MCID: HST011
MIFTS: 54

Histoplasmosis malady

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Histoplasmosis

About this section
Sources:
11Disease Ontology, 46NIH Rare Diseases, 13DISEASES, 52Orphanet, 48Novoseek, 36MedlinePlus, 2CDC, 37MeSH, 66UMLS, 28ICD10, 30ICD9CM, 43NCIt, 38MESH via Orphanet, 67UMLS via Orphanet, 29ICD10 via Orphanet, 60SNOMED-CT, 62The Human Phenotype Ontology
See all MalaCards sources

Aliases & Descriptions for Histoplasmosis:

Name: Histoplasmosis 11 13 52 36 2 37 66
Reticuloendotheliosis, X-Linked 46 37 66
Reticuloendotheliosis 11 46 48
 
Infection by Histoplasma Capsulatum 66
Reticuloendothelial Hyperplasia 11
Darling Disease 52

Characteristics:

HPO:

62
Inheritance: x-linked inheritance
Onset and clinical course: infantile onset


Classifications:



External Ids:

Disease Ontology11 DOID:1731
ICD1028 B39, B39.9, B39.4
ICD9CM30 115, 115.9
Orphanet52 ORPHA390
MESH via Orphanet38 D006660
UMLS via Orphanet67 C0019655, C0153261
ICD10 via Orphanet29 B39.0, B39.1, B39.2 B39.3, B39.4, B39.5, B39.9, more

Summaries for Histoplasmosis

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MedlinePlus:36 Histoplasmosis is a disease caused by a fungus (or mold) called histoplasma. the fungus is common in the eastern and central united states. it grows in soil and material contaminated with bat or bird droppings. you get infected by breathing the fungal spores. you cannot get the infection from someone else. histoplasmosis is often mild, with no symptoms. if you do get sick, it usually affects your lungs. symptoms include feeling ill, fever, chest pains, and a dry cough. in severe cases, histoplasmosis spreads to other organs. this is called disseminated disease. it is more common in infants, young children, seniors, and people with immune system problems. your doctor might do a variety of tests to make the diagnosis, including a chest x-ray, ct scan of the lungs, or examining blood, urine, or tissues for signs of the fungus. mild cases usually get better without treatment. treatment of severe or chronic cases is with antifungal drugs. centers for disease control and prevention

MalaCards based summary: Histoplasmosis, also known as reticuloendotheliosis, x-linked, is related to panuveitis and hemophagocytic lymphohistiocytosis, and has symptoms including nonproductive cough, headache and loss of appetite. An important gene associated with Histoplasmosis is HLA-B (Major Histocompatibility Complex, Class I, B), and among its related pathways are Antigen Presentation- Folding, assembly and peptide loading of class I MHC and Cytokines and Inflammatory Response. The drugs fluconazole and ketoconazole have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and colon.

Disease Ontology:11 A primary systemic mycosis that results in systemic fungal infection, has material basis in histoplasma capsulatum var capsulatum or has material basis in histoplasma capsulatum var duboisii, transmitted by airborne spores and has symptom nonproductive cough, has symptom headache, has symptom loss of appetite and has symptom muscle pains.

CDC:2 Histoplasmosis is an infection caused by a fungus called Histoplasma. The fungus lives in the environment, particularly in soil that contains large amounts of bird or bat droppings. In the United States, Histoplasma mainly lives in the central and eastern states, especially areas around the Ohio and Mississippi River valleys. The fungus also lives in parts of Central and South America, Africa, Asia, and Australia.

Wikipedia:69 Histoplasmosis (also known as \"Cave disease,\" \"Darling\'s disease,\" \"Ohio valley disease,\"... more...

Related Diseases for Histoplasmosis

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Diseases related to Histoplasmosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 225)
idRelated DiseaseScoreTop Affiliating Genes
1panuveitis30.4HLA-DQA1, HLA-DRB1
2hemophagocytic lymphohistiocytosis30.0HLA-A, HLA-B, HLA-DRB1, IFNG
3arachnoiditis30.0HLA-A, HLA-B, HLA-DRB1
4rheumatoid arthritis29.5HLA-B, HLA-DQA1, HLA-DRB1, IFNG
5systemic lupus erythematosus29.1C3, HLA-DQA1, HLA-DRB1, IFNG
6african histoplasmosis12.2
7american histoplasmosis12.2
8histoplasmosis pericarditis12.1
9intrapelvic lymph node leukemic reticuloendotheliosis12.0
10histoplasmosis retinitis12.0
11histoplasmosis meningitis12.0
12branch retinal artery occlusion10.7HLA-A, HLA-B
13gonococcal iridocyclitis10.7HLA-A, HLA-B
14antigen-peptide-transporter 2 deficiency10.7HLA-A, HLA-B
15thrombotic thrombocytopenic purpura10.7HLA-A, HLA-B
16blastomycosis10.7
17human herpesvirus 810.7HLA-A, HLA-B
18common variable immunodeficiency10.7HLA-B, HLA-DRB1
19vitreoretinochoroidopathy dominant10.7HLA-B, HLA-DRB1
20epstein-barr virus hepatitis10.6HLA-B, HLA-DRB1
21wolffian duct adenocarcinoma10.6HLA-DQA1, HLA-DRB1
22parsonage turner syndrome10.6HLA-DQA1, HLA-DRB1
23myopathy-growth delay-intellectual disability-hypospadias syndrome10.6HLA-DQA1, HLA-DRB1
24selective igm deficiency disease10.6HLA-B, HLA-DQA1
25tertiary neurosyphilis10.6HLA-DQA1, IFNG
26childhood pilocytic astrocytoma10.6HLA-A, TF
27x-linked congenital generalized hypertrichosis10.6HLA-B, HLA-DRB1
28autoinflammation, lipodystrophy, and dermatosis syndrome10.6HLA-DQA1, HLA-DRB1
29anthracosilicosis10.6HLA-DRB1, IFNG
30chronic hiccups10.6IFNG, MICA
31hypertrophy of breast10.5HLA-A, HLA-B
32fibrosing mediastinitis10.5
33oculogyric crisis10.5HLA-DQA1, HLA-DRB1
34lymphocytic colitis10.5HLA-DRB1, IFNG
35chronic polyneuropathy10.5HLA-DRB1, IFNG
36orbit alveolar rhabdomyosarcoma10.5HLA-DRB1, IFNG
37progressive locomotor ataxia10.4HLA-A, HLA-B, HLA-DRB1
38mitochondrial encephalomyopathy10.4HLA-A, HLA-B, HLA-DRB1
39hypercementosis10.4HLA-A, HLA-B, HLA-DRB1
40foster-kennedy syndrome10.4HLA-A, HLA-B, HLA-DRB1
41collagen disease10.4HLA-B, IFNG
42potato nose10.4HLA-A, HLA-B, HLA-DRB1
43hemochromatosis10.4C3, HLA-DRB1
44ovarian papillary cystadenoma10.4HLA-B, HLA-DQA1, HLA-DRB1
45cirrhotic cardiomyopathy10.4HLA-A, HLA-B, HLA-DRB1
46conjunctival pigmentation10.4HLA-A, HLA-B, HLA-DRB1
47breast carcinoma in situ10.4HLA-A, HLA-B, HLA-DRB1
48mastocytosis cutaneous with short stature conductive hearing loss and microtia10.4HLA-DRB1, IFNG
49allergic hypersensitivity disease10.4HLA-B, HLA-DRB1
50gastric dilatation10.4HLA-A, HLA-B, IFNG

Graphical network of the top 20 diseases related to Histoplasmosis:



Diseases related to histoplasmosis

Symptoms for Histoplasmosis

About this section

Symptoms:

 11
  • n
  • h
  • l
  • m

HPO human phenotypes related to Histoplasmosis:

id Description Frequency HPO Source Accession
1 jaundice HP:0000952
2 hepatosplenomegaly HP:0001433
3 anemia HP:0001903
4 lymphadenopathy HP:0002716

UMLS symptoms related to Histoplasmosis:


pruritus

Drugs & Therapeutics for Histoplasmosis

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Drugs for Histoplasmosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
BevacizumabPhase 4, Phase 31938216974-75-3
Synonyms:
216974-75-3
Avastin
Avastin (TN)
Bevacizumab
Bevacizumab (genetical recombination)
 
Bevacizumab (genetical recombination) (JAN)
D06409
R-435
anti-VEGF monoclonal antibody
antiVEGF
bevacizumab
2
VoriconazolePhase 4127137234-62-971616
Synonyms:
(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol
(2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
(AlphaR,betas)-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol
(R-(R*,S*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol
(R-(R*,s*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol
(alphaR,betaS)-alpha-(2,4-Difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol
(alphaR,betaS)-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol
137234-62-9
173967-54-9
AC-823
AC1L2GHR
AC1Q4O6I
AKOS005145705
C07622
C102790
CHEBI:10023
CHEMBL638
CID71616
CPD000466350
D00578
DB00582
DRG-0301
FT-0082604
HMS2051N09
LS-181799
 
MLS000759464
MLS001424082
MolPort-003-850-863
Pfizer brand of voriconazole
S1442_Selleck
SAM001246664
SMR000466350
TL8000858
UK 109,496
UK 109496
UK-109,496
UK-109496
UNII-JFU09I87TR
VCZ
VRC
Vfend
Vfend (TN)
Vfend, Voriconazole
Voriconazol
Voriconazole
Voriconazole (JAN/USAN/INN)
Voriconazole [USAN:INN:BAN]
Voriconazole in combination with MGCD290
Voriconazolum
ZINC00014864
voriconazole
3
MiconazolePhase 4, Phase 3, Phase 2, Phase 1, Phase 0357322916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
4
ClotrimazolePhase 33323593-75-12812
Synonyms:
(Chlorotrityl)imidazole
1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazole
1-(O-Chloro-alpha,alpha-diphenylbenzyl)imidazole
1-(O-Chlorotrityl)imidazole
1-(alpha-(2-Chlorophenyl)benzhydryl)imidazole
1-(o-Chloro-α,α-diphenylbenzyl)imidazole
1-(o-Chlorotrityl)imidazole
1-(α-(2-Chlorophenyl)benzhydryl)imidazole
117829-71-7
23593-75-1
33894_FLUKA
33894_RIEDEL
3ACDFDF8-38E3-4368-85D0-BDF8AE1E6591
AB00051951
AC-279
AC1L1EIW
B 5097
BAY 5097
BAY b 5097
BAY b5097
BAY-5097
BAYb 5097
BIDD:GT0450
BIDD:PXR0036
BPBio1_000126
BRN 0622318
BSPBio_000114
BSPBio_002057
Bay b 9057
Bay-B 5097
Bayer Brand 1 of Clotrimazole
Bayer Brand 2 of Clotrimazole
Bio-0442
C 6019
C06922
C22H17ClN2
C6019_SIGMA
CAS-23593-75-1
CCRIS 6245
CHEBI:3764
CHEMBL104
CID2812
CPD-8926
CPD000058306
Canesten
Canesten 1-Day Cream Combi-Pak
Canesten 1-Day Therapy
Canesten 3-Day Therapy
Canesten 6-Day Therapy
Canesten Combi-Pak 1-Day Therapy
Canesten Combi-Pak 3-Day Therapy
Canesten Cream
Canesten Solution
Canestene
Canestine
Canifug
Chlotrimazole
Cimitidine
Clomatin
Clotrimaderm
Clotrimaderm Cream
Clotrimazol
Clotrimazol [INN-Spanish]
Clotrimazole
Clotrimazole (JP15/USP/INN)
Clotrimazole Schering Brand
Clotrimazole [USAN:INN:BAN:JAN]
Clotrimazolum
Clotrimazolum [INN-Latin]
Cutistad
D00282
D003022
DB00257
DRG-0072
Desamix F
DivK1c_000665
EINECS 245-764-8
EU-0100315
Empecid
Esparol
FB 5097
FB b 5097
Fem Care
FemCare
Gino-Lotremine
Gyne lotrimin
Gyne-Lotrimin
Gyne-Lotrimin 3
Gyne-Lotrimin 3 Combination Pack
Gyne-Lotrimin Combination Pack
Gyne-Lotrimin3
Gyne-Lotrimin3 Combination Pack
Gyne-lotrimin
Gynix
HMS1568F16
HMS1920O21
HMS2051E11
HMS2091G10
HMS502B07
HSDB 3266
I01-3474
IDI1_000665
 
KBio1_000665
KBio2_001823
KBio2_004391
KBio2_006959
KBio3_001277
KBioGR_000850
KBioSS_001823
Kanesten
Klotrimazole
LS-78271
Lopac-C-6019
Lopac0_000315
Lotrimax
Lotrimin
Lotrimin (TN)
Lotrimin (tn)
Lotrimin AF
Lotrimin AF Cream
Lotrimin AF Jock-Itch Cream
Lotrimin AF Lotion
Lotrimin AF Solution
Lotrimin Af
Lotrimin Cream
Lotrimin Lotion
Lotrimin Solution
Lotrisone
MLS000028502
MLS000758243
MLS001423972
MolPort-002-557-756
Mono-baycuten
Monobaycuten
Mycelax
Mycelex
Mycelex (TN)
Mycelex (tn)
Mycelex 7
Mycelex Cream
Mycelex G
Mycelex OTC
Mycelex Solution
Mycelex Troches
Mycelex Twin Pack
Mycelex-7
Mycelex-7 Combination Pack
Mycelex-G
Mycelex: MycosporinRimazole
Myclo Cream
Myclo Solution
Myclo Spray Solution
Myclo-Gyne
Mycofug
Mycosporin
Mykosporin
NCGC00015251-01
NCGC00015251-02
NCGC00015251-03
NCGC00015251-09
NCGC00093761-01
NCGC00093761-02
NCGC00093761-03
NCGC00093761-04
NCGC00093761-05
NCGC00093761-06
NCIMech_000609
NINDS_000665
NSC 257473
NSC257473
Nalbix
Neo-Zol Cream
Otomax
Pan-Fungex
Pedisafe
Prestwick0_000267
Prestwick1_000267
Prestwick2_000267
Prestwick3_000267
Prestwick_120
QTL1_000024
Rimazole
S1606_Selleck
SAM001247056
SMR000058306
SPBio_000176
SPBio_002333
SPECTRUM1500200
STK700023
Schering Brand of Clotrimazole
Spectrum2_000128
Spectrum3_000359
Spectrum4_000295
Spectrum5_000781
Spectrum_001343
Stiemazol
Tibatin
Trimysten
Trivagizole 3
UNII-G07GZ97H65
Veltrim
ZINC03807804
clotrimazole
clotrimeizol
nchembio.65-comp9
nchembio790-comp30
5
FluconazolePhase 3, Phase 217386386-73-43365
Synonyms:
2,4-Difluoro-alpha,alpha-bis(1H-1,2,4-triazol-1-ylmethyl)benzyl alcohol
2,4-difluoro-,1-bis(1H-1,2,4-triazol-1-ylmethyl)benzyl alcohol
2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL
2-(2,4-DIFLUOROPHENYL)-1,3-di(1H-1,2,4-triazol-1-yl)propan-2-ol
2-(2,4-Difluoro-phenyl)-1,3-bis-[1,2,4]triazol-1-yl-propan-2-ol
2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)-2-propanol
2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol
2-(2,4-Difluorophenyl)-1,3-di-1H-1,2,4-triazol-1-ylpropan-2-ol
2-(2,4-difluorophenyl)-1,3-bis(1,2,4-triazol-1-yl)propan-2-ol
86386-73-4
AC-428
AC1L1FRQ
AC1Q77FV
AKOS000280854
AbZ Brand of Fluconazole
Afungil
Alflucoz
Aliud Brand of Fluconazole
Alpharma Brand of Fluconazole
Apo Fluconazole
Apo-Fluconazole
Apotex Brand of Fluconazole
Armstrong Brand of Fluconazole
BIDD:GT0799
BRD-K05977355-001-02-6
BSPBio_003504
Baten
Beagyne
Bio-0041
Biocanol
Biozole
Biozolene
C13H12F2N6O
CCRIS 7211
CHEBI:46081
CHEMBL106
CID3365
CPD000471882
Canzol
Chemia Brand of Fluconazole
Cryptal
D00322
D015725
DB00196
DIFLUCAN IN DEXTROSE 5% IN PLASTIC CONTAINER
DIFLUCAN IN SODIUM CHLORIDE 0.9%
DIFLUCAN IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
DRG-0005
Diflazon
Diflucan
Diflucan (TN)
Diflucan, Trican, Alfumet, Fluconazole
Dimycon
DivK1c_001030
Effik Brand of Fluconazole
Elazor
F0677
F8929_SIGMA
FCZ
FLCZ
Fluc Hexal
Flucazol
FlucoLich
Flucobeta
Fluconazol
Fluconazol AL
Fluconazol AbZ
Fluconazol Isis
Fluconazol Stada
Fluconazol [Spanish]
Fluconazol ratiopharm
Fluconazol von ct
Fluconazol-Isis
Fluconazol-ratiopharm
Fluconazole & Bovine Lactoferrin
Fluconazole & Human recombinant granulocyte colony stimulating factor
Fluconazole & MC-510,011
Fluconazole & hGCSF
Fluconazole (JAN/USAN/INN)
Fluconazole [USAN:INN:BAN:JAN]
Fluconazole in combination with MGCD290
Fluconazole in dextrose 5% in plastic container
Fluconazole in sodium chloride 0.9%
Fluconazole in sodium chloride 0.9% in plastic container
Fluconazolum
Fluconazolum [Latin]
Flucostat
 
Flucytosine & Nyotran
Flucytosine & Nyotran(Liposomal Nystatin)
Flukezol
Flunazul
Flunizol
Fluzone
Forcan
Fuconal
Fungata
GL663142 & Fluconazole
HMS1922O10
HMS2090I20
HMS2093M21
HMS503M21
HSDB 7420
Hexal Brand of Fluconazole
I06-0069
IDI1_001030
KBio1_001030
KBio2_002134
KBio2_004702
KBio2_007270
KBio3_003009
KBioGR_000360
KBioSS_002134
KS-1059
LS-1858
Lavisa
Lesvi Brand of Fluconazole
Lichtenstein Brand of Fluconazole
Loitin
MLS001066394
MLS001165780
MLS001195645
MLS001304713
MLS001306492
Mack Brand of Fluconazole
MolPort-000-883-859
MolPort-002-885-825
Mutum
NCGC00095089-01
NCGC00095089-02
NCGC00095089-04
NCGC00095089-05
NINDS_001030
Neofomiral
Oxifugol
Oxifungol
Pfizer Brand of Fluconazole
Pfleger Brand of Fluconazole
Pritenzol
S1331_Selleck
SAM002589905
SAT Brand of Fluconazole
SMR000471882
SPBio_001613
SPECTRUM1503975
STK619301
Silanes Brand of Fluconazole
Solacap
Spectrum2_001607
Spectrum3_001912
Spectrum4_000090
Spectrum5_001277
Spectrum_001654
Stada Brand of Fluconazole
Syscan
TL8005609
TPF
Triflucan
UK 49858
UK-49858
UK49858
UNII-8VZV102JFY
Vita Brand of Fluconazole
XMP.284 & Fluconazole
XMP.366 & Fluconazole
XMP.391 & Fluconazole
ZINC00004009
Zemyc
Zoltec
Zonal
betapharm Brand of Fluconazole
ct Arzneimittel Brand of Fluconazole
ct-Arzneimittel Brand of Fluconazole
fluconazole
nchembio.100-comp3
nchembio.65-comp15
ratiopharm Brand of Fluconazole
6
ItraconazolePhase 3, Phase 2, Phase 1, Phase 014584625-61-655283
Synonyms:
(+-)-1-sec-Butyl-4-(p-(4-(p-(((2R*,4S*)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-delta(sup 2)-1,2,4-triazolin-5-one
(+/-)-1-[( R *)- sec -butyl]-4-[ p -[4-[ p -[[(2 R *,4 S *)-2-(2,4-dichlorophenyl)-2-(1 H -1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-(DELTA) 2 1,2,4-triazolin-5-one mixture with (+/-)-1-[( R *)- sec -butyl]-4-[ p -[4- [ p -[[(2 S *,4 R *)-2-(2,4-dichlorophenyl)-2-(1 H -1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl] phenyl]-(DELTA) 2 -1,2,4-triazolin-5-one
(1)-cis-4-(4-(4-(4-((2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2,4-dihydro-2-sec-butyl-3H-1,2,4-triazol-3-one
2-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one
2-butan-2-yl-4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one
2-butan-2-yl-4-[4-[4-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one
2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one
3H-1,2,4-Triazol-3-one, 4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-pipera-zinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)
4-(4-{4-[4-({[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl}oxy)phenyl]piperazin-1-yl}phenyl)-2-(1-methylpropyl)-2,4-dihydro-3H-1,2,4-triazol-3-one
84604-65-9
84625-61-6
AC-542
AC1L1GQ5
AC1L1IRU
AC1OCEL7
AC1Q6EZ3
AKOS000280875
Ambap84625-61-6
BIDD:GT0796
BRN 6042047
C35H38Cl2N8O4
CHEBI:6076
CHEMBL22587
CHEMBL882
CID3793
CID55283
CID6917738
CID9961741
CPD000058959
Canadiol
D00350
DB01167
EINECS 283-347-2
FT-0082511
HMS2051K14
HMS2090M20
Hyphanox
I01-1043
I0732
ITC
ITCZ
ITZ
Intraconazole
 
Itraconazol
Itraconazol [Spanish]
Itraconazole
Itraconazole & Bovine Lactoferrin
Itraconazole & Nyotran
Itraconazole & Nyotran(Liposomal Nystatin)
Itraconazole (JAN/USAN)
Itraconazole [USAN:BAN:INN:JAN]
Itraconazole oral solution
Itraconazolum
Itraconazolum [Latin]
Itrizole
Itrizole (TN)
Itrizole (tn)
LS-1843
MLS000028582
MLS000759472
MLS000863291
MLS001148245
MolPort-000-883-864
MolPort-003-848-295
NCGC00089812-03
Oriconazole
Oriconazole, R51211, Sporanox
Orungal
Prokanazol
R 51211
R-51211
S2476_Selleck
SAM001246679
SMR000058959
Sempera
Spherazole
Sporal
Sporanos
Sporanox
Sporanox (TN)
Sporanox (tn)
Sporonox
TL8005525
Triasporn
UNII-304NUG5GF4
cis-Itraconazole
itraconazole
7hydroxyitraconazolePhase 3, Phase 2, Phase 1, Phase 0145
8
Amphotericin BPhase 31171397-89-314956, 5280965
Synonyms:
12633-72-6
1397-89-3
30782-62-8
5-18-10-00525 (Beilstein Handbook Reference)
54482-28-9
8055-20-7
AB00513832
ABLC
AC1L1CN2
AC1L24V6
AC1L70KF
AC1L73U6
AC1NQXTD
AC1NTQ32
AC1NUQG4
AC1NY9JC
AC1O7GCZ
AC1O8FQV
AC1O8PFK
AI3-26528
AMPH-B
AMPH-b
Abelcet
Abelecet
AmBisome (TN)
Ambap1397-89-3
Ambisome
Amfotericina B
Amfotericina B [INN-Spanish]
Ampho-Moronal
Amphocin
Amphomoronal
Amphortericin B
Amphotec
Amphotec (TN)
Amphotericin
Amphotericin .BETA.
Amphotericin B
Amphotericin B (JP15/USP/INN)
Amphotericin B Cholesterol Dispersion
Amphotericin B Colloidal Dispersion
Amphotericin B [USAN:INN:JAN]
Amphotericin B, Lipid-based
Amphotericin B, Streptomyces sp.
Amphotericin-B
Amphotericine B
Amphotericine B [INN-French]
Amphotericinum
Amphotericinum B
Amphotericinum B [INN-Latin]
Amphotherizin
Amphotherizin [German]
Amphotéricine B
Amphozone
BIDD:GT0351
BPBio1_000374
BRN 0078342
BSPBio_000340
C-AmB
C06573
C47H73NO17
CCRIS 5963
CHEBI:2682
CHEMBL1200646
CHEMBL267345
CID10533925
CID10629638
CID10677275
CID14956
CID1972
 
CID352546
CID354192
CID5280965
CID5386092
CID5458486
CID5771695
CID6604295
CID6708817
CID6713692
CID9919339
D00203
DB00681
DivK1c_007045
EINECS 215-742-2
Fungilin
Fungisome
Fungisone
Fungizone
Fungizone (TN)
HMS1569A22
HSDB 3008
HSDB 3008 IAB
Halizon
I06-0257
KBio1_001989
KBio2_000551
KBio2_003119
KBio2_005687
KBioGR_002298
KBioSS_000551
LMPK06000002
LNS-AmB
LS-187721
LS-93
Liposomal Amphotericin B
Liposomal amphotericin b
MLS002702966
MolPort-006-392-260
Mysteclin-F
NCGC00014913
NCGC00090808-01
NCGC00098014-01
NCGC00179595-01
NCI527017
NCI60_004288
NCIStruc1_001042
NCIStruc2_000920
NKTR-024
NS 718
NSC 527017
NSC-527017
NSC527017
Prestwick0_000410
Prestwick1_000410
Prestwick2_000410
Prestwick3_000410
Prestwick_721
SMP1_000302
SMR001566780
SPBio_000715
SPBio_002279
ST50999656
SinuNase
SpecPlus_000949
Spectrum2_000818
Spectrum4_001779
Spectrum_000111
UNII-7XU7A7DROE
amophotericin B
amphotericin B liposomal
amphotericin b
9
VerteporfinPhase 286129497-78-5
Synonyms:
Verteporfin
 
Verteporfina
Verteporfinum
Vertéporfine
10
RanibizumabPhase 2, Phase 1469347396-82-1459903
Synonyms:
347396-82-1
D05697
Lucentis
Lucentis (TN)
 
Ranibizumab
Ranibizumab (USAN/INN)
Ranibizumab (genetical recombination)
Ranibizumab (genetical recombination) (JAN)
ranibizumab
rhuFab V2
11
KetoconazolePhase 117465277-42-147576, 3823
Synonyms:
(+)-Ketoconazole
(+-)-cis-1-Acetyl-4-(p-((2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine
(+-)-cis-1-acetyl-4-(p-((2-(2,4-dichlorophenyl)-2-(imidazol-1- ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazine
(+/-)-cis-1-Acetyl-4-(4-[(2-[2,4-dichlorophenyl]-2-[1H-imidazol-1-ylmethyl]-1,3-dioxolan-4-yl)-methoxy]phenyl)piperazine
(+/-)-cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine
1-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethanone
1-acetyl-4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine
65277-42-1
79156-75-5
AC-15957
AC1L9UG3
BIDD:GT0696
BIM-0050645.0001
BPBio1_000635
BRD-K29113274-001-03-6
BRN 4303081
BSPBio_000577
C26H28Cl2N4O4
CHEBI:48336
CHEMBL75
CID456201
CIS-1-ACETYL-4-(4-((2-(2,4-DICHLOROPHENYL)-2-(1H-IMIDAZOL-1-YLMETHYL)-1,3-DIOXOLAN-4-YL)METHOXY)PHENYL)PIPERAZINE
CPD000058460
EINECS 265-667-4
EU-0100666
Extina
Fungarest
Fungoral
HMS1569M19
HMS2051A19
HMS2089N05
HSDB 7447
K 1003
K0045
K1003_SIGMA
KCZ
KS-1205
KTZ
KW-1414
KZ
Ketoconazol
Ketoconazole
Ketoconazole [USAN:INN:BAN:JAN]
Ketoconazolum
Ketoderm
Ketoisdin
Ketozole
 
LS-110149
Lopac0_000666
MLS000069784
MLS000758224
MLS001146934
MLS002207053
MLS002222255
MolPort-003-848-307
NCGC00025000-01
NCGC00025000-02
NCGC00025000-03
NCGC00025000-04
NCGC00025000-05
NCGC00025000-06
NCGC00025000-07
NCGC00025000-08
NCGC00025000-09
NSC 317629
NSC317629
Nizoral
Nizoral a-D
Nizoral, Extina, Xolegel, Kuric, Ketoconazole
Orifungal M
Panfungol
Piperazine
Prestwick0_000389
Prestwick1_000389
Prestwick2_000389
Prestwick3_000389
Prestwick_744
R 41,400
R 41400
R-41400
R41,400
R41400
S1353_Selleck
SAM001246983
SMR000058460
SPBio_002498
Tocris-1103
UC280_SIGMA
UPCMLD-DP138
UPCMLD-DP138:001
Xolegel
cis-1-Acetyl-4-(4-((2-(2,4-dichlorophenyl)-2-(1H- imidazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-ketoconazol
cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine
dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-piperazine
ketoconazole
12
PetrolatumPhase 0868009-03-8
Synonyms:
Multi-hydrocarbon
Paraffinum album
Paraffinum flavum
Petrolatum base
Petrolatum, white
 
Petrolatum,amber
Petrolatum,white
Petroleum jelly
Soft paraffin
White petrolatum
White, soft paraffin
Yellow soft paraffin

Interventional clinical trials:

(show all 27)
idNameStatusNCT IDPhase
1Intravitreal Bevacizumab in Recalcitrant Inflammatory Ocular NeovascularizationCompletedNCT00645697Phase 4
2A Study of the Efficacy and Safety of Voriconazole for the Treatment of Fungal InfectionsCompletedNCT00647907Phase 4
3A Randomized, Open, Comparative Multicenter Study of Initial Treatment With Intravenous Itraconazole Versus Amphotericin B Followed by Consolidation Treatment With Itraconazole Capsules in Patients With Blastomycosis or HistoplasmosisCompletedNCT00002159Phase 3
4Submacular Surgery Trials (SST)CompletedNCT00000150Phase 3
5A Pharmacokinetic Study of JK1211(Itraconazole [Itrizole]) Oral Solution in Participants With Deep Mycosis and Those With Febrile Neutropenia Suspected of Fungal InfectionCompletedNCT00784368Phase 3
6A Multi-center Study of Spherule-Derived CoccidioidinCompletedNCT00690092Phase 3
7Effect of Intravitreal Bevacizumab on Non -Age-Related Macular Degeneration (AMD) Related Choroidal Neovascularization (CNV)CompletedNCT00370786Phase 3
8Randomized Comparative Study of Fluconazole Versus Clotrimazole Troches in the Prevention of Serious Fungal Infection in Patients With AIDS or Advanced AIDS-Related Complex. (A Nested Study of ACTG 081)CompletedNCT00000676Phase 3
9Macular Photocoagulation Study (MPS)Active, not recruitingNCT00000158Phase 3
10A Study of Itraconazole in the Treatment and Prevention of Histoplasmosis, a Fungal Infection, in Patients With AIDSCompletedNCT00000975Phase 2
11Phase II Pilot Study of Fluconazole for Histoplasmosis, Blastomycosis, and SporotrichosisCompletedNCT00004808Phase 2
12Phase I/II Study of Itraconazole for Blastomycosis, Histoplasmosis, and SporotrichosisCompletedNCT00004811Phase 1, Phase 2
13Treatment for Presumed Ocular HistoplasmosisRecruitingNCT01790893Phase 1, Phase 2
14Ranibizumab Versus PDT for Presumed Ocular HistoplasmosisRecruitingNCT00546936Phase 2
15Intravitreal Ranibizumab for the Treatment of Choroidal Neovascularization in Ocular Histoplasmosis SyndromeRecruitingNCT00955630Phase 1, Phase 2
16A Study of Itraconazole in Preventing the Return of Histoplasmosis, a Fungal Infection, in Patients With AIDSCompletedNCT00000992Phase 1
17A Clinical Study to Evaluate the Pharmacokinetics of Lozanoc and Sporanox in Korean Healthy Male VolunteersCompletedNCT02493738Phase 1
18Intravitreal Aflibercept Injection (IAI) for Presumed Ocular Histoplasmosis SyndromeActive, not recruitingNCT01578720Phase 1
19Withdrawal of Antifungal Treatment for Histoplasmosis in Patients After Improved Immune Response to Anti-HIV DrugsCompletedNCT00006316
20Pilot Study to Determine the Feasibility of Fluconazole for Induction Treatment and Suppression of Relapse of Histoplasmosis in Patients With the Acquired Immunodeficiency SyndromeCompletedNCT00000627
21A Study of Itraconazole in the Prevention of Histoplasmosis, a Fungal Infection, in HIV-Infected PatientsCompletedNCT00002438
22A Comparison of HIV-Infected Patients With and Without Opportunistic (AIDS-Related) InfectionCompletedNCT00005572
23Topical Itraconazole in the Treatment of Basal Cell CarcinomaRecruitingNCT02120677Phase 0
24Prevalence of Histoplasmosis in HIV + Patients With a Rapid Diagnostic Test in West IndiesActive, not recruitingNCT01884779
25Additive Benefit of the Urine LAM Test to Current TB Diagnostics in HIV Positive Adults in Panama City, PanamaNot yet recruitingNCT02911740
26Macugen for HistoplasmosisTerminatedNCT00272766
27Intravitreal Bevacizumab vs.Combination Therapy for CNV Due to Other Than AMDWithdrawnNCT01256580

Search NIH Clinical Center for Histoplasmosis

Inferred drug relations via UMLS66/NDF-RT44:


Cochrane evidence based reviews: histoplasmosis

Genetic Tests for Histoplasmosis

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Anatomical Context for Histoplasmosis

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MalaCards organs/tissues related to Histoplasmosis:

34
Lung, Testes, Colon, Skin, Bone, Bone marrow, Kidney

Animal Models for Histoplasmosis or affiliated genes

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Publications for Histoplasmosis

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Articles related to Histoplasmosis:

(show top 50)    (show all 735)
idTitleAuthorsYear
1
Vertical Transmission of Histoplasmosis Associated With Anti-Tumor Necrosis Factor Therapy. (27012275)
2016
2
Spatial distribution of disseminated histoplasmosis and AIDS co-infection in an endemic area of Northeastern Brazil. (27192593)
2016
3
Childhood histoplasmosis in Colombia: Clinical and laboratory observations of 45 patients. (27118801)
2016
4
Sarcoidosis and Histoplasmosis: Is One a Consequence of the Other? A Case Report and Review of the Literature. (26345350)
2015
5
Bilateral adrenal histoplasmosis in a man with chronic alcoholism. (25908247)
2015
6
Histoplasmosis Complicating Tumor Necrosis Factor-I+ Blocker Therapy: A Retrospective Analysis of 98 Cases. (25870331)
2015
7
Histoplasmosis: Up-to-Date Evidence-Based Approach to Diagnosis and Management. (26398539)
2015
8
Histoplasmosis in a state where it is not known to be endemic-montana, 2012-2013. (24354878)
2014
9
Chronic ulceration of tongue. Histoplasmosis. (25115015)
2014
10
Application of nested PCR for diagnosis of histoplasmosis. (23345048)
2013
11
Progressive disseminated histoplasmosis presenting with cachexia and hypercalcemia. (23467543)
2013
12
Disseminated histoplasmosis in an apparently immunocompetent individual from north India: a case report and review. (23547881)
2013
13
Unusual presentations of disseminated histoplasmosis. (22715652)
2012
14
Disseminated cutaneous histoplasmosis in an immunocompetent adult. (22707773)
2012
15
Feline histoplasmosis: a retrospective study of 22 cases (1986-2009). (22474046)
2012
16
Serum Aspergillus galactomannan for the management of disseminated histoplasmosis in AIDS. (22855762)
2012
17
Histoplasmosis-induced pancytopenia. (23230591)
2012
18
Immunization with apoptotic phagocytes containing Histoplasma capsulatum activates functional CD8(+) T cells to protect against histoplasmosis. (21911464)
2011
19
Bilateral adrenal histoplasmosis: endoscopic ultrasound-guided fine needle aspiration as a method of diagnosis and assessment. (22390113)
2011
20
Renal allograft recipient with co-existing BK virus nephropathy and pulmonary histoplasmosis: report of a case. (20714773)
2010
21
Imported histoplasmosis: two distinct profiles in travelers and immigrants. (19674266)
2009
22
Disseminated histoplasmosis presenting as granulomatous epididymo-orchitis. (19745612)
2009
23
Disseminated histoplasmosis by Histoplasma capsulatum var. duboisii in a paediatric patient from the Chad Republic, Africa. (19005708)
2009
24
Case report: Esophageal histoplasmosis associated with disseminated tuberculosis in acquired immunodeficiency syndrome. (19270280)
2009
25
Histoplasmosis in children. (19879506)
2009
26
Oral histoplasmosis: an unusual presentation. (18798316)
2009
27
Disseminated histoplasmosis diagnosed on bone marrow aspirate cytology: report of four cases. (21591519)
2009
28
Mucocutaneous histoplasmosis in HIV with an atypical ecthyma like presentation. (19450403)
2009
29
Education and imaging. Gastrointestinal: Gastrointestinal histoplasmosis. (18397490)
2008
30
Outbreak of histoplasmosis among travelers returning from El Salvador--Pennsylvania and Virginia, 2008. (19092757)
2008
31
Images in emergency medicine. Erythema nodosum associated with pulmonary histoplasmosis. (19027494)
2008
32
Successful treatment of histoplasmosis brain abscess with voriconazole. (18474746)
2008
33
Disseminated histoplasmosis and tuberculosis in a patient with HIV infection. (17594164)
2007
34
Platelia Aspergillus assay for diagnosis of disseminated histoplasmosis. (17874253)
2007
35
Histoplasmosis-associated cross-reactivity in the BioRad Platelia Aspergillus enzyme immunoassay. (17344352)
2007
36
Molecular epidemiology of canine histoplasmosis in Japan. (17464845)
2007
37
Articular presentation of disseminated histoplasmosis. (16724167)
2007
38
Gastric histoplasmosis. (16377536)
2006
39
Preventing reactivation of ocular histoplasmosis: guidance for patients at risk. (16458241)
2006
40
Histoplasmosis in two aboriginal patients from Australia's tropical Northern Territory. (16483624)
2006
41
Maxillary African histoplasmosis: unusual diagnostic problems of an unusual presentation. (15792130)
2005
42
Histoplasmosis-like choroiditis in a nonendemic area: the northwest United States. (9654410)
1998
43
African histoplasmosis: osteomyelitis of the radius. (9670760)
1998
44
African histoplasmosis: a review. (15538817)
1997
45
Focal lesion of African histoplasmosis presenting as a malignant gastric ulcer. (8799429)
1996
46
Mandibular African histoplasmosis: imitation of neoplasia or giant-cell granuloma? (3422400)
1988
47
Multifocal choroiditis and panuveitis. A syndrome that mimics ocular histoplasmosis. (6508619)
1984
48
African histoplasmosis presenting as a dental problem. (5272571)
1970
49
Pathology of African histoplasmosis (H. duboisii)--light and electron microscopy. (4926980)
1970
50
Tinea capitis and African histoplasmosis in the Belgian Congo. (13443007)
1957

Variations for Histoplasmosis

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Expression for genes affiliated with Histoplasmosis

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Search GEO for disease gene expression data for Histoplasmosis.

Pathways for genes affiliated with Histoplasmosis

About this section

Pathways related to Histoplasmosis according to GeneCards Suite gene sharing:

(show all 23)
idSuper pathwaysScoreTop Affiliating Genes
19.9HLA-A, HLA-B
29.8HLA-DRB1, IFNG
39.8HLA-DRB1, IFNG
4
Show member pathways
9.6HLA-A, HLA-B, IFNG
59.5HLA-A, HLA-B, MICA
6
Show member pathways
9.5HLA-A, HLA-DRB1, IFNG
79.4HLA-DQA1, HLA-DRB1, IFNG
89.4C3, HLA-A, HLA-B
9
Show member pathways
9.2HLA-A, HLA-B, IFNG, MICA
109.2C3, HLA-DQA1, HLA-DRB1
119.1HLA-A, HLA-B, HLA-DQA1, HLA-DRB1
129.1HLA-A, HLA-B, HLA-DQA1, HLA-DRB1
139.1EGF, IFNG, TF
149.0C3, HLA-A, HLA-B, MICA
158.9C3, HLA-DQA1, HLA-DRB1, IFNG
16
Show member pathways
8.9C3, HLA-DQA1, HLA-DRB1, IFNG
178.9EGF, HLA-DQA1, HLA-DRB1
188.8HLA-A, HLA-B, HLA-DQA1, HLA-DRB1, IFNG
19
Show member pathways
8.8HLA-A, HLA-B, HLA-DQA1, HLA-DRB1, IFNG
208.6C3, HLA-A, HLA-B, HLA-DQA1, HLA-DRB1
21
Show member pathways
8.5HLA-A, HLA-B, HLA-DQA1, HLA-DRB1, IFNG, MICA
22
Show member pathways
8.3C3, HLA-A, HLA-B, HLA-DQA1, HLA-DRB1, IFNG
23
Show member pathways
7.1C3, EGF, HLA-A, HLA-B, HLA-DQA1, HLA-DRB1

GO Terms for genes affiliated with Histoplasmosis

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Cellular components related to Histoplasmosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1MHC class I protein complexGO:004261210.5HLA-A, HLA-B
2MHC class II protein complexGO:004261310.3HLA-DQA1, HLA-DRB1
3transport vesicle membraneGO:003065810.2HLA-DQA1, HLA-DRB1
4integral component of lumenal side of endoplasmic reticulum membraneGO:00715569.7HLA-A, HLA-B, HLA-DQA1, HLA-DRB1
5ER to Golgi transport vesicle membraneGO:00125079.7HLA-A, HLA-B, HLA-DQA1, HLA-DRB1
6Golgi membraneGO:00001399.3HLA-A, HLA-B, HLA-DQA1, HLA-DRB1
7cell surfaceGO:00099868.7HLA-A, HLA-B, HLA-DRB1, MICA, TF
8lysosomal membraneGO:00057658.3EGF, HLA-DQA1, HLA-DRB1, SLC17A5

Biological processes related to Histoplasmosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independentGO:000248010.4HLA-A, HLA-B
2antigen processing and presentation of peptide antigen via MHC class IGO:000247410.4HLA-A, HLA-B
3T cell receptor signaling pathwayGO:00508529.4HLA-DQA1, HLA-DRB1, IFNG
4interferon-gamma-mediated signaling pathwayGO:00603339.2HLA-A, HLA-B, HLA-DQA1, HLA-DRB1, IFNG
5antigen processing and presentationGO:00198829.1HLA-A, HLA-B, IFNG, MICA
6regulation of immune responseGO:00507768.4C3, HLA-A, HLA-B, IFNG, MICA

Molecular functions related to Histoplasmosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1beta-2-microglobulin bindingGO:00308819.7HLA-A, MICA
2peptide antigen bindingGO:00426059.1HLA-A, HLA-B, HLA-DQA1, HLA-DRB1

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
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29ICD10 via Orphanet
30ICD9CM
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32KEGG
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38MESH via Orphanet
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65Tumor Gene Family of Databases
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67UMLS via Orphanet