MCID: HRS011
MIFTS: 35

Horseshoe Kidney malady

Category: Rare diseases

Aliases & Classifications for Horseshoe Kidney

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Aliases & Descriptions for Horseshoe Kidney:

Name: Horseshoe Kidney 47 26

Classifications:



Summaries for Horseshoe Kidney

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Wikipedia:70 Horseshoe kidney, also known as ren arcuatus (in Latin), renal fusion or super kidney, is a congenital... more...

MalaCards based summary: Horseshoe Kidney is related to mucinous adenocarcinoma and peritonitis, and has symptoms including abnormal localization of kidney An important gene associated with Horseshoe Kidney is HNF1B (HNF1 Homeobox B). Affiliated tissues include kidney, bone and colon, and related mouse phenotype normal.

Related Diseases for Horseshoe Kidney

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Diseases related to Horseshoe Kidney via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 278)
idRelated DiseaseScoreTop Affiliating Genes
1mucinous adenocarcinoma30.1CHGA, SYP
2peritonitis30.0KRT20, KRT7
3xanthogranulomatous pyelonephritis30.0CHGA, ENO2
4renal cell carcinoma29.8HNF1B, KRT20, KRT7, NKX2-1, TSC2
5intrahepatic cholangiocarcinoma29.6CDX2, KRT7, NKX2-1
6renal cysts and diabetes syndrome11.1
7joubert syndrome 1810.9
8transient hypogammaglobulinemia of infancy10.6KRT20, NKX2-1
9adult teratoma10.6NKX2-1, SYP
10ovary mixed epithelial carcinoma10.6CHGA, SYP
11malignant peritoneal solitary fibrous tumor10.6ACTC1, NKX2-1
12lice infestation10.6CHGA, SYP
13bone remodeling disease10.6NKX2-1, SYP
14childhood malignant schwannoma10.6CHGA, SYP
15ovarian brenner tumor10.6KRT20, NKX2-1
16microglandular adenosis of breast10.6CHGA, SYP
17clear cell adenoma10.6CHGA, SYP
18osteoblastoma10.6CHGA, SYP
19esophagus adenocarcinoma10.6CHGA, SYP
20fraxf syndrome10.6CHGA, SYP
21froelich syndrome10.6CHGA, SYP
22skin glomangioma10.6ACTC1, SYP
23lumbar plexus neoplasm10.6CHGA, SYP
24pineal parenchymal tumor of intermediate differenciation10.6ACTC1, SYP
25aneurysm10.6
26cutaneous mastocytosis10.6CHGA, SYP
27ependymoblastoma10.5KRT20, SYP
28aortic aneurysm10.5
29diencephalic astrocytomas10.5CHGA, SYP
30iris disease10.5CDX2, KRT20
31abdominal aortic aneurysm10.5
32rectum signet ring adenocarcinoma10.5CHGA, SYP
33appendix adenocarcinoma10.5CDX2, KRT20
34clear cell ependymoma10.5CHGA, SYP
35sarcomatoid renal cell carcinoma10.5HNF1B, KRT7
36appendix lymphoma10.5CDX2, KRT20
37pancreatic agenesis10.5CHGA, SYP
38chronic eustachian salpingitis10.5CDX2, KRT20
39cranial nerve iii tumor10.5CHGA, SYP
40gallbladder adenoma10.5REN, SYP
41tricuspid valve stenosis10.5CHGA, SYP
42benign mesenchymoma10.5CDX2, KRT20
43prostate signet ring cell adenocarcinoma10.4CDX2, KRT20
44oral leukoedema10.4KRT20, KRT7
45pilomyxoid astrocytoma10.4SYP, TSC2
46signet ring basal cell carcinoma10.4KRT20, KRT7
47mediastinal melanocytic neurilemmoma10.4KRT20, KRT7
48cauda equina intradural extramedullary astrocytoma10.4SYP, TSC2
492q33.1 microdeletion syndrome10.4ENO2, SYP
50rectum adenoma10.4KRT20, KRT7

Graphical network of the top 20 diseases related to Horseshoe Kidney:



Diseases related to horseshoe kidney

Symptoms for Horseshoe Kidney

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Human phenotypes related to Horseshoe Kidney:

 63
id Description HPO Frequency HPO Source Accession
1 abnormal localization of kidney63 hallmark (90%) HP:0100542

Drugs & Therapeutics for Horseshoe Kidney

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Drugs for Horseshoe Kidney (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
FludarabineapprovedPhase 1111321679-14-1, 75607-67-930751
Synonyms:
(2R,3S,4S,5R)-2-(6-amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
(2R,3S,4S,5R)-2-(6-amino-2-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
2-F-ARAA
2-F-ara-A
2-Fluoro Ara-A
2-Fluoro-9-beta-D-arabinofuranosyladenine
2-fluoro ARA-A
21679-14-1
9-beta-D-Arabinofuranosyl-2-fluoroadenine
9-beta-D-arabinofuranosyl-2-fluoro-9H-purin-6-amine
9H-Purin-6-amine, 9-beta-D-arabinofuranosyl-2-fluoro- (9CI)
AC1LCW8I
AC1Q51CF
C10H12FN5O4
CCRIS 3382
CHEMBL1568
CID657237
CPD000058874
D07966
EINECS 244-525-5
F-Ara-A
FAMP
FT-0082766
FaraA
Fludara
Fludara, Fludarabine
 
Fludarabina
Fludarabina [Spanish]
Fludarabine
Fludarabine (INN)
Fludarabine 5'-monophosphate
Fludarabine [INN]
Fludarabine monophosphate
Fludarabine phosphate
Fludarabinum
Fludarabinum [Latin]
Fludura
Fluradosa
Fluradosa (TN)
HSDB 6964
I14-4978
LS-15061
MLS000028687
NSC 118218
NSC 118218H
NSC-118218
S1491_Selleck
SAM002548956
SMR000058874
SQ Fludarabine
UNII-1X9VK9O1SC
UNII-P2K93U8740
ZINC04216238
2
alemtuzumabapproved, investigationalPhase 1303216503-57-0
Synonyms:
Campath
 
MabCampath
alemtuzumab
3Immunosuppressive AgentsPhase 112770
4Antimetabolites, AntineoplasticPhase 17171
5AntimetabolitesPhase 111774

Interventional clinical trials:

idNameStatusNCT IDPhase
1Use of Rft5-Dga to Deplete Alloreactive Cells for Pts With Fanconi Anemia After Haploidentical SCTTerminatedNCT00586274Phase 1
2Impact of Low Dose Fluoroscopy in UreteroscopyEnrolling by invitationNCT02704949

Search NIH Clinical Center for Horseshoe Kidney

Genetic Tests for Horseshoe Kidney

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Genetic tests related to Horseshoe Kidney:

id Genetic test Affiliating Genes
1 Horseshoe Kidney26

Anatomical Context for Horseshoe Kidney

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MalaCards organs/tissues related to Horseshoe Kidney:

35
Kidney, Bone, Colon, Pancreas, Testis, Prostate, Lung

Animal Models for Horseshoe Kidney or affiliated genes

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MGI Mouse Phenotypes related to Horseshoe Kidney:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00028737.4ACTC1, CALB2, CDX2, NKX2-1, REN, SYP

Publications for Horseshoe Kidney

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Articles related to Horseshoe Kidney:

(show top 50)    (show all 584)
idTitleAuthorsYear
1
18F-FDG PET/CT in Renal Infections: Evidence of Acute Pyelonephritis in a Horseshoe Kidney. (27879491)
2017
2
Retroperitoneoscopy Technique-Assisted Percutaneous Nephrolithotomy for Complexity Horseshoe Kidney with Renal Stones. (27450075)
2016
3
Laparoscopic heminephrectomy for benign and malignant diseases of the horseshoe kidney. (28073187)
2016
4
Renal cell carcinoma in a horseshoe kidney: Report of a rare disease. (28000646)
2016
5
Polycystic horseshoe kidney. (26265824)
2015
6
Mucinous cystadenoma of a horseshoe kidney: A case report and literature review. (25624964)
2015
7
Rare coexistence of mediastinal hepatoid adenocarcinoma, idiopathic azoospermia and horseshoe kidney: a case report and review of the literature. (26617920)
2015
8
Anomalous inferior vena cava associated with horseshoe kidney on multidetector computed tomography. (23849103)
2013
9
Wandering spleen in an adult man associated with the horseshoe kidney. (24693523)
2013
10
Laparoscopic Anderson-Hynes pyeloplasty without symphysiotomy for hydronephrosis with horseshoe kidney. (23710906)
2013
11
Renal cell carcinoma in a horseshoe kidney: radiology and pathology correlation. (23814684)
2013
12
Giant renal calculus in a horseshoe kidney presenting as an abdominal lump. (21249492)
2011
13
Percutaneous endovascular repair of abdominal aortic aneurysm with coexisting horseshoe kidney: technical aspects and review of the literature. (23204827)
2011
14
Venous anomalies and horseshoe kidney. A minefield in open vascular surgery. (22067928)
2011
15
Squamous cell carcinoma within a horseshoe kidney with associated renal stones detected by computed tomography and magnetic resonance imaging. (20801492)
2011
16
Horseshoe kidney with cysts and a single ureter: a case report. (21541456)
2010
17
Ureteropelvic junction obstruction and calyceal diverticulum in a child with Turner syndrome and horseshoe kidney. (20843761)
2010
18
Renal cell carcinoma in a horseshoe kidney. (19504996)
2009
19
New case of an infrarenal abdominal aortic aneurysm associated with horseshoe kidney. (20096188)
2009
20
Drainage characteristics and differential function of the horseshoe kidney: what is typical? (18484886)
2008
21
Neurofibromatosis type 1 with intracranial hemorrhage and horseshoe kidney. (18805374)
2008
22
Optimal scintigraphic evaluation of a hydronephrotic horseshoe kidney. (18055697)
2007
23
Laparoscopic nephrectomy for a girl with giant hydronephrosis of a horseshoe kidney. (17645611)
2007
24
Split technique in horseshoe kidney transplantation. (16825807)
2006
25
Adrenocortical carcinoma with renal vein invasion in a woman with a horseshoe kidney. (17113906)
2006
26
Isthmus of a horseshoe kidney overlying a ruptured abdominal aortic aneurysm: a case report. (16702941)
2006
27
Diagnostic and treatment of renovascular hypertension in the patient with horseshoe kidney]. (15909888)
2005
28
Morphological observation of the horseshoe kidney with special reference to the vascular system in 2 Japanese cadavers. (16350421)
2005
29
Abdominal aortic surgery and horseshoe kidney. (15599631)
2004
30
Horseshoe kidney with a circumcaval ureter. (15669596)
2004
31
The renal impact of aortic stent-grafting in patients with a horseshoe kidney. (15578140)
2004
32
Use of horseshoe kidney as renal transplant from living donor: its surgical feasibility and pitfalls. (11119848)
2000
33
Special considerations in endopyelotomy in a horseshoe kidney. (8638374)
1996
34
Tumor in the horseshoe kidney: clinical implications and review of embryogenesis. (1552596)
1992
35
Antenatal diagnosis of horseshoe kidney. (1608088)
1992
36
In utero detection of horseshoe kidney with unilateral multicystic dysplasia. (1441041)
1992
37
Abdominal aortic aneurysm in association with horseshoe kidney. (1765712)
1991
38
Aortic surgery and horseshoe kidney: a challenging surgical problem. (3664411)
1987
39
An unusual case of Wilms' tumour in a horseshoe kidney. (3008464)
1986
40
Abdominal aortic surgery & horseshoe kidney. (3807096)
1986
41
Primary renal actinomycosis in the presence of horseshoe kidney. (3779366)
1986
42
The radionuclide diagnosis of horseshoe kidney. (3000677)
1985
43
Horseshoe kidney in one of identical twin girls. (4040178)
1985
44
Ruptured abdominal aortic aneurysm with horseshoe kidney. (6502842)
1984
45
Dyskeratosis congenita with pancytopenia and horseshoe kidney. (6710212)
1984
46
Horseshoe kidney mimicking adenopathy. (6612914)
1983
47
Adenocarcinoma of the pelvis of a horseshoe kidney. (7426954)
1980
48
Abdominal aortic aneurysm and horseshoe kidney. A different perspective. (454180)
1979
49
Complications of horseshoe kidney. (1162813)
1975
50
Multilocular cystic dysplasia of half of a horseshoe kidney. (4844002)
1974

Variations for Horseshoe Kidney

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Expression for genes affiliated with Horseshoe Kidney

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Search GEO for disease gene expression data for Horseshoe Kidney.

Pathways for genes affiliated with Horseshoe Kidney

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GO Terms for genes affiliated with Horseshoe Kidney

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Biological processes related to Horseshoe Kidney according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1regulation of blood volume by renin-angiotensinGO:00020169.7NKX2-1, REN
2endoderm developmentGO:00074929.6HNF1B, NKX2-1

Sources for Horseshoe Kidney

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet