MCID: HVD003
MIFTS: 40

Hiv/aids malady

Summaries for Hiv/aids

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35MedlinePlus, 4CDC, 48OMIM, 34MalaCards
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MedlinePlus:35 Hiv stands for human immunodeficiency virus. it kills or damages the body's immune system cells. aids stands for acquired immunodeficiency syndrome. it is the most advanced stage of infection with hiv. hiv most often spreads through unprotected sex with an infected person. it may also spread by sharing drug needles or through contact with the blood of an infected person. women can give it to their babies during pregnancy or childbirth. the first signs of hiv infection may be swollen glands and flu-like symptoms. these may come and go a month or two after infection. severe symptoms may not appear until months or years later. a blood test can tell if you have hiv infection. your health care provider can perform the test, or call the national referral hotline at 1-800-cdc-info (24 hours a day, 1-800-232-4636 in english and en espaƱol; 1-888-232-6348 - tty). there is no cure, but there are many medicines to fight both hiv infection and the infections and cancers that come with it. people can live with the disease for many years.

MalaCards: Hiv/aids, also known as hiv-infection, is related to acquired immunodeficiency syndrome and tuberculosis. An important gene associated with Hiv/aids is CCL3L1 (chemokine (C-C motif) ligand 3-like 1), and among its related pathways are Chemokine Superfamily: Human/Mouse Ligand-Receptor Interactions and Factors involved in megakaryocyte development and platelet production. The compound halothane have been mentioned in the context of this disorder. Affiliated tissues include testes, t cells and skin.

CDC:4 What's New in HIV e-HAP keeps you informed about the latest releases from CDC on HIV and related topics.

Description from OMIM:48 609423

Aliases & Classifications for Hiv/aids

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Sources:
48OMIM, 35MedlinePlus, 63UMLS
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Aliases & Descriptions:

hiv/aids 48 35
hiv-infection 63


Related Diseases for Hiv/aids

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Sources:
18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Hiv/aids:



Diseases related to hiv/aids

Symptoms for Hiv/aids

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48OMIM
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Clinical features from OMIM:

609423

Drugs & Therapeutics for Hiv/aids

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Hiv/aids

Drug clinical trials:

Search ClinicalTrials for Hiv/aids

Search NIH Clinical Center for Hiv/aids

Search CenterWatch for Hiv/aids

Genetic Tests for Hiv/aids

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Anatomical Context for Hiv/aids

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34MalaCards
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MalaCards organs/tissues related to Hiv/aids:

34
Testes, T cells, Skin, Brain, Kidney, Salivary gland, B cells, Thyroid, Colon, Smooth muscle, Heart, Whole blood, Eye, Dorsal root ganglion

Animal Models for Hiv/aids or affiliated genes

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Publications for Hiv/aids

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53PubMed
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Articles related to Hiv/aids:

(show top 50)    (show all 625)
idTitleAuthorsYear
1
Malignancies in HIV/AIDS: from epidemiology to therapeutic challenges. (24401642)
2014
2
Media use and HIV/AIDS knowledge: a knowledge gap perspective. (23644165)
2013
3
Welfare Homes for Patients with HIV/AIDS in Andalusia. (24162615)
2013
4
Oil, migration, and the political economy of HIV/AIDS prevention in Nigeria's Niger Delta. (24397234)
2013
5
Home-based caregiving for people living with HIV/AIDS in South Africa. (23728037)
2013
6
Oral health status of people living with HIV/AIDS attending a specialized service in Brazil. (24266613)
2013
7
The struggle for recognition by people living with HIV/AIDS in Sudan. (23515299)
2013
8
HIV/AIDS-related attitudes and oral impacts on daily performances: a cross-sectional study of Sudanese adult dental patients. (23971974)
2013
9
Providing HIV pre-exposure prophylaxis: lessons learned from the Ryan White HIV/AIDS Program. (23253757)
2013
10
Cutaneous candidiasis caused by Candida glabrata in a HIV/AIDS patient. (23970580)
2013
11
Patient preferences for HIV/AIDS therapy - a discrete choice experiment. (23663390)
2013
12
First Evidence of Genetic Intraspecific Variability and Occurrence of Entamoeba gingivalis in HIV(+)/AIDS. (24376598)
2013
13
Costs of providing food assistance to HIV/AIDS patients in Sofala province, Mozambique: a retrospective analysis. (24103560)
2013
14
Knowledge and Attitude of Basic Health Workers (BHWs) toward HIV/AIDS. (24362608)
2013
15
Assessment of HIV/AIDS knowledge, attitudes and behaviours among students in higher education in Tanzania. (24088049)
2013
16
Potential gains in life expectancy from reducing heart disease, cancer, Alzheimer's disease, kidney disease or HIV/AIDS as major causes of death in the USA. (23507421)
2013
17
Assessing the effects of drug misuse on HIV/AIDS prevalence. (23225069)
2013
18
Gender Differences in Health Related Quality of Life of People Living with HIV/AIDS in the Era of Highly Active Antiretroviral Therapy. (23641370)
2013
19
Impact of pharmacy technician-centered medication reconciliation on optimization of antiretroviral therapy and opportunistic infection prophylaxis in hospitalized patients with HIV/AIDS. (23340912)
2013
20
Trichomonas vaginalis and associated factors among women living with HIV/AIDS in Amazonas, Brazil. (23916452)
2013
21
Assessing the challenges of multi-scope clinical research sites: an example from NIH HIV/AIDS clinical trials networks. (24219425)
2013
22
Optimal diagnostic measures and thresholds for hypogonadism in men with HIV/AIDS: comparison between 2 transdermal testosterone replacement therapy gels. (23816769)
2013
23
Post-Kala-Azar Dermal Leishmaniasis: A Paradigm of Paradoxical Immune Reconstitution Syndrome in Non-HIV/AIDS Patients. (23634148)
2013
24
Factors affecting the HIV/AIDS epidemic: an ecological analysis of global data. (24235928)
2013
25
An ethnographic study of HIV/AIDS among Ayoreo sex workers: cultural factors and risk perception. (24028831)
2013
26
Trends in adolescent sexual behavior, impact of information, and attitudes about HIV/AIDS in Portugal. (24128038)
2013
27
Using a Mandatory Reporting Database to Recruit Persons Living With HIV/AIDS to Study Access to Care in Mississippi. (23945607)
2013
28
Culturally relevant HIV/AIDS education, prevention, screening and treatment for Canadian Inuit. (23618216)
2013
29
Health-related quality of life and physical functioning in people living with HIV/AIDS: a case-control design. (23802924)
2013
30
Gene therapy strategies for HIV/AIDS: preclinical modeling in humanized mice. (24351796)
2013
31
Developing an adherence support intervention for patients on antiretroviral therapy in the context of the recent IDU-driven HIV/AIDS epidemic in Estonia. (23391132)
2013
32
Effect of HIV infection on pregnancy-related mortality in sub-Saharan Africa: secondary analyses of pooled community-based data from the network for Analysing Longitudinal Population-based HIV/AIDS data on Africa (ALPHA). (23683643)
2013
33
Psychosocial Issues of Children Infected with HIV/AIDS. (23833337)
2013
34
The experience of HIV diagnosis among Aboriginal people living with HIV/AIDS and depression. (23539094)
2013
35
Operations research in HIV/AIDS. (23879358)
2013
36
Eye exam with indirect ophthalmoscopy for diagnosis of disseminated tuberculosis in patients with HIV/AIDS. (23418196)
2013
37
Substance Abuse Treatment, HIV/AIDS, and the Continuum of Response for People Who Inject Drugs. (23243517)
2012
38
Brain computed tomography of patients with HIV/AIDS before the advent of subsidized treatment program in Nigeria. (23661884)
2012
39
Successful testing and treating of HIV/AIDS in Indonesia depends on the addiction treatment modality. (23293529)
2012
40
Childbearing Decision Making: A Qualitative Study of Women Living with HIV/AIDS in Southwest Nigeria. (23320152)
2012
41
Prevalence of bacterial vaginosis and its risk factors in HIV/AIDS patients with abnormal vaginal discharge. (21771443)
2011
42
A complicated case of cholecystitis, listeriosis and HIV/AIDS. (22715268)
2011
43
HIV-associated nemaline rod myopathy: role of intravenous immunoglobulin therapy in two persons with HIV/AIDS. (18330038)
2008
44
Images in HIV/AIDS. HIV-associated lymphogranuloma venereum proctitis. (17396331)
2007
45
Images in HIV/AIDS. Invasive aspergillosis presenting as a neck mass in a person with HIV/AIDS. (17672013)
2007
46
Interaction between allelic variation in IL12B and CCR5 affects the development of AIDS: IL12B/CCR5 interaction and HIV/AIDS. (17148969)
2007
47
Activation and coreceptor expression of T lymphocytes induced by highly active antiretroviral therapy in Chinese HIV/AIDS patients. (17199940)
2006
48
Activation and coreceptor expression of T lymphocytes in HIV/AIDS patients of China. (15742159)
2005
49
The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity. (12676886)
2003
50
Influence of HIV/AIDS infection on some biochemical indicators of the nutritional status]. (12152477)
2002

Variations for Hiv/aids

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Expression for genes affiliated with Hiv/aids

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hiv/aids

Search GEO for disease gene expression data for Hiv/aids.

Pathways for genes affiliated with Hiv/aids

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Sources:
51PathCards, 55R&D Systems, 56Reactome, 31KEGG, 39NCBI BioSystems Database, 54QIAGEN, 61Thomson Reuters
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Pathways related to Hiv/aids according to GeneCards/GeneDecks:

(show all 22)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.7CCL3L1, CCR2
28.4IFNA16, IFNA17, IFNA10, IFNA21
3
Show member pathways
8.4IFNA16, IFNA21, IFNA10, IFNA17
4
Show member pathways
8.4IFNA10, IFNA21, IFNA16, IFNA17
57.8IFNA17, IFNA10, IFNA21, IFNA13, IFNA16
6
Show member pathways
7.8IFNA21, IFNA10, IFNA17, IFNA16, IFNA13
77.8IFNA17, IFNA16, IFNA10, IFNA21, IFNA13
87.8IFNA16, IFNA17, IFNA10, IFNA21, IFNA13
9
Show member pathways
Type III interferon signaling39
7.8IFNA17, IFNA13, IFNA21, IFNA10, IFNA16
107.8IFNA16, IFNA21, IFNA13, IFNA10, IFNA17
11
Show member pathways
7.8IFNA21, IFNA13, IFNA16, IFNA10, IFNA17
127.8IFNA21, IFNA10, IFNA17, IFNA16, IFNA13
13
Show member pathways
7.8IFNA17, IFNA16, IFNA13, IFNA21, IFNA10
14
Show member pathways
7.8IFNA17, IFNA16, IFNA13, IFNA10, IFNA21
15
Show member pathways
Immune response CD16 signaling in NK cells61
7.8IFNA13, IFNA16, IFNA17, IFNA21, IFNA10
16
Show member pathways
7.8IFNA21, IFNA16, IFNA17, IFNA10, IFNA13
177.8IFNA10, IFNA16, IFNA13, IFNA17, IFNA21
18
Show member pathways
Immune response Role of TLRs 3 and 4 in cell antiviral response TICAM1 specific signaling pathways61
Immune response IL 1 signaling pathway61
7.8IFNA13, IFNA17, IFNA16, IFNA10, IFNA21
197.8IFNA13, IFNA16, IFNA17, IFNA10, IFNA21
20
Show member pathways
Toll-like receptor signaling pathway39
Regulation of toll-like receptor signaling pathway39
7.5IFNA13, IFNA21, IFNA10, IFNA17, IFNA16, CCL3L1
21
Show member pathways
7.5CCL3L1, IFNA21, IFNA10, IFNA13, IFNA16, IFNA17
22
Show member pathways
7.1IFNA17, CCL3L1, CCR2, IFNA16, IFNA13, IFNA21

Compounds for genes affiliated with Hiv/aids

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Sources:
46Novoseek, 52PharmGKB, 30IUPHAR, 12DrugBank
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Compounds related to Hiv/aids according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1halothane46 52 30 1212.5FTH1, CYP2B6

GO Terms for genes affiliated with Hiv/aids

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17Gene Ontology
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Cellular components related to Hiv/aids according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055767.8IFNA21, IFNA10, IFNA17, IFNA16, IFNA13
2extracellular spaceGO:0056157.5IFNA16, IFNA17, IFNA10, IFNA21, IFNA13

Biological processes related to Hiv/aids according to GeneCards/GeneDecks:

(show all 15)
idNameGO IDScoreTop Affiliating Genes
1natural killer cell activation involved in immune responseGO:0023238.1IFNA16, IFNA13, IFNA21, IFNA10, IFNA17
2regulation of MHC class I biosynthetic processGO:0453438.1IFNA13, IFNA21, IFNA10, IFNA17, IFNA16
3positive regulation of peptidyl-serine phosphorylation of STAT proteinGO:0331418.1IFNA13, IFNA21, IFNA10, IFNA17, IFNA16
4T cell activation involved in immune responseGO:0022868.0IFNA13, IFNA21, IFNA10, IFNA17, IFNA16
5regulation of type I interferon-mediated signaling pathwayGO:0603388.0IFNA16, IFNA17, IFNA10, IFNA21, IFNA13
6B cell proliferationGO:0421008.0IFNA13, IFNA21, IFNA10, IFNA17, IFNA16
7response to exogenous dsRNAGO:0433308.0IFNA16, IFNA17, IFNA10, IFNA21, IFNA13
8adaptive immune responseGO:0022508.0IFNA13, IFNA21, IFNA10, IFNA17, IFNA16
9humoral immune responseGO:0069597.9IFNA16, IFNA17, IFNA10, IFNA21, IFNA13
10B cell differentiationGO:0301837.9IFNA13, IFNA21, IFNA10, IFNA17, IFNA16
11type I interferon signaling pathwayGO:0603377.9IFNA13, IFNA21, IFNA10, IFNA17, IFNA16
12blood coagulationGO:0075967.8IFNA16, IFNA17, IFNA10, IFNA21, IFNA13
13defense response to virusGO:0516077.7IFNA13, IFNA21, IFNA10, IFNA17, IFNA16
14cytokine-mediated signaling pathwayGO:0192217.4CCR2, IFNA13, IFNA21, IFNA10, IFNA17, IFNA16
15innate immune responseGO:0450877.1CCR2, IFNA13, IFNA21, IFNA10, IFNA17, IFNA16

Molecular functions related to Hiv/aids according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1iron ion bindingGO:0055069.5FTH1, CYP2B6
2type I interferon receptor bindingGO:0051327.7IFNA16, IFNA17, IFNA10, IFNA21, IFNA13
3cytokine activityGO:0051257.5IFNA13, IFNA21, IFNA10, IFNA17, IFNA16

Products for genes affiliated with Hiv/aids

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Hiv/aids

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet