MCID: HRN001
MIFTS: 42

Horner's Syndrome malady

Rare diseases, Neuronal diseases, Eye diseases categories
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Summaries for Horner's Syndrome

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Sources:
21Genetics Home Reference, 43NIH Rare Diseases, 65Wikipedia, 33MalaCards
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NIH Rare Diseases:43 Horner's syndrome consists of miosis (constriction of the pupil), ptosis (drooping of the upper eyelid), anhidrosis (absence of sweating of the face), and enophthalmos (sinking of the eyeball into the eye socket).  it is caused by injury to the sympathetic nerves of the face. in rare cases, horner's syndrome is congenital (present from birth) and associated with a lack of pigmentation of the iris (colored part of the eye). last updated: 3/6/2012

MalaCards: Horner's Syndrome, also known as bernard-horner syndrome, is related to congenital horner syndrome and carotid artery dissection. An important gene associated with Horner's Syndrome is DBH (dopamine beta-hydroxylase (dopamine beta-monooxygenase)). The compounds serine and oligonucleotide have been mentioned in the context of this disorder. Affiliated tissues include eye, testes and thyroid, and related mouse phenotypes are nervous system and cardiovascular system.

Genetics Home Reference:21 Horner syndrome is a disorder that affects the eye and surrounding tissues on one side of the face and results from paralysis of certain nerves. Horner syndrome can appear at any time of life; in about 5 percent of affected individuals, the disorder is present from birth (congenital).

Wikipedia:65 Horner\'s syndrome (also Horner syndrome, Bernard-Horner syndrome, Claude Bernard-Horner syndrome or as... more...

Aliases & Classifications for Horner's Syndrome

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8Disease Ontology, 43NIH Rare Diseases, 21Genetics Home Reference, 10DISEASES, 62UMLS, 58SNOMED-CT, 40NCIt, 35MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Neuronal diseases, Eye diseases


Aliases & Descriptions:

horner's syndrome 8 43 21
bernard-horner syndrome 43 21
oculosympathetic palsy 43 21
horner syndrome 8 21
autonomic nervous system disorder: nos 8
ocular-ophthalmoplegia, sympathetic 62
cervical sympathetic paralysis 8
bernard horner syndrome 8
horner's syndrome pupil 62
von passow syndrome 21
horners syndrome 10
horner's 8


External Ids:

Disease Ontology8 DOID:11486
NCIt40 C28155
MeSH35 D006732
ICD1025 G90.2

Related Diseases for Horner's Syndrome

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Horner's Syndrome:



Diseases related to horner's syndrome

Symptoms for Horner's Syndrome

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Drugs & Therapeutics for Horner's Syndrome

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

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Genetic Tests for Horner's Syndrome

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Anatomical Context for Horner's Syndrome

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33MalaCards
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MalaCards organs/tissues related to Horner's Syndrome:

33
Eye, Testes, Thyroid, Tongue, Breast, B cells, Salivary gland, Lymph node, Lung, Bone, Spinal cord

Animal Models for Horner's Syndrome or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Horner's Syndrome:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00036319.1FLI1, DBH
2MP:00053858.8FLI1, DBH

Publications for Horner's Syndrome

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52PubMed
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Articles related to Horner's Syndrome:

(show top 50)    (show all 491)
idTitleAuthorsYear
1
Horner's syndrome in patients admitted to the paediatric intensive care unit: epidemiology, diagnosis and clinical practice. (23362886)
2013
2
First rib fracture and Horner's syndrome: a rare clinical entity. (23272863)
2013
3
Horner's syndrome following a subtotal thyroidectomy for a benign nodular goitre. (23771972)
2013
4
Physical signs for the general dental practitioner. Case 105. Horner's syndrome. (23971351)
2013
5
First rib fracture and Horner's syndrome due to a motor vehicle collision: a case report. (23830309)
2013
6
Images in vascular medicine. Delayed Horner's syndrome as a presenting symptom of traumatic internal carotid artery dissection and pseudoaneurysm. (21511675)
2011
7
Horner's syndrome--not to be sneezed at. (20189030)
2010
8
Pancoast tumour presenting as paraplegia with Horner's syndrome. (21046878)
2010
9
Hypoglossal nerve palsy, trigeminal nerve palsy and Horner's syndrome in association with epidural block. (19200713)
2009
10
Agenesis of internal carotid artery in a child with ipsilateral Horner's syndrome. (19168824)
2009
11
Bernard-Horner's syndrome: unusual complication after neck dissection. (18355618)
2008
12
Horner's syndrome following internal jugular vein dialysis catheter insertion. (18087133)
2008
13
Delayed Horner's syndrome during a continuous infraclavicular brachial plexus block. (17321929)
2007
14
Oesophageal denture impaction producing Horner's syndrome: a case report. (17625034)
2007
15
Purtscher-like retinopathy and Horner's syndrome following coil embolization of an intracavernous carotid artery aneurysm. (15133679)
2005
16
An unusual vascular cause of Horner's syndrome. (15832022)
2005
17
Horner's syndrome secondary to tube thoracostomy. (15214755)
2004
18
Horner's syndrome as an initial manifestation of Takayasu's arteritis. (12810438)
2003
19
Agenesis of the internal carotid artery associated with aortic arch anomaly in a patient with congenital Horner's syndrome. (12063218)
2002
20
Dysgeusia and painful Horner's syndrome from an internal carotid artery dissection: radiological-anatomical correlation. (12390176)
2002
21
Iatrogenic Horner's syndrome in an experimental pig. (11300674)
2001
22
Horner's syndrome associated with a mandibular symphyseal fracture and bilateral temporomandibular luxation. (11791777)
2001
23
Innervation of sweat glands in the forehead. A study in patients with Horner's syndrome. (11166792)
2001
24
Two cases of reiterated Horner's syndrome after lumbar epidural block. (10981584)
2000
25
Unilateral facial ulceration and Horner's syndrome. (10448475)
1999
26
Persistent Horner's syndrome after spinal fusion and epidural analgesia. A case report. (9507631)
1998
27
Brown-SAcquard syndrome associated with Horner's syndrome in cervical epidural hematoma. (7716632)
1995
28
Congenital Horner's syndrome does not alter Lisch nodule formation. (8285584)
1994
29
Horner's syndrome: an electron microscopic study of a human iris. (1486079)
1992
30
Asymmetry of salivary gland I123 metaiodobenzylguanidine (MIBG) uptake in a patient with cervical neuroblastoma and Horner's syndrome--possible etiologic mechanisms. (1508596)
1992
31
Isolated hypoglossal nerve palsy and Horner's syndrome with benign course. (2030364)
1991
32
Horner's syndrome and trigeminal nerve palsy following epidural anaesthesia for obstetrics. (1914062)
1991
33
Bilateral Horner's syndrome and hoarseness complicating lumbar epidural anesthesia. (2535019)
1989
34
Horner's syndrome and demyelinating peripheral neuropathy caused by high-dose cytosine arabinoside. (2554727)
1989
35
Herpes zoster of second and third segments causing ipsilateral Horner's syndrome. (3111588)
1987
36
Sweat gland and pupillary responsiveness in Horner's syndrome. (3607867)
1987
37
Herpes zoster of second and third segments causing ipsilateral Horner's syndrome. (3115408)
1987
38
Malignant melanomas causing Horner's syndrome in a horse. (3948837)
1986
39
Pulmonary mucormycosis presenting with Horner's syndrome. Report of a medical cure. (3750145)
1986
40
Congenital Horner's syndrome in otolaryngologic practice. (3813984)
1986
41
The diagnosis of Horner's syndrome. Use and limitations of the cocaine test. (3723131)
1986
42
Cranial tumors in aged cattle causing Horner's syndrome and exophthalmos. (6478839)
1984
43
The pericarotid syndrome. A combination of hemicrania, Horner's syndrome, and internal carotid artery wall lesion. (7270271)
1981
44
Pharmacologic localization in Horner's syndrome. (7212003)
1981
45
Of cardiac causalgia, Horner's syndrome, and the cardiac dermatome. (7446399)
1980
46
Evaluation of the causes and accuracy of pharmacologic localization in Horner's syndrome. (7425056)
1980
47
Spontaneous internal carotid dissection, hemicrania, and Horner's syndrome. (508124)
1979
48
Horner's syndrome in childhood. (943049)
1976
49
Horner's syndrome and headache due to carotid artery disease. (1260349)
1976
50
Horner's syndrome as a complication of lumbar epidural block. (1211589)
1975

Variations for Horner's Syndrome

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Expression for genes affiliated with Horner's Syndrome

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Horner's Syndrome

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Pathways for genes affiliated with Horner's Syndrome

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Compounds for genes affiliated with Horner's Syndrome

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45Novoseek
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Compounds related to Horner's Syndrome according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1serine459.1FLI1, DBH
2oligonucleotide458.8FLI1, DBH

GO Terms for genes affiliated with Horner's Syndrome

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Products for genes affiliated with Horner's Syndrome

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Horner's Syndrome

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet