Aliases & Classifications for Hordeolum

MalaCards integrated aliases for Hordeolum:

Name: Hordeolum 12 41 14 69
Stye 12 72
Hordeolum Externum 69
Furuncle of Eyelid 12
Boil of Eyelid 12

Classifications:



External Ids:

Disease Ontology 12 DOID:9909
ICD10 32 H00.01
MeSH 41 D006726
NCIt 46 C118722
UMLS 69 C0019917

Summaries for Hordeolum

Disease Ontology : 12 Hordeolum is a sequelae of infectious and parasitic disease consisting of an infection of the sebaceous glands at the base of the eyelashes. Styes are generally caused by a Staphylococcus aureus bacterial infection.

MalaCards based summary : Hordeolum, also known as stye, is related to internal hordeolum and hordeolum externum. An important gene associated with Hordeolum is IFT122 (Intraflagellar Transport 122). The drugs Estradiol and Norgestimate have been mentioned in the context of this disorder. Affiliated tissues include eye.

Wikipedia : 72 A stye, also known as a hordeolum, is a bacterial infection of an oil gland in the eyelid. This results... more...

Related Diseases for Hordeolum

Diseases in the Hordeolum family:

Internal Hordeolum

Diseases related to Hordeolum via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 internal hordeolum 32.9 IFT122 PNP
2 hordeolum externum 12.1
3 meibomian cyst 10.0
4 bacteremia 2 9.9
5 orbital cellulitis 9.9
6 cellulitis 9.9
7 pyogenic granuloma 9.9

Graphical network of the top 20 diseases related to Hordeolum:



Diseases related to Hordeolum

Symptoms & Phenotypes for Hordeolum

Drugs & Therapeutics for Hordeolum

Drugs for Hordeolum (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 67)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Estradiol Approved, Investigational, Vet_approved Phase 4 50-28-2 5757
2
Norgestimate Approved, Investigational Phase 4 35189-28-7 6540478
3
Ofloxacin Approved Phase 4 82419-36-1 4583
4
Metronidazole Approved Phase 4 443-48-1 4173
5
Moxifloxacin Approved, Investigational Phase 4 151096-09-2, 354812-41-2 152946
6
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
7
Levofloxacin Approved, Investigational Phase 4 100986-85-4 149096
8
Tobramycin Approved, Investigational Phase 4 32986-56-4 36294 5496
9
Loteprednol Approved Phase 4 129260-79-3, 82034-46-6 9865442 444025
10 Estradiol valerate Phase 4 979-32-8
11 Renal Agents Phase 4
12 Fluoroquinolones Phase 4
13 Topoisomerase Inhibitors Phase 4
14 Contraceptive Agents Phase 4
15 Contraceptives, Oral Phase 4
16 Contraceptives, Oral, Combined Phase 4
17 Cytochrome P-450 CYP1A2 Inhibitors Phase 4
18 Cytochrome P-450 Enzyme Inhibitors Phase 4
19 Norgestimate, ethinyl estradiol drug combination Phase 4
20 Nucleic Acid Synthesis Inhibitors Phase 4
21 Anti-Bacterial Agents Phase 4,Phase 3
22 Estradiol 17 beta-cypionate Phase 4
23 Estradiol 3-benzoate Phase 4
24 Anti-Infective Agents Phase 4,Phase 3
25 Polyestradiol phosphate Phase 4
26 Antiprotozoal Agents Phase 4
27 Antiparasitic Agents Phase 4
28 Anti-Allergic Agents Phase 4
29
Neomycin Approved, Vet_approved Phase 3 1404-04-2 8378
30
Triamcinolone Approved, Vet_approved Phase 3 124-94-7 31307
31
Fluorouracil Approved Phase 3 51-21-8 3385
32 Polymyxin B Phase 3
33 Gramicidin Phase 3
34 Tetrahydrozoline Phase 3,Phase 1,Phase 2
35 Ophthalmic Solutions Phase 3,Phase 1,Phase 2
36 Pharmaceutical Solutions Phase 3,Phase 1,Phase 2
37 Polymyxins Phase 3
38 Anti-Infective Agents, Local Phase 3
39 Antibiotics, Antitubercular Phase 3
40 Lubricant Eye Drops Phase 3
41 Antitubercular Agents Phase 3
42 triamcinolone acetonide Phase 3
43 glucocorticoids Phase 3
44 Triamcinolone diacetate Phase 3
45 Triamcinolone hexacetonide Phase 3
46 Hormone Antagonists Phase 3
47 Hormones Phase 3
48 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3
49 Immunosuppressive Agents Phase 3
50 Antimetabolites Phase 3

Interventional clinical trials:

(show all 11)

# Name Status NCT ID Phase Drugs
1 Efficacy and Safety Trial to Assess Moxifloxacin in Treating Community-Acquired Pneumonia (CAP) With Aspiration Factors Unknown status NCT00752947 Phase 4 moxifloxacin;levofloxacin;metronidazole
2 Pediatric Zylet Safety and Efficacy Study Completed NCT00420628 Phase 4 loteprednol etabonate/tobramycin opthalmic suspension;vehicle
3 Comparison of Combination Antibiotics Eyedrop to Artificial Tear in Hordeolum After Incision and Curettage Unknown status NCT00534391 Phase 3 neomycin sulfate, polymyxin B sulfate and gramicidin;Artificial tear
4 Chalazia Treatment Study Recruiting NCT02025023 Phase 3 5-fluorouracil Injection;Triamcinolone Acetonide;Triamcinolone Acetonide/5-fluorouracil mixture
5 Effects of Magnetic Therapy and Seawater Combined in Decreasing Intraocular Presion. Unknown status NCT02300818 Phase 1, Phase 2 Seawater eyedrops
6 Generalized Anxiety Disorder Proof of Concept Efficacy and Safety Study of SEP-225441 (Eszopiclone) In GAD Subjects Completed NCT00616655 Phase 2 eszopiclone;eszopiclone;Placebo
7 Chalazion Conservative Treatment Trial Completed NCT01230593 Tobrex Drops and Ointment;Tobradex Drops and Ointment
8 Comparison of DSM-IV-TR and DSM-5 for ASD Completed NCT02296502
9 Enhancing the Public Health Impact of Latent Tuberculosis (TB) Infection Diagnosis and Treatment Active, not recruiting NCT02810678
10 Absorb IV Randomized Controlled Trial Active, not recruiting NCT02173379
11 ABSORB III Randomized Controlled Trial (RCT) Active, not recruiting NCT01751906

Search NIH Clinical Center for Hordeolum

Cochrane evidence based reviews: hordeolum

Genetic Tests for Hordeolum

Anatomical Context for Hordeolum

MalaCards organs/tissues related to Hordeolum:

38
Eye

Publications for Hordeolum

Articles related to Hordeolum:

(show all 20)
# Title Authors Year
1
Hordeolum ( 28723014 )
2017
2
Acupuncture for acute hordeolum. ( 28181687 )
2017
3
Non-surgical interventions for acute internal hordeolum. ( 28068454 )
2017
4
Hordeolum: Acute abscess within an eyelid sebaceous gland. ( 27168505 )
2016
5
Pneumo-orbita mimicking hordeolum. ( 26559044 )
2015
6
Acupuncture for acute hordeolum. ( 25214814 )
2014
7
Hemorrhagic pyogenic granuloma after internal hordeolum. ( 25625065 )
2014
8
Interventions for acute internal hordeolum. ( 23633345 )
2013
9
Current pattern treatment of hordeolum by ophthalmologists in Thailand. ( 21696082 )
2011
10
Interventions for acute internal hordeolum. ( 20824865 )
2010
11
Inadvertent ocular perforation during lid anesthesia for hordeolum removal. ( 17004638 )
2006
12
Effectiveness of combined antibiotic ophthalmic solution in the treatment of hordeolum after incision and curettage: a randomized, placebo-controlled trial: a pilot study. ( 16149682 )
2005
13
Extensive corneal epithelial defect associated with internal hordeolum after uneventful laser in situ keratomileusis. ( 12231335 )
2002
14
Treatment of hordeolum by bloodletting at ear apex. ( 11789331 )
2001
15
Treatment of recurrent hordeolum with Broncasma Berna. ( 10696340 )
1999
16
Staphylococcus aureus hordeolum as a cause of bacteremia and secondary foci. ( 2794893 )
1989
17
Surgical treatment of a chalazion or hordeolum internum. ( 3675336 )
1987
18
External hordeolum (sty) caused by infection with trichophyton mentagrophytes. ( 873673 )
1977
19
Munomycin in hordeolum externum. ( 5923490 )
1966
20
Orbital Cellulitis Following Hordeolum. ( 16692709 )
1925

Variations for Hordeolum

Expression for Hordeolum

Search GEO for disease gene expression data for Hordeolum.

Pathways for Hordeolum

GO Terms for Hordeolum

Biological processes related to Hordeolum according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 8.8 CCL20 PNP TNFRSF8

Sources for Hordeolum

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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