Aliases & Classifications for Horseshoe Kidney

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Aliases & Descriptions for Horseshoe Kidney:

Name: Horseshoe Kidney 45

Classifications:



Summaries for Horseshoe Kidney

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Wikipedia:68 Horseshoe kidney, also known as ren arcuatus (in Latin), renal fusion or super kidney, is a congenital... more...

MalaCards based summary: Horseshoe Kidney is related to renal cysts and diabetes syndrome and joubert syndrome 18, and has symptoms including abnormal localization of kidney An important gene associated with Horseshoe Kidney is HNF1B (HNF1 Homeobox B). Affiliated tissues include kidney, t cells and lung, and related mouse phenotype renal/urinary system.

Related Diseases for Horseshoe Kidney

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Graphical network of the top 20 diseases related to Horseshoe Kidney:



Diseases related to horseshoe kidney

Symptoms for Horseshoe Kidney

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HPO human phenotypes related to Horseshoe Kidney:

id Description Frequency HPO Source Accession
1 abnormal localization of kidney hallmark (90%) HP:0100542

Drugs & Therapeutics for Horseshoe Kidney

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Drugs for Horseshoe Kidney (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
alemtuzumabapproved, investigationalPhase 1302216503-57-0
Synonyms:
Campath
 
Lemtrada
Mabcampath
alemtuzumab
2
FludarabineapprovedPhase 1105921679-14-1, 75607-67-930751
Synonyms:
(2R,3S,4S,5R)-2-(6-amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
(2R,3S,4S,5R)-2-(6-amino-2-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
2-F-ara-A
2-Fluoro Ara-A
2-Fluoro-9-beta-D-arabinofuranosyladenine
2-Fluoro-ara AMP
2-Fluoroadenine arabinoside 5'-monophosphate
21679-14-1
2F-Ara-AMP
9-beta-Arabinofuranosyl-2-fluoroadenine-5'-phosphate
9-beta-D-Arabinofuranosyl-2-fluoroadenine
9-beta-D-Arabinofuranosyl-2-fluoroadenine 5'-(dihydrogen phosphate)
9-beta-D-Arabinofuranosyl-2-fluoroadenine 5'-monophosphate
9-beta-D-arabinofuranosyl-2-fluoro-9H-purin-6-amine
9H-Purin-6-amine, 9-beta-D-arabinofuranosyl-2-fluoro- (9CI)
AC1LCW8I
AC1Q51CF
C10H12FN5O4
CCRIS 3382
CHEMBL1568
CID657237
CPD000058874
D07966
EINECS 244-525-5
F-Ara-A
FAMP
FT-0082766
FaraA
Fludara
 
Fludara, Fludarabine
Fludarabina
Fludarabina [Spanish]
Fludarabine
Fludarabine (INN)
Fludarabine 5'-monophosphate
Fludarabine Phosphate
Fludarabine [INN]
Fludarabine monophosphate
Fludarabine phosphate
Fludarabinum
Fludarabinum [Latin]
Fludura
Fluradosa
Fluradosa (TN)
HSDB 6964
I14-4978
LS-15061
MLS000028687
NSC 118218
NSC 118218H
NSC-118218
Oforta
S1491_Selleck
SAM002548956
SMR000058874
SQ Fludarabine
UNII-1X9VK9O1SC
UNII-P2K93U8740
ZINC04216238
3Fludarabine phosphatePhase 1105930751

Interventional clinical trials:

idNameStatusNCT IDPhase
1Use of Rft5-Dga to Deplete Alloreactive Cells for Pts With Fanconi Anemia After Haploidentical SCTTerminatedNCT00586274Phase 1
2Impact of Low Dose Fluoroscopy in UreteroscopyEnrolling by invitationNCT02704949

Search NIH Clinical Center for Horseshoe Kidney

Genetic Tests for Horseshoe Kidney

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Anatomical Context for Horseshoe Kidney

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MalaCards organs/tissues related to Horseshoe Kidney:

33
Kidney, T cells, Lung, Breast, Brain, Prostate, Bone

Animal Models for Horseshoe Kidney or affiliated genes

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MGI Mouse Phenotypes related to Horseshoe Kidney:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.6HNF1B, REN, TSC2

Publications for Horseshoe Kidney

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Articles related to Horseshoe Kidney:

(show top 50)    (show all 550)
idTitleAuthorsYear
1
Neonatal hypotonia. (26042909)
2015
2
Bilateral tarsal tunnel syndrome related to intense cycling activity: proposal of a multimodal diagnostic approach. (26044912)
2015
3
Matrix metalloproteinase 10 contributes to hepatocarcinogenesis in a novel crosstalk with the stromal derived factor 1/C-X-C chemokine receptor 4 axis. (25808184)
2015
4
Recurrent cerebral amyloid angiopathy-related hemorrhage. (25675016)
2015
5
Lack of association between autonomously functioning thyroid nodules and germline polymorphisms of the thyrotropin receptor and GI+s genes in a mild to moderate iodine-deficient Caucasian population. (24789540)
2014
6
Computational and functional characterization of angiogenin mutations, and correlation with amyotrophic lateral sclerosis. (25372031)
2014
7
Granulocytic myeloid-derived suppressor cells are cryosensitive and their frequency does not correlate with serum concentrations of colony-stimulating factors in head and neck cancer. (23160385)
2013
8
Association between the receptor for advanced glycation end products gene polymorphisms and coronary artery disease. (24078092)
2013
9
Uterine endometrial carcinoma: 10 years' experience with long-term follow-up at a single Korean institution. (23075517)
2012
10
Regulation of phosphatidylinositol-5-phosphate signaling by Pin1 determines sensitivity to oxidative stress. (23193159)
2012
11
Hypoglycaemia is more frequent in type 2 diabetic patients with co-morbid vascular disease: an analysis of the DiaRegis registry. (21628353)
2012
12
Stanniocalcin supports the functional adaptation of adult-sized kidneys transplanted into the pediatric recipients. (22588538)
2012
13
Drug susceptibility pattern of Mycobacterium tuberculosis isolates from patients of category-II failure of pulmonary tuberculosis under directly observed treatment short-course from north India. (22890158)
2012
14
Tissue factor pathway inhibitor 2 is induced by thrombin in human macrophages. (21515313)
2011
15
Reduced tumor lysis syndrome with low dose chemotherapy for hyperleukocytic acute leukemia prior to induction therapy. (22126570)
2011
16
Aberrations of NEGR1 on 1p31 and MYEOV on 11q13 in neuroblastoma. (21624008)
2011
17
Letter: Aquagenic keratoderma: successful treatment with botulinum toxin. (20402952)
2010
18
Identification and inhibitory properties of a novel Ca(2+)/calmodulin antagonist. (20392081)
2010
19
Severe hyponatremia due to ACTH insufficiency in a 14 year-old girl with growth hormone deficiency. (20432824)
2010
20
Genetic polymorphisms in the PTPN13 gene and risk of squamous cell carcinoma of head and neck. (19892796)
2009
21
Regulation of cation channel voltage and Ca2+ dependence by multiple modulators. (19386758)
2009
22
Link between allergic asthma and airway mucosal infection suggested by proteinase-secreting household fungi. (19710638)
2009
23
Association of IL-6 gene polymorphism with the outcome of allogeneic haematopoietic stem cell transplantation in Czech patients. (18976446)
2008
24
Neurochemical markers of brain damage in cerebrospinal fluid during induction treatment of acute lymphoblastic leukemia in children. (17973312)
2008
25
Association of the met66 allele of brain-derived neurotrophic factor (BDNF) with smoking. (17186223)
2007
26
Superoxide dismutase as a target enzyme for Fe-porphyrin-induced cell death. (17112592)
2007
27
The relationship of hypocalcemic convulsions related to nutritional rickets with age, gender, season, and serum phosphorus levels. (21857550)
2007
28
Lymphocyte-white blood cell count ratio: a quickly available screening tool to differentiate acute purulent tonsillitis from glandular fever. (17224526)
2007
29
N-acetylgalactosamine-6-sulfatase protein detection in MPS IVA patient and unaffected control samples. (17027703)
2007
30
Dynamic cytoplasmic anchoring of the transcription factor Bach1 by intracellular hyaluronic acid binding protein IHABP. (15809329)
2005
31
Molluscum contagiosum-like lesions in lepromatous leprosy. (15267197)
2003
32
P53 protein and malignant progression in Barrett's metaplasia (Barrett's esophagus). (12809848)
2003
33
Glycogen synthase kinase-3 and Axin function in a beta-catenin-independent pathway that regulates neurite outgrowth in neuroblastoma cells. (14664817)
2003
34
Response of tumour necrosis factor-alpha to delayed in vitro monocyte stimulation in patients with septic shock is related to outcome. (11869172)
2002
35
Evolution of vertebrate neuropeptides. (11595356)
2001
36
Cyclic neutropenia. Detection of a mutation in the gene for neutrophil elastase (ELA2)]. (11572070)
2001
37
Implications in the maintenance of pregnancy: I. Presence of immunoreactive glycodelin in human umbilical cord vein endothelial cells. (10731550)
2000
38
Malignant hypertension with a rare complication of pulmonary alveolar hemorrhage. (10644871)
2000
39
Retrovirally expressed human arylsulfatase A corrects the metabolic defect of arylsulfatase A-deficient mouse cells. (10822308)
2000
40
Cytokines TNF-alpha and GM-CSF in BAL from two different segments of lungs defined by high resolution computerized tomography (HRCT) in patients with sarcoidosis]. (11200748)
2000
41
Localization of the ROMK protein on apical membranes of rat kidney nephron segments. (9374837)
1997
42
Urinary methylmalonic acid to detect vitamin B12 deficiency. (7723154)
1995
43
Intraoperative radiation therapy for locally advanced recurrent rectal or rectosigmoid cancer. (7564378)
1995
44
Rabbit IgG cross-reacts with Alzheimer neurofibrillary tangles. (8059596)
1994
45
Sequence similarity of phospholipase A2 activating protein and the G protein beta-subunits: a new concept of effector protein activation in signal transduction? (8236442)
1993
46
Intravenous urography with iopamidol in children with reflux and obstructive nephropathy: effects on glomerular and tubular functions and the renin-angiotensin-aldosterone system. (2205271)
1990
47
Plasma norepinephrine kinetics, dopamine-beta-hydroxylase, and chromogranin-A, in hypothyroid patients before and following replacement therapy. (2294136)
1990
48
Pustulosis palmoplantaris and its relation to chronic recurrent multifocal osteomyelitis. (478042)
1979
49
Papilledema related to left cerebral hemisphere abscess in a heifer. (4491122)
1973
50
Epilepsy with fetishism relieved by temporal lobectomy. (13202455)
1954

Variations for Horseshoe Kidney

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Expression for genes affiliated with Horseshoe Kidney

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Search GEO for disease gene expression data for Horseshoe Kidney.

Pathways for genes affiliated with Horseshoe Kidney

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GO Terms for genes affiliated with Horseshoe Kidney

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Biological processes related to Horseshoe Kidney according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1response to drugGO:00424938.9ACTC1, HNF1B, REN

Sources for Horseshoe Kidney

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet