MCID: HRN001
MIFTS: 36

Horner's Syndrome malady

Rare diseases, Neuronal diseases, Eye diseases categories

Summaries for Horner's Syndrome

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NIH Rare Diseases:41 Horner's syndrome consists of miosis (constriction of the pupil), ptosis (drooping of the upper eyelid), and anhidrosis (absence of sweating of the face).  it is caused by injury to the sympathetic nerves of the face. in rare cases, horner's syndrome is congenital (present from birth) and associated with a lack of pigmentation of the iris (colored part of the eye). last updated: 10/1/2014

MalaCards based summary: Horner's Syndrome, also known as horner syndrome, is related to congenital horner syndrome and carotid artery dissection. An important gene associated with Horner's Syndrome is DBH (dopamine beta-hydroxylase (dopamine beta-monooxygenase)). The compounds serine and oligonucleotide have been mentioned in the context of this disorder. Affiliated tissues include eye, testes and thyroid, and related mouse phenotypes are nervous system and cardiovascular system.

Genetics Home Reference:21 Horner syndrome is a disorder that affects the eye and surrounding tissues on one side of the face and results from paralysis of certain nerves. Horner syndrome can appear at any time of life; in about 5 percent of affected individuals, the disorder is present from birth (congenital).

Wikipedia:63 Horner\'s syndrome (also known as Bernard-Horner syndrome and oculosympathetic palsy) is a combination... more...

Aliases & Classifications for Horner's Syndrome

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Horner's Syndrome, Aliases & Descriptions:

Name: Horner's Syndrome 9 41 21
Horner Syndrome 9 21 60
Bernard-Horner Syndrome 41 21
Oculosympathetic Palsy 41 21
Cervical Sympathetic Paralysis 9
 
Horner's Syndrome Pupil 60
Bernard Horner Syndrome 9
Von Passow Syndrome 21
Horners Syndrome 11


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Neuronal diseases, Eye diseases


External Ids:

Disease Ontology9 DOID:11486
NCIt38 C28155
MeSH33 D006732
ICD1025 G90.2

Related Diseases for Horner's Syndrome

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Graphical network of the top 20 diseases related to Horner's Syndrome:



Diseases related to horner's syndrome

Symptoms for Horner's Syndrome

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Drugs & Therapeutics for Horner's Syndrome

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Drug clinical trials:

Search ClinicalTrials for Horner's Syndrome

Search NIH Clinical Center for Horner's Syndrome

Genetic Tests for Horner's Syndrome

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Anatomical Context for Horner's Syndrome

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MalaCards organs/tissues related to Horner's Syndrome:

31
Eye, Testes, Thyroid, Breast, Tongue, Bone, Lymph node, Brain, Lung, Salivary gland, B cells, Spinal cord

Animal Models for Horner's Syndrome or affiliated genes

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MGI Mouse Phenotypes related to Horner's Syndrome:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00036319.1FLI1, DBH
2MP:00053858.8FLI1, DBH

Publications for Horner's Syndrome

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Articles related to Horner's Syndrome:

(show top 50)    (show all 507)
idTitleAuthorsYear
1
Malignant peripheral nerve sheath tumour presenting with Horner's syndrome. (24772708)
2013
2
Horner's syndrome in patients admitted to the paediatric intensive care unit: epidemiology, diagnosis and clinical practice. (23362886)
2013
3
First rib fracture and Horner's syndrome: a rare clinical entity. (23272863)
2013
4
Horner's syndrome following a subtotal thyroidectomy for a benign nodular goitre. (23771972)
2013
5
Physical signs for the general dental practitioner. Case 105. Horner's syndrome. (23971351)
2013
6
First rib fracture and Horner's syndrome due to a motor vehicle collision: a case report. (23830309)
2013
7
Images in vascular medicine. Delayed Horner's syndrome as a presenting symptom of traumatic internal carotid artery dissection and pseudoaneurysm. (21511675)
2011
8
Horner's syndrome--not to be sneezed at. (20189030)
2010
9
Pancoast tumour presenting as paraplegia with Horner's syndrome. (21046878)
2010
10
Hypoglossal nerve palsy, trigeminal nerve palsy and Horner's syndrome in association with epidural block. (19200713)
2009
11
Agenesis of internal carotid artery in a child with ipsilateral Horner's syndrome. (19168824)
2009
12
Bernard-Horner's syndrome: unusual complication after neck dissection. (18355618)
2008
13
Horner's syndrome following internal jugular vein dialysis catheter insertion. (18087133)
2008
14
Delayed Horner's syndrome during a continuous infraclavicular brachial plexus block. (17321929)
2007
15
Oesophageal denture impaction producing Horner's syndrome: a case report. (17625034)
2007
16
Purtscher-like retinopathy and Horner's syndrome following coil embolization of an intracavernous carotid artery aneurysm. (15133679)
2005
17
An unusual vascular cause of Horner's syndrome. (15832022)
2005
18
Horner's syndrome secondary to tube thoracostomy. (15214755)
2004
19
Horner's syndrome as an initial manifestation of Takayasu's arteritis. (12810438)
2003
20
Dysgeusia and painful Horner's syndrome from an internal carotid artery dissection: radiological-anatomical correlation. (12390176)
2002
21
Iatrogenic Horner's syndrome in an experimental pig. (11300674)
2001
22
Horner's syndrome associated with a mandibular symphyseal fracture and bilateral temporomandibular luxation. (11791777)
2001
23
Innervation of sweat glands in the forehead. A study in patients with Horner's syndrome. (11166792)
2001
24
Two cases of reiterated Horner's syndrome after lumbar epidural block. (10981584)
2000
25
Unilateral facial ulceration and Horner's syndrome. (10448475)
1999
26
Persistent Horner's syndrome after spinal fusion and epidural analgesia. A case report. (9507631)
1998
27
Brown-SAcquard syndrome associated with Horner's syndrome in cervical epidural hematoma. (7716632)
1995
28
Congenital Horner's syndrome does not alter Lisch nodule formation. (8285584)
1994
29
Horner's syndrome: an electron microscopic study of a human iris. (1486079)
1992
30
Asymmetry of salivary gland I123 metaiodobenzylguanidine (MIBG) uptake in a patient with cervical neuroblastoma and Horner's syndrome--possible etiologic mechanisms. (1508596)
1992
31
Horner's syndrome in severe tetanus. (1409193)
1992
32
Isolated hypoglossal nerve palsy and Horner's syndrome with benign course. (2030364)
1991
33
Horner's syndrome and trigeminal nerve palsy following epidural anaesthesia for obstetrics. (1914062)
1991
34
Bilateral Horner's syndrome and hoarseness complicating lumbar epidural anesthesia. (2535019)
1989
35
Horner's syndrome and demyelinating peripheral neuropathy caused by high-dose cytosine arabinoside. (2554727)
1989
36
Herpes zoster of second and third segments causing ipsilateral Horner's syndrome. (3111588)
1987
37
Sweat gland and pupillary responsiveness in Horner's syndrome. (3607867)
1987
38
Herpes zoster of second and third segments causing ipsilateral Horner's syndrome. (3115408)
1987
39
Malignant melanomas causing Horner's syndrome in a horse. (3948837)
1986
40
Pulmonary mucormycosis presenting with Horner's syndrome. Report of a medical cure. (3750145)
1986
41
Congenital Horner's syndrome in otolaryngologic practice. (3813984)
1986
42
The diagnosis of Horner's syndrome. Use and limitations of the cocaine test. (3723131)
1986
43
The pericarotid syndrome. A combination of hemicrania, Horner's syndrome, and internal carotid artery wall lesion. (7270271)
1981
44
Pharmacologic localization in Horner's syndrome. (7212003)
1981
45
Of cardiac causalgia, Horner's syndrome, and the cardiac dermatome. (7446399)
1980
46
Evaluation of the causes and accuracy of pharmacologic localization in Horner's syndrome. (7425056)
1980
47
Spontaneous internal carotid dissection, hemicrania, and Horner's syndrome. (508124)
1979
48
Horner's syndrome in childhood. (943049)
1976
49
Horner's syndrome and headache due to carotid artery disease. (1260349)
1976
50
Horner's syndrome as a complication of lumbar epidural block. (1211589)
1975

Variations for Horner's Syndrome

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Expression for genes affiliated with Horner's Syndrome

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Search GEO for disease gene expression data for Horner's Syndrome.

Pathways for genes affiliated with Horner's Syndrome

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Compounds for genes affiliated with Horner's Syndrome

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Sources:
43Novoseek
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Compounds related to Horner's Syndrome according to GeneCards Suite gene sharing:

idCompoundScoreTop Affiliating Genes
1serine439.1FLI1, DBH
2oligonucleotide438.8FLI1, DBH

GO Terms for genes affiliated with Horner's Syndrome

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Products for genes affiliated with Horner's Syndrome

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Sources for Horner's Syndrome

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet