MCID: HVD003
MIFTS: 27

Hiv/aids malady

Summaries for Hiv/aids

Sources:
34MedlinePlus, 3CDC, 47OMIM, 33MalaCards
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MedlinePlus:34 Hiv stands for human immunodeficiency virus. it kills or damages the body's immune system cells. aids stands for acquired immunodeficiency syndrome. it is the most advanced stage of infection with hiv. hiv most often spreads through unprotected sex with an infected person. it may also spread by sharing drug needles or through contact with the blood of an infected person. women can give it to their babies during pregnancy or childbirth. the first signs of hiv infection may be swollen glands and flu-like symptoms. these may come and go a month or two after infection. severe symptoms may not appear until months or years later. a blood test can tell if you have hiv infection. your health care provider can perform the test, or call the national referral hotline at 1-800-cdc-info (24 hours a day, 1-800-232-4636 in english and en español; 1-888-232-6348 - tty). there is no cure, but there are many medicines to fight both hiv infection and the infections and cancers that come with it. people can live with the disease for many years.

MalaCards: Hiv/aids, also known as hiv-infection, is related to tuberculosis and hepatitis c. An important gene associated with Hiv/aids is CCL3L1 (chemokine (C-C motif) ligand 3-like 1), and among its related pathways are Salmonella infection and Chemokine Signaling.

CDC:3 Daily News HIV-related news stories compiled from media sources from across the US and other countries.

Description from OMIM:47 609423

Aliases & Classifications for Hiv/aids

Sources:
47OMIM, 34MedlinePlus, 61UMLS
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Aliases & Descriptions:

hiv/aids 47 34
hiv-infection 61


Related Diseases for Hiv/aids

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Hiv/aids:



Diseases related to hiv/aids

Clinical Features for Hiv/aids

Sources:
47OMIM
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Clinical features from OMIM:

609423

Drugs & Therapeutics for Hiv/aids

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Hiv/aids

Drug clinical trials:

Search ClinicalTrials for Hiv/aids

Search NIH Clinical Center for Hiv/aids

Search CenterWatch for Hiv/aids

Genetic Tests for Hiv/aids

Anatomical Context for Hiv/aids

Animal Models for Hiv/aids or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Hiv/aids

Genetic Variations for Hiv/aids

Expression for genes affiliated with Hiv/aids

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hiv/aids

Search GEO for disease gene expression data for Hiv/aids.

Pathways for genes affiliated with Hiv/aids

Sources:
30KEGG, 52QIAGEN, 53R&D Systems, 54Reactome, 12EMD Millipore, 38NCBI BioSystems Database
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Pathways related to Hiv/aids according to GeneCards/GeneDecks:

(show all 29)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.4CCL4L2, CCL3L1, CCL4L1
2
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10.3CCL4L2, CCR2, CCL3L1, CCL4L1, CCL27
3
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10.3CCL27, CCL4L1, CCL3L1, CCR2, CCL4L2
4
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10.3CCL4L2, CCR2, CCL3L1, CCL4L1, CCL27, NOX1
5
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10.3CCL4L2, CCR2, CCL3L1, CCL4L1, CCL27, NOX1
6
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10.1IFNA10, IFNA14, IFNA17, IFNA21, IFNA4, IFNA8
710.1IFNA4, IFNA8, IFNA5, IFNA7, IFNA6, IFNA21
8
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10.1IFNA16, IFNA10, IFNA14, IFNA17, IFNA21, IFNA4
910.1IFNA16, IFNA10, IFNA14, IFNA17, IFNA21, IFNA4
10
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10.1IFNA17, IFNA14, IFNA10, IFNA16, IFNA21, IFNA4
11
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10.1IFNA14, IFNA10, IFNA16, CCR2, IFNA17, IFNA21
1210.1IFNA16, IFNA10, IFNA14, IFNA17, IFNA21, IFNA4
1310.1IFNA16, IFNA10, IFNA14, IFNA17, IFNA21, IFNA4
1410.1IFNA8, IFNA5, IFNA13, IFNA7, IFNA6, IFNA4
15
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10.1IFNA16, IFNA10, IFNA14, IFNA17, IFNA21, IFNA4
1610.1IFNA14, IFNA17, IFNA21, IFNA4, IFNA8, IFNA5
17
Immune response TLR3 and TLR4 induce TICAM1-specific signaling pathway
10.1IFNA16, IFNA10, IFNA14, IFNA17, IFNA21, IFNA4
1810.1IFNA8, IFNA5, IFNA13, IFNA7, IFNA6, IFNA4
1910.1IFNA16, IFNA10, IFNA14, IFNA17, IFNA21, IFNA4
20
Hide members
10.1IFNA16, IFNA10, IFNA14, IFNA17, IFNA21, IFNA4
21
Immune response IFN alpha/beta signaling pathway
Hide members
10.1IFNA16, IFNA10, IFNA14, IFNA17, IFNA21, IFNA4
22
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10.1IFNA16, IFNA10, IFNA14, IFNA17, IFNA21, IFNA4
2310.1IFNA6, IFNA7, IFNA13, IFNA16, IFNA10, IFNA14
24
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10.1IFNA6, IFNA7, IFNA13, IFNA16, IFNA10, IFNA14
2510.1IFNA6, IFNA7, IFNA13, IFNA16, IFNA10, IFNA14
2610.0IFNA16, IFNA10, IFNA14, IFNA17, IFNA21, IFNA4
27
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10.0IFNA14, IFNA17, IFNA21, IFNA4, IFNA8, IFNA5
28
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10.0CCL4L2, CCL3L1, CCL4L1, IFNA16, IFNA10, IFNA14
29
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9.9CCL27, IFNA16, IFNA10, IFNA14, IFNA17, IFNA21

Compounds for genes affiliated with Hiv/aids

GO Terms for genes affiliated with Hiv/aids

Sources:
16Gene Ontology
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Cellular components related to Hiv/aids according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055769.9LCN1, IFNA7, IFNA13, IFNA5, IFNA8, IFNA4
2extracellular spaceGO:0056159.7CCL4L1, IFNA7, IFNA13, IFNA5, IFNA8, IFNA4

Biological processes related to Hiv/aids according to GeneCards/GeneDecks:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1chemotaxisGO:00693510.4CCR2, CCL4L1, CCL27
2regulation of type I interferon-mediated signaling pathwayGO:06033810.2IFNA16, IFNA10, IFNA14, IFNA17, IFNA21, IFNA4
3type I interferon-mediated signaling pathwayGO:06033710.2IFNA6, IFNA7, IFNA13, IFNA16, IFNA10, IFNA14
4defense response to virusGO:05160710.1IFNA16, IFNA10, IFNA14, IFNA17, IFNA21, IFNA4
5innate immune responseGO:04508710.0CCR2, IFNA16, IFNA10, IFNA14, IFNA17, IFNA21
6cytokine-mediated signaling pathwayGO:01922110.0IFNA21, IFNA4, IFNA8, IFNA5, IFNA13, IFNA7
7response to virusGO:00961510.0IFNA4, IFNA7, IFNA6, BST2, IFNA17
8blood coagulationGO:00759610.0IFNA4, IFNA8, IFNA5, IFNA13, IFNA7, IFNA6

Molecular functions related to Hiv/aids according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1interferon-alpha/beta receptor bindingGO:00513210.3IFNA7, IFNA13, IFNA4, IFNA17, IFNA16
2cytokine activityGO:00512510.0IFNA6, IFNA16, IFNA10, IFNA14, IFNA17, IFNA21
3cytokine receptor bindingGO:0051269.9IFNA10, IFNA14, IFNA21, IFNA8, IFNA5, IFNA6

Products for genes affiliated with Hiv/aids

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Hiv/aids

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet