MCID: HRN001
MIFTS: 38

Horner's Syndrome malady

Neuronal category

Summaries for Horner's Syndrome

Sources:
21Genetics Home Reference, 43NIH Rare Diseases, 64Wikipedia, 33MalaCards
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NIH Rare Diseases:43 Horner's syndrome consists of miosis (constriction of the pupil), ptosis (drooping of the upper eyelid), anhidrosis (absence of sweating of the face), and enophthalmos (sinking of the eyeball into the eye socket).  it is caused by injury to the sympathetic nerves of the face. in rare cases, horner's syndrome is congenital (present from birth) and associated with a lack of pigmentation of the iris (colored part of the eye). last updated: 3/6/2012

MalaCards: Horner's Syndrome, also known as bernard-horner syndrome, is related to n syndrome and carotid artery dissection. An important gene associated with Horner's Syndrome is CD6 (CD6 molecule). The compound oligonucleotide have been mentioned in the context of this disorder. Affiliated tissues include tongue, spinal cord and kidney.

Genetics Home Reference:21 Horner syndrome is a disorder that affects the eye and surrounding tissues on one side of the face and results from paralysis of certain nerves. Horner syndrome can appear at any time of life; in about 5 percent of affected individuals, the disorder is present from birth (congenital).

Wikipedia:64 Horner\'s syndrome (also Horner syndrome, Bernard-Horner syndrome, Claude Bernard-Horner syndrome or as... more...

Aliases & Classifications for Horner's Syndrome

Sources:
8Disease Ontology, 43NIH Rare Diseases, 21Genetics Home Reference, 10DISEASES, 61UMLS, 40NCIt, 57SNOMED-CT, 35MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal


Aliases & Descriptions:

horner's syndrome 8 43 21
bernard-horner syndrome 43 21
oculosympathetic palsy 43 21
autonomic nervous system disorder: nos 8
ocular-ophthalmoplegia, sympathetic 61
cervical sympathetic paralysis 8
horner's syndrome pupil 61
bernard horner syndrome 8
von passow syndrome 21
horners syndrome 10
horner syndrome 21
horner's 8


External Ids:

Disease Ontology8 DOID:11486
NCIt40 C28155
MeSH35 D006732
ICD1025 G90.2

Related Diseases for Horner's Syndrome

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Horner's Syndrome:



Diseases related to horner's syndrome

Clinical Features for Horner's Syndrome

Drugs & Therapeutics for Horner's Syndrome

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Horner's Syndrome

Anatomical Context for Horner's Syndrome

Sources:
33MalaCards
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MalaCards organs/tissues related to Horner's Syndrome:

33
Tongue, Spinal cord, Kidney, Lymph node, Lung, Thyroid, Salivary gland, Breast, T cells, B cells, Trigeminal ganglion, Pituitary

Animal Models for Horner's Syndrome or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Horner's Syndrome

Sources:
51PubMed
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Articles related to Horner's Syndrome:

(show top 50)    (show all 537)
idTitleAuthorsYear
1
First rib fracture and Horner's syndrome: a rare clinical entity. (23272863)
2013
2
Internal carotid artery dissection resulting in Horner's syndrome. (23711588)
2013
3
Isolated Horner syndrome and orbital hemangioma. (23629781)
2013
4
Impact of T3 thoracoscopic sympathectomy on pupillary function: a cause of partial Horner's syndrome? (22044979)
2012
5
Horner's syndrome as a complication of percutaneous ethanol treatment of thyroid nodule. (21323592)
2011
6
Pharmacologic testing in Horner's syndrome - a new paradigm. (21081027)
2010
7
Physical signs for the general dental practitioner. Case 64. Horner's syndrome. (19518037)
2009
8
Horner's syndrome and ipsilateral tongue paresis due to carotid artery dissection. (21687168)
2009
9
Malignant peripheral nerve sheath tumor with Horner's syndrome: a case report. (18818575)
2008
10
Pupillary autonomic neuropathy simulating partial Horner syndrome in diabetes mellitus and its reversal with control of blood glucose. (18769297)
2008
11
Oesophageal denture impaction producing Horner's syndrome: a case report. (17625034)
2007
12
Spinal anesthesia for cesarean delivery associated with Horner's syndrome and contralateral trigeminal parasympathetic activation. (17242123)
2007
13
Trigeminal nerve palsy and Horner's syndrome following epidural analgesia for labor: a subdural block? (17270429)
2007
14
Case report of Horner's syndrome complicating internal jugular venous cannulation in a child. (17359414)
2007
15
An unusual vascular cause of Horner's syndrome. (15832022)
2005
16
Neurofibromatosis type 1 presenting with Horner's syndrome. (15272289)
2005
17
"Congenital" Horner's syndrome and carotid dissection. (14569832)
2003
18
Dysgeusia and painful Horner's syndrome from an internal carotid artery dissection: radiological-anatomical correlation. (12390176)
2002
19
Chordoma of the low cervical spine presenting with Horner's syndrome. (12522601)
2002
20
Horner's syndrome: a delayed complication after thoracostomy tube removal. (16093114)
2002
21
Trigeminal and polyradiculoneuritis in a dog presenting with masticatory muscle atrophy and Horner's syndrome. (12102209)
2002
22
Iatrogenic Horner's syndrome in an experimental pig. (11300674)
2001
23
Isolated abducens nerve paresis associated with incomplete Horner's syndrome caused by petrous apex fracture--case report and anatomical study. (11760384)
2001
24
Horner's syndrome secondary to internal jugular catheterization. (11499663)
2001
25
Headache, hypertension and Horner's syndrome. (11064693)
2000
26
Horner's syndrome associated with Neospora infection. (11138858)
2000
27
Horner's syndrome in yolk sac tumour of the mediastinum. (10660315)
1999
28
Transient Horner's syndrome after lumbar epidural anesthesia. (9818887)
1998
29
Just another explanation for: 'Horner's syndrome following low-dose epidural infusion for labour' presented by H. G. W. Paw. (9785085)
1998
30
Intracranial squamous cell carcinoma causing Horner's syndrome in a cow. (9087940)
1997
31
False-negative hydroxyamphetamine (Paredrine) test in acute Horner's syndrome. (8956653)
1996
32
Aneurysmal bone cyst presenting as Horner's syndrome. (7610419)
1995
33
Horner's syndrome and Fuchs' heterochromic uveitis. (7819183)
1994
34
Horner's syndrome secondary to angiogram negative, subadventitial carotid artery dissection. (8467432)
1993
35
Critical evaluation of the cocaine test in the diagnosis of Horner's syndrome. (2310339)
1990
36
Hydroxyamphetamine mydriasis in Horner's syndrome. (2368824)
1990
37
Horner's syndrome after intrapleural anesthesia with bupivacaine for post-herpetic neuralgia. (3188830)
1988
38
Central bilateral sixth nerve palsy associated with a unilateral preganglionic Horner's syndrome. (2971682)
1988
39
Horner's syndrome resulting from a lumbar sympathetic block. (3354900)
1988
40
Herpes zoster of second and third segments causing ipsilateral Horner's syndrome. (3115408)
1987
41
No enophthalmos in Horner's syndrome. (3585371)
1987
42
Malignant melanomas causing Horner's syndrome in a horse. (3948837)
1986
43
Congenital Horner's syndrome in otolaryngologic practice. (3813984)
1986
44
Neurofibroma of the cervical sympathetic chain presenting with Horner's syndrome. (3805885)
1986
45
The 'hatband' sign in Horner's syndrome. (3702017)
1986
46
Upside down ptosis in patients with Horner's syndrome. (6659903)
1983
47
The central corneal thickness in patients with Horner's syndrome. (6624412)
1983
48
Superior oblique paresis and contralateral Horner's syndrome. (6571356)
1983
49
Horner's syndrome due to congenital cytomegalovirus infection. (6277013)
1982
50
Horner's syndrome in the dog and cat as an aid to diagnosis. (1180770)
1975

Genetic Variations for Horner's Syndrome

Expression for genes affiliated with Horner's Syndrome

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Horner's Syndrome

Search GEO for disease gene expression data for Horner's Syndrome.

Pathways for genes affiliated with Horner's Syndrome

Compounds for genes affiliated with Horner's Syndrome

Sources:
45Novoseek
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Compounds related to Horner's Syndrome according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1oligonucleotide458.3GPC3, ETS2, DBH, FLI1

GO Terms for genes affiliated with Horner's Syndrome

Products for genes affiliated with Horner's Syndrome

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Sources for Horner's Syndrome

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet