Aliases & Classifications for Homocysteinemia

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Aliases & Descriptions for Homocysteinemia:

Name: Homocysteinemia 46 48 66

Classifications:



Summaries for Homocysteinemia

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MalaCards based summary: Homocysteinemia is related to homocystinuria due to mthfr deficiency and artery disease. An important gene associated with Homocysteinemia is MTHFR (Methylenetetrahydrofolate Reductase), and among its related pathways are Folate Metabolism and Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE. Affiliated tissues include heart, endothelial and ovary, and related mouse phenotype homeostasis/metabolism.

Related Diseases for Homocysteinemia

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Diseases related to Homocysteinemia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 157)
idRelated DiseaseScoreTop Affiliating Genes
1homocystinuria due to mthfr deficiency32.9MTHFR, MTR
2artery disease29.9CRP, F2
3ischemic heart disease29.8CRP, F2
4myocardial infarction29.2CRP, F2, F5, MTHFR
5mental retardation, x-linked 311.4
6homocystinuria11.4
7congenital intrinsic factor deficiency10.7MTR, MTRR
8x-linked disease10.7MTR, MTRR
9serine deficiency10.6MTHFR, MTR
10dental abscess10.6CRP, MTHFR
11factor v leiden thrombophilia10.6MTR, MTRR
12michels caskey syndrome10.6F5, MTHFR
13congenital stenosis of the inferior vena cava10.6F5, MTHFR
14nutritional deficiency disease10.6CRP, MTHFR
15ameloblastic carcinoma10.6F5, MTHFR
16pregnancy loss, recurrent 110.6F5, MTHFR
17methylmalonic aciduria and homocystinuria type cblg10.6MTHFR, MTR
18islet cell tumor10.6CRP, MTHFR
19catatrichy10.6F5, MTHFR
20pneumocystosis10.6CRP, MTHFR
21urinary bladder cancer10.5F5, MTHFR
22acquired hypoprothrombinemia10.5CRP, F5
23mental retardation, autosomal recessive 3310.5CRP, MTHFR
24hepatoid pattern testicular yolk sac tumor10.5CRP, F5
25functional diarrhea10.5FBN1, MTHFR
26cervix erosion10.5CRP, MTHFR
27methylmalonic aciduria and homocystinuria, cblc type10.5MMACHC, MTR
28schizencephaly10.4F5, MTHFR
29neural tube defects, folate-sensitive10.4MTHFR, MTR, MTRR
30coloboma-obesity-hypogenitalism-mental retardation syndrome10.4MTHFR, MTR, MTRR
31rasa1-related disorders10.4F2, MTHFR
32typhoid fever10.4F2, MTHFR
33x-linked congenital generalized hypertrichosis10.4MTHFR, MTR, MTRR
34autosomal recessive type iv ehlers-danlos syndrome10.4MMACHC, MTR
35agammaglobulinemia 210.4MTHFR, MTR, MTRR
36ectopic pregnancy10.4MTHFR, MTR, MTRR
37hypertensive heart disease10.4F2, MTHFR
38lymphatic system cancer10.3F2, MTHFR
39chronic fungal otitis externa10.3CRP, F2
40histoplasmosis10.3F2, MTHFR
41elejalde disease10.3F2, MTHFR
42postmenopausal atrophic vaginitis10.3CRP, F2
43oral cavity carcinoma in situ10.3CRP, F2
44intracranial arteriosclerosis10.3F2, MTHFR
45lateral cystocele10.3CRP, F2
46classic congenital lipoid adrenal hyperplasia due to star deficency10.3F2, F5
47choroid necrotic melanoma10.3F5, MTHFR
48collagenous colitis10.3F2, F5
49bartholin's gland adenoma10.3F2, F5
50thrombophilia due to thrombin defect10.3F2, F5

Graphical network of the top 20 diseases related to Homocysteinemia:



Diseases related to homocysteinemia

Symptoms for Homocysteinemia

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Drugs & Therapeutics for Homocysteinemia

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Drugs for Homocysteinemia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
HydroxocobalaminPhase 323613422-51-011953898, 5460373, 44475014
Synonyms:
13422-51-0
22465-48-1
78091-12-0
8017-22-9
Acti-B12
AlphaRedisol
AlphaRedisol (TN)
Axion
Axlon
Benzimidazolyl ribofuranosyl phosphate deriv.
C08230
C62H85CoN13O15P
CHEBI:27786
CHEMBL1200742
CHEMBL235822
CID11622291
CID11953898
CID5460373
CID6433575
CID6474319
Ciplamin H
Coalpha-[alpha-(5,6-dimethylbenzimidazolyl)]-Cobeta-hydroxocobamide
Cobalex
Cobalin H
Cobinamide dihydroxide dihydrogen phosphate (ester), mono(inner salt), 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole
Cobinamide hydroxide phosphate 3'-ester with 5,6-dimethyl-1-a-D-ribofuranosylbenzimidazole inner salt
Cobinamide hydroxide phosphate 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole inner salt
Cobinamide hydroxide phosphate 3'-ester with 5,6-dimethyl-1-alpha-delta-ribofuranosylbenzimidazole inner salt
Cobinamide, Co-hydroxy-, dihydrogen phosphate (ester), inner salt, 3'-ester with (5,6-dimethyl-1-alpha-D-ribofuranosyl-1H-benzimidazole-kappaN3)
Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3'-ester with (5,6-dimethyl-1-alpha-D-ribofuranosyl-1H-benzimidazole-kappaN3)
Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono (inner salt), 3'- ester with 5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole
Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono(inner salt), 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosyl-1H-benzimidazole
Cobinamide, hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosyl-1H-benzimidazole
Codroxomin
Cyanokit
Cyanokit (TN)
D01027
DB00200
Depogamma
Docclan
Docelan
Docelvita
Docevita
Droxomin
Ducobee Hy
Ducobee-Hy
Duradoce
Duralta-12
EINECS 236-533-2
HSDB 3342
HYDROXOCOBALAMIN
Hidroxocobalamina
Hidroxocobalamina [INN-Spanish]
Hydro Cobex
 
Hydrobamine
Hydrocobalamin
Hydrogrisevit
Hydrovit
Hydroxocobalamin
Hydroxocobalamin (JAN/USP/INN)
Hydroxocobalamin Vitamin B12
Hydroxocobalamin [USAN:INN:BAN:JAN]
Hydroxocobalamin acetate
Hydroxocobalamin anhydrous
Hydroxocobalamin monohydrochloride
Hydroxocobalamin(alkaline soln.), OH- replaces CN- in Cyanocobalamin)
Hydroxocobalaminacetat
Hydroxocobalamine
Hydroxocobalamine [INN-French]
Hydroxocobalaminum
Hydroxocobalaminum [INN-Latin]
Hydroxocobalaminum anhydrous
Hydroxocobemine
Hydroxomin
Hydroxy Cobal
Hydroxy vitamin B12
Hydroxycob(lll)alamin
Hydroxycobalamin
Hydroxycobalamine
Hyxobamine
Idrogrisevit
Idrossocobalamina
Idrossocobalamina [DCIT]
LS-54607
Lyovit-H
Neo-Betalin 12
Neo-cytamen
Neo-macrabin
Neo-rojamin
OH-Cbl
OH-Duphar
Ohb12
Oxobemin
Oxolamine (arcum)
Primabalt RP
Redisol-H
S1668_Selleck
Sytobex-H
UNII-Q40X8H422O
Vibeden
Vitadurin
Vitamin B(sub 12a)
Vitamin B-12b
Vitamin B12a
Vitamin B12b
a-(5,6-Dimethylbenzimidazolyl)hydroxocobamide
alpha Cobione
alpha-(5,6-Dimethylbenzimidazolyl)hydroxocobamide
vitamin B-12b
2
PyridoxalNutraceuticalPhase 317966-72-81050
Synonyms:
2-methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine
3-Hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carboxaldehyde
3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde
 
3-hydroxy-5-(hydroxymethyl)-2-methylisonicotinaldehyde
3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carboxaldehyde
Piridoxal
Pyridoxal
Pyridoxaldehyde
3
PyridoxineNutraceuticalPhase 318065-23-61054
Synonyms:
(5-hydroxy-4,6-dimethylpyridin-3-yl)methyl phosphate
12001-78-4
2-Methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine
2-Methyl-3-hydroxy-4,5-di(hydroxymethyl)pyridine
2-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridin
2-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridin [German]
2-Methyl-3-hydroxy-4,5-dihydroxymethylpyridine
2-Methyl-4,5-bis(hydroxymethyl)-3-hydroxypyridine
2-methyl-3-hydroxy-4,5-bis(hydroxy-methyl) pyridine
2-methyl-3-hydroxy-4,5-dihydroxymethylpyridine
2-methyl-4,5-dimethylol-pyridin-3-ol
2B3E07D2-E4CC-4CC5-B085-6070BA01F9F0
3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-, hydrochloride
3-Hydroxy-2-Picoline-4,5-dimethanol
3-Hydroxy-4,5-dihydroxymethyl-2-methylpyridine hydrochloride
3-Hydroxy-4,5-dimethylol-.alpha.-picoline hydrochloride
3-Hydroxy-4,5-dimethylol-alpha-picoline
3-Hydroxy-4,5-dimethylol-alpha-picoline hydrochloride
3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine
4,5-Bis(hydroxymethyl)-2-methyl-3-pyridinol
4,5-Bis(hydroxymethyl)-2-methylpyridin-3-ol hydrochloride
4,5-bis(hydroxymethyl)-2-methyl-3-pyridinol hydrochloride
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol
4,5-bis(hydroxymethyl)-2-methylpyridine-3-ol
4-Deoxypyridoxine 5'-phosphate
47862_SUPELCO
5-Hydroxy-6-methyl-3,4-pyridinedicarbinol hydrochloride
5-Hydroxy-6-methyl-3,4-pyridinedimethanol
5-Hydroxy-6-methyl-3,4-pyridinedimethanol hydrochloride
5-Hydroxy-6-methyl-3,4-pyridinedimethanol, hydrochloride
58-56-0
58-56-0 (HCL)
58-56-0 (hydrochloride)
65-23-6
65-23-6 (Parent)
8059-24-3
85078-23-5
AC-12024
AC-14512
AC-907/25014218
AC1L1AMH
AC1L1LMI
AC1L2XK2
AC1Q22HP
AC1Q2G66
AC1Q3F63
AI3-19016
AIDS-006784
AIDS006784
AR-1A6363
AR-1J1632
Adermin hydrochloride
Adermine
Adermine hydrochloride
Aderomine hydrochloride
Aderoxin
Aderoxine
Alestrol
BB_NC-0050
BIDD:PXR0180
BPBio1_000646
BSPBio_000586
Becilan
Beesix
Benadon
Bonasanit
C00314
C8H11NO3
CAS-58-56-0
CBDivE_015627
CCRIS 1903
CHEBI:16709
CHEBI:30961
CHEMBL1200756
CHEMBL1364
CID104817
CID1054
CID6019
CPD0-1221
Campoviton 6
Cernevit-12
D02179
D025101
D08454
DB00165
EINECS 200-386-2
EINECS 200-603-0
EINECS 232-503-8
Godabion
Gravidox
HMS1569N08
HMS2093L07
HSDB 1212
Hexa-Betalin
Hexa-Betalin (R)
Hexa-betalin (TN)
Hexabetalin
Hexabione hydrochloride
 
Hexavibex
Hexermin
Hexermine
Hexobion
Hydoxin
I02-1897
I02-2297
KST-1A8556
LS-134393
LS-187072
LS-2332
MLS001074329
MLS002153915
MolPort-002-137-856
MolPort-002-319-991
MolPort-005-933-330
NCGC00016261-01
NCGC00164317-01
NCGC00180946-01
NSC 36225
NSC36225
NSC36225 (HCL)
Nestrex
Oprea1_061614
P0561
P4722_SIAL
P5669_SIGMA
P6280_SIGMA
P8666_SIGMA
P9755_SIAL
PN
PN HCl
PYRIDOXINE HYDROCHLORIDE
PYRIDOXINE HYDROCHLORIDE, U.S.P.
Paxadon
Piridossina
Piridossina [DCIT]
Piridoxina
Piridoxina [INN-Spanish]
Prestwick0_000623
Prestwick1_000623
Prestwick2_000623
Prestwick3_000623
Prestwick_925
Pydox
Pyridipca
Pyridox
Pyridoxin
Pyridoxin hydrochloride
Pyridoxine
Pyridoxine (INN)
Pyridoxine HCl
Pyridoxine Hydrochloride (B6)
Pyridoxine [INN:BAN]
Pyridoxine chloride
Pyridoxine hydrochloride (JP15/USP)
Pyridoxine hydrochloride [USAN:JAN]
Pyridoxine hydrogen chloride
Pyridoxine monohydrochloride
Pyridoxine, hydrochloride
Pyridoxine-HCl Microencapsulated
Pyridoxinium chloride
Pyridoxinum
Pyridoxinum [INN-Latin]
Pyridoxinum hydrochloricum
Pyridoxinum hydrochloricum (Hungarian)
Pyridoxol
Pyridoxol hydrochloride
Pyridoxol, hydrochloride
Pyridoxolum
Rodex
Rodex (R)
Rodex TD
SMP2_000230
SMR000674613
SPBio_002805
STK177324
STOCK1N-08684
Spondylonal
Tex Six T.R.
TimTec1_000657
UNII-68Y4CF58BV
UNII-KV2JZ1BI6Z
Vitamin B 6
Vitamin B6
Vitamin B6-hydrochloride
Vitamin V6
Vitamin V6 (TN)
Vitamin-?B6
Vitamin-?B6 hydrochloride
Vitaped
WLN: T6NJ B1 CQ D1Q E1Q &GH
ZINC00049154
ZINC21983293
bmse000288
c1302
component of Alestrol
nchembio.93-comp1
pyridoxine
vitamin B6
4Vitamin B12NutraceuticalPhase 3237
5
MethylcobalaminNutraceuticalPhase 323713422-55-4
Synonyms:
Algobaz
Co-Methylcobalamin
Co-methylcobalamin
Hitocobamin M
MeCbl
Mecobalamin
Methycobal
 
Methyl cobalamine
Methyl vitamin B12
Methyl-5,6-dimethylbenzimidazolylcobalamin
Methyl-B12
Methylcob(III)alamin
Methylcobalamin
Methylcobaz
mecobalamin
methyl(III)cobalamin
6
cobalaminNutraceuticalPhase 323713408-78-16438156
Synonyms:
5,6-Dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole
5,6-Dimethyl-1-a-D-ribofuranosylbenzimidazole
5,6-Dimethyl-1-alpha-delta-ribofuranosyl-1H-benzimidazole
5,6-Dimethyl-1-alpha-delta-ribofuranosylbenzimidazole
Cob(III)alamin
Cobalamin (III)
Cobalamine
 
Cobinamide ion(1+) dihydrogen phosphate (ester) inner salt 3'-ester
Cobinamide ion(1+) dihydrogen phosphate (ester) inner salt 3'-ester with 5,6-dimethyl-1-alpha-delta-ribofuranosyl-1H-benzimidazole
Hydroxomin
Rubivite
Rubratope-57
Rubratope-60
Ruvite
Vitamin B12
7FolateNutraceuticalPhase 34143
8
Folic AcidNutraceuticalPhase 3414359-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
9
CyanocobalaminNutraceuticalPhase 323768-19-944176380
Synonyms:
Anacobin
Bedoz
Berocca PN
Berubigen
Betalin 12
Betalin 12 Crystalline
Betaline-12
Betolvex
Bevidox
Bevidox concentrate
Biocobalamine
Byladoce
Cabadon m
Cernevit-12
Cobadoce forte
Cobalin
Cobavite
Cobex
Cobolin-M
Copharvit 5000
Covit
Crystamin
Crystamine
Crysti-12
Crystimin
Crystwel
Cyano-B12
Cyanobalamin concentrate
Cyanocob(III)alamin
Cyanocobalamin (JP15/USP)
Cyanocobalamin Co 57 Schilling Test Kit
Cyanocobalamine
Cyanocobalmin
Cyanoject
Cycobemin
Cycolamin
Cykobemin
Cykobeminet
Cyomin
Cyredin
Cytacon
Cytamen
Cytobion
Depinar
Dicopac
Dicopac Kit
Dimethylbenzimidazoylcobamide
Distivit
Docemine
Docibin
Docivit
Dodecabee
Dodecavite
Dodex
Duodecibin
Embiol
Emociclina
Eritrone
Erycytol
 
Erythrotin
Euhaemon
Extrinsic factor
Factor II
Fermin
Fresmin
Hemomin
Hepagon
Hepavis
Hepcovite
Hylugel plus
Infuvite Pediatric
Lactobacillus lactis dorner factor
M.V.I. Pediatric
Macrabin
Megabion
Megalovel
Milbedoce
Millevit
Nagravon
Nascobal
Nascobal (TN)
Neuroforte-R
Normocytin
Novidroxin
Pernaemon
Pernaevit
Pernipuron
Plecyamin
Poyamin
Primabalt
Rebramin
Redamina
Redisol
Rhodacryst
Rubesol
Rubivite
Rubramin
Rubramin PC
Rubratope-57 Kit
Rubratope-60 Kit
Rubripca
Rubrocitol
Ruvite
Shovite
Sytobex
Vi-Twel
Vibal
Vibalt
Vibisone
Virubra
Vita-rubra
Vitabee 12
Vitamin B12
Vitamin B12 Preparation
Vitamin B12 complex
Vitaped
Vitarubin
Vitral
vitamine b12

Interventional clinical trials:

idNameStatusNCT IDPhase
1Homocysteine Study (HOST)CompletedNCT00032435Phase 3
2Effect of Cerefolin®/CerefolinNAC® on Biomarker MeasurementsCompletedNCT01745198
3Study of Factors Influencing Post-stroke DementiaRecruitingNCT01330160

Search NIH Clinical Center for Homocysteinemia

Genetic Tests for Homocysteinemia

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Anatomical Context for Homocysteinemia

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MalaCards organs/tissues related to Homocysteinemia:

34
Heart, Endothelial, Ovary, Testes, Liver, Smooth muscle, Kidney

Animal Models for Homocysteinemia or affiliated genes

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MGI Mouse Phenotypes related to Homocysteinemia:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053766.2CLU, CRP, F2, F5, FBN1, MTHFR

Publications for Homocysteinemia

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Articles related to Homocysteinemia:

(show top 50)    (show all 115)
idTitleAuthorsYear
1
Homocysteinemia is Associated with a Lower Degree of PBMC LINE-1 Methylation and a Higher Risk of CIN 2C in the U.S. Post-Folic Acid Fortification Era. (27008272)
2016
2
Homocysteinemia due to MTHFR deficiency in a young adult presenting with bilateral lens subluxations. (27046515)
2016
3
Homocysteinemia and early outcome of acute ischemic stroke in elderly patients. (27096104)
2016
4
Clinical presentation, gene analysis and outcomes in young patients with early-treated combined methylmalonic acidemia and homocysteinemia (cblC type) in Shandong province, China. (26563984)
2015
5
Homocysteinemia After Hypertensive Pregnancy Disorders at Term. (26070038)
2015
6
Preventive effects of Lentinus edodes on homocysteinemia in mice. (24137209)
2013
7
Inflammatory status in chronic renal failure: The role of homocysteinemia and pro-inflammatory cytokines. (24175263)
2013
8
Increased homocysteinemia is associated with beneficial effects on body weight after long-term high-protein, low-fat diet in rats. (22554959)
2012
9
Study of the effect of antiviral therapy on homocysteinemia in hepatitis C virus- infected patients. (22925702)
2012
10
Triacylglycerol/phospholipid molecular species profiling of fatty livers and regenerated non-fatty livers in cystathionine beta-synthase-deficient mice, an animal model for homocysteinemia/homocystinuria. (21301820)
2011
11
Relation of homocysteinemia to contrast-induced nephropathy in patients undergoing percutaneous coronary intervention. (21791335)
2011
12
Homocysteinemia in polycystic ovary syndrome women]. (20512259)
2010
13
Severe In vivo hyper-homocysteinemia is not associatedwith elevation of amyloid-beta peptides in the Tg2576 mice. (20555139)
2010
14
Cysteinemia, rather than homocysteinemia, is associated with plasma apolipoprotein A-I levels in hyperhomocysteinemia: lipid metabolism in cystathionine beta-synthase deficiency. (20537649)
2010
15
The metabolic syndrome is not associated with homocysteinemia: the Persian Gulf Healthy Heart Study. (19794288)
2009
16
Homocysteinemia in hypertensive patients with renal target organ damage (mild renal dysfunction). (18559300)
2008
17
Differential associations between lipid-lowering drugs, statins and fibrates, and venous thromboembolism: role of drug induced homocysteinemia? (18048086)
2008
18
A possible new risk factor in diabetic patients with erectile dysfunction: homocysteinemia. (18413215)
2008
19
Homocysteinemia as an independent risk factor in the Chinese population at a high risk of coronary artery disease. (17659928)
2007
20
Association between homocysteinemia and metabolic syndrome in patients with cardiovascular disease. (18516267)
2007
21
Influence of PON1 polymorphisms on the association between serum paraoxonase 1 and homocysteinemia in a general population. (16595840)
2006
22
The cognitive impact of nutritional homocysteinemia in apolipoprotein-E deficient mice. (16917146)
2006
23
Homocysteinemia is a risk factor for aortic dissection. (15780501)
2005
24
The achievement of normal homocysteinemia in regular extracorporeal dialysis patients. (15365962)
2004
25
A case of ischemic cerebral infarction associated with acute posterior multifocal placoid pigment epitheliopathy, CNS vasculitis, vitamin B(12) deficiency and homocysteinemia. (15383766)
2004
26
Homocysteinemia in psychiatric disorders: association with dementia and depression, but not schizophrenia in female patients. (14666412)
2003
27
Homocysteinemia and ovariectomy--initial experience with functional monitoring]. (12661370)
2002
28
Association between homocysteinemia and renal function in patients with type 2 diabetes mellitus. (12175091)
2002
29
Homocysteinemia in the emergency department. (11014083)
2000
30
Homocysteinemia, serum folate and vitamin B12 in very young patients with diabetes mellitus type 1. (11154158)
2000
31
Pulmonary thrombosis, homocysteinemia, and reperfusion edema in an adolescent. (10816282)
2000
32
A polymorphism (80G->A) in the reduced folate carrier gene and its associations with folate status and homocysteinemia. (10993718)
2000
33
Differential diagnosis of chest pain in an emergency department: the value of homocysteinemia as a diagnostic marker. (11014082)
2000
34
Clinical spectrum and diagnosis of homocysteinemia. (11339437)
2000
35
Homocysteinemia and risk for cardiovascular disease. (11339436)
2000
36
Homocysteinemia and livedoid vasculitis. (10025764)
1999
37
Homocysteinemia: new information about an old risk factor for vascular disease. (10537928)
1998
38
Atherogenic diet alters folate enzymes in mice: implications of folate deficient homocysteinemia. (10410464)
1998
39
Homocysteinemia as a risk factor for atherosclerosis: a review. (9423939)
1997
40
Myocardial infarction in a 35-year-old man with homocysteinemia, high plasminogen activator inhibitor activity, and resistance to activated protein C. (9439545)
1997
41
Homocysteinemia and vascular disease in end-stage renal disease. (8941916)
1996
42
The pathogenesis of homocysteinemia: interruption of the coordinate regulation by S-adenosylmethionine of the remethylation and transsulfuration of homocysteine. (1728812)
1992
43
Homocysteinemia: a risk factor for vascular disease. (1881423)
1991
44
Intermediate homocysteinemia: a thermolabile variant of methylenetetrahydrofolate reductase. (3177384)
1988
45
Homocysteinemia: depressed plasma serine levels. (3100911)
1987
46
Folic acid responsive postmenopausal homocysteinemia. (3932819)
1985
47
Homocysteinemia, ischemic heart disease, and the carrier state for homocystinuria. (6684724)
1983
48
Homocysteine thiolactone and experimental homocysteinemia. (7082327)
1982
49
Experimental homocysteinemia in pigs: comparison with studies in sixteen homocystinuric patients. (7098848)
1982
50
Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis. (5792556)
1969

Variations for Homocysteinemia

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Expression for genes affiliated with Homocysteinemia

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Search GEO for disease gene expression data for Homocysteinemia.

Pathways for genes affiliated with Homocysteinemia

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Pathways related to Homocysteinemia according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.9MTHFR, MTRR
2
Show member pathways
9.8MTR, MTRR
3
Show member pathways
9.5MTHFR, MTR, MTRR
4
Show member pathways
9.4MMACHC, MTR, MTRR
59.4MMACHC, MTR, MTRR
69.2MMACHC, SLC19A1
7
Show member pathways
8.9CLU, F2, F5
8
Show member pathways
8.8CRP, F2, MTHFR, MTR
9
Show member pathways
8.2MMACHC, MTHFR, MTR, MTRR, SLC19A1

GO Terms for genes affiliated with Homocysteinemia

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Cellular components related to Homocysteinemia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:00056158.0CLU, CRP, F2, F5, FBN1

Biological processes related to Homocysteinemia according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1methionine metabolic processGO:000655510.4MTHFR, MTRR
2methionine biosynthetic processGO:000908610.3MTR, MTRR
3sulfur amino acid metabolic processGO:000009610.1MTR, MTRR
4acute-phase responseGO:00069539.6CRP, F2
5cobalamin metabolic processGO:00092359.5MMACHC, MTR, MTRR
6blood circulationGO:00080159.5F5, MTHFR
7folic acid metabolic processGO:00466559.0MTHFR, MTRR, SLC19A1

Molecular functions related to Homocysteinemia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1NADP bindingGO:00506619.9MTHFR, MTRR
2cobalamin bindingGO:00314199.7MMACHC, MTR

Sources for Homocysteinemia

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet