Aliases & Classifications for Htlv-1 Associated Myelopathy

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Sources:
65UMLS, 46NINDS, 47Novoseek
See all sources

Aliases & Descriptions for Htlv-1 Associated Myelopathy:

Name: Htlv-1 Associated Myelopathy 46
Myelopathy, Htlv-1-Associated 47
 
Tropical Spastic Paraparesis 65


Summaries for Htlv-1 Associated Myelopathy

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NINDS:46 For several decades the term ?tropical spastic paraparesis? (TSP) has been used to describe a chronic and progressive disease of the nervous system that affects adults living in equatorial areas of the world and causes

MalaCards based summary: Htlv-1 Associated Myelopathy, also known as myelopathy, htlv-1-associated, is related to htlv-1 associated myelopathy/tropical spastic paraparesis and tropical spastic paraparesis, and has symptoms including myelopathy, spastic paraparesis and abnormal pyramidal signs. An important gene associated with Htlv-1 Associated Myelopathy is CNTN2 (Contactin 2 (Axonal)), and among its related pathways are and Immune response_MIF-mediated glucocorticoid regulation. Affiliated tissues include t cells, spinal cord and b cells.

Related Diseases for Htlv-1 Associated Myelopathy

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Diseases related to Htlv-1 Associated Myelopathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 81)
idRelated DiseaseScoreTop Affiliating Genes
1htlv-1 associated myelopathy/tropical spastic paraparesis11.0
2tropical spastic paraparesis11.0
3spastic paraparesis11.0
4spasticity11.0
5dermatitis10.5
6human t-cell leukemia virus type 110.5
7aplastic anemia10.5
8leukemia10.5
9myelitis10.5
10spinal cord disease10.5
11t-cell leukemia10.5
12neurologic diseases10.5
13infective dermatitis associated with htlv-110.5
14mucolipidosis ii alpha/beta10.4
15muscle tissue disease10.4
16myopathy10.4
17viral infectious disease10.4
18stroke, ischemic10.2
19leprosy10.2
20adult t-cell leukemia10.2
21muscle disorders10.2
22paroxysmal nocturnal hemoglobinuria10.2
23lepromatous leprosy10.2
24adjustment disorder10.2
25amyloidosis10.2
26bone structure disease10.2
27central nervous system disease10.2
28hemoglobinuria10.2
29nervous system disease10.2
30neuromuscular disease10.2
31neuropathy10.2
32non-suppurative otitis media10.2
33peripheral nervous system disease10.2
34peripheral neuropathy10.2
35thyroiditis10.2
36polymyositis10.2
37autonomic dysfunction10.2
38hypertonia10.2
39human t-cell leukemia virus type 210.1CNTN2, JUN
40rectosigmoid cancer10.1HLA-A, IL2RA
41limited scleroderma10.1HLA-A, IL2RA
42atypical lipomatous tumor10.1HLA-A, IL2RA
43baby rattle pelvic dysplasia10.0IL2RA, MYC
44xanthogranulomatous pyelonephritis10.0HLA-A, IL2
45hemolytic anemia10.0HLA-A, IL2
46succinate-coa ligase deficiency10.0HLA-A, IL2
47spotted fever10.0HLA-A, IL2
48graft-versus-host disease, protection against9.9IL2, IL2RA
49cervix endometrial stromal tumor9.9IL2, IL2RA
50cd45 deficiency9.9IL2, IL2RA

Graphical network of the top 20 diseases related to Htlv-1 Associated Myelopathy:



Diseases related to htlv-1 associated myelopathy

Symptoms for Htlv-1 Associated Myelopathy

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HPO human phenotypes related to Htlv-1 Associated Myelopathy:

id Description Frequency HPO Source Accession
1 myelopathy HP:0002196
2 spastic paraparesis HP:0002313
3 abnormal pyramidal signs HP:0007256

Drugs & Therapeutics for Htlv-1 Associated Myelopathy

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Drugs for Htlv-1 Associated Myelopathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Lamivudineapproved, investigationalPhase 2, Phase 3575134678-17-460825
Synonyms:
(+/-) (Cis)-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
(+/-)-3TC
(+/-)-BCH-189
(+/-)-SddC
(-)-(2'R,5'S)-1-[2'-Hydroxymethyl-5'-(1,3-oxathiolanyl)]cytosine
(-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine
(-)-1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
(-)-2'-Deoxy-3'-thiacytidine
(-)-BCH 189
(-)-BCH-189
(-)-SddC
(-)-beta-L-2',3'-Dideoxy-3'-thiacytidine
(-)NGPB-21
(2R,cis)-4-amino-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one
.beta.-L-(-)-2',3'-dideoxy-3'-thiacytidine & Sho-Saiko-To
134678-17-4
2',3' Dideoxy 3' thiacytidine
2',3'-Dideoxy-3'-thiacytidine
2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (+/-) (Cis)
2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S)
2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S) & Galanthus Nivalis Agglutinin (GNA)
2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S) & Hippeastrum hybrid agglutinin( HHA)
3'-Thia-2',3'-dideoxycytidine
3-TC
3TC
3TC & GNA
3TC & SST
3TC (AIDS INITIATIVE) (AIDS INITIATIVE)
3TC and NV-01
3TC, Zeffix, Heptovir, Epivir, Epivir-HBV, Lamivudine
4-Amino-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone
4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one
4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
480434-79-5
AC-1416
AC1L1TZZ
AC1Q6C34
BCH 189
BCH-189
BCH-790
BCH189
BIDD:GT0033
Bio-0652
C07065
C8H11N3O3S
CCRIS 9274
CHEBI:133986
CHEMBL141
CID60825
CPD000466319
D00353
D019259
DB00709
 
DRG-0126
DTHC
Epivir
Epivir (TN)
Epivir HBV
Epivir(TM)
Epivir-HBV
Epzicom
FT-0082667
GG-714
GR 109714 X
GR 109714X
GR-109714X
GR109714X
HHA & 3TC
HHA & Lamivudine
HMS2051D21
HSDB 7155
Hepitec
Heptivir
Heptodin
Heptovir
L0217
LMV
LS-2107
Lamivir
Lamivudin
Lamivudina
Lamivudine
Lamivudine & GNA
Lamivudine (JAN/USP/INN)
Lamivudine [USAN:BAN:INN]
Lamivudine [USAN:INN:BAN]
Lamivudine [Usan:Ban:Inn]
Lamivudine, (2S-cis)-Isomer
Lamivudinum
MLS000759424
MLS001424097
MolPort-002-507-347
NCGC00159341-03
NCGC00159341-04
NSC620753
S1706_Selleck
SAM001246582
SAM002589994
SMR000466319
STK801940
UNII-2T8Q726O95
ZINC00012346
Zeffix
Zefix
beta-L-2',3'-Dideoxy-3'-thiacytidine
beta-L-3'-Thia-2',3'-dideoxycytidine
lamivudine
2
Pentoxifyllineapproved, investigationalPhase 3886493-05-64740
Synonyms:
1,2,3,6-Tetrahydro-3,7-dimethyl-1-(5-oxohexyl)-2,6-purindion
1-(5-Oxohexyl)-3,7-dimethylxanthine
1-(5-Oxohexyl)theobromine
2a3c
3,7-Dihydro-3,7-dimethyl-1-(5-oxohexyl)-1H-purine-2,6-dione
3,7-Dimethyl-1-(5-oxo-hexyl)-3,7-dihydro-purine-2,6-dione
3,7-Dimethyl-1-(5-oxohexyl) xantine
3,7-Dimethyl-1-(5-oxohexyl)-1H,3H-purin-2,6-dione
3,7-Dimethyl-1-(5-oxohexyl)-3,7-dihydro-1H-purine-2,6-dione
3,7-Dimethyl-1-(5-oxohexyl)xanthine
3,7-Dimethyl-1-(5-oxohexyl)xantine
3,7-dimethyl-1-(5-oxohexyl)purine-2,6-dione
5-26-14-00081 (Beilstein Handbook Reference)
6493-05-6
AB00052363
AC1L1IUN
AKOS000541484
Agapurin
Agapurin Retard
Azupentat
BAS 00897429
BB_SC-2111
BIDD:GT0174
BL 191
BL-191
BL191
BPBio1_000167
BRD-K57569181-001-05-1
BRN 0558929
BSPBio_000151
BSPBio_003439
C07424
C13H18N4O3
CAS-1677687
CCRIS 6832
CHEMBL628
CID4740
CPD000035998
D00501
D010431
DB00806
Dimethyloxohexylxanthine
DivK1c_000729
Durapental
EHT 0201
EHT-0201
EHT-201
EHT0201
EINECS 229-374-5
EU-0100936
HMS1568H13
HMS1922E16
HMS2051N06
HMS2090H13
HMS2093G21
HMS502E11
Hemovas
I06-1592
IDI1_000729
IN1161
Ikomio
KBio1_000729
KBio2_001924
KBio2_004492
KBio2_007060
KBio3_002942
KBioGR_000893
KBioSS_001924
LS-149385
 
Lopac-P-1784
Lopac0_000936
MLS000079026
MLS000758298
MLS001201764
MolPort-001-823-263
NCGC00015801-01
NCGC00015801-02
NCGC00015801-04
NCGC00015801-10
NCGC00067069-02
NCGC00067069-03
NCGC00067069-04
NCGC00067069-05
NCGC00178062-01
NCGC00178062-02
NINDS_000729
NSC 637086
NSC637086
Oxpentifylline
P 1784
PDSP1_001015
PDSP2_000999
PENTOXYPHYLINE
PNX
Pentoxifilina
Pentoxifilina [INN-Spanish]
Pentoxifyllin
Pentoxifylline
Pentoxifylline (JAN/USP/INN)
Pentoxifylline [USAN:INN:JAN]
Pentoxifyllinum
Pentoxifyllinum [INN-Latin]
Pentoxil
Pentoxil (TN)
Pentoxiphyllin
Pentoxiphylline
Pentoxiphyllium
Pentoxyfylline
Pentoxyphyllin
Pentoxyphylline
Prestwick0_000196
Prestwick1_000196
Prestwick2_000196
Prestwick3_000196
Prestwick_608
Px
Ralofect
Rentylin
SAM001247011
SMR000035998
SPBio_001221
SPBio_002072
SPECTRUM1503611
SR-01000075641-4
STK177321
Spectrum2_001181
Spectrum3_001820
Spectrum4_000227
Spectrum5_001161
Spectrum_001444
Torental
Trental
Trental (TN)
UNII-SD6QCT3TSU
Vasofirin
Vazofirin
ZINC01530776
cis-9-Octadecenoyl coenzyme A
pentoxifylline
3
Miconazoleapproved, investigationalPhase 2, Phase 3291222916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
Desenex
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Makesense
Micantin (nitrate)
Micatin
 
Miconasil Nitrate
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Oravig
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
Rash Relief Antifungal
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
4
Valproic Acidapproved, investigationalPhase 330299-66-13121
Synonyms:
(N-C3H7)2CHCOOH
(S)-2-propyl-4-pentanoate
(S)-2-propyl-4-pentanoic acid
2 PP (base)
2-N-Propyl-N-valeric acid
2-PROPYL-pentanoic acid
2-Propyl-Pentanoate
2-Propyl-Pentanoic acid
2-Propylpentanoate
2-Propylpentanoic Acid
2-Propylpentanoic acid
2-Propylvaleric Acid
2-Propylvaleric acid
2-n-Propyl-n-valeric acid
2-n-propyl-n-valeric acid
2-propylvaleric acid
4-Heptanecarboxylic acid
4-heptanecarboxylic acid
76584-70-8 (hydrochloride salt (2:1))
99-66-1
AC1L1F7T
AC1Q2ULA
AI3-10500
APO-divalproex
Abbott 44090
Acide valproique
Acide valproique [INN-French]
Acide valproique [inn-french]
Acido valproico
Acido valproico [INN-Spanish]
Acido valproico [inn-spanish]
Acidum valproicum
Acidum valproicum [INN-Latin]
Acidum valproicum [inn-latin]
Alti-Valproic
Alti-valproic
Apo-valproic
Apo-valproic syrup
Avugane
BIDD:GT0858
BRN 1750447
Baceca
C07185
CHEBI:39867
CHEMBL109
CID3121
CPD000499581
Convulex
Convulsofin
D00399
DB00313
DOM-divalproex
DOM-valproic
DOM-valproic acid E.C.
DPA
Delepsine
Depacon
Depakene
Depakene (TN)
Depakin
Depakin chrono
Depakine
Depakine chrono
Depakote
Depakote (TM)
Depakote ER
Deproic
Di-N-propylacetic acid
Di-N-propylessigsaeure
Di-N-propylessigsaure
Di-N-propylessigsaure [german]
Di-n-propylacetic acid
Di-n-propylessigsaeure
Di-n-propylessigsaure
Di-n-propylessigsaure [German]
Di-n-propylessigsäure
Dipropyl Acetate
Dipropylacetate
Dipropylacetic acid
DivK1c_000273
Divalproex
Dom-Valproic
Dom-valproate
Dom-valproic acid
Dom-valproic acid syrup
EINECS 202-777-3
Epiject I.V.
Epilex
Epilim
Epival
Epival er
Ergenyl
G2M-777
Gen-divalproex
HMS2089J06
HSDB 3582
I04-0211
InChI=1/C8H16O2/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H,9,10)
KBio1_000273
KBio2_001001
KBio2_002277
KBio2_003569
KBio2_004845
 
KBio2_006137
KBio2_007413
KBio3_002626
KBio3_002757
KBioGR_000871
KBioGR_002277
KBioSS_001001
KBioSS_002278
Kyselina 2-propylvalerova
Kyselina 2-propylvalerova [Czech]
LS-161170
LS-2068
MLS001076682
MLS001335927
MLS001335928
MLS002415770
Med Valproic
Med valproic
MolPort-001-791-895
Mylproin
Myproate
Myproic Acid
Myproic acid
N-DPA
N-Dipropylacetic acid
NCGC00091149-01
NCGC00091149-02
NCGC00091149-03
NCGC00091149-04
NINDS_000273
NSC 93819
NSC93819
Novo-Valproic
Novo-Valproic - ECC
Novo-divalproex
Novo-valproic
Novo-valproic soft gel cap
Nu-Valproic
Nu-valproic
P0823
P6273_SIGMA
PEAC
PHL-valproate
PHL-valproic acid
PHL-valproic acid E.C.
PMS-Divalproex
PMS-Valproic Acid
PMS-valproate
PMS-valproic acid
PMS-valproic acid E.C.
Penta-Valproic
Penta-valproic
Propylvaleric acid
Ratio-Valproic - ECC
S(-)-4-En-valproate
S(-)-4-En-valproic acid
S-2-N-Propyl-4-pentenoate
S-2-N-Propyl-4-pentenoic acid
SAM002564230
SBB065764
SMR000499581
SPBio_000912
Sandoz valproic
Savicol
Semisodium Valproate
Sodium hydrogen divalproate
Spectrum2_000946
Spectrum3_001733
Spectrum4_000376
Spectrum_000521
Sprinkle
Stavzor
UNII-614OI1Z5WI
VALPROIC ACID
VALPROIC acid
VPA
Valcote
Valparin
Valproate
Valproate Semisodium
Valproate semisodique [French]
Valproate semisodium
Valproato semisodico [Spanish]
Valproatum seminatricum [Latin]
Valproic
Valproic Acid
Valproic Acid, Sodium Salt (2:1)
Valproic acid
Valproic acid (USP)
Valproic acid USP
Valproic acid USP24
Valproic acid [USAN:INN:BAN]
Valproic acid [usan:ban:inn]
Valproinsaeure
Valproinsäure
Vupral
WLN: QVY3 & 3
di-n-propylacetic acid
n-DPA
n-Dipropylacetic acid
nchembio.79-comp4
nchembio815-comp21
valproate
valproic acid
5
ZidovudineapprovedPhase 2, Phase 348930516-87-135370
Synonyms:
-Azido-3&prime
-deoxythymidine
1-(3-Azido-2,3-dideoxy-beta-D-ribofuranosyl)thymine
3&prime
3' Azido 2',3' Dideoxythymidine
3' Azido 3' deoxythymidine
3'-Azido-2',3'-Dideoxythymidine
3'-Azido-3'-deoxythymidine
3'-Azido-3'-deoxythymidine & Concanavalin A
3'-Azido-3'-deoxythymidine & Erythropoietin
3'-Azido-3'-deoxythymidine & Heteropolyoxotungstate PM-19
3'-Azido-3'-deoxythymidine & Interleukin-1
3'-Azido-3'-deoxythymidine & Interleukin-2
3'-Azido-3'-deoxythymidine & Interleukin-6
3'-Azido-3'-deoxythymidine & Lithium & Erythropoietin
3'-Azido-3'-deoxythymidine & Lithium & Interleukin-1
3'-Azido-3'-deoxythymidine & Lithium & Interleukin-6
3'-Azido-3'-deoxythymidine & Lymphoblastoid Interferon
3'-Azido-3'-deoxythymidine & Sho-Saiko-To
3'-Azido-3'-deoxythymidine (AIDS)
3'-Azido-3'deoxythymidine & Interferon .alpha.
3'-Azidothymidine
3'-Deoxy-3'-azidothymidine
3'-azido-3'-deoxythymidine, AZT
3-Azido-3-deoxythymidine
30516-87-1
399024-19-2
A2169_SIGMA
AC1L1TKL
AC1Q2OEK
AZT
AZT & CD4(178)-PE 40
AZT & Colony-stimulating factor 2
AZT & Concanavalin A (ConA)
AZT & EPO
AZT & GM-CSF
AZT & HPA
AZT & IFN.alpha.
AZT & IL-1
AZT & IL-2
AZT & IL-6
AZT & Interferon-.alpha.-2
AZT & Li & EPO
AZT & Li & GM-CSF
AZT & Li & IL-1
AZT & Li & IL-6
AZT & Lymphoblastoid Interferon
AZT & NP (from PHCA or HSA)
AZT & PM-19
AZT & SST
AZT & rIFN.alpha.2
AZT & rsCD4 & rIFN.alpha.A
AZT & rsT4
AZT & sCD4
AZT & srCD4
AZT (Antiviral)
AZT Antiviral
AZT TRANSPLACENTAL CARCINOGENESIS STUDY
AZT+PRO 140
AZT, Antiviral
Antiviral AZT
Apo-Zidovudine
Azidothymidine
Aztec
BB_NC-1012
BPBio1_000403
BRD-K72903603-001-04-6
BSPBio_000365
BSPBio_003153
BW A509U
BW-A 509U
BW-A-509U
BW-A509U
BWA 509U
BWA-509U
BWA509U
C07210
CCRIS 105
CHEBI:10110
CHEBI:127307
CHEMBL129
CID35370
CPD000058351
 
Compound S
Cpd S
D00413
D015215
DB00495
DRG-0004
DS-4152 & AZT
DivK1c_000524
HMS1921J20
HMS2090G11
HMS2092D06
HMS501K06
HSDB 6515
IDI1_000524
Interferon AD + 3'-azido-3'-deoxythymidine
Intron A & AZT
K7 [P Ti2 W10 O40]
KBio1_000524
KBio2_001828
KBio2_004396
KBio2_006964
KBio3_002653
KBioGR_000703
KBioSS_001828
LS-1159
Liposomal AZT-SN-1
Liposomal AZT-SN-3
MLS000028548
MLS001055351
MLS001076358
MLS002153202
MLS002222249
Met-SDF-1.beta. & AZT
Met-SDF-1.beta. & Zidovudine
MolPort-002-507-286
NCGC00023945-03
NCGC00023945-04
NCGC00023945-05
NCGC00023945-08
NCGC00178237-01
NCGC00178237-02
NINDS_000524
NSC 602670
Novo-Azt
PC-SOD+AZT
Prestwick3_000333
Propolis+AZT
Racemic Liposomal AZT
Retrovir
Retrovir (TN)
Retrovir(TM)
SAM002548971
SMR000058351
SN-1-dipalmitoylglycerophospho-AZT (in a lipid vesicle)
SN-3-dipalmitoylglycerophospho-AZT (in a lipid vesicle)
SPBio_000834
SPECTRUM1502109
STK801891
Spectrum2_000927
Spectrum3_001507
Spectrum4_000332
Spectrum5_001101
Spectrum_001348
UNII-4B9XT59T7S
ZDV
ZIDOVUDINE [AZT]
ZINC03779042
ZVD
Zidovudin
Zidovudina
Zidovudina [Spanish]
Zidovudine
Zidovudine (JAN/USP/INN)
Zidovudine EP III
Zidovudine [USAN:INN:BAN:JAN]
Zidovudine+PRO 140
Zidovudinum
Zidovudinum [Latin]
antiviral
azidodeoxythymidine
rIFN-beta seron & AZT
racemic-dipalmitoylglycerophospho-AZT (in a lipid vesicle)
zidovudin
zidovudine
6CyclosporinsPhase 2, Phase 3849
7
InfliximabapprovedPhase 2327170277-31-3
Synonyms:
Ig gamma-1 chain C region
 
Inflectra
Remicade
Remsima
8Interferon beta 1aPhase 2191
9Interferon-betaPhase 2244

Interventional clinical trials:

(show all 19)
idNameStatusNCT IDPhase
1Zidovudine Plus Lamivudine in HTLV-I-associated Myelopathy: a Randomised TrialCompletedNCT00272480Phase 2, Phase 3
2Ciclosporin in HTLV-1 Associated Myelopathy/ Tropical Spastic Paraparesis (HAM/TSP)CompletedNCT00773292Phase 2, Phase 3
3Use Of Valproid Acid To Treat Tropical Spastic Paraparesis/HTLV-1-Associated Myelopathy (TSP/HAM)CompletedNCT00681980Phase 3
4Use of Pentoxifylline in Human T-lymphotropic Virus Type-1 (HTLV-1) DiseasesCompletedNCT01472263Phase 3
5Efficacy and Safety of Tamibarotene(AM80H) for HTLV-1 Associated Myelopathy/ Tropical Spastic Paraparesis (HAM/TSP)Active, not recruitingNCT01343355Phase 2, Phase 3
6Recombinant Human Interferon Beta-1a (Avonex) for the Treatment of Patients With HTLV-1-Associated Myelopathy (HAM)CompletedNCT00001785Phase 2
7Ruxolitinib for Adult T-Cell LeukemiaRecruitingNCT01712659Phase 2
8The HAM Infliximab StudyTerminatedNCT00823641Phase 2
9Hu Mik-Beta-1 to Treat HTLV-1-Associated Myelopathy/Tropical Spastic ParaparesisRecruitingNCT00076843Phase 1
10MRI Brain Studies in Patients With HTLV-1 Associated Myelopathy/Tropical Spastic ParaparesisCompletedNCT00034723
11A Study of Familial and Genetic Aspects of Adult T-Cell: Leukemia/Lymphoma , Tropical Spastic Paraparesis, and Infective DermatitisCompletedNCT00340821
12Assessment of Patients With Multiple Sclerosis (MS)CompletedNCT00001156
13Raltegravir for HAM/TSPRecruitingNCT01867320Phase 0
14Evaluation of Patients With HAM/TSPRecruitingNCT00001778
15Urological Physical Therapy in HTLV-1 With Urinary SymptomsEnrolling by invitationNCT01651819
16Evaluation of the MP Diagnostics HTLV Blot 2.4Enrolling by invitationNCT01467024
17Effect of Raltegravir in Patients With Acute Tropical Spastic Paraparesis - Human T-Lymphotropic Virus 1 InfectionNot yet recruitingNCT02655471Phase 0
18Influence of IL28B Genetic Variation on the Phenotype Infection of HTLV-1Not yet recruitingNCT01754311
19Safety and Efficiency Study of Valproic Acid In HAM/TSPTerminatedNCT00519181

Search NIH Clinical Center for Htlv-1 Associated Myelopathy

Genetic Tests for Htlv-1 Associated Myelopathy

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Anatomical Context for Htlv-1 Associated Myelopathy

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MalaCards organs/tissues related to Htlv-1 Associated Myelopathy:

33
T cells, Spinal cord, B cells, Liver, Brain, Thyroid

Animal Models for Htlv-1 Associated Myelopathy or affiliated genes

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MGI Mouse Phenotypes related to Htlv-1 Associated Myelopathy:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes

Publications for Htlv-1 Associated Myelopathy

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Articles related to Htlv-1 Associated Myelopathy:

(show top 50)    (show all 52)
idTitleAuthorsYear
1
Donor-Derived HTLV-1 Associated Myelopathy After Transplantation: A Call for Targeted Screening. (25772487)
2015
2
Clinical presentation of axial myopathy in two siblings with HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). (25884435)
2015
3
HTLV-1-associated infective dermatitis and probable HTLV-1- associated myelopathy in an adolescent female. (26312674)
2015
4
HTLV-1 associated myelopathy after renal transplantation. (26479201)
2015
5
CD80+ and CD86+ B cells as biomarkers and possible therapeutic targets in HTLV-1 associated myelopathy/tropical spastic paraparesis and multiple sclerosis. (24472094)
2014
6
Atrophy, focal spinal cord lesions and alterations of diffusion tensor imaging (DTI) parameters in asymptomatic virus carriers and patients suffering from human T-lymphotrophic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP). (25227931)
2014
7
Co-presentation of human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis and adult-onset infective dermatitis associated with HTLV-1 infection. (23278610)
2013
8
Clustering of HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) and infective dermatitis associated with HTLV-1 (IDH) in Salvador, Bahia, Brazil. (23932323)
2013
9
Ciclosporin A proof of concept study in patients with active, progressive HTLV-1 associated myelopathy/tropical spastic paraparesis. (22720101)
2012
10
Systems biology approaches reveal a specific interferon-inducible signature in HTLV-1 associated myelopathy. (22291590)
2012
11
Aquaporin-4 antibodies are not related to HTLV-1 associated myelopathy. (22808032)
2012
12
Prevalence of peripheral neuropathy in patients with HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). (21510232)
2011
13
HTLV-1 associated myelopathy/tropical spastic paraparesis: how far have we come? (22519224)
2011
14
Correlation of HTLV-1 Tax genetic diversity with HTLV-1 associated myelopathy/tropical spastic paraparesis progression and HTLV-1a genotypes in an HTLV-1 endemic region in Argentina. (20572090)
2010
15
Sphincter abnormality in polytransfused patient due to paroxysmal nocturnal hemoglobinuria (PNH): initial manifestation of tropical spastic paraparesis/HTLV-1 associated myelopathy (TSP/HAM). (21243260)
2010
16
Case report of HTLV-1 associated myelopathy (HAM) manifested after renal transplantation]. (20411806)
2010
17
Absence of consistent association between human leukocyte antigen-I and -II alleles and human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis risk in an HTLV-1 French Afro-Caribbean population. (20851016)
2010
18
Immunogenetics and the Pathological Mechanisms of Human T-Cell Leukemia VirusType 1- (HTLV-1-)Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP). (20169122)
2010
19
HTLV-1 associated myelopathy diagnosed during lepromatous leprosy reaction treatment: a case report. (20802953)
2010
20
In vivo expression of the HBZ gene of HTLV-1 correlates with proviral load, inflammatory markers and disease severity in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). (19228429)
2009
21
Is human T cell lymphotropic type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) syndrome a neglected disease? (19936247)
2009
22
Evaluation of autonomic malfunction in HTLV-1 associated myelopathy (HAM). (19553162)
2009
23
High HTLV-1 proviral load, a marker for HTLV-1 associated myelopathy/tropical spastic paraparesis, is also detected in patients with infective dermatitis associated with HTLV-1. (19578703)
2009
24
Increased frequency of CD4+T cells expressing fractalkine receptor CX3CR1 in patients with HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP), but its AIDS susceptible polymorphisms are not associated with the disease. (17884099)
2008
25
Histone deacetylase mediated transcriptional activation reduces proviral loads in HTLV-1 associated myelopathy/tropical spastic paraparesis patients. (17717136)
2007
26
Nocturnal hypertension and autonomic dysfunction due to human T-lymphotropic virus type-1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP). (16503269)
2006
27
Human T-cell lymphotropic virus type I (HTLV-1) associated myelopathy and SjAPgren's syndrome representing pulmonary nodular amyloidosis and multiple bullae: Report of an autopsy case. (16609913)
2006
28
Proviral load and immune markers associated with human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in Peru. (17034574)
2006
29
A prospective uncontrolled trial of fermented milk drink containing viable Lactobacillus casei strain Shirota in the treatment of HTLV-1 associated myelopathy/tropical spastic paraparesis. (15961107)
2005
30
Differences in viral and host genetic risk factors for development of human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis between Iranian and Japanese HTLV-1-infected individuals. (15722539)
2005
31
Human T lymphotropic virus type I (HTLV-1) associated myelopathy acquired through a liver transplant. (11762319)
2001
32
Chemokines in chronic progressive neurological diseases: HTLV-1 associated myelopathy and multiple sclerosis. (10190696)
1999
33
Predominant expression of Fas ligand mRNA in CD8+ T lymphocytes in patients with HTLV-1 associated myelopathy. (9817448)
1998
34
Cerebrospinal fluid of HTLV-1 associated myelopathy patients induces axonal sproutings and Schwann cell proliferation in the rat sciatic nerve. (9700698)
1998
35
Persistent oligoclonal expansion of human T-cell leukemia virus type 1-infected circulating cells in patients with Tropical spastic paraparesis/HTLV-1 associated myelopathy. (9671316)
1998
36
CD8 and CD4 T cell-mediated polymyositis complicating the HTLV-1 associated myelopathy. Quantitative evaluation of corticosteroid treatment. (8891056)
1996
37
HTLV-1 associated myelopathy/tropical spastic paraparesis in Egypt. (8912212)
1996
38
Clinical neurophysiological comparative study on HTLV-1 associated myelopathy/tropical spastic paraparesis. (8555734)
1995
39
Cognitive event-related potentials and brain magnetic resonance imaging in HTLV-1 associated myelopathy (HAM). (7836944)
1994
40
Clinical and demographic features of HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) in Rio de Janeiro, Brazil. (8372632)
1993
41
Danazol. A new perspective in the treatment of HTLV-1 associated myelopathy (preliminary report). (1308424)
1992
42
HTLV-1 associated myelopathy/tropical spastic paraparesis with adult T-cell leukemia. (1736016)
1992
43
Post-mortem diagnosis of human T lymphotrophic virus type-1 (HTLV-1) associated myelopathy by detection of HTLV-1 DNA in the spinal cord of a patient with post-transfusional myelopathy. (1791859)
1991
44
HTLV-1 associated myelopathy combined with chronic thyroiditis. (2066716)
1991
45
High ratio of HTLV-1-infected cells in HTLV-1 associated myelopathy (HAM). (2353570)
1990
46
HTLV-1 associated myelopathy in Chile. (2311023)
1990
47
HTLV-1 associated myelopathy in Canada. (2766126)
1989
48
Central motor conduction time in patients with HTLV-1 associated myelopathy. (2741672)
1989
49
HTLV-1 associated myelopathy in an HTLV-1 and HBV double carrier family: report of a case and the mode of vertical transmission of both viruses. (2491206)
1989
50
HTLV-1 associated myelopathy (HAM). (2901451)
1988

Variations for Htlv-1 Associated Myelopathy

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Expression for genes affiliated with Htlv-1 Associated Myelopathy

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Search GEO for disease gene expression data for Htlv-1 Associated Myelopathy.

Pathways for genes affiliated with Htlv-1 Associated Myelopathy

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Pathways related to Htlv-1 Associated Myelopathy according to GeneCards Suite gene sharing:

(show all 36)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
AhR pathway (WikiPathways)
Show member pathways
9.4
29.4IL2, JUN
39.4IL2, JUN
49.4IL2, JUN
5
Show member pathways
9.4IL2, JUN
69.3JUN, MYC
79.3JUN, MYC
89.3JUN, MYC
9
Show member pathways
9.3JUN, MYC
109.3JUN, MYC
119.3JUN, MYC
129.1IL2RA, JUN
13
Show member pathways
9.1IL2, IL2RA
149.1IL2, IL2RA
159.0IL2RA, MYC
16
Show member pathways
9.0HLA-A, IL2, JUN
178.9HLA-A, JUN, MYC
188.8IL2, JUN, MYC
19
Show member pathways
8.6IL2, IL2RA, JUN
208.6IL2, IL2RA, JUN
21
Show member pathways
8.6IL2, IL2RA, JUN
22
Show member pathways
8.6IL2, IL2RA, JUN
23
Show member pathways
8.6IL2, IL2RA, JUN
24
Show member pathways
8.5IL2, IL2RA, MYC
25
Show member pathways
8.5IL2, IL2RA, MYC
268.5IL2, IL2RA, MYC
27
Show member pathways
8.2HLA-A, IL2, IL2RA, JUN
28
Show member pathways
8.2HLA-A, IL2, IL2RA, JUN
29
Show member pathways
8.2HLA-A, IL2, IL2RA, JUN
30
Show member pathways
8.2HLA-A, IL2, IL2RA, JUN
31
Show member pathways
8.0IL2, IL2RA, JUN, MYC
32
Show member pathways
8.0IL2, IL2RA, JUN, MYC
33
Show member pathways
8.0IL2, IL2RA, JUN, MYC
34
Show member pathways
8.0IL2, IL2RA, JUN, MYC
35
Show member pathways
8.0IL2, IL2RA, JUN, MYC
367.5HLA-A, IL2, IL2RA, JUN, MYC

GO Terms for genes affiliated with Htlv-1 Associated Myelopathy

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Biological processes related to Htlv-1 Associated Myelopathy according to GeneCards Suite gene sharing:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of interferon-gamma productionGO:003272910.1HLA-A, IL2
2regulation of T cell homeostatic proliferationGO:00460139.9IL2, IL2RA
3negative regulation of lymphocyte proliferationGO:00506729.8IL2, IL2RA
4positive regulation of fibroblast proliferationGO:00481469.8JUN, MYC
5learningGO:00076129.7CNTN2, JUN
6positive regulation of activated T cell proliferationGO:00421049.6IL2, IL2RA
7positive regulation of T cell differentiationGO:00455829.6IL2, IL2RA
8negative regulation of inflammatory responseGO:00507289.6IL2, IL2RA
9positive regulation of T cell proliferationGO:00421029.4IL2, IL2RA
10positive regulation of cell proliferationGO:00082849.0IL2, JUN, MYC
11immune responseGO:00069558.9HLA-A, IL2, IL2RA
12Fc-epsilon receptor signaling pathwayGO:00380958.6IL2, IL2RA, JUN
13MAPK cascadeGO:00001658.2IL2, IL2RA, MYC

Sources for Htlv-1 Associated Myelopathy

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet