MCID: HTL001
MIFTS: 18

Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis malady

Rare diseases category

Aliases & Classifications for Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

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Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis, Aliases & Descriptions:

Name: Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis 41
Tropical Spastic Paraparesis 41 60
 
Human T-Cell Leukemia Virus Type 1 Associated Myelopathy/tropical Spastic Paraparesis 41
Ham/tsp 41


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


Summaries for Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

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NIH Rare Diseases:41 Htlv-1 associated myelopathy/tropical spastic paraparesis (ham/tsp) is a chronic, progressive disease of the nervous system that affects less than 2 percent of people with htlv-1 infection. signs and symptoms vary but may include progressive weakness, stiff muscles, muscle spasms, backache, a 'weak' bladder, and constipation. the htlv-1 virus can be transmitted from mother to child via breastfeeding or childbirth, from person to person through sexual contact and through blood contact, either by transfusion or by reuse of injection equipment. htlv infection is not passed from person to person by coughing, sneezing, kissing, cuddling or daily social contact.screening of donated blood for htlv-1 has been done in the united states since 1988. last updated: 3/16/2011

MalaCards based summary: Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis, also known as tropical spastic paraparesis, is related to htlv-1 associated myelopathy and tropical spastic paraparesis. An important gene associated with Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis is CX3CR1 (chemokine (C-X3-C motif) receptor 1). Affiliated tissues include t cells, spinal cord and b cells.

Related Diseases for Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

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Graphical network of the top 20 diseases related to Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis:



Diseases related to htlv-1 associated myelopathy/tropical spastic paraparesis

Symptoms for Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

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Drugs & Therapeutics for Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

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Drug clinical trials:

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Genetic Tests for Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

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Anatomical Context for Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

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MalaCards organs/tissues related to Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis:

31
T cells, Spinal cord, B cells

Animal Models for Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis or affiliated genes

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Publications for Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

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Articles related to Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis:

(show all 24)
idTitleAuthorsYear
1
Clinical presentation of axial myopathy in two siblings with HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). (25884435)
2015
2
CD80+ and CD86+ B cells as biomarkers and possible therapeutic targets in HTLV-1 associated myelopathy/tropical spastic paraparesis and multiple sclerosis. (24472094)
2014
3
Atrophy, focal spinal cord lesions and alterations of diffusion tensor imaging (DTI) parameters in asymptomatic virus carriers and patients suffering from human T-lymphotrophic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP). (25227931)
2014
4
Co-presentation of human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis and adult-onset infective dermatitis associated with HTLV-1 infection. (23278610)
2013
5
Clustering of HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) and infective dermatitis associated with HTLV-1 (IDH) in Salvador, Bahia, Brazil. (23932323)
2013
6
Ciclosporin A proof of concept study in patients with active, progressive HTLV-1 associated myelopathy/tropical spastic paraparesis. (22720101)
2012
7
Prevalence of peripheral neuropathy in patients with HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). (21510232)
2011
8
HTLV-1 associated myelopathy/tropical spastic paraparesis: how far have we come? (22519224)
2011
9
Correlation of HTLV-1 Tax genetic diversity with HTLV-1 associated myelopathy/tropical spastic paraparesis progression and HTLV-1a genotypes in an HTLV-1 endemic region in Argentina. (20572090)
2010
10
Absence of consistent association between human leukocyte antigen-I and -II alleles and human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis risk in an HTLV-1 French Afro-Caribbean population. (20851016)
2010
11
Immunogenetics and the Pathological Mechanisms of Human T-Cell Leukemia VirusType 1- (HTLV-1-)Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP). (20169122)
2010
12
In vivo expression of the HBZ gene of HTLV-1 correlates with proviral load, inflammatory markers and disease severity in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP). (19228429)
2009
13
Is human T cell lymphotropic type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) syndrome a neglected disease? (19936247)
2009
14
High HTLV-1 proviral load, a marker for HTLV-1 associated myelopathy/tropical spastic paraparesis, is also detected in patients with infective dermatitis associated with HTLV-1. (19578703)
2009
15
Increased frequency of CD4+T cells expressing fractalkine receptor CX3CR1 in patients with HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP), but its AIDS susceptible polymorphisms are not associated with the disease. (17884099)
2008
16
Histone deacetylase mediated transcriptional activation reduces proviral loads in HTLV-1 associated myelopathy/tropical spastic paraparesis patients. (17717136)
2007
17
Nocturnal hypertension and autonomic dysfunction due to human T-lymphotropic virus type-1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP). (16503269)
2006
18
Proviral load and immune markers associated with human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in Peru. (17034574)
2006
19
A prospective uncontrolled trial of fermented milk drink containing viable Lactobacillus casei strain Shirota in the treatment of HTLV-1 associated myelopathy/tropical spastic paraparesis. (15961107)
2005
20
Differences in viral and host genetic risk factors for development of human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis between Iranian and Japanese HTLV-1-infected individuals. (15722539)
2005
21
HTLV-1 associated myelopathy/tropical spastic paraparesis in Egypt. (8912212)
1996
22
Clinical neurophysiological comparative study on HTLV-1 associated myelopathy/tropical spastic paraparesis. (8555734)
1995
23
Clinical and demographic features of HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) in Rio de Janeiro, Brazil. (8372632)
1993
24
HTLV-1 associated myelopathy/tropical spastic paraparesis with adult T-cell leukemia. (1736016)
1992

Variations for Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

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Expression for genes affiliated with Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

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Search GEO for disease gene expression data for Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis.

Pathways for genes affiliated with Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

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Compounds for genes affiliated with Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

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GO Terms for genes affiliated with Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

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Products for genes affiliated with Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

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  • Antibodies
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Sources for Htlv-1 Associated Myelopathy/tropical Spastic Paraparesis

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3CDC
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