romidepsin
26 Imatinib Mesylate in Treating Patients With Locally Advanced or Metastatic Dermatofibrosarcoma Protuberans or Giant Cell Fibroblastoma Completed NCT00085475 Phase 2 imatinib mesylate
27 Soblidotin in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00064220 Phase 2 soblidotin
28 Safety and Efficacy Study of Torisel and Liposomal Doxorubicin for Patients With Recurrent Sarcoma Completed NCT00949325 Phase 1, Phase 2 temsirolimus (Torisel) plus liposomal doxorubicin (Doxil)
29 BI 2536 in Treating Patients With Recurrent or Metastatic Solid Tumors Completed NCT00526149 Phase 2 BI 2536
30 Perifosine in Treating Patients With Metastatic or Locally Advanced Soft Tissue Sarcoma Completed NCT00053794 Phase 2 perifosine
31 Brostallicin in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma Completed NCT00041249 Phase 2 brostallicin
32 Exatecan Mesylate in Treating Patients With Advanced Soft Tissue Sarcoma Completed NCT00041236 Phase 2 exatecan mesylate
33 STI571 in Treating Patients With Recurrent or Refractory Soft Tissue Sarcoma Completed NCT00006357 Phase 1, Phase 2 imatinib mesylate
34 Ecteinascidin 743 in Treating Patients With Advanced Soft Tissue Sarcoma Completed NCT00003939 Phase 2 trabectedin
35 Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma Completed NCT01154452 Phase 1, Phase 2 Gamma-Secretase Inhibitor RO4929097;Vismodegib
36 Study of Neoadjuvant Checkpoint Blockade in Patients With Surgically Resectable Undifferentiated Pleomorphic Sarcoma and Dedifferentiated Liposarcoma Recruiting NCT03307616 Phase 2 Nivolumab;Ipilimumab
37 Autologous Dendritic Cell Vaccine Loaded With Allogeneic Tumor Lysate Expression of Cancer Testis Antigens in Patients With Soft Tissue Sarcoma Recruiting NCT01883518 Phase 1, Phase 2
38 Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Sarcoma That Cannot Be Removed by Surgery Recruiting NCT02500797 Phase 2
39 Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma Recruiting NCT03190174 Phase 1, Phase 2 Nab-Rapamycin
40 Doxorubicin With Upfront Dexrazoxane Plus Olaratumab for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma Recruiting NCT02584309 Phase 2 Dexrazoxane;Doxorubicin;Olaratumab
41 Gemcitabine Hydrochloride With or Without Pazopanib Hydrochloride in Treating Patients With Refractory Soft Tissue Sarcoma Recruiting NCT01532687 Phase 2 Gemcitabine Hydrochloride;Pazopanib Hydrochloride
42 A Study of Bevacizumab in Combination With Chemotherapy for Treatment of Osteosarcoma Active, not recruiting NCT00667342 Phase 2 Cisplatin;Doxorubicin;Methotrexate;Ifosfamide;etoposide
43 To Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors Active, not recruiting NCT01962103 Phase 1, Phase 2 nab-paclitaxel
44 Alisertib in Treating Patients With Advanced or Metastatic Sarcoma Active, not recruiting NCT01653028 Phase 2 Alisertib
45 Pembrolizumab and Gemcitabine Chemotherapy in Leiomyosarcoma and Undifferentiated Pleomorphic Sarcoma Not yet recruiting NCT03123276 Phase 1, Phase 2 Pembrolizumab;Gemcitabine
46 Talimogene Laherparepvec and Radiation Therapy in Treating Patients With Newly Diagnosed Soft Tissue Sarcoma That Can Be Removed by Surgery Suspended NCT02923778 Phase 2
47 Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma Suspended NCT02601209 Phase 1, Phase 2 Pazopanib Hydrochloride;Sapanisertib
48 Gemcitabine and Docetaxel in Combination With Pazopanib (Gem/Doce/Pzb) for the Neoadjuvant Treatment of Soft Tissue Sarcoma (STS) Terminated NCT01418001 Phase 1, Phase 2 Gemcitabine and Docetaxel in Combination with Pazopanib
49 Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Stage IB, Stage II, or Stage III Soft Tissue Sarcoma Terminated NCT00740597 Phase 2
50 Celecoxib and Radiation Therapy in Treating Patients With Stage II or Stage III Soft Tissue Sarcoma of the Arm, Hand, Leg, or Foot That Has Been Removed by Surgery Completed NCT00450736 Phase 1 celecoxib

Search NIH Clinical Center for Histiocytoma

Cochrane evidence based reviews: histiocytoma

Genetic Tests for Histiocytoma

Genetic tests related to Histiocytoma:

id Genetic test Affiliating Genes
1 Histiocytoma 29

Anatomical Context for Histiocytoma

MalaCards organs/tissues related to Histiocytoma:

39
Bone, Lung, Skin, Liver, Heart, Colon, Brain

Publications for Histiocytoma

Articles related to Histiocytoma:

(show top 50) (show all 909)
id Title Authors Year
1
A Rare Case of Malignant Fibrous Histiocytoma (Undifferentiated High-Grade Pleomorphic Sarcoma) of Malar Region. ( 28468216 )
2017
2
Deep Benign Fibrous Histiocytoma of the Anterior Mediastinum Mimicking Malignancy. ( 28497381 )
2017
3
Pathologically Benign Lymph Nodes Can Mimic Malignancy on Imaging in Patients With Angiomatoid Fibrous Histiocytoma. ( 28536856 )
2017
4
CORR Insights(Ar): Pathologically Benign Lymph Nodes Can Mimic Malignancy on Imaging in Patients With Angiomatoid Fibrous Histiocytoma. ( 28656494 )
2017
5
Cholesterotic fibrous histiocytoma with no associated dyslipidemia. ( 28303567 )
2017
6
Malignant fibrous histiocytoma arising from renal capsule: An extremely rare entity. ( 28937382 )
2017
7
Dermoscopy and reflectance confocal microscopy of osteoclastic deep benign fibrous histiocytoma. ( 28895663 )
2017
8
Two cases of benign fibrous histiocytomas (dermatofibromas) associated with Langerhans cell histiocytosis. ( 28941307 )
2017
9
Intracranial myxoid mesenchymal tumors with EWSR1-CREB family gene fusions: myxoid variant of angiomatoid fibrous histiocytoma or novel entity? ( 28281318 )
2017
10
Treatment outcomes of malignant fibrous histiocytoma of the maxillary sinus. ( 28901310 )
2017
11
18F-FDG Uptake in Benign Fibrous Histiocytoma of Adrenal Gland: A Potential Pitfall. ( 28632691 )
2017
12
TLE-1-Positive Angiomatoid Fibrous Histiocytoma Mimicking Synovial Sarcoma. ( 28248724 )
2017
13
Benign Fibrous Histiocytoma: An Uncommon Presentation. ( 28892910 )
2017
14
Primary pulmonary malignant fibrous histiocytoma: case report and literature review. ( 28932590 )
2017
15
Aneurysmal Variant of Fibrous Histiocytoma- A Rare Entity Known for Recurrence. ( 28764178 )
2017
16
Angiomatoid fibrous histiocytoma of the scalp mimicking cutaneous angiosarcoma in incisional biopsy containing CD31-positive histiocytes: A potential histopathological pitfall. ( 28370384 )
2017
17
Primary hepatic malignant fibrous histiocytoma combined with invasion of inferior vena cava: A case report and literature review. ( 28591058 )
2017
18
Malignant fibrous histiocytoma masquerading as pyogenic granuloma. ( 28388346 )
2017
19
Aneurysmal fibrous histiocytoma - spindle cell tumour with pigment: A diagnostic dilemma on cytology. ( 28727241 )
2017
20
Angiomatoid fibrous histiocytoma: Clinicopathological spectrum of five cases, including EWSR1-CREB1 positive result in a single case. ( 27166030 )
2016
21
Intraspinal extradural benign fibrous histiocytoma of the lumbar spine in a pediatric patient. Case report and literature review. ( 26984808 )
2016
22
Benign Fibrous Histiocytoma of the Frontal Bone. ( 27054431 )
2016
23
Malignant fibrous histiocytoma of the skin. A case treated with radiotherapy. ( 26837483 )
2016
24
Primary malignant fibrous histiocytoma of the liver. ( 27826563 )
2016
25
Primary malignant fibrous histiocytoma of the colon: A case report and review of the literature. ( 27284436 )
2016
26
Benign Fibrous Histiocytoma: A Rare Case Report and Literature Review. ( 26929563 )
2016
27
Angiomatoid fibrous histiocytoma: A case of local recurrence and metastases to loco-regional lymph nodes that responded to chemotherapy. ( 28012233 )
2016
28
An unresectable retroperitoneal malignant fibrous histiocytoma: A case report. ( 27073487 )
2016
29
A case of recurrent malignant fibrous histiocytoma of the mesentery. ( 27351621 )
2016
30
Benign Fibrous Histiocytoma of Mandible: A Case Report and Updated Review. ( 27504429 )
2016
31
Successful treatment of advanced malignant fibrous histiocytoma of the right forearm with apatinib: a case report. ( 26917971 )
2016
32
'Pure' spindle cell variant of angiomatoid fibrous histiocytoma, lacking classic histologic features. ( 27637157 )
2016
33
Primary malignant fibrous histiocytoma of long bones: long-term follow-up. ( 27499321 )
2016
34
ALK Rearrangement and Overexpression in an Unusual Cutaneous Epithelioid Tumor With a Peculiar Whorled "Perineurioma-like" Growth Pattern: Epithelioid Fibrous Histiocytoma. ( 27438515 )
2016
35
Double primary malignant fibrous histiocytoma and squamous cell carcinoma of the larynx treated with laser laryngeal conservation surgery. ( 27170836 )
2016
36
Subcutaneous Benign Fibrous Histiocytoma: Rare Presentation on Cheek-Case Report and Review of Literature. ( 27408454 )
2016
37
Malignant fibrous histiocytoma of the skin: a case treated with radiotherapy. ( 27176091 )
2016
38
Fibrous Histiocytoma of the Conjunctiva. ( 27636240 )
2016
39
Angiomatoid fibrous histiocytoma: novel MR imaging findings. ( 26919861 )
2016
40
Deep Penetrating Fibrous Histiocytoma: A Case Report and Implications for Surgical Management. ( 26999346 )
2016
41
Intracranial Angiomatoid Fibrous Histiocytoma: Case Report and Literature Review. ( 27667574 )
2016
42
Retrospective characterisation of solitary cutaneous histiocytoma with lymph node metastasis in eight dogs. ( 27486860 )
2016
43
Primary Angiomatoid Fibrous Histiocytoma of the Lung with Mediastinal Lymph Node Metastasis. ( 27544801 )
2016
44
Computed tomography and magnetic resonance imaging findings of malignant fibrous histiocytoma of the head and neck. ( 27123302 )
2016
45
Conjunctival fibrous histiocytoma in an 8-year-old boy. ( 27282913 )
2016
46
Malignant Fibrous Histiocytoma of the Testicular Appendages Mimicking an Obstructed Hernia in an Elderly Man: Case Report and Review of the Literature. ( 26953736 )
2016
47
14-Year-Old Boy With Mild Antecedent Neck Pain in Setting of Acute Trauma: A Rare Case of Benign Fibrous Histiocytoma of the Spine. ( 26991583 )
2016
48
Reconstruction of the elbow by Baksi sloppy hinge total elbow prosthesis following excision of a malignant fibrous histiocytoma. ( 26566346 )
2015
49
Malignant fibrous histiocytoma of maxillary sinus- a diagnostic challenge. ( 27217674 )
2015
50
Metastatic Malignant Fibrous Histiocytoma in the Stomach: Imaging With 18F-FDG PET/CT. ( 26053714 )
2015

Variations for Histiocytoma

Expression for Histiocytoma

Search GEO for disease gene expression data for Histiocytoma.

Pathways for Histiocytoma

Pathways related to Histiocytoma according to GeneCards Suite gene sharing:

(show all 24)
id Super pathways Score Top Affiliating Genes
1 12.53 CDK4 CREB1 KIT MDM2 TP53
2
Show member pathways
12.42 CDK4 CREB1 MDM2 TP53
3 12.23 ATF1 CDK4 CREB1 TP53
4
Show member pathways
12.12 CDK4 CREB1 MDM2 TP53
5
Show member pathways
12.1 CDK4 CREB1 MDM2 TP53
6 12.04 CDK4 CREB1 MDM2 TP53
7 11.86 CD163 KIT PTPRC
8 11.81 CDK4 MDM2 TP53
9 11.81 ATF1 EWSR1 FUS MDM2 TP53
10 11.74 ATF1 CREB1 MYOD1
11 11.73 KIT MYOD1 PTPRC
12 11.68 CDK4 MDM2 TP53
13
Show member pathways
11.66 CREB1 MDM2 TP53
14 11.63 CREB1 MDM2 TP53
15 11.57 CDK4 CREB1 MYOD1
16 11.55 CD163 KIT PTPRC
17 11.54 ATF1 CDK4 CREB1 MDM2 TP53
18 11.52 CDK4 MDM2 TP53
19 11.31 CREB1 MDM2 TP53
20 11.19 CDK4 MDM2 TP53
21 11.04 ATF1 CREB1 TP53
22 10.94 CDK4 MDM2 TP53
23 10.9 ATF1 CREB1
24 10.59 ATF1 CDK4 MDM2 TP53

GO Terms for Histiocytoma

Cellular components related to Histiocytoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 transcription factor complex GO:0005667 8.92 ATF1 CDK4 CREB1 MYOD1

Biological processes related to Histiocytoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 positive regulation of protein export from nucleus GO:0046827 8.96 MDM2 TP53
2 cellular response to actinomycin D GO:0072717 8.62 MDM2 TP53

Molecular functions related to Histiocytoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 enzyme binding GO:0019899 9.46 CREB1 MDM2 MYOD1 TP53
2 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding GO:0003705 9.13 ATF1 CREB1 MYOD1
3 identical protein binding GO:0042802 9.02 CREB1 EWSR1 FUS MDM2 TP53

Sources for Histiocytoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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